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Daily Archives: May 27, 2021
CBD: Safe and effective? – Mayo Clinic
Posted: May 27, 2021 at 8:02 am
A prescription cannabidiol (CBD) oil is considered an effective anti-seizure medication. However, further research is needed to determine CBD's other benefits and safety.
CBD is a chemical found in marijuana. CBD doesn't contain tetrahydrocannabinol (THC), the psychoactive ingredient found in marijuana that produces a high. The usual CBD formulation is oil, but CBD is also sold as an extract, a vaporized liquid and an oil-based capsule. Food, drinks and beauty products are among the many CBD-infused products available online.
Currently, the only CBD product approved by the Food and Drug Administration is a prescription oil called Epidiolex. It's approved to treat two types of epilepsy. Aside from Epidiolex, state laws on the use of CBD vary. While CBD is being studied as a treatment for a wide range of conditions, including Parkinson's disease, schizophrenia, diabetes, multiple sclerosis and anxiety, research supporting the drug's benefits is still limited.
CBD use also carries some risks. Though it's often well-tolerated, CBD can cause side effects, such as dry mouth, diarrhea, reduced appetite, drowsiness and fatigue. CBD can also interact with other medications you're taking, such as blood thinners.
Another cause for concern is the unreliability of the purity and dosage of CBD in products. A recent study of 84 CBD products bought online showed that more than a quarter of the products contained less CBD than labeled. In addition, THC was found in 18 products.
If you plan to use products containing CBD, talk to your doctor.
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Can CBD Oil Be Used As An Antifungal? – nativenewsonline.net
Posted: at 8:02 am
Details
CBD skin care marketing has been booming lately. According to a study, this market is expected to reach an incredible $1.7 billion by 2025. Its only logical to see more and more skincare and beauty products containing CBD, from glow and body oils to face creams and facial serums.
Since there is an array of powerful CBD oil products for treating skin conditions, its time to tap into the many benefits that these products can offer.
The CBD compound is incredibly rich in anti-inflammatory properties and antioxidants, potentially effectively treating a range of skin-related conditions and issues. However, CBD can also be highly effective when used for treating more complex and severe conditions, like eczema and psoriasis.
Strong CBD oil contains powerful anti-inflammatory properties that can effectively mitigate skin irritation caused by inflammation. Cannabinoids are especially rich in omega-3 and omega-6 fatty acids that can do wonders to boost your skins overall health.
Nowadays, topical formulations based on cannabinoids contain GLA or gamma-linolenic acid, a proven compound for restoring proper skin moisturization. If you have a skin inflammation problem, applying a topical CBD solution might help provide relief.
CBD products, especially CBD oils, can be potentially effective in treating various conditions. With that in mind, lets focus on how to use CBD oil as an antifungal treatment solution.
CBD oil can potentially be a powerful antifungal treatment solution. A 2011 study showed the potential antifungal properties of CBD oil. The cannabis Sativa plant is rich in antifungal agents, and these specific compounds are cannabichromene (CBC) and cannabigerol (CBG).
CBD is, in its essence, an atomic composition of one oxygen and one hydrogen atom, and as such, it contains many antifungal properties. Its atomic compounds are quite effective against other molecules that undergo oxidation due to containing oxygen.
When CBD comes across fungi cells, it oxidizes them, rendering them incapable of multiplying and expanding. More importantly, CBD inhibits ergosterol and oxidizes the cells, thus preventing fungi from growing and spreading.
CBC, CBG, and CBD all attack fungi cells in an organized manner to kill the cells by destroying the cell membranes, preventing ergosterol production necessary for the growth of fungi. Without their nutrients, fungi cells cant thrive, and they eventually die.
Aside from all that, CBD also possesses properties to give other antifungal compounds a boost, most notably, caryophyllene oxide the most potent and naturally occurring terpene. All three hemp-derived compounds, CBC, CBG, and CBD, can potentially help increase the potency of this amazingly powerful antifungal terpene.
CBD has both antibacterial and antifungal properties that can be amazingly medicinal, effective, and therapeutic. Hemp-derived terpenes are lipophilic a property that makes them highly effective antifungals.
To understand how to treat fungal skin infections with CBD oil, we must first understand the symptoms and types of fungal infections. The most common symptoms of a fungal infection include:
The most common types of fungal skin infections are:
Full-spectrum CBD oils or oils that contain terpenes and all three cannabinoids we mentioned earlier are the most effective treatment against fungal infections. They have more powerful antifungal properties and are proven to kill fungi cells quite effectively.
You can start treating your fungal infection by adding full-spectrum CBD oil to your skincare regimen. CBD oils can produce the so-called entourage effect, which refers to a more powerful effect of your treatment due to other cannabinoids present in your CBD oil-based treatment.
When all three cannabinoids team up with terpenes, the CBD compounds travel faster through your bloodstream, providing a full range of benefits for your skin. Apply your CBD oil topically on regions with a fungal infection. If your condition is more severe, you can also consider taking CBD oil both orally and topically for more bioavailability and faster results.
To conclude, here are a couple of quick tips to help you with that.
The best way to prevent fungal infections but a wide range of skin conditions is to maintain proper and regular hygiene to keep your body clean.
Make sure your moist and warm areas of the body are always clean to avoid fungal infections.
Your overall body hygiene greatly depends on the quality and intensity of the products you use to keep your body clean.
Before you do anything to start treating your fungal infection, you should first consult a doctor and take their advice on how to proceed with alternative treatments like CBD oil.
