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Daily Archives: November 7, 2021
Al Ansari elected to FIFPro Board of Directors – The Peninsula Qatar
Posted: November 7, 2021 at 12:00 pm
Doha: The International Federation of Professional Footballers (FIFPro) has announced the election of Salman Ahmed Al Ansari as a member of the Board of Directors of FIFPro (Asia and Oceania Division) during the elections that took place during the General Assembly of FIFPro Asia and Oceania Division.
Al Ansari will be a member of the FIFPro Asia & Oceania Board of Directors for the term 2021-25.
On this occasion, Abdulrahman Al Kuwari, President of the Qatar Players Association (QPA), said, We are pleased that Salman Al Ansari has been elected as a member of the Board of Directors of FIFPro (Asia and Oceania), which reflects the confidence gained by Al Ansari during his presidency of the Association at the continental and international levels. We wish the best of success to Mr. Al Ansari.Ibrahim Al Ghanim, Vice-President of the QPA, said: The election of Mr. Salman Al Ansari is a result of the nature of the work he did during the years in which he founded and headed the association, and we hope he is successful in carrying out his duties.
Al Ansari has been elected alongside six members of the Board of Directors of FIFPro (Asia and Oceania), which are Takuya Yamazaki (Japan), Catherine Gill (Australia), Cyrus Confectioner (India), Anna Green (New Zealand), Izham Ismail (Malaysia).
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A week in pictures: news from around the UK and world – The Northern Echo
Posted: at 12:00 pm
HERE are some of the best pictures of the week from around the UK and world.
Tongan activist Uili Lousi stands alongside 'Flare Oceania 2021', created by artist John Gerrard, a real-time moving image showing a simulation of the seas around Tonga with the flag/flare embedded in it.
The image is displayed on a screen on the South Facade of the University of Glasgow to mark Ocean Day at the COP26 climate summit and to raise awareness that the very existence of nations like Tonga are under threat due to the heating of the ocean and rising sea levels.
Also shown is the Italian Airforce acrobatic squad fly above the Monument of the Unknown Soldier, in Romey; and a spectacular display of the Northern Lights seen over Derwentwater, near Keswick in the Lake District.
Keep up to date with all the latest news on our website, or follow us on Facebook, Twitter and Instagram.
You can also follow our dedicated County Durham Facebook page for all the latest in the area by clicking here.
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Have you got a story for us? Contact our newsdesk on newsdesk@nne.co.uk or contact 01325 505054
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A week in pictures: news from around the UK and world - The Northern Echo
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Greta leads thousands in protest and two former VPs: day five of Cop26 – North Wales Chronicle
Posted: at 12:00 pm
The fifth day of the Cop26 climate talks in Glasgow focused on the streets as thousands of protesters took part in a youth march, while in the blue zone the theme of events was also youth as well as oceans.
Here are some of the takeaways from day five:
Naked warning from Greta
Thousands of young activists joined climate campaigner Greta Thunberg on a march through the streets of Glasgow.
In a speech in George Square, the Swedish teenager criticised the Cop26 summit as a two-week festival of business as usual and blah blah blah.
She told the crowd: The voices of future generations are drowning in their greenwash and empty words and promises. But the facts do not lie. And we know that our emperors are naked.
Al Gores Churchillian stance on renewables
Former US vice-president Al Gore channelled Churchill in a speech to delegates, referencing the wartime prime ministers warning on the rise of fascism we are now entering a period of consequences and calling on them to make it a period of solutions.
He also highlighted an unusual type of renewable resource political will.
He said: We have the urgency, we have the tools we need to solve the climate crisis, we need the legislation. The only missing element is sufficient political will.
But political will is itself a renewable resource, and legislators who are leading in every single country can renew that political will and then translate it into effective solutions.
The jobs not done for John Kerry
Meanwhile, another former US vice-president was in the building as John Kerry, now the US special presidential envoy on climate, told delegates it was job not done.
He hailed the flurry of announcements on phasing out coal, cutting methane emissions, delivering green finance and protecting forests in the first days of the climate summit.
But he said there needed to be a deal out of the talks that was a strong statement and implementable, warning: Let me emphasise as strongly as I can: job not done, job not done the day this ends.
Politicians need Mr Motivator
A number of Scottish journalists were turned away at the door of an event, where Cop26 President Alok Sharma and Scotlands First Minister Nicola Sturgeon were due to respond to demands from youth climate activists, due to space concerns.
Although the rebuff came as something of a blessing in disguise when the youngsters in charge made attendees perform an energiser, where they were told to stand and shake various parts of their body in response to questions posed by the moderators.
Apparently, Mr Sharma missed the energiser, if his speech later in the session was anything to go by.
Mothers call for clean air
The mother of Ella Kissi-Debrah, who died age nine from chronic asthma brought on by Londons polluted air, was among a global coalition of mothers fighting to clean up the air in their home countries.
Unless the air is clean, we are never going to resolve climate change, Rosamund Kissi-Debrah told journalists following a Cop26 fringe event.
It is linked to biodiversity, acid rain, global warming and human health one in five premature deaths are due to air pollution and that is why I am here.
Heated warning on warming oceans
On ocean day at the summit, Tongan activist Uili Lousi highlighted an artwork created to illustrate the danger of warming oceans.
Flare Oceania 2021, created by artist John Gerrard, depicts a real-time moving image showing a simulation of the seas around Tonga with a burning flare embedded in it acting as a flag of climate emergency and a call to action before nations such as Tonga disappear under rising sea levels.
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Greta leads thousands in protest and two former VPs: day five of Cop26 - North Wales Chronicle
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Premium Cruise Brands to Expand Restart to More Destinations – Cruise Industry News
Posted: at 12:00 pm
As the cruise restart reaches new heights, premium operators are expanding, with more ships restarting in more destinations, including South Africa and the Panama Canal.
Cruise Industry News looked into the restart status of six key brands:
Celebrity CruisesStatus:Eight ships currently in service; two more set to follow by Dec. 1Ships:Celebrity Apex, Celebrity Edge, Celebrity Equinox, Celebrity Flora, Celebrity Millennium, Celebrity Silhouette, Celebrity Summit and Celebrity Xpedition currently in service; Celebrity Constellation and Celebrity Reflection set to follow in NovemberRegions:Caribbean, Bahamas and Galapagos
Celebrity Cruises resumed guest service in June 2021 with a program in the Caribbean. Following a bold restart plan, the company added seven more cruise ships into the active lineup by the end of July, returning to several destinations, including the Mediterranean, Alaska and the Galapagos
Now, Celebrity is ready to launch a new phase of its resumption program, adding two more ships into active service by Dec. 1.
The brand is also returning to Tampa, where the Celebrity Constellation is set to welcome guests back on Nov. 7.
Holland America LineStatus: Four ships currently in service; one more set to follow by Dec. 1Ships:Eurodam, Koningsdam, Nieuw Amsterdam and Rotterdam in service; Nieuw Statendam set to follow Regions:Atlantic, Caribbean, Mexico and California
After a 16-month hiatus, Holland America Line resumed guest service in July 2021 with a summer season in Alaska. The brand later expanded its restart to the Mediterranean and the West Coast, adding two more ships into the active lineup.
Recently, on Oct. 20, the Carnival Corporation premium brand reached a major milestone, celebrating the maiden voyage of the new Rotterdam. The 2021-built vessel is currently sailing on its first transatlantic crossing, ahead of an inaugural season in the Caribbean.
Now, the Nieuw Statendam is set to resume service next. Complementing the offer in the Caribbean, the 2018-built vessel is welcoming guests back in Fort Lauderdale, on Nov. 21.
Princess CruisesStatus:Six ships currently in service; two more set to follow by Dec. 1Ships:Majestic Princess, Regal Princess, Sky Princess, Grand Princess, Emerald Princess and Ruby Princess in service; Caribbean Princess and Enchanted Princess set to followRegions:Caribbean, Mexico, California and Panama Canal
After concluding its first post-pandemic seasons in the United Kingdom and the Alaska, Princess Cruises is now onto a new phase of its restart program.
The brand is currently offering cruises to the Caribbean, the Mexican Riviera, the California Coast and the Panama Canal, with six ships in revenue service.
