Daily Archives: August 9, 2021

Black Hat security conference returns to Las Vegas complete with hacks to quiet the hotel guest from hell – The Register

Posted: August 9, 2021 at 9:01 am

In Brief After a year off due to a certain virus, the Black Hat and DEF CON security conferences returned to Las Vegas last week, just in time for the US government's attempts to foster more collaboration across the infosec industry.

The newly appointed Security Director of the Cybersecurity and Infrastructure Agency Jen Easterly took to the virtual Black Hat stage last week (although there was a limited and well-spaced physical conference this year) and announced the Joint Cyber Defense Collaborative (JCDC), which she claimed would be a true public/private partnership to try to lock down security incidents by sharing data and skills.

Microsoft, AWS, Google and several US telcos have signed up, but Easterly's keynote was particularly aimed at bringing in independent talent. Among the suggestions were increasing public sector salaries and taking a more flexible approach to hiring.

DHS Secretary Alejandro Mayorkas also gave a keynote speech along the same lines, saying his agency stood ready to do its bit.

"We're really hard at work and we have no illusions about the road ahead," he said. "There is nothing simple about the cybersecurity challenges we face, and we need your help to get this right. We need your expertise to inform our policies and the future of our critical mission."

We've all had the hotel trip where someone's being too noisy. When a fellow traveler in a capsule hotel got on his nerves, a security consultant for Lexfo named Kyasup decided to hit back.

The hotel allowed guests to control aspects of their room using an iPod Touch with Bluetooth and Wi-Fi. Kyasup found [PDF] that the iPod connected to a Nasnos CS8700 router. By chaining together six vulnerabilities and forcing a reboot of the iPod touch, Kyasup found he could control any capsule in the hotel.

Kyasup had asked one guest, called Bob for anonymity, if he could be quieter at night, since the person was prone to loud 2AM phone calls. After repeated unsuccessful attempts to sort this out, Kyasup simply programmed the man's bed to convert into a couch and back again and flashed the room lights every two hours.

He then went to the hotel's management team, who were surprisingly nice about it, and fixed the issue. The moral of the story? Politeness is important.

Web app scanner Punkspider has been controversial since its release in 2013, with critics saying it can too easily be abused.

The project went dark in 2015, but now it's back, say its creators, and it's nothing for folks to worry about. A presentation at DEF CON saw Alejandro Caceres, director of computer network exploitation at QOMPLX, and self-described hacker Jason Hopper, explaining.

"We got banned more than a 15-year-old with a fake ID trying to get into a bar. It became a pain and hardly sustainable without a lot of investment in time and money. Each time we got banned it meant thousands of dollars and countless hours moving sh** around," they said.

"Now we've solved our problems and completely re-engineered and expanded the system."

The proof of that pudding will be in the eating, however, and the team may find itself shut down again. Many fear that the tool will be abused again not just to expose vulnerabilities, but to exploit some as well. You can see the full talk here.

One disturbing talk [PDF] at Black Hat this year was from former NSA instruction specialist David Evenden, now running security shop StandardUser.

Evenden recounted how he and others were wooed by intelligence agencies around the world to work with a group called CyberPoint in the United Arab Emirates on a scheme named Project Raven. The work was supposed to be intelligence gathering and defensive security work, but Evenden said he was increasingly being asked to pull in more harmful data.

Evenden and others were being asked to spy on journalists, members of the local royal families, and he even found some of Michelle Obama's emails. Despite the generous tax-free salary he, and some others, decided to get out of the country while they still could.

Evenden warned that you should never lodge your passport with an employer and always have enough cash and a plan to get out if something looks too good to be true and to check a potential employer's history carefully.

Jeff Moss, AKA Dark Tangent and the man who founded the conferences, offered a sobering warning at the start of the show. He said the industry has lost good people this year and COVID-19 will be around for a while, it seems.

Reports on the ground suggest the conferences have been very sparsely attended certainly nothing like the mad crush of tens of thousands of visitors that's normal for the show. Most attendees wore masks, but more than a few maskless wandered about.

Las Vegas already has a big COVID problem, and events like this can act as superspreader events, as this hack found out to his cost at the RSA Conference last year. Let's be careful out there, folks.

See original here:

Black Hat security conference returns to Las Vegas complete with hacks to quiet the hotel guest from hell - The Register

Posted in Boca Chica Texas | Comments Off on Black Hat security conference returns to Las Vegas complete with hacks to quiet the hotel guest from hell – The Register

SpaceX, Planet ink deal to launch Earth-imaging satellites through 2025 – Space.com

Posted: at 9:01 am

Planet has signed another contract with SpaceX, locking it in as the 'go-to launch provider' for the Earth-imaging company through 2025.

San Francisco-based Planet operates the world's largest fleet of Earth-observation satellites, most of which are tiny but capable cubesats known as Doves (or, more recently, SuperDoves). SpaceX Falcon 9 rockets have launched 83 Planet satellites on seven missions to date, and the new deal ensures that number will grow.

"I'm excited to continue our partnership with SpaceX," Planet co-founder and CEO Will Marshall said in a statement today (Aug. 5). "We've had seven launches to date. But more than that, together we've pioneered rapid planning, manufacturing and launch of satellites that only Planet and SpaceX could together have achieved."

Related: Planet satellites' views of Earth (photos)

Today's statement doesn't specify the number of planned launches or the value of the contract. It describes the deal as a "multi-year, multi-launch agreement with SpaceX, solidifying them as our go-to-launch provider through the end of 2025."

Planet spacecraft will piggyback as "rideshare" payloads on Falcon 9 rockets, as they have done in the past. The first planned launch under the new agreement is scheduled for this December, when 44 SuperDoves will lift off on SpaceX's Transporter-3 mission.

