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Daily Archives: November 29, 2020
Woman’s Doctor: Knowing the symptoms of psoriatic arthritis – WBAL TV Baltimore
Posted: November 29, 2020 at 6:07 am
Woman's Doctor: Knowing the symptoms of psoriatic arthritis
Updated: 9:21 AM EST Nov 28, 2020
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LACEE: IN THIS MORNING'S WOMAN'S DOCTOR, KNOWING THE SYMPTOMS OF PSORIATIC ARTHRITIS, IT'S A DOUBLE WHAMMY OF AUTOIMMUNE DISORDERS. NOT ONLY DO PSORIATIC ARTHRITIS SYMPTOMS MIMIC THOSE OF PSORIASIS, LIKE PATCHES OF RED, SCALY SKIN, BUT THEY CAN ALSO CAUSE THE PAINFUL, SWOLLEN JOINTS THAT ARE COMMON WITH RHEUMATOID ARTHRITIS. THE SYMPTOMS CAN CHANGE FROM DAY TO DAY AND PERSON TO PERSON, MAKING PSORIATIC ARTHRITIS A PARTICULARLY TRICKY DISEASE TO DIAGNOSE AND MANAGE. MERCY MEDICAL CENTER DR. SADE YA KHAN SAYS THAT SYMPTOMS LEFT UNTREATED CAN LEAD TO PERMANENT JOINT DAMAGE. >> SYMPTOMS OF IT CAN BE INVOLVEMENT OF DIFFERENT AREAS OF THE SKELETON. IT COULD BE IN JOINT INVOLVEMENT, INCLUDING FINGERS AND FEET, WHICH WILL BE CONSIDERED SMALL JOINTS. IT COULD INVOLVE LARGER JOINTS, INCLUDING HIPS AND SHOULDERS. AND SOMETIMES, IT CAN ALSO AFFECT SPINE. LACEE: JOINING US THIS MORNING FROM MERCY MEDICAL CENTER, DR. JOSEPH CIO TOLA. THANK YOU FOR JOINING US. >> GOOD MORNING. LACEE: THIS SEEMS LIKE A PAINFUL CONDITION. TELL ME ABOUT THE BEGINNING SYMPTOMS OF PSORIATIC ARTHRITIS. >> IT'S SIMILAR TO REGULAR ARTHRITIS. JUST INFLAMED AND SWOLLEN, VERY SORE JOINTS. THEY GET A LOT OF FLUID BUILT UP ON THEM SOMETIMES. WE MANAGE THEM WITH CORTISONE INJECTIONS AND RELIEVING THE INFLAMMATION. LACEE: IS THIS SOMETHING THAT AFFECTS A CERTAIN GROUP MORE THAN OTHER? YOUNG OR OLD, MEN OR WOMEN? >> NO. NOT PARTICULARLY. IT CAN BE YOUNGER BECAUSE PSORIASIS CAN AFFECT YOUNGER PEOPLE. IT CAN AFFECT JOINTS AS WELL. LACEE: AT WHAT POINT IS IT TIME TO TALK TO A DOCTOR. IT CAN BE CONFUSED WITH PSORIASIS AT FIRST OR ARTHRITIS. >> WHEN SOMEBODY HAS PSORIASIS AND THEIR JOINTS BEGIN TO HURT, I THINK THAT'S THE TIME WHERE THEY NEED TO REALLY GET AGGRESSIVE WITH TREATING IT. LACEE: IN TERMS OF TREATMENT, WHERE DOES TREATMENT START FOR IT? >> IT STARTS WITH MANAGING THE INFLAMMATION. SO THEY WOULD SEE EITHER THEIR DERMATOLOGIST OR THEIR REGULAR PHYSICIAN TO GET ON ANTIINFLAMMATORY REGIMEN. AND THEN WHEN IT COMES TO THE POINT WHERE THEY'RE READY FOR AN ORTHOPEDIC SURGEON, WE BEGIN MANAGING IT BY CONTROLLING THE INFLAMMATION AT THE JOINT LEVEL WITH INJECTIONS. LACEE: WHAT KIND OF POSSIBLE SURGERY COULD THIS LEAD TO? >> IT LEADS TO JOINT REPLACEMENT. IT'S VERY SIMILAR TO RHEUMATOID ARTHRITIS. WHEN THE CARTILAGE IS ERODED ENOUGH AND THE JOINT CAN'T RECOVER, WE REPLACE IT. LACEE: IS IT SOMETHING THAT YOU CAN CURE? >> NO, IT'S JUST MANAGEMENT. IT'S MANAGEMENT OF THE INFLAMMATION. LACEE: WHAT CAN YOU DO TO PREVENT IT IN THE FIRST PLACE? >> I MEAN, I THINK YOU WANT TO BE AS HEALTHY AS POSSIBLE. ANTIINFLAMMATORY DIET AND DOING THE BEST YOU CAN TO CONTROL SUGAR AND INFLAMMATORY PRODUCTS IN YOUR LIFE STYLE. BUT THAT'S REALLY ABOUT IT. LACEE: GOT TO STAY HEALTHY. >> IT'S NOT SOMETHING WE CAN CURE. LACEE: THIS TIME OF YEAR IS HARD BECAUSE THERE'S A LOT OF SUGAR AND THAT STUFF IN FRONT OF US. THANKS FOR TAKING TIME OUT OF YOUR MORNING TO JOIN US. APPRECIATE
Woman's Doctor: Knowing the symptoms of psoriatic arthritis
Updated: 9:21 AM EST Nov 28, 2020
Psoriatic arthritis is a double-whammy of autoimmune disorders. Not only do psoriatic arthritis symptoms mimic those of psoriasis -- like patches of red, scaly skin -- but they can also cause the painful, swollen joints that are common with rheumatoid arthritis. Mercy Medical Center's Dr. Joseph Ciotola explains.