Links:
https://www.webmd.com/vitamins/ai/ingredientmono-805/gamma-linolenic-acid-gla
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165946/
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Can CBD Oil Be Used As An Antifungal? - nativenewsonline.net
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WVU Today | As CBD oil sales hit the gas, WVU researcher studies its effects on driving performance – WVU Today
Posted: at 8:02 am
The market for CBD oil has grown faster than scientists knowledge of its effects. Toni Rudisilla researcher with the WVU School of Public Healthis recruiting participants for a study into how CBD oil influences driving ability. Participants will take either CBD oil or a placebo before using a driving simulator. Rudisill and her colleagues will see if driving performance differs significantly between the two groups. (WVU Photo/Morgan Goff)
People have been driving under the influence of alcohol since before the first person crank-started a Ford Model T. But CBD oil didnt become a concern until years after people began driving the Tesla Model X.
The widespread use of CBD oil is so new that scientists dont yet understand all of the ways it affects drivers. Toni Marie Rudisilla researcher with the West Virginia University School of Public Healthis recruiting participants for a new study into whether and how CBD oil impairs driving ability.
We dont really know much about CBD, said Rudisill, a research assistant professor in the Department of Epidemiology and Biostatistics. Theres not a whole lot of research on it. But there were all these anecdotal reports of people using it to help them sleep or help them relax. And as an injury epidemiologist, my first thought was, OK, then: if its making you tired, how does that impact your performance or make you more prone to injuries?
The studyfunded by the West Virginia Clinical and Translational Science Institutewill involve 40 participants. Half will be given 300 mg of pure CBD oil; the other half will receive a placebo. Because the study is double blind, neither the participants nor the researchers will know who has received the real or placebo doses.
We flavor the doses with peppermint oil to mask the difference in taste between the CBD oil and the placebo, Rudisill said. That way, people dont know what theyve gotten.
After taking their assigned dose, participants will complete a driving simulation that takes about half an hour.
The driving simulator doesnt look impressiveit looks like a regular old computer gamebut its amazing what it captures on the back end, Rudisill said.
For example, the simulator can show how often a participant drifts out of their lane, whether they use turn signals appropriately and whether they stop at stoplights. If a participant is waiting to turn left at an intersection, it can reveal whether they properly judge the speed and distance of oncoming cars. If a pedestrian darts into the road, it can identify whether the participant brakes in time.
What makes the simulator really great is that it provides a safe environment for people to drive in and where we can still assess performance, Rudisill said.
She and her colleagues will measure the participants driving performance and compare it between the two groups.
In addition, the researchers will assess the participants mood, drowsiness, sedation, reaction time and cognitive function at two points: before taking the CBD oil or placebo, and after finishing the driving simulation.
Were looking to see if their mood changes. Do they feel more tired? Will we see any cognitive changes that are maybe due to drowsiness? Rudisill said. Were interested to see how those variables relate to the driving measures. We drive every day, but driving is a complex task, right? Every single sense if involved.
CBD oil and related products have proliferated the marketplace because the 2018 Farm Bill removed hemp from the definition of marijuana under the Controlled Substances Act.
Now its everywhere, Rudisill said. If you really stop and look when you go to the grocery store, youll see so many CBD or hemp-infused products. Food products, animal productsyou name it. Its in everything. But we really dont know a whole lot about it yet.
Studies like hers are important because CBD sales probably wont let off of the gas pedal anytime soon. For example, MarketWatchpublished by Dow Jones & Co.predictsthat the global CBD market will experience a compound annual growth rate of 33.5% from 2021 through 2026.
The CBD oil thats available over the counterlike every other nutraceutical out thereisnt regulated by the FDA, Rudisill said. Theres not a whole lot of research out there about whether it really works or doesnt. Who knows what the dosage is or if it does anything? Who knows what dose you should use? People like me who have an interest in this have to see what it does to us.
Rudisill is actively recruiting participants for her study. Potential applicants should contact the studys coordinator, Cynthia Fisher-Duda, at cynthia.fisherduda@hsc.wvu.edu or 304-581-1923.
Research reported in this publication was supported by the West Virginia Clinical and Translational Science Institute. WVCTSI is funded by anIDeA Clinical and Translational grant from theNational Instituteof General Medical Sciences, under Award Number U54GM104942, to support the mission of building clinical and translational research infrastructure and capacity to impact health disparities in West Virginia.The content is solely the responsibility of the authors and does not necessarily represent the official views of NIH or CTSI.
-WVU-
see/05/25/21
CONTACT: Nikky LunaDirector, Communications and MarketingWVU School of Public Health304-293-1699;nikky.luna@hsc.wvu.edu
Call 1-855-WVU-NEWS for the latest West Virginia University news and information from WVUToday.
Follow @WVUToday on Twitter.
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CBD Oil Market is Expected to Grow at an Impressive CAGR by 2028 The Manomet Current – The Manomet Current
Posted: at 8:02 am
To conduct research and analysis, and deliver accurate and reliable forecasts on all global markets, a DBMR team of experts and professionals from various streams and verticals bring along crucial tried-and-tested skills, approaches, and techniques. CBD Oil Market report is spread across several pages and provides newest industry data, market future trends that allows identification of the products and end users driving revenue growth and profitability. The comprehensive business report analyses and examines the important industry trends, market size, market share estimates, and sales volume with which businesses can guess the strategies to increase their return on investment (ROI).
