Daily Archives: July 16, 2021

PALM BEACH, Fla., July 13, 2021 /PRNewswire/ -- CBD is the second most common active component inmarijuana. CBD is extracted directly from the hemp plant, which is a relative of the marijuana plant and is an important component of medicinal marijuana. Despite the fact that CBD is a component of marijuana, it has no hallucinogenic effects on the human mind. "In people, CBD displays no effects suggestive of any misuse or dependency potential," according to a World Health Organization report. To date, there has been no evidence of public health issues linked to the use of pure CBD and its derivatives. Water is injected with CBD particles to create CBD-infused beverages. The end product is a canned, usually sparkling beverage that tastes like flavored sparkling water or spiked seltzer.CBD beverages are becoming more popular as cannabis-infused goods, such as medicinal and recreational marijuana, become legalized across the United States and around the world. CBD's appeal has been fueled by its expanding availability combined with a growing health trend, with more and more people opting for "better-for-you" alternatives to sugary drinks. CBD-infused drinks of various types provide a great alternative, with health advantages to boot, because CBD beverages are sourced from a natural source.Active companies in the markets this week include: Grove, Inc. (NASDAQ: GRVI), Pressure BioSciences, Inc. (OTCQB: PBIO), Tilray, Inc.(NASDAQ: TLRY) (TSX: TLRY), NewAge, Inc. (NASDAQ: NBEV),Canopy Growth Corporation(NASDAQ: CGC) (TSX: WEED).

A reportfrom Facts & Factors projected that the global CBD Infused Beverages market, which was valued at around USD 3,400 million in 2020, is expected to make over USD 14,600 million by the end of 2026, with a CAGR of approximately 27.5%between 2021 and 2026.The report said: "The market for CBD-infused drinks is largely driven by the rising authorization and certification for recreational cannabis in countries, such as the United States and Canada. Furthermore, because of the increasing incidence of numerous respiratory disorders, there is a growing movement away from smoking cannabis and adopting healthier edible options, which is pushing the market growth. Furthermore, the common accessibility of CBD-infused drinks such as coffee, fruit punch, cannabis cola tea, and other CBD-infused beverages across various legal marijuanaoutlets further augments the global industry. Several key players manufacturing CBD-infused beverages also prefer investing in developing newly flavored beverages the rising usage of CBD-infused drinks in cancer patients to treat nausea, weight loss, and poor appetite is fueling market expansion. Furthermore, its growing popularity as a functional drink among athletes and sportspeople has resulted in increased product demand in the sports nutrition industry. Numerous advancements in cannabis microdosing have resulted in the creation of alcohol-free beer produced from CBD, which is likely to fuel market expansion"

Pressure BioSciences, Inc. (OTCQB: PBIO) BREAKING NEWS: Pressure BioSciences UST-Enabled Nanoemulsions Soar Past One Year Stability Goal; Results Open Explosive Growth Potential for Water-Soluble CBD-Infused Beverages Worldwide - Pressure BioSciences, a leader in the development and sale of broadly enabling, pressure-based instruments, consumables, and innovative services to the worldwide biotechnology, biotherapeutics, cosmetics, nutraceuticals, agrochemical, and food & beverage industries, today announced that processing hemp-derived cannabidiol ("CBD") with its Ultra Shear Technology ("UST") platform produces high quality water-soluble nanoemulsions of CBD oil in water with the critically important benefit of scientifically proven long-term stability. Specifically, the Company reported breakthrough results in which its UST processing platform produced the consistent and extremely fine nano-dispersions of CBD oil in water that are required to achieve product stability in excess of twelve months, under both cold and room temperature storage conditions, even with multiple freeze-thaw cycles, without any visible or measurable deterioration of the nanoemulsified product.

CBD is a non-psychoactive, oil-soluble compound extracted from the cannabis plant, and is typically marketed in a plant oil solution. CBD has been widely reported to offer numerous health benefits from stress and anxiety relief, to Schizophrenia, decreased seizures, muscle, joint, cancer and other pain, and reduced inflammation. Because CBD is oil-based, its ingestion or topical application typically results in poor absorption in water-based living systems, like humans. For example, the World Health Organization estimated CBD bioavailability from oral delivery of oil-based formulations was just 6%. That means most ingested CBD is wasted, passing through the body without being absorbed. Consequently, there is enormous interest in the development of truly water-soluble CBD, to achieve efficient dosing delivery, absorption, and bioavailability from foods and beverages.