Psoriatic arthritis is a double-whammy of autoimmune disorders. Not only do psoriatic arthritis symptoms mimic those of psoriasis -- like patches of red, scaly skin -- but they can also cause the painful, swollen joints that are common with rheumatoid arthritis. Mercy Medical Center's Dr. Joseph Ciotola explains.
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Woman's Doctor: Knowing the symptoms of psoriatic arthritis - WBAL TV Baltimore
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Maradona flew and fell. It is why we loved him – The Straits Times
Posted: at 6:07 am
As a young man in Kolkata in the late 1980s, my friends and I managed to get our hands on a videotape of Hero, the official film of the 1986 World Cup. Diego Maradona's complexity as a man was yet to fully emerge and we were novice writers bewitched by this booted man. We watched him so often that we wore out the videotape. But memory of magic is always beyond erasure.
If we didn't have time for the whole film, we pressed forward wind till we came to the goal. That goal. The one which is an 11-second hymn to skill and a roughly 60m run into immortality. The goal that comes four minutes after the Hand of God and is the Left Foot of Genius. Sometimes you wish the ball could tell the full story of every spin, nudge, idea and caress.
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Maradona flew and fell. It is why we loved him - The Straits Times
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T-rays help to characterise psoriasis and skin cancer – The Engineer
Posted: at 6:07 am
The diagnosis and treatment of skin conditions such as eczema, psoriasis and skin cancer could be improved by using T-rays to analyse the structure of skin.
This is the claim of scientists from Warwick University and The Chinese University of Hong Kong (CUHK) who have built a more detailed picture of the skins structure and hydration levels by analysing T-rays fired from several different angles.
Warwick leads breakthrough in terahertz imaging
Their method, detailed inAdvanced Photonics Research, could provide a new tool for scientists and clinicians for characterising the properties of skin in individuals.
Sitting between infrared and WiFi on the electromagnetic spectrum, T-rays (Terahertz (THz)) radiation sees through plastics, ceramics and clothes. They are non-ionising also, so safe for use in biological settings.
Only the T-rays passing through the outer layers of skin (stratum corneum and epidermis) before being reflected back can be detected, making T-ray imaging a potentially effective way of monitoring these outermost layers. The University said that to test this, terahertz light is focused onto the skin via a prism to align the ray in a particular focal plane. Depending on the properties of the skin, that light will be reflected back slightly differently. Scientists can then compare the properties of the light before and after it enters the skin.
Limitations in standard THz reflection spectroscopy were overcome by using ellipsometry, which involves focusing T-rays at multiple angles on the same area of skin.
By using ellipsometry they could accurately calculate the refractive index of skin measured in two directions at right angles to each other. The difference between these refractive indices is termed birefringence and the research marks the first time that the THz birefringence of human skin has been measuredin vivo.
