Daily Archives: August 1, 2017

North Korea FIRES submarine missile as WW3 fears reach fever pitch – Daily Star

Posted: August 1, 2017 at 6:27 pm

THE US has detected highly unusual North Korean submarine activity, just days after the rogue state conducted its second test of an intercontinental ballistic missile (ICBM).

The submarine was evidence of an ejection test, which examines a missiles cold-launch system.

A US defence official told CNN that unprecedented levels of submarine activity has been detected.

These include three "cold ejection" tests in July.

Getty

Since 2008, photographer Eric Lafforgue ventured to North Korea six times. Thanks to digital memory cards, he was able to save photos that was forbidden to take inside the segregated state

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Taking pictures in the DMZ is easy, but if you come too close to the soldiers, they stop you

An ejection test uses high-pressure steam to expel a missile from the launch tube before ignition to reduce the risk of damage to the vessel.

The latest test took place on land at Sinpo Naval Shipyard on Sunday.

Daily Star Online revealed the shocking consequences of war with North Korea.

While tourists are free to visit the secretive state as part of strictly controlled tour groups, they are told to never take photos of soldiers by their handlers. These images taken by photographer Eric Lafforgue show the truth behind North Korean military service: a life of hard physical labour with the perks of visits to the nation's capital

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Many soldiers are used as a labor force to compensate for the ineffective North Korean economy, so the army is not only about military organization.

North Korea who are said to have 70 submarines in its fleet also engaged in unusual deployment activity last month when a Romeo-class submarine travelled 100 kilometres out to sea off the coast of Japan.

The regimes newest vessel, the diesel powered Sinpo-class, is the only one believed to have ballistic missile launch capability.

A recent ICBM test showed North Korea was within range of Alaska though its missiles still couldn't reach the contiguous United States.

After the test, it emerged the US had passed up a chance to assassinate Kim Jong-un, having watched him at the launch site for more than an hour without attacking.

But the brush with death has done nothing to silence the leader, with North Korea now boasting that nuking the US and South Korea had become a "piece of cake".

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Ready for WW3? Russia moves 8000 troops and 50 planes as Putin braces for North Korea war – Daily Star

Posted: at 6:27 pm

VLADIMIR Putin is preparing 8,000 troops, 50 warplanes and 3,000 pieces of military kit for war amid fears the US may invade North Korea.

GETTY

Russia held the massive combat readiness check of its Eastern Military District as global tensions continue to flare over the North Korea crisis.

The huge military drill took place in Russias eastern Transbaikal region around 3,000km (1,300miles) from its border with North Korea.

Putin fears the US may launch military action against the communist state after it tested another intercontinental ballistic missile last week.

The international community reacted with fury to the test, with the US accusing Russia of bearing unique and special responsibility for North Korea.

Now it appears the Russian President is preparing his eastern military for a conflict in the event it kicks off on the Korean peninsula.

TASS

A look inside the powerful Russian Army.

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5 Russia's soldiers prepare Russia's air defence system S-400 Triumf launch vehicles on August 13, 2014 in Elektrostal, Russia.

Putin made a similar move earlier this year when he sent soldiers to Russias border with North Korea in anticipation of a bust-up.

In a statement, the Russian Defence Ministry said: During the combat readiness check, the personnel of one of the motor-rifle units of the combined-arms army deployed to the Transbaikal region marched for 150 kilometers and crossed the Onon River.

During the march, Mil Mi-24 attack helicopters covered military hardware.

North Korea has ignored that entirely and escalated the situation in a one-sided way.

In a phone conversation with Trump today, Japanese Prime Minister Shinzo Abe called on Russia to increase pressure on North Korea.

Speaking in Tokyo he said: "We have made consistent efforts to resolve the North Korean problem in a peaceful manner, but North Korea has ignored that entirely and escalated the situation in a one-sided way.

"The international community, starting with China and Russia, must take this obvious fact seriously and increase pressure."

AFP

Ghosts of the last time America went to war in Korea have been brought back to life through the work of a British electrician. The stunning pictures show ships lined up on the shore at the Battle of Inchon and troops boarding a plane ready for a drop behind enemy lines north of Pyongyang, Korea

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Relations between Moscow and Washington have frayed in recent weeks after the US slapped Russia with more sanctions.