Sailing from Los Angeles, San Francisco and Port Everglades, the active fleet is soon being joined by two more vessels: the Caribbean Princess and the Enchanted Princess in the Caribbean
Both ships are offering additional itinerary choices in the Caribbean, while the Enchanted Princess is also embarking on its inaugural season. The 2020-built ship is set to welcome its first guests on Nov. 10 at Port Everglades.
Oceania CruisesStatus:Two ships currently in service; one more set to follow in DecemberShips:Marina and Riviera in service; Insignia set to followRegions:Mediterranean, Atlantic and Panama Canal
Oceania Cruises currently has two vessels in service in Europe, the Marina and the Riviera.
The brand first welcomed guests back in August, with the Marina sailing a series of cruises to Western Europe, the Mediterranean, and the Greek Isles. The Riviera joined the active lineup in October offering additional itineraries in the Mediterranean.
Both ships vessels are set to cross the Atlantic in November ahead of winter seasons in the Caribbean.
In December, a third ship is resuming service for the upper-premium brand: the Insignia. The 700-guest vessel is set to offer a Panama Canal cruise before kicking off its epic six-month-long "Around the World in 180 Days" voyage.
Cunard LineStatus:One ship currently in service; one more set to follow in NovemberShip:Queen Elizabeth in service; Queen Mary 2 set to followRegions:United Kingdom, Western Europe, Atlantic Islands, Mediterranean and Atlantic
Cunard Line returned to guest operations in August after a 17-month break. The brand first welcomed guests back in the United Kingdom, with the Queen Elizabeth offering a series of domesticcruises around the British Islands.
The 2000-guest vessel later resumed international operations sailing itineraries to Western Europe, the Mediterranean and the Atlantic Islands.
After a recent refit, the Queen Mary 2 is now set to return offering cruises in Northern Europe and the Canaries. The vessel is departing Southampton on a its first cruise in over 20 months on Nov. 28.
AzamaraStatus:Two ship currently in service; one more set to follow in January Ship:Azamara Quest and Azamara Journey in service; Azamara Pursuit set to followRegions:Mediterranean, Caribbean, South Africa and Canaries
In August, the Azamara Quest became the first vessel to resume service for Azamara. The ship welcomed guests back with a program of Greece-based Eastern Mediterranean cruises.
The Azamara Journey later joined the active lineup in Europe. After a refit in Cdiz, the kicked off a series of Europe sailings in October offering additional itinerary choices in the Mediterranean.
Azamara is now ready to launch winter programs in the Canary Islands and the Caribbean, using both vessels.
Recently the brand also confirmed its return to South African waters. The Azamara Pursuit will sail in the region from January to March 2022, offering six back-to-back voyages.
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The Supreme Court Ruling That Led To 70,000 Forced …
Posted: at 11:58 am
DAVID BIANCULLI, HOST:
This is FRESH AIR. I'm David Bianculli, editor of the website TV Worth Watching sitting in for Terry Gross. One of the worst Supreme Court decisions in history, according to our guest journalist Adam Cohen, was the 1927 decision upholding a state's right to forcibly sterilize a person considered unfit to procreate - unfit because they were deemed to be mentally deficient. That decision is part of a larger chapter of American history in which the eugenics movement was behind preventing so-called mentally deficient people from procreating through not allowing them to marry, sterilizing them and segregating them in special colonies.
The Nazis borrowed some ideas from American eugenicists. The eugenics movement also influenced the 1924 Immigration Act, which was designed in part to keep out Italians and Eastern European Jews. Adam Cohen's book titled "Imbeciles" is about the eugenics movement in the early 20th century and the Supreme Court case legalizing sterilization. Cohen is a former member of The New York Times editorial board and a former senior writer for Time magazine. Terry Gross spoke to him last year when his book was first published. It's just come out in paperback.
(SOUNDBITE OF ARCHIVED BROADCAST)
TERRY GROSS, HOST:
Adam Cohen, welcome to FRESH AIR. Let's start with what the eugenicists believed.
ADAM COHEN: They embraced the new genetics that was emerging in their era. And they believed that it could be used to perfect the human race. The word eugenics was actually coined by Francis Galton, who was a half-cousin of Charles Darwin, and it really derived a lot from Darwinian ideas. The eugenicists looked at evolution and survival of the fittest as Darwin was describing it. And they believed, we can help nature along if we just plan who reproduces and who doesn't reproduce.
GROSS: And who was considered unworthy of reproducing?
COHEN: Well, at the beginning, Galton looked at geniuses throughout history and looked to see if genius was genetic within families. And he believed that it was. But overtime, eugenics expanded quite a bit. And by the time it got to America, there were all kinds of categories of people who were deemed to be unfit, including people who were deaf, blind, diseased, poor was a big category, indolent.
So it was really in the eye of the beholder. People looked around, and they saw human qualities they didn't like, and they thought, we can really breed these out.
GROSS: And you left out feebleminded. What did feebleminded mean?
COHEN: Yes, feebleminded was really the craze in American eugenics. There was this idea that we were being drowned in a tide of feeblemindedness, that basically unintelligent people were taking over, reproducing more quickly than the intelligent people. But it was also a very malleable term that was used to define large categories of people that, again, were disliked by someone who was in the decision-making position. So women who were thought to be overly interested in sex - licentious - sometimes deemed feebleminded. It was a broad category. And it was very hard to prove at one of these feeblemindedness hearings that you were not feebleminded.
GROSS: So what sent you back to this unfortunate chapter of American history?
COHEN: Well, when I was in law school, I had heard of the case Buck v. Bell from 1927 when the Supreme Court upheld eugenic sterilization. But it wasn't formally taught in at least my class. And it's not taught in many Constitutional Law classes. But, you know, we knew it existed. And we knew the famous phrase that Justice Oliver Wendell Holmes wrote in the decision - three generations of imbeciles are enough. When I was thinking about something I wanted to write about, I was interested in the Supreme Court, but in many ways, I believe you can learn more about an institution and more about an ideal like justice if you look at where it's gone wrong rather than where it's gone right. And in any list of Supreme Court decisions that are terribly wrong, any list of the worst Supreme Court decisions, Buck v. Bell would have to rank very highly.
GROSS: And we'll get to more about that a little bit later. I want to get to the Nazis because I was dismayed to read that the Nazis actually borrowed from the U.S. eugenics sterilization program. What did the Nazis take from us?
COHEN: Well, we really were on the cutting edge. We were doing a lot of this in the 1910s and 1920s. Indiana adopted a eugenic sterilization law - America's first - in 1907. We were writing the eugenics sterilization statutes that decided who should be sterilized. We also had people who were writing a lot of, you know, what might be thought of as pro-Arian theories. So you have people like Madison Grant who wrote a very popular book called "The Passing Of The Great Race," which really talked about the superiority of Nordics, as he called them, and how they were endangered by all the brown people and the non-Nordics who were taking over.
A lot of those ideas were really precursors to Nazism. And also, people forget now, but there was - you know, there was some strong pro-Nazi sentiment in the United States before World War II. In New York, there were pro-Nazi rallies. In some intellectual circles it was not uncommon to find people who actually espoused Nazism. So one of the characters in my book, Harry Laughlin, who ran the Eugenics Record Office on Long Island, a guy who grew up in Missouri, a one-time agriculture professor, he was pro-Nazi. He corresponded with Nazi scientists. And he wrote with pride in his eugenic journal that the Nazis were looking to his model statute and American eugenics to plan their racial program.
GROSS: When immigration is such a contested issue, it's very interesting to learn - 'cause I didn't know this - that the immigration law of 1924 is connected to the eugenics movement. What was the law and how was it connected to eugenics?
COHEN: Yeah, so the 1924 law really changed American immigration dramatically whereas in the old days, people would pretty much just show up at Ellis Island. The people who supported the Immigration Act of 1924 wanted to maintain the racial composition of the United States, so they imposed national quotas, which actually set the immigration from different countries on what that country's percentage of the population was in 1890. And the idea was that was a time when there were a lot of, you know, so-called Nordics in the United States.