All the data and information gathered in the reliable CBD Oil Market report is studied and analysed with the demonstrated tools and techniques such as SWOT analysis and Porters Five Forces analysis. This world class report also provides the company profile, product specifications, production value, contact information of manufacturer and market shares for company. With the study of competitor analysis, businesses get knowhow of the strategies of key players in the market that includes but are not limited to new product launches, expansions, agreements, joint ventures, partnerships, and acquisitions. The large scale marketing report emphasizes on changing dynamics, growth-driving factors, restraints, and limitations.
Global CBD Oil Market, By Source (Organic and Conventional), Product Type (Marijuana Based, Hemp Based), Application (Multiple Sclerosis, Depression and Sleep Disorders, Neurological Pain, Others), (Country (U.S., Canada, Mexico, Germany, Italy, U.K., France, Spain, Netherland, Belgium, Switzerland, Turkey, Russia, Rest of Europe, Japan, China, India, South Korea, Australia, Singapore, Malaysia, Thailand, Indonesia, Philippines, Rest of Asia- Pacific, Brazil, Argentina, Rest of South America, South Africa, Saudi Arabia, UAE, Egypt, Israel, Rest of Middle East & Africa), Industry Trends and Forecast to 2027
CBDoil market is expected to witness growth at a rate of 31.90% for the forecast period of 2020 to 2027. CBD oil market report analyses the growth, which is currently being owed to the focus of unconventional application of hemp extract and CBD oil for medical purposes.
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The major players covered in the CBD oil market report are Dr. Hemp Me., QC Infusion, Hemp Production Services, Hudson Valley Hemp, LLC., Green Roads, Royal CBD, Moon Mother Hemp Company, CBD Oil Europe, King CBD, FOLIUM BIOSCIENCES, CV Sciences, Inc., Pharmahemp d.o.o., Gaia Botanicals, LLC, Canazil, Kazmira, Spring Creek Labs, Cavendish Nutrition Fulfillment LLC, Isodiol International Inc, HempLife Today, Hemp Oil Canada Inc, Medical Marijuana, Inc., among other domestic and global players.
CBD oil market is growing owing to certain reasons likely increasing frequency of psychical dysfunctions, inflation in assent ofhemp oilinfused commodities, progressing legalization in the farming of industrialized hemp, expanding utilization in individual care, and food & refreshments commodities, and progressing amount of chronic disorders. Some of the circumstances may act as the restraint for the market such as complicated administrative formation for the acceptance of industrialized hemp and the dearth of procurement of seeds for the agriculture use of hemp. To overcome certain hindrances innovative merchandise improvements from industrialized hemp will act as the opportunity for the market.
Competitive Landscape and CBD Oil Market Share Analysis
CBD oil market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies focus related to CBD oil market.
Global CBD Oil Market Scope and Market Size
CBD oil market is segmented on the basis of source, product type and application. The growth amongst the different segments helps you in attaining the knowledge related to the different growth factors expected to be prevalent throughout the market and formulate different strategies to help identify core application areas and the difference in your target markets.
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CBD Oil Market Country Level Analysis
CBD oil market is analysed and market size, volume information is provided by country, source, product type and application as referenced above.
The countries covered in the CBD oil market report are the U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.
North Americais anticipated to behold the most substantial percentage of CBD oil market due to the constituents such as legalization ofcannabisin many nations of the U.S. and the mounting knowledge regarding the advantages of CBD oil.
The country section of the report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points such as consumption volumes, production sites and volumes, import export analysis, price trend analysis, cost of raw materials, down-stream and upstream value chain analysis are some of the major pointers used to forecast the market scenario for individual countries. Also, presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.
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Summer Means a Return to Activity, and Time for Cibadol Products – PRNewswire
Posted: at 8:02 am
COLORADO SPRINGS, Colo., May 26, 2021 /PRNewswire/ -- After months of quarantine and inactivity, we're heading into the Memorial Day holiday and the official start of the summer season. For many of us, getting out in the post-COVID world this summer will mean an end to being cooped up and a return to an active lifestyle; which might also mean more scrapes, sunburn and sore muscles.
A recent studyreported that a growing number of consumers started using cannabidiol (CBD) products during the COVID-19 pandemic. That increase in usage has coincided with a years-long and a rapidly rising trend of CBD becoming more acceptable and mainstream for much of the American public.
This summer is also a good time for consumers to become acquainted or reacquainted -- with Cibadol (CY-buh-dol), one of the most potent, cost-efficient and highest-quality brands of CBD products available.
"We've been growing, harvesting, processing our own top-of-the-line hemp, and manufacturing our CBD products since 2015," said Andy Rodosevich, CEO of Hemp Depot, the parent company of Cibadol. "We bring a lot of experience to our CBD brands, and have a mission of presenting the best-possible products at the best possible price sometimes costing 50% less than what our competitors offer."
Along with years of experience, Cibadol controls its entire supply chain. Starting with its Colorado-grown hemp, cultivated under organic standards, the company is vertically integrated and uses automated manufacturing lines to keep its overhead low.
"From our innovative drink tablets to our gummie bears, roll-on muscle gel, and THC-free salve, we're excited to make available CBD products that everyone can afford," said Rodosevich. "We're not a startup that doesn't know what it's doing, and we're not like some companies that haven't even bothered to try and make their prices affordable. Cibadol brings to the CBD market the potency, quality and traceability consumers expect and demand."