Planet satellites have launched atop a number of rockets to date, including India's Polar Satellite Launch Vehicle and Rocket Lab's Electron (which gives small satellites dedicated rides to space). Planet will maintain such diversity in the future despite the new SpaceX deal, company representatives said.

"Moving forward, we will continue to operate with a variety of launch providers to ensure that launch needs can still be met in the event of unavailabilities of specific providers," Planet representatives wrote in the same statement. "By engaging with a diversified manifest, Planet can find launches to the right orbit in the right time frame for each evolving satellite project."

For example, Planet recently signed a deal with Bay Area startup Astra for a "multilaunch mission" in 2022. Astra has not yet launched any satellites to orbit but will attempt to do so on a mission for the U.S. Space Force later this month.

Mike Wall is the author of "Out There" (Grand Central Publishing, 2018; illustrated by Karl Tate), a book about the search for alien life. Follow him on Twitter @michaeldwall. Follow us on Twitter @Spacedotcom or Facebook.

Originally posted here:

SpaceX, Planet ink deal to launch Earth-imaging satellites through 2025 - Space.com

Posted in Spacex | Comments Off on SpaceX, Planet ink deal to launch Earth-imaging satellites through 2025 – Space.com

Why Elon Musks Starlink has set up a satellite base on a tiny island in the Irish Sea – CNBC

Posted: at 9:01 am

SpaceX owner and Tesla CEO Elon Musk poses as he arrives on the red carpet for the Axel Springer Awards ceremony, in Berlin, on December 1, 2020.

Britta Pedersen | AFP | Getty Images

LONDON Starlink, the space internet service created in 2015 by Elon Musk's space transportation firm, SpaceX, has set up a "ground station" on a tiny self-governing island in the Irish Sea to help it beam internet from satellites in low-Earth orbit to homes and offices.

Starlink's Isle of Man ground station, first reported by The Telegraph late last month, can be seen on the Starlink.sx website.

The government of the Isle of Man said Starlink has been working with local communications provider Bluewave, adding that the pair have together licensed some of the island's available spectrum.

Bluewave has a ground station just outside the capital of Douglas that can be seen on Google Maps. It acquired the site last year from SES Satellite Leasing. SES pulled out of the Isle of Man last summer.

The site boasts between four and eight radomes, according to a local source who works in the satellite industry that asked to remain anonymous as they're not permitted to discuss the matter. These are structural, weatherproof enclosures that protect a radar antenna, which sends and receives data transmissions.

"There is a nearly new vacant base station array here linked directly into data centers," said another source who works in the Isle of Man's tech industry, who asked to remain anonymous as they're not directly involved with the Starlink project. The source added that it has "an excellent horizon scan because being surrounded by sea it means there is nothing in the way."

Measuring 32 miles long and 13 miles wide, the Isle of Man is a British Crown dependency that sits in the middle of the Irish Sea roughly equidistant from England, Scotland, Ireland and Wales. Starlink already has bases in Buckinghamshire and Cornwall in England, and the Isle of Man base will enable the company to provide blanket internet coverage across Britain.

The island's location, spectrum and existing satellite infrastructure have all contributed to Starlink's decision, according to the two CNBC sources.

The first source, who received a Starlink kit in May, said the island has a "very efficient" telecoms regulator that's fast to issue relatively cheap licenses.

"Then of course, the Isle of Man is a low tax jurisdiction so [there is] very little overhead," they added. "Plus the nation has an adequacy agreement with the EU for GDPR compliance. All this makes the island a good place for satellite or data related services." GDPR is a set of data protection and privacy regulations introduced by the European Union in May 2018.

The island also has its own spectrum bands that are less busy than those used in the U.K.; the Isle of Man has just 85,000 inhabitants whereas the U.K. has around 70 million.

The Isle of Man Communications and Utilities Regulatory Authority confirmed to CNBC on Thursday that Starlink and Bluewave have been granted a license for "provision of services and location of associated equipment on the island."

A spokesperson for the island's Department for Enterprise told CNBC: "This is very exciting and positive news for the Island which will enable the deployment of satellite broadband service on-Island and further afield."

They added: "Locally, the licensing of available spectrum will provide more choice for local consumers and potential for further jobs within the Island's telecoms sector."

SpaceX did not immediately respond to a CNBC request for comment, while Bluewave declined to comment.

Starlink ultimately wants to provide the world with faster internet, starting by improving internet access in parts of the world that aren't currently served by broadband providers.

It allows people to connect to the internet via a satellite dish that is placed on or near a person's property. The internet is beamed down to the dish via a network of Starlink satellites that have been put into orbit by SpaceX and ground stations.

The company has said it plans to spend $10 billion putting 12,000 small satellites into low-Earth orbit that can beam high-speed, low-latency internet to the ground. It has launched 1,700 so far and the service is being used by 90,000 customers in 12 countries.

"You can assume they'll need lots of ground stations, in lots of places, to ensure uninterrupted coverage," Craig Moffett, an analyst at research firm MoffettNathanson, told CNBC.

"The satellites aren't yet equipped with fiber interlinks, so for now, they need to be in constant contact with the ground. That requires a tremendous number of ground stations," Moffett added.

Read the original here:

Why Elon Musks Starlink has set up a satellite base on a tiny island in the Irish Sea - CNBC

Posted in Spacex | Comments Off on Why Elon Musks Starlink has set up a satellite base on a tiny island in the Irish Sea – CNBC

SpaceX to launch billboard satellite that plays ads and hopes people dont do something inappropriate – The Independent

Posted: at 9:01 am

Elon Musks SpaceX will put a huge advertising satellite in the sky where companies can display logos and other promoted content.