ProVerde Laboratories is one of the most advanced analytical testing service laboratories in the country offering testing of cannabis-derived materials, including cannabinoid profiling and particle size characterization.Dr. Christopher Hudalla, President and Chief Scientific Officer of ProVerde Labs provided powerful perspective: "We test hundreds of cannabis products on a regular basis, and the overwhelming diversity of so-called water-soluble products that we test consistently suffer from poor particle uniformity and a lack of long-term stability. This often results in cannabinoid degradation, phase separation, coalescence and or sediment formation. The introduction of a new technology platform that can consistently produce the necessary ultra-low droplet size nanoemulsions required to deliver reliable shelf life of over one year, including resistance to freeze-thaw challenges, will be a pivotal inflection point and an explosive growth opportunity in the CBD and cannabis-derived products industry."

Mr. John Westlake, Founder and President of Canopy CBD Farms, LLC., further confirmed: "Scientific data strongly supports the critical need for hemp-derived CBD oil to be processed into water-soluble nanoemulsions to achieve the highest levels of absorption and bioavailability with optimal dosing safety and overall product cost efficiency for manufacturers and consumers. For commercial success, these CBD nanoemulsions must also be long-term stable, to help ensure that the CBD-containing product has the best opportunity to achieve its promise after months in distribution and shelf storage.In my many years in the cannabis market, this is the first time I have observed such an accomplishment: a high quality nanoemulsion of CBD oil in water with over one year of real time, rock-solid, cold and room temperature stability, even following multiple freeze-thaw cycles. These results are highly impressive."

Mr. Gary B. Smejkal, Senior Research Scientist at PBI, explained the Company's breakthrough: "Achieving long-term stability of nanoemulsions requires production processes that attain consistent, extremely low oil droplet sizes in water.Our unique formulations and patented UST processing platform use unprecedentedly high pressures to achieve repeated cycles of extreme shearing forces at controlled temperatures and flow rates, which we believe deliver the highest quality and most long-term stable CBD nanoemulsions available in the world today."

Mr. John B. Hollister, Director of Sales and Marketing at PBI, expanded on the opportunity: "CBD-containing nanoemulsions created by our innovative and proprietary UST processing platform have the potential to revolutionize the rapidly growing cannabis market, not just in food and beverage, but in multiple other areas as well, including biotherapeutics, nutraceuticals, agrochem, and cosmetics. From truly clear, water-soluble infusions in beverages that are cold and room temperature long-term stable, to predictable dosing with much faster onset of action than other edible forms, we believe the benefits and appeal for consumers will be tremendous. We are excited to have achieved this historic milestone of surpassing one-year of real time cold and room temperature stability and look forward to the impending commercial release of our initial UST-based nanoemulsion system by or before the end of 2021." CONTINUED Read this full release and more news for Pressure BioSciences at: https://www.financialnewsmedia.com/news-pbio/

Other recent developments in the markets include:

Tilray, Inc.(NASDAQ: TLRY) (TSX: TLRY), a leading global cannabis-lifestyle and consumer packaged goods company, recently announced that its SweetWater Brewing Company has launched a new product collaboration with Canada's leading craft cannabis brand Broken Coast Cannabis Ltd., a brand under the Tilray portfolio based in British Columbia and geared toward the premium cannabis market. "Broken Coast BC Lager" is the first cross-brand product developed in partnership with leading craft brands, SweetWater and Broken Coast, and Tilray's first Canadian cannabis brand introduction into the U.S.

"We're here to build great brands that deliver products consumers enjoy, and we look forward to having some fun along the way," said Irwin D. Simon, Tilray's Chairman, and Chief Executive Officer. "This cross-collaboration between SweetWater and Broken Coast is the first among many milestones in our growth and execution strategy to introduce our great Canadian cannabis brands in the U.S. and connect our consumers to other brands in our portfolio."