In response, Russia has refused to rule out military action if Trump approves further sanctions.

To show off Russia's military might, Putin flaunted his sea power with a huge naval parade at the weekend.

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For children, it’s beyond psychedelics – The Hans India – The Hans India

Posted: at 6:26 pm

Academic compulsion and peer-pressure adding to the woes

Psychedelic drugs are not the only cause of concern, high school students and youngsters are addicted to things like cough syrups, glue and whiteners. Recently the governments focus has only been on drug peddlers and celebrities but, the real focus should begin at home and schools.

I have patients as young as seven-years-old, who are addicted to medications like cough syrup or stationary items. This is due to the complete lack of parental guidance, opines Dr Namita Singh, neuropsychologist at Apollo Hospitals.

Further, she said that if the child is prescribed a medication for a time, h/she continues to use the medicine even after that. Excessive use of such medications can lead to failure of vital organs, like the liver, she warns.

The schooling system is also to be blamed, she argues. Because of the hectic curriculum children are constantly under pressure and they opt for immediate relief from it.

I even tried to contact some schools to conduct an awareness session for high school students about sexual education and usage of drugs but, they didnt seem interested in this.

Educational institutions are only concerned about their syllabus but, they are hugely lacking in extracurricular activities like sports, dancing or anything creative for that matter, she adds.

Speaking about the psychological conditions of students she shares, A 13-year-old kid was recently brought to me by his mother because of his erratic behaviour and loss of appetite. His mother complained that he was always irritated and physically aggressive with his brother.

High pressure from schools drives children crazy. This is no way to live a life; at least parents should understand and allow their children to participate in other creative activities, she opines.

She also says that many parents are still unaware about their childrens addictions and weaknesses, and even if they do know about it, they are unwilling to bring their kid to a psychologist.

If education doesnt begin at home then these psychological conditions will haunt the individual in their adulthood as well. Many software employees are also facing these behavioural issues at an early age.

To get away from their day-to-day deadlines and work pressures they divulge into alcohol, smoking and drugs, opines the doctor.

By: Tera Sneha Reddy

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For children, it's beyond psychedelics - The Hans India - The Hans India

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Modern psychedelic science is reviving lost research and finding new cures – The Plaid Zebra (blog)

Posted: at 6:26 pm

The future is bright; its colours, sights and sounds more vibrant and steeped in a better understanding of our consciousness and its brought to you by the wonders of psychedelic science. It is a field of study with a storied history that is experiencing a renascence as countries around the world and their governments begin to open their minds.

For those who have experienced the wonders of psychedelics, the benefits they can offer are clear. Its easy to explain that elated sense of being and self to someone who is already an enthusiast, but for the rest of the world science is the key. That is why researchers in this field want to bring science and psychedelics together, as they once were, and in the past several years they have done just that.

Within the US the Multidisciplinary Association of Psychedelic Studies (MAPS) is on the verge of receiving FDA approval of its MDMA-assisted therapy for patients with PTSD.

A year ago MAPS wrapped up six trails conducted in the US, Israel, Switzerland and Canada in which treatment resistant PTSD was treated with MDMA inspired therapy.

Its proven to be an immensely effective form of treatment which is on track for wide-scale approval by 2021. The latest study, which included 107 participants, found that 66 percent of patients no longer qualified for PTSD after just two sessions. In their previousstudy that number was 83 percent.

The success of these trials has launched MAPS into the final phase of FDA approval in which they will continue their clinical trials as well as provide training for up to 100 therapists to be certified in administering MDMA-assisted therapy.

Brad Burge, Director of Strategic Communications for MAPS, insists that the FDA and even the DEA have been extremely cooperative with their studies. Hes seen a great reception for these alternative therapies from the scientific community and their patients and expects greater acceptance as the studies continue.

I think that the momentum is strong enough and the need for alternatives is great enough that any sort of counter marketing that big pharmaceuticals would do would probably only make what were doing more popular. Says Burge.