The space company is working with a Canadian startup Geometric Energy Corporation (GEC) to launch the satellite on a Falcon 9 rocket, which will release the advertising platform before the rocket reaches the moon.

Samuel Reid, CEO and co-founder of GEC, told Business Insider that the satellite would be released in 2022. People and companies would buy tokens to locate and design a pixel on the screen.

Five tokens affecting the pixels are purchasable: Beta and Rho for the adverts placement on the screen, Gamma and Kappa for the colour and brightness, and XI for its duration. These tokens will be purchasable via cryptocurrencies.

"Im trying to achieve something that can democratize access to space and allow for decentralized participation," Mr Reid said. "Hopefully, people dont waste money on something inappropriate, insulting or offensive.

"There might be companies which want to depict their logo ... or it might end up being a bit more personal and artistic. Maybe Coca-Cola and Pepsi will fight over their logo and reclaim over each other, he said.

It is currently unclear how large the ads will be, how many ads will be shown at any one time, the environmental impact of bright advertising on local flora and fauna, and the energy use of the satellite. Neither SpaceX nor GEC responded to The Independents request for comment before time of publication.

GEC is also the group behind the satellite Doge-1, which Mr Musk said would be the first crypto in space and the first meme in space.

The satellite will "obtain lunar-spatial intelligence from sensors and cameras", according to CNN. "This is not a joke," Reid said, but refused to comment further.

Dogecoin has proven to be a fast, reliable, and cryptographically secure digital currency that operates when traditional banks cannot and is sophisticated enough to finance a commercial Moon mission in full," a press release sent in May 2021 read.

"It has been chosen as the unit of account for all lunar business between SpaceX and Geometric Energy Corporation and sets precedent for future missions to the Moon and Mars."

Since then, however, Elon Musks tweets generally seen as market-movers in the crypto space have failed to affect dogecoins performance.

Read the original:

SpaceX to launch billboard satellite that plays ads and hopes people dont do something inappropriate - The Independent

Posted in Spacex | Comments Off on SpaceX to launch billboard satellite that plays ads and hopes people dont do something inappropriate – The Independent

Inside the SpaceX Crew Dragon: Here’s How the Inspiration4 Crew Will Fly to Space – TIME

Posted: at 9:01 am

Heres how you fly a SpaceX Crew Dragon spacecraft: Climb aboard; strap yourself in; close the hatch; fly to space. The Dragon takes care of everything, so relax and enjoy the rideunless, of course, something goes wrong, and in space, something can always go wrong.

So heres how you prepare for that possibility: Spend months of 60-hour weeks in classrooms and simulators; master hundreds of pages of technical specs and procedures; learn the workings of dozens of systems and subsystems aboard the spacecraft; train for emergencies ranging from communications blackouts to navigation failures to on-board fires; and, not for nothing, spend a little time in a centrifuge and an altitude chamber, practicing for the g-forces youre going to have to endure and the possibility of depressurization.

Theres north of 60 procedures that range from normal contingency to emergency, says Jared Isaacman, the CEO of Shift4 Payments, an online payment service, who will be commanding the Inspiration4 mission in September, spending three days in orbit with three other civilian astronauts. In a multi-day mission there is a lot of time for a lot of things to go wrong. (TIME Studios is producing a documentary series on the Inspiration4 mission.)

Practicing for those eventualities aboard a Dragon requires a whole new kind of training, because by any measure, the new ship is not your daddys spacecraft. NASAs old Mercury, Gemini and Apollo capsules were very much designed with an airplane cockpit in mind. Their sheet metal instrument panels were studded with hundreds of switches, dials, lights and analog gauges. Their simple on-board computers were controlled by a mechanical keyboard. The commander flew those ships the same way youd fly a planewith a control stick determining velocity, attitude, altitude and direction.

The Dragons designers swept all of that away, replacing everythingincluding the control stickwith three large touch screens facing four side-by-side seats. Each screen is capable of calling up as many as 10 sets of displays, allowing the crew to focus on a particular set of systemsguidance, environmental, electrical, and more.

You have an overall systems page on the screen, and then you can drill down into individual pages as well, says Doug Hurley, the commander of the first crewed SpaceX mission, which launched in May of 2020. Theres a total of 25 to 30 individual pages, and SpaceX may have added some more since my flight. With any aircraft or spacecraft, you always iterate because it makes sense and its easy and will help the crew.

The seats in the Crew Dragon spacecraft are reconfigurable, allowing it to carry up to seven peoplethough four is typical for a NASA mission. Three large touchscreens replace the traditional instrument panel.

Courtesy SpaceX

Ideally, the spacecraft helps the astronauts so much that they have virtually nothing to do, with the ship operating entirely autonomously. And if the automation doesnt take care of a problem, then the ground is your next layer of defense, says Hurley, referencing SpaceX ground controllers who can problem-solve and issue commands to the spacecraft from the comfort of mission control. Only if the Dragon fails to look after itself and the ground staffers cant solve the problem would the astronauts take over.

Thats the case too when it comes to the most critical aspect of commanding the spacecraft: flying it. The Dragon features a full-time autopilot program, requiring no astronaut intervention. On Hurleys flight, he took over in the final stages of the spacecrafts approach to the International Space Station, steering the ship in all axes, flying above, below and to the left and right of the station. But the purpose of that exercise was just to prove that the manual systems worked.

In space youve got to trust and verify, Hurley says. But theres no plans to do any more manual flying, unless theres a need for it from a systems failure kind of scenario.

