Daily Archives: June 18, 2021

Worldwide Biohacking Industry to 2026 – Competitive Analysis and the Impact of COVID-19 – PRNewswire

Posted: June 18, 2021 at 7:28 am

DUBLIN, June 14, 2021 /PRNewswire/ -- The "Global Biohacking Market (2021-2026) by Product, Application, Type, End-User, Geography, Competitive Analysis and the Impact of Covid-19 with Ansoff Analysis" report has been added to ResearchAndMarkets.com's offering.

Key factors, such as the innovative trends of neuro-nutrition & growing biohacking in the health & wellness space, are likely to contribute to the growth of the market. Penetration of the Internet of Things in healthcare, fitness, and consumer electronics such as fitness bands also boosts the market growth. Rising demand for smart devices and effective drugs to meet the daily healthcare needs amongst the population and the prevalence of chronic disorders are factors driving the market growth. The COVID-19 pandemic has led to a surge in market growth for the pharma industries engaged in biohacking.

However, strict government regulations governing the genetic engineering experiments, lack of funds required for research, and lack of expertise are likely to hinder the market growth. Cybersecurity practices are expected to pose a challenge for the biohacking market.

Market Segmentation

The Global Biohacking Market is segmented further based on Product, Application, Type, End-User, and Geography.

Recent Developments1. Fitbit Collaborates with Scripps Research and Stanford Medicine to Study the Role of Wearables to Detect, Track and Contain Infectious Diseases like COVID-19. - 4th April 20202. InteraXon announced a new product launch - Muse S, a Meditation Sleep Headband. - 9th January 2020

Company Profiles

Some of the companies covered in this report are Apple, THE ODIN, Thync Global, Fitbit, Synbiota, Moodmetric, HVMN, InteraXon Inc, etc.

Competitive Quadrant

The report includes a Competitive Quadrant, a proprietary tool to analyze and evaluate the position of companies based on their Industry Position score and Market Performance score. The tool uses various factors for categorizing the players into four categories. Some of these factors considered for analysis are financial performance over the last 3 years, growth strategies, innovation score, new product launches, investments, growth in market share, etc.

Why buy this report?

Report Highlights:

Key Topics Covered:

1 Report Description

2 Research Methodology

3 Executive Summary

4 Market Overview4.1 Introduction 4.2 Market Dynamics4.2.1 Drivers4.2.1.1 Innovative Trends of Neuro-Nutrition and Biohacking in The Wellness Space 4.2.1.2 Increase in The Use of Radiofrequency Identification (RFID) Technology in Medical Devices 4.2.1.3 Rising Demand for Smart Devices and Drugs 4.2.1.4 Penetration of Internet of Things (IoT) In Healthcare, Fitness, and Consumer Electronics 4.2.2 Restraints4.2.2.1 Stringent Government Regulations Governing the Genetic Engineering Experiments4.2.2.2 Lack of Funds Required for Research 4.2.2.3 Lack of Expertise 4.2.3 Opportunities4.2.3.1 Lab Experiments with The Use of Medical, Nutritional, and Electronic Technique 4.2.3.2 Advancement in Technologies4.2.3.3 The Sharp Rise in Chronic Diseases Coupled with The Growing Geriatric Population4.2.4 Challenges4.2.4.1 Cyber Security Concerns4.3 Trends

5 Market Analysis5.1 Porter's Five Forces Analysis5.2 Impact of COVID-195.3 Ansoff Matrix Analysis

6 Global Biohacking Market, By Product6.1 Introduction6.2 Smart Drugs6.3 Sensors6.4 Strains6.5 Others

7 Global Biohacking Market, By Application7.1 Introduction 7.2 Synthetic Biology7.3 Genetic Engineering7.4 Forensic Science7.5 Diagnosis & Treatment7.6 Drug Testing

8 Global Biohacking Market, By Type8.1 Introduction8.2 Inside8.3 Outside

9 Global Biohacking Market, By End User9.1 Introduction9.2 Pharmaceutical & Biotechnology Companies9.3 Forensic Laboratories9.4 Others

10 Global Biohacking Market, By Geography10.1 Introduction10.2 North America10.2.1 US10.2.2 Canada10.2.3 Mexico10.3 South America10.3.1 Brazil10.3.2 Argentina10.4 Europe10.4.1 UK10.4.2 France10.4.3 Germany10.4.4 Italy10.4.5 Spain10.4.6 Rest of Europe10.5 Asia-Pacific10.5.1 China10.5.2 Japan10.5.3 India10.5.4 Indonesia10.5.5 Malaysia10.5.6 South Korea10.5.7 Australia10.5.8 Russia10.5.9 Rest of APAC10.6 Rest of the World10.6.1 Qatar10.6.2 Saudi Arabia10.6.3 South Africa10.6.4 United Arab Emirates10.6.5 Latin America

11 Competitive Landscape11.1 Competitive Quadrant11.2 Market Share Analysis11.3 Competitive Scenario11.3.1 Mergers & Acquisitions11.3.2 Agreement, Collaborations, & Partnerships11.3.3 New Product Launches & Enhancements11.3.4 Investments & funding

12 Company Profiles12.1 Apple12.2 THE ODIN 12.3 Thync Global 12.4 Fitbit 12.5 Synbiota 12.6 Moodmetric 12.7 HVMN 12.8 InteraXon 12.9 Modern AlkaMe12.10 Behavioral Tech

13 Appendix

For more information about this report visit https://www.researchandmarkets.com/r/25qr1p

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Eligo Presents Preclinical Data Demonstrating for the First Time that Gut Microbiome Modulation via Delivery of CRISPR Nuclease Impacts Disease…

Posted: at 7:28 am

In-vivo data in disease model further supports development of Eligo's CRISPR-Cas antimicrobial strategies and itsEligobiotics platform

Phase 1 trial for EB003 lead candidate expected to commence in Q2'22; Orphan Drug Designation granted by the EMA

PARIS, June 15, 2021 /PRNewswire/ -- Eligo Bioscience SA, a Paris, France-based microbiome engineering company, today announced that the Company presented preclinical data on its lead drug candidate, EB003, for the treatment of severe diarrhea induced by shiga-toxin (Stx) producing E. coli (STEC, leading to Hemolytic Uremic Syndrome), at the 14thAnnual CRISPR 2021 meeting held June 1-10, 2021. The data presented further supports development of CRISPR-Cas antimicrobial strategies against STEC and other microbiome bacterial targets utilizing Eligo's proprietary Eligobiotics platform. Eligo's proprietary technology is protected by over 20 patent families, including the 2013 foundational IP on CRISPR antimicrobials.EB003 has been granted Orphan Drug Designation by the EMA.

