Daily Archives: February 8, 2021

Parasite infections may prevent aging and disease – Medical News Today

Posted: February 8, 2021 at 11:33 am

Through centuries of evolution, the human body and its surrounding environments have adapted to improve health and promote longevity. For example, the increasing emphasis on hygiene has been effective in combating parasites that cause disease.

These changes have been crucial, as evidenced by the greater life expectancies and lower disease rates in certain regions of the world. However, these benefits come with trade-offs.

Parasites and humans share a long history of coexistence. It is likely that the human immune function developed in relation to parasitic mechanisms.

The old friends hypothesis states that these parasites were like old friends of the human body that helped improve tolerance and function and that their decline led to a higher prevalence of allergic responses and autoimmune conditions.

This decline may also promote inflammaging, which is a chronic form of inflammation that worsens with progressing age. Inflammaging contributes to several age-related conditions, such as dementia, cancer, osteoporosis, and heart disease.

One recent study shows that inflammaging may exacerbate symptoms of COVID-19, as well.

Bruce Zhang and Dr. David Gems, from the Institute of Healthy Ageing at University College London in the United Kingdom, conducted a review of the existing literature to explore the use of parasite worms as a therapy to reverse conditions linked to inflammaging. This review article appears in the journal eLife.

The authors focused their research on a specific group of parasitic worms called helminths, which include roundworms, tapeworms, and flukes. These parasites live inside host organisms, such as human bodies, and take advantage of their immune responses in order to survive.

These findings also provide a glimpse into the intricacies of the human bodys immune functions.

Scientists associate the decline of helminths with multiple inflammatory conditions that occur earlier in life. These include asthma, eczema, multiple sclerosis (MS), rheumatoid arthritis, inflammatory bowel disease, and type 1 diabetes.

Current evidence supports the idea that both natural and deliberate infection with helminths can combat these inflammatory conditions.

Indeed, in 1976, researcher J. A. Turton published a report in which he explained that his hookworm infection reduced the severity of his allergies.

A more recent study which Marc Charabati, of the University of Montreal in Canada, led showed that infecting mice with helminths eased their MS symptoms.

Although these findings suggest that restorative helminth therapy may address pre-aging inflammatory conditions, the question of whether or not it can prevent conditions that occur in older age remains.

A key characteristic of inflammaging is a consistent increase in pro-inflammatory proteins in the blood. Multiple experiments have shown that helminth infection can suppress levels of these pro-inflammatory proteins.

In contrast, administering anthelmintic treatments which can kill helminths increased the inflammatory response of these proteins.

Although the direct administration of helminths can be beneficial, it can also cause undesired infections. A viable alternative is to utilize the molecular components of helminth mechanisms.

One experiment, which Jenny Crowe and others at the University of Glasgow in the U.K. conducted, incorporated this concept in a mouse model that ate a high calorie diet. Specifically, the team administered a protein called ES-62, which is an anti-inflammatory molecule derived from roundworm secretion.

They found that ES-62 prevented both the degradation of the gut barrier and the enlargement of fat tissue, which are mechanisms that contribute to inflammaging.

The mice also showed a 12% increase in their median lifespan. This suggests that ES-62 was able to suppress inflammaging and limit health-related age acceleration.

Similar studies have indicated the effectiveness of helminths and helminth-secreted products in protecting against rheumatoid arthritis, atherosclerosis, and type 2 diabetes.

There is also some evidence that points to helminth therapy in cancer resistance. A few studies in mice have shown that tapeworms prevented the formation of colon tumors.

However, it is important to note that certain helminths can cause cancer, as well. For example, the trematode parasite Schistosoma haematobium can cause bladder cancer.

Although these studies do not confirm that helminths can directly reduce inflammaging, they do show the ability of helminths to protect against the processes that ultimately lead to it.

Zhang and Dr. Gems raise important questions regarding helminth therapy research. These include: What are optimal ages to apply such therapy to reduce inflammaging? Would helminth therapy act only in a preventive fashion (typical of anti-aging treatments), or could it reverse existing disease symptoms?

They also state the necessity of understanding the pathways that shape anti-inflammaging properties.

As Dr. Gems says, In the wake of successes during the last century in eliminating the evils of helminth infections, the time now seems propitious to explore further their possible benefits, particularly for our aging population strange though this may sound.

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Parasite infections may prevent aging and disease - Medical News Today

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Global Longevity and Anti-senescence Therapy Market Report 2020 by Key Players, Types, Applications, Countries, Market Size, Forecast to 2026 (Based…

Posted: at 11:33 am

Overview for Longevity and Anti-senescence Therapy Market Helps in providing scope and definitions, Key Findings, Growth Drivers, and Various Dynamics.

Longevity and Anti-senescence Therapy Market Data and Acquisition Research Study with Trends and Opportunities 2019-2024The study of Longevity and Anti-senescence Therapy market is a compilation of the market of Longevity and Anti-senescence Therapy broken down into its entirety on the basis of types, application, trends and opportunities, mergers and acquisitions, drivers and restraints, and a global outreach. The detailed study also offers a board interpretation of the Longevity and Anti-senescence Therapy industry from a variety of data points that are collected through reputable and verified sources. Furthermore, the study sheds a lights on a market interpretations on a global scale which is further distributed through distribution channels, generated incomes sources and a marginalized market space where most trade occurs.

Along with a generalized market study, the report also consists of the risks that are often neglected when it comes to the Longevity and Anti-senescence Therapy industry in a comprehensive manner. The study is also divided in an analytical space where the forecast is predicted through a primary and secondary research methodologies along with an in-house model.