Professor Emma Pickwell-MacPherson, from the Department of Physics at Warwick University and the Department of Electronic Engineering at CUHK, said: We wanted to show that we could doin-vivoellipsometry measurements in human skin and calculate the properties of skin accurately. In ordinary terahertz reflection imaging, you have thickness and refractive index combined as one parameter. By taking measurements at multiple angles you can separate the two.
Hydrated skin will have a different refractive index from dehydrated skin. For people with skin disorders, well be able to probe the hydration of their skin quantitatively, more so than existing techniques. If youre trying to improve skincare products for people with conditions like eczema or psoriasis, we would be potentially be able to make quantitative assessments of how the skin is improving with different products or to differentiate types of skin.
For skin cancer patients, you could also use THz imaging to probe the skin before surgery is started, to get a better idea of how far a tumour has spread. Skin cancer affects the properties of the skin and some of those are unseen as theyre beneath the surface.
To test their method, volunteers placed their arm on the imaging window of their T-ray equipment for 30 minutes, after acclimatising to the ambient temperature and dryness of the laboratory. By holding their skin against the surface of the imaging window, they blocked water from escaping from their skin as perspiration, a process called occlusion.
The researchers then made four measurements at right angles to each other every two minutes over half an hour, so they could monitor the effect of occlusion. Because T-rays are particularly sensitive to water, they could see a noticeable difference as water accumulated in the skin, suggesting that the method could show how effective a product is at keeping skin hydrated.
Further research will look at improving the instrumentation of the process and how it might work as a practical device.
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#ComicBytes: The comic book origin of Nick Fury | NewsBytes – NewsBytes
Posted: at 6:07 am
Nick Fury is the thread that holds the entire Marvel Cinematic Universe (MCU) together. After all, he is the one who started the Avengers initiative in MCU.
However, his story is a bit different in comics. For starters, there are different versions of Nick Fury in the multiverse.
To know the origin of the character, we will begin with the original- Nick Fury Sr.
The original Nick Fury was Caucasian and made his debut in the WWII comic called Sgt. Fury. He later fought in the war alongside Captain America while leading the legendary Howling Commandos.
Working with the CIA in the 60s, Fury later became the director of S.H.I.E.L.D. to fight evil organizations like Hydra and A.I.M.
This version was retired by Marvel.
The Ultimate Marvel Universe is the Marvel Universe in an alternate timeline. Nick Fury in this Universe was also a WWII veteran and Director of S.H.I.E.L.D, but with a complicated personality.
Interestingly, here Fury is Black, and his design was inspired by Samuel L. Jackson, who went on to become the onscreen Nick Fury, five years after the comic series was released.
After the immense popularity of the Ultimate and MCU version, Marvel brought in the original Nick Fury's secret son, Nick Fury Jr. or Marcus Johnson.
A former Army Ranger, Johnson discovered his true identity and joined the S.H.I.E.L.D to carry on his father's name and legacy.
He is currently a top operative in the organization, alongside his best friend Phil "Cheese" Coulson.
In Captain Marvel, Goose The Flerken snatched out Fury's eye. But in the comic versions Fury Sr. loses his eye to a Nazi grenade blast, Ultimate Fury loses it in an explosion during the Gulf War and Fury Jr. had his eye cut out.
They also got limited immortality from the Infinity formula (super-soldier serum in the Ultimate version).
As mentioned before, Marvel has retired Nick Fury Sr. to pave way for his son. The Ultimate version also doesn't exist anymore as this Universe disappeared after the Secret Wars.
Nick Fury Jr. might be the only Fury in the current continuity, but he represents the previous Furys in terms of being a badass, a great strategist, and an important part of S.H.I.E.L.D.
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Never Seen Before Tolkien Works Will Be Published In 2021 – Unreserved Media
Posted: at 6:07 am
Lovers of Middle-earth rejoice, because next year there may be more to read of the magical land that has become beloved internationally by so many. This new collection explores the heart of the land filled with elves, dwarves, hobbits and magic in only the way Tolkien can satisfy.
The collection, titled The Nature of Middle-earth, covers themes including Elvish immortality and reincarnation as well as the geography of places where some of Tolkiens most famous epic fantasies were set.
Which is no surprise considering how much thought he put into the description of every path and woodland mystery in the Fellowship of the Ring when Frodo and gang leave the Shire for the first time.
