Daily Archives: November 22, 2020

On 17 November 2020, Novartis registered a Phase III psoriatic arthritis (PsA) clinical trial of its IL-17 inhibitor Cosentyx (secukinumab) compared against Johnson & Johnsons Stelara (ustekinumab). The 28-week study is expected to be completed in 310 subjects who have failed treatment with a tumor necrosis factor (TNF) inhibitor, and the studys primary endpoint is the Health Assessment Questionnaire-Disability Index (HAQ-DI). With the plethora of biologic therapies available, post-marketing head-to-head clinical trials are a critical method through which prescribers can compare drugs directly against one another. The registration of this trial demonstrates Novartis continued efforts to solidify its position in an increasingly crowded market.

Although Novartis has committed significant resources towards marketing Cosentyx, the last few years have brought bad news to the brand from head-to-head comparator trials in the rheumatology space. This latest trial in PsA comes one year after the news that Cosentyx failed to demonstrate statistically significant improvement compared with AbbVies TNF-inhibitor Humira (adalimumab) in the Phase III EXCEED Trial (NCT02745080), sponsored by Novartis themselves. The company had hoped Cosentyx would demonstrate statistically significant superiority measures in terms of its primary endpoint, the American College of Rheumatology score of 20% improvement (ACR20), a measure that would have made them serious contenders for first-line therapies especially given the 2019 EULAR guideline revisions. The change in the primary endpoint is likely a reflection of Novartis desire to avoid a repeat performance in this trial, focusing on a quality of life measure instead of clinical improvement.

After the TNF-inhibitors, J&Js Stelara is a PsA market leader and incredibly popular with dermatologists, who work closely with PsA patients and their rheumatologists to manage both aspects of their disease. Cosentyx, which was approved in PsA in 2015, was a fast rising star in the PsA disease space for several years. However, success in this latest trial is critical to ensure its future in the field. Although Cosentyx had an advantage by being first-in-class, Eli Lillys Taltz is right on its heels with several positive head-to-head results in tow.

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Registration of head-to-head psoriatic arthritis clinical trial begins the battle for second place - Clinical Trials Arena

18 November 2020, 13:58 | Updated: 18 November 2020, 16:23

The former Oasis frontman has revealed he's taken to wearing protection on his hands as he describes his skin condition as "raging".

Liam Gallagher has resorted to wearing gloves around the house after a flare up of psoriasis.

The former Oasis frontman has previously revealed he has the skin condition, but this week took to Twitter to let his followers know it was "raging".

Asked by a fan what he was up to today, the Supersonic singer replied: "Cleaning the house my psoriasis is raging so wearing gloves all day".

Fans were quick to share their sympathies and remedies with the Manchester rocker, as others revealed they also suffer with the same condition, which can flare up in winter.

It's not the first time Gallagher has talked about the psoriasis, previously recalling a funny story involving a festival-goer at the band's first Glastonbury appearance who mistook the flakes on his shoulders for cocaine.

"I remember coming off stage and I got my clothes robbed," he told Noisey back in 2017. "I [also] remember meeting someone, some very strange kid, who come up to me and thought I had cocaine in my hair."

He explained: "I got psoriasis [skin condition that causes itchy, scaly rashes] so I had obviously been scratching it during the day and that, and there were little white bits and shit.

"They were takingit out of my hair and putting it on their gums and putting it up their f***ing nose!"

READ MORE: Liam Gallagher announces All You're Dreaming Of single

Meanwhile, Gallagher is preparing to release his festive new single All You're Dreaming Of, which is set fo release on 27 November.

Net proceeds from each download and stream will go to the leading charity, Action For Children, from the day of release until 31st December 2020.

Gallagher said of the track: "All Youre Dreaming Of is an instant classic that is perfect for this time of year. Considering the year that weve all had, I hope this brings back some much needed love and hope. Bing Crosby would have been proud."

READ MORE: Liam Gallagher supports University of Manchester students

Last month also saw Liam announce the details of his Down By The River Thames livestream, which will take place on 5 December.

The show promises to include iconic songs from throughout his career with Oasis as well as his new solo hits and some surprises in between.

The Wall of Glass singer said of the event: "To all my brothers and sisters around the world. I'm performing a one-off celestial live performance for you to stream, 'Down By The River Thames', on 5th December 2020. I'll be performing tracks from my two number 1 solo albums as well as some stone cold Oasis classics, some of which you haven't heard me sing for a long, long time. C'mon you know. LG x".