So by imposing these national quotas, more people would come in from places like England and fewer would come in from Eastern Europe and Italy. And a big concern was, for these folks, the immigration of particularly Eastern European Jews and Italians. And the degree to which eugenics was just squarely in the discussion of the Act was rather shocking. One of the villains of my book, Harry Laughlin, not only testified repeatedly about eugenics while Congress was considering the law, but he was actually appointed expert eugenics agent by Congress. And when I was looking through his papers in Missouri, there was letterhead - the U.S. Immigration Committee. It said, Harry Laughlin, Expert Eugenics Agent - kind of chilling.
GROSS: So were Jews from Eastern Europe and Italians considered mentally deficient?
COHEN: They were. And there was a lot of bogus science at the time. And there was one well-publicized study that purported to find that between 40 and 50 percent of Jews who were arriving from Eastern Europe at Ellis Island were feebleminded. And it's really shocking to go back and read the way in which people wrote about immigrants in those times, and it definitely does parallel things going on today, but even harsher rhetoric.
You know, so someone like Madison Grant, this popular eugenics writer, the way he wrote about walking around his beloved city of New York and seeing these Polish Jews walking down the street in their, you know, ugly Polish-Jewish clothing and knowing that they were trying to join our society and marry our women, it was really - it was very crude and it was a great fear at the time. And, you know, one place in which this is reflected is in the book, "The Great Gatsby," which, you know, unfolds in the 1920s. Tom Buchanan, who is Daisy Buchanan's husband, at one point at a luncheon just goes off about how he's reading this great book, which appears to be a reference to one of these two best-sellers of the time, and he says that he, you know, he's shocked to see that, you know, all these colored people are rising up around the world and they're going to swamp the white race. This was a real fear of the middle and, particularly, upper classes at the time.
GROSS: So the immigration law of 1924, which should we say limited or prevented Jews and Italians from immigrating?
COHEN: Limited extremely. So there were some but the numbers fell so dramatically.
GROSS: OK. So that law was passed just in time for the Holocaust. So how did that come into play and therefore how did eugenics come into play in preventing Jews from seeking safe haven in the U.S. during the Holocaust?
COHEN: It absolutely did prevent many Jews from coming to America at the time. Under the old immigration laws, where it was pretty much, you know, show up, they would've been able to immigrate. But suddenly they were, you know, trapped by very unfavorable national quotas. So this really was a reason that so many Jews were turned away. And one very poignant aspect of it that I thought about as I was working on the book is in the late '90s, some correspondence appeared - was uncovered - in which Otto Frank was writing repeatedly to the State Department begging for visas for himself and his wife and his two daughters, Margot and Anne, and was turned down and that was because there were now these quotas in place. And if they had not been, it seems clear that he would've been able to get a visa for his whole family, including his daughter, Anne Frank.
So when we think about the fact that Anne Frank died in a concentration camp, we're often told that it was because the Nazis believed that Jews were genetically inferior, that they were lesser than Aryans. That's true, but to some extent, Anne Frank died in a concentration camp because the U.S. Congress believed that as well.
GROSS: That's just chilling. So in talking about that 1924 immigration law, were Asians included too?
COHEN: Yeah. Well, it - you know, the national quota...
GROSS: Or I should say excluded too (laughter).
COHEN: Yeah. Well, the national quota did not work out well for them 'cause there were so few around in 1890. And on the West Coast, it was actually a big issue. So Asians were another target.
GROSS: And what did the eugenicists have to say about Asians?
COHEN: Yeah, you know, not Nordic types, so not good.
GROSS: If you're just joining us, my guest is journalist Adam Cohen. We're talking about his new book, "Imbeciles: The Supreme Court, American Eugenics, And The Sterilization Of Carrie Buck." We'll talk more about the eugenics movement here in the U.S. after we take a short break. This is FRESH AIR.
(SOUNDBITE OF THE WESTERLIES SONG, "PLEASE KEEP THAT TRAIN AWAY FROM MY DOOR")
GROSS: If you're just joining us, my guest is Adam Cohen. We're talking about a very disturbing chapter in American history, the chapter of the eugenics movement early in the 20th century. His book is called "Imbeciles: The Supreme Court, American Eugenics, And The Sterilization Of Carrie Buck."
So the eugenicists were partly behind the 1924 Immigration Law. There were laws that prevented people from marrying if they were deemed hereditarily unworthy. There were laws that allowed people considered feebleminded to be isolated in institutions in the U.S. What was the logic behind institutionalizing people who were deemed feebleminded?
COHEN: Well, the eugenicists saw two threats to the national gene pool. One was the external one, which they were addressing through immigration law. The other was the internal one, what to do about the people who were already here. And they had a few ideas. The first eugenics law in the United States was passed in Connecticut in 1895. And it was a law against certain kinds of marriages. They were trying to stop certain unfit people from reproducing through marriage. It wasn't really what they wanted, though, because they realized that people would just reproduce outside of marriage.
So their next idea was what they called segregation. The idea was to get people who were deemed unfit institutionalized during their reproductive year, particularly for women, keep them there, make sure that they didn't reproduce. And then women were often let go when they had passed their reproductive years 'cause they were no longer a threat to the gene pool. That had a problem, too, though. And the problem was that it would be really expensive to segregate, institutionalize, the number of people the eugenicists were worried about.
One of my villains in the book, Harry Laughlin, gave a major address in which he said that to get rid of the, you know, the one-tenth of the country that he was worried about, as many as 15 million people would have to be sterilized. So you couldn't put 15 million people in institutions. They understood that it just wasn't economically feasible. So their next idea was eugenic sterilization. And that allowed for a model in which they would take people in to institutions, eugenically sterilize them, and then they could let them go because they were no longer a threat. So that's why eugenic sterilization really became the main model that the eugenicists embraced and that many states enacted laws to allow.
GROSS: And this was involuntary sterilization. What were the techniques that were used to sterilize men or women?
COHEN: Yeah, you know, for men, it was something like a vasectomy. For women, it was a salpingectomy, where they cauterized the path that the egg takes towards fertilization. It was not - in the case of women - not minor surgery. And when you read about what happened, you know, it's many, many days of recovery and, you know, it had certain dangers attached to it. And, you know, a lot of the science was still quite new.
GROSS: When you think of what surgery was like in the 1920s and the risk of infection, that's - it's so risky, you know, even beyond the - just the wrongness of forcibly sterilizing people, to subject them to surgery and the possibility of terrible infections just seems so - it's just so horrible that our government did that.
COHEN: It seems horribly invasive. And when you add on to all that the fact that in many, many cases the women involved were not told what was being done to them. They might be told that they were having an appendectomy. Or - you know, they weren't being told that the government has decided that you are unfit to reproduce and we're then going to have surgery on you. So that just compounds the horror of the situation.
GROSS: This was an era when birth control was still controversial but was before the era where abortion was legalized. Abortion is such a lightning rod issue now in the United States and it has been for decades. So one of the major groups that opposes abortions, of course, is the Catholic Church. Where was the Catholic Church on the issue of forced sterilization?
COHEN: Well, you know, the Catholic Church was actually fairly heroic on this issue. And conservatives often point to the eugenics era as one where they feel, you know, they got it right. And when it reaches the Supreme Court, the only dissenting justice in the case of Buck v. Bell is the only Catholic on the court. So at a time when, you know, it's hard to imagine, but there weren't public interest groups that were looking out for the interests of women, of institutionalized people.
A lot of the progressives of the era, including Teddy Roosevelt, Louis Brandeis, the great progressive justice and even people associated with the fledgling ACLU, American Civil Liberties Union, they supported eugenics. So it was really a situation where there were almost no advocates for the women involved. The Catholic Church was one because they believed that - not only did they believe in reproduction, but they believed that people should be judged by their souls, not by these attributes that the eugenicists were so focused on. And in many states, when there was a eugenic sterilization bill before the legislature, the people who showed up to oppose it were Catholics, they were priests, they were nuns. And there were states like Louisiana with high Catholic populations where eugenic sterilization laws were voted down really because of the Catholic Church.
GROSS: Carrie Buck was chosen to be the subject for a test case for a Virginia law allowing forced sterilization of people considered feebleminded. And that case made it to the Supreme Court. It's this case that's the main focus of your book. And it resulted in a decision that allowed states to forcibly sterilize people deemed feebleminded. Why was a test case in Virginia considered necessary?
