Daily Archives: June 21, 2020

funded study links endometriosis to DNA changes – National Institutes of Health

Posted: June 21, 2020 at 1:43 pm

News Release

Wednesday, June 17, 2020

DNA from uterine cells of women with endometriosis has different chemical modifications, compared to the DNA of women who do not have the condition, according to researchers funded by the National Institutes of Health. The changes involve DNA methylation the binding of compounds known as methyl groups to DNA which can alter gene activity. Moreover, the methylated DNA regions varied according to the stage, or severity, of endometriosis and responded differently to hormones involved in the menstrual cycle. Uterine responses to hormones influence pregnancy and other functions of uterine tissue.

The study was conducted by Linda C. Giudice, M.D., Ph.D., and colleagues at the University of California, San Francisco. It appears in PLOS Genetics. The study was funded by NIHs Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

The findings raise the possibility that differences in methylation patterns could one day be used to diagnose endometriosis and develop customized treatment plans for patients, said Stuart B. Moss, Ph.D., of NICHDs Fertility and Infertility Branch.

Endometriosis is a disease in which tissue similar to the lining of the uterus grows in other places in the body, such as on the ovaries, fallopian tubes or the bowels and bladder. It affects from 5 to 10% of women in the United States. Its main symptoms include pain, especially during menstrual periods, and infertility. Endometriosis is classified into four stages, ranging from minimal (stage I) to severe (stage IV). The only definitive way to diagnose endometriosis is with a surgical procedure called a laparoscopy.

The researchers analyzed a type of cell known as an endometrial stromal fibroblast, which regulates cells in the lining of the uterus. They compared methylation across DNA regions and differences in gene functioning in cells from women who did not have endometriosis or any other gynecological disorders to those of women with stage I endometriosis and of women with stage IV endometriosis. They also observed methylation patterns and gene functioning after the cells were exposed to estradiol (a form of estrogen) alone, progesterone alone, and to a combination of the two hormones to mimic changes in the levels of these hormones that occur during the menstrual cycle.

DNA methylation patterns and gene functioning differed among all groups of cells before exposure to the hormones, with exposure to each individual hormone, and to the combination of the two. The differences in methylation and gene functioning between stage I and stage IV endometrial cells could mean that the two may be distinct subtypes of endometriosis, rather than different degrees of the condition, Dr. Giudice added.

The data indicate that the proper interactions of hormones and DNA methylation are critical in normal uterine function, said the studys lead author, Sahar Houshdaran, Ph.D., University of California, San Francisco. The changes in these interactions that weve seen could play a role in the infertility that often accompanies endometriosis.

About the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD): NICHD leads research and training to understand human development, improve reproductive health, enhance the lives of children and adolescents, and optimize abilities for all. For more information, visit https://www.nichd.nih.gov.

About the National Institutes of Health (NIH):NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov.

NIHTurning Discovery Into Health

Houshdaran S, et al. Steroid hormones regulate genome-wide epigenetic programming and gene transcription in human endometrial cells with marked aberrancies in endometriosis.PLOS Genetics. 2020.

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Pak-origin 26/11 conspirator Tahawwur Rana arrested in US, likely to be extradited to India – DNA India

Posted: at 1:43 pm

Tahawwur Rana, the conspirator of the 26/11 attacks in Mumbai has been rearrested in the US and is likely to be extradited to India over his involvement in the 2008 terror attacks in which 166 people were killed.

The 59-year-old Pakistani-born Canadian was serving a 14-year-sentence and he was allowed early release from the prison after he told a US court that he has tested positive for COVID-19. However, he never made it out of prison.

Following an extradition request by India, where he has been declared a fugitive, he was rearrested on June 10.

Assistant US Attorney John J Lulejian informed the court that as per the bilateral Extradition Treaty signed in 1997, the government of India has requested the arrest and detention of Rana with a view towards his extradition, news agency PTI reported.

