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Daily Archives: February 21, 2021
Windshields smashed, nerves shattered as cars, trucks fling icy snow on highways – WLWT Cincinnati
Posted: February 21, 2021 at 12:27 am
With all the snow we've gotten, there's no doubt you've probably seen cars and trucks flinging ice and snow on the highway.More and more people have said their cars are taking the brunt of the damage.Drivers said it's time for people to do the right thing and clean their cars as we prepare for more snow."Just this morning, I was driving on the highway and a few cars in front of me, just some ice flew off," driver Chris Rolfsen said.It's Russian roulette on the road."You think I warmed it up. I'm good. I defrosted everything. No. You need to clear all the ice off your car," driver Dariyel Maull said.Drivers are getting slammed with ice and snow from nearby cars and trucks smashing their windshields and shattering their nerves.WLWT obtained video from the Norwood Lateral showing the ice fly off a semi-truck.Then, there's more on I-75.Dylan Moermond, 20, got iced on Wednesday."It was really scary. It's kind of sad, too, because today's my birthday, so, pretty bad birthday present," Moermond said.He's had his car just three months."It hit and when it hit, it dented this in right here, took off the paint right there and then, come over here, you can see the mirror right here got all cracked in and everything," he said.Drivers admit that digging out is tough in the cold.But in Ohio, police said it's illegal to not clear snow and ice from your windows, headlights and taillights, and license plate.They said there is no rule against driving with snow on the roof, hood or trunk.Kentucky State Police said people can be cited for having an obstructed view.Meanwhile, the ice and snow keep flying off the car nearest you.We obtained more video showing ice fly off a car near Dana Avenue.That ice hit the ground.With more snow coming, drivers said enough is enough, and that everyone should take the extra time to do what's right."It's definitely dangerous, you know, you're moving at 65 miles an hour. A piece of ice could go through your windshield or something like that," Rolfsen said.Moermond said his insurance will cover the damage, and despite the bad birthday present, he's just glad he wasn't hurt and there wasn't a wreck.Police said you need to make sure your car is safe for everyone on the road.If you knowingly drive a car that endangers others, you could be charged with a misdemeanor.
With all the snow we've gotten, there's no doubt you've probably seen cars and trucks flinging ice and snow on the highway.
More and more people have said their cars are taking the brunt of the damage.
Drivers said it's time for people to do the right thing and clean their cars as we prepare for more snow.
"Just this morning, I was driving on the highway and a few cars in front of me, just some ice flew off," driver Chris Rolfsen said.
It's Russian roulette on the road.
"You think I warmed it up. I'm good. I defrosted everything. No. You need to clear all the ice off your car," driver Dariyel Maull said.
Drivers are getting slammed with ice and snow from nearby cars and trucks smashing their windshields and shattering their nerves.
WLWT obtained video from the Norwood Lateral showing the ice fly off a semi-truck.
Then, there's more on I-75.
Dylan Moermond, 20, got iced on Wednesday.
"It was really scary. It's kind of sad, too, because today's my birthday, so, pretty bad birthday present," Moermond said.
He's had his car just three months.
"It hit and when it hit, it dented this in right here, took off the paint right there and then, come over here, you can see the mirror right here got all cracked in and everything," he said.
Drivers admit that digging out is tough in the cold.
But in Ohio, police said it's illegal to not clear snow and ice from your windows, headlights and taillights, and license plate.
They said there is no rule against driving with snow on the roof, hood or trunk.
Kentucky State Police said people can be cited for having an obstructed view.
Meanwhile, the ice and snow keep flying off the car nearest you.
We obtained more video showing ice fly off a car near Dana Avenue.
That ice hit the ground.
With more snow coming, drivers said enough is enough, and that everyone should take the extra time to do what's right.
"It's definitely dangerous, you know, you're moving at 65 miles an hour. A piece of ice could go through your windshield or something like that," Rolfsen said.
Moermond said his insurance will cover the damage, and despite the bad birthday present, he's just glad he wasn't hurt and there wasn't a wreck.
Police said you need to make sure your car is safe for everyone on the road.
If you knowingly drive a car that endangers others, you could be charged with a misdemeanor.
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Windshields smashed, nerves shattered as cars, trucks fling icy snow on highways - WLWT Cincinnati
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Josh Freed: COVID has robbed us of small talk, and that’s a big deal – Montreal Gazette
Posted: at 12:26 am
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We have less and less to say to each other thats new, exciting or interesting. Thats because no ones been anywhere exciting, done anything exciting or even met anyone new and exciting.
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The other day I had a very exciting COVID experience.
I passed a school crossing guard and said: Bonjour, a va? and he looked straight at me from behind his mask and replied:
Oui, Monsieur! Mais cest trs froid, non?
Oui, cest froid! I nodded, ending one of my most talkative and thrilling encounters with a stranger in months.
Almost a year into COVID, theres much talk of the obvious things we miss: seeing our parents, kids and close friends in person; going to restaurants, bars, theatres, concerts and festivals.
Travelling! Even a drive to Ottawa sounds like an exotic expedition nowadays.
But what doesnt get mentioned much might be most important of all: having occasional chats with acquaintances, neighbours and utter strangers that add novelty and variety to life.
Most of us are keeping up with family and close friends, on walks or talks online. But we have less and less to say to each other thats new, exciting or interesting.