Stream 1 Saturday 5 December 8pm GMT for UK, Ireland and Europe.

Stream 2 - Saturday 5 December 8pm ET for East Coast North America and South America.

Stream 3 - Saturday 5 December 8pm PT for West Coast North America and Central America.

Stream 4 - Sunday 6 December 8pm AEST for Australia, New Zealand and Asia.

READ MORE: Which Oasis songs did Liam Gallagher write?

Read the rest here:
Liam Gallagher resorts to wearing gloves to cope with psoriasis flare-up in lockdown - Radio X

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Comprehensive Report on Psoriasis Treatment Market 2020 | Size, Growth, Demand, Opportunities & Forecast To 2026 | Sun Pharmaceutical Industries...

If you have psoriatic arthritis and work from home, its important to adjust your workspace to fit your needs. Pain and stiffness especially in the elbows and hands are common complaints, due to the repetitive motions involved in some office tasks and sitting in the same position all day. But making the right adjustments can help ease neck and lower back pain as well as joint pain and swelling that could otherwise make it hard to sit at a desk for hours.

An ergonomically correct workspace can help ease joint symptoms and reduce fatigue from spending extended periods of time in uncomfortable positions. Ergonomics is the science of fitting the task to the worker to maximize productivity while reducing discomfort, fatigue, and injury, says Natalia Ruiz, a physical therapist and certified office ergonomics evaluator with Rusk Rehabilitation at NYU Langone Health in New York City. Having an ergonomic setup ensures you work in neutral postures that reduce strain in your joints and tissues already affected by psoriatic arthritis. Therefore it can reduce your symptoms or reduce the risk of developing them [in the first place].

Proper support and good body mechanics can help prevent compensatory movement patterns that can lead to increased pain and stiffness, adds Jamie Hilker, an occupational therapist and certified hand therapist at Mayo Clinic in Rochester, Minnesota.

If you work a full-time job and require new equipment to make your home office more psoriatic arthritis friendly, talk to your employer. The Social Security Administration considers psoriatic arthritis a disability, and the Americans with Disabilities Act (ADA) requires employers to make reasonable accommodations that enable full-time employees to perform their essential job functions.

Reasonable accommodations may include physical changes to your workspace and accessible and assistive devices. That includes anything you need to be comfortable and productive at your job, such as special equipment you need. While these requirements dont always cover purchasing specific expensive equipment, your employer may be eligible for tax credits if they do supply you with accommodations.

In many cases, small adjustments to your workstation can make a big difference. Here are a few tips to help you set up a psoriatic arthritisfriendly home office.

An occupational or physical therapist who has knowledge in office ergonomics can help you design and modify your current home office space. These therapists specialize in adapting your environment to your abilities to help you better perform daily activities and reach your goals. They assess your particular setup, listen to your needs, and make recommendations based on observation and research, says Ruiz.

Hilker recommends looking for a licensed and registered occupational therapist or certified hand therapist. Ruiz suggests looking for a certified office ergonomics evaluator or board-certified practitioner of professional ergonomics.

To be covered by insurance, most evaluations require a doctors referral, says Hilker. Insurance typically covers some of the costs, but most people end up paying a portion [out of pocket], she says. Many corporate human resources departments will provide these services to their employees, Ruiz adds.

Your seated posture affects the positioning of your whole body. We can observe an increase in the stress on involved joints, such as the elbows, hands, knees, and feet when people sit in awkward positions, says Ruiz.

A comfortable chair is essential.Your workstation chair should:

Position your monitor directly in front of your face, with the top of the screen at or slightly below eye level. It should be about an arms length from you and directly behind your keyboard. (You may need to lower the monitor an inch or two if you wear bifocals).

Hilker says her psoriatic arthritis patients often say they struggle to find a comfortable position on a laptop. I often recommend getting a separate wireless keyboard in this case, she says. You can also buy an adjustable ergonomic laptop stand or a docking station with a full-size monitor to raise the height of your screen.

Your keyboard should be at a height where your elbows sit at or slightly more than 90 degrees while your wrists remain straight. If your keyboard is too high, you may want to either raise the height of your chair or buy a keyboard tray thats adjustable for both height and tilt and large enough to fit your keyboard and mouse on the same level.

Both Ruiz and Hilker recommend using an ergonomic split keyboard. It places the forearms and wrists in a more neutral position, says Hilker. She suggests trying out a few options at the store to figure out which feels most comfortable to you.