Rana is being prosecuted in India for a number of offences, including the conspiracy to commit murder, in violation of Sections 120B and 302, and murder in violation of Section 302 of the Indian Penal Code (IPC), Lulejian told the court.

As per the federal prosecutors, Rana participated in a conspiracy with his childhood friend David Coleman Headley, also known as 'Daood Gilani', and others to assist Pakistani terrorist organisations Lashkar-e-Taiba (LeT) and Harakat ul-Jihad-e-Islami, to carry out attacks in Mumbai.

He has been charged "with murder and murder conspiracy in India, according to court documents", he had however been cleared of the more serious charge of "providing support for the attacks in Mumbai."

"Rana's lawyer said at trial that he had been duped by his high school buddy, Headley, an admitted terrorist who plotted the Mumbai attacks. The defence called Headley, the government's chief witness who testified to avoid the death penalty, a habitual liar and manipulator," according to an article in The Washington Post.

He is also accused of assisting in a plot to carry out an attack on a Danish newspaper that printed cartoons on Prophet Muhammad in 2005. The plot could never be carried out.

(With ANI inputs)

Tahawwur Rana was first arrested in Chicago in 2009. He went to trial in the US District court for the Northern District of Illinois where Headley testified for the prosecution.

He was convicted of one count of conspiracy to provide material support to terrorism in Denmark and one count was of providing material support to Lashkar.

Thereafter, US District Judge for the Northern District of Illinois, Harry D Leinenweber, sentenced him to a 168-month prison term.

Another charge on Rana is a conspiracy to forge documents for the purpose of cheating and conspiracy to use as genuine a forged document or electronic record.

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How DNA tests can set you on the path to healthy skin and hair – Telegraph.co.uk

Posted: at 1:43 pm

As with illness, prevention is always better than cure when it comes to skincare which is why we use shave cream to minimise razor burn and sunscreen to prevent wrinkles.

The ultimate preventative action, though, comes from understanding how your DNA affects your skin and hair so you can tailor your grooming regime to accommodate those quirks.

A CircleDNA test for example, revealed I have a high genetic risk of hyperpigmentation (had I known this years ago, Id have been extra-vigilant about sun protection) and a greater need for antioxidants molecules essential for healthy skin and hair.

Meanwhile, 23andMes test can tell you among other things whether youre prone to dandruff and bald spots. They may sound gimmicky but tools like these take some of the guesswork out of good grooming and could save you money in the long run. Great if, like me, thriftiness is in your genes.

DNA Genetic Analyses, 520, Lisa Franklin

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Watch Solar Eclipse 2020: Here are the Dos and Don’ts to witness the grahan – DNA India

Posted: at 1:43 pm

Solar Eclipse on June 21: The entire world is bracing itself for the annular solar eclipse, which is popularly known as the "ring of fire" eclipse.

You can witness the Solar Eclipse or Surya Grahan 2020 on June 21 (Sunday).

The eclipse will begin at 9.15 am and it will end at 3.04 pm.

It will be the first solar eclipse of this year takes place on the summer solstice, which is the longest day in the Northern Hemisphere. While people living along the path annular eclipse passing through Anupgarh, Suratgarh, Sirsa, Jakhal, Kurukshetra, Yamunanagar, Dehradun, Tapowan and Joshimath will be able to see the annular phase, people in rest of India can witness a partial eclipse, said the Ministry of Science and Technology.

When Moon comes between the Sun and Earth, the shadow falls on the surface of the Earth. The Sun is entirely covered by the Moon for a brief period. Those places that are engulfed by the dark, dense umbral shadow of the Moon experience the total solar eclipse.

"Annular solar eclipse is a particular case of the total solar eclipse. Like the total solar eclipse, the Moon is aligned with the Sun. However, on that day, the apparent size of the Moon happens to be a wee smaller than the Sun. Hence the Moon covers the central part of the Sun, and the rim of the Sun appear like a 'ring of fire' in the sky for a very brief moment," Samir Dhurde of The Inter-University Centre for Astronomy and Astrophysics, Pune explained to ANI.