NewAge, Inc. (NASDAQ: NBEV),the Colorado-based organic and healthy products company intending to become the world's leading social selling and distribution company, recently announced that it has formed a manufacturing partnership with and agreed to sell its US manufacturing operations to Taiwan-based TCI Co., Ltd.

Taiwan stock exchange listed TCI was founded in 1980, and has grown to almost $300 million in annual revenue with more than 1,150 employees worldwide. TCI is one of the preeminent manufacturers of functional drinks, skincare, nutritional supplements and other healthy products with manufacturing and biotech operations in Taiwan, PRC, Japan, Netherlands and now the US, with exports to more than 50 countries worldwide. TCI is also a leader in research and development with an extensive bio-diversified portfolio with over 200 patents, and was recently recognized by the Financial Times as one of Asia's fastest-growing companies.

Canopy Growth Corporation(NASDAQ: CGC) (TSX: WEED) and The Supreme Cannabis Company, Inc. (OTCQX: SPRWF) recently announced the completion of the previously announced arrangement (the "Arrangement") whereby Canopy has acquired all of the issued and outstanding common shares of Supreme (the "Supreme Shares").

As Canopy continues to focus on the premium flower segment, the addition of 7ACRES and the 7ACRES Craft Collective enhances Canopy's leading market share position and supplements its production capacity through the acquisition of Supreme's low-cost, scalable cultivation facility inKincardine, Ontario. This facility has a proven capability for producing high-quality flower from sought-after strains that have earned Supreme's brands their loyal consumer followings. Additionally, the acquisition of Supreme further strengthens Canopy's overall leadership position within the Canadian recreational market and creates a pro forma Q4 FY 2021 market share of 18.1%. Furthermore, the acquisition creates the opportunity for immediate value creation with an estimated$30 millionin synergies to be captured within the next two years.

Grove, Inc. (NASDAQ: GRVI) recently expanded into the rapidly growing plant-based market for gummy vitamins with their newest product line, Qubes. The brand currently offers customers unique products from Apple Cider Vinegar + Acai, Turmeric Immunity, and an upcoming Algae Oil supplement that will act as a plant-based alternative to fish oil for daily Omega-3 intake.

Qubes gummies are completely free of preservatives, chemicals, corn syrup, allergens, soy, dairy, wheat, salicylates, artificial ingredients, artificial sweeteners, flavors or colors. This newest launch is set to take advantage of the growing demand in the vitamin space. "The global gummy vitamins market size is estimated to be valued at USD 5.9 billion in 2020 and projected to reach USD 10.6 billion by 2025, recording a CAGR of 12.5%"

DISCLAIMER: FN Media Group LLC (FNM), which owns and operates FinancialNewsMedia.com and MarketNewsUpdates.com, is a third party publisher and news dissemination service provider, which disseminates electronic information through multiple online media channels.FNM is NOT affiliated in any manner with any company mentioned herein.FNM and its affiliated companies are a news dissemination solutions provider and are NOT a registered broker/dealer/analyst/adviser, holds no investment licenses and may NOT sell, offer to sell or offer to buy any security. FNM's market updates, news alerts and corporate profiles are NOT a solicitation or recommendation to buy, sell or hold securities.The material in this release is intended to be strictly informational and is NEVER to be construed or interpreted as research material. All readers are strongly urged to perform research and due diligence on their own and consult a licensed financial professional before considering any level of investing in stocks. All material included herein is republished content and details which were previously disseminated by the companies mentioned in this release. FNM is not liable for any investment decisions by its readers or subscribers. Investors are cautioned that they may lose all or a portion of their investment when investing in stocks.For current services performed FNM has been compensated forty six hundred dollars for news coverage of the current press releases issued by Pressure BioSciences, Inc. by the Company. FNM HOLDS NO SHARES OF ANY COMPANY NAMED IN THIS RELEASE.

