Daily Archives: December 19, 2020

Digital technology was a lifeline for many educators this year, but it was also a source of frustration, bewilderment, and fatigue.

Videoconference platforms allowed teachers and students to stay in touch even when they couldnt set foot in the same room, but they also presented a host of privacy, logistical, and learning challenges.

Learning management systems and online repositories of course materials supplied teachers with tools for collecting student work and disseminating activities, but they proved daunting to some educators who hadnt used them before.

Wi-Fi hotspots and portable computers kept students and teachers connected from home, but the digital divide became more prominent than ever as longstanding inequities in technology access threatened to widen existing gaps in opportunity and achievement for students of color, students with disabilities, and students in other vulnerable and marginalized groups.

It was a dizzying, dramatic, devastating year that brought education technology to the forefront at an unprecedented scale and transformed the education landscape in ways that may only become clear with years of distance.

To help you make sense of the chaos and better understand how the past nine months will shape the use of technology in K-12 education for years to come, we turned back to the journalism Education Week reporters produced in 2020 and the related survey data from the EdWeek Research Center.

Due to COVID-19, millions of students have been learning from home since March or only attending school buildings part-time for a good portion of the current school year. Teachers have had to use videoconference platforms like Zoom and Microsoft Teams, as well as lower-tech alternatives such as phone calls and emails, to keep in touch with their students. Many teachers prioritized ensuring that their students were doing well emotionally, and that they were able to access instruction even when they couldnt go to school in person.

The nationwide closure of K-12 school buildings this spring, and the ongoing hybrid and remote learning in many districts this fall, has made keeping in touch with all students challenging. Last spring, in particular, schools struggled to reach significant portions of their student population. Those practices have improved, though, and recent EdWeek Research Center data shows the number of teachers interacting with all of their students every day has nearly doubled in recent weeks from the low points of the spring.

Key lessons have been learned about teacher-student interaction that will be relevant when students return to school buildings full time.

Prior to the pandemic, few U.S. schools had robust experience teaching most or all of their students virtually. Online instruction can take many different forms, some of which more closely resemble typical in-person instruction than others. Many online learning experts have urged schools to find ways within their limited resources to minimize live instruction time for their students, and to instead encourage self-directed and project-based learning.

But those massive shifts in instruction arent easy to pull off amid a crisis situation, especially for younger students. Many teachers this fall have found themselves in dual teaching mode, with some students in person and others at home. Teachers have found that juggling act difficult, and some schools have rearranged teaching assignments so that virtual students and in-person students can be assigned to separate groups of teachers.

Proponents of online learning have repeatedly cautioned education observers to avoid drawing neat conclusions about attitudes towards online learning based on how it looked for K-12 schools this year. Remote learning plans constructed during an unprecedented public health crisis will not look the same as efforts that are developed with years of deliberate planning and intensive training for teachers and other school staff.

Still, remote learning drew a wide range of passionate reactions this year, and a few notable trends emerged. Black and Latinx people, and people in districts where fewer than 30 percent of students are white, were more likely to support full-time remote learning in their districts than white people, and people in districts where more than 80 percent of students are white. The same is true for residents of urban areas, suburbs, and towns, who were more likely to support full-time remote instruction than residents in rural areas.

To begin to understand those trends, its worth noting that Black and Latinx people have suffered a disproportionate brunt of the pandemics tally of deaths and hospitalizations, and that rural areas continue to have major gaps in home internet access, which has been essential for students who cant enter school buildings to access instruction.

As the virus affected some areas of the country more severely than others at various points throughout the year, schools weighed the importance of keeping students and staff safe from COVID-19 exposure with the risks that extended building shutdowns would lead to social isolation and learning loss for students, particularly those in vulnerable groups like English language learners and students with disabilities.

Hybrid learning emerged as a somewhat more palatable alternativesmaller groups of students returning to school buildings for two or three days a week, with vulnerable students prioritized for in-person instruction, and remote learning continuing as a full-time option for those who didnt feel comfortable with any in-person contact.

One key question that was rarely asked in classrooms prior to the pandemic: Are we required to have our cameras on?

While students and teachers have been apart, the question of what constitutes class participation from home has come up repeatedly. Some students are reluctant to turn on their cameras while on videoconference sessions because theyre uncomfortable showcasing their surroundings. Some schools are reluctant to require that cameras be turned on for those reasons, while others have said students need to have their cameras on to prevent them from entering videoconference sessions without actively participating.

Hundreds of school districts have been working for years to get one laptop or tablet in the hands of each of their students. For many districts, those efforts accelerated rapidly this year, as the urgency of ensuring every student had equal technology access increased considerably. In the process, schools and the public could no longer ignore or minimize a decades-old problem that lacks an easy solution: Millions of Americans arent adequately connected at home to participate in remote learning without headaches or hiccups. The persistence of that problem, despite significant progress to address it, will remain a formidable challenge in the new year and beyond.

Learning from home is easier for some students and teachers than for others, but its clear from this years experiences that the U.S. education system has a lot of work to do before remote learning can be viewed as a viable option for most students. Teachers reported struggling to keep students engaged during videoconference sessions, dealing with technical snags that posed obstacles to consistent instruction, and slogging to keep up with an ever-growing mountain of phone calls and other interactions to ensure that students are staying on track.

With more widespread use of technology, especially outside of school buildings and away from school networks, came more vulnerabilities to cyberattacks and potential for violating privacy rules and norms. The Federal Bureau of Investigation warned that K-12 schools were among the most common targets of hackers, and a wave of school districts have experienced disruptive cybersecurity threats in the last few months alone. The term Zoombombing entered the lexicon, referring to incidents in which hackers disrupted virtual classrooms and school board meetings with profanities, slurs, and obscene imagery. The actions necessary to keep students safe were markedly different this year, and the threats came from a diverse array of sources.

Ed-tech experts are predicting that the increasing use of technology in K-12 education fueled those cyberattacks more than ever during COVID-19, but is likely to continue to be a big problem for schools even after the pandemic.

Link:

Education Technology in 2020: 8 Takeaways From a Chaotic Year - Education Week

While animal empathy is still controversial considering our various lifestyle choices some people still know how to make a difference in their lives. One such person is Alpana Bhartia, an animal lover who is teaching people to care for animals by empathising with them.