People living in Northern India will be able to witness the 'ring of fire' for 38 seconds. While, other parts of India will be able to see the total solar eclipse 2020 for around 82 seconds.

Apart from India, It can be witnessed in most parts of Africa, the Middle East and Asia.

Here are certain Dos and Donts we need to keep in mind while watching the eclipse.

1. Proper eye protection is needed to watch the solar eclipse as looking for a long period of time at the sun may damage your eyes.

2. A special solar filter on the lens is required to capture the eclipse.

3. If you are living in one of those countries where the solar eclipse cannot be sighted, it can also be watched virtually.

4. Don't look at the sun directly.

5. Don't look at the reflection of the sun in the water.

6. Ordinary sunglassed should not be used to witness the eclipse.

This year's annual solar eclipse will be particularly special as majority of the people will be couped up inside their homes amidst the coronavirus pandemic. Normally, people travel a great distance to observe the solar eclipse.

(With ANI inputs)

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In Switzerland neuroscientists raised a copy of the brain with the DNA of Neanderthals – The Times Hub

Posted: at 1:43 pm

Neuroscientists from the Institute of molecular ophthalmology at Basel in Switzerland from stem cells with the DNA of Neanderthals raised miniature replicas of the brain. The experiments helped to determine the cause of the disappearance of this branch of the ancient people.

Experts have created a mini-copy of the on interspersed with the DNA of Homo neanderthalensis. The inhabitants of the Nordic countries, the researchers note, you can often find some variation of Neanderthal genes. This circumstance allows to assert, that we are talking about the gene structures, copies of which are inherited from those ancient people. Grayson camp, a paleontologist, spoke about the work of the research group. Neuroscientists were interested in the DNA related to hair and skin color. It is possible to examine the impact of segments of the genetic structures in the entire chain of the development of the human brain.

Neanderthals in contact with the ancient ancestors of the people left in human DNA, about 4% of their genes. For this reason, the tribes were able to adapt to survive in the North of the European continent. Scientists have concluded that Homo neanderthalensis could disappear because of genetic degeneration, not competing with CRO-magnon, as previously believed in the scientific world.

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Atletico Madrid vs Real Valladolid, La Liga: Live streaming, teams, Dream11, time in India (IST) & where to – DNA India

Posted: at 1:43 pm

Atletico Madrid welcome Real Valladolid for their upcoming La Liga 2019-20 game.

Atletico Madrid will be eyeing to continue their winning run in todays game as they are 4th with 49 points. Real Valladolid, on the other side, with 33 points from 29 outings, are 13th on the league standings.

Where and when is theAtletico Madrid vs Real Valladolid, La Ligamatch being played?

TheAtletico Madrid vs Real Valladolid, La Ligamatch will be played on June 21, 2020, at Wanda Metropolitano Stadium.

What time does theAtletico Madrid vs Real Valladolid, La Ligamatch begin?

TheAtletico Madrid vs Real Valladolid, La Liga match will begin at 01:30 AM IST.

Where to watch Atletico Madrid vs Real Valladolid, La Liga live in India (TV channels)?

Unfortunately, theAtletico Madrid vs Real Valladolid, La Ligalive telecast won't be telecasted in India.

How and where to watch onlineAtletico Madrid vs Real Valladolid, La Liga live streaming?

TheAtletico Madrid vs Real Valladolid,La Ligalive telecast will be available online on Facebook to watch in India.

Atletico Madrid: Oblak; Trippier, Savic, Gimenez, Lodi; Correa, Thomas, Saul, Koke; Morata, Felix

Real Valladolid: Masip; Moyano, Fernandez, Salisu, Martinez; Plano, Alcaraz, Michel, Suarez; Unal, Guardiola

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Max Planck Created Quantum Theory and Laid a New Foundation for Physics – Interesting Engineering

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At the base of modern physics is something called quantum theory. It explains the behavior of energy and matter on different atomic levels - atomic and subatomic. Quantum theory encompasses the working of the realms of physics commonly referred to as quantum physics and quantum mechanics and it offers up a rather interesting look into the foundations of modern physics.