This release contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E the Securities Exchange Act of 1934, as amended and such forward-looking statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. "Forward-looking statements" describe future expectations, plans, results, or strategies and are generally preceded by words such as "may", "future", "plan" or "planned", "will" or "should", "expected," "anticipates", "draft", "eventually" or "projected". You are cautioned that such statements are subject to a multitude of risks and uncertainties that could cause future circumstances, events, or results to differ materially from those projected in the forward-looking statements, including the risks that actual results may differ materially from those projected in the forward-looking statements as a result of various factors, and other risks identified in a company's annual report on Form 10-K or 10-KSB and other filings made by such company with the Securities and Exchange Commission. You should consider these factors in evaluating the forward-looking statements included herein, and not place undue reliance on such statements. The forward-looking statements in this release are made as of the date hereof and FNM undertakes no obligation to update such statements.

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CBD-Infused Beverages Market Is Expected to Exceed $14 Billion by End of 2026 - PRNewswire

The global pet CBD market is projected to witness considerable growth over the coming years of the forecast period. This growth of the market is fueled by the growing research funding provided by some of the large corporations working in the market. Pet CBD market has also benefitted from the growing awareness among people. More and more veterinary professionals are recommending these products for treating the chronic disorders occurring among pets.

Global Pet CBD Market Notable Developments

The global pet CBD market shows a fragmented vendor landscape with the presence of large pool of key players. Some of the key players in the market include names such as Bluebird Botanicals, Kats Naturals, PotNetwork Holdings Inc., Diamond CBD, Pet Releaf, Cannabis Strategies Acquisition Corp., and Pure Spectrum among others.

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Some of the recent developments in the global pet CBD market are listed below:

Global Pet CBD Market Drivers and Restraints

One of the biggest driving factor for the growth of the global pet CBD market is the increasing prevalence of GIT and bowel related disorders among pets. Just like humans, pets too suffer from sleeping or anxiety disorders and thus need special treatment. This has thus worked in favor of the pet CBD market.

Another important driving factor for the growth of the global pet CBD market is the growing occurrence of cancer related complications. Cannabidiol treatment has thus become an important method for treating pet and helping the market to grow. Moreover, there has been a growing demand for different CBD derivatives in the market to treat chronic pet disorders. At times, there are cases of pet suffering from heart disorders or tachycardia. Treatment of such chronic disorders is also creating great demand for the market.

Global Pet CBD Market Geographical Outlook

In terms of geographical segmentation, the global pet CBD market has five key regional segments namely, Europe, Latin America, North America, Asia Pacific, and the Middle East and Africa. Of these regional segments, currently North America is the most dominating one followed by Europe. The growth of the North America region is due to the presence of several animal research and development facilities. Whereas, the growth of the Europe market is due to the high prevalence of GIT related and bowel related disorders among the pets. In coming years, these two regions are expected to continue to lead the global pet CBD market.

Asia Pacific is expected to undergo considerable transformation over the course of the given forecast period of 2018 to 2028. The growth of the market can be primarily attributed to expanding production facilities in the region. Manufacturers are investing to expand the production of CBD capsules and oil cakes for the pets in countries such as India and China. It is expected to boost the development of the market in the region.

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Global Pet CBD Market Segmentation

Source Type

Indication Type

End-user

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Pet CBD Market drive by the increasing prevalence of GIT and bowel related disorders among pets | TMR Research Study - BioSpace

Cannabis plants have been used to ease pain going back to 2900BC. Recently, researchers found that there are particular cannabinoids with pain-relieving effects. One of the prominent phytocannabinoids is considered cannabidiol (also known as CBD) that is thought to interact with receptors and neurotransmitters located all over your body and possess anti-inflammatory properties to aid in relieving pain and chronic aches.

Aside from the potential benefits of CBD, there are several approaches to take this beneficial supplement. You can take it in the form of drinks like sparkling water, edibles like chewing sweets, as a spray and topical, among others. Here are some common ways of using CBD oil for pain relief.

CBD oils and oral tinctures are usually packaged in small, tinted bottles with a glass dropper for a convenient measure and more flexible CBD dosage. Depending on your specific needs or how you feel at the moment, you can either limit your intake to a few drops of CBD or consume more for a stronger effect.

With such a type of product, you can also choose whether you will take CBD orally or put the oil under your tongue (sublingually) to improve bioavailability. This way CBD is absorbed through the capillaries and goes directly into the bloodstream, which in turn provides beneficial effects faster.