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Thats because no ones been anywhere exciting, done anything exciting or even met anyone new and exciting.
Were all treading water. At COVIDs start, which seems like a decade ago, at least it had a certain horror-film excitement that had us chattering away:
Person 1: Omigod! Do you think I should open this envelope from Columbia University, or quarantine it for three days? It could be my daughters acceptance letter but its from New York, which is a plague zone!
Person 2: No way Id touch that! Just put on rubber gloves and burn it in the sink before it contaminates your whole house.
But now, almost a year later, were largely numb to COVID and theres not much to yak about, apart from:
Didja hear were down to 800 new cases today? Pretty good, eh?
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Yeah, pretty good. I hear Ontario had 900.
Yep (long silence)
So, seen anything good on TV lately?
Frankly, I havent had a memorable conversation in months.
Behind this problem is the massive shrinking of our social worlds. Perhaps youre talking to five or 10 people, even Zooming with 25.
But studies show the average person actually knows around 350 people (not counting online friends) from their butcher and baker to many acquaintances they see occasionally.
And we just arent seeing them anymore.
For instance, I miss the gang of 10 tennis buddies I used to see every Wednesday, then share a drink-and-yak with. Weve met online occasionally, but theres no zing in Zoom.
I miss dropping by my local caf and exchanging greetings with neighbourhood characters I kind of know and waiters who kind of know me.
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I miss my decades-old annual Super Bowl party at a pals house, where Id see several football fans I never saw elsewhere but I loved meeting up with them.
I miss the many now-and-thenners in my life who gave it spice.
Like everyone, I also miss dinners and parties where you sometimes talked to actual strangers whod share their life story, or details of their fascinating job as a rodent catcher, or soldier or poet.
I miss yakking with shopkeepers now walled off by Plexiglas and as eager as me to keep COVID conversations brief. Try talking to a stranger in your supermarket queue and theyll leap back like you were a germ warfare weapon which maybe you are.
I miss cabbies and Uber drivers who I rarely use anymore. If I do, I open a window that drowns out any conversation who wants to share the air?
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I miss cosy nostalgic chats across tiny restaurant tables, catching up with long unseen friends over a bottle of wine. I miss personal gossip, which has practically evaporated, along with peoples personal lives.
Like those new contact-free payment methods we use for stores and deliveries, we have less and less contact. Period.
Its hardest on single people who often eat alone every night, their only company the evening news.
Whats lost in this is more than the simple sum of all these small chats. When we dont talk to new people with new stories, ideas and life experiences, we have less to bring with us to the next conversation, or Zoom.
Its the same for those were talking to, as our worlds shrink and we lose our sense of a larger community.
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Recently I find my conversations getting shorter and shorter, even with good friends, as we run out of fresh chit-chat. If this pandemic goes on much longer, will the whole city, country and world go on mute?
Will conversation just die, another casualty of COVID?
For all our obsession with diet and fitness, longevity studies show that our social lives may be most important of all. People who thrive with age are often connected and interacting with many people.
So along with your daily yoga, jogging, Zumba and Peloton exercises, do some lip stretches, tongue twists and voice exercises, too.
When this pandemic finally ends, well all have a lot of catching up to do.
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Josh Freed: COVID has robbed us of small talk, and that's a big deal - Montreal Gazette
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Tiffany Haddish Uses This $9 Soap to Treat Her Eczema – NewBeauty Magazine
Posted: at 12:25 am
According to Allergy & Asthma Network, 7.3 percent of adults in the United States have atopic dermatitis, and actress Tiffany Haddish just revealed that she is part of that number in this weeks issue of People. If youre in the same boat, the star offered up some insight on the product she uses to soothe her irritated skin. And to our surprise, its extremely affordable.
So beauty-wise I wash my face with the same thing I wash my body with, which is this pure spearmint gum, turpentine soap mixed with olive oil that I found on Amazon, she tells People. It gets rid of eczema, dry spots, rashes and stuff like that. According to Haddish, the product, which she later pins as Diamond G Forest Products Turpentine Soap ($8), is so good, I had told one of my co-stars [about it] because she was saying her baby had eczema. I said, Try this soap. So I gave it to her. She was like, Tiffany its good, the eczemas gone!'
The Like a Boss stars other favorite skin-care product includes another all-natural must-have that is known for its skin-silkening properties: coconut oil. I soak my face in that, wash it off and then Ill use castor oil on my eyelids to help make my eyelashes grow, she says. When shes craving a more luxurious makeup-melter, shell reach for the Tatcha Camellia Oil ($48), which leaves the skin softer than ever come morning.
Like her beauty routine, Haddishs hair-care lineup is so low maintenance, she recently decided to shave her head, which, according to People, she says shes always wanted to do. Just loving my new look thought Id share it with yall, she recently captioned an Instagram post. The best part is when water hits my head it feels like kisses from God.