"The data presented virtually this year at the CRISPR meeting continues to support the potential of our lead candidate EB003 and the use of the Eligobioticsplatform to modulate bacterial populations of the microbiome with unprecedented precision," said Xavier Duportet, Ph.D., Chief Executive Officer of Eligo Bioscience. "EB003 demonstrated efficacy across multiple in vitro and in vivo models. Moreover, we observed significantly reduced STEC colonization and alleviated symptoms in 100% of treated animals in a disease model representative of the intended patient population.We are very excited about these findings, how they support progression of EB003, and the clear demonstration of effective application of our proprietary platform."

Dr. Duportet continued, "This is indeed the first time that symptom alleviation has been achieved via the delivery of exogenous nuclease in a gut infection model, building on the foundational invention of this technology. Even more exciting is the fact that bacterial killing is solely achieved by the nuclease activity as opposed to the lytic cycle of the phage, therefore enabling a true modulation at the strain level based on the sole presence of a deleterious gene in bacteria.We are looking forward to advancing EB003 into the clinic next year."

The virtual presentation describes efficacy data in in vitro collections of epidemiologically relevant STEC strains, and in two animal models. Efficiency was first demonstrated in vitro on a collection of epidemiology relevant STEC strains where EB003 was able to efficiently kill E. coli strains harboring Stx genes. The EB003 CRISPR-based killing mechanism also abolished Shiga-toxin production, compared to antibiotic treatment, which can on the contrary lead to Shiga-toxin overproduction. Additionally, EB003 was able to reduce STEC colonization by multiple orders of magnitude in both a mouse gut colonization model and an infant rabbit disease model. In the latter model that recapitulates STEC infection associated symptoms, treatment with EB003 demonstrated statistically significant symptom alleviation.

The results provide strong support for further development of the company's CRISPR-Cas antimicrobial strategy and Eligobioticsplatform. Eligo is planning to initiate its first clinical trial for EB003 for the treatment of STEC in the second quarter of 2022.

About EB003

EB003, Eligo's lead drug candidate, was developed using the Company's proprietary Sequence-Specific Anti-Microbials (SSAM) platform. SSAM relies on the delivery of a non-replicative DNA payload encoding an exogenous Cas nuclease,guided towards specific genomic sequences. This modality leads to targeted lethal DNA double strand-breaks only if such sequences are present in the bacterial genome. This strategy enables precise engineering of the microbiome by killing only the strains harboring genomic sequences targeted by the nuclease.EB003 is being developed for the treatment of severe diarrhea induced by shiga-toxin (Stx) producing E. coli (STEC, leading to Hemolytic Uremic Syndrome) and is expected to enter Phase 1 in the second quarter of 2022. EB003 has been granted Orphan Drug Designation by the EMA.

About Eligobiotics

Eligobioticsis a first in class microbiome gene therapy that can change the microbiome composition and function with unprecedented precision.Eligobioticscan be designed, built, and optimized to target the microbiome species of choice with the automated proprietary platform that leverages Eligo's unique expertise in synthetic biology, phage biology, genetic engineering, and bioinformatics. Eligobioticscan be used to precisely and selectively remove unwanted bacterial strains carrying deleterious genes while leaving beneficial bacterial strains intact through the targeted delivery of a payload encoding an RNA-guided CRISPR-Cas nuclease. Alternatively, Eligobioticscan deliver to target bacteria the necessary genetic instructions to produce, display or secrete therapeutic proteins of interest in close proximity to the host's cells.Eligo is utilizing its Eligobioticsplatform to build a pipeline of drug candidates in inflammation, autoimmunity, and oncology.

About EligoBioscience

Eligo Bioscience is the world leader in microbiome gene therapy to address microbiome-associated diseases. Eligo was founded by scientists from The Rockefeller University, where CRISPR-based antimicrobials were invented, and by scientists from MIT. Eligo was named a Technology Pioneer by the World Economic Forum in 2017. With venture capital funding from Khosla Ventures and Seventure Partners, and non-dilutive funding from the GlaxoSmithKline, European Commission, CARB-X, and Bpifrance, Eligo has built an extensive pipeline of drug candidates using its Eligobioticsplatform.

Through its novel technology platform and robust intellectual property positions, Eligo is poised to be a catalyst for the growth anticipated across the microbiome-associated diseases industry.

For more information about Eligo visithttps://www.eligo.bio/.

Follow us athttps://www.twitter.com/EligoBioandhttps://www.linkedin.com/company/eligo-bio.

Logo - https://mma.prnewswire.com/media/1533529/Eligo_Bioscience_SA_Logo.jpg

Eligo Contact:

Argot PartnersKevin Murphy / Troy Neubeckereligo@argotpartners.com+1-212-600-1902

SOURCE Eligo Bioscience SA

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Looking at the stars, or falling by the wayside? How astronomy is failing female scientists – Space.com

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This article was originally published atThe Conversation.The publication contributed the article to Space.com'sExpert Voices: Op-Ed & Insights.