This week on SocialStory, we saw a slew of stories of people and organisations trying to make it better for underserved and disadvantaged communities with their inclusive platforms, community development initiatives, and pandemic aid.

Here are the top Social Stories of the week:

Alpana Bhartia, Founder Trustee, People for Animals

An honourable animal welfare officer, Alpana Bhartia has been working in the field of animal welfare and conservation for the past 25 years. She is a constituted member of the Institutional Ethics Committee of the National Centre for Biological Studies (NCBS). In fact, she has been nominated by the Government of India to the committee for Control and Supervision of Experiments on Animals.

Being empathetic towards animals is something Alpana had learnt right from her childhood. Born in Kolkata in a traditional Rajasthani family, she had grown to become very fond of pets and animals as her father always kept dogs.

Vineet Saraiwala has built India's first-ever hiring platform exclusively for Persons with Disabilities

Vineet Saraiwala, a business executive with The Future Group, built Atypical Advantage Indias first-ever talent platform exclusively for PwDs. The IIM Bengaluru graduate discovered a gap when he was looking for a voice-over artist for a retail space designed for PwDs.

Atypical Advantages website already lists 16 categories of skills, including photographers, physiotherapists, graphic designers, models, dancers, singers, painters, and sign language interpreters.

The platform, which has over 200 people listed on it, encompasses a profile page of the individual with a short bio, a list of their talents, contact details, and the nature of their disability.

Who doesnt dread a Monday morning! Through our Monday Motivation series, SocialStory strives to remove the dread attached to Mondays by bringing you stories of inspiration and positivity, and arm you with the right attitude for the week ahead.

Despite being the year of the pandemic, 2020 saw several individuals from an IAS officer educating children in Jharkhand to an IRS officer going all out to help migrant workers during the lockdown going above and beyond the call of duty to help others.

Some of the volunteers who are a part of Project StepOne in Delhi

The outbreak of the COVID-19 pandemic saw an increased need for remote healthcare with hospitals becoming increasingly inaccessible. There was an urgent need to both contain the spread of the virus and assist people in need of physical and psychological care.

To fill this gap,a group of volunteers from a wide range of sectors medical, technical, marketing, and operations came together to form StepOne, a not-for-profit platform in June 2020.Their mission was to blend technology and human resources to provide healthcare access to those who most needed it.

By the first week of December 2020, the StepOne team had completed nine lakh teleconsultations, prevented five lakh contacts spreading the virus, and, in turn, impacted the lives of five million citizens.

Cranberry Analytics founder (L-R) Amit Deshmukh, Shishir Thakur and Onkar Gauridhar

Started in 2010 by Shishir Thakur, Amit Deshmukh, and Onkar Gauridhar, Pune-based Cranberry Analytics is a technology-enabled analytics startup that works in the area of water measurement.

It works with water utility companies and uses both on-ground and online tech solutions to map water use and water efficiency across its distribution and consumption cycle. Its primary focus is on getting water utilities to reduce cash burn and eventually turn cash-positive.

Read more from the original source:

From caring for wildlife to using technology for water distribution, here are the top Social Stories for the w - YourStory

Technology stocks have historically led market rallies, and this year has been no exception. The Technology Select Sector SPDR Fund (NYSE: XLK) has advanced about 40% year-to-date, with stocks levered to remote work and study makingstrong upward moves.

As an unusual year draws to a close, here are12 key technologiescompiled by Lux Researchthat will likely be in the spotlight in 2021.

Autonomous Vehicles: Increasing levels of vehicle automation, especially Level 4 and 5 autonomous vehicles, will eventually remove the need for a driver in consumer and commercial vehicles, Lux Research said.

Investors can tap into emerging opportunities in areas such as sensors and connectivity for autonomous vehicles, the report said.

Some beneficiaries could be lidar solutionproviders such as Veoneer Inc (NYSE: VNE), ON Semiconductor Corp (NASDAQ: ON), NXP Semiconductors NV (NASDAQ: NXPI), Autoliv Inc. (NYSE: ALV), Texas Instruments Incorporated (NASDAQ: TXN) and NVIDIA Corporation (NASDAQ: NVDA).

Natural Language Processing: This is the branch of artificial intelligencethat helps computers understand, interpret and manipulate human language.Patents related to this technology, which powers devices such as voice assistants, machine translationand chatbots, have increased at a compounded annual growth rate of 44% annually over the last five years, Lux Research said.

Some of the key players in the segment include Apple Inc (NASDAQ: AAPL), Alphabet Inc(NASDAQ: GOOGL), Amazon.com, Inc.'s (NASDAQ: AMZN) AWS, Hewlett Packard Enterprise Co (NYSE: HPE), Intel Corporation (NASDAQ: INTC), IBM(NYSE: IBM), Microsoft Corporation (NASDAQ: MSFT), Adobe Inc (NASDAQ: ADBE) and 3M Co (NYSE: MMM).

Plastic Recycling: This comprises of innovations that convert plastic waste into a variety of valuable products, serving the dual purpose of enabling a circular economy and avoiding pollution, Lux Research said.

In the last decade, 155 star-ups addressing plastic waste have been founded, the report said.

Stocks to play the trend include Loop Industries Inc (NASDAQ: LOOP).

AI-Enabled Sensors: AI techniques such as machine learning have provided methods to analyze and derive insight from sensor data, unlocking new sensor capabilities and applications, Lux Research said. Thisis being used in computer vision for analyzing image sensor data.

The firm also sees other sensor types such as mechanical, acoustic and even thermal sensors as being impacted by AI tools.

Bioinformatics: This is the application of computer technology to the understanding and effective use of biological and clinical data. Key applications of this technology include diagnostics, discovery, personalization, quality and optimization, risk assessment andsafety and traceability.

Roche Holdings AG Basel ADR Common Stock (OTC: RHHBY), Bio-Rad Laboratories, Inc. Class A Common Stock (NYSE: BIO) and Irhythm Technologies Inc (NASDAQ: IRTC) are among the bioinformatics plays.

Green Hydrogen: This technology is focused on producing clean hydrogen for energy, mobility and industrial uses.

Plug Power Inc (NASDAQ: PLUG), Bloom Energy Corp (NYSE: BE) and TM Power plc (OTC: ITMPF) are green hydrogen stocks to capitalize on this emerging trend.