A keyboard rest may or may not keep your wrists in a more neutral position and prevent you from leaning your wrists on the edge of your desk. Just avoid mouse pads; Ruiz says theyre not great for your wrists and hands.

Once the rest of your body is in the correct position, check your feet: They should always remain firmly planted on the floor.

If your feet dont reach the ground when your chair is properly adjusted to your desk and computer equipment, place a footrest, small stool, or stack of books under your feet, suggests Ruiz.

Select a mouse that ensures your palm isnt completely flat, to avoid pressure on your wrist, suggests Ruiz. A vertical mouse (or any other mouse) that puts the hand in a slightly tilted position is a good bet.

It may also be easier for you to use a track pad instead of a mouse, as long as it reduces the stress in your hand and wrist. If you work in design, for example, where you have to constantly use a mouse, a trackpad can be a great option. If not, an ergonomic mouse can be used, says Ruiz. Some trackpads can be regulated to decrease the amount of pressure needed to activate and scroll, which can be helpful if joints are painful, adds Hilker.

Avoid any trackball mouse, Ruiz adds, since they tend to require too much motion in your thumb and fingers.

Keep objects you use a lot, such as your phone or stapler, within arms reach. If you cant comfortably reach something when youre sitting, stand up to get it.

Several other arthritis-approved assistive devices can reduce strain on the joints and help improve your symptoms and work performance, says Ruiz, including:

If you use the phone a lot for work especially if you have to take notes while talking use a headset or put your phone on speaker. This helps reduce stress in the neck and shoulders and keeps you from having to grip the phone in your hand or, worse, between your shoulder and ear.

Voice recognition apps and headsets can help decrease the amount of typing, says Hilker, which may also decrease pain.

Pay attention to your body throughout the day. If something feels tense or tight, get up, move, and stretch a bit.

Try to take a break and walk around your home or outside every 20 to 30 minutes. It doesnt have to be long: Two minutes is enough to reduce strain and get your blood flowing. Or Hilker suggests the 20-20-20 rule: Every 20 minutes, take a 20-second break and move 20 feet away from your workstation. Full-body movement is best, she says. Simply get up and walk around.

Add in a few gentle stretches that take just a minute or less. Focus on the areas that need it most: your neck, chest, lower back, forearms, and hips. Doing gentle shoulder rolls, neck movements, or low-back extensions can help reduce stiffness related to prolonged postures or repetitive motions, says Ruiz.

Sitting in awkward positions for long periods can lead to pain. For someone who has psoriatic arthritis, changing postures while working is very important to reduce stress to joints, muscles, ligaments, and tendons that can potentially generate pain, says Ruiz. Switching between sitting for 40 minutes and standing for 20 minutes is ideal, she says.

Sit-to-stand workstations are an excellent alternative to promote movement, adds Hilker.

Listen to your body, says Ruiz. Aim for comfort as much as possible, and plan ahead for rest periods during busy workdays.

Its also essential to keep work-related stress in check. Increased stress has been linked to increased pain level perception, says Ruiz. She recommends finding time for mindfulness activities, such as meditation, relaxation, and deep breathing exercises, during your day.

Continued here:
11 Ways to Make Your Home Office Psoriatic Arthritis Friendly - Everyday Health

In a study published in the National Library of Health, dermatology and diet was investigated.

The study noted: For decades, it was thought that many common dermatological conditions had no relationship to diet. Studies from recent years, however, have made it clear that diet may influence outcome.

In some cases, dietary interventions may influence the course of the skin disease, as in acne. In others, dietary change may serve as one aspect of prevention, such as in skin cancer and aging of the skin.

In others, dermatological disease may be linked to systemic disease, and dietary changes may affect health outcomes, as in psoriasis.

Numerous studies have found that a diet rich in fruits and vegetables reduces the risk of cancer.

Rhytids, sagging of skin, and loss of elasticity are all related to changes in the collagen and elastic fibres of the skin, which are themselves impacted by diet. Ingestion of sugar, in particular, can accelerate these signs of ageing, as it promotes cross-linking of collagen fibres.

The study concluded that dietary interventions have traditionally been an under appreciated aspect of dermatological therapy.

Recent research, however, has found a significant association between diet and some dermatological diseases.

See the article here:
Skin health: The best and worst foods for acne, psoriasis and skin disease - Express

It may seem like time is standing still right now, but we assure you fall has arrived. And, as usual, its brought with it a whole new set of skincare priorities as the weather shifts in many parts of the country. With the air becoming drier, temperatures falling, and winds picking up in some areas, a few small changes to your regimen can help keep your skin happy all season long. Below, three trickiest ways autumn can impact chronic skin conditions, plus how to combat them.