COHEN: In other states, they just passed laws and began sterilizing people. But one of the characters in my book, a lawyer named Aubrey Strode, really prevailed upon the Virginia hospitals to say you shouldn't sterilize anyone until we know that it's constitutional. And under his legal advice, that's what everyone agreed. So they decided that they would set up a test case, get it into the Virginia court system and, you know, hope that it went as high as the U.S. Supreme Court to get judicial approval for their law.
GROSS: So the person chosen as the plaintiff was Carrie Buck. She was, at the time - an inmate I think is the right word - an inmate of the Colony for Epileptics and the Feebleminded. What was this colony and why were epileptics and the, quote, "feebleminded" pooled together?
COHEN: Well, it started as an epileptic colony. In a few years, they expanded it to add feebleminded because they had so many people who were being designated feebleminded and they didn't really have a great place to put them all. And a lot of the hospitals were getting crowded. And at the time, there was this idea that, for both epileptics and the feebleminded, if you put them out in the country in a farm-like setting, gave them chores, that the fresh air would help with their recovery, although really no one was recovering.
GROSS: So why was Carrie Buck in this institution?
COHEN: Well, it's a terribly sad story. She was a little girl who was being raised by a single mother in poverty in Charlottesville - sometimes on the streets of Charlottesville. She got taken in by a foster family that wanted to help her to a better life or so it seemed. But they actually made her do all the work and didn't treat her very well. And she wasn't allowed to call her foster parents Mother and Father. And then eventually, she's raped by a nephew of the family and is pregnant out of wedlock.
At the time, that was a huge scandal in and of itself. And then when you add in the fact that if the facts came to light, their nephew could be prosecuted for a very serious crime, the foster family decided to have a feeblemindedness hearing for Carrie Buck and to testify that she was actually they said both epileptic and feebleminded - although, you know, total lies. She was not epileptic and never had a seizure. And everyone sort of agreed towards the end of her life that she had never been epileptic. She also wasn't feebleminded. She was doing well in school until her foster family took her out of school it appears because they wanted her to do more work around the house and to let her out to neighbors to do their housework as well.
So this is this poor young woman, really nothing wrong with her physically or mentally, a victim of, you know, a terrible sexual assault. And there's a little hearing. She's declared feebleminded. And she gets sent off to the Colony for Epileptics and Feebleminded, where as it happens, her mother, who probably was also not feebleminded, was already an inmate.
BIANCULLI: Adam Cohen speaking to Terry Gross last year. His book "Imbeciles" is now out in paperback. After a break, we'll hear more about the 1927 Supreme Court decision that includes the now-infamous line, three generations of imbeciles are enough. And film critic David Edelstein will review the new movie "Wilson" starring Woody Harrelson. I'm David Bianculli, and this is FRESH AIR.
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BIANCULLI: This is FRESH AIR. I'm David Bianculli in for Terry Gross back with more of Terry's 2016 interview with Adam Cohen. His book "Imbeciles" is now out in paperback. It's about the American eugenics movement and the 1927 Supreme Court decision upholding a state's right to forcibly sterilize people considered mentally deficient so that they wouldn't reproduce and degrade America's gene pool.
The plaintiff in the case was Carrie Buck, a young woman who was taken in by a foster family that didn't treat her well. When Buck was 17, she became pregnant after being raped by one of the family's nephews. Her foster parents asked for a hearing to have her sterilized. They testified that she was feebleminded and epileptic. Although Buck was neither, she was sent to a special colony.
(SOUNDBITE OF ARCHIVED BROADCAST)
GROSS: So Carrie Buck is sent to this colony for epileptics and the feebleminded. And after - I guess after she gives birth because she's pregnant during her hearing...
COHEN: Yes, yes...
GROSS: After she gives birth, she's sterilized.
COHEN: Yes. Actually, her foster family ends up taking her child and raising it as their own. And then when she's at the colony, the guy who's running the colony, Dr. Albert Priddy, is on the prowl. He's looking for someone to put at the center of this test case that they want to bring. So he's looking for someone to sterilize. And he sees Carrie Buck when she comes in. He does the examination himself. And there are a lot of things about her that excite him. She's deemed to be feeble-minded. She has a mother who's feebleminded. So that's good because you can show some genetics. And then they're hoping that the baby could be determined to feebleminded, too. Then you could really show a genetic pattern of feeblemindedness.
The fact that she had been pregnant out of wedlock was another strike against her. So he fixes on her and thinks, Carrie Buck is going to be the perfect potential plaintiff. And also, the pregnancy was important because the great fear at the time was that the feebleminded were reproducing very rapidly and they were going to take over the country. So if you have a woman who, you know, at 17 is already pregnant with what they would say was yet another feebleminded person, you know, she just fit everyone's fears of what was happening. So he chooses her, and then under the Virginia law, they have to have a sterilization hearing at the colony, which they do.
And they give her a lawyer who is really not a lawyer for her. It's really someone who had been the chairman of the board of the colony and was sympathetic to the colony's side. And they have a bit of a sham hearing where she's determined to be a suitable person for sterilization. They vote to sterilizer her. And that is the order that then gets challenged by Carrie as the plaintiff, first in the Virginia court system and then in the Supreme Court.
GROSS: So what was her representation like in the Supreme Court?
COHEN: Well, it was the same terrible lawyer who really was not on her side. And, you know, to read the briefs for her and against her is a dispiriting experience because the lawyer who was trying to get her sterilized actually did a very good job and wrote very complete, lengthy briefs. Carrie's lawyer wrote short briefs that missed some of the most important arguments on her side and then contained some facts and arguments that actually seemed to argue for her being sterilized. So he was not a lawyer who was really interested in preventing her sterilization.
GROSS: So Carrie Buck loses the case in the Supreme Court. The Court upholds Virginia's right to sterilize her. And Oliver Wendell Holmes, who I think was considered a progressive, writes the decision upholding forced sterilization. What was behind his opinion?
COHEN: Well, for me, this was one of the saddest parts of reading up on the case 'cause when I was in law school, Oliver Wendell Holmes was really held up as the pinnacle of American justice, as a heroic figure, someone who was wounded three times in the Civil War, as a great thinker and really a model for all aspiring lawyers and judges. He actually was in many ways - although he had this reputation of being a progressive - not a progressive and not a very good guy. He had been raised in the Boston Brahmin world of that era. His father was actually the man who coined the phrase Boston Brahmin. And that phrase embodied everything that they believed about themselves, right?
They took the word Brahmin from the Indian caste system. They believed that they were America's highest caste. And Holmes was raised to believe that he and his wealthy, quote, you know, "wellborn" Boston neighbors were the best people in the country or the world. And that was something that began to influence his approach to the law before - long before the Buck v. Bell case came to the Supreme Court. Oliver Wendell Holmes had written about eugenics, which he supported. And when the case got to him, well, he was just absolutely the wrong person for Carrie Buck to have decide her fate.
GROSS: So what did he write in his majority decision?
COHEN: You know, it was a very short decision, just about, you know, five paragraphs. But he packed in so many horrible ideas and misinformation that it was quite impressive. He had this famous phrase that is reverberated over the generations, three generations of imbeciles are enough. And by that, he meant Carrie Buck's mother, Carrie Buck and Carrie Buck's daughter. And a somewhat pedantic point but, you know, there were actually very precise categories of mental defect at that time. And the lowest category was idiot, the middle level was imbecile and the highest level was moron. Carrie and her mother were both determined by the colony after extensive, you know, unreliable testing to be morons. But Oliver Wendell Holmes actually, you know, demoted them in his decision and called them imbeciles, which was a lower category.
GROSS: So, you know, a lot of people just throw around words like imbecile and moron as, like, colorful ways of saying, God, that was such a stupid thing to do, what an imbecile or, oh, you behaved like such a moron. But I had no idea that those words had actually been official categories that were used to punish people, sterilize them or keep them in a colony.