Shared Mobility: Shared mobility is an innovative transportation strategy that allowsusers to gain short-term access to transportation modes on an as-needed basis.

The includes various forms of carsharing, bikesharing, ridesharingand on-demand ride services.

Shared mobility, according to Lux Research, is poised to disrupt the multibillion-dollar auto industry.

"Self-driving cars, zero-emission vehicles, connectivity, and innovative materials are defining the future of mobility," the report said.

Ride-hailing companies such as Uber Technologies Inc (NYSE: UBER), and LYFT Inc (NASDAQ: LYFT), robotaxi services such as Google's Waymo, Amazon's Zoox, Baidu Inc's (NASDAQ: BIDU) Apollo and electric vehiclestocks are avenues of staying invested in this promising arena.

Related Link: How Technology, COVID-19 Are Changing Financial Planning

Alternate Proteins: Demand for alternative proteins have been on the rise, supported by factors such as consumer preferencesand supply and environmental concerns, according to Lux Research. Alternative proteins are sourced from plants, insects, fungi or through tissue culture to replace conventional animal-based protein. This trend should work in favor of plant meat companies such as Beyond Meat Inc (NASDAQ: BYND).

3D Printing: 3D printing is an additive process in which aan object is created by laying down successive layers of material.

It is used in industries such as automotive, aviation, construction, consumer productsand health care.

Some of the listed 3D companies are HP Inc (NYSE: HPQ), Proto Labs Inc (NYSE: PRLB), Materialise NV (NASDAQ: MTLS), Organovo Holdings Inc (NASDAQ: ONVO), Stratasys Ltd (NASDAQ: SSYS) and 3D Systems Corporation (NYSE: DDD).

Materials Informatics: It is a field of study that applies the principles of informatics to material science and engineering to better understand the use, selection, developmentand discovery of materials.

Precision Agriculture: It is an approach to farm management that uses information technology to ensure that crops and soil receive exactly what they need for optimum health and productivity with an objective of ensuring profitability, sustainability and protection of the environment.

Synthetic Biology: Synthetic Biology combines engineering principles and molecular biology techniques to produce novel biological solutions.

This multidisciplinary field brings together engineers and biologists, who are developing these solutions for useful purposes, across numerous areas including diagnostics, therapeutics, manufacturing and agriculture.

Twist Bioscience Corp (NASDAQ: TWST), Thermo Fisher Scientific Inc. (NYSE: TMO), Bristol-Myers Squibb Co (NYSE: BMY), Amyris Inc (NASDAQ: AMRS) and Codexis, Inc. (NASDAQ: CDXS) are among the companies that are working on this technology.

Related Link: Tech Industry Vets At engin sciences Use AI To Fix Cannabis's Big Problem

2020 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.

Excerpt from:

12 Emerging Technologies To Watch In 2021 - Benzinga

LONDON--(BUSINESS WIRE)--The MOCVD market is poised to grow by USD 84.93 mn during 2020-2024, progressing at a CAGR of over 5% during the forecast period.

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The report on the MOCVD market provides a holistic update, market size and forecast, trends, growth drivers, and challenges, as well as vendor analysis.

The report offers an up-to-date analysis regarding the current global market scenario and the overall market environment. The market is driven by an increasing focus on renewable energy.

The MOCVD market analysis includes end-user segment and geography landscape. This study identifies the entrance of multiple suppliers of SiC wafers as one of the prime reasons driving the MOCVD market growth during the next few years.

This report presents a detailed picture of the market by the way of study, synthesis, and summation of data from multiple sources by an analysis of key parameters.

The MOCVD market covers the following areas:

MOCVD Market SizingMOCVD Market ForecastMOCVD Market Analysis

Companies Mentioned

Related Reports on Information Technology Include:

Key Topics Covered:

Executive Summary

Market Landscape

Market Sizing

Five Forces Analysis

Market Segmentation by End-user

Customer landscape

Geographic Landscape

Vendor Landscape

Vendor Analysis

Appendix

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The MOCVD Market 2020-2024- Featuring Advanced Micro-Fabrication Equipment Inc., Agnitron Technology Inc., AIXTRON AG, Among Others to Contribute to...

NEW YORK, Dec. 18, 2020 /PRNewswire/ --Capt. Franz Almeida has a practiced eagle's eye, honed over thousands of flight hours as a pilot. Junaid Mian, RPh, understands the challenges inherent to maintaining human health through the lens of work as a pharmacist. Both followed unique paths, which led them to angel investing. The two met at the NY chapter of the Harvard Business School.

Together they identified a yawning gap between space technology and biotechparticularly longevityverticals. They recognized that the world's economy is in the throes of change so radical that future generations will see the 21st century as a clear delineation marking a decidedly Earthbound humanity split from humanity that can freely live in and explore space.

The space economy explosion is happening, and there is no better time to invest than as early on as possible during that explosion. The latest estimates of the global space economy are well over $400 billion, and if growth continues to accelerate, many analyses point to a $1 trillion space economy just around the corner. The human longevity market is nearly as massive: A Merrill Lynch analysis revealed that the sector generates over $110 billion annually now and is growing to over $600 billion by 2025.

Without massive and ongoing investment and progress across both space technology and human longevity verticals, we will never be able to truly unlock the potential that our Solar System, and our galaxy, holds.

"A big part of why progress against aging used to be so slow was that so few experts on aging had an engineer's way of thinking. The convergence of those communities is making all the difference."

Aubrey de Grey, VP of New Technology Discovery at AgeX Therapeutics, Inc and Chief Science Officer of the SENS Research Foundation and Human Longevity advisor at SP8CEVC

And that's where Junaid Mian, RPh, and Capt. Franz Almeida comes in. The pair's varied perspectives have been a decisive match when it comes to examining the potential in merging investments across the space tech and human longevity verticals. Almeida and Mian are launching a new Rolling Fund in partnership with AngelList, with an exacting focus on solving the problem that is the future of humankind.

Under the umbrella of SP8CEVC, LPs will be able to gain exposure to deals to empower growing ventures in space technology and human longevity. Why these two rather specific categories? Simple: Moving to an economy based on the resources of our entire Solar System enables a much more substantial timeline for humanity's existence, and biotechnology work in longevity enables people to live and work in space.