Download PDF Sample of Longevity and Anti-senescence Therapy Market report @ https://hongchunresearch.com/request-a-sample/113635

Key players in the global Longevity and Anti-senescence Therapy market covered in Chapter 4:Acorda TherapeuticsUnity BiotechnologyAntoxereneCelgeneCohbarSenex BiotechnologyHuman Longevity Inc.T.A. SciencesAgex TherapeuticsRecursion PharmaceuticalsCalico Life SciencesSpotlight BiosciencePowervision Inc.Sierra Sciences LlcRestorbioInsilico MedicineOisin BiotechnologySenolytic TherapeuticsProteostasis Therapeutics Inc.Prana Biotechnology Ltd.Cleara Biotech

In Chapter 11 and 13.3, on the basis of types, the Longevity and Anti-senescence Therapy market from 2015 to 2026 is primarily split into:Senolytic Drug TherapyGene TherapyImmunotherapyOthers

In Chapter 12 and 13.4, on the basis of applications, the Longevity and Anti-senescence Therapy market from 2015 to 2026 covers:LongevitySenescence InhibitionCardiovascular DiseasesNeural Degenerative DiseasesOphthalmology DisordersCancer

Geographically, the detailed analysis of consumption, revenue, market share and growth rate, historic and forecast (2015-2026) of the following regions are covered in Chapter 5, 6, 7, 8, 9, 10, 13:North America (Covered in Chapter 6 and 13)United StatesCanadaMexicoEurope (Covered in Chapter 7 and 13)GermanyUKFranceItalySpainRussiaOthersAsia-Pacific (Covered in Chapter 8 and 13)ChinaJapanSouth KoreaAustraliaIndiaSoutheast AsiaOthersMiddle East and Africa (Covered in Chapter 9 and 13)Saudi ArabiaUAEEgyptNigeriaSouth AfricaOthersSouth America (Covered in Chapter 10 and 13)BrazilArgentinaColumbiaChileOthersRegional scope can be customized

For a global outreach, the Longevity and Anti-senescence Therapy study also classifies the market into a global distribution where key market demographics are established based on the majority of the market share. The following markets that are often considered for establishing a global outreach are North America, Europe, Asia, and the Rest of the World. Depending on the study, the following markets are often interchanged, added, or excluded as certain markets only adhere to certain products and needs.

Here is a short glance at what the study actually encompasses:Study includes strategic developments, latest product launches, regional growth markers and mergers & acquisitionsRevenue, cost price, capacity & utilizations, import/export rates and market shareForecast predictions are generated from analytical data sources and calculated through a series of in-house processes.

However, based on requirements, this report could be customized for specific regions and countries.

Brief about Longevity and Anti-senescence Therapy Market Report with [emailprotected]https://hongchunresearch.com/report/longevity-and-anti-senescence-therapy-market-size-2020-113635

Some Point of Table of Content:

Chapter One: Report Overview

Chapter Two: Global Market Growth Trends

Chapter Three: Value Chain of Longevity and Anti-senescence Therapy Market

Chapter Four: Players Profiles

Chapter Five: Global Longevity and Anti-senescence Therapy Market Analysis by Regions

Chapter Six: North America Longevity and Anti-senescence Therapy Market Analysis by Countries

Chapter Seven: Europe Longevity and Anti-senescence Therapy Market Analysis by Countries

Chapter Eight: Asia-Pacific Longevity and Anti-senescence Therapy Market Analysis by Countries

Chapter Nine: Middle East and Africa Longevity and Anti-senescence Therapy Market Analysis by Countries

Chapter Ten: South America Longevity and Anti-senescence Therapy Market Analysis by Countries

Chapter Eleven: Global Longevity and Anti-senescence Therapy Market Segment by Types

Chapter Twelve: Global Longevity and Anti-senescence Therapy Market Segment by Applications 12.1 Global Longevity and Anti-senescence Therapy Sales, Revenue and Market Share by Applications (2015-2020) 12.1.1 Global Longevity and Anti-senescence Therapy Sales and Market Share by Applications (2015-2020) 12.1.2 Global Longevity and Anti-senescence Therapy Revenue and Market Share by Applications (2015-2020) 12.2 Longevity Sales, Revenue and Growth Rate (2015-2020) 12.3 Senescence Inhibition Sales, Revenue and Growth Rate (2015-2020) 12.4 Cardiovascular Diseases Sales, Revenue and Growth Rate (2015-2020) 12.5 Neural Degenerative Diseases Sales, Revenue and Growth Rate (2015-2020) 12.6 Ophthalmology Disorders Sales, Revenue and Growth Rate (2015-2020) 12.7 Cancer Sales, Revenue and Growth Rate (2015-2020)

Chapter Thirteen: Longevity and Anti-senescence Therapy Market Forecast by Regions (2020-2026) continued