Lisa Kewley, Director, ARC Centre for Excellence in All-Sky Astrophysics in 3D, Australian National University

It will take until at least 2080 before women make up just one-third of Australia's professional astronomers unless there is a significant boost to how we nurture female researchers' careers.

Over the past decade, astronomy has been rightly recognized as leading the push towards gender equity in the sciences. But my new modeling,published in Nature Astronomy, shows it is not working fast enough.

Related: 20 trailblazing women in astronomy and astrophysics

TheAustralian Academy of Science's decadal planfor astronomy in Australia proposes women should comprise one-third of the senior workforce by 2025.

It's a worthy, if modest, target. However, with new data from the academy's Science in Australia Gender Equity (SAGE) program, I have modeled the effects of current hiring rates and practices and arrived at a depressing, if perhaps not surprising, conclusion. Without a change to the current mechanisms, it will take at least 60 years to reach that 30% level.

However, the modeling also suggests that the introduction of ambitious, affirmative hiring programs aimed at recruiting and retaining talented women astronomers could see the target reached in just over a decade and then growing to 50% in a quarter of a century.

Before looking at how that might be done, it's worth examining how the gender imbalance in physics arose in the first place. To put it bluntly: how did we get to a situation in which 40% of astronomy PhDs are awarded to women, yet they occupyfewer than 20% of senior positions?

On a broad level, the answer is simple: my analysis shows women depart astronomy at two to three times the rate of men. In Australia, from postdoc status to assistant professor level, 62% of women leave the field, compared with just 17% of men. Between assistant professor and full professor level, 47% of women leave; the male departure rate is about half that. Women's departure rates aresimilar in US astronomy.

Read more:'Death by a thousand cuts': women of color in science face a subtly hostile work environment

The next question is: why?

Many women leave out of sheer disillusionment. Women in physics and astronomy say their careers progress more slowly than those of male colleagues, and that the culture is not welcoming.

They receive fewer career resources and opportunities. Randomized double-blind trials and broad research studies in astronomy and across the sciences show implicit bias in astronomy, which means more men arepublished,cited,invited to speak at conferences, and giventelescopetime.

It's hard to build a solid research-based body of work when one's access to tools and recognition is disproportionately limited.

There is another factor that sometimes contributes to the loss of women astronomers: loyalty. In situations where a woman's male partner is offered a new job in another town or city, the woman more frequentlygives up her work to facilitate the move.

Encouraging universities or research institutes to help partners find suitable work nearby is thus one of the strategies I (and others) have suggested to help recruit women astrophysicists.

But the bigger task at hand requires institutions to identify, tackle and overcome inherent bias a legacy of a conservative academic tradition that,research shows, is weighted towards men.

A key mechanism to achieve this was introduced in 2014 by the Astronomical Society of Australia. It devised a voluntary rating and assessment system known as thePleiades Awards, which rewards institutions for taking concrete actions to advance the careers of women and close the gender gap.

Initiatives include longer-term postdoctoral positions with part-time options, support for returning to astronomy research after career breaks, increasing the fraction of permanent positions relative to fixed-term contracts, offering women-only permanent positions, recruitment of women directly to professorial levels, and mentoring of women for promotion to the highest levels.

Most if not all Australian organizations that employ astronomers have signed up to the Pleiades Awards, and are showing genuine commitment to change.

Seven years on, we would expect to have seen an increase in women recruited to, and retained in, senior positions.

And we are, but the effect is far from uniform. My own organization, the ARC Centre of Excellence in All-Sky Astrophysics in 3 Dimensions (ASTRO 3D), is on track for a 50:50 women-to-men ratio working at senior levels by the end of this year.

TheUniversity of Sydney School of Physicshas made nine senior appointments over the past three years, seven of them women.

But these examples are outliers. At many institutions, inequitable hiring ratios and high departure rates persist despite a large pool of women astronomers at postdoc levels and the positive encouragement of the Pleiades Awards.

Using these results and my new workforce models, I have shown current targets of 33% or 50% of women at all levels are unattainable if the status quo remains.

I propose a raft of affirmative measures to increase the presence of women at all senior levels in Australian astronomy and keep them there.

These include creating multiple women-only roles, creating prestigious senior positions for women, and hiring into multiple positions for men and women to avoid perceptions of tokenism. Improved workplace flexibility is crucial to allowing female researchers to develop their careers while balancing other responsibilities.

Read more:Isaac Newton invented calculus in self-isolation during the Great Plague. He didn't have kids to look after

Australia is far from unique when it comes to dealing with gender disparities in astronomy. Broadly similar situations persist in China, the United States and Europe. AnApril 2019 paperoutlined similar discrimination experienced by women astronomers in Europe.

Australia, however, is well placed to play a leading role in correcting the imbalance. With the right action, it wouldn't take long to make our approach to gender equity as world-leading as our research.

This article is republished fromThe Conversationunder a Creative Commons license. Read theoriginal article.

Follow all of the Expert Voices issues and debates and become part of the discussion on Facebook and Twitter. The views expressed are those of the author and do not necessarily reflect the views of the publisher.

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Astronomers discover largest known spinning structures in the universe – Space.com

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Tendrils of galaxies up to hundreds of millions of light-years long may be the largest spinning objects in the universe, a new study finds.

Celestial bodies often spin, from planets to stars to galaxies. However, giant clusters of galaxies often spin very slowly, if at all, and so many researchers thought that is where spinning might end on cosmic scales, study co-author Noam Libeskind, a cosmologist at the Leibniz Institute for Astrophysics Potsdam in Germany, told Space.com.

But in the new research, Libeskind and his colleagues found that cosmic filaments, or gigantic tubes made of galaxies, apparently spin. "There are structures so vast that entire galaxies are just specks of dust," Libeskind said. "These huge filaments are much, much bigger than clusters."

Related: The best Hubble Space Telescope images of all time!

Previous research suggested that after the universe was born in the Big Bang about 13.8 billion years ago, much of the gas that makes up most of the known matter of the cosmos collapsed to form colossal sheets. These sheets then broke apart to form the filaments of a vast cosmic web.