The SP8CEVC partners who initially started with a traditional fund structure have chosen to use AngelList's rolling fund Reg 506(c) model to open up investment possibilities in these most critical verticals. As a series of quarterly pooled investment funds, SP8CEVC will give investors access to their deal flow quarterly on a subscription basis.

This new structure accelerates the pace of investing and, as a benefit, also helps promote innovation in those businesses.

The SP8CEVC team launched yesterday at TechCrunch Sessions: SPACE 2020. Investors and LPs interested in setting the pace for future advancement can have access to SP8CEVC's deal flow before anyone else here.

Media Contact:Franz Almeida917-287-5674 [emailprotected]

SOURCE SP8CEVC

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Introducing SP8CEVC: The World's First Space Technology and Human Longevity Focused Rolling Fund in Partnership with AngelList - PRNewswire

Westport, CT, Dec. 18, 2020 (GLOBE NEWSWIRE) -- BioSig Technologies, Inc. (NASDAQ: BSGM) (BioSig or the Company), a medical technology company commercializing a proprietary biomedical signal processing platform designed to improve signal fidelity and uncover the full range of ECG and intra-cardiac signals, today announced that the Company and its NeuroClear Technologies division signed a new research agreement with the University of Minnesota.

Under the terms of the agreement, the Company intends to launch a program to develop novel therapies to treat sympathetic nervous system disease. Due to launch in Q4 2020, the program studies are expected to form a foundation for developing a new platform technology to address disorders of the autonomic nervous system. NeuroClear intends to develop new intellectual properties and products, including new hardware, software, and algorithmic solutions, with the support of a tier 1 US-based manufacturing partner and take it through FDA approval, manufacturing, and commercialization. The R&D program will be run under the leadership of Richard W. Bianco, Ph.D., Professor, Director of Experimental Surgical Services (ESS), Department of Surgery in the University of Minnesota Medical School, John W. Osborn, Ph.D., Professor, Department of Surgery and Director of the Minnesota Consortium for Autonomic Neuromodulation (MCAN) in the University of Minnesota Medical School and Barry Keenan, Ph.D., Vice President of Engineering at NeuroClear.

We are very pleased to commence a new research and development program with the accomplished team at the University of Minnesota. Our mission is to lead through innovation in bioelectronic medicine, and we are most impressed with the cutting-edge research work led by John and his colleagues. Our team made tremendous progress in the past twelve months, having identified several lucrative opportunities, onboarded a leading manufacturing partner, and developed a scientific proposal to drive this program forward. We are thrilled to begin this new chapter and look forward to reporting on our progress, commented Kenneth L Londoner, Chairman, and CEO of BioSig Technologies, Inc.

I am extremely excited about this strong collaboration between the University of Minnesota and NeuroClear Technologies. This agreement combines the rich expertise in autonomic neuromodulation, the 40-year track recorded of ESS in device development at the University of Minnesota, with NeuroClears mission to develop technology for recording and processing of biological signals specifically for treating the diseases of the autonomic nervous system. This aligns perfectly with the mission of MCAN. said John W. Osborn, Ph.D.

University of Minnesota is at the forefront of autonomic neuromodulation research. We believe that with their expertise, resources and collaboration, we can accelerate product development of new novel bioelectronic medicine devices, commented Barry Keenan, Ph.D., Vice President of Engineering of BioSig Technologies, Inc.

The Company previously reported that it appointed John W. Osborn, Ph.D. as a Consultant on autonomic neuromodulation and raised $3.7 million in an initial seed round in August 2019.

About NeuroClear TechnologiesFounded in November 2018, NeuroClear Technologies aims to address some of the biggest challenges in bioelectronic medicine, including, but not limited to, targeted nerve stimulation and a closed feedback loop system. NeuroClear intends to build upon the core competencies in recording and analyzing intracardiac, surface ECG and neuronal signals, which have been already validated by BioSig, and develop a dedicated product line to address and advance current therapies within several markets, such as cognitive disorders and nephrology.

About BioSig TechnologiesBioSig Technologies is a medical technology company commercializing a proprietary biomedical signal processing platform designed toimprove signal fidelity and uncover the full range of ECG and intra-cardiac signals(www.biosig.com).

The Companys first product,PURE EP (tm) System,is a computerized system intended for acquiring, digitizing, amplifying, filtering, measuring and calculating, displaying, recording and storing of electrocardiographic and intracardiac signals for patients undergoing electrophysiology (EP) procedures in an EP laboratory.

Forward-looking Statements This press release contains forward-looking statements. Such statements may be preceded by the words intends, may, will, plans, expects, anticipates, projects, predicts, estimates, aims, believes, hopes, potential or similar words. Forward-looking statements are not guarantees of future performance, are based on certain assumptions and are subject to various known and unknown risks and uncertainties, many of which are beyond the Companys control, and cannot be predicted or quantified and consequently, actual results may differ materially from those expressed or implied by such forward-looking statements. Such risks and uncertainties include, without limitation, risks and uncertainties associated with (i) the geographic, social and economic impact of COVID-19 on our ability to conduct our business and raise capital in the future when needed, (ii) our inability to manufacture our products and product candidates on a commercial scale on our own, or in collaboration with third parties; (iii) difficulties in obtaining financing on commercially reasonable terms; (iv) changes in the size and nature of our competition; (v) loss of one or more key executives or scientists; and (vi) difficulties in securing regulatory approval to market our products and product candidates. More detailed information about the Company and the risk factors that may affect the realization of forward-looking statements is set forth in the Companys filings with the Securities and Exchange Commission (SEC), including the Companys Annual Report on Form 10-K and its Quarterly Reports on Form 10-Q. Investors and security holders are urged to read these documents free of charge on the SECs website at http://www.sec.gov. The Company assumes no obligation to publicly update or revise its forward-looking statements as a result of new information, future events or otherwise.

Originally posted here:

BioSig's Division NeuroClear Technologies Signs a Research Agreement with the University of Minnesota - GlobeNewswire

If youre producing a lot of waste, there is something not functioning efficiently inside your ... [+] organization" says Nate Morris, Chairman and CEO of Rubicon.