Not only will this collection give more depth to the already considerable Middle-earth legendarium, but it may also even settle the long-running debate among readers about whether dwarf women had beards. Which will hopefully quell the debate thats been raging on Reddit for years.
Considered one of the founding fathers of modern fantasy, Tolkien is best known for his novels The Hobbit and The Lord of the Rings, published in 1937 and 1954-1955. Translated in over 70 languages, the books are international bestsellers made even more famous by the well-received Hollywood trilogies directed by Peter Jackson.
The British author didnt stop there, he continued to write about Middle-earth in the following decades, right up until the years preceding his death in 1973. Tolkiens love for developing the land and its lore is obvious to anyone who delves into his literature.
For him, Middle-earth was part of an entire world to be explored, and the writings in The Nature of Middle-earthreveal the journeys that he took as he sought to better understand his unique creation, Deb Brody, vice-president of Houghton Mifflin Harcourt explains.
After his death, his son Christopher Tolkien worked on editing and putting together many of his unpublished works as his literary executor. Much of his writing was in pen and on scraps of paper, some drafts written over other drafts. From the manuscripts, he managed to publish various works such as The Silmarillion, The Children of Hrin andmore recently The Fall of Gondolin.
With Christopher having passed away earlier this year, The Nature of Middle-earth has been edited by Carl F. Hostetter, one of the worlds leading Tolkien experts and respected head of the Elvish Linguistic Fellowship. This international organisation, founded in 1988, studies the fictitious languages imagined by J.R.R. Tolkien.
To get ready for the new information, take a little journey through Middle-earth with this extensive interactive map created by chemical engineer Emil Johansson here.The book itself is due out 24 June 24 2021, and is published by HarperCollins in the UK and Houghton Mifflin Harcourt in North America.
Source: AFP Relax News
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New Lord Of The Rings Book Announced, Will Reveal Who Can Grow Beards – GameSpot
Posted: at 6:07 am
A new book feature the unpublished writings of Lord of the Rings author J.R.R. Tolkien is coming in 2021. Harper Collins has announced "The Nature of Middle-earth," and it will shed light on a number of particulars about Middle-earth and its inhabitants.
Specifically, the book will provide more details on the creatures who live in Numenor, Elvish immortality and reincarnation, and the powers of the Valar. But all of this pales in comparison to the most important fact that the book will confirm: who can grow beards.
Harper Collins said the book represents a "veritable treasure-trove offering readers a chance to peer over Professor Tolkien's shoulder at the very moment of discovery: and on every page, Middle-earth is once again brought to extraordinary life."
The Nature of Middle-earth is edited by Tolkien scholar Carl Hostetter and it's due for release on June 24, 2021.
This will be just the latest book that dives deep into the extended lore of Middle-earth. Some of Tolkien's previous writings were published in books such as Unfinished Tales, The History of Middle-earth, and Beren and Luthien, among others. These were all edited by Tolkien's son, Christopher, who passed away in January this year.
The Lord of the Rings remains very popular today. Amazon is currently filming a very expensive TV show based on the fantasy series in New Zealand, while there are multiple Lord of the Rings video games in the works, including an MMO and a title featuring Gollum.
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Reminiscing grandmother during days of coronavirus – Hurriyet Daily News
Posted: at 6:07 am
If there is something that is common to a big number of people right now is fear. Fear is always there, of course, and it is part of our existence. But usually, fear is accompanied by the object of fear. I am afraid of The more specific the object of our fear, the more we could rationalize and gather strength to combat it. The less specific it is, the more difficult it becomes for us to organize ourselves to fight it.
For example, my grandmother was very practical about it. She was always religious, attending mass when she should and when her neighbors would see that she did. As a widow for over forty years, with two living children of the three that she brought to the world, she had to care for her social integrity as well as fending for her family. So, for most of her life, her relationship with God, death, afterlife, and all the rest, was more let us say, practical. She attended all the rites she had to, lit candles for her lost third child who died at the age of five of meningitis, for her husband and her in-laws. She fasted throughout the 40 days of Lent before the Orthodox Easter and never missed weddings, baptisms and funerals.