Using data from the Sloan Digital Sky Survey, the scientists examined more than 17,000 filaments, analyzing the velocity at which the galaxies making up these giant tubes moved within each tendril. The researchers found that the way in which these galaxies moved suggested they were rotating around the central axis of each filament.

The fastest the researchers saw galaxies whirl around the hollow centers of these tendrils was about 223,700 mph (360,000 kph). The scientists noted they do not suggest that every single filament in the universe spins, but that spinning filaments do seem to exist.

The big question is, "Why do they spin?" Libeskind said. The Big Bang would not have endowed the universe with any primordial spin. As such, whatever caused these filaments to spin must have originated later in history as the structures formed, he said.

One possible explanation for this rotation is that as the powerful gravitational fields of these filaments pulled gas, dust and other material within them to collapse together, the resulting shearing forces might have spun up this material. Still, right now, "we're not really sure what can cause a torque on this scale," Libeskind said.

The scientists now seek to understand the origin of filament spin through computer simulations of how matter behaves on the largest cosmological sales. The researchers detailed their findings online June 14 in the journal Nature Astronomy.

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UW astronomer redefines the scientific hero as part of The Great Courses – UW News

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Education | Profiles | Science | UW News blog

June 15, 2021

UW astronomer Emily Levesque delivers her course Great Heroes and Discoveries of Astronomy as part of The Great Courses, a popular online learning platform.The Teaching Company

If you look on Emily Levesques website, youll notice that one punctuation mark is prominent: the exclamation point. Classifying massive stars with machine learning! reads one blog post. Gravitational waves from Thorne-Zytkow objects! reads another.

My default state is exclamation point, said Levesque, an associate professor of astronomy at the University of Washington. When were talking about space and were talking about science, how could you not?

Now Levesque is bringing that enthusiasm to The Great Courses, an online learning platform offering classes to the general public on a range of topics, from playing guitar to decoding Egyptian hieroglyphics. Levesques course, Great Heroes and Discoveries of Astronomy, takes viewers on a tour of the biggest advancements in one of humanitys oldest sciences and the people behind them.

This course, which launched in February, came six months after Levesques popular science book on the history of observational astronomy, The Last Stargazers. The course consists of 24 lectures and covers the work of some scientists you may be familiar with, like Albert Einstein, Carl Sagan and Edwin Hubble, and others who might be new to you.

Those names include Henrietta Swann Leavitt. She was one of the Harvard computers, the team of women who processed astronomical data work made famous by the film Hidden Figures. Leavitts research on measuring the distances to stars laid the groundwork for Hubbles assertion that the universe is expanding. George Carruthers was an African American scientist who patented an ultraviolet camera and built the only telescope weve taken to the moon. Vera Rubin discovered dark matter; today an entire subfield of astrophysics is devoted to studying it. An enormous telescope in Chile is now named after her.

The course pokes at our idea of what a scientific hero is, Levesque said. Theres this stereotype that science is done by a white man alone in a room, coming up with an idea and then just spitting it out full formed into the universe.

This stereotype overlooks the collaborative nature of science, something Levesques course highlights. Breakthroughs can result from the efforts of a dozen scientists doing work that builds off each other over time, or from heroic efforts by teams of thousands. Levesque teaches a unit on the discovery of gravitational waves; the gravitational wave detector in Washington, part of the Laser Interferometer Gravitational-Wave Observatory, or LIGO, took thousands of people to build and takes thousands to maintain.

Levesque also broadens the definition of heroism to include acts like improving access to astronomy, making it more inclusive and bringing science literacy to the public.

One lecture tells the story of Frank Kameny, an astronomer in the U.S. Army Map Service. Months after he was hired in 1957, Kameny was fired when he refused to answer questions about his sexual orientation. He filed a lawsuit against the federal government, the first alleging discrimination based on sexual orientation in a U.S. court. Although it was unsuccessful, Kameny went on to become a leader in the fight for LGBTQ rights.

Its a really important time right now to remember that science is done by people, said Levesque. I dont think understanding science and understanding the human nature behind the discoveries we make has ever been more important. The human side of scientists cant be separated from the science that they do.

The human side of scientists not only affects their work, but it also shapes narratives around science. Stories we tell about scientific heroes and discoveries are often what makes science memorable. If the stories about people are interesting, then learning about the science will follow.

Levesque remembers, as a teen, reading the book A Man on the Moon: The Voyages of the Apollo Astronauts by Andrew Chaiken, about the early space program. She loved learning about the astronauts and the people in mission control. She was already a space geek, but reading about the fun they were having, identifying with them and seeing the creative problem-solving behind the science enabled her to picture what it would be like to work in astronomy.

Stories have the power to inspire or when the narrative is skewed or told from a singular point of view they can send a message about who does or doesnt belong. Thats why expanding the definition of a scientific hero beyond the stereotype is so important.

Levesque says her colleagues are a broad mix of people. They are ultramarathoners. They play in bands. They have a broad range of interests but have one thing in common: a love for space. More women are entering the field, but the low number of scientists from underrepresented groups like the Black and Latino communities shows there is still a ways to go when it comes to making astronomy more inclusive.

But if a broader range of stories are told, then more people will be able to envision themselves doing the work. And that will result in better science.

Its always worth reminding people when you talk about scientific heroism that you need heaps of people to do this work, Levesque said. Unique contributions can come from having a different perspective on a problem or other areas of expertise that a scientist can draw on. You need all sorts of talents and skill sets and enthusiastic folks who want to make science a part of their lives thats the ingredient, thats the way to do science.

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Astronomy Professor Develops Innovative Medical Imaging Device – The College Today

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As an astronomer whose research focuses on the imaging of extrasolar planets many light years away, Joe Carson spends a lot of time looking at distant celestial bodies. But his research and the imaging tools he and his team have created are grounded much closer to home. In fact, Carson credits the talent and skill produced right here at the College of Charleston for the development of medical imaging instrumentation that is now being used to look at human bodies on Earth.