As the weather cools, irritation can go up, which means you might get flares of certain skin conditions. Joshua Zeichner, M.D., a board-certified dermatologist in NYC and associate professor of dermatology at the Mount Sinai Hospital says it makes sense: When the skin barrier becomes disrupted, it is more likely to become inflamed. That means dermatologists offices are flooded with complaints of psoriasis, eczema, and the like when the leaves start to turn. Here, the most common conditions that flare in the fall.

Psoriasis. This itch-inducing condition characterized by tale-tell plaques is normally better in the summer because of all the UV rays from natural sunlight, explains Sharleen St. Surin-Lord, M.D., an assistant professor of dermatology at Howard University in Washington, D.C. So when fall ushers in more indoor time, youve got to rely on those major psoriasis-curbing strategies like using moisturizer liberally throughout the day, firing up a humidifier at home, and talking with your doctor about adjusting your treatment regimen or adding ultraviolet light therapy.

Pityriasis rosea. Why this benign scaly pink rash can pop up more often on the trunk, upper legs, and arms this time of year: Pityriasis rosea is thought to be triggered by a viral infection, and since viruses are more common in the fall and winter, in some regions see more cases during that time, says Hayley Goldbach, M.D., a board-certified dermatologist and dermatologic surgeon at Brown University in Providence, RI. Home remedies include oatmeal baths and anti-itch lotions. While it is not a dangerous condition, talk to your doctor if the rash is itchy to see if medications can help with the discomfort.

Hives. Fall allergy season brings the increased risk of hives as you come in contact with itch-triggering fall staples like wool fabrics and ragweed pollen. If you get them once, an over-the-counter antihistamine will help, but if they happen frequently, Dr. Surin-Lord says to make an appointment with your derm for an Rx.

Eczema. Blame the dry fall air and scratchy scarves and sweaters for eczema flares. To help keep them at bay, look for soft cotton fabrics. And Dr. Surin-Lord recommends moisturizing with a hydrator featuring ceramides, which she calls the cement that holds the skin cells intact to keep moisture in. One of her go-tos is Eucerin Eczema Care, $9.50, cvs.com. And if you have an episode that doesnt clear, dont sufferhead to your dermatologist to discuss your prescription options.

The combination of falls crisp, brisk edge, blustery winds, and dry indoor heater air can do a number on your skin. Explains Dr. Zeichner, Cold weather and low humidity put a strain on the skin, stripping essential oils needed to maintain hydration. This translates to microscopic cracks in the outer layer, with loss of hydration, dryness, and inflammation. Ouch. Heres how to prevent that from happening, especially if you have psoriasis.

Moisturize intelligently. Cool, dry air calls for richer moisturizer formulasespecially in the face of irritating masks that many of us wear for protection against COVID-19. As the weather gets less humid, it will be especially important to keep your skin moisturized underneath it, says Dr. Goldbach. That means switching to a heavier nighttime moisturizer before bed to help restore the skin barrier while you sleep. But for those who need even more of an assist, Dr. Zeichner recommends putting a hydrating serum on before your hydrating cream, which will add another boost of moisture. Think of it as layering like you would with clothes. One to try: Isdinceutics Hyaluronic Booster, $39, isdn.com.

Prepare for wind. Fall in much of the northern U.S. is known for its blustery days, which can wreak havoc. In fact, one study in the Journal of Society of Cosmetic Chemists of Japan showed that not only does wind exposure decrease hydration but it also slows the replacement of the sebum level after. And on exceptionally windy days, theres the chance of windburn, a sunburn-like condition caused by a combination of dry air, wind friction, and UV exposure.

What to do? Dr. Zeichner says, My best recommendation is to apply a moisturizer right before going outsidethink of it as your base layer. Physical protection from the environment is helpful too, be it a scarf or even your face maskboth will prevent wind from directly irritating the skin. However, make sure to avoid scratchy fabrics like wool, which can not only be rough on skin but can trigger a flare-up of chronic conditions like eczema and psoriasis.

Try a humidifier. One of the things doctors stress for chronic skin diseases: preventing dryness before it starts. Enter a humidifier which adds moisture to the air, helping to head off winter irritation. The gadgets, according to Dr. Zeichner, can be used all year long if needed, but I typically recommend using one starting in the fall when the temperature starts to drop.