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List of tablesList of Tables and Figures Table Global Longevity and Anti-senescence Therapy Market Size Growth Rate by Type (2020-2026) Figure Global Longevity and Anti-senescence Therapy Market Share by Type in 2019 & 2026 Figure Senolytic Drug Therapy Features Figure Gene Therapy Features Figure Immunotherapy Features Figure Others Features Table Global Longevity and Anti-senescence Therapy Market Size Growth by Application (2020-2026) Figure Global Longevity and Anti-senescence Therapy Market Share by Application in 2019 & 2026 Figure Longevity Description Figure Senescence Inhibition Description Figure Cardiovascular Diseases Description Figure Neural Degenerative Diseases Description Figure Ophthalmology Disorders Description Figure Cancer Description Figure Global COVID-19 Status Overview Table Influence of COVID-19 Outbreak on Longevity and Anti-senescence Therapy Industry Development Table SWOT Analysis Figure Porters Five Forces Analysis Figure Global Longevity and Anti-senescence Therapy Market Size and Growth Rate 2015-2026 Table Industry News Table Industry Policies Figure Value Chain Status of Longevity and Anti-senescence Therapy Figure Production Process of Longevity and Anti-senescence Therapy Figure Manufacturing Cost Structure of Longevity and Anti-senescence Therapy Figure Major Company Analysis (by Business Distribution Base, by Product Type) Table Downstream Major Customer Analysis (by Region) Table Acorda Therapeutics Profile Table Acorda Therapeutics Production, Value, Price, Gross Margin 2015-2020 Table Unity Biotechnology Profile Table Unity Biotechnology Production, Value, Price, Gross Margin 2015-2020 Table Antoxerene Profile Table Antoxerene Production, Value, Price, Gross Margin 2015-2020 Table Celgene Profile Table Celgene Production, Value, Price, Gross Margin 2015-2020 Table Cohbar Profile Table Cohbar Production, Value, Price, Gross Margin 2015-2020 Table Senex Biotechnology Profile Table Senex Biotechnology Production, Value, Price, Gross Margin 2015-2020 Table Human Longevity Inc. Profile Table Human Longevity Inc. Production, Value, Price, Gross Margin 2015-2020 Table T.A. Sciences Profile Table T.A. Sciences Production, Value, Price, Gross Margin 2015-2020 Table Agex Therapeutics Profile Table Agex Therapeutics Production, Value, Price, Gross Margin 2015-2020 Table Recursion Pharmaceuticals Profile Table Recursion Pharmaceuticals Production, Value, Price, Gross Margin 2015-2020 Table Calico Life Sciences Profile Table Calico Life Sciences Production, Value, Price, Gross Margin 2015-2020 Table Spotlight Bioscience Profile Table Spotlight Bioscience Production, Value, Price, Gross Margin 2015-2020 Table Powervision Inc. Profile Table Powervision Inc. Production, Value, Price, Gross Margin 2015-2020 Table Sierra Sciences Llc Profile Table Sierra Sciences Llc Production, Value, Price, Gross Margin 2015-2020 Table Restorbio Profile Table Restorbio Production, Value, Price, Gross Margin 2015-2020 Table Insilico Medicine Profile Table Insilico Medicine Production, Value, Price, Gross Margin 2015-2020 Table Oisin Biotechnology Profile Table Oisin Biotechnology Production, Value, Price, Gross Margin 2015-2020 Table Senolytic Therapeutics Profile Table Senolytic Therapeutics Production, Value, Price, Gross Margin 2015-2020 Table Proteostasis Therapeutics Inc. Profile Table Proteostasis Therapeutics Inc. Production, Value, Price, Gross Margin 2015-2020 Table Prana Biotechnology Ltd. Profile Table Prana Biotechnology Ltd. Production, Value, Price, Gross Margin 2015-2020 Table Cleara Biotech Profile Table Cleara Biotech Production, Value, Price, Gross Margin 2015-2020 Figure Global Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Global Longevity and Anti-senescence Therapy Revenue ($) and Growth (2015-2020) Table Global Longevity and Anti-senescence Therapy Sales by Regions (2015-2020) Table Global Longevity and Anti-senescence Therapy Sales Market Share by Regions (2015-2020) Table Global Longevity and Anti-senescence Therapy Revenue ($) by Regions (2015-2020) Table Global Longevity and Anti-senescence Therapy Revenue Market Share by Regions (2015-2020) Table Global Longevity and Anti-senescence Therapy Revenue Market Share by Regions in 2015 Table Global Longevity and Anti-senescence Therapy Revenue Market Share by Regions in 2019 Figure North America Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Europe Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Asia-Pacific Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Middle East and Africa Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure South America Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure North America Longevity and Anti-senescence Therapy Revenue ($) and Growth (2015-2020) Table North America Longevity and Anti-senescence Therapy Sales by Countries (2015-2020) Table North America Longevity and Anti-senescence Therapy Sales Market Share by Countries (2015-2020) Figure North America Longevity and Anti-senescence Therapy Sales Market Share by Countries in 2015 Figure North America Longevity and Anti-senescence Therapy Sales Market Share by Countries in 2019 Table North America Longevity and Anti-senescence Therapy Revenue ($) by Countries (2015-2020) Table North America Longevity and Anti-senescence Therapy Revenue Market Share by Countries (2015-2020) Figure North America Longevity and Anti-senescence Therapy Revenue Market Share by Countries in 2015 Figure North America Longevity and Anti-senescence Therapy Revenue Market Share by Countries in 2019 Figure United States Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Canada Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Mexico Longevity and Anti-senescence Therapy Sales and Growth (2015-2020) Figure Europe Longevity and Anti-senescence Therapy Revenue ($) Growth (2015-2020) Table Europe Longevity and Anti-senescence Therapy Sales by Countries (2015-2020) Table Europe Longevity and Anti-senescence Therapy Sales Market Share by Countries (2015-2020) Figure Europe Longevity and Anti-senescence Therapy Sales Market Share by Countries in 2015 Figure Europe Longevity and Anti-senescence Therapy Sales Market Share by Countries in 2019 Table Europe Longevity and Anti-senescence Therapy Revenue ($) by Countries (2015-2020) Table Europe Longevity and Anti-senescence Therapy Revenue Market Share by Countries (2015-2020) Figure Europe Longevity and Anti-senescence Therapy Revenue Market Share by Countries in 2015 Figure Europe Longevity and Anti-senescence Therapy Revenue Market Share by Countries in 2019 Figure Germany Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure UK Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure France Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Italy Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Spain Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Russia Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Asia-Pacific Longevity and Anti-senescence Therapy Revenue ($) and Growth (2015-2020) Table Asia-Pacific Longevity and Anti-senescence Therapy Sales by Countries (2015-2020) Table Asia-Pacific Longevity and Anti-senescence Therapy Sales Market Share by Countries (2015-2020) Figure Asia-Pacific Longevity and Anti-senescence Therapy Sales Market Share by Countries in 2015 Figure Asia-Pacific Longevity and Anti-senescence Therapy Sales Market Share by Countries in 2019 Table Asia-Pacific Longevity and Anti-senescence Therapy Revenue ($) by Countries (2015-2020) Table Asia-Pacific Longevity and Anti-senescence Therapy Revenue Market Share by Countries (2015-2020) Figure Asia-Pacific Longevity and Anti-senescence Therapy Revenue Market Share by Countries in 2015 Figure Asia-Pacific Longevity and Anti-senescence Therapy Revenue Market Share by Countries in 2019 Figure China Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Japan Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure South Korea Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Australia Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure India Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Southeast Asia Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Middle East and Africa Longevity and Anti-senescence Therapy Revenue ($) and Growth (2015-2020) continued

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Global Longevity and Anti-senescence Therapy Market Report 2020 by Key Players, Types, Applications, Countries, Market Size, Forecast to 2026 (Based...

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Wittgenstein, Popper and the poker – TheArticle

Posted: at 11:32 am

On the afternoon of October 25, 1946, the philosopher Ludwig Wittgenstein held a graduate seminar in his rooms at the University of Cambridge. The discussion centred around the issue of what it means to say that you talk to yourself. Ironically (given the subject matter), as was typical of his seminars, it was a conversation carried out in silence. Wittgenstein was more a collector of acolytes than students. Most of whom were a bit scared of him.