Quantum theory was first presented to the general public in the year 1900, by a physicist named Max Planck. He presented the theory to the German Physical Society, specifically by presenting the results of an experiment he had done looking into the color of radiation from glowing bodies (not human bodies, physical bodies).

In the experiment, he found that if he assumed that energy existed in individual units similar to matter, that he would find the answer to the original question posed in his experiment. Thinking of energy in this way was new and allowed the energy to be easily quantified. These units of energy that he was able to quantify were named quanta by Planck in his writings about the experiment and subsequent mathematical equations.

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The equation that formed the beginnings of quantum theory demonstrated that at certain temperature levels, the energy that was let off from a glowing body would exist in different areas of the spectrum of color, or wavelength. Planck initially imagined that his discovery of quanta would set in motion the creation of a new theory, but what actually ended up happening was that it completely rewrote humanity's understanding of the laws of nature.

In 1918, Planck won the Nobel Prize for his discovery and research on quanta. It is important to note though, that while Planck's research began the foundation of modern quantum theory, tens to hundreds of other scientists worked in the years prior to set Planck up to make this discovery just at the point that he did. Taking a closer look at the timeline, we can see how the theory progressed after the discovery.

1900: Planck makes the initial discovery, or rather assumption, that energy was made of units called quanta.

1905: Albert Einstein theorizes that energy and radiation could be quantified in the same way that Planck had theorized of quanta.

1924:Louis de Brogliefirst proposed that there was no difference between energy and particles in his theory of wave-particle duality, also demonstrated in the famous double-slit experiment.

1927: A scientist by the name of Werner Heisenberg theorized that the measurement of two complementary values at the same time, such as the position and momentum of a given subatomic particle, would be impossible. This stands starkly in contrast to traditional physics and became known as the uncertainty principle.

Now that we've taken a closer look at the timeline of quantum theory development, let's take a closer look at who exactly Max Planck was.

Born in April of 1858, Max Karl Ernst Ludwig Planck (quite the name) was a theoretical physicist who was the originator of quantum theory, which, as we've discussed, afforded him the Nobel Prize in Physics in 1918. During his lifetime he made major contributions to the field of theoretical physics but the quantum theory remains his largest accomplishment.

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Quantum theory at the hands of Planck completely revolutionized our understanding and conceptualization of quantum particles and processes. It could be equated in gravity of the theory of Alber Einstein's theory of relativity that changed our understanding of space and time.

Both quantum theory and the theory of relativity exemplify the foundations of all of the 1900s physics, forcing researchers to rethink how they approach the world around them.

Planck passed away at the age of 89 years-old in 1947 in Germany.

The main methods of interpreting quantum theory are known as the Copenhagen interpretation and the many-worlds theory. The Copenhagen theory proposes that a particle is whatever it is measured to be. In other words, if you measure a particle as a wave, it's a wave. However, it also states that you can't assume that it has any specific properties or that it exists until you measure it. It's an off-the-cuff way of insisting that physical reality doesn't actually exist until you observe it. This leads way to the idea of superposition, which means that any given particle or object can be in any number of potential places at once during the period that we don't know its position, or aren't observing it.

The famous thought experiment of Schrodinger's Cat is the perfect exemplification of this interpretation of the quantum theory.

The many-worlds theory or multiverse theory. This states that as soon as the potential for an object to exist occurs, the universe splits into a series of parallel universes where both states of that object exist. This theory is the basis of TV shows like Rick and Morty or other popular science fiction stories, but at the end of the day, it's a very real interpretation of the quantum theory.

Both Stephen Hawking and Richard Feynman expressed that they preferred the multiverse theory style of interpretation.