As more people and companies pursue a zero-waste future looking to reduce what they dispose of and maximize the reuse of materials and expectations around ESG reporting grow, a new industry has emerged that uses software and other technology to advance these goals.

One leader in the growing zero-waste field is Rubicon, founded by Nate Morris, who serves as Chairman and CEO. The Lexington, Kentucky and New York City-based company was born from his combined interests in public policy, the environment, and the application of technology solutions to solve complex problems. Now, he and the rest of the Rubicon team enables businesses and governments to reduce their waste and manage their recycling while also finding ways to help their customers save money and meet sustainability goals.

Waste is a design flaw, Morris says. If youre producing a lot of waste, there is something not functioning efficiently inside your organization. It is really an indicator of a sophisticated business if you have a very lean and efficient recycling operation.

As a Certified B Corporation, Rubicon also amplifies its mission to end waste by diverting waste away from landfills and protecting the planets future. To learn how Rubicon uses technology to shrink clients trash piles and enhance their ESG (environmental, social, and governance) credentials, I talked with Morris as part of my research onpurpose-driven business.

Im curious about the story behind Rubicon why and how did you start the business?

Nate Morris, Chairman and CEO of Rubicon

Nate Morris:Rubicon really represents a passion that Ive had since high school around public policy and the intersection of government and business, and using free market solutions to solve the biggest and longest-standing challenges our world faces. And waste is one of the oldest of those. It goes back to the beginning of civilization, and is one of those issues that we dont want to think about we just want to keep it out of sight and out of mind.

Often its thought that making money and doing something good for the environment are mutually exclusive propositions. But I believe we can do both, and that the greatest catalyst for environmental change can come through business. Where government has sometimes struggled with solutions to these kinds of complicated problems, innovative businesses have stepped up and found ways to tackle them. That is really what drove me to start looking at a lot of these kinds of broader, human issues and what would ultimately lead me to waste.

Waste tells a story about what we are leaving behind a legacy of sorts and there is a prime opportunity for my generation of entrepreneurs to reimagine this category. We have an industry thats been built almost entirely around landfills and burying garbage in the ground, and I felt strongly that that needed to change.

How does Rubicon use technology to make waste reduction more efficient and feasible?

Waste is known as the toughest industry in the world, and one with very little transparency into its actual functions and operations.

Very few people, if any, ever ask questions about their waste. What's going on with my waste bill? How much is my recycling? How much am I paying each month? Its sort of out of sight, out of mind. But technology allows us to leverage the ability to be transparent and to actually get real-time information about whats happening with our waste and recycling.

Its also an industry in which businesses are handed down through the generations, which makes it extremely difficult to break in as a newcomer. Now those relationships from prior generations are being upset by sophisticated technology, the application of data and analytics, software products, and a vision for how the industry is going to evolve and ultimately influence the direction that the environmental movement takes in the future.

Rubicon is a completely digital company, its a software business. Our business model incentivizes other means of disposal something other than burying trash on the ground. We dont own trucks. We dont own landfills. So our incentives are radically different compared to the way the industry has operated historically.

Think about it: If you own the truck, you have to run it to make your profit. So that brings with it a risk that the account is overserviced, meaning that an account that should be picked up five times a week may get picked up seven times a week. We are using our software to analyze the millions of locations we have in our database and adjust the level of service accordingly. Refinements like these can generate six figure, maybe even seven-figure savings right out of the gate, depending on the business. It also results in less wear and tear on the vehicles and the roads themselves and, finally, less drive time, so theres an environmental benefit in that you get tremendous carbon savings, too.

The data doesnt lie, and the data that we have around the country gives us a great indication of what the correct level of service should be, and our mapping capabilities show us the most efficient route. Our CTO tells a great story that in the old days, prior to Rubicon, a collection route could be thrown off for the entire day if the driver preferred Taco Bell over Kentucky Fried Chicken for their lunch stop.

But now we are able to have a more robust industry that is fairer, more open, and that supports small business growth and empowers new entrepreneurs. Were also very excited to see the next generation of entrepreneurs that have recently joined the space and brought diversity to it. There are new haulers that are minority-owned, veteran-owned, and female-owned in our network and they are making it look more like a true reflection of todays America.

Obviously waste is a big issue in the E dimension. But, regarding your ESG reporting business, what about the S and G dimensions for example, helping companies examine gender dynamics and racial composition of their workforce and governance issues and things like that?

ESG reporting has become a mainstay, and thats because its what the free market demands. Were listening to the market, and what were hearing leads me to believe that there is no greater force for environmental change than business itself. The key driver today is companies saying: Ive got to partner with Rubicon because of ESG reporting requirements. And if I dont get Rubicon, Im not going to get the information that I need to be able to report accurately. They need a credible third party validating those metrics and benchmarks, looking at how theyre doing better year over year related to waste.

I think its accurate to say that waste is a design flaw. If youre producing a lot of waste, there is something not functioning efficiently inside your organization. It is really an indicator of a sophisticated business if you have a very lean, efficient waste and recycling operation. Our software uncovers opportunities for more diversion, which helps to drive up revenue.

We believe the future of Rubicon is going to be centered around what used to be a nice-to-have reporting around recycling and diversion becoming a must-have. A whole generation of consumers are now making purchasing decisions based upon the environmental footprint of the companies with which they spend their money. They look at what youre doing to offset externalities and make sure that you're being responsible with the materials you have.

What the customer and what households are looking for today is sophistication around material. They want to know how to repurpose that material and how to thrive in the 21st century business climate. Customers are voting with their wallet today and are using products to do so they are aligning their dollars with their values.

Thats part of why we became a B Corp. Its just the way we run our business. This is not a moniker that we put up or a nice accreditation. B Corp Certification has informed a lot of our decisions about how weve run and grown our business.

Can you share some examples of companies you started working with and how it has helped them?

One of the businesses that really helped build Rubicon was Papa Johns Pizza. We went to Papa Johns because it was right in our backyard in Kentucky. I remember walking into the meeting and saying to an executive from the company, You know, Ive started this waste company. And he said, Thats great. And you know, I have no idea what were doing with our waste.

So thats often the first conversation that you have with senior executives from a lot of companies. Theyre focused on selling, whether its pizzas or groceries or whatever their product or service might be. Theyre not usually focused on what theyre doing with their waste.