When she stepped into her 80s, she became more philosophical. Having attended only the first three years in a primary school, her reading capacity was limited. Yet, like all women of her age in their 80s, they know the New Testament almost by heart and there is nothing more that they need. The rest of her intellectual needs was fulfilled by her enormous capacity to recite rhyming proverbs and fairy tales full of poetic imagery and philosophical perceptions. It was during that period, the last decade of her life when she took death seriously. I mean as a logical possibility. And she devised a daily method of dealing with it, a method which was connected with the time factor. So, she started a ritual of daily prayers of thanks that she would do twice a day - one after waking up every morning to thank God for she is alive, and the second before she went to bed for having lived one more day. Even at her very end, she kept at least part of this ritual alive although her brain had already abandoned her.
Why did I think of her? Obviously, because of our current relationship with the fear of COVID-19, a constant underlying fear of being the next victim of this creature, which looks like a surreal colorful sea urchin, and can choose any of us at any moment to put an end to our life. And it is not a real fear that we feel. It is also not a deep feeling of the unavoidable human fate like the one that my grandmother felt and tried to exorcize through her daily prayers of thanks.
The worst is that we are not even afraid of being the next victim; we are in that middle-of-the-road situation where we cannot organize our psychology. We have become desensitized to it but are sure of our self-importance and immortality in this world, unlike my grandmother, who thought that every extra day in her life was a gift.
coronavirus,
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Psoriasis Flares Following Systemic Glucocorticoid Exposure in Patients With a History of Psoriasis. – Physician’s Weekly
Posted: at 6:07 am
To our knowledge, this study is the first to assess the rate of any type of psoriasis flare during or immediately following the administration of systemic corticosteroids in patients with a known history of psoriasis.To determine the rates and types of psoriasis flares during or within 3 months after concluding systemic corticosteroid administration in adult patients with a known history of psoriasis.This retrospective cohort study assessed adult patients (18 years at the time of psoriasis diagnosis) evaluated in the Marshfield Clinic Health System (Marshfield, Wisconsin) with an established diagnosis of psoriasis and exposure to at least 1 systemic corticosteroid from October 31, 2012, to July 1, 2018. Exclusion criteria were patients younger than 18 years, patients with a diagnosis of psoriatic arthritis, and patients receiving only topical, intraarticular, or intrabursal corticosteroids.The primary outcome was rate of psoriasis flares during or within 3 months of discontinuation of the patients first course of systemic corticosteroids. Secondary measures included rates of specific types of psoriasis flares, including pustular, erythrodermic, and worsening plaque stage psoriasis.Of 516 cohort patients, 288 (55.8%) were women, and the mean (SD) age at first psoriasis diagnosis was 49.6 (17.0) years. Among 1970 patients with a diagnosis of psoriasis before receiving systemic corticosteroids, a 1.42% (95% CI, 0.72%-2.44%) psoriasis flare rate of any type was identified when prescribed their first course of systemic corticosteroids. Further stratification identified only 1 severe flare (erythroderma) among all flares reported, with no pustular psoriasis flares identified (0.07%; 95% CI, 0.00%-0.26%).In this study, the rates of psoriasis flares were low, especially for severe psoriasis flares. Our results suggest that systemic steroids may be much less likely to trigger severe flares in patients with psoriasis than what is traditionally taught in dermatology.
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Sean Connery: Bond and superstar – Frontline
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HE seemed like a demented ogre, massive and dangerous, looming over his hapless, emotionally battered wife. Talking through clenched teeth, his body about to burst forth in uncontrollable violence as insanity takes over completely, he growls: Ill make you happy, you said. You bloody didnt. The pitiless brutality, anger and madness in that little domestic scene is the terrifying and disturbing portrayal of an honest but flawed mans dark descent into insanity. This balding, middle-aged, slightly overweight man whom Sean Connery played with frightening authenticity in Sydney Lumets The Offence (1973) proved to be a turning point in the actors career.
It was hard to visualise that this same man had played the dapper, deadly British spy James Bond in the film just before this for the sixth time, the colossal hit Diamonds are Forever (1971). But he had had enough of the role. At the height of his popularity as Bond, with multimillion-dollar contracts for two more films awaiting his signature, he walked away and sought to shatter the typecast by playing a role like the one in The Offence. His abilities were never in doubt, but Lumets film put him firmly on the road to celluloid immortality. He had cast away James Bond just like the toupee he had been wearing for the part and was now ready for any role of his choosing.