At the end of the day, quantum theory and Planck's research have drastically influenced the work of physicists and researchers over the last 100 years. The implications of quantum theory can be a little mind-boggling though, even causing Planck himself to balk at them during his time. The foundational principles of the theory, however, continue to be repeated and proven through subsequent experimentation. Physics in many ways still will be fleshed out in the next century, but its foundation of quantum theory laid by Max Planck is likely here to stay.

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Do we need a ‘Quantum Generation’? | TheHill – The Hill

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Driving Route 66 requires no specialized training. Steering wheel, pedals, lights, mirror controls they are all familiar concepts, each one a well-established automobile technology. If youve driven one car, youve more or less driven them all. Call it drivers intuition.

However, despite the publics growing awareness of quantum technology, a corresponding intuition is rare, even among experts in the field. With quantum intuition, one could differentiate between quantum and classical worlds at the most basic level without deliberation.

For most of us, stuck with our classical minds, quantum intuition is difficult due to the counterintuitive nature of the quantum world. Concepts like entanglement and superposition can be challenging, since there is no obvious mapping of the bizarre quantum world to everyday life.

Developing our quantum minds

Most of us have technological intuition, like the ability to drive an unfamiliar car or use a new computer program. Unhindered by philosophical obstacles, it allows children to program a TV remote or master a smartphone much faster than their parents. Thats because kids today have been born and raised surrounded by technology built upon classical computers and have developed an intuition for them.

With quantum computers only now emerging, such early development is lacking. Consider, for example, light. While familiar in the macroscopic world, its quantum properties are odd. Sometimes it behaves like a wave, sometimes like a particle. Think of quantum particles that can pass, or tunnel, through energy barriers. Or imagine entangled particles, which influence each other even if separated by a large distance. There are also mind-boggling interpretations of quantum mechanics that drive ongoing and vigorous debates among specialists, such as theories of multiple universes or theories in which the future influences the past.

The legendary spookiness of quantum mechanics which so bothered Albert Einstein is born from similar examples, and the frustrations expressed by Einstein, Richard Feynman or Erwin Schrdinger are as painful today as they were a century ago.

As the quantum technological revolution changes the world, it must first move out from laboratories and into proverbial garages. To get there requires a quantum education at an early stage, an effort to tunnel through the barrier of quantum weirdness and kick-start a quantum generation of young people who can consider entanglement without being spooked, like we are, and instead set up those garages and launch completely new approaches to quantum technology.

From quantum intuition to quantum workforce

We are not yet ready for that transition. Mastering intuition requires a solid quantum education, one that crosses disciplines and fuses physics, computer science, engineering, mathematics and materials research in nearly equal parts.

Such an education must include focused training at the elementary, middle and high school levels, as well as informal education at museums and unconventional approaches like merging art into quantum education.

How do we get there? With much to do, the United States is not sitting idle. For example, several first steps emerged from a recent collaborative effort from the National Science Foundation (NSF) and the White House Office of Science and Technology Policy that brought together cross-disciplinary specialists to develop core resources for inspiring quantum information science learners. One outcome, a necessary minimum list of nine key concepts with narratives developed by subject-matter experts, is helping shape the nations approach to early education, tackling such concepts as qubits, quantum computers and entanglement, just to name a few.

Industry is also getting involved. As students further develop their careers, the convergent efforts of industry, academia and government will be vital, as will early introductions to industrial settings. One initial effort, known as the TRIPLETS program, was initiated by NSF and co-sponsored by industrial partners such as IBM, Google, Raytheon, Montana Instruments and many others, including several Department of Energy National Laboratories. This approach allows students to collaborate with both an industrial advisor and an academic investigator, forming a triplet that introduces fundamental research and industrial culture well before graduation.

A continuing national investment

Fundamental research generates high quality educational experiences, which will lead to quantum intuition, and this cultural and technological shift requires investment.

The ambitious all-of-government approach known as Industries of the Future includes a plan to increase federal investments in five key industries to $10 billion per year by fiscal year 2025. In addition to quantum information science, the targeted industries include artificial intelligence, 5G technologies and advanced communications, biotechnology and advanced manufacturing, with quantum technologies further integrating across the other fields.