Those failures do occur, and learning to fly the Dragon by hand can take some doing. Stripping out the control stick and replacing it with buttons on a touch screen may make for a more elegant spacecraft, but it also eliminates the most important physical connection a pilot has to their vehicle. Pilots using a stick never have to look at it because they operate by feel, but thats impossible with a touch screen that offers nothing by way of tactile response. When youre flying off soft keys on a touch screen its a totally different feel, and a lot of muscle memory is lost, says Isaacman, who is a licensed jet pilot and knows a thing or two about stick-and-rudder skills. There is that delay when you look at the screen and input a command before its executed, versus something instantaneous when you move the stick.

The Crew Dragon spacecraft before being mated to its Falcon 9 rocket (left); the Falcon's second stage is disposable, and the first stage returns to Earth, landing on a barge, to be refitted and reused.

Courtesy SpaceX/NASA

Then too, there are the kinds of emergencies that not only require on-site human intervention, but require it to be executed immediatelyand perfectly. Fires can and do break out aboard spacecraft; crew members on Russias Mir space station had to battle a blaze in 1997 when a fuel canister ignited. The biggest risk aboard Dragon is a fire caused by a battery overheating, and there are a lot of batteries aboard the shipnot only the spacecrafts own, but those that power the tablets, cameras and smartphones the crew members will carry.

There is also the risk of a spacecraft depressurization, requiring the crew to look for the breach, try to seal it off and scramble into their suits at the same time. A launch emergency may happen tooif, say, the second stage of the Falcon 9 rocket that carries the ship to space fails to separate from the Dragon and the commander has to manually execute the separation maneuver. The Dragons guidance system is also subject to failure, potentially causing the ships solar panels to slip out of alignment with the sun and requiring human intervention to set things right.

Finally, there are the overall risks raised by the simple number of days the Inspiration4 crew will spend in orbit. Crews heading for the space station fly there directly and are usually aboard within a day or so of launching. The Inspiration4 crew will be in orbit for three days, flying independently, without the security the giant station providesthe longest a U.S. space a U.S. crew has been aloft in a vehicle other than the station since the last shuttle stood down in 2011. Every day spent on their own is another day during which something can go wrong.

The Crew Dragon spacecraft and the Falcon 9 rocket a few days before the launch of Crew-1 Mission in Nov. 2020.

Courtesy SpaceX

Ideally, nothing goes wrong on any given missionand on the three crewed flights SpaceXs Crew Dragon has flown so far, the ideal has been the real. But space remains, ever and always, a dangerous place to go. Its for the Dragon designers to remove the riskand even the workfrom the equation. Its for the crew to be prepared if that equation does not add up.

I dont know that theres ever been a human spaceflight mission that did not have some anomaly, says Isaacman. People are telling us were making good progress. I think weve definitely arrived at the point where were ready and this is going to be a well-executed mission.

For your security, we've sent a confirmation email to the address you entered. Click the link to confirm your subscription and begin receiving our newsletters. If you don't get the confirmation within 10 minutes, please check your spam folder.

Write to Jeffrey Kluger at jeffrey.kluger@time.com.

Read the original post:

Inside the SpaceX Crew Dragon: Here's How the Inspiration4 Crew Will Fly to Space - TIME

Posted in Spacex | Comments Off on Inside the SpaceX Crew Dragon: Here’s How the Inspiration4 Crew Will Fly to Space – TIME

SpaceX’s first all-civilian launch next month will be chronicled in a Netflix documentary – Business Insider

Posted: at 9:01 am

Netflix is giving viewers a behind-the-scenes look at the historic launch of SpaceX's Inspiration4 mission in a brand new documentary series.

"Countdown: Inspiration Mission to Space" will be released in five parts. The first four episodes will premiere on September 6 and 13, with the rest of the series available September 14, 1 5, and 16 surrounding the launch day from Kennedy Space Center in Florida.

Unlike Blue Origin and Virgin Galactic's spaceflights, which only touched the edge of space and returned to Earth minutes later, Inspiration will orbit the Earth for three days to raise funds and awareness for St. Jude Children's Hospital.

There will be four passengers on board the flight, including billionaire Jared Isaacman, the 38-year-old founder and CEO of Shift4 Payments, who will Lead and Command the craft, according to a press release. Hayley Arceneaux, a 29-year-old physician assistant at St. Jude and pediatric cancer survivor, will serve as the mission's Chief Medical Officer.

Dr. Sian Proctor, a 51-year-old professor of geosciences and two-time NASA astronaut candidate who long dreamed of going to space, will serve as pilot, and Chris Sembroski, a 41-year-old, former member of the U.S. Air Force who served in Iraq and now works as a Lockheed Martin engineer, will serve as mission specialist.

"The crew was selected to represent the four pillars of the mission: Leadership, Hope, Prosperity, and Generosity," Netflix said in a press release.

The documentary series will be directed and executive produced by Jason Hehir, the director of the Michael Jordan and Chicago Bulls documentary "The Last Dance" on Netflix.

See the rest here:

SpaceX's first all-civilian launch next month will be chronicled in a Netflix documentary - Business Insider

Posted in Spacex | Comments Off on SpaceX’s first all-civilian launch next month will be chronicled in a Netflix documentary – Business Insider

Curiosity, SpaceX, and Time Crystals: this week in science news – TechRadar

Posted: at 9:01 am

This week was a pretty eventful one in science news, full of record-breaking rockets, a major anniversary for a remarkably vain robot on Mars (we kid, we kid. We love you Curiosity!), and Google claiming that it used its quantum computer to flagrantly violate one of the basic principles of physics.

Boeing unfortunately suffered another frustrating setback with its Starliner capsule, further delaying its second attempt at reaching the International Space Station. Speaking of which, ISS astronauts bid farewell to the Russian-made Pirs module as it safely burned up in the Earth's atmosphere and were kind enough to record this human "shooting star" for us critters down below.

Read on to learn more about all the exiting news you might have missed this week in the world of science.