With their optimal convenience, edibles are a great and simple method to try CBD, especially for the first time. Various edible products such as CBD gummies, capsules, chocolate and many others typically come with a pre-measured dose of CBD oil, which eliminates special preparations before the intake and helps you to easily track consumed dosage.

However, depending on individual metabolism rate, oral products are usually slowly absorbed by the body as they must pass through your digestive tract before hitting your bloodstream and offering the first positive effects.

When it comes to targeted pain relief different topicals are considered the best option. Topical CBD products like lotions, balms, roll-on sticks, ointments as well as transdermal patches work in a number of different ways to decrease pain, reduce inflammation and increase the number of endocannabinoids within the body as receptors of the endocannabinoid system are also found in the skin.

Therefore, CBD-infused topicals are used directly in problem areas. For example, for joint pain, swelling or open wound as well as different skin issues like dryness or itching. Applying CBD can provide soothing, anti-inflammatory, antioxidant, antibacterial and anti-fungal effects.

Whether it is a CBD vape pen, vape pod or cartridge, inhaling CBD oil through a vaping device is considered one of the fastest ways to deliver CBD into your system.

Since CBD is supplied directly to the lungs, it is absorbed into the body more quickly, which allows users to experience the potential benefits of cannabidiol almost instantly. While CBD vaping ensures quick and effective absorption, it is essential to remember that prolonged vaping might have negative effects on your lungs.

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Spotlight: CBD For Pain & Aches: Four Best Ways To Use CBD To Find Relief - Magnetic Magazine

Latest released the research study on CBD Oil Extract Market, offers a detailed overview of the factors influencing the global business scope. CBD Oil Extract Market research report shows the latest market insights with upcoming trends and breakdown of the products and services. The report provides key statistics on the market status, size, share, growth factors of the CBD Oil Extract. The report basic offers a basic understanding of the global CBD Oil Extract industry competitors, the sales channel, growth potential, potentially disruptive trends, industry product innovations, and the value/volume of size, market segments, and market share of the best actors/products. Regionally, this report categorizes the production, apparent consumption, export and import of CBD Oil Extract in North America, Europe, China, Japan, Southeast Asia and India.

CBD Oil Extract Marketsize is valued at USD 25.57 billion by 2027 and is expected grow at a compound annual growth rate of 21.0% in the forecast period of 2020 to 2027 due to the increasing preferences ofoiland tinctures extracted from cannabis which is primarily driving the market growth rate.

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Beside this, the increasing number of research activities for the rising number of benefits as well as government approvals will produce lucrative opportunities for the growth of the CBD oil extract market.

The report profiles the key players in the industry, along with a detailed analysis of their individual positions against the regional landscape. The study conducts SWOT analysis to evaluate strengths and weaknesses of the key players in the CBD Oil Extract market. The researcher provides an extensive analysis of the CBD Oil Extract market size, share, trends, overall earnings, gross revenue, and profit margin to accurately draw a forecast and provide expert insights to investors to keep them updated with the trends in the market.

CBD Oil Extract Market Scenario

According to Data Bridge Market Research the market for CBD oil extract is accelerating because of the legalization of cannabis-based CBD products. Also the, high adoption of CBD-based products in various medical treatments as well as growing retail sector are also expected to fuel the demand of the CBD oil extract market over the forecast period of 2020 to 2027. Whereas, the high cost of products along with various legalization issues in various economies will obstruct the growth of the CBD oil extract market in the above mentioned forecast period.

The Segments and Sub-Section of CBD Oil Extract Market are shown below:

By Source Type (Hemp, Marijuana)

By Distribution Channel (B2B, B2C)

By End Use (Medical, Personal use, Pharmaceutical, Wellness)

The Top Driving Players Operating in the Market Covered in this report:

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The overall market size has been derived using both primary and secondary source. The research process begins with an exhaustive secondary research using internal and external sources to obtain qualitative and quantitative information related to the market. It also provides the overview and forecast for the global CBD Oil Extract market based on all the segmentation provided with respect to five major reasons such as North America, Europe, Asia-Pacific, Middle East and Africa, and South America. Also, primary interview were conducted with industry participants and commentators in order to validate data and analysis. The participants who typically take part in such a process include industry expert such as VPs, business development managers, market intelligence managers and national sales managers, and external consultant such as valuation experts, research analysts and key opinion leaders specializing in the CBD Oil Extract industry.