This plan builds upon the National Quantum Initiative Act, established in 2018, with both efforts calling for the development of a future quantum workforce and a strong focus on education.

However, implementation will require educators, academics, industry, and government agencies working together to create the policies and practices that enable young people today to develop the quantum intuition needed for the future.

Armed with intuition, the quantum generation will come.

Tomasz Durakiewicz is program director for Condensed Matter Physics at the National Science Foundation, Division of Materials Research, and since February 2019 has served as staff associate, Office of the Assistant Director, in the agency's Directorate for Mathematical and Physical Sciences. Durakiewicz has co-authored more than 170 peer-reviewed publications, more than 210 conference abstracts and six patents, and he has presented more than 60 invited talks. For more than a decade prior to his service at NSF, Durakiewicz was a materials researcher at the Department of Energy's Los Alamos National Laboratory.

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‘Everything was centered around Sara, he was lost’: Abhishek Kapoor on Sushant Singh Rajput after ‘Kedarnath’ – DNA India

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Sushant Singh Rajput died by suicide at the age of 34 on June 14 and since then there have been a lot of theories floating around why he took such a drastic step. Filmmaker Abhishek Kapoor who has worked with Sushant in debut film 'Kai Po Che' and later in 'Kedarnath', in a recent interview said that he was a "troubled man, whose mind was systematically dismantled by the industry."

As per reports on BollywoodLife, Abhishek said, "Its a systematic dismantling of a fragile mind. Sushant was brilliant, he was an engineer, he was into astrophysics and quantum physics. But because we couldnt box him into stereotypes we called him off. He was off, just off your radar. Theres this thing that if youre not like us then you cant be with us. There are so many camps that if youre not part of a camp, even if youre in the middle of a room, you will be ignored. It is true, especially for actors. I, as a filmmaker, can isolate myself. I can warn a young actor but he cannot see it at the time because the lights are so bright. You lose yourself."

The director further added how Sushant was trobled while shooting for 'Kedarnath' but when it was time to shoot he was 100% in the scene. For the uninformed, 'Kedarnath' was the debut film of actress Sara Ali Khan. The filmmaker said that Sushant felt that all the media attention had diverted towards her and he became reclusive.

"I had not spoken to him for about a year and a half. There were times, you talk and then youd go away to do a film. He must have changed his number 50 times and I remember when Kedarnath was coming out, the media had just slammed it. I dont know what happened, he could see that he was not getting the kind of love because everything was centered around Sara at that time. He was just kind of lost. When the film released and it did really well, I sent him a message saying, 'Bro I have been trying to reach you, Im not sure if you are upset, or just busy, but call me so we can chat. We made a super film together, again. If we are not going to celebrate it then what the hell are we going to celebrate in life? So please call me, I love you' to which he didn't respond. He didnt respond to me on his birthday. I said to myself just let it be. I could see he was not in a good place but you cannot cross a line," he stated.

Abhishek was present at Sushant's funeral along with his wife. He was cremated at Mumbais Vile Parle crematorium on Monday.

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RHOBH: What’s with Denise Richards Husband Aaron Phypers? – Screen Rant

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Fans have been clamoring for more quantum physics on the show and it's finally here, in the guise of Walker Texas Ranger AKA Denise Richards husband.

A collective exhale of relief was released from the fandom earlier this season on The Real Housewives of Beverly Hills, when the franchise finally decided to nix dinner topics like you fat-shamed my dogs caftan to finally unpack the theory of quantum physics and neurophysiology and its relation to molecular healing from vibrational frequencies (its about time). To whom holds the honor of elevating dinner discussion from tarot readings to highly classified government conspiracies? Sir Aaron Phypers / Aaron Cameron / Mr. Denise Richards, AKA "D-packin Chopra."