Weve also seen important gains in reverse logistics. With another client, a national variety store chain, we use a robust reverse logistics program where were able to backhaul tons and tons of cardboard. When the trucks drop a load, rather than the trucks going back empty, we load them with cardboard and send that to be recycled. Thats one example of how re-engineering the supply chain can create tremendous revenue and tremendous diversion from landfill. Beforehand that cardboard was just going to the landfill and being thrown away.

We have also partnered with grocery chain Wegmans on their zero-waste journey and made progress toward the circular economy by giving a second life to materials used in the ordinary course of business. Food waste in particular is a massive problem. The U.S. Department of Agriculture (USDA) estimates that 30-40% of the food supply is wasted annually. Its not surprising, then, that committing to zero-waste targets in a grocery setting is a huge challenge that requires elaborate systems thinking revisiting supply chains, establishing sustainable purchasing policies, accurately forecasting demand to minimize spoilage, and managing waste generated in operations. Our program with Wegmans aims to cut food waste in half by 2030.

Throughout our partnership, we have also worked with Wegmans to identify ways of repurposing, refurbishing, and recycling a variety of materials, including non-food products. For instance, weve recycled thousands of pounds of granite countertop, and found a second use for seafood containers and bakery racks. We also developed a program to recycle kitchen oil and grease, and to convert meat products into biofuels. Each solution brings Wegmans closer to their zero-waste goal.

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Waste Is A Design Flaw: Rubicon Taps Technology To Help Businesses And Governments Save Money And Go Zero-Waste - Forbes

DUBLIN, Dec. 18, 2020 /PRNewswire/ -- The "STING Pathway Targeting Therapeutics and Technologies Market, 2020-2030" report has been added to ResearchAndMarkets.com's offering.

The "STING Pathway Targeting Therapeutics and Technologies" report features an extensive study of the current market landscape and future potential of these therapeutics and affiliated technologies, over the next decade. This study focuses specifically on small molecule STING modulators. The report features an in-depth analysis, highlighting the diverse capabilities of stakeholders engaged in this domain.

In recent years, promising insights from research on the cytosolic DNA sensing (cGAS -STING) pathway has caused a lot of enthusiasm within medical science community. Basically, the STING pathway offers an alternative approach to harnessing the immune system, in order to pharmacologically treat a number of clinical conditions, including oncological and autoimmune disorders. The aforementioned therapeutic benefits can be achieved using modulators of the STING/cGAS-pathway. Over the years, a number of such modulators, capable of either activating or downregulating the STING pathway, have been developed. More than 50 experimental interventions based on this relatively novel concept are currently being developed for the treatment of oncological, autoimmune and inflammatory disorders.

The popularity of STING pathway modulation and growing interest of drug developers in this upcoming field of therapeutics is evident in the rising volume of affiliated scientific literature (1,000+ related articles on NCBI's PubMed portal since 2015). Moreover, capital investments worth over USD 2.6 billion have been made by various private and public sector investors to fund product development activity. In addition, there have been multiple, high value technology licensing deals in this domain, since 2015.

As a result, there has been a considerable rise in number of companies taking initiatives in this field, over the past 4-5 years alone. Interestingly, several big pharma players are also actively evaluating multiple STING agonists/antagonists. It is also worth noting that molecular research into the pathogenesis of the novel SARS-CoV-2 viral strain suggests that COVID-19 may be a STING-related disorder, characterized by delayed over-secretion of IFN-?.

STING, in humans, is mostly expressed in lung alveolar epithelial cells, endothelial cells, and spleen cells, which are considered crucial for COVID-19 pathogenesis. Therefore, rapid assessments of STING polymorphisms may actually be useful in identifying individuals who are at high risks of contracting a severe form of this infection. Further, a better understanding of the underlying mechanisms associated with the novel coronavirus induced STING-pathway over-activation, may enable the development of potential therapeutic candidates against COVID-19.

Currently, there are no approved STING pathway-targeting drugs/therapy products in the market. However, some promising leads are anticipated to be launched over the coming decade, following which the market is projected to grow at a substantial pace.

One of the key objectives of the report was to estimate the existing market size and identify potential future growth opportunities for novel technologies designed for the development of STING pathway modulators. Based on the likely licensing deal structures and agreements that are expected to be signed in the foreseen future, we have provided an informed estimate on the evolution of the market over the period 2020-2030.

Key Topics Covered:

1. PREFACE1.1. Scope of the Report1.2. Research Methodology1.3. Key Questions Answered1.4. Chapter Outlines

2. EXECUTIVE SUMMARY

3. INTRODUCTION3.1. Stimulator of Interferon Genes (STING) Pathway 3.2. STING Signaling 3.3. STING Pathway Modulators3.4. Key Variants of STING3.5. Non-immunological Functions of the STING Pathway3.6. Concluding Remarks

4. STING PATHWAY TARGETING THERAPEUTICS: CURRENT MARKET LANDSCAPE4.1. Chapter Overview4.2. STING Pathway Targeting Therapeutics: Development Pipeline4.3. STING Pathway Targeting Therapeutics: Developer Landscape4.4. STING Pathway Targeting Therapeutics: List of Clinical Trials

5. STING PATHWAY TARGETING TECHNOLOGIES: CURRENT MARKET LANDSCAPE5.1. Chapter Overview5.2. STING Pathway Targeting Technologies: List of Technology Developers

6. COMPANY PROFILES6.1. Chapter Overview6.2 STING Agonist Developers6.2.1. Aduro Biotech6.2.1.1. Company Overview6.2.1.2. Financial Information6.2.1.3. Product Description: ADU-S100 (MIW815)6.2.1.4. Recent Developments and Future Outlook6.2.2. Bristol-Myers Squibb6.2.3. Eisai6.2.4 GlaxoSmithKline6.2.5. ImmuneSensor Therapeutics6.2.6. Merck6.2.7. Noxopharm6.2.8. Spring Bank Pharmaceuticals6.2.9. Synlogic6.3. STING Antagonist Developers6.3.1 Avammune Therapeutics6.3.2. Curadev6.3.3 ImmuneSensor Therapeutics6.3.4. Nimbus Therapeutics6.3.5. Sirenas6.3.6. Spring Bank Pharmaceuticals6.3.7. STINGINN6.3.8. STipe Therapeutics