NASA's highly photogenic Curiosity rover celebrated its ninth year on the red planet this week, sending out a trademark selfie in celebration.

The intrepid rover touched down in Gale Crater on the Martian surface in the late evening hours of August 5, 2012 (NASA's Jet Propulsion Laboratory is in California, so the landing occurred on August 6, 2012 EDT). Since then, it has travelled more than a dozen miles across the Martian surface, even ascending nearly half a kilometer up the slope of Mount Sharp in the crater's center, making science with every turn of its many wheels. Here's to another year of science and many more to come!

As SpaceX prepares to return astronauts to the Moon in 2024, it is assembling some of the most advanced spacefaring vessels ever, including the largest rocket ever assembled. This week, SpaceX tested the stacking and mating of its Starship spacecraft with the Super Heavy rocket booster that will help carry it into its first orbital flight later this year. The two combined for a total height of 395 feet, beating out the previous record-holder, the Apollo program's Saturn V rocket, which stands at 363 feet.

SpaceX rival Boeing, meanwhile, suffered another frustrating setback this week in its efforts to get it's Starliner capsule off the ground and docked with the International Space Station (ISS). After last week's launch had to be postponed when an accidental misfire of a docked Russian capsule rotated the ISS and altered its trajectory it's fine now...we hope? Boeing and United Launch Alliance detected an unexpected "valve position indication" during a pre-launch check, and the launch was scrubbed until engineers can track down the problem. This puts Boeing even further behind SpaceX, something that's gotta sting for the venerable spaceflight pioneer.

Astronauts aboard the International Space Station recorded the fiery end of the Russian-made Pirs module as it (safely) burned up in Earth's atmosphere.

The timelapse video shows the module turning into a "shooting star" of sorts, a fitting send off after its service in pursuit of science and discovery.

Finally, this week saw the science world trying to wrap their brains around a paper published by Google researchers late last week that claims to show its quantum computer, Sycamore, created a scalable "time crystal" using qubits that complete violate the second law of thermodynamics and the principle of time translation symmetry. What this development means is still unclear, since something like this isn't supposed to ever happen, so we'll have to wait for peer review to do its thing and confirm results from Google's scientists. If they do, maybe Sycamore can show us how to divide by zero, while it's at it.

Excerpt from:

Curiosity, SpaceX, and Time Crystals: this week in science news - TechRadar

Posted in Spacex | Comments Off on Curiosity, SpaceX, and Time Crystals: this week in science news – TechRadar

SpaceX is Breaking Records with This Newly Assembled Rocket Ship in Texas – ktemnews.com

Posted: at 9:01 am

Historic Moments in Texas

August 6th, we got a live view of something very historical happening. Livestreams of what's going down at theSpaceXStarbase facility in South Texas aired as people around the globe watched in anticipation.

The city of Boca Chica plays host to a SpaceX facility that is breaking records and making history happen. Engineers and workers completed the stacking of their massive SpaceX Starship.

The Starship stands alone at 165 feet, and the Super Heavy rocket adds another 230 feet making the massive vehicle just about 400 feet tall, make it the BIGGEST rocket ever assembled.

The bottom part of the rocket is the Super Heavy rocket. This piece is what is going to get the rocket soaring into space. It contains 29 raptor engines. That is a whole lot of power, which is necessary for a rocket that plans to reach the moon and Mars in its very first orbital test flight.

The Starship is the second part of the rocket. It sits on top of the Super Heavy rocket and is what will eventually carry cargo and passengers.

All of this went down Friday, August 6th, and Texas got to get in on this historic assembly. The record-breaking rocketship was assembled in the great state of Texas.

While the ship was assembled on August 6th, there is speculation that Elon Musk was aiming for the previous day, August 5th. On his personal Twitter page, Musk tweeted, "Winds are too high today. Looks like wind speed will be low enough to stack early tomorrow morning."

While the Starship and Super Heavy rocket assembly are complete, this massive rocket will not be launched just yet. SpaceX still has a couple of measurements they need to go through to get this rocket fully finished and ready.

According to MSN, the Super Heavy rocket "must pass several pressurization and engine tests before lifting off." Aside from that, "SpaceX is also waiting on anenvironmental review of Starship's launch operationsbeing performed by the U.S. Federal Aviation Administration."

Women have left marks on everything from entertainment and music to space exploration, athletics, and technology. Each passing year and new milestone makes it clear both how recent this history-making is in relation to the rest of the country, as well as how far we still need to go. The resulting timeline shows that women are constantly making history worthy of best-selling biographies and classroom textbooks; someone just needs to write about them.

Scroll through to find out when women in the U.S. and around the world won rights, the names of women who shattered the glass ceiling, and which country's women banded together to end a civil war.

LOOK: 100 years of American military history

See the rest here:

SpaceX is Breaking Records with This Newly Assembled Rocket Ship in Texas - ktemnews.com

Posted in Spacex | Comments Off on SpaceX is Breaking Records with This Newly Assembled Rocket Ship in Texas – ktemnews.com

The Secret History of Corn And Its Jumping Genes Revealed in Its Genome – SciTechDaily

Posted: at 9:00 am

This ear of corn was grown and analyzed by Nobel Prize-winning Cold Spring Harbor Laboratory (CSHL) geneticist Barbara McClintock decades ago. From her observations, she surmised that parts of the corn genome jumped from one location to another, generating a great deal of genetic diversityin this case many different colors of kernels. CSHL researchers expanded on her work by sequencing the genomes of multiple corn strains, mapping even the mobile portions of the genome. Credit: CSHL Library & Archives

Humans adapt through language and culture, passing down knowledge from one generation to the next. Corn plants cant talk, so they solve the problem of adaptability in a different way: they use jumping genes to shuffle the genetic deck over generations. Jumping genesnow called transposonswere discovered by Nobel Prize-winning Cold Spring Harbor Laboratory (CSHL) geneticistBarbara McClintockin the 1940s. Decades later, CSHL scientists are still expanding on her work.Doreen Ware, a CSHL adjunct professor and research scientist at the US Department of Agriculture (USDA) and her colleagues, published genome sequences from 26 different strains of corn in the journalScience. The genomes describe a large portion of the genetic diversity found inmodern corn plants, including transposons and genes that regulate desired crop traits.