His advice: Stick to a cool-mist humidifier, like Honeywell Cool Moisture Germ-Free Humidifier HCM-350, $62, walmart.com. They are as effective as hot steam ones but are safer because they will not burn the skin if you get too close.

Remember balm. Your lips are very sensitivethey can be the first thing to show dryness or even vitamin deficiencies, says Dr. St. Surin-Lord. And with the dry air, that means you can not only be looking at parched lips but potentially an increase in chronic lip conditions like chelitis (caused by lip licking) or cold sores for those who get them, all thanks to your old friend irritation. Thats why its extra important to keep them hydrated as the seasons change. She recommends a lip balm with SPF 30 like Aquaphor Lip Repair, $4, ulta.com, for everyone but especially for anyone who likes to participate in outdoor fall activities like golf, fishing, and biking, as she reminds that lips are vulnerable to skin cancer.

Take care of hands. Parched palms and fingers are always a fall worry, but now with all the extra hand-washing that should be happening across the board, Dr. Goldbach explains that they tend to get dryer than other parts of the body because they are chronically exposed to environmental trauma. That means gloves will help when you leave the house by offering protection. And remember to reach for your favorite hand cream immediately after every washing, which, according to a study in BMC Dermatology, significantly decreases skin roughness after repeated sudsing sessions.

Dont forget the rest. The skin on your body needs a little extra love in the fall, too. Dr. St. Surin-Lord says its all about the formula you use. Lotions are light and good enough to use during the summer and late spring, but during the colder months, I recommend creams and even ointments for extra dry skin. Experiencing flakes? She recommends a moisturizer with an alpha hydroxy acid to add a bit of exfoliation for those dead skin cells. Her pick for all skin types (including reactive chronic conditions like psoriasis): CeraVe Psoriasis Moisturizing Cream With Salicylic acid , $26, cvs.com (although she notes that sal acid is a derivative of aspirin for those who are allergic).

Many people pack away the sunscreen when summer ends, but UV rays in the fall and winter can be just as damaging as they are in the warmer months. Even when the sun doesnt feel warm, it can damage your skin, upping the chances of melanoma and premature aging, even on cloudy days. Heres how to stay sun-smart all season.

Try a physical blocker. In 2019, the FDA suggested more research needs to be done into the impact of chemical sunscreens like oxybenzone when absorbed into the bloodstream. In the meantime, many dermatologists like Dr. St. Surin-Lord recommend mineral sunscreensespecially for those with sensitive skin. Dr. Zeichner agrees and points out that its also a great chance to get in some high-quality skincare ingredients to help replace any of that summer glow you might be missing right now. His pick: Ghost Democracy's Invisible Lightweight Daily Face Sunscreen SPF 33, which, he explains, contains niacinamide, which helps with tone and texture, and turmeric and artichoke leaf extracts, which are rich in antioxidants.

Check the expiration date. Sunscreen formulas have a shelf life of three years, and it can be easy to forget exactly when you acquired each bottle. Thats why at the change of every season Dr. St. Surin-Lord reminds her patients to check the expiration date to make sure they havent gone past the point in which the ingredients are at their full strength. What an awful experience it would be to mow the lawn, garden, or hang out in the park thinking youre safe with expired sunscreen on!

Follow the rules. You know how you know to apply sunscreen 30 minutes before heading outside and then reapplying every two hours in the summer? Dr. St. Surin-Lord insists the same goes for the winter. Since the sun isnt quite top of mind as it is in the summer, it can be easy to forget!

Beware the glare. Late in the season as snow starts to fall in some parts of the country, theres an extra element to toss into your sun-protection consideration: bounce back. If you are shoveling snow or skiing, you should wear sunscreen as the sun reflects on the snow and to your skin, causing sunburns, says Dr. St. Surin-Lord. That, she insists, is a job for SPF 50.

See the original post here:
How to Switch Over Your Skincare Routine for Fall and Winter - HealthCentral.com

CARLSBAD, Calif.--(BUSINESS WIRE)--Ra Medical Systems, Inc. (NYSE: RMED), a medical device company focused on commercializing excimer laser systems to treat vascular and dermatological diseases, announces it will feature the Pharos excimer laser at the New Frontiers in Cosmetic Medicine & Medical Dermatology Symposium 2020 Virtual Meeting being held November 21, 2020.