But for many, Connery will always be the first and the definitive James Bond. His passing away on October 31 brought to an end an era he defined by his overtly masculine presence, impeccable style, prodigious talent and magnificently expressive eyebrows. He was 90 and is survived by his wife, Micheline Roquebrune, and son, Jason. Bond may have catapulted Connery into international stardom, but he was much more than that. He was a consummate artist who played a wide range of characters and established himself as one of the finest actors of his generation. As a superstar, he was second to none.
Born Thomas Sean Connery on August 25, 1930, in Edinburgh, Scotland, Connery spent his childhood in abject poverty. As an infant, his crib was the bottom drawer of a wardrobe, and before he was 10, he was already an important earner for his family. In the mornings he would deliver milk and in the evenings he worked as an assistant to a butcher. School meant little to him in his situation. He joined the navy when he was around 16, learnt to box and was honourably discharged by the time he was 19 after being diagnosed with a stomach ulcer. By that time, he was an able-bodied young man, standing 62, with irresistible dark gypsy features. He flitted from job to job, working as a coal delivery man, a road construction worker, and a French polisher. At the same time, he took up bodybuilding in a serious way, which facilitated his first foray into the world of acting. Initially, he served as a muscular prop standing in the background and from there went on to get bigger roles.
His stage career may not have been much of a success, but it paid the bills and paved the way for bit parts in television series. One of his notable roles during this period of obscurity was that of the over-the-hill boxer Mountain McClintock in the play Requiem for a Heavyweight for the BBCs Saturday Night Theatre in 1957. This was the same role that Anthony Quinn would immortalise in the film version five years later, with the character renamed Mountain Rivera. Connery was no Quinn, but he was still good enough to be noticed and remembered. The performance did not yield immediate results as far as his acting career was concerned. He played whatever part came his way, including one of the villains in a 1959 Tarzan film who died ingloriously with an arrow pierced through his stomach.
After languishing in celluloid obscurity for several years, he got his big break when the producers Harry Saltzman and Albert R. Broccoli saw in him the James Bond of their vision. Interestingly, after Saltzman and Broccoli selected him to play Bond in the first movie of the franchise, Dr. No (1962), and sent some footage of Connery to United Artists, the production house got back to them with a terse cable that said: SEE IF YOU CAN DO BETTER. Even Connerys good friend Michael Caine was surprised at the choice. I was sure theyd give it to Rex Harrison because he was your living image of upper-crust good-living, Caine had said. But Saltzman and Broccoli had already made up their minds. They just loved the way Connery moved. United Artists precept was ignored, and almost from the very moment in the film when Bond introduces himself in a bored, deadpan tone, almost imperceptibly raising an eyebrow, a cigarette dangling laconically from his sardonic lips as Bond, James Bond, Connery as Bond became a worldwide sensation. If the author Ian Fleming created the character, Connery created the cult.
There have been other starsRoger Moore, Pierce Brosnan and Daniel Craigwho interpreted the role of Bond in their own way and to huge box-office success, but Connery remained the benchmark to judge all future Bonds. He was after all the first, the one who set the standard. He was also, arguably, the finest actor to play Bond. Connery was to play Bond seven times to huge popular acclaim. After Dr. No came From Russia With Love (1963), Goldfinger (1964), Thunderball (1965) and You Only Live Twice (1967).
After playing the role in five consecutive films, Connery sought something different, and the part went to the Australian actor George Lazenby for On Her Majestys Secret Service (1969). Although the film was a hit, it was Connery that the public wanted as Bond again, and in 1971, he returned for the sixth time, in Diamonds are Forever. It would be another 12 years before a middle-aged Connery would reprise his role as the super spy for the final time, in Never Say Never Again (1983). It was a monster hit, earning $10,958,157 in the first four days itself, a record at that time for Bond films. Connery, then 52, showed that he could still teach the newer, younger audience a thing or two about old-school machismo.
But the interesting thing about Connerys Bond was that he was not just a macho action man. Although darker and more violent than Flemings creation, Connerys representation was also subtle, with an underlying sense of comic irony. At one level, it may even seem that Bond was mocking his own image. Lumet, with whom Connery did five movies, once said of his acting as Bond: Non-professionals just didnt realise what superb high-comedy acting that Bond role was.