Later that day, he attended a packed meeting of the universitys Moral Sciences Club. During this he threatened the visiting speaker, Karl Popper, with a fireplace poker.

Or did he?

The details of what happened that evening are charmingly interrogated by David Edmonds and John Eidenow in their 2001 book Wittgensteins Poker. The verdict? That Wittgenstein may or may not have been guilty of a failure of donnish etiquette (or attempted assault). The Edmonds-Eidenow prosecution file is an agreeable condensation of most of the historical issues. I cant recommend it highly enough. It is a beautifully written portrait of the idiosyncrasies of the main protagonists (including Bertrand Russell no show without Punch), and a faithful characterisation of the other witnesses/attendees a sort of carnival of philosophical grotesques.

Wittgensteins Poker is wonderful psychology but incomplete philosophy. Wittgenstein was a scion of one of the wealthiest families in Austria; Popper was a member of the more professional Viennese classes. He was the deeply ambitious up-and-coming philosopher of science; Wittgenstein, at that point in his career (he died five years later), didnt think philosophy was a thing. A deeply serious person (and a very practically minded one) he considered it a diversion, one which merits little more attention than a crossword puzzle. Its alleged that this incident instantiated a feud its more likely that whilst Popper still wrote about it several decades later, Wittgenstein had forgotten about it ten minutes after it happened. Genius tends towards solipsism. The book brings all this out very well. But it misses a trick.

Poppers paper was titled Are there problems in philosophy?. Youd think it would be self-evident that there are, but we who are trained to argue about everything will end up arguing about anything. Wittgensteins view was that the huge philosophical issues are no such thing, that they are instead illusions thrown up by our systematic misuse of language. Just as the Buddha thought we can be tricked into a fake view of the universe by getting our words out in the wrong order, so Wittgenstein thought that the deepest questions that trouble the human mind are caused by a certain slovenliness about the way we speak and (therefore) think.

How do you seriously answer questions about whether other people have minds, whether God exists, or what it makes something true rather than false? Wittgensteins answer was that you dont take the question seriously in the first place. The deepest questions of philosophy are best addressed not by argument but by therapy. Our ways of thinking imply that what we take to be deeply counter-intuitive is probably no more than linguistic mischief, a mischief in which we collude. Just as the early Church argued that as soon as we act, we display our tendency to sin, so Wittgenstein believed that as soon as we start philosophising, we go deeply wrong.

But there is something obviously wrong here, isnt there? You could argue that Wittgenstein is guilty of a form of self-refutation, and that the position he advances is, in itself, a redolently philosophical one. The claim that there are no really interesting philosophical problems is surely contentious? And, if contentious, then its a metaphysical claim?

More interestingly, what happened on that evening is in itself a question with some philosophical import. Who was right?

What, in other words, is the status of propositions which make claims about the past? Wittgenstein, in an earlier iteration, had sided himself with the Vienna Circle of philosophers who wished to assimilate all knowledge to what can or cannot be empirically verified. Their manifesto announced a theory of language according to which a statement can only be meaningful, as opposed to true, to the extent that it can be subject to some experiment. The logical positivists had declared war on speculative metaphysics (dangerous to the scientistic agenda) without noticing that their own position was hilariously self-refuting. How do you verify its own articles of agenda? And how, more interestingly, can you maintain that statements concerning what happened five minutes ago let alone 75 years ago are meaningful?

Popper made his name dismantling that theory of meaning. So maybe we should score that one to him?

One thing we do know, is that this was the first and only time these two ever met. Unless, of course, theyre chatting now. Thatd be a Round 2 worth watching. Wittgenstein talking to himself; Popper irate that hes being ignored.

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Exclusive: PokerStars Michigan is the Largest Regulated Online Poker Room in the United States Right Now – Pokerfuse

Posted: at 11:32 am

According to the latest cash game traffic figures, seen exclusively by pokerfuse, PokerStars.MI is right now the largest regulated real money online poker network in the USlarger than the combined WSOP/888 network, bigger even than its Pennsylvania counterpart, PokerStars PA.

PokerStars launched its online poker room in Michigan ten days ago. It is the third regulated online poker site in the US ran by the company, following on from its 2016 launch in New Jersey and its late 2019 debut in Pennsylvania.

All three online poker rooms are segregatedmeaning the player pools are not connected together, nor with the global dot-com player liquidity. Yet despite this, thousands of players from Michigan statepopulation approximately 10 millionhave flocked to the new online poker room.

This has resulted in one of the highest traffic levels ever observed by any online poker room in the US regulated markets at any time in history.

PokerStars USA: The worlds largest online poker room is legal and regulated in Pennsylvania, Michigan and New Jersey!

According to figures tracked by GameIntel, formerly PokerScout, the go-to source for independent tracking of online poker traffic, licensed exclusively by pokerfuses Poker Industry PRO, PokerStars Michigan has averaged 410 concurrent cash game players over the last week.

To put that in perspective, PokerStars PAwhere PokerStars is also the only operator, and in a state with population 30% largerwas a tiny pip below, recording 405 players. PokerStars NJ was a third the size, at approximately 140 average seats.

Its nearest competitor in the United States, the WSOP/888 US Networkwhich comprises six online poker rooms sharing liquidity between New Jersey, Nevada and Delawarereported 275 cash game seats.

All figures are based on average concurrent cash game traffic observed over the last seven days, rounded to the nearest 5 seats. All data used under license from GameIntel.com via the Poker Industry PRO Data platform.

WSOP/888, which has been active in Nevada since 2013, has only ever hit 400 concurrent cash game seats one time in its near eight-year history: Briefly for a few weeks last year in the spring in the first wave of the coronavirus pandemic.

PokerStars NJ has never got close to the level: Not even when it first launched in 2016, including a period where it was #1 in the market; nor even during last years global online poker explosionthere, it hit its all-time peak of 330 concurrent seats.