7. ACADEMIC GRANT ANALYSIS7.1. Chapter Overview7.2. Scope and Methodology7.3. STING Pathway Targeting Therapeutics: List of Academic Grants7.4. Grant Attractiveness Analysis

8. STING RELATED INITIATIVES OF BIG PHARMACEUTICALS PLAYERS8.1. Chapter Overview8.2. Scope and Methodology8.3. Initiatives Undertaken by Big Pharma Players8.4. Benchmarking Big Pharma Players

9. START-UP HEALTH INDEXING9.1. Chapter Overview9.2. Scope and Methodology9.3. Benchmarking of Start-ups

10. PUBLICATION ANALYSIS10.1. Chapter Overview10.2. Scope and Methodology10.3. STING Pathway Targeting Therapeutics: Recent Publications

11. PARTNERSHIPS AND COLLABORATIONS11.1. Chapter Overview11.2. Partnership Models11.3. STING Pathway Targeting Therapeutics: Recent Partnerships

12. FUNDING AND INVESTMENT ANALYSIS12.1. Chapter Overview12.2. Types of Funding12.3. STING Pathway Targeting Therapeutics: Recent Funding Instances12.4. Concluding Remarks

13. MARKET SIZING AND OPPORTUNITY ANALYSIS13.1. Chapter Overview13.2. Key Assumptions and Forecast Methodology

14. EXECUTIVE INSIGHTS

15. CONCLUDING REMARKS15.1. Chapter Overview15.2. Key Takeaways

16. APPENDIX 1: TABULATED DATA

For more information about this report visit https://www.researchandmarkets.com/r/by50j8

Research and Markets also offers Custom Research services providing focused, comprehensive and tailored research.

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Global STING Pathway Targeting Therapeutics and Technologies Market, 2020-2030 - Promising Leads are Anticipated to be Launched Over the Coming Decade...

The University of California has selected 10 finalists for its 2021 Startup Innovation Challenge, held in partnership with Extreme Tech Challenge (XTC), the worlds largest tech-for-good startup competition. The chosen finalists are comprised of companies with game-changing ideas for fighting climate change, feeding the world, curing diseases and saving the day with robots that can be airdropped into disaster zones.

The finalists will pitch their startups to investors at the Global Corporate Venturing Digital Forum in late January as they compete to take home one of two $50,000 prizes. Finalists will also receive pro bono legal services, be mentored by venture capital judges and have a chance to advance as finalists in XTCs regional startup competition. All startups that applied to the competition are still in the running for XTC.

The finalists are divided into two tracks: A growth-stage track for startups that already have Series A funding or proof points of product-market fit; and an early-stage track for startups that have not yet raised Series A funding. One winner will be selected from each track to receive a $50,000 prize.

The University of California Office of the President launched the annual competition to help UC-affiliated startups build funding and strategic partnership relationships with a global ecosystem of corporations and investors that can carry their companies far into the future, said Victoria Slivkoff, UCs global head of Innovation and Entrepreneurship.

The tenacity, ingenuity and the entrepreneurial spirit of UC founders have never been more inspiring than in these unprecedented times, Slivkoff said.

As these 10 finalists demonstrate, UC startups are making an impact in so many sectors of the economy. We want to see these innovative solutions reach the marketplace to help build a sustainable, equitable, inclusive, healthy and prosperous world.

Auctus Surgical: Treating pediatric scoliosis with less invasive methodsCo-founder: Dr. Mohammad Diab, UC San Francisco professor and vice chair of the Department of Orthopedic Surgery and the Department of Pediatrics at UCSF.

Auctus Surgical is developing a less-invasive spinal implant system known as a vertebral body tethering system (VBT) to correct pediatric scoliosis. The system incorporates a dynamic magnetic technology permitting a childs spine to be non-surgically adjusted, eliminating the need for traumatic fusion surgery.

Fixing CO2: Transforming air emissions into renewable fuelsCo-founder and CEO: UC San Diego alumnus Dr. Alma Zhanaidarova

What started as a project to figure out how to supply renewable energy on Mars (where the atmosphere is 95 percent carbon dioxide) is now squarely focused on solving global climate change here on Earth. The Fixing CO2 team is developing a reactor that uses solar and wind energy to convert carbon dioxide emissions into fuels and chemicals. Instead of making fuels from oil or any other fossil sources, we can make them essentially from air, Fixing CO2 co-founder Eldar Akhmetgaliyev told dot.LA.

KovaDx: Bridging health disparities faced by people with sickle cell diseaseFounder and CEO: UC Berkeley bioengineer and physician Dr. Yaw Ofosu Ansong, Jnr.

KovaDx aims to improve the lives of patients with sickle cell disease by making it quicker, cheaper and easier to diagnose and monitor hemolytic anemias. The company has developed a portable, on-demand, point-of-care diagnostic solution that does not need skilled personnel to administer, making it suitable for use in sub-Saharan Africa and other medically underserved regions. Dr. Ansong, a carrier of sickle cell who has lost family members to the disease, is driven by the hope of improving the quality of life for patients.

Takachar: Turning trash into cash (and helping the planet)Co-founder, President and CTO: Lawrence Berkeley National Laboratory, Cyclotron Road fellow Dr. Kevin Kung

Agricultural and forest waste, known as biomass, can be made into marketable products, like fuel and fertilizer. Yet biomass is too bulky for easy transport to processing sites, so it is usually just burned on site adding to air pollution and climate change. Takachar has an economically viable solution to this problem: the development of small-scale, low-cost portable reactors that use a thermochemical treatment to turn waste biomass into valuable products.

Xiretsa: A new weapon in the fight against superbugsCo-founder: UC Santa Barbara alumnus Patrick Dietzen

Xiretsa is developing a new class of antibiotics that can treat infections unresponsive to current antibiotics. The need is urgent: 700,000 people die each year from antibiotic resistance, and as the problem grows, it threatens to make organ transplants, cancer treatments and even routine surgeries risky. Xiretsas technology relies on Anti-Infective Conjugated Electrolytes (ACEs), a paradigm-changing platform that has been demonstrated to cure mice of untreatable superbug infections, representing the first new class of broad-spectrum antibiotics to be discovered in the past 50 years.