Global CBD Oil Extract Market Scope and Market Size

CBD oil extract market is segmented on the basis of source type, distribution channeland end use. The growth amongst these segments will help you analyse meagre growth segments in the industries, and provide the users with valuable market overview and market insights to help them in making strategic decisions for identification of core market applications.

Based onsource type, the CBD oil extract market is segmented into hemp, and marijuana

On the basis of distribution channel, the CBD oil extract market is segmented into B2B, and B2C. B2C has been further segmented into hospital pharmacies, online and retail stores.

CBD oil extract market has also been segmented based onthe end use into medical, personal use, pharmaceutical, and wellness. Medical has been further segmented into chronic pain, mental disorders, cancer and others. Wellness has been further segmented into food & beverages, personal care &cosmetics, nutraceuticals, and others.

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Data Bridge Market ResearchPvtLtdis a multinational management consulting firm with offices in India and Canada. As an innovative and neoteric market analysis and advisory company with unmatched durability level and advanced approaches. We are committed to uncover the best consumer prospects and to foster useful knowledge for your company to succeed in the market.

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CBD Oil Extract Market Share, Size 2021 Emerging Rapidly with Global Latest Trends, Growth, Revenue, Demand and Forecast to 2027 The JC Star - The JC...

This U.S. Hemp Oil Marketreport also endows with an exhaustive survey of key players in the market which is based on a range of objectives of an organization such as profiling, the product outline, the quantity of production, required raw material, and the financial health of the organization. It also explains what the market definition, classifications, applications, engagements, and global industry trends are. The report puts light on the entire market trends and analyses the effect of buyers, consumers, substitutes, new entrants, competitors, and suppliers on the market.

U.S. hemp oil market is expected to gain market growth in the forecast period of 2020 to 2027. Data Bridge Market Research analyses that the market is growing at a CAGR of 26.8% in the forecast period of 2020 to 2027 and expected to reach USD 4,906.54 thousand by 2027. Hemp oil market is dominating as people are becoming more health conscious and they prefer organic product which is good for health.

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U.S. Hemp Oil Market Scenario:

Hemp and marijuana come from the same family of plants, but their function, cultivation and application are entirely different. In fact, weed has a strong THC rating and is used for medical or leisure purposes. Hemp has negligible levels of THC (but CBD is high) and is used in dietary supplements, skin care, clothes, and paper among others. As with oranges and citrus fruits, both hemp and marijuana have a distinctive appearance and a distinct chemical composition. Owing to shifts in C sativa plant regulations as well as increasing sale of new goods the variations between hemp and CBD oils were still uncertain.

Key Insights incorporated in the U.S. Hemp Oil market report

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Conducts Overall U.S. HEMP OIL Market Segmentation:

By Products (Hemp Seed Oil, CBD Oil, Hemp Flower Oil),

Type (Original, and Blended),

Source (Organic and Inorganic),

Component (Hemp Seed Oil, Hemp CBD Oil),

Distribution Channel (Direct and Indirect),

Application (Food and Beverages, Personal Care/Cosmetics, Pharma and Nutraceuticals, Industrial Application, Agriculture, Animal Feed, Others)

Customized specific regional and country-level reports for the following areas.

The country section of the report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points such as new sales, replacement sales, country demographics, regulatory acts and import-export tariffs are some of the major pointers used to forecast the market scenario for individual countries. Also, presence and availability of North America brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of sales channels are considered while providing forecast analysis of the country data.

Thinking One Step Ahead

In todays competitive world you need to think one step ahead to pursue your competitors, our research offers reviews about key players, major collaborations, union & acquisitions along with trending innovation and business policies to present a better understanding to drive the business in the correct direction.