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Tiffany Haddish Uses This $9 Soap to Treat Her Eczema - NewBeauty Magazine
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Atopic dermatitis in children: when topical steroid treatment does not work – The BMJ
Posted: at 12:25 am
If topical corticosteroids for atopic dermatitis do not seem to work, explore how they are being used (quantity, frequency, duration of application), the appropriateness of steroid potency prescribed, the ongoing use of moisturisers, the presence of other skin infections, and potential allergen exposure
Many other conditions mimic atopic dermatitis in children, so the diagnosis warrants frequent review to assess for treatment response, especially if the skin lesions look atypical
Refer patients who do not show clinical improvement or who experience frequent, severe flares while on confirmed, adequate topical therapyor patients for whom the diagnosis is unclearto a paediatric dermatologist or paediatrician to consider the use of second line therapy or to explore alternative diagnoses
A 1 year old boy visits your clinic. He received a diagnosis of atopic dermatitis six months ago. On return visit today, his rash and pruritus have worsened despite intermittent application of a small quantity of hydrocortisone 1% cream. His sleep has been constantly interrupted by scratching. On examination, his skin is dry with excoriated, erythematous plaques on his limbs and trunk. His parents want to stop using topical corticosteroids (TCS) out of concern for side effects and because the cream is not working.
Atopic dermatitis, a type of eczema, is the most commonly diagnosed paediatric dermatosis (box 1), affecting about 20% of children.2
Pruritus
Acute: Erythematous papules, scaly patches with oedema and excoriations that are distributed in age related patterns (eg, face, trunk, and extensor surfaces of extremities in infants, flexural surfaces in children)
Chronic: Lichenification, dyspigmentation
Emollients are essential treatment for acute flare and for maintenance, and TCS continue to be the first-line drug treatment.23 Sub-optimal management results in poor control of symptoms, which negatively affects quality
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Atopic dermatitis in children: when topical steroid treatment does not work - The BMJ
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Skin expert gives mommy advice on caring for children with eczema – Philstar.com
Posted: at 12:25 am
MANILA, Philippines Atopic dermatitis, more commonly known as eczema, is one of the most common inflammatory skin conditions affecting people of all ages, especially children, throughout the world.
According to a 2017 article published by the American Journal of Managed Care, the incidence rate of the disease has reportedly doubled or tripled in industrialized countries since the 1970s. Of this, 15% to 20% are children.
In the Philippines, records from Philippine Dermatological Society-accredited institutions show that 65.1% of outpatients with eczema are children aged 1 to 12 years, and 24% are infants who are less than 1 year old.
Young as they are, children cannot fully understand the effects of eczema, especially if untreated, on the quality of their lives. It is therefore imperative for moms to take immediate steps to address this skin concern.
It begins by knowing what exactly eczema is, from its causes to diagnosis, even myths surrounding it, and finally proper treatment, especially now in the face of a health crisis.
Dr. Ma. Victoria Dizon, pediatric dermatologist, lends her expertise to help moms better care for their kids with eczema.
Eczema is characterized by a rash that is itchy and red.
According to Dr. Dizon, eczema is characterized by a rash that is itchy and red, which are mostly identified as contact or seborrheic dermatitis, among others.
In worse cases, it can develop tiny blisters that lead to an oozing weeping wound, she shares.
She adds to watch out for visible signs including:
Environment triggers like heat, sweat, dust and pollution, can challenge the sensitive skin and cause the eczema.
While genetics play a big part in developing eczema, there are other important factors that cause it.
Environment triggers like heat, sweat, dust and pollution, can challenge the sensitive skin and cause eczema. The causes of eczema in children may differ from the adults because kids may have different allergen exposures based on their activities, like outdoor sports for example, while adults have occupation-related causes, Dr. Dizon explains.
Given genetic propensity and environmental factors that lead to eczema, this sheds light on the misconception that it is contagious. Eczema simply isnt.
One way to mitigate or prevent the occurrence of eczema flares is to use mild, moisturizing soaps or cleaners as hand soaps.
Significant shifts in everyday life have been observed as a result of the global health crisis, including constant handwashing and frequent use of alcohols and other disinfectants.
These have become major triggers for eczema breakouts, as the said products strip away the skins natural oils and interrupt the skin barrier by increasing its pH levels, directly resulting in alkalinity.
One way to mitigate or prevent the occurrence of eczema flares is to use mild, moisturizing soaps or cleaners as hand soaps.
It is equally important to restrict the use of alcohols and other disinfectants and to reserve them only when soap and water are not readily available.
Frequent moisturizing of the skin will also function as a preventive and repairing step to address eczema problem, adds Dr. Dizon.
When caring for children with eczema, moms must always remember that they are dealing with sensitive skin.
As the primary caregivers of children with eczema, moms must always remember one thing: They are dealing with children who have sensitive skin.
With this, Dr. Dizon shares tips to makes sure that their childs skin is able to repair itself and stay healthy:
Lastly, moms must also be more discerning with the types of products they use to treat eczema.
When it comes to topical medications, moms need to be more scrutinizing.
When it comes to topical medications, Dr. Dizon advises moms to be more scrutinizing.
They should look for medicines that are mild or not too strong for use on childrens skin. They should also consider the choice of topical medication that is recommended by the doctora pediatrician, a family practice doctor, or a dermatologist/pediatric dermatologist), she says.
Avoid topical medications that can irritate that delicate skin. Never use topical medications that are too strong for the skin and those that can cause an allergic reaction, she continues.
When it comes to eczema relief, moms can trust Bepanthen.
When it comes to healing and regeneration of vulnerable skin during and following eczema flare-ups, moms can choose Bepanthen products.