As with anything, there are also potential risks, but Burge notes that a large part of the governments acceptance of their studies has come from the careful procedures and practices theyve adopted. Safe storage, in house administration of drugs and most of all an openness in communication with the patient.

As far as any sort of addictive potential, Brad says, there is zero evidence that a couple of administrations of MDMA in a therapeutic setting will lead to any form of dependence.

Of the 107 patients that have been treated by MAPS, only a couple have sought out the substance outside of their scheduled therapies, those patients were compelled by the results MDMA provided yet they later admitted as Burge also insists that the therapy is a crucial element.

As a result of such studies, MDMA is likely to go the way of marijuana, in that its medicinal usefulness will eventually lead to widespread acceptance.

But one psychedelic which still has a long way to go in quelling the public stigma is ironically one which could also do a lot to ease peoples fears: LSD. Widely unknown to the public, the experience of LSD is often thought of as a hallucination-inducing brain-melter. Even film portrayals of acid trips have had a difficult time capturing the true experience.

Among those who have taken the substance, it is often thought to have a positive transformational effect in their lives, especially when as with MDMA it is administered properly and in a comfortable environment. Yet the difficulty in conveying the experience has made LSD one of the most feared drugs in the world.

Much of that fear has to do with a lack of information, and short inviting the whole world to experience it for themselves in the style of Timothy Leary, rigorous scientific study is the next best way to lift that veil.

Thats where the Beckley Foundation of the UK comes in. Their organization, which aims to bring science back into the world of psychedelics, is helping us all gain a better understanding of both the substance and our own consciousness.

When we last spoke with Amanda Feilding, co-director and founder of Beckley, they had been testing the effects of psilocybin on depression with incredible results. Now she says her focus is mainlyon LSD.

Poor LSD is still not acceptable, Feilding says with a sense of despair in her voice that only someone who truly understands the substance could convey, theres still a terrible taboo on those letters.

Having lived in the world of psychedelics since their heyday Amanda has seen the effect in science, medicine and the counterculture of the 60s. She has also seen a decades long misinformation campaign which has stigmatized recreational users and the years of scientific research with them.

In the 1950s and 60s, more than 3000 research papers were published on the effects of LSD. Among these early researchers was Ronnie Sandison, whose work at Powick Hospital for the mentally ill had become recognized around the world as a breakthrough in the treatment of mental illness until LSDs association with recreational users forced the compound into obscurity.

Even the founder of Alcoholics Anonymous, Bill Wilson lauded LSD as an aid in curing alcoholism a possible use which the Beckley foundation is also looking into. Wilson who famously believed that alcoholics required a spiritual awakening in order to overcome their addiction also believed that LSD could hold the key to that awakening.

Since its founding in 1998, the Beckley Foundation has sought to revive this field of study in the name of the public good it could do. With the use of modern scientific methods and brain imaging technologies Amanda and her team can now bring scientific backing to the experiences that underground users have known for years.

In 2016, the Beckley/Imperial Research Programme produced the first images of the brain on LSD. The study was conducted on 20 volunteers, whose brains were scanned using fMRI and magnetoencephalography (MEG) after receiving either 75 micrograms of LSD or placebo.

The images, published in Proceedings of the National Academy of Sciences, displayed a luminous picture of the brain in which the Default Mode Network (DMN) had been dissolved. In other words, the rigid wiring of the brain had been freed up to enable greater connectivity. This explains the increased creativity that users experience, but it also allows for therapy to be more effective.

It shakes the rigidity of the setting, Amada explains, Mental and psychological disorder like depression, addiction, PTSD are set on hyperactivity in parts of the Default Mode Network, which is like the ego, its set into a rigid and negative setting.

For recreational users, the images provided an visual representation of the illusive ego death. Its something of a mythologized holy grail of psychedelics or a state of nirvana that is now better understood by looking at the way in which LSD affects the brain.

Ego death or ego disintegration is really the same as the flip side of the expression of the mystical experience. Amada says, The ego is basically the control mechanism to keep the status quo as it is, when that diminishes in its activity there is a flood of other activity which is rather like when the cat is away the mice will play.