In fact, the only online poker room in the US to consistently report this level of traffic is PokerStars Pennsylvania. Since launch in November 2019, the network has hovered around the 400 seats mark. It briefly saw its traffic explode up to 1000 during the absolute highs of the Covid-fueled online poker boom.

Data provided by GameIntel

While cash game traffic statistics always give the most comprehensive view of the online poker market, the numbers out of the tournaments also show that PokerStars Michigan is enjoying a strong turnoutthough spots are starting to show in the operators aggressive weekend schedule, and the first big overlay has been seen.

As pokerfuse reported last week, its first weekend saw a decent turnout to its Sunday Majors, with all guarantees covering easily. The Sunday Warm-Up, in particular, attracted a strong showing of over 300 entries.

Clearly buoyed by this success, PokerStars MI increased guarantees for the second weekend. Three of the four highlight tournaments saw bumps to their guarantees, and the site also unveiled the Sunday Special: Its new flagship event with a $100 buy-in and a $20,000 guarantee.

The Special certainly had a huge first outing. In total, it brought in 301 entries, generating a prize pool of $27,632by far the largest in the state so far.

However, this did notably have a knock-on effect on other tournaments. The $50 Supersonic grew, easily surpassing its new $2500 with 85 entries to generate a prize pool of almost $400. However, the others saw dips.

The Storm dropped a few entries, but easily covered. The Warm Up was actually affected quite a lot, losing 112 entriesthought it still handily covered its $5000 guarantee.

But it was the High Roller that really suffered. On the first week, it attracted 63 entries to almost double its $7500 guarantee. Understandably, PokerStars then upped the guarantee to $10,000 for its second outing. However, yesterday it attracted just 36 entries, generating prize money of $8388an overlay of $1612.

This could well be the first overlay in Michigan, and it is not a small one. Those 36 entrants certainly enjoyed some valueto the tune of almost $50 each.

The likely reasons for this are twofold: Firstly, the $100 Special will have attracted some players to that instead. Overall, the Sunday Majors generated prize money of almost $50,000, way more than the $28,000 in the opening weekendso the level of spend has not dropped; it just shifted.

However, yesterday was also unique in that it was Superbowl Sunday. This often has impact on tournament turnoutso this could well be a one-off.

Either way, players should keep watch on next Sundays tournaments, as there could be value opportunities.

Meanwhile, all eyes are now on the first big tournament series to be announced by PokerStars MI, details of which could come this week. Pokerfuse has predicted that it could be the first ever MICOOP, which could have a total series guarantee of up to $1 million. Watch this space.

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Exclusive: PokerStars Michigan is the Largest Regulated Online Poker Room in the United States Right Now - Pokerfuse

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Is Tony G Looking to Return to the Poker World? – Poker News Daily

Posted: at 11:32 am

Hes had one of the more impressive runs in the world of poker. Hes also been able to make an impact on the international politics stage. But, after several years away from the game, is Antanas Tony G Guoga looking to return to the poker world on a full-time basis?

End of His Political Career Could Signal Change

According to casino journalist Rose Varrelli in Australia, the end of Guogas time in the European Parliament might be signaling a change in course for the poker provocateur. In 2016, Guoga ran for and was elected to a seat in the European Parliament, the legislative body for the European Union. After three years on that esteemed board, Guoga lost in a reelection bid but was able to run for and win a seat in the Lithuanian Parliament (Guoga has dual Lithuanian/Australian citizenship as he was born in Lithuania and moved at the age of 11 to Australia). The poker professional has been apparently thinking of his place in both politics and poker since taking the Lithuanian Parliament seat.

In mid-January Guoga, allegedly citing his lack of influence on politics in the body, resigned his Parliament seat. Other information coming out, however, indicated he was not pleased with the direction of the Labor Party leadership in the Lithuanian Parliament. This dissatisfaction came out after several comments from the partys chairman, Viktor Uspaskich, on several hot button issues.

Guoga made it official in a Tweet to his followers:

Could Guoga Adapt to Todays Game?

There are some in the poker world that would say that the game has changed since Guoga once was a part of it. Even though he has been a part of the political spectrum for several years, Guoga hasnt completely dropped playing the game. In fact, some of his biggest on the felt success has come over the last few years.

2019 was the biggest earnings year of his career, taking down more than $1.1 million in earnings from tournaments primarily in Europe. Guoga won the partypoker MILLIONS Short Deck High Roller tournament in August 2019, earning him $265,859 for his efforts, but that was just a warmup. In Rozvadov at the Super High Roller event (250,000) for the World Series of Poker Europe, Guoga took down fourth place for the biggest payday of his career, more than $880,000 (U. S.).

The fingerprints of Guoga on the world of poker are all over the place. He was the founder of PokerNews back in the early Aughts (before selling the operation to The Stars Group in the late 2010s), which arguably ushered in the age of online poker news operations. But it was his play on the tables and his aggressive, combative nature that drew people to the character Tony G.

He would be a part of several verbal sparring matches when he was at his peak on the tables. One in particular was a particularly tense verbal barrage with Russias Ralph Perry during the International Poker Championships. It was this battle where Guogas catchphrase On yer bike! (used to summarily dismiss Perry from the table) came into the lexicon.

The question would be is whether the game has passed Guoga by or not. Although his success in 2019 was the best of his career, it was in high roller tournaments, not in normal Main Event battles with larger fields. Theres also the factor that Guoga, much like many other poker players, has basically had to sit on the sidelines in 2020 due to the COVID pandemic. How much Tony G might be able to add to his $7 million-plus career earnings in a new age of poker play is unknown, but his personality would be a change in the current state of the game.

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Is Tony G Looking to Return to the Poker World? - Poker News Daily

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High Stakes Poker S8 E8: Find Out Which Player Went Broke & Quit the Game – PokerNews.com

Posted: at 11:32 am

February 04, 2021Chad Holloway

Wednesday's latest "High Stakes Poker" episode on PokerGO was a continuation of the last weeks game, which was played $200/$400/$800 w/ an $800 ante from the third blind.

The episode started with six players in their seats while Tom Dwan was sitting out. Heres how things stack up at the top of the broadcast:

In the first hand of the new episode, Damien Leforbes raised to $2,500 from middle position with the and the ever-aggressive Michael Schwimer three-bet to $9,000 from the cutoff holding the . Action folded back to Leforbes and he called to see the flop, which gave Schwimer trip eights.