A steroid-free spot treatment, Bepanthen Itch Relief Cream contains dexpanthenol, a highly absorbent fatty emulsion that relieves eczema itch in as much as 30 minutes while repairing damaged skin barrier.
On the other hand, Bepanthen Sensidaily is formulated with prebiotics that support the skin's natural microflora, as well as niacinamide that helps regenerate the skin from within.
With these benefits, Bepanthen Sensidaily is clinically tested to help keep the skin flare-free for up to three months with regular use. It also helps keep the skin deeply hydrated which is essential to keeping the skin barrier strong and healthy.
Together, Bepanthen Sensidaily and Bepanthen Itch Relief Cream provide moms an eczema management solution for their children.
For more information, visit the official Facebook account here. Bepanthen is available online via Shopee and Lazada, and in leading drugstores nationwide.
If symptoms persist, consult your doctor.
ASC Reference Code: B068P020221BS
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Skin expert gives mommy advice on caring for children with eczema - Philstar.com
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Kyowa Kirin Announces Positive Phase 2 Results for KHK4083 in Patients with Moderate to Severe Atopic Dermatitis – PRNewswire
Posted: at 12:25 am
TOKYO, Feb. 18, 2021 /PRNewswire/ -- Kyowa Kirin Co., Ltd. (TSE: 4151, President and CEO: Masashi Miyamoto, "Kyowa Kirin"), a global specialty pharmaceutical company that strives to create new value through the pursuit of advances in life sciences and technologies,announces today that the Phase 2 study of investigational agent KHK4083 in patients with atopic dermatitis has met the primary endpoint.
KHK4083 is a potential first-in-class, anti-OX40 fully human monoclonal antibody for the treatment of autoimmune diseases, including atopic dermatitis. KHK4083 was first discovered by Kyowa Kirin, and is produced with the Company's patented POTELLIGENT defucosylation technology to enhance its antibody dependent cellular cytotoxicity(ADCC) activity2. The combination of ADCC and antagonist activity against OX40 may suppress inflammatory responses found to be the cause of atopic dermatitis3-6.
The Phase 2 study was a multicenter, randomized, double-blind and placebo-controlled clinical study conducted in Japan, the United States, Canada, and Germany to investigate the efficacy and safety of KHK4083. Globally, 274 patients with moderate to severe atopic dermatitis, who were not adequately controlled with topical agents, were enrolled in the study.
In this study, all KHK4083 cohorts achieved superiority to placebo cohort for the primary endpoint of "percent change from baseline in Eczema Area and Severity Index (EASI) 7 at 16 weeks" with statistical significance. In addition, there was significant difference in "the percentage of patients achieving an EASI-75 (EASI score of 75% or greater improvement from baseline) at 16 weeks" and "the percentage of patients achieving the Investigator's Global Assessment (IGA) of 0 or 1 with an improvement of 2 points or more at 16 weeks" in all KHK4083 cohorts compared to the placebo cohort. Further improvement in efficacy of KHK4083 was observed after week 16. Common treatment-emergent adverse events for KHK4083 cohorts were pyrexia, nasopharyngitis, worsening of atopic dermatitis and chills during the first 16 weeks. No deaths were observed in the study.
"The results of the KHK4083 Phase 2 study show that OX40 is a relevant target for atopic dermatitis and may provide a new treatment paradigm," said the lead investigator of this study, Dr. Emma Guttman-Yassky, MD./PhD., System Chair for the Department of Dermatology and Waldman Professor of Dermatology and Immunology, Icahn School of Medicine at Mount Sinai and Director of the Center for Excellence in Eczema, and the Laboratory of Inflammatory Skin Diseases at Mount Sinai. "In addition to the primary endpoint, this study also showed progressive improvement in efficacy by continuous KHK4083 administration beyond 16 weeks andthe potential for long-term sustained therapeutic effect after the completion of KHK4083 treatment."
"We are very pleased with the results of this studyshowingefficacy and safety of KHK4083 in chronic, recurrent, moderate to severe atopic dermatitis," said Yoshifumi Torii, Ph.D., Executive Officer, Vice President, Head of Global R&D Division of Kyowa Kirin. "We look forward to sharing the results of the full analysis in the near future. I would like to express my deep gratitude to the medical professionals and patients for their participation in the study. We will continue KHK4083 development with the hope it can help patients in need."
The full results of the study are planned to be presented through future academic conferences and publications.
The Kyowa Kirin Group companies strive to contribute to the health and well-being of people around the world by creating new value through the pursuit of advances in life sciences and technologies.
About Atopic DermatitisAtopic dermatitis is a disease in which the main lesion is an itchy eczema that repeatedly flares up and flares down, and many patients have a predisposition to atopic dermatitis (family and previous history, predisposition to produce IgE antibodies). It is an eczematous disease with a characteristic symmetrical distribution, and the site of predilection differs according to age. Characteristic eczematous lesions that develop in infancy or early childhood, remit in childhood, or recur without remission, and persist into adulthood, are seen chronically.
About OX40OX40 is a co-stimulatory molecule that is one of the tumor necrosis factor receptor (TNFR) family member and plays an important role in maintaining T cell proliferation and survival by inhibiting apoptosis and in the formation of memory T cells. OX40 is also expressed on the surface of effector T cells (CD4 positive) activated by antigens. It has been reported that effector T cells expressing OX40 are present in the lesions of atopic dermatitis3-6.