CSHL Adjunct Professor and USDA research scientist Doreen Ware in a cornfield at CSHLs Uplands Farm. Credit: Ware lab/CSHL

Corn has been bred to grow in various climates of the world, from temperate to tropical, and from highlands to lowlands. Ware says:

Humans have brains. Our main adaptive component is our ability to transfer culture and knowledge, right? And thats how we deal with our environment. A plants strategy is to have a fluid genome. They have a very intimate relationship with these transposons, where they use them to bring in new genetic diversity so that they can deal with these events because they cant run away. Theyre not going to go into the house, and theyre not going to move water to them.

Ware and her colleagues, including CSHL Professor & HHMI InvestigatorRob Martienssenand CSHL ProfessorW. Richard McCombie, mapped thefirst corn genomein 2009; they have been filling in gaps ever since. Like a continental landscape, genomic maps have areas that are full of features (like well-mapped cities), whereas others are more like deserts (vast and uncharted). With recent techniques, the team of scientists charted difficult stretches of the genome, even the deserts. These complete genomes allow researchers to locate and study bothimportant crop genesand the nearby regions that regulate their use. Ware notes, we had little access to the regulatory architecture of corn before.

The new collection reveals how the corn genome was shuffled over time. Ware says:

These genomes provide us a footprint of that life history. Different strains have experienced different environments. For example, some came from tropical environments, others experienced particular diseases, and all those selective pressures leave a footprint of that history.

Corn is one of the most common agricultural staples in the world, with more than366 million metric tonsgrown in the US from 2018 to 2019. Equipped with more detailed maps of the corn genome, scientists have a head start in developing crops for a rapidly changing climate. Ware explains, The Midwest is not going to have the same temperature profile twenty years from now. The genomes provide broader insights into corn genetics, and this, in turn, can be used to start optimizing corn to grow in future environments.

Reference: De novo assembly, annotation, and comparative analysis of 26 diverse maize genomes by Matthew B. Hufford, Arun S. Seetharam, Margaret R. Woodhouse, Kapeel M. Chougule, Shujun Ou, Jianing Liu, William A. Ricci, Tingting Guo, Andrew Olson, Yinjie Qiu, Rafael Della Coletta, Silas Tittes, Asher I. Hudson, Alexandre P. Marand, Sharon Wei, Zhenyuan Lu, Bo Wang, Marcela K. Tello-Ruiz, Rebecca D. Piri, Na Wang, Dong won Kim, Yibing Zeng, Christine H. OConnor, Xianran Li, Amanda M. Gilbert, Erin Baggs, Ksenia V. Krasileva, John L. Portwood II, Ethalinda K. S. Cannon, Carson M. Andorf, Nancy Manchanda, Samantha J. Snodgrass, David E. Hufnagel, Qiuhan Jiang, Sarah Pedersen, Michael L. Syring, David A. Kudrna, Victor Llaca, Kevin Fengler, Robert J. Schmitz, Jeffrey Ross-Ibarra, Jianming Yu, Jonathan I. Gent, Candice N. Hirsch, Doreen Ware and R. Kelly Dawe, 6 August 2021, Science.DOI: 10.1126/science.abg5289

The project was a multi-institutional effort with researchers at CSHL, USDA, University of Georgia, Iowa State University, University of Minnesota, and Corteva Agriscience. The new collection of genomes is available online athttp://maize-pangenome.gramene.org/.

Go here to read the rest:
The Secret History of Corn And Its Jumping Genes Revealed in Its Genome - SciTechDaily

Posted in Genome | Comments Off on The Secret History of Corn And Its Jumping Genes Revealed in Its Genome – SciTechDaily

Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration – Nature.com

Posted: at 9:00 am

Hotez, P. J. et al. The Global Burden of Disease Study 2010: interpretation and implications for the neglected tropical diseases. PLoS Negl. Trop. Dis. 8, e2865 (2014).

World Health Organization. Prevention and Control of Schistosomiasis and Soil-transmitted Helminthiasis: Report of a WHO Expert Committee (World Health Organization, 2002).

Montresor, A., Engels, D., Ramsan, M., Foum, A. & Savioli, L. Field test of the dose pole for praziquantel in Zanzibar. Trans. R. Soc. Trop. Med. Hyg. 96, 323324 (2002).

CAS PubMed Article PubMed Central Google Scholar

World Health Organization. Helminth Control in School-aged Children: A Guide for Managers of Control Programmes (World Health Organisation, 2006).

World Health Organization. Schistosomiasis and soil-transmitted helminthiases: numbers of people treated in 2019. Wkly. Epidemiol. Rec. 95, 629640 (2020).

Google Scholar

Kabatereine, N. B. et al. Impact of a national helminth control programme on infection and morbidity in Ugandan schoolchildren. Bull. World Health Organ 85, 9199 (2007).

PubMed PubMed Central Article Google Scholar

Bronzan, R. N. et al. Impact of community-based integrated mass drug administration on schistosomiasis and soil-transmitted helminth prevalence in Togo. PLoS Negl. Trop. Dis. 12, e0006551 (2018).

PubMed PubMed Central Article Google Scholar

Deol, A. K. et al. Schistosomiasisassessing progress toward the 2020 and 2025 global goals. N. Engl. J. Med. 381, 25192528 (2019).