Leforbes check-called a bet of $6,000 and then check-called one of $15,000 on the turn. The river was gin for Leforbes, who checked his full house. Schwimer bet $24,000, which left him just $21,000 behind, and Leforbes check-raised all in.

Did you get lucky as shit on me? a seemingly-frustrated Schwimer asked before calling off and discovering the bad news.

I will not apologize for running good, said Leforbes as he pulled in the $153,400 pot.

After reloading to $100,000, Schwimer raised to $3,000 from the hijack and Dwan, who had returned to the game, three-bet to $13,000 from the small blind. Schwimer called, the flop fell . Dwan continued for $14,000 and Schwimer, who flopped top two pair, just called to see the turn.

Dwan made top pair but still checked, and Schwimer followed suit. On the river, Dwan bet $25,000 and Schwimer leaned back in his chair while letting out a big sigh before saying, All in.

It was $73,000 total and Dwan hit the tank.

Didnt snap-call, Im in pretty good shape, Schwimer claimed. Dwan thought long and hard before paying it off, and just like that Schwimer doubled back by claiming the $200,800 pot.

Dwan opened for $2,500 with the and Sean Perry looked down at the next to act. He three-bet to $8,000 and then Jean-Robert Bellande, who had lost a six-figure pot to Dwan the hand prior, four-bet to $30,000 out of the small blind with the .

Dwan folded and Perry, the son of poker pro Ralph Perry, paused for a few beats before five-betting to $70,000. Bellande asked how much his opponent had behind, which was $246,000, and Bellande opted to call.

He flopped top pair on the flop and checked it over to Perry, who bet $40,000 into the pot of $144,100. Bellande called and then check-called a bet of $70,000 when the turn gave him an open-ended straight draw.

After the paired the board on the river, Bellande checked for the third time and Perry moved all in for his last $136,000. Bellande asked for a count and realized he had the bigger stack, albeit by a slim margin of $18,000. Eventually, Bellande called only to see his opponent table the goods.

With that, Perry doubled in a juicy pot worth $637,700.

After Rick Salomon left the game, a new player joined the game in Bryn Kenney, who bought in with a massive stack. Heres how this stacked up at that point in time:

In his first hand of this episode, Kenney raised to $4,000 from the cutoff with the and Perry called from the big blind with the . The flop gave Perry trip eights and he check-called a bet of $10,000.

Perry checked again on the turn, which gave him a full house, and Kenney continued to bluff by firing out $23,000. Perry just called and then checked yet again on the river. Kenney took the bait and triple-barreled it with a bet of $64,000, but had to fold when Perry finally woke up with the check-raise to $219,000. Kenney took an early hit while Perry collected another big pot, this one worth $359,8000.

In the penultimate hand of the episode, John Andress had the $1,600 straddle on and both Dwan and Bellande called, the former under the gun and the latter on the button. Schwimer then raised to $4,000 with the in the small blind and Kenney called from the big with the . All the aforementioned players called and it was five-way action to the flop.

Schwimer continued for $15,000 with top pair and Kenney raised to $52,000 with his set. Andress folded, Dwan gave up his flush draw, and Bellande got out of the way. Schwimer called and the turn gave him a wheel draw, which he checked.

Kenney bet $71,000, Schwimer called, and the completed the board on the river. Schwimer improved to two pair but checked to Kenney, who bet $165,000. Schwimer snap-called off his stack and then let loose some expletives upon seeing Kenney had the best hand to win the $597,200 pot.

Alright, that was fun boys, Schwimer told the table before giving up his seat in the game.

Remember, High Stakes Poker will air every Wednesday but is only available to PokerGO subscribers. If youre not currently subscribed, you can get a monthly subscription for $14.99, a three-month plan for $29.99, and an annual subscription for $99.99.

*Images courtesy of PokerGO.

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Longtime Poker Pro Ricardo Eyzaguirre Reflects on Career Year in 2020 – PokerNews.com

Posted: at 11:32 am

February 06, 2021Chad Holloway

The COVID-19 pandemic decimated live tournament poker in 2020. There were several events in January and February before things shut down in March, and from August onward there were a spattering of events to be had in states that would allow it. Through the limited schedule, a handful of players managed to strike it big including Floridas Ricardo Eyzaguirre.

The 31-year-old originally from Lima, Peru, was one of 2020s breakout stars. He enjoyed a career year winning $434,771 including two big wins at the Seminole Hard Rock in Hollywood, Florida, which recently played host to the 2021 Lucky Hearts Poker Open.

First, he took down the $1,100 October Anniversary Special for $46,000 and a month later won the $1,100 November Holiday Special for $47,000. However, his largest score of 2020 came in January when he finished runner-up in the Borgata Winter Poker Open Event #1: $600 Kick-Off for a career-high $290,000.

My greatest accomplishment to date would be my first six-figure score at Borgata at the beginning of the year, Eyzaguirre said. It really felt like my hard work paid off and I was really anxious and working hard to reach that goal.

Eyzaguirre immigrated to the United States with his mother and three brothers when he was just 10 years old. Now, two decades later, he is a father to two children of his own Ricardo Jr. and Violet. He first learned to play poker at the age of 18 in his brothers home game, and from there he visited local casinos in the Miami area.

Ive been playing poker professionally for about 14 years, he told PokerNews. For the first 10 years, I only played cash games in south and central Florida. Then, in about 2015, I started playing tournaments.

Indeed, in addition to a full tournament schedule, Eyzaguirre dukes it out at $2-$5 and $5-$10 no-limit holdem cash game tables as well as some high-stakes pot-limit Omaha online.

Im a very dedicated person and Im very goal-driven, he said. 2020 was defiantly a weird and troubling year although I feel like it was my breakout year and when all my hard work significantly paid off. With COVID hurting the whole world and so much suffering it is hard to call it a great year, but Im definitely thankful for my scores and look forward to working as hard as I can to have many other years like this one in the future.