About Eczema Area and Severity IndexEASIEASI is an internationally used classification of atopic dermatitis severity and is recommended for use by Harmonising Outcome Measures for Eczema, an international group for standardizing clinical trial outcomes in atopic dermatitis7.
About Kyowa KirinKyowa Kirin strives to create and deliver novel medicines with life-changing value. As a Japan-based Global Specialty Pharmaceutical Company witha 70-year heritage, we apply cutting-edge science including an expertise in antibody research and engineering, to address the needs of patients and society across multiple therapeutic areas including Nephrology, Oncology, Immunology/Allergy and Neurology. Across our four regions Japan, Asia Pacific, North America and EMEA/International we focus on our purpose, to make people smile, and are united by our shared values of commitment to life, teamwork/Wa, innovation, and integrity. You can learn more about the business of Kyowa Kirin at: https://www.kyowakirin.com.
References
SOURCE Kyowa Kirin Co., Ltd.
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Kyowa Kirin Announces Positive Phase 2 Results for KHK4083 in Patients with Moderate to Severe Atopic Dermatitis - PRNewswire
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Whats Heartleaf? It’s the Newest & Buzziest K-Beauty Ingredient – PureWow
Posted: at 12:25 am
Innovation in K-Beauty never ceases to amaze us. In addition to developing ingenious regimens and easy hacks, Korean beauty brands have introduced us to some game-changing skincare ingredients including snail mucin, propolis, and bamboo.
The newest buzz-worthy ingredient on top of the K-Beauty 2021 trend forecast? Heartleaf (scientifically known as houttuynia cordata), a flavonoid and flowering plant native to Southeast Asia, according to board-certified plastic surgeon Dr. Michele Koo, MD.
In Southeast Asia, houttuynia cordata is eaten as a leafy vegetable that contains antioxidant, anti-bacterial, and anti-inflammatory properties, Dr. Koo explains. Its potential for skincare is promoted because of its anti-inflammatory (think blemishes, rashes, eczema) and hydrating properties.
But thats only the beginning. So, we tapped Dr. Koo (plus a few other skincare pros) to share all the ins-and-outs of the ingredient, as well as some easy ways to introduce it into your routine.
According to a 2014 study published in Pharmacognosy Review, heartleaf is traditionally used for medicinal purposes in North-East India and China. Raw leaves and extract from the plant are consumed to purify the blood and to relieve inflammatory conditions in the body.
However, its worth noting that heartleaf can also be used topically. A 2010 study published in the Chonnam Medical Journal suggests that the plant can treat snake bites, as well as skin disorders such as acne and atopic dermatitis.
The plant has been shown to have antioxidant and anti-inflammatory properties, says Dr. Kim. However, whether that translates to smoothing rough, angry, and fickle skin (or removing blemishes) is still not known, she notes, citing the need for additional research. In other words, dont think of this as a cure-all ingredient just yet.
Sensitive and dry skin types are best suited for products containing heartleaf because the ingredient is a humectant, meaning it moisturizes, and has soothing, anti-inflammatory properties, explains Dr. Koo.
New York City-based dermatologist Dr. Debra Jaliman, MD, warns that some people with extremely sensitive skin could have adverse reactions when using products that contain heartleaf. Which is why she recommends doing a patch test on your arm first to see how your skin reacts. Some people get tingling from this ingredient, Dr. Jaliman explains. If you have very red skin, rosacea, or bad eczema, you may want to avoid it."
Additionally, board-certified dermatologist Dr. Lavanya Krishnan, MD, advises against using heartleaf products if you have allergies to sulfonamides, which are medicines used to treat bacterial infections.
Because of its soothing and anti-inflammatory properties, heartleaf is often incorporated into skincare products like facial masks, toners, and creams, says Dr. Koo. And thanks to its antibacterial properties, its can be a helpful ingredient in acne products for sensitive skin, adds Dr. Krishnan.
But before adding some heartleaf-infused products to your shopping cart, Dr. Koo advises remembering that the extraction process of the plant can vary by brand, which might impact the quality of the product youre using.
It is extremely important to select products from brands that are very transparent about their production processes, and hold themselves to a higher standard, she says. Sometimes the extraction methodology contains residual toxic ingredients and can actually be harmful. Make sure you trust the product line to deliver clean, pure healthy ingredients.
RELATED: Why Everyone Is Trying the 3-Second Rule of Korean Beauty
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Whats Heartleaf? It's the Newest & Buzziest K-Beauty Ingredient - PureWow
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Mild To Moderate Atopic Dermatitis Treatment Market to Stand Tall from 2020 to 2030 NeighborWebSJ – NeighborWebSJ
Posted: at 12:25 am
Mild-to-moderate atopic dermatitis is a chronic inflammatory skin disease often confined to the flexural surfaces of the body and usually begins in childhood. This skin disease affects a large percentage of the worlds population. Atopic dermatitis is also known as eczema which is characterized by itching, swelling, dry skin, redness, vesicle formation, crusting, cracking, scaling and weeping. Atopic dermatitis is a long-term skin disease, which is classified into different types depending on the skin condition such as contact eczema, allergic contact eczema, neurodermatitis, dyshidrotic eczema, nummular eczema, stasis dermatitis and seborrheic eczema. Multiple factors are responsible for mild-to-moderate atopic dermatitis which include low humidity, cold weather, seasonal allergies, and exposure to harsh soaps and detergents.