That level of free-form thought can be quite overwhelming, especially when the average trip could take up to8-10 hours. This is why Amanda emphasizes that the proper setting and in the case of Beckleys studies a therapeutic guide is important to ensure a positive experience. She also believes that maintaining a regular blood glucose level is an effective way to maintain clarity and stave off a bad trip. Its one theory she aims to test in upcoming studies.

Among itss newest ventures, the Beckley/Imperial Research Programme will undergo the worlds first microdosing study to investigate reports that minor doses of around 15 micrograms increase productivity while still allowing the user to function normally. The study will have volunteers playthe ancient Chinese strategy game of Go, with one player having taken a microdose and the other a placebo, to investigate whether small doses of LSD can enhance intuitive pattern recognition and creativity. All of which is to increase our understanding of LSD, rather than base our knowledge on years of misinformation.

As a once recreational user Amanda is aware of the stigma that can affect its widespread acceptance, but also believes that there are immense benefits in bringing it out of the dark.

I think LSD has gone through a great black tunnel of publicity. Shesays, In many ways I think one can say that its the most adaptable and positive of all the drugs because what it does is expand the inner person.

For her, Beckleys work is about a much more than having a way to legally access a drug again. Its a social duty if you like, its much easier to just take LSD when youre not having to change the world.

In fact, LSD is quite available already and even relatively inexpensive on the black market, but the point of psychedelic science is education rather than access. Understanding these feared substances and the way they affect the body can ultimately help us to provide the safest possible methods of using them. Whether it be recreational of medicinal, more information is always better than propaganda, but wherever the future of psychedelics leads, its sure to be a more enlightened place.

To support the research of MAPS and the Beckley Foundation visit the links below:

MAPS

Beckley

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Modern psychedelic science is reviving lost research and finding new cures - The Plaid Zebra (blog)

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Expanding consciousness – 48 Hills

Posted: at 6:26 pm

At some point, humankind will look back and figure out what to make of our heavy usage of psychedelics at music festivals. Despite the fact that mega-events provide probably the worst atmosphere for astral introspection, many peoples first mushroom or acid trips still happen at mobbed festivals or maybe the hardest trip theyll ever trip will take place at one. Hello, 21-year-old me at Reggae on the River. (I am not ashamed.)

The ritual of ingestion is often articulated in traditional cultures by a shaman or a guide well-read in the ways of certain substances. But in contrast with ayahuasca ceremonies, at Coachella or Burning Man psychedelic use is presided over by musicians on a stage set thousands of people away or by a friend who is just as dehydrated and medicated as you are or no one, when a overpowering wave of crowd splinters a crew.

Lacking a safe container to trip in, psychedelic complications are bound to happen in the haphazard setting of festival madness. Psychedelic users who become violent or otherwise unresponsive to official suggestion via a difficult trip can wind up at the hospital or worse, jail. Neither place is likely to alleviate the paranoia or fear theyre experiencing.

Drug research and education organization MAPS (Multidisciplinary Association For Psychedelic Studies) stepped into this disconnect when it raised the first incarnation of its Zendo Project at Burning Man in 2012. The on-site counseling program complimented MAPS larger mission to advocate for the therapeutic uses of psychedelics. The groups work often focuses on the way that drugs can be used to open up healing emotional pathways, such as a 2016 study that looked at the effects of MDMA on people suffering from PTSD.

The term psychedelic means mind manifesting, which means that our conscious mind becomes aware of subconscious things, says Sara Gael, MAPS director of harm reduction and Zendo Project organizer who has been involved since the year the program came to life and is a firm believer in the benefits associated with responsible usage of the drugs. Thats what therapy is about, exploring the subconscious and the aspects of self that society has taught us to repress.

In the uncertainty of festival chaos, worries about personal sanity or safety can complicate a psychedelic trip, rendering it all but impossible to stay open to the painful realizations that psychedelics can trigger. The Zendos infrastructure responds to this construct; volunteers erect a tent where triggered festival attendees can rehydrate, lie down, and/or snack, in addition to connecting with trained souls ready to sit with them through any threatening visions or panic-inducing paranoias.