In conclusion, the U.S. Hemp Oil Market report is a genuine source for accessing the research data which is projected to exponentially grow your business. The report provides information such as economic scenarios, benefits, limits, trends, market growth rates, and figures. SWOT analysis and Porters Five analysis is also incorporated in the report.We even do customized Reports for our customers; we can add the list of Manufactures or application type or product type that you need in the report. Ask for it @https://www.databridgemarketresearch.com/speak-to-analyst/?dbmr=us-hemp-oil-market&SB

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Some Points from Table of Content

Chapter 1 U.S. Hemp Oil Introduction and Market Overview

1.1 Objectives of the Study

1.2 Overview of U.S. Hemp Oil

1.3 Scope of The Study

1.3.1 Key Market Segments

1.3.2 Players Covered

1.3.3 COVID-19s impact on the U.S. Hemp Oil industry

1.4 Methodology of The Study

1.5 Research Data Source

Chapter 2 Executive Summary

Chapter 3 Industry Chain Analysis

Chapter 4 Global U.S. Hemp Oil Market, by Type

Chapter 5 U.S. Hemp Oil Market, by Application

Chapter 6 Global U.S. Hemp Oil Market Analysis by Regions

Chapter 7 North America U.S. Hemp Oil Market Analysis by Countries

Chapter 8 Europe U.S. Hemp Oil Market Analysis by Countries

Chapter 9 Asia Pacific U.S. Hemp Oil Market Analysis by Countries

Chapter 10 Middle East and Africa U.S. Hemp Oil Market Analysis by Countries

Chapter 11 South America U.S. Hemp Oil Market Analysis by Countries

Chapter 12 Competitive Landscape

Chapter 13 Industry Outlook

Chapter 14 Global U.S. Hemp Oil Market Forecast

Chapter 15 New Project Feasibility Analysis

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US Hemp Oil Market 2021 Recent Industry Developments and Growth Strategies Adopted by Top Key Players Worldwide and Assessment to 2027 26 Sports -...

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BestCBDpromo Offers the Best Daily Deals On CBD Oils, Edibles, Drinks, Topicals and More - Digital Journal

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Key competitors of the global CBD Hemp Oil market are:

Cannavest, Pharmahemp, ENDOCA, BAFA Gmbh, Protect Pharma Rakitovica, Biobloom Hemp, Deep Nature Project, Harmony, DragonflyCBD, MH medical hemp GmbH, Celtic Wind, Elixinol, HemPoland, Opencrop GmbH,

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Food Grade, Pharmaceutical Grade,

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CBD Nutraceutical, CBD Food, CBD Cosmetics, CBD Medical, Others,

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North America (United States, Canada and Mexico), Europe (Germany, France, United Kingdom, Russia, Italy, and Rest of Europe), Asia-Pacific (China, Japan, Korea, India, Southeast Asia, and Australia), South America (Brazil, Argentina, Colombia, and Rest of South America), Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa, and Rest of Middle East & Africa)

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Global CBD Hemp Oil Market 2021 Industry Future Growth, Key Player Analysis and Forecast 2026 The JC Star - The JC Star

A recently published study in the journal Scientific Reports is presenting evidence to suggest molecules called terpenes synergistically interact with cannabinoids to contribute to the therapeutic effects of cannabis. The research supports a controversial hypothesis dubbed the entourage effect, which claims the medical benefits of cannabis are not due to single cannabinoids such as THC or CBD but rather the broader interactions between various compounds in the plant.

The idea behind the entourage effect first arose in the late 1990s after a team of researchers discovered several fatty acids can enhance the activity of endogenous cannabinoids. On their own these compounds do not affect cannabinoid receptors, but when combined with naturally occurring cannabinoids they can amplify receptor activation.

Very seldom is the biological activity of the active constituent assayed together with the inactive entourage compounds, the 1998 research stated. In view of the results described above investigations of the effect of the active component in the presence of its entourage compounds may lead to observations of effects closer to those in Nature than investigations with the active component only.

This small hypothetical aside slowly grew into the belief that isolating specific chemicals from cannabis for therapeutic uses may not be as effective as administering those same chemicals in their original plant form. The idea of the entourage effect has been especially prominent in the world of cannabis, with advocates of the hypothesis arguing whole-plant extracts are more effective than isolating specific cannabinoids such as THC or CBD.