Connerys Bond was also the hero at a time when unapologetic chauvinism on the screen was not unfashionable. Angry young men of literature such as Alan Sillitoe and John Osborne were creating unrepentant angry young men in the pages of books and for the stage: for example, the scornful, misogynistic Jimmy Porter in Osbornes Look Back in Anger (published and staged in 1956 and made into a movie starring Richard Burton in 1969), or the philandering, rebellious young Arthur Seaton in Sillitoes first novel, Saturday Night and Sunday Morning (published in 1958 and made into a film starring Albert Finney in 1960). In the given cultural scenario, nobody defined over-the-top masculine chauvinism more blatantly (sometimes, quite embarrassingly) than Connerys Bond. In You only Live Twice, when the Japanese character Tanaka informs him that the women in the spa (in the scene) were fascinated by his chest hair, Connerys Bond quips with a smirk: Japanese proverb say bird never make nest in bare tree.
Neither Connery nor his Bond was particularly known for political correctness. In an interview Connery gave in the 1960s in the midst of Bond mania, he said: I dont think there is anything particularly wrong about hitting a woman, although I dont recommend doing it in the same way that youd hit a man. Even some 20 years later, when the world had changed, Connery remained steadfast in his point of view. I havent changed my opinion, he told Barbara Walters in an interview in 1987. Finally, after another 20 years, Connery put an end to the controversy by saying: My view is I dont believe that any level of abuse against women is ever justified under any circumstances. Full stop. Perhaps because it was Connery who made those comments, the public never made too much of them. Other stars would not have gotten away with it so easily.
After the success of the first Bond, it would have been easy for Connery to have gotten typecast. However, the actor in him could never be satisfied with stardom alone. In 1962, when he signed a five-year contract to star as James Bond, he was allowed to make one non-Bond movie a year. Connerys choice of films during that period demonstrated his need to expand his creative boundaries and challenge himself. In between the Bond movies, he played the scheming Anthony Richmond in The Woman of Straw (1964), the considerate and intuitive husband to Tippi Hedren in Alfred Hitchcocks underrated classic Marnie (1964), the rebellious Joe Roberts in Lumets war drama The Hill (1965), and the gifted but psychologically disturbed poet Samson Shillitoe in A Fine Madness (1966). He also did a Western, Shalako (1969) with the French siren Brigitte Bardot. When Connery walked out of the Bond franchise after Diamonds are Forever, it shocked moviegoers of the time as the screen character was at the height of his popularity. However, it was only after he quit Bond that Connery came into his own as a multifaceted actor.
His first post-Bond movie, Lumets dark neo-noir crime drama The Offence, was a calculated risk that paid off. It was not a role bankable leading men of Hollywood would have chosen, but it established Connery as an acting powerhouse as well as a huge box-office draw. This was his third movie with Lumet. After making The Hill, he acted in The Anderson Tapes (1971) and went on to act in two more Lumet films: Murder on the Orient Express (1974) and the comedy Family Business (1989), where he played the loveable rogue Jessie McMullen trying to tempt his grandson into a life of crime.
Connery was one of a rare breed of actors whose star never showed any signs of setting. In the 1970s, he went on to act in such classics as John Hustons The Man who would be King (1975) and Richard Lesters Cuba (1979). He played an aging Robin Hood opposite the ever-elegant Audrey Hepburn in the unlikely hit Robin and Marian (1976) and Raisuli, the Arab chief of a group of insurrectionists, in the epic adventure movie The Wind and the Lion (1975) opposite Candice Bergen.
As he grew older, besides playing the lead, he comfortably shifted into doing important supporting roles. Just as he was brilliant as Father William of Baskerville, the detective priest in The Name of the Rose (1986)for which he won a BAFTA (the British Academy for Film and Television Arts) for Best Actorhe was equally great in his supporting role as Jim Malone in Brian De Palmas The Untouchables (1989). As Malone, he was tough, funny, sentimental and fiercely loyal. No one but Connery, with his gigantic frame and a sly humorous glint behind those honest eyes, could have done justice to the role. He won his first and only Academy Award (for Best Supporting Actor) for it.
Even in his sixties, he continued to deliver hit movies such as The Hunt for Red October (1990), Rising Sun (1993) and The Rock (1996). He could hold his own in action movies with contemporary stars such as Wesley Snipes and Alec Baldwin, and he could also steal the show with his inimitable comic technique as he did in Steven Spielbergs Indiana Jones and the Last Crusade (1989), in which he played Harrison Fords father. That same year, the 59-year-old Connery was voted The Sexiest Man Alive in People magazine, making him the oldest Sexiest Man Alive ever.