A wellness human tank, by way of Walker Texas Ranger, the only vibrations audiences were attuned to last season were the ones emitting from below Aarons Bootbarn belt buckle. The size of the rookie house husbands womb broom fell out of Ms. Richardss mouth more frequently than Kyle has a panic attack on a domestic flight.

Related:VPR, Southern Charm, RHOD & The Challenge Firings Reveal PR Apologies

But this season Aaron ignored all warning signs from the House Husbands Handbook to Navigating Reality TV Fooferah and went all in. Based a previous episode, An Hour of Bouncy Bonding with Lisa Rinna,' Phypers was intent on speaking The Truth, if The Truth was a riddle from a rotted fortune cookie. Attempting to break up a fight, Aaron interjected: When people win, also people engage because they want to see how people won ...keep that in mind ladies.That they did, as you could see the cogs turn behind their collective eyes. What? Was this the prologue of The Shart of War? The rest of his diatribe was equally confusing, attempting to drop truth bombs from space. Its pretty hard to be condescending when the words never ascend. Much like Gigi Goode of Drag Race, this was not an Aha moment.

That said, Watching Aaron argue is exhilarating. Every jab is like a mad-libs of bro-isms, or like watching a straight guy solve an "instant shad" Rubik's cube. Hes above their frequency, apparently. So what frequency is he on? Wed always gotten curious nuggets dropped every now and then as to what exactly his job is. Then, of course, the latest in the Dinner Party From Hell franchise an episode earlier (in which Phypers and Denise seemed to be on high alert as to whether the government was listening - seriously), where he went on a heavily edited lunacy rant on quantum theory while Mauricio counted the vast black hole of minutes fly by before he could get his jush again.

It was insane. Definitely up there in the Museum of Errant House Husbands collection of Antiquities, alongside The Career of one Slade Smiley, A Night in Prison at the Apollo, and Simon McCord's red leather pants. Phypers business apparently is called the "Q360 Club," which according to their website is a "state-of-the-art healing center designed to foster optimal health in mind-body-spirit." Q360 uses sound therapy and a "holistic approach to harness a wide range of energy fields to accelerate healing and amplify healing capabilities. Just in case youre wondering, yes the scientific community disowns it, and yes he thinks big pharma is out to kill him, at best its "Big Parma" a heavy set Italian Maitre d who wants his look back.

Whatever, either way, we have this on our TV sets, and were glad to see it. The more alarming moments, however, are his chilling aggressions towards Denise both at this dinner and in the latest episode, when the pair left hand in hand and he muttered under his breath: "Don't tell me what to say, I'm going to crush you f*cking hand." Foreshadowing indeed, as the rest of the season is about to heat up once again for the couple when chaotic evil fan-favorite Brandi Glanville (who entered the franchise without a leg to stand on, literally) is back to do what she does best: hunt, kill, and destroy. The rumor? Brandi has secretly been in a sexual relationship with Denise outside of her marriage. In the real world: oh sure, maybe theyre in an open pansexual relationship with like-minded consenting adults, on Real Housewives: Escandalo!

Regardless, this information comes by way of Glanville Courier Pidgeon, meaning its carrying an avian bird virus intent on leveling 90210. As for The Richards, were strapped in and ready to burst, waiting to see how this turns out on the remaining season of The Real Housewives of Beverly Hills. In the meantime, some sage advice for Mr. Phypers, to quote Lisa Simpson: tis better to be thought the fool than to open ones mouth and remove all doubt.

Next:The Real Housewives: Worst Couples, Ranked

90 Day Fianc: Happily Ever After? Are Colt & Jess Still Together?

Marshall Lorenzo is a sketch comedy writer and performer living in Toronto. Originally from Auckland, New Zealand, he was the head writer of the multi Canadian Comedy Award-winning sketch troupe The Sketchersons, and a writer/performer in the 2019 Canadian Comedy Award-winning show Extravaganza Eleganza. He now writes for TV (the eyeballs and earholes) and the computer screen (just the eyeballs). He likes sitting down and vodka.

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