Thats because his startup, Pensievision which primarily employs CofC alumni and students applies technologies from NASAs space telescopes to produce high-resolution 3D images using novel medical imaging instrumentation. The work includes their invention of the worlds first portable 3D colposcope to assist in early-stage detection of pre-cancer cervical lesions.

Over the past five years, everything that Pensievision has done has been enabled by students and alumni, who are the engine of the technologys development. Because of their work, we have been able to create this innovative and important device for doctors to use in any medical setting where imaging is used, says the associate professor of astronomy. My current projects long-term goal is to prevent cervical cancer deaths in some of the most underserved communities in the world, including those lacking medical infrastructure or even electricity.

Joe Carson and his startup, Pensievision, have created the worlds first portable 3D colposcope.

And, this spring, Carson was awarded a $400,000 National Institutes of Health (NIH) grant to make this a reality. Through the NIH Small Business Innovation Research (SBIR) program, Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings, the grant supports a 20-patient study of the 3D-imaging camera that Carson and his team created. The funding will allow Carson to travel to Kenya to meet with womens health leaders there and prepare for an intended follow-up patient study in sub-SaharanAfrica.

This grant will have far-reaching impacts and its all possible because of the CofC students and recent grads and all their hard work that has led up to this, says Carson. Theyve been creating new codes, designing and assembling devices, and applying software in novel ways.

The students and alumni even played a central role in creating the NIH grant application. And considering that the NIH review committee gave the proposal a perfect score they did a pretty great job!

A perfect score is unheard of Ive never seen one, Ive never heard of one, says Carson, explaining that usually a score of 40 indicates youve done really well, with 10 being perfect and 90 being poorest. When I saw the score of 10, I actually contacted the program administrator to see if there was an error. It just shows how innovative this technology is. Its a big jump from what we have now a huge paradigm shift. So, this shows that they see something really special and really valuable in this work.

As immense an impact that this technology might have across the world, Carson says its the impact that the work is having on the students and alumni that hes especially proud of.

It gives them experience with leadership and optical design lab testing, engineering, circuit boards and with FDA considerations, and that approval process, he says. Theyre not just learning the technology and the engineering, they get to learn about deploying these products. Theyre thinking about the consumer side of it: usability, scalability, aesthetics.

They also get to see the economics of it, Carson continues. They get to see how getting investor support is different than government support. They get to see how things all come together all the different angles, from design to diagnosis to make a difference in medical research from here to third world countries. These things are the future of medicine, so it puts them in an extremely strong position for imaging processing, artificial intelligence, data analyses and so on.

Junior astrophysics majorJenna Snead agrees that the independent research project she has done with Carson andPensievisionhas all sorts of applications including inthe astrophysics research that she plans to do after college.

While doing a medical imaging project seems way out in left field, astrophysics relies on a lot of the same imaging techniques, which will help me in any future astronomicalimaging projects, says Snead, who last semester won the School of Science and Mathematics Best of the Best Award, the Sigma Xi Best of the Best Award and the Department of Physics and Astronomy Best Poster Award for her research with Carson. Dr. Carson also often takes time to go into detail about how the concepts Im working with relate to my particular field, and to physics in general. Additionally, working with software and computer programming is indispensableto both grad school and any area of physics research, so getting familiar working with this projects code has been an amazing experience.

This summer Snead is working with circuits in an attempt to improve battery functionality and length of battery life, but her particular study of interest involves color analysis and how to best organize color channels to get the best image possible from the imaging wand.

This work is largely done on the software side. While this seems like a small project, it is important that we can get a clear image so that the future clinicians using it can diagnose as accurately as possible, she says. The coolest thing Ive learned inmy research so far is definitely how we actually process light and create images. Everything we perceive requires a different focal lengthwhich,when done manually (as we are doing with our 3D imaging),requires long lines of code. However, our brain does it automatically, every second of the day. Its just crazy when we think about how capable our brains are of processing the world around us.

Its these kindsof connections that make Carson so excited about what the College can inspire in its students and how valuable that is to the future workforce.

The College produces smart, creative, hardworking innovators. It provides a really good educational background and its graduates are bringing that education out into the world, he says. The students and graduates of the College really are the lifeline of Pensievision our number one resource.

In addition to producing a smart and skilled staff for Pensievision, the College has supported Pensievision through partnerships and grant applications, too.

Pensievision did not sprout up by itself it took a lot of support. And I cannot emphasize enough CofCs role in partnering to save lives and to create high paying jobs in the Lowcountry. Forming those partnerships has been invaluable, says Carson, adding that in recent years Pensievision has been among the top employers of students graduating from the Colleges Department of Physics and Astronomy. And as CofCs engineering program gets up and running in the next few years, I think that this partnership will continue to expand.

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‘Changing-Look’ Blazar Spotted 6.3 Billion Light-Years Away | Astronomy – Sci-News.com

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Astronomers have performed photometric and spectroscopic observations of B2 1420+32, a blazar with a collection of changing-look features.

Sloan Digital Sky Survey archival image from March 2004 (left) and the image from the observation campaign of B2 1420+32 taken by Mishra et al. in January 2020 using ASAS-SN (right); the blazars brightness increased by a factor of 100. Image credit: SDSS / Mishra et al., doi: 10.3847/1538-4357/abf63d.

Blazars are powerful active galactic nuclei (AGN) with relativistic jets pointing toward the observer.

Their jets span distances on the million light-year scales and are known to impact the evolution of galaxies and galaxy clusters in which they reside via the radiation.

These features make blazars ideal environments in which to study the physics of jets and their role in galaxy evolution.

Blazars are a unique kind of AGN with very powerful jets, said lead author Hora Mishra, a Ph.D. student in the Homer L. Dodge Department of Physics and Astronomy at the University of Oklahoma.