COHEN: They were, and, you know, Carrie was a middle-grade moron according to these, you know, completely unreliable tests. So they were. But so the word imbeciles - you know, Oliver Wendell Holmes was a great wordsmith. And he chose imbeciles, I think, very intentionally both because it packs a lot of power into the word itself. But also, it was even more degrading than - you know, than the category that Carrie, you know, rightfully should've had. But, you know, beyond that terrible phrase - and it was terrible - you know, imagine you're going to the Supreme Court and hoping to have your right of bodily integrity not to have an operation to sterilize you performed on you and the response of the Supreme Court 8-1 is three generations of imbeciles are enough.
But beyond that, what was really shocking about the decision is that rather than just decide the case before them, which is what the Supreme Court is supposed to do, and which Oliver Wendell Holmes as a matter of his own judicial philosophy, he did believe in just narrowly ruling on the case before him, not having broad, broad edicts. In this one case, he writes not only that Carrie Buck should be sterilized, that the Virginia law is constitutional, but he urges America to do more eugenic sterilization. And he has this terrible passage where he says, it is better for all the world if instead of waiting to execute degenerate offspring for crime or to let them starve for their imbecility, society can prevent those who are manifestly unfit from continuing their kind. So at a time when we're hoping that maybe there'll be some insipient grassroots opposition to eugenics, an opposition to these terrible eugenic sterilization laws, the U.S. Supreme Court by an 8-1 vote by the pen of the great Oliver Wendell Holmes is saying, no, no, do more of this, pass more laws, sterilize more people. The nation needs it.
GROSS: I don't know, I'm speechless.
BIANCULLI: We're listening to Terry's interview with Adam Cohen, author of the book "Imbeciles: The Supreme Court, American Eugenics, And The Sterilization Of Carrie Buck." Terry spoke with Adam Cohen last year when the book was first published. It's now out in paperback. More after a break, this is FRESH AIR.
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BIANCULLI: This is FRESH AIR. Our guest is Adam Cohen, author of the book "Imbeciles: The Supreme Court, American Eugenics, And The Sterilization Of Carrie Buck," which just came out in paperback. Terry interviewed Cohen last year when the hardback was published just about a month after the death of U.S. Supreme Court Justice Antonin Scalia.
(SOUNDBITE OF ARCHIVED BROADCAST)
GROSS: Your book's publication is coinciding with a vacancy on the Supreme Court. So what is it like for you to watch this battle over this vacant Supreme Court's seat having just published this book about what you consider to be one of the worst Supreme Court decisions in American history?
COHEN: In the preface of my book, I quote one of the oldest things ever said about the law from the Code of Hammurabi, which prevailed in Babylonia 3,500 years ago, and this set of laws had a preface in which the writer said the goal of the Code of Hammurabi was to bring about the rule of righteousness in the land so that the strong should not harm the weak. And I was very moved by that because even 3,500 years ago, humanity understood that the highest goal of law should be to make sure that the strong do not harm the weak. And what's remarkable is how, in our civilized legal system in the United States, how rarely we've recognized that.
So to me, that's always the test in the law. And when the Supreme Court has gone astray, it's been in cases like Dred Scott, where the strong were allowed to say that the weak, that Dred Scott, a slave, was not allowed to sue for his own freedom, in Plessy v. Ferguson, where the strong were allowed to say that black people had to sit in, you know, the colored section of a railroad, in Korematsu v. the United States, when the government was able to say, round up all the Japanese and put them in internment camps. And we see it in things like Citizens United - just a tendency over and over again to side with the strong rather than the weak.
Well, honestly, there are few justices who embodied that, you know, misguided ideology more than Justice Scalia. And while I'm sorry for his loss and his family's loss, the vacancy does create a possibility for us to get more of the kind of court that, you know, not only would we want, but I think even in Babylonian times they recognized a court that looks out for the weak and that doesn't reflexively side with the strong.
GROSS: So let's get back to the Supreme Court decision that upheld a Virginia law allowing the forced sterilization of people considered unworthy - like, mentally unworthy to have children. What happened to Carrie Buck after that decision?
COHEN: Well, she was sterilized. And, you know, to read about it is - you know, it does really underscore what a serious operation it was. She was operated on, she had, you know, a couple weeks of what seemed like rather painful recovery from it. And then as the model of the time dictated, they could let her go because she was no longer a threat to the nation's gene pool so they let her go...
GROSS: Let her go from the colony that kept her confined.
COHEN: Yes. Yes, the colony then let her go, and they found a placement for her. She - you know, the sadness just compounds. She had very much wanted to go back to her foster family, which was raising her child who would be the only child she'd be able to have. And throughout the process, they had said that one of the great things about Carrie Buck being sterilized is she would then be free to go back to live with the Dobbs family and that the Dobbs family would happily take her back. This had been all worked out.
So of course when they are letting her go, the Dobbs family, which now has her daughter, does not want her back, you know? And it's not clear if that's because they're worried about, you know, losing control of the daughter. But - so she's not allowed to rejoin her daughter. And she is sent off basically to a series of assignments to be housekeepers for various families. And she lives her life. She eventually marries and marries again. She, of course, never had children. And, you know, one of the poignant facts that came out towards the end of her life is that, you know, no one who knew her as an adult thought that there was anything wrong with her mentally. And one of the friends who knew her at an old age home towards the end of her life said she always had her eye out for the daily newspaper, was very excited when it arrived so she could, you know, read all the news and that she used to love doing crossword puzzles. So this was the woman who was deemed too feebleminded to reproduce.
GROSS: So the 1927 Supreme Court decision that upheld a state's right to forcibly sterilize a man or a woman who was considered feebleminded and genetically unworthy to reproduce, you consider that decision one of the worst Supreme Court decisions ever. You acknowledge there's a lot of competition for that. But why do you consider this one of the worst?
COHEN: Well, you know, if you start by just looking at all the human misery that was inflicted, about 70,000 Americans were sterilized as a result of this decision. So that's an awful lot of people who wanted to have children who weren't able to have children. Also we have to factor in all of the many people who were being segregated, who were being held in these institutions for, you know, eugenic reasons because they were feebleminded, whose lives, you know, unfolded living in places like the colony rather than living in freedom.
Beyond the human effect, though, there was something just so ugly about this decision. And, you know, when you think about what we want the Supreme Court to be, what the founders wanted the Supreme Court to be, it was supposed to be our temple of justice, the place that people could go when all the other parts of our society, all the other parts of the government were not treating them right. So Carrie Buck, this poor woman who has been raped, who has been wrongly designated feebleminded, who has had her baby taken from her, who is being held as a prisoner in his horrible colony, goes to the U.S. Supreme Court. And we all know what the court should've done.
Not only did it not do it, but the contempt that, you know, just dripped from this decision - three generations of imbeciles are enough, it's better for all the world, you know, if we sterilize more of these people. It just was a level of ugliness that I'm not sure we've really seen often in the Supreme Court.
GROSS: I didn't know about this 1927 eugenics Supreme Court decision until reading your book, and I was surprised to read in your book also that this decision has never been overturned. It's still in the books. So why is it still in the books? And does it have any meaning now? Is it being used to justify forced sterilization or colonization?
COHEN: Well, the court had an opportunity to overturn it in a 1942 case challenging the Oklahoma sterilization law and they specifically chose not to. They struck down the Oklahoma law but on very narrow grounds, and the justice who wrote the decision later said, yeah, we wanted to keep Buck v. Bell in place. And it is still being used. In 2001, a sterilization was upheld by a U.S. Court of Appeals - one step below the Supreme Court - citing Buck v. Bell. So it's still there and it's still being used. And, you know, honestly, we're living in strange times now. I think we all see that every time we, you know, turn on the news or pick up the newspaper.
Could this be used to approve, to uphold bad policies that our next president or our next Congress or, you know, some state legislature enacts? Absolutely. It's a menace as long as it is the law of the land. And it is the law of the land.
GROSS: Why do you think it's important that Americans know about eugenics and this chapter of American history?
COHEN: Well, you know, it is - it was shocking to me how little-known it is, and, you know, I didn't learn it in law school. The leading constitutional law treatise - you know, which is, over 1,700 pages - you know, has half of a sentence and a footnote about it. It's just not, you know, something that people are aware of. The reason it's important is that, you know, I think that the instinct to demonize the other, to try to defeat the other, is, you know, very - you know, deeply felt in our country and no doubt other countries. You see some of it in the immigration debate going on today. I think these instincts to say that, you know, we need to stop these other people from polluting us, from changing the nature of our country, they're very real, they may be growing right now. And I think that, you know, the idea that those who don't remember the past are condemned to repeat it, it's very troubling that we don't remember this past.