The Cibadol line of products is available online in all 50 states. Read more about Cibadol at https://www.cibadol.com
About Hemp Depot - At Hemp Depot, Pure Starts Here. Hemp Depot is one of the largest providers of the highest-quality hemp CBD oil products, seed and clones in the U.S., proven with third-party testing. Because of Hemp Depot's commitment to purity and strength, our consumer and wholesale customers receive the best full-spectrum and 100% THC-free CBD products on the market, all grown, formulated and processed entirely in our facilities in Colorado.
Hemp Depot is one of the nation's largest and most trusted hemp brands specializing in seed genetics, planting, harvesting, formulating, wholesaling, and retailing cannabis for CBD under a variety of best-selling labels, as well as white labels for humans and pets. For more information visit https://hempdepotco.com/
SOURCE Hemp Depot
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Summer Means a Return to Activity, and Time for Cibadol Products - PRNewswire
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Well Care Botanicals CBD Topicals: Our Review – Ministry of Hemp
Posted: at 8:02 am
One of the crucial uses of cannabinoids, apart from recreation, is pain relief. Safely extracted cannabinoids make for some of the most effective and healthy pain-relief agents. And, though you can use cannabinoids in several ways to get rid of that unbearable joint or muscle pain, topicals are best for the purpose.
For one thing, they are discrete and easy to use. Secondly, you can apply them to the exact spot thats bothering you, without worrying about the consequences for your entire body. Third, because of the targeted application, the effect is specific to the location of the pain.
Topicals come in many forms, such as creams, gels, roll-ons, sprays, and even skincare products, such as lotions and lip balms.
But when it comes to topicals for pain relief, one company that you can trust without a sweat is Well Care Botanicals.
Its pain relief topicals certainly give us the impression that they Care!
In this blog, well review some of the brands best topicals.
So, read on
Perhaps the best thing about Well Care Botanicals is that it was founded by a doctor. Once you know that, your trust goes up a notch, doesnt it?
As the brand clarifies on its website, the teams target is to help customers achieve greater health and wellness and enjoy a better quality of life.
Well Care Botanicals line of products is proof enough of its goals.
The product range comprises gel capsules, pain creams and gels, skincare products, tinctures, and pet productsitems you would associate with health and wellness and not recreation.
But, are the products effective?
The proof of the pudding is in the eating.
However, what went into the pudding and how it was made can give a fair idea as well. So first, lets get into that first.
Based out of Beachwood, New Jersey, Well Care Botanicals sources its hemp from licensed farms in the US. Although the exact location hasnt been provided by the brand, the website mentions that the hemp is farmed sustainably and organically.
The firm uses the CO2 method to derive extracts from hemp. It uses broad-spectrum hemp in its products. That is, the extracts contain natural cannabinoids, terpenes, and flavonoids but no tetrahydrocannabinol (THC).
Well Care Botanicals uses only all-natural ingredients in its products. Apart from broad-spectrum hemp extracts, the products contain a host of plant-based oils and extracts and zero additives.
Well Care Botanicals gets all its products tested by Desert Valley Testing labs. You can get the individual Certificates of Analysis and the Lab Purity Results on every product page.
Looking at the customer reviews, Well Care Botanicals seems to be a stellar performer. Most of the products have got nothing but five stars from customersboth on the brand website and third-party sites. Only a handful of customers have complained that the pain cream was just about okay and did not work any wonders.
The companys production processes are GMP-certified.
The brand website is easily navigable and user-friendly. There is a blog section to answer some of the key questions customers may ask. The product pages are comprehensive and contain all crucial info, including ingredients and CoAs.
The company has moderately friendly customer policies. Shipping is free for orders over $75. The company ships orders within 2-3 business days, barring weekends and holidays. However, the customer has to bear the tariffs and taxes, if any, levied on the shipped order.
The company doesnt accept responsibility for damages to orders during transit or lost shipments. For damaged products, you have to contact the shipping firm and seek damages.
However, the brand does offer a 14-day money-back guarantee on sealed items that are returned in their original packaging. But that does not include the shipping charges.
As per industry standards, youre required to contact the brands customer service before sending back the order/item and fetch a Return Merchandise Authorization number. You will need to pen it down on the package that youll be returning.
If the brand finds the merchandise in satisfactory condition, it will initiate your refund within 24 hours of receiving the package.
We have chosen three topical products from the brand for this review. These are:
Lets discuss each of them individually.
Armed with 500mg pure hemp extract and infused with arnica flower extract, this cream does pack a punch. It works on all kinds of aches, pains, and swelling. Black pepper oil warms the skin while aloe vera and coconut oil protect it. The broad-spectrum hemp oil will heal your wounds and reduce inflammation.
Broad-spectrum
Organic aloe leaf juice, organic coconut oil, emulsifying wax, organic arnica flower extract, black pepper oil, organic alcohol, proprietary essential oil blend, organic hemp extract
Natural, with a mild aroma of essential oils
500mg hemp extract
The cream has got close to five-star ratings from 90 reviews. The lowest it has got is three stars from two persons apart from four stars from three persons. Its a full five stars from the rest.
People seemed to have found relief from knee and back pain, arthritic pain, muscle pain, and even frozen shoulder after using this product. Those who gave lower ratings felt they needed a stronger product for their pain.
One customer, however, complained of delivery issues like delays and spotty customer service.
Two of our teammates tried the Pain Relief Cream one for post-workout muscle aches and another for lower back pain.