For all his fame and the accolades he received (an Oscar, a BAFTA, two Golden Globes, the Cecil B. DeMille Award and the AFI (American Film Institute) Life Achievement Award), he often took a pragmatic and professional approach to accepting roles. He did not immediately agree to acting in Dr. No as he was also contemplating a long-term contract for a television series at that time. The years of deprivation had taught him the value of money, and throughout his life he was careful in his investments and was never reckless. He even used to joke about his alleged money-mindedness. While accepting his Oscar, he said: I had decidedif I had the good fortune to winto give it [the Oscar statuette] to my wife but this evening I discovered backstage that there was $15,000, and now Im not so sure. From a nine-year-old boy earning money for his family in the slums of Edinburgh to being knighted and hailed as one of the greatest cinema stars of all time, the proud Scotsman had indeed come a long way.
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Dermatology a bellwether of health inequities during COVID-19 – American Medical Association
Posted: at 6:06 am
Dermatologic conditions are routinely overlooked and misdiagnosed in people of color. The COVID-19 pandemic provides another notice of why dermatology training needs urgent updating.
During a recent Ethics Talk videocast from the AMA Journal of Ethics (@JournalofEthics), Jenna Lester, MD, assistant professor of dermatology at the University of California, San Francisco, School of Medicine talked about why COVID toes should bring physicians attention to long-standing health inequities.
Accounting for differences
The most well-known dermatologic manifestation of COVID-19 is COVID toes, a purplish-red discoloration of the tops and tips of the toes. There are other cutaneous manifestations, such as papulosquamouseruptions, pityriasis rosea-like eruptions and more vasculitic-type lesions.
"A lot of these have a basis of inflammation, and inflammation appears differently in different tones of skin, Dr. Lester said. So what may look red or pink in someone with light skin may actually look purple to blue, or darkerdark brown evenin someone with darker skin. So if your eye is not trained to recognize these things in different skin tones, it might be quite easy to miss it.
The good news
If properly trained, however, physicians can help patients keep an eye out for skin signs of COVID-19 infection.
One of the great things about the skin is that it's an external organ that patients can look at with us, she said. So if doctors, and then subsequently patients, are aware of the manifestations in all different skin tones we might be able to say, If you notice something like this on your skin, this could be an early sign of COVID-19. You should consider sheltering in place, self isolating, getting testing if you can.
Check out how to tackle health inequities with science, data during pandemic.
Whats in the way
The problem is that most physicians are not, in fact, trained to recognize dermatologic conditions in varying skin tones, Dr. Lester said. Most of the photos in medical education textbooks, for example, show white patients.
We need to think about increasing representation in our photographs in dermatology specifically, she said, adding that terminology is important too. So we're not saying the salmon pink patches of psoriasis are classic presentations of psoriasis, because psoriasis in someone with dark skin does not look like that.
But there are also systemic forces in play, Dr. Lester noted. Economics, for example, plays a role in patient access: Dermatology is a lucrative specialty, and many dermatologists do not accept Medicaid.
Dr. Lester started a skin-of-color clinic at UCS, that provides high-quality dermatologic care for Black, Latino, Asian, Native Indian and Pacific Islander communities.
Theres research that suggests that patients of color, particularly Black patients, appreciate having a dermatology space that is built for them. They feel better getting care in a skin of color clinic than in a general dermatology clinic, she said. My ultimate goal would be that these clinics don't have to exist, that we're able to provide this same type of care where patients feel as comfortable in any dermatology setting. For now, I think it's important to create a place where these patients feel comfortable coming and returning to.
For a model like this to work at a wider level, though, the system itself needs to change, Dr. Lester noted.
We know that there are fewer Black men in medical school now than there were in the 70s, she said. So how can we, as a profession, diversify the people who make up our professionthat we have a diversity of thoughts and ideas and approaches to problems and solutions, as well? I really think that that is central to solving a lot of these issues.
Check outprevious episodesof the Ethics Talk podcast or subscribe to the series iniTunesor other services.
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Dermatology a bellwether of health inequities during COVID-19 - American Medical Association
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