Jets are a radio mode of feedback and because of their scales, they penetrate the galaxy into their large-scale environment.

The origin of these jets and processes driving the radiation are not well-known. Thus, studying blazars allows us to understand these jets better and how they are connected to other components of the AGN, like the accretion disk.

These jets can heat up and displace gas in their environment affecting, for example, the star formation in the galaxy.

In the research, Mishra and her colleagues investigated the evolution of B2 1420+32, a blazar located 6.3 billion light-years away in the constellation of Botes.

At the end of 2017, this blazar exhibited a huge optical flare, a phenomenon captured by the All Sky Automated Survey for SuperNovae (ASAS-SN) telescope network.

We followed this up by observing the evolution of its spectrum and light curve over the next two years and also retrieved archival data available for this object, Mishra said.

The campaign, with data spanning over a decade, has yielded some most exciting results.

We see dramatic variability in the spectrum and multiple transformations between the two blazar sub-classes for the first time for a blazar, thus giving it the name changing-look blazar.

The astronomers concluded that this behavior is caused by the dramatic continuum flux changes, which confirm a long-proposed theory that separates blazars into two major categories.

In addition, we see several very large multiband flares in the optical and gamma-ray bands on different timescales and new spectral features, Mishra said.

Such extreme variability and the spectral features demand dedicated searches for more such blazars, which will allow us to utilize the dramatic spectral changes observed to reveal AGN/jet physics, including how dust particles around supermassive black holes are destructed by the tremendous radiation from the central engine and how energy from a relativistic jet is transferred into the dust clouds, providing a new channel linking the evolution of the supermassive black hole with its host galaxy.

We are very excited by the results of discovering a changing-look blazar that transforms itself not once, but three times, between its two sub-classes, from the dramatic changes in its continuum emission.

In addition, we see new spectral features and optical variability that is unprecedented. These results open the door to more such studies of highly variable blazars and their importance in understanding AGN physics.

It is really interesting to see the emergence of a forest of iron emission lines, suggesting that nearby dust particles were evaporated by the strong radiation from the jet and released free iron ions into the emitting clouds, a phenomenon predicted by theoretical models and confirmed in this blazar outburst, said Dr. Xinyu, also from the Homer L. Dodge Department of Physics and Astronomy at the University of Oklahoma.

The study was published in the Astrophysical Journal.

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Hora D. Mishra et al. 2021. The Changing-look Blazar B2 1420+32. ApJ 913, 146; doi: 10.3847/1538-4357/abf63d

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Astronomer Kelsey Johnson Reflects on the Science Behind the Search for UFOs – University of Virginia

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It was something not from the Earth, U.S. Navy Cmdr. David Fravor, commanding officer of a squadron of F/A-18 Hornet fighter planes, said in an interview with the Washington Post about the fast-moving, Tic Tac-shaped UFO he sighted during a 2004 training mission over the California coast. The object moved unlike any aircraft he was aware of and seemed to defy nearby radar operators efforts to track it.

Fravors account of the incident remained classified for 13 years until the Department of Defense announced the formation of the Unidentified Aerial Phenomena Task Force in 2017 and charged it with the job of cataloging and analyzing sightings of strange aerial objects that could potentially represent a threat to U.S. national security.

Late in 2019, lawmakers asked the secretary of defense and director of national intelligence to submit a report on what the task force has learned about the objects we know as UFOs, and an unclassified version of that report is scheduled to be released later this month.

Government officials have already confirmed that the task force has found no evidence of alien spacecraft, but University of Virginia astronomer Kelsey Johnson, who is president-elect of the American Astronomical Society and also a former member of the National Science Foundations Astronomy and Astrophysics Advisory Committee, spoke with UVA Today about what the report might contain and what it might mean for those of us who are eager to catch a glimpse of extraterrestrial life.

Q. What do you think the governments report on UFO activity is most likely going to tell us?

A. I think the report is likely to confirm that there have been sightings of objects in the sky that are currently unexplained. The catch is that just because something is unidentified does not mean that it was extraterrestrial life visiting Earth. If you are really bad at identifying things, then anything in the sky could technically be a UFO.

Taking the step to infer that the object is extraterrestrial in origin requires evidence and in science we have a saying that extraordinary claims require extraordinary evidence. Finding evidence for extraterrestrial life would pretty much peg the meter on extraordinary.

That being said, regardless of the origin of objects in UFO sightings, I think these occurrences can be important to study and understand. Objects that have been observed by reliable witnesses and recorded to behave in unexplained ways absolutely merit legitimate scientific effort. Even if the explanation isnt aliens, we might gain new insight into a natural phenomenon or better understand threats to national security. I find it really unfortunate that so much stigma has become attached to this topic among both scientists and government officials. Yes, be skeptical and require evidence, but also be open-minded to explanations you cannot rule out.

This stigma has actually spun off a new term with less baggage: Unidentified Aerial Phenomena, or UAP.

Q. What kinds of phenomena are most likely reported as UFOs or UAP?

A. This depends on who is doing the reporting! For the general public, one of the underlying issues is that many people simply dont spend a lot of time outside looking at the sky, so folks are not so familiar with objects that are totally normal. As a result, Venus, Mars and even the moon are frequently reported as UFOs. But there are also a number of less-common, but still 100% explainable, atmospheric phenomena that can appear pretty strange if you dont know about them everything from sun dogs caused by ice crystals in the atmosphere to really funky clouds. Lenticular clouds can do an especially great job mimicking Hollywood-style flying saucers.

Things get much harder to explain when there appear to be changes in motion that defy known modern technology. This is what has raised some eyebrows with the recent reports by the military. I am reminded of the god of the gaps fallacy, which is to say that just because we dont understand something doesnt mean the explanation is supernatural or alien.