MemComputing: Disrupting high-performance computingCo-Founder and CEO: UC San Diego alumnus John Beane

MemComputing has developed software that achieves the speed and performance of quantum computing using patented, non-quantum technology. Computing problems that usually take hours, days and even weeks to solve can now be solved in minutes or seconds, according to co-founder John Beane. Only quantum computing has been perceived as being able to do this, but quantum computing is at least 10 years out. Our technology is available today, Beane says. Our SaaS (software as a service) is free to evaluate so no one needs to take our word for it. They can try it for themselves and make up their minds.

Myogene Bio: Cutting-edge gene therapies for muscle diseasesCo-Founder and CEO: UCLA alumna Dr. Courtney Young

Motivated by a desire to save lives, Myogene Bio is developing gene therapies for devastating muscle diseases. Their lead program, MyoDys45-55 has been shown in mice to be an effective treatment for Duchenne muscular dystrophy, a wasting disease for which there is currently no cure. MyoDys45-55 is designed to permanently fix the underlying cause of the disease, and could help half of all Duchenne patients. Dr. Young developed the gene editing platform that is the basis of MyoDys45-55 during her Ph.D. and postdoc work at UCLA. She was motivated by her cousin Christopher, who was diagnosed with Duchenne in 2008.

Sophies Bionutrients: Feeding a growing planet, sustainablyCo-Founder and CTO: UC Davis alumnus Kirin Tsuei

Sophies Bionutrients is a Singapore-based company that uses patent-pending fermentation technology to grow alternative protein from microalgae. Microalgae packs a protein punch and can be grown using far less land, water and energy than seafood or meat. Says co-founder Eugene Wang: Sophies Bionutrients is on a mission to unleash the limitless possibilities of nature, restore our planet and eliminate food allergies by creating plant-based, protein-rich alternatives to meat and seafood using microalgae, the mother of all food and plant life.

Squishy Robotics: A bouncy lifesaver for first respondersCo-Founder, CEO and CTO: UC Berkeley mechanical engineering professor Alice Agogino

Squishy robots sound like a lot of fun and in fact, these bouncy bots were inspired by a baby toy known as Skwish. Yet these little robots are built for business. They are squishy enough to survive being airdropped by drones into disaster zones. Equipped with visual, audio, chemical, biological, radiological and GPS sensors, they can quickly can send back vital information to human first responders and assist in the early rescue of victims.

SymSoil: Breathing new life into soil and farmingFounder and CEO: UC Berkeley alumnus Elizabeth Pearce

Most growers and farmers rely on chemical fertilizers and pesticides for the success of their crops. Not only are these synthetic materials expensive, but they can also harm soil fertility and reduce the flavor and nutrient density of crops. SymSoil is the first company to patent a process for large-scale production of biologically active compost that meets Soil Food Web specifications. Their goal is to restore soil health across the agricultural industry. SymSoils products improve plant yields, reduce plant pathogens and pests, cut costs and produce crops with superior flavor and nutrition.

We are inspired and excited to see the incredible startups competing in the UC Innovation Challenge, held in partnership with XTC, said Bill Tai, co-founder of XTC and partner emeritus, Charles River Ventures. The startups selected today exemplify the types of companies, technologies and innovations we are looking for in the fields of health care, clean tech, agriculture-food tech and robotics. The world is destined to be a better place tomorrow because of the groundbreaking work that they are doing today.

"As in the past, the UC Startup Innovation Challenge has produced stellar early-stageopportunitiesfrom acrosscampuses and sectors. We see this as further validation that university research will one day be considered an investable asset class of its own; and look forward to funding these companies as they achieve their goal of improving society leveraging technology, while creating financial returns to match, said Rafi Syed, partner, Bow Capital.

The 2021 Startup Innovation Challenge is supported by sponsorships from Ford Motor Company, The Office of the Chief Investment Officer of the University of California Regents, Bow Capital, the law firm ofOrrick, Herrington & Sutcliffe LLP, fintech company Brex andAmazon Web Services.

The 2021 UC Startup Innovation Challenge is a continuation of the I am a UC entrepreneur competition launched in 2016 to highlight the impressive work of the universitys student, faculty and alumni entrepreneurs. For more information about the contest and innovation driven by the UC system, visit ucinnovationchallenge.org.

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Meet the 10 disruptive technologies vying to win UC's Startup Innovation Challenge - University of California

In this recent webinar, Tim Latimer, founder and CEO of Fervo Energy shares details on how novel drilling techniques can scale up geothermal energy development.

In its webinar series EnergySource: Innovation Stream on new technologies with the potential to reshape the global energy system, the Atlantic Council Global Energy Center engages on discussionswith companies and individuals working diligently to bring those innovations to market at scale.On Thursday, December 17, 2020, the Global Energy Center hosted Tim Latimer, founder and chief executive officer of Fervo Energy, discussing how novel drilling techniques can scale up geothermal energy development.

With the right technologies, geothermal energy can play an important role in the energy transition. Tim Latimer discusses how Fervos design incorporates horizontal drilling and distributed fiber optic sensing to dramatically increase the productivity and lifetime of geothermal wells. He also described technological innovations that minimize the environmental impact of geothermal development while reducing costs.

You can listen into the webinar here:

Tim Latimer, founder and chief executive officer, Fervo Energy

Tim Latimer is the cofounder and chief executive officer of Fervo Energy. Fervo commercializes technology to develop, own, and operate geothermal assets as the dispatchable foundation to a 100% clean energy future. Tim began his career as a drilling engineer with BHP Billiton where he worked in the Permian and Eagle Ford basins. With a growing appreciation of the urgency and importance of climate change, Tim left the oil and gas industry 2015 to pursue an MBA and an MS in Environment and Resources from Stanford University and learn how to best contribute to the clean energy transition. Tim has also worked as a consultant for the Boston Consulting Group and as a consultant for startups Biota Technology and McClure Geomechanics. Tim is a fellow at Cyclotron Road and the Clean Energy Leadership Institute. He holds a degree in Mechanical Engineering from the University of Tulsa and is a proud native of Texas.

Source: Atlantic Council

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Webinar recording with Fervo Energy on key technologies to accelerate geothermal energy development - ThinkGeoEnergy