World Health Organization. Accelerating work to overcome the global impact of neglected tropical diseases: a roadmap for implementation. https://apps.who.int/iris/bitstream/handle/10665/338712/WHO-HTM-NTD-2012.5-eng.pdf (2012).

World Health Organization. A road map for neglected tropical diseases 20212030. https://www.who.int/neglected_diseases/Ending-the-neglect-to-attain-the-SDGsNTD-Roadmap.pdf (2020).

Mutuku, M. W. et al. A search for snail-related answers to explain differences in response of Schistosoma mansoni to praziquantel treatment among responding and persistent hotspot villages along the Kenyan shore of Lake Victoria. Am. J. Tropical Med. Hyg. 101, 6577 (2019).

CAS Article Google Scholar

Assar, R. K. et al. Characteristics of persistent hotspots of Schistosoma mansoni in western Cte dIvoire. Parasit. Vectors 13, 337 (2020).

PubMed PubMed Central Article CAS Google Scholar

Kittur, N. et al. Persistent hotspots in schistosomiasis consortium for operational research and evaluation studies for gaining and sustaining control of schistosomiasis after four years of mass drug administration of praziquantel. Am. J. Trop. Med. Hyg. 101, 617627 (2019).

PubMed PubMed Central Article Google Scholar

Wiegand, R. E. et al. A persistent hotspot of Schistosoma mansoni infection in a five-year randomized trial of praziquantel preventative chemotherapy strategies. J. Infect. Dis. 216, 14251433 (2017).

PubMed PubMed Central Article Google Scholar

Hedtke, S. M. et al. Genomic epidemiology in filarial nematodes: transforming the basis for elimination program decisions. Front. Genet. 10, 1282 (2019).

CAS PubMed Article PubMed Central Google Scholar

Doyle, S. R. & Cotton, J. A. Genome-wide approaches to investigate anthelmintic resistance. Trends Parasitol. 35, 289301 (2019).

CAS PubMed Article PubMed Central Google Scholar

Crellen, T. et al. Whole genome resequencing of the human parasite Schistosoma mansoni reveals population history and effects of selection. Sci. Rep. 6, 113 (2016).

Article CAS Google Scholar

Gower, C. M. et al. Population genetic structure of Schistosoma mansoni and Schistosoma haematobium from across six sub-Saharan African countries: implications for epidemiology, evolution and control. Acta Trop. 128, 261274 (2013).

PubMed Article PubMed Central Google Scholar

Standley, C., Kabatereine, N., Lange, C., Lwambo, N. & Stothard, J. Molecular epidemiology and phylogeography of Schistosoma mansoni around Lake Victoria. Parasitology 137, 19371949 (2010).

CAS PubMed Article PubMed Central Google Scholar

Faust, C. L. et al. Two-year longitudinal survey reveals high genetic diversity of Schistosoma mansoni with adult worms surviving praziquantel treatment at the start of mass drug administration in Uganda. Parasit. Vectors 12, 607 (2019).

PubMed PubMed Central Article Google Scholar

Stothard, J. R. et al. Molecular epidemiology of Schistosoma mansoni in Uganda: DNA barcoding reveals substantial genetic diversity within Lake Albert and Lake Victoria populations. Parasitology 136, 18131824 (2009).

CAS PubMed Article PubMed Central Google Scholar

Norton, A. J. et al. Genetic consequences of mass human chemotherapy for Schistosoma mansoni: population structure pre- and post-praziquantel treatment in Tanzania. Am. J. Trop. Med. Hyg. 83, 951957 (2010).

PubMed PubMed Central Article Google Scholar

Blanton, R. E. et al. Schistosoma mansoni population structure and persistence after praziquantel treatment in two villages of Bahia, Brazil. Int. J. Parasitol. 41, 10931099 (2011).

PubMed PubMed Central Article Google Scholar

Gower, C. M. et al. Phenotypic and genotypic monitoring of Schistosoma mansoni in Tanzanian schoolchildren five years into a preventative chemotherapy national control programme. Parasit. Vectors 10, 593 (2017).

PubMed PubMed Central Article CAS Google Scholar

Chevalier, F. D. et al. Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment. PLoS Pathog. 15, e1007881 (2019).

CAS PubMed PubMed Central Article Google Scholar

Platt, R. N. et al. Ancient hybridization and adaptive introgression of an invadolysin gene in schistosome parasites. Mol. Biol. Evol. 36, 21272142 (2019).

PubMed PubMed Central Article CAS Google Scholar

Shortt, J. A. et al. Population genomic analyses of schistosome parasites highlight critical challenges facing endgame elimination efforts. Sci. Rep. 11, 6884 (2021).

ADS CAS PubMed PubMed Central Article Google Scholar

Truscott, J. E. et al. A comparison of two mathematical models of the impact of mass drug administration on the transmission and control of schistosomiasis. Epidemics 18, 2937 (2017).

CAS PubMed PubMed Central Article Google Scholar

Bouzat, J. L. Conservation genetics of population bottlenecks: the role of chance, selection, and history. Conserv. Genet. 11, 463478 (2010).

Article Google Scholar

Andrews, P. Praziquantel: mechanisms of anti-schistosomal activity. Pharmacol. Ther. 29, 129156 (1985).

CAS PubMed Article PubMed Central Google Scholar

Cioli, D. & Pica-Mattoccia, L. Praziquantel. Parasitol. Res. 90, S3S9 (2003).

Caffrey, C. R. Schistosomiasis and its treatment. Future Med. Chem. 7, 675676 (2015).

CAS PubMed Article PubMed Central Google Scholar

Kaplan, R. M. & Vidyashankar, A. N. An inconvenient truth: global worming and anthelmintic resistance. Vet. Parasitol. 186, 7078 (2012).