Both claimed they got some relief from their conditions. The cream has a subtle and pleasant fragrance and is easy to apply.
This is just a stronger variant of the pain relief cream. While the normal pain relief cream has a strength of 500mg, this one has 1000mg. The airless pump also makes it easier to apply.
Broad-spectrum
Organic aloe leaf juice, organic coconut oil, emulsifying wax, organic arnica flower extract, black pepper oil, organic alcohol, proprietary essential oil blend, organic hemp extract
Natural, with mild aroma of essential oils
1000mg hemp extract
The cream has only eight ratings but they are ALL five stars. One customer wrote the cream keeps pain at bay for four hours and thats great for a topical.
Another reviewer said he uses the cream every night and highly recommends it.
This cream is obviously stronger than the 500mg one. The teammate who tested this cream has been suffering from juvenile arthritic pain for ages. He was all praises for the cream and said it gave him relief during a particularly bad bout of pain. You can try it for yourself and see how well it works.
Menthol gives you a cooling sensation while the 1000mg CBD starts working on your pain. At the same time, the goodness of aloe vera nourishes your skin.
How many products can boast such properties?
It dries easily and is easy to apply. Its perfect for sportspersons and fitness freaks. It can give your post-workout body that perfect relief from those cramps and niggling aches.
Broad-spectrum
Menthol USP 3.5%, deionized filtered water, organic aloe extract, isopropyl alcohol, yerba mate leaf extract, camphor oil, Vitamin E acetate, carbomer, FD&C Blue #1 and Yellow #5, triethanolamine, broad-spectrum CBD
Slightly minty, mostly natural hempy
1000mg CBD
The roll-on gel has got 21 reviews. Apart from one, who has rated it three stars, the rest have showered it with five-star ratings. Several users have written that it works on chronic pain, which is hard to get rid of. A woman has mentioned that the roll-on is helping her daughter who has scoliosis, a spinal condition.
Our adventure traveler buddies loved this roll-on gel. One of them went camping over the weekend and we handed him the gel for review. He came back waxing eloquent about the effectiveness of the gel. He suffered a mild sprain and the gel worked wonders to keep him going without too much trouble.
Every company has its share of pros and cons. As a customer, you need to check how these two lists fare against each other and which way the balance tips. Lets check out Well Cares performance.
If youre considering buying hemp topicals, follow this buyers guide before placing your order.
Step 1. What is your requirement? Do you want to use the product to control occasional pain or chronic pain? What kind of pain is it? Is it very severe? Your choice of product should depend on your answers to these questions. If your pain is very severe, its better to go for a strong product. If your pain is mild, you should choose a product of low strength. Its best to start with a product of lower strength, for that matter. You can use a stronger product if it doesnt work.
Step 2. Choose a product thats convenient for you. For instance, if you love to travel, choose one thats easy to apply, such as roll-ons and sprays.
Step 3. Choose a reliable and reputable brand. Such brands may charge a bit higher than the lesser-known ones, but at least you can rest assured that the product would be worth the price.
Step 4. Before you buy any cannabinoid product for pain relief, do consult your doctor, especially if you suffer from certain health conditions and take prescribed medications for those.
A. They do. They have numerous skincare products, such as intense skin relief salve for sensitive skin issues, advanced daily repair body lotion for regular moisturization, a body butter, and several other pain relief variants in topicals.
A. They certainly do. Well Care sells full-spectrum and CBD isolate soft gel capsules of varying strengths, as well as broad-spectrum hemp extract oils of different potencies and flavors.
A: Well Care Botanicals sells broad-spectrum tinctures and chews for all pets. While the tinctures are unflavored, the chews come in beef flavor. The tinctures are mostly meant for calming their nerves, while the chews are great for stronger joints and muscles.
A: Hemp seed oil is not the same as what Well Care sells as Hemp Extract Oil. The former is extracted from hemp seeds by the cold-pressing method. However, hemp extract oil comes from the entire plant and is extracted by the CO2 method. Hemp seed oil doesnt contain any cannabinoids, whereas these hemp extract oils contain cannabinoids.
Hemp-based topicals can be a boon for those who suffer from chronic or frequent pain. Many people often suffer from joint and/or muscle pain, arthritic pain, body pain or ache, or pain born of some other medical condition.
If you are one of them, Well Cares hemp topical products could effectively relieve you of such pain, quickly and without any side effects that often accompany painkillers.
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Well Care Botanicals CBD Topicals: Our Review - Ministry of Hemp
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Army of the Dead mashes a heist flick with zombies – New Times SLO
Posted: at 8:00 am
Writer-director Zack Snyder (Watchmen, Man of Steel, Justice League) helms this mash-up about a team of mercenaries that infiltrates Las Vegas in a bid to steal $200 million from a safe under a casino. The only hitch? Vegas is filled with zombies. (148 min.)