We are delighted to showcase our Pharos excimer laser at this conference, said Will McGuire, Ra Medical Systems CEO. Pharos provides topical treatment of common skin disorders including psoriasis, vitiligo, atopic dermatitis and leukoderma and is a lower cost and safe alternative to immunosuppressive agents. During the pandemic, Pharos may play a particularly valuable role for patients who may be otherwise immunocompromised.

About the New Frontiers in Cosmetic Medicine & Medical Dermatology Conference

New Frontiers in Cosmetic Medicine Symposium will deal with the latest developments in cosmetic dermatology, cosmetic medicine, and anti-aging medicine. It is designed for an audience of physicians, physician assistants, nurses and nurse practitioners who work under the direct supervision of dermatologists, facial plastic surgeons, oculoplastic surgeons, and plastic surgeons, and commonly assist with cosmetic surgery and medicine. More information is available at https://www.cosmeticfrontiers.com/.

About Ra Medical Systems

Ra Medical Systems commercializes excimer lasers and catheters for the treatment of vascular and dermatological diseases. In May 2017 the DABRA excimer laser system received FDA 510(k) clearance in the U.S. for crossing chronic total occlusions, or CTOs, in patients with symptomatic infrainguinal lower extremity vascular disease with an intended use for ablating a channel in occlusive peripheral vascular disease. The Pharos excimer laser system is FDA-cleared and is used as a tool in the treatment of psoriasis, vitiligo, atopic dermatitis and leukoderma. DABRA and Pharos are both based on Ra Medicals core excimer laser technology platform and deploy similar mechanisms of action. Ra Medical manufactures DABRA and Pharos excimer lasers and catheters in a 32,000-square-foot facility located in Carlsbad, Calif. The vertically integrated facility is ISO 13485 certified and is licensed by the State of California to manufacture sterile, single-use catheters in controlled environments.

Cautionary Note Regarding Forward Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements generally relate to future events or Ra Medicals future financial or operating performance. In some cases, you can identify forward-looking statements because they contain words such as may, will, should, expects, plans, anticipates, could, intends, target, projects, contemplates, believes, estimates, predicts, potential or continue or the negative of these words or other similar terms or expressions that concern Ra Medicals future expectations, strategy, plans or intentions. Forward-looking statements in this press release include, but are not limited to, statements regarding the timing and potential outcome of the DABRA atherectomy clinical study. Ra Medicals expectations and beliefs regarding these matters may not materialize, and actual results in future periods are subject to risks and uncertainties that could cause actual results to differ materially from those projected or implied by such forward-looking statements. The potential risks and uncertainties which contribute to the uncertain nature of these statements include, among others, challenges inherent in developing, manufacturing, launching, marketing, and selling new products; risks associated with acceptance of DABRA and Pharos and procedures performed using such devices by physicians, payors, and other third parties; development and acceptance of new products or product enhancements; clinical and statistical verification of the benefits achieved via the use of Ra Medicals products; the results from our clinical trials, which may not support intended indications or may require Ra Medical to conduct additional clinical trials or modify ongoing clinical trials; challenges related to commencement, patient enrollment, completion, and analysis of clinical trials; Ra Medicals ability to manage operating expenses; Ra Medicals ability to effectively manage inventory; Ra Medicals ability to recruit and retain management and key personnel; Ra Medicals need to comply with complex and evolving laws and regulations; intense and increasing competition and consolidation in Ra Medicals industry; the impact of rapid technological change; costs and adverse results in any ongoing or future legal proceedings; adverse outcome of regulatory inspections; and the other risks and uncertainties described in Ra Medicals news releases and filings with the Securities and Exchange Commission. Information on these and additional risks, uncertainties, and other information affecting Ra Medicals business and operating results is contained in Ra Medicals Annual Report on Form 10-K for the year ended December 31, 2020 and in its other filings with the Securities and Exchange Commission. The forward-looking statements in this press release are based on information available to Ra Medical as of the date hereof, and Ra Medical disclaims any obligation to update any forward-looking statements, except as required by law.

Ra Medical investors and others should note that we announce material information to the public about the company through a variety of means, including our website (www.ramed.com), our investor relations website (https://ir.ramed.com/), press releases, SEC filings, and public conference calls in order to achieve broad, non-exclusionary distribution of information to the public and to comply with our disclosure obligations under Regulation FD. We encourage our investors and others to monitor and review the information we make public in these locations as such information could be deemed to be material information. Please note that this list may be updated from time to time.

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Ra Medical Systems to Feature the Pharos Optimized Excimer Laser at the Virtual New Frontiers in Cosmetic Medicine & Medical Dermatology Symposium...