Like many others, Eyzaguirre has a goal of winning a World Series of Poker bracelet, which would go nicely with his pair of gold rings. Back in 2017, he won the WSOP Circuit Harrahs Cherokee Event #7: $365 Monster Stack for $74,853, and two years later in December 2019 he won Event #13: $400 NLH Double Stack for $31,386 at the same venue.

Im a very competitive person, Eyzaguirre revealed. I really enjoy playing poker as a career and working on my trade. I attribute my success this year to studying, hard work, dedication, and perseverance.

He concluded: Lastly, I have a very tight family I want to thank my mother for being the best mom I can ask for and always being for me to support me. Im looking forward to playing a lot and learning a lot this year so hopefully, PokerNews will be seeing a lot more of me. Im going to give it all I got!

For those looking to follow Eyzaguirres poker journey, you can follow him on Twitter @ricardoeyz222.

*Images courtesy of WSOP and Seminole Hard Rock.

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New Poker Documentary Smile Honors the Life of the Late Thor Hansen – PokerNews.com

Posted: at 11:32 am

February 03, 2021Chad Holloway

When you think of the Godfather of Poker, you probably think of Doyle Brunson. However, when it comes to being the Godfather of Norwegian Poker, that honor goes to the late Thor Hansen, who passed away in 2018 at the age of 71 after a prolonged battle with cancer.

Hansen, who many believe is worthy of the Poker Hall of Fame, was active in poker while he fought the cancer, and while those in the know were aware of his health issues, the larger poker community wasnt. Now, more than two years after his death, Hansens story is being told in the new poker documentary Smile by filmmakers Kari Wle and Linn Amundsen.

The 75-minute film is available now on Vimeo and offers an intimate look at Hansens life, particularly his later years while he dealt with his terminal cancer diagnosis.

Heres a look at the films description:

An extraordinary poker talent sends the young Norwegian Thor Hansen on a life journey as an international poker star in Las Vegas. For 23 years he lives a jet-set life, with hundreds of thousands of dollars to play for daily. He becomes a two-time world champion, and is given the nickname "The Godfather". But in 2012, his life changes dramatically as Thor is diagnosed with incurable cancer. He returns to Norway with his American wife Marcella, and is predicted six months left to live. But a death sentence is just a new challenge for a man who is used to winning, even with lousy cards on his hands.

Hansen, born June 23, 1947, was a two-time World Series of Poker bracelet winner with just shy of $3 million in lifetime earnings dating back to 1987. Not only that, he played in high-stakes cash games, including as a personal recruit of Larry Flynt in the mid-1990s. In 1999, he married Marcella Braswell, who is featured prominently in the documentary. They were together until his passing on December 5, 2018.

PokerNews had the opportunity to chat with Linn Amundsen, one of the directors of the documentary, who opened up about the experience, challenges, and of course the subject himself, Thor Hansen.

When and how did you meet Thor Hansen? What was your relationship?

In Norway poker has actually been forbidden to play, and in a way still is. You can play at home with maximum 10 people and about 100 dollars each, but playing bigger tournaments are not allowed. Except once a year since 2015 there has been the Norwegian championship in Norway. Every year there is also the Norwegian championship in Dublin, because of these restrictions.

In the championship arranged in Oslo in 2015, we were doing a job for the Norwegian blood cancer society. They were selected to get the profit from this arrangement, and we were doing the ideal advertising for them. Since these small films were screened among people interested in poker, we wished to do a poker-related film, and we then needed two actors. One we had already found, but when we searched in the poker society Thor Hansen`s name came up. We were told that he was the Godfather in Norwegian poker and that he also had cancer.

We set up a meeting to discuss his little actor role, and fell in love with him in the first meeting. We then asked if we could make a documentary film about his life, and he responded: Why not?

This is the film we made with Thor for the blood cancer association:

How would you describe Thor Hansen as a person? Likewise, how would you describe his battle with cancer?

Thor was a very charismatic person. He was very friendly and interested in people. He had an adventurous life and had almost never had a normal job. He has won so much money, but also wasted all of it since he was a notorious gambler. We met some dealers when we were filming in Dublin, and asked them some questions about Thor. One person started crying when she started talking about him. So many people loved him because he showed real interest in other people.

He knew their names and knew where they came from. When he sat by the poker table, he talked with people, sang stanzas from old songs, and was always in a good mood. Maybe this was also one of his great skills at the poker table, he got to know people and could easier read them.

I think he was a curious and easy-going soul, who lived one day at a time, and this was maybe an advantage when he got his cancer illness. The doctors in the US gave him sixth months to live. When he got back to Norway, he received more than 300 chemotherapy treatments and lived for six years, playing poker to the end.

What inspired you to make this film?

We got inspired by Thor and the way he lived his life. Not his notorious gambling, but to live life to the fullest and enjoy life as much as possible in any situation. While shooting this film we had other projects going on at the same time, so we didnt have much time to apply for financial support.

"We thought Thor deserved this film, and we also got the impression that he was a bit proud that we were making a film about his life."

Kari, my business partner, co-director, and best friend had also had cancer some years earlier, so we knew a lot about this disease. While filming Thor, she unfortunately got a recurrence of cancer and was actually in the same situation as Thor, since there was no cure for her cancer either. When we had been filming Thor for a year or so, and Kari became sick again, it became more important to complete the film, even though we had to pay the expenses ourselves. We thought Thor deserved this film, and we also got the impression that he was a bit proud that we were making a film about his life.

What has been the reception of the film thus far?

We showed it for the first time in Dublin in 2019, under the Norwegian Poker Championship. About 150 people watched it there, mainly men. Most of them were crying after watching the film, and of course, many people knew Thor. We were there with his wife Marcella, and it was very touching to see all the guys after the screening. If Thor was there in his spirit, he would have been very proud, I think.

What were some of the challenges associated with making this documentary?

The main challenges were that we had other big projects during the three years of filming, so we had to try to plan recordings with him in between those. And we had to do the filming when Thor had the energy. Sometimes we had planned to do some filming, but Thor didnt feel well so we had to postpone our plans. We really wanted to go to Las Vegas with him, but this was not possible because of the other projects we had. Besides that, we also had very little money for the project.

What were some of the highlights for you while making the documentary?