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Climate goals require "radical action" from the food and beverage businesses Food Tank – Food Tank
Posted: at 11:56 am
The global food system is responsible for about one-third of human-caused greenhouse gas (GHG) emissions, with most of those emissions attributed to agriculture and land use. But food can also be an incredibly powerful solution. Because of their immense power, food and beverage companies can help support governments and civil society to achieve major climate goalsor, they can do the opposite.
Were not going to solve this by waiting for government, COP, the UN, or anyone to solve it. This is something that requires individual action, and to be frank, it requires radical action,Patrick Brown, CEO of Impossible Foods, says at a Global Landscapes Forum panel hosted by Oatly and moderated by Food Tank President Danielle Nierenberg at COP26 on November 6.
Many of these solutions lie in the animal agriculture industry. According to Brown, talking about the food system as a climate problem is like calling out liquids as a problem instead of the oil industry. The most destructive technology in human history is the use of animals to make food, he says.
Policymakers, businesses, and civil society can create new business models that support farmers, eaters, and businesses alike. Much of this action can be driven by learning whats already working. For example, while Indigenous peoples account for five percent of the global population and hold less than a quarter of the worlds land, they maintain 80 percent of the remaining biodiversity.
When we think about what we should be doing differently, its learning from many of these Indigenous practices, says Tania Eulalia Martinez Cruz, Indigenous Activist and Researcher. Policies should be designed with this context in mind, she says, accounting for the rich tradition within Indigenous food systems.
If we got rid of animal agriculture today and continued to grow plant-based products in the same way that theyre grown today, and not paying attention to [these lessons], wed still have a broken system, Ashley Allen, CSO at Oatly, adds.
Theres no doubt that consumers are demanding healthier solutions and want more information about supply chains, and meanwhile, farmers are suffering in the current food system model. Businesses have a critical role to play in driving the shift towards a more sustainable food system that leaves no one behind.
Oatly is working to bring food products carbon foodprints to the forefront of labels and conversations surrounding sustainability. Meanwhile, Apeel Foods is empowering consumers to prevent the low-hanging fruit of food waste, says Jessica Vieira, Apeels Senior Director of Sustainability.
But modernization is not the only way forward. For Louise Mabulo, Founder of the Cacao Project in the Philippines, localized solutions are more practical and economical. Food businesses can sustainably scale by finding where this local knowledge meets more modern technologies.
It doesnt mean we have to go back to pulling tractors by horses, says Allen.
Eventually, all businesses and production models will have to be sustainable: The U.N. Food and Agriculture Organization (FAO) has warned that the planet has fewer than 60 harvests left. If businesses dont invest in more sustainable practices now, they wont make any business down the line, says Mabulo.
Financial institutions are beginning to see a solid business case for investing in sustainability. Vieira speaks about a recent shift from viewing food wastea US$2.6 trillion problemnot as a tax on the system but as an untapped savings account.
But food technology solutions can only be scaled if they are appropriately adapted to each region. A food systems transition would look very different in the global north versus the global south, says Mabulo. Democratizing the distribution of these solutions means investing in Indigenous communities while ensuring theyre the ones leading the research, certifications, and education within their own communities.
If we move fast enough, is there potential for us to not just address food loss and waste, increase income opportunities by creating market access, but maybe even leapfrog the cold chain in some instances, says Vieira.
But this requires partnerships to understand producers on-the-ground needs. For example, International Finance Corporation (IFC) and Apeel are partnering in emerging markets to increase market opportunities for fruit and vegetable producers with Apeels plant-based shelf-life extension technology. Oatly is helping dairy farmers transition to crops such as oats and cashews that can be used to make plant milk, butter, cheese, and yogurt.
By forging unconventional partnerships as well as working with and building upon Indigenous knowledge systems, transformation is not only possible, its necessary, says Nierenberg.
We dont have 11 years, we have tomorrow to make these changes. Now more than ever, we cant sit back and have all talk and no action.
Click here for Food Tanks full list of events at COP26register now and tune in FREE!
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Climate goals require "radical action" from the food and beverage businesses Food Tank - Food Tank
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When it comes to coffee grounds in compost, how much is too much? Ask an expert – OregonLive
Posted: at 11:56 am
Gardening season is winding down, but you may still have some questions. For answers, turn to Ask an Expert, an online question-and-answer tool from Oregon State Universitys Extension Service. OSU Extension faculty and Master Gardeners reply to queries within two business days, usually less. To ask a question, simply go to the OSU Extension website, type it in and include the county where you live. Here are some questions asked by other gardeners. Whats yours?
Q (1 of 2): I was wondering if one could have too many coffee grounds in a compost pile?
I have a three-bin system and take in so many leaves from my neighbors yard each autumn (about 30 yard bags). This year, to help make sure I have a better balance, Im getting a 5-gallon bucket of coffee grounds from a local coffee shop each week and am adding it to each bin on a rotating basis so that every third week each section will get the grounds in addition to my kitchen waste.
I was wondering if my overall compost pH will be relatively balanced if Im mixing the grounds with this huge abundance of leaves or should I dial back on the grounds? Multnomah County
A: Interestingly, when a compost pile is composed of primarily plant matter (leaves, food waste, coffee grounds), it begins at a low pH and rises to about neutral. Low pH because the decomposition of plant materials results in the release of organic acids - initially.
When a compost pile is composed primarily of animal carcasses, manures, blood meal, it begins at a high pH and falls to about neutral. High pH because readily released nitrogen may be in the form of ammonia initially.
So the coffee idea is OK, but coffee is pretty low in nitrogen content, maybe 2-3% at best. In your situation, Id consider going to the feed store and getting a 40-pound sack of alfalfa pellets. Id sprinkle the pellets every 3-5 inches of depth in the pile of leaves. The breakdown of the alfalfa will contribute nitrogen and really get the bacteria in the piles working. Even better, if you could find a handful of red wiggler worms for each of the bins. One spring I found that I had 50 gallons of worm castings! Linda Brewer, OSU Extension soil specialist
Q: (2 of 2) I dont think I know what the range of nitrogen content is for leaves. Do you have that information readily available? 🙂
Also, my bins are full of worms, they are small and red, but I dont know if they are the official red wrigglers. Do you think they are serving a similar service and could substitute for the alfalfa pellets? Or are the worms and pellets offering two different things to the compost process?
A: To answer your questions:
Deciduous trees harvest a lot of resources from those leaves before they drop them. So, the nitrogen content of autumn leaves is essentially zero. Autumn leaves provide complex structural carbohydrates (youd say fiber if it was a human diet). Cardboard and paper are examples of structural carbohydrates. And those carbohydrates have the ability to hang on to moisture and absorb the juicier parts of kitchen scraps.
Alfalfa is valued in animal diets (and in composting) because of the nitrogen it provides. Nitrogen is an essential building block of proteins. The animals doing the work in a compost pile are bacteria think of them as little water-filled balloons made of protein. The heat in an active compost pile is the result of the metabolism of all of these bacteria, collectively. A simple definition of metabolism could be if you eat you give off heat.
If there was not enough nitrogen to support bacterial life, the work would be done by fungi. They prefer dryer conditions, and have the ability to reach out beyond their central structures and collect scarce resources like water and nitrogen. But they are far slower at the job than bacteria.
I can assure you that that you have a great supply of official red wigglers. Red wigglers are large enough to have mouths, guts, etc. They are eating and (frankly) pooping. All organisms that eat with a mouth and have a gut digest food to extract the nutrients necessary for their life functions. They extract energy by breaking carbon to carbon molecular bonds. What they dont require for their life functions, they pass through as excreta. As a result, all fecal matter contains concentrated nutrients which is why manures have been the traditional valued fertilizer source for agriculture.
Worms arent doing what the alfalfa pellets do. Worms are nutrient concentrators; alfalfa pellets are a source of nitrogen. You can do either or both. I suspect that if you can afford to do both, you will have a richer compost in a shorter period of time.