The scientific evidence proving the entourage effect, however, is still lacking. A critical review of research on the subject published last year called most work on the entourage effect unjustifiably optimistic," and warned the hypothesis is often used to justify unfounded marketing claims.

Claims of a cannabis entourage effect invoke ill-defined and unsubstantiated pharmacological activities which are commonly leveraged toward the popularization and sale of ostensible therapeutic products, the review stated. Overestimation of such claims in the scientific and lay literature has fostered their misrepresentation and abuse by a poorly regulated industry.

There are hundreds of distinct chemical compounds in cannabis. The two well-known compounds are cannabinoids tetrahydrocannabinol (THC) and cannabidiol (CBD). These are the two most active molecules in cannabis, with THC accounting for the plants popular psychoactive effects and CBD offering increasingly compelling medical uses.

Another class of compounds in cannabis are terpenes. More than 100 different terpenes have been catalogued in cannabis and the molecules often are responsible for the distinctive smell of the plant.

Advocates of the entourage effect hypothesis often point to terpenes as potentially playing a major role in the phenomenon. However a robust study published last year struggled to find any interaction between terpenes in cannabis and cannabinoid receptors. The research also did not detect any synergistic effect of terpenes when combined with THC or CBD.

This new study from researchers at the University of Arizona Health Sciences (UA) offers somewhat differing findings. Using both in vitro cell experiments and in vivo mouse models the researchers investigated the effects of four particular terpenes: alpha-humulene, geraniol, linalool and beta-pinene.

All four terpenes were found to activate CB1R receptors in lab tests. These are the most abundant cannabinoid receptors in the human body.

But why did this study see terpenes activate CB1R receptors when a prior study reached different conclusions? The UA team indicate key differences in their methodology can explain the discordant results.

[The prior] study used mixtures of terpenes, with no single terpene exceeding 50% of the mixture; they also used a maximum concentration of 10 M, while we observed receptor activation at higher concentrations, the researchers note in their new study. These differences explain our observed results, and in addition, we used an in vivo model, which will capture a broader range of potential activity than an in vitro model with very specific outputs.

The in vivo model in the new study found all four terpenes reduced pain sensation behaviors in the animals. Testing the entourage effect further the researchers used a synthetic cannabinoid called WIN55,212-2 to stimulate cannabinoid receptors.

Pain responses in the animals were reduced more significantly when terpenes were combined with WIN55,212-2, compared to administering either terpenes or WIN55,212-2 alone. The researchers hypothesize this to be an indication of some kind of entourage effect at play.

It was unexpected, in a way, says John Streicher, lead researcher on the project. It was our initial hypothesis, but we didnt necessarily expect terpenes, these simple compounds that are found in multiple plants, to produce cannabinoid-like effects.

The researchers are clear in noting these findings must still be confirmed with more relevant cannabinoids such as THC, as opposed to the synthetic cannabinoid used in the study. It is also suggested that further work will need to explore the way this potential synergistic mechanism works as it is still unclear exactly how these terpenes influence CB1R activity. And, on top of all of this, it is still unclear whether the findings of this study point to any meaningful outcome in humans.

The new study is far from definitive evidence proving the entourage effect. The majority of research still struggles to find an entourage effect in cannabis therapeutics. A recent study, for example, found no difference in effect on cancer cells when comparing pure CBD oil to hemp oils with high CBD concentrations.

Streicher isnt necessarily an entourage effect evangelist, although he does claim the phenomena is possible and he is looking closely at whether cannabis terpenes can enhance the pain-relieving effects of other drugs. The goal of his work is to find ways to reduce the side effects of common analgesia by lowering the overall dose of drugs.

A lot of people are taking Cannabis and cannabinoids for pain, says Streicher. We're interested in the concept of the entourage effect, with the idea being that maybe we can boost the modest pain-relieving efficacy of THC and not boost the psychoactive side effects, so you could have a better therapeutic.

The new study was published in the journal Scientific Reports.

Source: University of Arizona Health Sciences

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The entourage effect: Is cannabis more than just THC and CBD? - New Atlas