The highlight for us making the film was to get to know Thor and his lovely wife Marcella. She was not into poker at all, but gave him so much love and caring during his disease. Every time he had been to a tournament he was so exhausted, but after being in her care for a few days he had renewed his energy.

It was also very interesting to get an insight in the world of poker. We tried to play a few times, but that was really scary.

Can you give us an update on Marcella? How about Thors friend Steinar?

Steinar, who you see a lot in this film, also died just before Christmas. So that was really sad.

Marcella stayed in Norway after Thor died. She went to some Norwegian classes and her goal is to find a job here. Last summer she went back to the US to catch up with her family, but she had a really tough time, because she lost a young family member to the Covid-19 while she was there. She came back to Oslo a few months ago and is still in great grief because of all her losses the last couple of years.

How did you get noted musician Angelina Jordan to do music?

Kari, my co-owner of Zacapa Film, edited a music video with Angelina Jordan about five years ago. Then we got to know her family. Some years ago, we applied for funding on an idealistic project about bullying together with Angelina and her grandmother, who is also a great artist. Unfortunately, we did not manage to get the financial support and a bit later they moved to the States. I think Angelina liked the song Smile, which was important for her. Her uncle is her manager, and he is interested in poker and also liked our film about Thor.

How can poker fans watch the film?

Poker fans can watch the film on Vimeo here.

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Suspect accused of cloning debit cards, withdrawing thousands from ATMs in New Jersey – FOX 29 News Philadelphia

Posted: at 11:31 am

MOUNT LAUREL, N.J. - Mount Laurel police are advising residents tocheck theirbank statements after neighbors may have had their debit cards cloned and money stolen from their bank accounts, by a man who frequents stores in the area.

Police believe the suspect lives or works nearUnion Mill Road. They say he stole information, then withdrew money from Wawa ATMs in Camden and Burlington counties.

"It is a little scary knowing that somebody is in there, preying on people during these hard times that we have and stealing and taking money," Anthony Duckett said. "Its very upsetting."

The majority of the victims are Mount Laurel residents, according to police. Most of their information was obtained in November 2020.

Public Information Officer Kyle Gardner says half a dozen people filed police reports, but Mount Laurel police worry other neighbors had money stolen without even realizing it.

"There is so much technology out there that obviously can be used for good and bad and in this case, your hard-earned money is being taken by someone who has the technology to do so," Gardner said.

Anyone who may know the identity of this suspect is kindly asked to contact Mount Laurel Police Department at 856-234-8300, the confidential tip line 856-234-1414 Ext. 1599, or email Detective Amaro at lamaro@mountlaurelpd.org.

___

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Star Wars: Why The Republic Used Clones Instead Of Droids – Screen Rant

Posted: at 11:31 am

In the Star Wars prequels, the Republic chose to use clones for their army instead of droids, which is a decision that can be traced to George Lucas.

In the Star Wars prequels, the Grand Army of the Republicwas made up entirely of clones, instead of battle droids, and the Republic had good reasons for their decision in that matter. Although clone troopers were some of the best warriors in the galaxy, a droid army would've been easier to produce and command, without a myriad of financial, logistical, and moral issues that accompanied the controversial process of cloning.

The mere idea of a genetically engineered a clone army went against everything the Republic and the Jedi stood for. Millions of living, sentient beings were intentionally created for one purpose: to kill. And then after their mission was over, they were to die off relatively quickly given their accelerated aging.Droids, on the other hand, displayed no such issues. Devoid of emotions, artificial soldiers could follow commands without question and be sacrificed in great numbers without ethical and moral implications. Additionally, a droid army would've easier to make, maintain, and replace.Everything that would go into making a clone army - time, training, shelter, and so forth - wouldn't have been needed for a droid army.

Related:Star Wars: Why The First Order Didn't Use Clone Troopers

Part of the reason the Republic used clones instead of droids can be traced to George Lucas and his idea of nature versus technology in the prequels. In Star Wars: Episode I - The Phantom Menace, the soulless Trade Federation battle droidscontrastedwith the human and Gungans of Naboo, as well as the planet itself.But it was in the later prequel films the clones became the Republic's defenders. Although they were the heroes, the allusions to the faceless imperial troopers were difficult to ignore. So by allowing the clones to do their dirty work, it was implied the Republic and the Jedi both lost their moral compass and, in turn, contributed to their downfall by succumbing to hubris.

In more practical terms, the Republic had chosen to use the clones because it was convenient. The Clone Army was already ready-to-go when Obi-Wan Kenobi visited Kamino. It was ordered and paid in advance in the name of Republic and had full logistical support; the leaders of the Republic could not abandon such an opportunity, especially with the threat that was facing them. Cloning was expensive, but by using the clone troopers, the Republic could avoid the politically tricky matter of conscription. Since the clones were combat-ready, there was no need for investing time and money into bootcamps or droid-producing factories. Further, after the bloodshed at Naboo, it was hard to imagine Republic citizens being supportive of a droid army.

Unlike the mindless droids, the clones were intelligent soldiers, who were able to think creatively and learn and adapt quickly. Those qualities made them superior to any droid on the battlefield. They were also able to show individuality, as seen in The Clone Wars series. All of these qualities strengthened the bond with their commanders, the Jedi Generals. But little did the Jedi know of the darker side of that close relationship. Their proximity to the Jedi allowed the clones to wipe out their commanders when Order 66was executed. After all, the Republic's use of clones instead of the droids was a part of Darth Sidious grand plan; a Trojan horse that toppled down both the Jedi Order and the Republic. Had the Republic used a droid army instead, Order 66 could have been revealed earlier, during a routine checkup.

When all pros and cons are considered, clones outperformed droids on many levels. There were ethical issues to be considered, but the sudden outbreak of war left the Republic with little choice. With the clone army being readily available, and given their superior qualities, it's easy to understand why both the Republic and the Jedi seized the opportunity. The choice paid off, and it was only at the very end of the war, when Palpatine activated his nefarious plan, that the real role of the clones was revealed. Ironically, their role in erasing the Jedi Order from the Star Wars galaxy is the best testament to the superior military prowess of the clone troopers.

More: How Star Wars: The Clone Wars Set Up Order 66 All Along

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