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Mild-to-Moderate Atopic Dermatitis Treatment Market: Drivers and Restraints
Large patient population and new product launches are factors projected to drive the growth of mild-to-moderate atopic dermatitis treatment market globally. According to the United Nations Population Fund (UNFPA), the global population is growing at a rate of 1.1%. Climatic changes and large pipeline products are factors which are estimated to fuel the growth of this market. However, stringent regulations for product approvals and generic competition are the factors which hinder the market growth of mild-to-moderate atopic treatment market globally.
Mild-to-Moderate Atopic Dermatitis Treatment Market: Segmentation
By treatment type the mild-to-moderate atopic dermatitis treatment market can be segmented into
By distribution channel the mild-to-moderate atopic dermatitis treatment market can be segmented into
Drug treatment can further be segmented into antihistamines, antibiotics, emollients, corticosteroids, and calcineurin inhibitors. Topical corticosteroids are the standard treatment for most patients with atopic dermatitis for more than 50 to 60 years. Calcineurin inhibitors are used as second line treatment drug for atopic dermatitis. Recently the U.S. Food and Drug Administration has approved Eucrisa a topical treatment for children and adults with mild-to-moderate atopic dermatitis. Eucrisa works differently than other topical treatments on the market.
Mild-to-Moderate Atopic Dermatitis Treatment Market: Overview
The medication treatment of the skin disease depends on the duration, pattern, and severity of the skin lesions. Except drug therapy, atopic dermatitis is treated with ultraviolet light therapy. According to the American Academy of Dermatology (AAD), the atopic dermatitis that emerges in adults is often different and more severe than infants and children. According to Anacor Pharmaceuticals, Inc., atopic dermatitis is estimated to affect about 18% of infants and children in developed countries. These disease often becomes milder with age.
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Mild-to-Moderate Atopic Dermatitis Treatment Market: Region-wise Outlook
Geographically, the market is segmented into North America, Latin America, Europe, Asia Pacific and Middle East and Africa. North America leads the market for mid-to-moderate atopic dermatitis reasons being lifestyle changes, new product innovations, and early treatment adoption. A large proportion of the U.S. population has symptoms of eczema. According to the National Eczema Association in the U.S., approximately 30 million people are living with eczema, and the prevalence rate of childhood eczema is 10.8%. Europe is the second leading market for mild-to-moderate atopic dermatitis treatment due to development activities and large research base. The Asia Pacific market is also expected to grow at a higher rate owing to changing lifestyle, large target patient pool, rapid population growth, adoption of western lifestyle, and growth in research and development. These factor are likely to drive the market growth of mild-to-moderate atopic dermatitis treatment market during the forecast period globally.
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Mild-to-Moderate Atopic Dermatitis Treatment Market: Key Players
The major players in mild-to-moderate atopic dermatitis treatment market include Anacor Pharmaceuticals, Inc., Astellas Pharma Inc., Meda Pharmaceuticals, Novartis International AG, Pfizer Inc., Regeneron Pharmaceuticals, Sanofi S.A., and Valeant Pharmaceuticals International, Inc.. The robust drug pipeline shows that manufacturers see a large potential market for mild-to-moderate atopic dermatitis treatments. For instance, Anacor Pharmaceuticals is developing a drug, crisaborole which is a non-steroidal topical anti-inflammatory for mild-to-moderate atopic dermatitis which can have a significant utilization. Dupilumab is expected to be approved for the treatment of moderate to severe atopic dermatitis in adults.
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Mild To Moderate Atopic Dermatitis Treatment Market to Stand Tall from 2020 to 2030 NeighborWebSJ - NeighborWebSJ
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Eczema Skin-Care Products Market Provides In-Depth Analysis of the Industry, With Current Trends and Future Estimations to Elucidate The Investment…
Posted: at 12:25 am
IndustryGrowthInsights has published a latest market research report on Eczema Skin-Care Products market. The report provides a comprehensive scope of the market which caters enterprise to take critical business decisions. It consists of changing market trends, latest developments, growth opportunities, challenges, and detailed competitive analysis about the emerging and behemoth market players. This market research report also includes complete regional outlook and highlights top winning strategies that has helped industry players to expand their market share.
Eczema Skin-Care Products Market report gives out an in-depth analysis of the market scenario and covers the segmentation of the market in an insightful manner. IndustryGrowthInsights has congregated a massive amount of the data after monitoring the market for considerable amount of period and prepared the report for the forecast period 2020-2027. This report explains about the supply and demand scenario and assesses the possible changes in the market with the help of graphical representation to personify more clarity about the market.
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Market Research Report Covers Impacts of COVID-19 To The Market.
The COVID-19 pandemic has dramatically changed the dynamics of the Eczema Skin-Care Products market. This market research report includes extensive data on the impacts of the market. The research analyst team of the firm have been monitoring the market during this coronavirus crisis and has been talking with the industry experts to finally publish a detailed analysis about the future scope of the market. They have followed a robust research methodology and got involved in the primary and secondary research to prepare the Eczema Skin-Care Products market report.