Linda Brewer, OSU Extension soil specialist
Q: What are some good resources for preparing vegetable gardens for winter? Jackson County
A: Page 5 of this publication gives a good summary of activities to do in vegetable gardens in the fall.
In addition, this website from the University of Minnesota gives some great ideas for fall vegetable garden activities.
If youre interested in growing vegetables in the fall and winter, this guide is a great resource. Danielle Knueppel, assistant professor of practice, OSU Department of Horticulture
Drained garden hoses can be stored outdoors. Oregonian file photo.
Q: Is it OK to store my drained garden hoses on my covered porch or open-sided shed? I have many due to our watering system. They take up too much space in our shop/garage. Douglas County
A: Storing hoses that have been drained on a porch or shed that is open to the outdoor temperature is fine. They will not be damaged by a freeze. After draining you can attach the ends to each other if you roll them up to make sure no insects or dirt get in them. Steve Renquist, OSU Extension horticulturist
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AstraZeneca Canada Files for Health Canada Authorization of AZD7442 for Prevention Of COVID-19 – Canada NewsWire
Posted: at 11:56 am
MISSISSAUGA, ON, Nov. 3, 2021 /CNW/ -AstraZeneca Canada has initiated a rolling review New Drug Submission with Health Canada for authorization of AZD7442, its long-acting antibody (LAAB) combination, for prevention of symptomatic COVID-19.
If granted, AZD7442 would be the first LAAB to receive Health Canada authorization for COVID-19 prevention.
"AZD7442 is the first LAAB with Phase III data demonstrating a statistically significant reduction in the risk of developing symptomatic COVID-19 compared to placebo. This is an important option, especially for vulnerable populations like those who are immune-compromised and often aren't able to mount a protective response following vaccination," said Dr. Alex Romanovschi, Vice President, Scientific Affairs, AstraZeneca Canada. "With this Health Canada filing, we are one step closer to providing an additional long-lasting option to help protect against COVID-19 alongside vaccines."
In August 2021, AstraZeneca announced high-level results from the PROVENT pre-exposure prophylaxis trial, which showed AZD7442 reduced the risk of developing symptomatic COVID-19 by 77% (95% confidence interval (CI): 46, 90), compared to placebo. Importantly, the trial population included people with co-morbidities and who may be in need of additional protection from SARS-CoV-2 infection. Greaterthan 75% of participants in PROVENT presented with co-morbidities associated with an increased risk of severe disease or a reduced immune response to vaccination. The trial accrued 25 cases of symptomatic COVID-19 at the primary analysis.AZD7442was well-tolerated.
AZD7442 was optimized using AstraZeneca's proprietary YTE half-life extension technology which more than triples the durability of its action compared to conventional antibodies.1-4
Preliminary 'in vitro' findings demonstrate that AZD7442 demonstrates broad anti-COVID activity, and in particular neutralizes recent emergent SARS-CoV-2 viral variants, including the Delta and Mu variants.5,6
About AZD7442AZD7442 is a combination of two LAABs tixagevimab (AZD8895) and cilgavimab (AZD1061) derived from B-cells donated by convalescent patients after SARS-CoV-2 virus. Discovered by Vanderbilt University Medical Center andlicensed to AstraZeneca in June 2020, the human monoclonal antibodies bind to distinct sites on the SARS-CoV-2 spike protein7 and were optimized by AstraZeneca with half-life extension and reduced Fc receptor and complement C1q binding. The half-life extension more than triples the durability of its action compared to conventional antibodies and could afford up to 12 months of protection from COVID-19 following a single administration;1-4 data from the Phase I trial show high neutralizing antibody titres for at least nine months.8 The reduced Fc receptor binding aims to minimize the risk of antibody-dependent enhancement of disease a phenomenon in which virus-specific antibodies promote, rather than inhibit, infection and/or disease.9
AZD7442 is being studied in a comprehensive clinical trial program for both prevention and treatment of COVID-19 in over 9,000 participants. In the Phase III PROVENT trial, AZD7442 reduced the risk of developing symptomatic COVID-19 by 77%, compared to placebo. The trial included 5,197 participants in a 2:1 randomization AZD7442 to placebo. The primary analysis was based on 5,172 participants who did not have SARS-CoV-2 infection at baseline. The LAAB was well tolerated, and preliminary analyses show adverse events were balanced between the placebo and AZD7442 groups.
InTACKLE,10 a Phase III mild-to-moderate COVID-19 outpatient treatment trial, AZD7442met its primary endpointdemonstrating a 50% reduction in the risk of developing severe COVID-19 or death compared to placebo in outpatients who had been symptomatic for seven days or less.
Other ongoing trials includecollaborator treatment trials in outpatient and hospitalized settings.
Data published in Naturein July 2020 showed that in preclinical experiments, the LAABs were able to block the binding of the SARS-CoV-2 virus to host cells and protect against infection in cell and animal models of disease.11
About AstraZeneca CanadaAstraZeneca is a global, innovation-driven biopharmaceutical business with a focus on the discovery, development and commercialization of primary and specialty care medicines that transform lives. Our primary focus is on four important areas of healthcare: Cardiovascular, Renal and Metabolic disease; Oncology; Respiratory & Immunology; and Rare Diseases. AstraZeneca operates in more than 100 countries and its innovative medicines are used by millions of patients worldwide. In Canada, we employ roughly 1,090 employees across the country and our headquarters are located in Mississauga, Ontario. For more information, please visit the company's website at http://www.astrazeneca.ca.
References
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Robbie GJ, et al. A novel investigational Fc-modified humanized monoclonal antibody, motavizumab-YTE, has an extended half-life in healthy adults. Antimicrobial Agents and Chemotherapy. 2013; 57 (12): 6147-53.
2.
Griffin MP, et al. Safety, tolerability, and pharmacokinetics of MEDI8897, the respiratory syncytial virus prefusion F-targeting monoclonal antibody with an extended half-life, in healthy adults. Antimicrobial Agents and Chemotherapy. 2017; 61(3): e01714-16.
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Yu XQ, et al. Safety, tolerability, and pharmacokinetics of MEDI4893, an investigational, extended-half-life, anti-staphylococcus aureus alpha-toxin human monoclonal antibody, in healthy adults. Antimicrobial Agents and Chemotherapy. 2016; 61 (1): e01020-16.
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Domachowske JB, et al. Safety, tolerability and pharmacokinetics of MEDI8897, an extended half-life single-dose respiratory syncytial virus prefusion F-targeting monoclonal antibody administered as a single dose to healthy preterm infants. ThePediatric Infectious Disease Journal.2018; 37(9): 886-892.
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Wang L et al. Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants. Science. 2021 Jul 1. doi: 10.1126/science.abh1766.
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ACTIV. National Center for Advancing Translational Sciences OpenData Portal. SARS-CoV-2 Variants & Therapeutics, All Variants Reported in vitro Therapeutic Activity. Available at: https://opendata.ncats.nih.gov/variant/activity [Last accessed: September 2021].
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Dong J, et al. Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktail. bioRxiv. 2021; doi: 10.1101/2021.01.27.428529.
8.
Loo Y-M, et al. AZD7442 demonstrates prophylactic and therapeutic efficacy in non-human primates and extended half-life in humans. medRxiv. Cold Spring Harbor Laboratory Press; 2021 [preprint] Available from: https://www.medrxiv.org/content/10.1101/2021.08.30.21262666v1.
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van Erp EA, et al. Fc-mediated antibody effector functions during respiratory syncytial virus infection and disease. Front Immunol. 2019; 10: 548.
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Clinicaltrials.gov. Phase III study of AZD7442 for treatment of COVID-19 in outpatient adults (TACKLE). Available at: https://clinicaltrials.gov/ct2/show//NCT04723394. [Last accessed: 30 June 2021].
11.
Zost SJ, et al.Potently neutralizing and protective human antibodies against SARS-CoV 2.Nature. 2020; 584: 443449.
SOURCE AstraZeneca Canada Inc.