Glen If you're a fan of Zack Snyder's brand of excessive filmmaking, you'll no doubt enjoy this violent, gory romp. On the other hand, if you're annoyed by filmmaking that seems to want to throw everything but the kitchen sink into a film, you're going to despise this over-the-top, trashy pile of nonsense. Even if you're in the second category, you still may want to watch this for Tig Notaro, who's absolutely hilarious as Marianne Peters, a deadpan helicopter pilot. Dave Bautista stars as Scott Ward, who's hired by the mysterious businessman Bly Tanaka (Hiroyuki Sanada), whose $200 million is sitting in a safe ripe for the taking. Ward rounds up a crew that includes experienced zombie killers, and to up the emotional ante, Ward's estranged daughter, Kate (Ella Purnell), comes along for the ride. German safecracker Dieter (Matthias Schweighfer) is also hired, which seems dumb since you'd assume Tanaka would know the combination to his own safe and just hand it over to the team, but Dieter makes for great comic relief. To top it off, things aren't quite as they seem. Tanaka's head of security, Martin (Garret Dillahunt), also comes along to supervise the operation, though there's definitely something shady about him. At nearly 2 1/2 hours, Snyder takes his time introducing us to the various characters, so despite the long list, it isn't confusing, but it is pretty glib and sort of dumb. The film picks up speed when the team is eventually guided into the quarantine zone by The Coyote, Lilly (Nora Arnezeder). Turns out not all zombies are created equal, and Vegas is run by Zeus (Richard Cetrone), who's making more smart zombies like himself. It's one thing to take out "shamblers" the slow mindless undeadit's another to go up against Zeus and his army of fast-moving flesh eaters. Cue exploding blood bags.
Anna You definitely can't analyze the storyline too intricately without seeing some major flaws right away. That said, this was a pretty fun, pretty gross romp through a zombie world, and the ensemble is a good mix of funny folks and badasses. My faves are definitely Notaro's deadpan Peters and Schweighfer's Dieteran inexperienced zombie slayer who isn't prepared for the sheer amount of gore in store for him. The storyline between Scott and Kate, and the rebuilding of their father-daughter relationship is pretty unoriginal, but it helps move things along and gives the characters something to do with any downtime. It definitely made me laugh a few times and made me say "yuck!" a few times more as guts went flying all over the place. I wasn't a fan of the zombies at firstthey don't fit the normal zombie moldbut once we realized they're working to build their own army of the smarter, faster undead, I got into it. It's a long run, but I had fun watching it and I didn't get bored, so kudos to Snyder for that!
Glen He's certainly returned to his roots with this film. Snyder's feature film debut was the 2004 remake of George A. Romero's 1978 zombie classic Dawn of the Dead. Snyder followed with 300 (2006), about Sparta's epic battle against the Persians in 480 B.C. He's a slick filmmaker with a knack for depicting stylized violence. His 2011 fantasy Sucker Punch, about an institutionalized and abused girl who retreats into an alternative reality, is one of his best and most underrated films. By the time he was plucked to direct Man of Steel, Batman v Superman: Dawn of Justice, and finally Justice League, he was Hollywood royalty. In a break from all these big violent films, he's next directing an adaptation of Ayn Rand's novel Fountainhead, about a young architect battling for artistic freedom. Seems like a weird choice, and I hope he has the good sense to skewer Rand's sophomoric brand of libertarianism. Snyder really is an indulgent filmmaker, and Army of the Dead is nowhere near his best, but it's a fun diversion if you can stomach the gore. It also gives Bautista an opportunity to stretch his acting muscles. In his scenes with his movie daughter, you almost forget he's a 6-foot-4 former pro wrestler. There are also better zombie films out there, but for fans of the genre, watching this is a no-brainer ... pun sadly intended.
Anna Bautista was a fun choice, and seeing Las Vegas in tatters is pretty fun, too. Superhero flicks aren't always my thing, so I've missed some of Snyder's work there, but I love a good zombie movie that doesn't take itself too seriously, and Army of the Dead certainly fits that bill. It's gross and gory and totally over the top, the characters all have their own brand of snark, and there's enough comic relief to stay light. It's fun enough to ignore the flaws in the storyline and ride along as this group gets pulled apart. Some get eaten, some sacrifice themselves, some make it out unscathed. There's a nuke headed toward the city to try to wipe out the zombie colony, so of course the team is up against the wire, and time is not on their side. It keeps things rolling, and the film never gets boring. Like you said, fans of the genre will probably have fun with this one, and if zombies aren't your thing, I doubt this is on your watch list anyway.
Senior Staff Writer Glen Starkey and freelancer Anna Starkey write Split Screen. Glen compiles streaming listings. Comment at gstarkey@newtimesslo.com.
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Nepal Is the Boat of Democracy on The Road Ahead – IDN InDepthNews | Analysis That Matters
Posted: at 8:00 am
Viewpoint by Manish Uprety F.R.A.S. and Jainendra Karn
Manish Uprety F.R.A.S. is an ex-diplomat & ALCAPs Special Advisor for Asia & Africa and Jainendra Karn is a senior leader of the Bharatiya Janata Party (BJP). Any views or opinions expressed are solely those of the authors and do not necessarily represent those of IDN-InDepth News.
KATHMANDU (IDN) What a sombre way to start ones day by going through the newspapers and realize the dystopian times we live in. Its just like listening to Paint It Black by the Rolling Stones or pondering about what Ayn Rand had said: There is no difference between Communism and Socialism, except in the means of achieving the same ultimate end: Communism proposes to enslave men by force, Socialismby vote. It is merely the difference between murder and suicide.
April was indeed the cruellest month but so is May, it seems. Germany opposing waiving off COVID-19 Vaccine IPR, Hamas firing one rocket after another into Israel and anti-Semitic crimes flaring up in the US, the US coming to a halt after cyber attack forced the shutdown of fuel pipelines, and the chaos in South Asia.