This market report comprises of possible revenue growth, potential lucrative opportunities, product ranges, pricing factors, and parameters to confer the emerging and new entrants in the industry with a structured market data. This report encompasses the crucial government policies and regulations that significantly controls the Eczema Skin-Care Products market. Moreover, it includes the recent business agreements, mergers, acquisitions, partnerships, and even fallouts to provide the industry players with complete overview of the Eczema Skin-Care Products market.
The prominent Companies Covered in the Market Report
AveenoCeraVeLa Roche-PosayVanicreamAveenoFirst Aid BeautyNeutrogenaCetaphilDoveAll Mighty PacsTaoTronicsBestek
*Note: Additional players can be included in the list
Market Segmentation
By Product Type
Lotions and OintmentsCleansersDetergentsHumidifiersOthers
By Application
Online SalesOffline Sales
As per the report, the Eczema Skin-Care Products market is projected to reach a value of USDXX by the end of 2027 and grow at a CAGR of XX% through the forecast period (2020-2027). The report describes the current market trend of the Eczema Skin-Care Products in regions, covering North America, Latin America, Europe, Asia Pacific, and Middle East & Africa by focusing the market performance by the key countries in the respective regions.
This market segmentation analysis is expected to help the enterprise to strategize their product development strategies and marketing strategies in the region accordingly. IndustryGrowthInsights also offers customization of the report and provide quarterly/yearly updates on the report to help the enterprise to bring their A game.
You can buy the complete report @ https://industrygrowthinsights.com/checkout/?reportId=150870
The following is the TOC of the report:
Executive Summary
Assumptions and Acronyms Used
Research Methodology
Eczema Skin-Care Products Market Overview
Global Eczema Skin-Care Products Market Analysis and Forecast by Type
Global Eczema Skin-Care Products Market Analysis and Forecast by Application
Global Eczema Skin-Care Products Market Analysis and Forecast by Sales Channel
Global Eczema Skin-Care Products Market Analysis and Forecast by Region
North America Eczema Skin-Care Products Market Analysis and Forecast
Latin America Eczema Skin-Care Products Market Analysis and Forecast
Europe Eczema Skin-Care Products Market Analysis and Forecast
Asia Pacific Eczema Skin-Care Products Market Analysis and Forecast
Asia Pacific Eczema Skin-Care Products Market Size and Volume Forecast by Application
Middle East & Africa Eczema Skin-Care Products Market Analysis and Forecast
Why should you buy this report from us?
Our dedicated research team will be available 24/5 to you. They have been tracking the market since 2015 which has tremendously helped them to curate the Eczema Skin-Care Products market report. IndustryGrowthInsights just does not provide current/future market analysis but provide the enterprise with potential market avenues and revenues which is an ultimate game changer for a company.
We collaboratively work with the industry delegates to tailor the report. Over the years, we have carried out several interviews with the industry experts to provide a wholesome scope of the market. This market research report provides data in a comprehensive form with help of tables, statistics, and infographics. It offers detailed insights of the market to make crucial decisions in accordance to the present and future market scenario.
IndustryGrowthInsights gives a 360 view of the market which includes high growth opportunities, pitfalls, risk factors, latest advancements, and market drivers that helps the enterprise to create business strategies accordingly. This market research report provides distribution channel assessments, clients customers insights, entry level strategy, and innovation trends.
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Eczema Skin-Care Products Market Provides In-Depth Analysis of the Industry, With Current Trends and Future Estimations to Elucidate The Investment...
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A closer look at the AI hype machine: who really benefits? MercatorNet – MercatorNet
Posted: at 12:24 am
The poet Richard Brautigan said that one day we would all be watched over by machines of loving grace. It was a nice sentiment at the time. But I surmise Brautigan might have done a quick 180 if he was alive today. He would see how intelligent machines in general and AI in particular were being semi-weaponised or otherwise appropriated for purposes of a new kind of social engineering. He would also likely note how this process is usually positioned as something good for humanity in vague ways that never seem to be fully explained.
As both a technologist and a journalist, I find it very difficult to think of transhumanism and what Ill call the New Eugenics as anything less than deeply and literally dehumanising.
The hits, as they say, just keep on coming. Recently I ran across an article advising recent college graduates looking for jobs that they had better be prepared to have their facial expressions scanned and evaluated by artificial intelligence programs during and after interviews.
An article in the publication Higher Ed warned that:
Getting a job increasingly requires going through an interview on an AI platform If the proprietary technology [used to ] to evaluate the recordings concludes that a candidate does well in matching the demeanor, enthusiasm, facial expressions or word choice of current employees of the company, it recommends the candidate for the next round. If the candidate is judged by the software to be out of step, that candidate is not likely to move on.
If this were happening in China, of course, it would be much less surprising. You dont have to be a Harvard-trained psychiatrist to see that this kind of technology is violating some very basic human boundaries: how we think and feel and our innermost and private thoughts. And you dont have to be a political scientist to see that totalitarian societies are in the business of breaking down these boundaries for purposes of social and political control.
Facial recognition has already been implemented by some law enforcement agencies. Other technology being used for social control starts out in the corporate world and then migrates. Given the melding of corporate and government power thats taken place in the US over the last few decades, whats impermissible in government now can get fully implemented in the corporate world and then in the course of time bleeds over to government use via outsourcing and other mechanisms. Its a nifty little shell game. This was the case with the overt collection of certain types of data on citizens which was expressly forbidden by federal law. The way around it was to have corporations to do the dirty work and then turn around and sell the data to various government entities. Will we see the same thing happen with artificial intelligence and its ability to pry into our lives in unprecedented ways?