Q. What might make some of these phenomena appear to be something other than what they are?

A. Human perception is fraught with issues and is extremely unreliable, and the need to be skeptical of personal accounts is amplified when something isnt reproducible. We are also incredibly bad at gauging distances. If we dont really know how far away something is, changes in motion are easily misinterpreted by our brains. For these reasons and others, it is essential to have actual data and measurements to test against different hypotheses.

Q. Are there good reasons for using federal or military funding for further research into these sightings?

A. I think it is always worthwhile to study things we dont understand. That is how we make progress toward understanding the universe we live in. Truly unexplained phenomena with associated data should not be sitting on a shelf these could reveal something very cool about the natural world or a novel technology that could be beneficial or threatening.

Q. How could science benefit from a renewed interest in extraterrestrial visitors?

A. Science is all about curiosity, and thinking about extraterrestrial life is rich ground for asking a huge range of questions. I absolutely love talking about and teaching these questions as a hook for inquiry what forms might extraterrestrial life take? What environments might they need to live? How would they communicate? Would they even want to communicate? Considering these questions also gives us insight into ourselves and our own place in the universe.

Q. What is the likelihood that aliens have, in fact, visited Earth?

A. The likelihood that extraterrestrial life has visited Earth depends on a number of assumptions. Im not going to give a specific likelihood, but I will say that with some basic assumptions, one could infer that the universe ought to be teeming with life.

Now whether extraterrestrial life is commonly able to survive and evolve into something more than a simple organism let alone develop technology and travel across the galaxy is the crux of the matter. Answering these questions goes beyond astrophysics and astrobiology into fields that dont exist yet like astrosociology and astropsychology.

Q. What kind of proof would scientists in those fields need to be sure?

A. To prove extraterrestrial life had visited Earth would require us being able to unequivocally rule out terrestrial origins, and that is tough. To prove something in the scientific sense, the phenomenon generally has to be repeatable so that hypotheses can be tested. With only fleeting and unpredictable sightings, it is virtually impossible to test hypotheses to verify or dismiss them. This leaves us wanting for real, tangible, physical artifacts that can be examined and tested by a range of scientists.

The late Arthur C. Clarke had three adages known as Clarkes Three Laws the first of which was, When a distinguished but elderly scientist states that something is possible, he [sic] is almost certainly right. When he [sic] states that something is impossible, he [sic] is very probably wrong. We would all do well to use the word impossible with caution.

Q. How would you feel if extraterrestrial life were discovered?

A. I would be elated. If there is no other sentient life in the galaxy, that is a huge warning sign for humans and our potential for long-term survival. And how sad it would be for this enormous and grand universe to have so few to bear witness. I also think that finding other sentient life would bring about a beautiful renaissance of human thought and knowledge. I have to believe that our worldviews would change for the better if we had a deeper understanding that we are all truly on this tiny little planet together.

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3.3-Billion-Light-Year-Long Arc of Galaxies Discovered | Astronomy – Sci-News.com

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An international team of astronomers from the United States and the United Kingdom has made the discovery of a giant, almost symmetrical arc of galaxies by looking at absorption lines in the spectra towards quasars from the Sloan Digital Sky Survey (SDSS).

The Giant Arc: the gray contours represent the Mg II absorbers, which indicate the distribution of galaxies and galaxy clusters; the blue dots represent the background quasars; the Giant Arc is centered on this figure spanning -600 to +400 Mpc on the x-axis. Image credit: Lopez et al.

The newly-discovered arc of galaxies is located more than 9.2 billion light-years away in the constellation of Botes.

Named as the Giant Arc, it spans approximately 3.3 billion light-years in length and 330 million light-years in width.

The structure is twice the size of the striking Sloan Great Wall of galaxies and clusters that is seen in the nearby Universe.

Its discovery adds to an accumulating set of cautious challenges to the Cosmological Principle.

The growing number of large-scale structures over the size limit of what is considered theoretically viable is becoming harder to ignore, said Alexia Lopez, a Ph.D. student in the Jeremiah Horrocks Institute at the University of Central Lancashire.

According to cosmologists, the current theoretical limit is calculated to be 1.2 billion light-years, which makes the Giant Arc almost three times larger.

Can the Standard Model of cosmology account for these huge structures in the Universe as just rare flukes, or is there more to it than that?

Lopez and colleagues made the discovery by observing the intervening magnesium (Mg) II absorption systems backlit by quasars, which are remote super-luminous galaxies that emit extraordinary amounts of energy and light.

A quasar acts like a giant lamp shining a spotlight through other galaxies, with the light eventually reaching us here on Earth, Lopez said.

We can use telescopes to measure the spectra of these quasars, which essentially tells us the journey that the quasar light has been through, and in particular where the light has been absorbed.

We can locate where the quasar light has passed through galaxies by a signature Mg II doublet feature, which is a distinctive pair of absorption lines in the spectra.

From this easily identified absorption fingerprint, we can map low luminosity matter that would usually go unseen due to its faint light emitted in comparison to the quasars.

When viewed on such a large scale, we expect to see a statistically smooth distribution of matter across the Universe, based on the Cosmological Principle introduced by Einstein to make the maths easier, that the Universe is isotropic and homogeneous.

It means that the night sky, when viewed on a sufficiently large scale, should look the same, regardless of the observers locations or the directions in which they are looking.

The Giant Arc we are seeing certainly raises more questions than answers as it may expand the notion of sufficiently large. The key question is, what do we consider to be sufficiently large?

We are seeing the Giant Arc now, but in reality, the data were looking at show the Universe as it was half its lifetime ago because the light has been en route, traveling towards, us for billions of years. It was so long ago that the Universe at the time was about 1.8 times smaller than it is now.

The astronomers presented the results this month at the 238th virtual meeting of the American Astronomical Society (AAS).