Second COVID wave in India that jolted the country, China blatantly interfering in the foreign policy of Bangladesh where the nations Foreign Minister AK Abdul Momen had to remind China that being an independent nation Bangladesh shall follow its own diplomatic policy.
And Nepal plunging into fresh turmoil after the President of Nepal dissolved the countrys Parliament, and announced the mid-term polls for November.
It was after the Prime Minister KP Sharma Oli lost the vote of confidence in the Nepalese parliament but was back in power as per Article 78(3) of the Constitution of Nepal.
Of the 232 members present, Oli got only 93, and 124 MPs voted against him. Out of 121 of his own UML partys members, 28 from the dissident faction were not present, and 15 MPs voted not to vote. The anti-Oli faction did not join the floor test by floor crossing but decided to keep away.
The opposition parties, riddled by factionalism, failed to secure majority seats to form a new government and Sher Bahadur Deuba, chief of the main opposition Nepali Congress and other allies, informed that he would not be able to put together a coalition that has majority in the House.
Nepals tryst with democracy is interesting. In the aftermath of the dramatic Royal Family Massacre in 2001, the monarchy was abolished on 28 May 2008 by the First Constituent Assembly in Nepal. But democracy is still an evolving process in the country and fraught with its own set of challenges both internal and external.
Nepal lies between two leading economies of the worldIndia and China. While India is a Socialist state, China is ruled by the Communist State, and it does have a bearing on the local politics of Nepal.
It can be a bit confounding to an outsider and particularly to someone who is from the West. For example, US economist and social theorist Thomas Sowell had noted that whole political vision of the left, including socialism and communism, has failed by virtually every empirical test, in countries all around the world. But this has only led leftist intellectuals to evade and denigrate empirical evidence.
Interestingly China is now the Trade Titan of the world whose economy is almost five times larger than that of Indias. Also as per the 2021 Military Direct's study, China has the world's strongest military where as India stands at the fourth place.
But there is a notion in the Chinese strategic circle that though India always had a strong influence over many South Asian countries' decision-making on foreign policy, India's hegemony in South Asia is not that firm. Hu Zhiyong, a research fellow at the Institute of International Relations of the Shanghai Academy of Social Sciences mentions the same.
Indeed, the argument by Hu Zhiyong holds a great merit because the disparity between India and China has resulted in the latters significant interference in the South Asian region that has affected the state of local equilibrium.
With the China-Pakistan Economic Corridor (CPEC) losing its steam in Pakistan, Chinas intrusion in the Ladakh region of India last year and in May 2021 the reports of Chinese Villages and Security Forces revealed inside Bhutan's borders are incidents that make one very circumspect of the Chinese strategic design for the region.
In June 2020, it was reported that China had occupied Rui village of Nepal and annexed it to Tibet. Jeevan Bahadur Shahi, former Tourism Minister of Nepal had said that Chinese troops had crossed the border and built nine concrete structures about 1 km inside Nepal, at Limi in the district of Humla bordering Tibet.
During his recent visit to Dhaka, the Chinese Defence Minister Wei Fenghe had warned Prime Minister Sheikh Hasina's government that China does not want any form of participation of Bangladesh in QUAD alliance as Beijing sees it as an anti-China grouping.
On 21 May 2021, China's State Council Information Office brought out a white paper titled Tibet Since 1951: Liberation, Development and Prosperity' which is interpreted as a means to blunt India and the Wests diplomatic advantage.
Democratic processes especially elections across the world are like a bird on a wire which is a temptation for any bird of prey. Chinas embrace of the Black Lives Matter (BLM) movement in the US during the 2020 Presidential elections can be seen as an example of this.
However, in the case of evolving democracies where violence and power still hold sway, time tried tactics of gunboat diplomacy can still work. On 8 May 2021, the U.S. 5th Fleet seized weapons shipment from a stateless dhow in the North Arabian Sea which was mainly of the Chinese origin.
The pertinent question is who wanted these weapons that were confiscated between Pakistan and West Asia? Arms and ammunition just like money and drugs, can be transferred illegally anywhere in the world to cause unrest and also to compromise democracy.
However, the forthcoming elections scheduled for November 2021 in Nepal not only outside factors along with local issues will matter but also COVID-19. One has witnessed how great an impact COVID-19 can have in the recent state elections in India such as in West Bengal.
This will be a very tricky affair. India recently had some glitches in its vaccine production capacity which the country is trying to fix so that a country of over a billion people can be inoculated while meeting its international commitments. Not to mention India made vaccines are amongst the cheaper and most effective ones in the world that have a special relevance for developing countries.
There are very serious doubts about the efficacy of the Chinese vaccines in the international community. Seychelles, worlds most vaccinated country, where majority of vaccinated received Chinas Sinopharm vaccine, recently reported an unprecedented Covid-19 surge among fully inoculated individuals. UAE and Bahrain have also questioned the efficacy of Sinopharm vaccine.
How policymakers in Nepal will meet this challenge posed by COVID-19 before the elections are held needs to be seen. With only six months to go, one way could be that the government of Nepal directly talks to its Indian counterpart so that the vaccines can be secured without the involvement of middlemen or explore the international market where it might have to pay more.
Between Nepal and India, the situation is very unique as both the countries share economic and military ties besides the people-to-people, cultural, historical, and religious ties. Even the Communists are bound by Nepals religious traditions, says Nepalese scholar Dr. Ramesh Dhungel, so the latter assumes significant importance. Trying to ride the fine line of balancing these concerns is the key.