There is a kind of quasi-worship of technology as a force majeure in humanitys evolution that puts AI at the center of human existence. This line of thinking is now linked to the principles of transhumanism, a set of values and goals being pushed by Silicon Valley elites. This warped vision of techno-utopianism assures us that sophisticated computers are inherently superior to humans. Implicit in this view is the notion that intelligence (and one kind of intelligence at that) is the most important quality in the vast array of attributes that are the essential qualities of our collective humanity and longstanding cultural legacies.
The most hardcore transhumanists believe that our role is simply to step aside and assist in the creation of new life forms made possible by hooking up human brains to computers and the Internet, what they consider to be an evolutionary quantum leap. Unfortunately, people in powerful corporate positions like Ray Kurzweil, Googles Director of Engineering, and Elon Musk, founder of Neuralink, actually believe in these convoluted superhero mythologies. This line of thinking is also beginning to creep into the mainstream thanks to the corporate-driven hype put forth by powerful Silicon Valley companies who are pushing these ideas for profit and to maintain technologys ineluctable more, better, faster momentum.
The transhumanist agenda is a runaway freight train, barely mentioned in the mainstream media, but threatening to run over us all. In related mad science offshoot, scientists have succeeded in creating the first biological computer-based hybrids calledXenobotswhich theNew York Timesdescribes as programmable organisms that live for only about a week. The corporate PR frontage for these breakthroughs is always the same: they will only be used for the highest purposes like getting rid of plastics in the oceans.
But still the question remains: who will control or regulate the use of these man-made creatures?In the brave new world of building machines that can think and evolve on their own because they combine AI programming with biological programming, we have to ask where all this is headed. If machines are being used to evaluate us for job interviews, then why wont they be eventually used as police officers or judges? (In fact, Singapore is now using robotic dogs to police parks for Covid-related social distancing.)
As both a technologist and a journalist, I find it very difficult to think of transhumanism and what Ill call the New Eugenics as anything less than deeply and literally dehumanising. In the aftermath of WWII, eugenics used to be widely reviled when Nazi scientists experimented with and so highly valued it. Now its lauded as cutting-edge.
There are two ugly flies in this ointment. The first is the question of who directs and controls the AI machines being built. You can make a safe bet that it wont be you, your friends, or your neighbors but rather technocratic elites. The second is the fact that programmers, and their masters, the corporate Lords of Tech, are the least likely candidates to come up with the necessary wisdom to imbue AI with the deeper human qualities necessary to make it anything more than a force used for social and political control in conjunction with mass surveillance and other tools.
Another consideration is: how does politics fit into this picture? In the middle ages, one of the great power shifts that took place was from medieval rulers to the church. In the age of the enlightenment, another shift took place: from the church to the modern state. Now we are experiencing yet another great transition: a shift of power from state and federal political systems to corporations and, by extension, to the global elites that are increasingly exerting great influence on both, the 1 percenters that Bernie Sanders frequently refers to.
These trends have political implications because they have happened in tandem with the neoliberal sleight of hand that began with President Reagan. Gradually anti-democratic policy changes over a period of decades allowed elites to begin the process of transferring public funds to private coffers. This was done under the neoliberal smokescreen of widely touted but socially hollow benefits such as privatization, outsourcing, and deregulation bolstered by nostrums such as Government must get out of the way to let innovation thrive.
Behind the scenes, the use of advanced technology has played a strong role in enabling this transition but it did so out of the publics watchful eye. Now, it seems abundantly clear that technologies such as 5G, machine learning, and AI will continue to be leveraged by technocratic elites for the purposes of social engineering and economic gain. As Yuval Harari, one of transhumanisms most vocal proponents has stated:
Whoever controls these algorithms will bethe real government.
If AI is allowed to begin making decisions that affect our everyday lives in the realms of work, play and business, its important to be aware of who this technology serves: technologically sophisticated elites. We have been hearing promises for some time about how better advanced computer technology was going to revolutionise our lives by changing just about every aspect of them for the better. But the reality on the ground seems to be quite different than what was advertised. Yes, there are many areas where it can be argued that the use of computer and Internet technology has improved the quality of life.
But there are just as many others where it has failed miserably. Healthcare is just one example. Here misguided legislation combined with an obsession with insurance company-mandated data gathering has created massive info-bureaucracies where doctors and nurses spend far too much time feeding patient data into a huge information databases where it often seems to languish. Nurses and other medical professionals have long complained that too much of their time is spent on data gathering and not enough time focusing on healthcare itself and real patient needs.
When considering the use of any new technology, the question should be asked: whom does it ultimately serve? And to what extent are ordinary citizens allowed to express their approval or disapproval of the complex technological regimes being created that we all end up involuntarily depending upon? In a second Gilded Age where the power of billionaires and elites over our lives is now being widely questioned, what do we do about their ability to radically and undemocratically alter the landscape of our daily lives using the almighty algorithm?
Republished from Common Dreams and with the authors permission under a Creative Commons Attribution-Share Alike 3.0 License.
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A closer look at the AI hype machine: who really benefits? MercatorNet - MercatorNet
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