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A.M. Lopez et al. 2021. A Giant Arc on the Sky. AAS 238, abstract # 111.01

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Texas A&M astronomer weighs in on upcoming UFO report – Times Record News

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Texas A&M University astronomer Nick Suntzeff has been involved with space research for 30 years and spent 20 years in Chile, where he helped co-discover dark matter. Below, he offers his thoughts about UFOs and whether or not we are alone in the universe.

The New York Times and CNN reported a government report on "UFOs" does not provide evidence of aliens, but also doesn't rule the possibility out. USA TODAY

Q: What can we expect from the governments official UFO report?

A: I have no idea what the report will say, but I doubt they have any evidence where a UAP (Unidentified Aerial Phenomenon, previously called a UFO) is clearly resolved. For starters, have you ever noticed that UAP images and videos are usually out of focus?

In the recent videos that are now getting a lot of attention called FLIR1, Gimbal, Triangle, and GoFast, for instance, lets consider the triangular UFO. In the video you can also see other objects that are triangles. Are these sister UFOs? No. What this means is that the camera was out of focus and the camera pupil (shutter) was triangular. One person has measured the positions of the faint triangles (and one bright one) and shown that they are at the positions of the stars near the constellation Taurus and the planet Jupiter. Also, this UFO blinks in the same way a commercial aircraft does. It was taken off the coast of Los Angeles where there are lots of air traffic. It is an out-of-focus video taken with an infrared camera.

UFOs, or unidentified flying objects, have stirred our imagination for generations. Sightings of these alleged interstellar visitors to Earth have been chronicled throughout history. However, the mania for UFOs shifted into hyperdrive in 1947, when flying saucer enthusiasts believed the remains of an otherworldly spacecraft, and even the corpse of an alien, were discovered in Roswell, New Mexico.(Photo: ursatii / Getty Images)

This is one example of an explanation that fits the data. Now, why did the Navy not provide this explanation? They should have asked an astronomer before releasing the video because they could have quickly shown that this an out of focus image.

Q: So does that mean the UFOs are not real?

A: Well, you can often debunk one story, but you will then get another story and someone will say, okay, but explain this one.

In one video, a pilot said the UFO resembled a large Tic Tac mint and that it was defying the laws of physics over the ocean and moving fast. The problem here is that we dont know how far away it was. If it was high above the ocean, then the apparent motion is likely due to the airplane and not the object.

This is called parallax. You can often find answers like this, and so on.

So I am not optimistic that we will be shown extraordinary evidence where there is no natural explanation for what is seen.

Q: So you are saying that you can rule out most UFO sightings as something else and not a UFO?

A:There are often simple, but boring answers. For example, the most common UFO is the planet Venus. Once I got a phone call from an excited person who was telling me they can see a UFO right now. It is moving back and forth, and sometimes it suddenly comes closer and then moves away. I asked them if they could still see it. Yes! So I drove down to the parking lot and there was a group of people bunched together pointing up to the sky. I went over there and asked them to show me where it is. I look up there, and it is Venus. I tell then it is Venus. I look at it and it is not moving. It was twinkling a bit but otherwise, nothing unusual. As we looked, they admitted it was not moving, but I was assured that it was before I got there.

Q: Many people are convinced that these UFOs are visitors from another planet, that they have been monitoring the Earth for decades and they are real. If true, it would be perhaps the biggest story of all time. Is it possible?

A:I cant rule out we have visitors from other planets. But we need clear evidence. We need a clear photo for instance. So far, we do not have such evidence.

Note that many reports say that the UFO object was a certain size and moving at a certain speed. Now, if you dont know what the object is, you cant know how far away it is, or how big it is. Anyone who says they know the size (unless it landed and left a mark) is, well, not understanding simple optics. So once again, we need clearer proof. I have seen lots of weird things in the sky very weird things but I can always explain them.

As for intelligent life in a way it is a strange question. As the great physicist Enrico Fermi was claimed to have said, Well, where are they? That is, if there is intelligent life, why dont we see it with our telescopes, or see evidence here on Earth of visitations? Astronomers are always looking for life elsewhere in the universe.

Congress-sanctioned UFO report to be released in June 2021.(Photo: U.S. NAVY)

Q: Any shred of truth to the long-held rumors that the government has been hiding pieces of crashed UFOs and perhaps even bodies?

A: If they do, this is the best kept secret ever. Our government is not great at keeping secrets, and this one would be a doozy. No, I dont believe there is any physical evidence. I dont think intelligent civilizations could travel the thousands of light years to the earth, and then crash their spacecraft. If they can travel that distance, I seriously doubt they would be this careless.

Q: It seems like the scientific community has always been more than a little reluctant to talk about UFOs. Why is that?

A: We are not reluctant to talk about it. There are a number of astronomers actively looking for signs of intelligent life out there. It is a real field in astronomy. The problem is that one cannot get government funding to study UFOs. So those astronomers look to the private sector to do the studies. A very close friend of mine, now retired, built his own observatory and is searching for intelligent signals. He got this funded by some rich person in Silicon Valley. If there were sources of steady funding, I am sure a lot of young astronomers would take a job searching for intelligent life.

Q: Any other thoughts you may have about UFOs?

A: . This is thought experiment. We are not too far maybe 100 years or so from building mini-satellites, accelerating them up to 10% the speed of light using lasers, and sending them off to nearby stars. We could make billions of them after all, we have made billions of cell phones so far. With laser acceleration and light-weight satellites (10 grams or so), we could launch these to billions of stars. The satellite could have a radio transmitter beeping the first 10 Fibonacci numbers (numbers used to create a mathematical sequence) showing it must be artificial.

If I can imagine this future technology which is not far from what we have today, the question is, why is there no satellite from another civilization that has passed this way, and beeped at us?

The only fact we are certain of is that so far -- and we are looking hard -- it is silent out there.

Texas A&M University astronomer Nick Suntzeff has been involved with space research for 30 years and spent 20 years in Chile, where he helped co-discover dark matter.(Photo: Contributed photo)

By Keith Randall, Texas A&M University Division of Marketing & Communications

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