There is no doubt that no country can close its eyes to Chinas participation in its economic development because of its sheer economic prowess and might. But in the context of Nepal, the issue of Indias security concerns and problems of over dependence on China also raise their head.
The forthcoming elections will give an opportunity to the peoples of Nepal to move beyond the clichd connotation of buffer between India and China that has been associated with it for a very long time.
Nepal has the potential to be the Switzerland of Asia. It must harness and make the best of the opportunities that it is receiving from its neighbours while treading prudently on the path of development to deliver fruits of progress to its peoples. [IDN-InDepthNews 26 May 2021]
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Photo: (From Left to Right) Manish Uprety F.R.A.S. Mr. Bimalendra Nidhi, Ex-Deputy Prime Minister of Nepal and Jainendra Karn.
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Video Games That Are Based on Novels Film Daily – Film Daily
Posted: at 8:00 am
You might have heard of many great movies being adapted into games and vice versa. However, adapting novels into video games makes for quite an exciting experience. Through the video game format, you get to experience the authors imaginative world in great detail. Here are some video games that are based on novels:
The Witcher trilogy of games by CD Projekt is one of the most popular games out there. This fantasy action role-playing game is based on a book series by the same name written by a Polish writer called Andrzej Sapkowski. The Witcher is also now a successful TV series on Netflix.
You play the fun character called Geralt of Rivia. You will have to use your supernatural abilities and hunt down and kill all the beasts. Witcher 3 has been praised for its beautiful environment, and it is fascinating to walk through the woods and towns in the game.
Assassins Creed has to be one of the most successful video games. It is absolutely adored by the gamer community. But did you know that the inspiration for the first Assassins Creed game actually came from a 1983 novel called Alamut written by Vladimir Barton?
Alamut is about a man called Hassan-Ibn-Sabbah who basically finds an order of elite fighters or assassins to attack the Seljuk Empire. The book explores how the assassins are devoted to Sabbahs cause in order to reach heaven. The maxim in the book, Nothing is an absolute reality, all is permitted was changed to Nothing is true, everything is permitted in the game.
Specs Ops is one of the most unique and unconventional third-person shooter games with an incredible storyline. The game starts with a group of soldiers who are tracking down the survivors of the Dubai sandstorm. It has lots of firefights and interesting maps.
This game is actually a direct adaptation of an 1899 novella called Heart of Darkness which is written by a Polish-English novelist named Joseph Conrad. The book explored the issues of imperialism and colonialism in great detail.
BioShock is regarded as one of the most influential games ever made. It was praised for its storyline, which explored the concept of morality in great detail. The gameplay and environment are incredibly immersive and dystopian.
The storyline is hugely influenced by the book written by Ayn Rand called Atlas Shrugged. In fact, the game actually exists as a criticism of the philosophy of Objectivism in Rands book. It explores all the power dynamics in people and how self-interest is valued more than anything else.
Bloodborne is one of the most incredible horror games that you will ever play. If you havent played it yet, make sure to add it to your list. The game is inspired by the author H.P. Lovecraft as you can see elements like cosmic horror and the fear of the unknown being explored in the game.
Bloodborne is not your average horror game. Its atmosphere is rich and unparalleled as it embraces many Lovecraftian elements. The game is fast-paced and incredibly challenging as you have to fight your way through dangerous and terrifying creatures in a grim atmosphere.
This real-time strategy game which is developed and published by the famous Electronic Arts, is based on the hugely influential epic high fantasy novel Lord of the Rings written by the father of modern fantasy, J.R.R. Tolkien.
If you are someone who loved the Lord of the Rings movies, you get to relive the battle scenes and locations as you fight the Goblins, Orcs and Ringwraiths in campaign mode. If you are someone who loves to play on slot online terpercaya and other online casino websites, you will be happy to know that there are Lord of the Rings themed slot machine games that you can play in many casinos!
This game managed to turn the popular childrens books Alices Adventures in Wonderland and Through the Looking Glass written by Lewis Carroll into a dark and interesting game. It is a beautiful game filled with many artworks. There is a great spin on Alices character where she is no longer the innocent Alice that you know.
If you are someone who loves horror, you should absolutely try this brilliant psychological horror game. This fun shooter game will keep you occupied for hours. The soundtrack is scary and gorgeous as well. You are sure to have a lot of fun with the wittiness and charm of the game.
If you want to have a new appreciation for these video games, you can try getting your hands on these novels and giving them a read. It will surely give you a deeper insight into the game and an interesting gaming experience as well.
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Vanguard – Fixed income – GNMA
Posted: at 8:00 am
The Government National Mortgage Association (GNMA or Ginnie Mae) issues agency bonds backed by the full faith and credit of the U.S. government. GNMA guarantees principal and interest on mortgage-backed securities (MBS) backed by loans insured by the Federal Housing Administration and the Department of Veterans Affairs. New GNMAs are issued in $25,000 minimum denominations.
MBS are an investment in a pool of mortgage loans, which are the underlying asset and provide cash flow for the securities. MBS are commonly referred to as "pass-through" securities, as the principal and interest of the underlying mortgage loans "passes through" to the investor. All bondholders receive a monthly pro-rata distribution of principal and interest over the life of the security. MBS are issued with maturities of up to 30 years, though most mature earlier.
Each MBS has an average life, an estimate of the time remaining until the final principal payment. Average life will vary based on changes in principal payments, which are driven by interest rates and the speed by which mortgage holders prepay their loans.
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