PubMed Article PubMed Central Google Scholar

Rose, H. et al. Widespread anthelmintic resistance in European farmed ruminants: a systematic review. Vet. Rec. 176, 546 (2015).

CAS PubMed Article PubMed Central Google Scholar

Schwab, A. E., Boakye, D. A., Kyelem, D. & Prichard, R. K. Detection of benzimidazole resistance-associated mutations in the filarial nematode Wuchereria bancrofti and evidence for selection by albendazole and ivermectin combination treatment. Am. J. Trop. Med. Hyg. 73, 234238 (2005).

CAS PubMed Article PubMed Central Google Scholar

Fallon, P. G. & Doenhoff, M. J. Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific. Am. J. Trop. Med. Hyg. 51, 8388 (1994).

CAS PubMed Article Google Scholar

Couto, F. F. B. et al. Schistosoma mansoni: a method for inducing resistance to praziquantel using infected Biomphalaria glabrata snails. Mem. Inst. Oswaldo Cruz 106, 153157 (2011).

CAS PubMed Article PubMed Central Google Scholar

Mwangi, I. N. et al. Praziquantel sensitivity of Kenyan Schistosoma mansoni isolates and the generation of a laboratory strain with reduced susceptibility to the drug. Int. J. Parasitol. Drugs Drug Resist. 4, 296300 (2014).

PubMed PubMed Central Article Google Scholar

Lamberton, P. H. L., Faust, C. L. & Webster, J. P. Praziquantel decreases fecundity in Schistosoma mansoni adult worms that survive treatment: evidence from a laboratory life-history trade-offs selection study. Infect. Dis. Poverty 6, 110 (2017).

PubMed PubMed Central Article Google Scholar

Stelma, F. F. et al. Efficacy and side effects of praziquantel in an epidemic focus of Schistosoma mansoni. Am. J. Trop. Med. Hyg. 53, 167170 (1995).

CAS PubMed Article Google Scholar

Melman, S. D. et al. Reduced susceptibility to praziquantel among naturally occurring Kenyan isolates of Schistosoma mansoni. PLoS Negl. Trop. Dis. 3, e504 (2009).

PubMed PubMed Central Article CAS Google Scholar

Crellen, T. et al. Reduced efficacy of praziquantel against Schistosoma mansoni is associated with multiple rounds of mass drug administration. Clin. Infect. Dis. 63, 11511159 (2016).

CAS PubMed PubMed Central Google Scholar

King, C. H., Muchiri, E. M. & Ouma, J. H. Evidence against rapid emergence of praziquantel resistance in Schistosoma haematobium, Kenya. Emerg. Infect. Dis. 6, 585594 (2000).

CAS PubMed PubMed Central Article Google Scholar

Gryseels, B. et al. Are poor responses to praziquantel for the treatment of Schistosoma mansoni infections in Senegal due to resistance? An overview of the evidence. Trop. Med. Int. Health 6, 864873 (2001).

CAS PubMed Article Google Scholar

Fenwick, A. & Webster, J. P. Schistosomiasis: challenges for control, treatment and drug resistance. Curr. Opin. Infect. Dis. 19, 577582 (2006).

PubMed Article Google Scholar

Albonico, M. et al. Monitoring the efficacy of drugs for neglected tropical diseases controlled by preventive chemotherapy. J. Glob. Antimicrob. Resist 3, 229236 (2015).

CAS PubMed PubMed Central Article Google Scholar

Fukushige, M., Chase-Topping, M., Woolhouse, M. E. J. & Mutapi, F. Efficacy of praziquantel has been maintained over four decades (from 1977 to 2018): a systematic review and meta-analysis of factors influence its efficacy. PLoS Negl. Trop. Dis. 15, e0009189 (2021).

CAS PubMed PubMed Central Article Google Scholar

Hodgkinson, J. E. et al. Refugia and anthelmintic resistance: concepts and challenges. Int. J. Parasitol. Drugs Drug Resist. 10, 5157 (2019).

PubMed PubMed Central Article Google Scholar

Walker, M. et al. New approaches to measuring anthelminthic drug efficacy: parasitological responses of childhood schistosome infections to treatment with praziquantel. Parasit. Vectors 9, 41 (2016).

PubMed PubMed Central Article CAS Google Scholar

Kittur, N. et al. Defining persistent hotspots: areas that fail to decrease meaningfully in prevalence after multiple years of mass drug administration with praziquantel for control of schistosomiasis. Am. J. Trop. Med. Hyg. 97, 18101817 (2017).

PubMed PubMed Central Article Google Scholar

Levecke, B. et al. Evaluation of the therapeutic efficacy of praziquantel against schistosomes in seven countries with ongoing large-scale deworming programs. Int. J. Parasitol. Drugs Drug Resist. 14, 183187 (2020).

CAS PubMed PubMed Central Article Google Scholar

Nei, M., Maruyama, T. & Chakraborty, R. The bottleneck effect and genetic variability in populations. Evolution 29, 110 (1975).

PubMed Article PubMed Central Google Scholar

Gattepaille, L. M., Jakobsson, M. & Blum, M. G. B. Inferring population size changes with sequence and SNP data: lessons from human bottlenecks. Heredity 110, 409419 (2013).

CAS PubMed PubMed Central Article Google Scholar

Kohn, A. B., Anderson, P. A. V., Roberts-Misterly, J. M. & Greenberg, R. M. Schistosome Calcium Channel Subunits: unusual modulatory effects and potential role in the action of the antischistosomal drug praziquantel. J. Biol. Chem. 276, 3687336876 (2001).

Read more here:
Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration - Nature.com

Posted in Genome | Comments Off on Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration – Nature.com