For further information: Mary-Anne Cedrone, AstraZeneca Canada, E-mail: [emailprotected]
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Save yourself time and money by leaving the leaves: Ask an expert – OregonLive
Posted: at 11:56 am
Gardening season is winding down, but you may still have some questions. For answers, turn to Ask an Expert, an online question-and-answer tool from Oregon State Universitys Extension Service. OSU Extension faculty and Master Gardeners reply to queries within two business days, usually less. To ask a question, simply go to the OSU Extension website , type it in and include the county where you live. Here are some questions asked by other gardeners. Whats yours?
Q: Its common practice to rake up all the leaves and recycle them by placing them in the yard waste bin or blowing them into the street for pickup on trash day.
Are there any cases in which leaving leaves where they fall is a good idea? I grind up leaves (maple, not oak) and place on my garden. I leave leaves from my rhododendrons and photinia bushes on the ground as mulch.
Im trying to convince my neighbors to leave more leaves in place because most will simply disappear by spring.
What say you? Which leaf species are leavable and which are not? Benton County
A: Absolutely they are good to leave on the ground. They are the best organic mulch you dont have to buy. You are right, many leaves break down and feed the micro-organisms in the soil forming nutrients for the plants. They also suppress weeds and as a mulch hold moisture in the ground and keep the roots warmer during the winter and cooler during the summer.
Did you know that moisture in the ground during a freeze is best for your plants?
Micro-organisms are the soil life and they need nutrients all the time.The more leaves left as a mulch or broken down by your lawn mower the better.
More and more people are finding organic compost is the only thing they need for a fertilizer.That would include both greens (grass, lettuce, veggies, etc.) and browns (leaves, twigs, paper, etc.). If nothing else, have them give the leaves to you.Put them in a pile, add some greens and maybe some composted manure and make your soil for next spring. Turning the pile and keeping it moist (not hard to do now) will help it breakdown faster.
Too much moisture and the nutrients wash away so use a tarp and weight it down so it wont blow away.
Your neighbors will be able to see how well your plants do and how little money you spend. Using leaves from your property also gives you the knowledge ofwhat has been done with them in the past.Unsprayed leaves are the best.
By the way, oak leaves are OK to use around oaks and mowing them will make them breakdown faster.
The leaves also provide shelter for insects and are habitats for butterflies, moths and for frogs and toads.In a balanced eco-system, all of their needs can be met.Many of the predator insects need this shelter in order to survive the winter and come out in the spring to eat the pests that prey on your plants.
If your grass or leaves have been sprayed with chemicals, do not use them in your compost piles or spread them around any vegetable or fruit plants you may have.
That said, leaving thick piles of leaves on the lawns will kill the lawn.However, mowing the leaves and leaving a light layer is an excellent way to feed the lawn, just as mowing and leaving the grass clippings also helps feed the grass.
I hope some of these suggestions or reasons for keeping the leaves is helpful to you and I also hope you can persuade your neighbors to keep their un-developed fertilizer (the leaves). Sheryl Casteen, OSU Extension Master Gardener
ServiceberryOSU Extension Service
Q: I planted my serviceberry at the end of August, and it was doing OK for a while, but Ive noticed the leaves are turning yellow and brown, and it feels like way too many leaves and too much brown to be an issue getting established. I was wondering if there might be any obvious signs of something that Im missing here. Multnomah County
A: Congratulations on keeping your new tree alive during a very hot and dry summer. August can be a difficult time to successfully plant trees. But it is November now and all deciduous trees, such as serviceberry, begin the process of going dormant. The green chlorophyll breaks down, leaves turn yellow and the tree absorbs what it can before the leaves fall off. It is a normal part of growth for these types of trees.
In the spring, new leaves will form from the buds that survive the winter. Spring is also when you can expect white flowers to develop for a wonderful spring show. Jay Pscheidt, OSU Extension plant pathologist
Some fall color along the McKenzie River Trail in the Willamette National Forest. Oregonian file photo. Jamie Hale/The Oregonian
Q: We live in Forest Grove. This fall the trees seem to me to be much more colorful than most years. Is there any truth to this? If so, is there a plausible explanation? Washington County
A: I am in Lebanon. Last year was a great year for color and for this area, so is this year.As you may know the trees stop making chlorophyll in the fall when the temperatures dropand the days shorten.They are no longer staying green.The sugars in the trees turn the colors to yellow, orange and red and many shades in between.
However, you may have had more cold weather this year in Forest Grove changing the color of the leaves earlier and if you have not had any wind the leaves have stayed on the trees longer.Many of the maples turn to red, yellow and orange earlier than other trees.The other trees follow and most of themturn yellow or brown.
Up until this last week, we have had little or no wind. The leaves have stayed on the trees and all the trees had turned to their fall colors in our area. What a beautiful sight it was.
The recent wind/rainstorm cleaned many of the trees completely but we still have the later yellows and browns around. There are still some beautifully colored trees around, I hope you enjoy them. Sheryl Casteen, OSU Extension Master Gardener
Arborvitae hedgeOSU Extension Service
Q: We were thinking of planting a willow oak in our backyard for a shade tree. However, I am worried about the tree leaning. There is a very large arborvitae hedge on the property line (easily 35-40 feet tall. taller than our house) that can shade certain areas in the afternoon. I know willow oaks can get quite large and dont want it to grow all lopsided or lean away from the arborvitae because I dont think its realistic for the arborvitae hedge to live as long as the oak. We are trying to work with the neighboring apartment complex to have the arborvitae hedge trimmed (hasnt been done in years). Another ice storm is likely to see some damage to the plants we have planted underneath.
The arborist had estimated they maybe could take 10 feet off the trees. Do you think leaning will occur regardless? If the oak leans away from the arborvitae will it straighten up when older? The tree is going to be planted on the southwest part of our yard and would still get mostly full sun (and be easily 25-plus feet away from the arborvitae) but it would be shaded earlier in the day than the other trees more on the southeast side of our property. The arborvitae is also sort of downhill from the potential oak (since we live in a tiered neighborhood), so root competition with arborvitae Im not as concerned about. Multnomah County
A: I would not recommend topping the arborvitae hedge. It just wont look as good moving forward.They regrow slowly. Damaged branches should be cut back to the base.
Your newly planted oak tree might lean a bit toward the sun if the hedge is to the south of where you plant it. Use tree stakes in the first year to make sure it grows straight. After that, use pruning methods to select a central leader that points a touch away from the hedge (north side of the tree). Prune the tree to look like figure 5 in this publication. Weston Miller, OSU Extension horticulturist
Q: How do I keep the neighborhood mask bandit from enjoying all my grapes? Multnomah County
A: The first thing to make sure of is that you are not attracting the raccoons to other food sources like trash, compost or pet food. Raccoons prefer grapes so it may be a challengeto keep them totally blocked off once they become habituated. There are a few things you can do to keep them from reaping the whole harvest though. Grapes generally need most protection when they are almost ripe. Before they are ripe, the tannins keep most critters from eating them, so this doesnt need to be a year-round effort, unless you have deer hanging around.
Motion-activated lights, noise devices or sprinklers can help scare them away, andeven scents like coyote urine can keep them from being habituated. Take care not to have the sprinkler directly spraying the plants, as this can create amildew or botrytis(fungus)problem.As a last resort, you could set up a temporaryelectric fence around the vines, which is generally effective against most critters, so long as they cant climb around it. Thomas Stokely, OSU Extension forestry and wildlife specialist
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Would you want to live beyond 150?, Opinion News & Top Stories – The Straits Times
Posted: at 11:56 am
(FINANCIAL TIMES) - The three teenagers called it the Gilgamesh project, after the epic poem from ancient Mesopotamia in which the eponymous king searches for the secret of eternal life. Nearly 40 years ago, growing up in Germany, Dr Steve Horvath and his twin brother Markus and their friend Jrg Zimmerman pledged to dedicate their careers to extending human lifespans. "I've always felt that human life is too short," says Steve, now 54 and a geneticist at the University of California, Los Angeles.
Markus became a psychiatrist and Jrg a researcher into artificial intelligence. Steve stayed truest to the cause, developing a technique to measure the biological age of cells. The Horvath clock, a widely used biomarker of ageing, is one of a series of discoveries over the past two decades that are invigorating the science of life extension.
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