Some of the more challenging cases we experience are people who are really frightened, who might then become aggressive, or try to run away, or feel really lost or paranoid, says Gael. Those are some of the more difficult situations to work with because were trying to keep that person physically safe. Thats why we work in collaboration with medical and security.

Today, the Zendo Project has helped 2,900 people at large events, teaming up with security and medical festival staff so that attendees receive the best treatment for their particular situation. Given the projects success, it is pleasant to imagine a larger diversity of gatherings in which Zendo-like harm reduction efforts were present. Currently, the program is limited to Burning Man and its regional events from South Africa to San Diego, in addition to the other transformational endeavors (Lightning in a Bottle, Costa Rican yoga and spirituality fest Envision.)

The Zendo Project is looking to expand, and is currently in the middle of a fundraising drive. And MAPS just publishedThe Manual of Psychedelic Support, a thick tome available for free download.

The manual outlines the logistics behind setting up a Zendo Project-like space, not to mention the inclusion of a fascinating history of harm reduction in modern Western festival culture (the original Woodstock festivals Hog Farmers, founded by Wavy Gravy, are considered pioneers in the area) and the Zendo Projects guiding principles for interactions with those on tough trips: creating a safe space, sitting not guiding, talking through and not down, and difficult is not the same as bad, in Gaels summarization.

Gael is quick to note that the core principles can even be self-applied, if you can remember them should you enter into a difficult trip yourself. When asked for a couple quick pointers for those finding themselves on shaky psychedelic ground, she ventured: What is coming up, try to turn into it rather than away from it, because what we resist, persists. Try to find a safe space away from noise with people that you trust. Find someone who is able to sit with you even if theyre not formally trained, who is not freaking out. Trying to connect with your breath and body, connecting with nature can be really helpful, finding a tree.

She adds that if youre still feeling shaken up even after youve become sober, MAPS has published a list of therapists who are educated in psychedelic integration, or the practice of connecting the dots between psychedelias half-processed self realizations.

It is clear that modern day Western society takes psychedelics under much different circumstances than the cultures that previously utilized the substances. The ritual of loading ones car up with friends and alcohol en route to Electric Daisy Carnival has little in common with the temazcals and sacrament of a Navajo peyote ceremony.

MAPS makes it clear that as part of a harm reduction strategy, the Zendo Project simply responds to the reality that this is the current situation, says Gael. And that despite policy, [psychedelic usage] is going to continue. After nearly 50 years of practice, however, new forms of psychedelic guidance in certain modern day sites of cultural ritual are being developed a nascent safety net for the psychedelic voyagers of today.

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Expanding consciousness - 48 Hills

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Is Qualia Revolutionary or Just Another Nootropic? – HuffPost

Posted: at 6:26 pm

Within the nootropics world there are at least 2 - 3 new unique smart drugs released every month. Some are run of the mill and others are more sophisticated. Qualia was launched by the Neurohacker Collective in April 2016 and has grown rapidly since then. This Qualia supplement review provides a solid non-biased overview, but today were focusing more on the long-term nature of this brand and product.

Qualia and the Neurohacker Collective are positioning themselves to be revolutionary within the space, but is this simply good marketing or a sign of something more.

Qualia Supplement vs Unique Nootropic Blends

The Qualia nootropic supplement consists of 42 separate ingredients split into two stacks. A user of Qualia might balk at consuming 9 pills per day, but it seems the brand is more focused on comprehensive cognitive enhancement as opposed to just another product.

Compared to some of the other nootropic brands in the marketplace, this is quite a different approach. Alpha Brain, one of the most well-respected and popular nootropic stacks, is the product of Onnit, LLC. This product includes only 12 ingredients and many (like oat straw) are of dubious quality (or simply fillers).

Even though Alpha Brain is well-respected because of their placebo-controlled study at the Boston Center for Memory, the bacopa monnieri alone could have caused this result. Finally, Onnit has decided to hide the ingredients and their doses for Alpha Brain behind proprietary blends. This lack of transparency is a major weak point.

In comparison, the Neurohacker Collective has provided clear doses of all their ingredients in addition to utilizing mostly solid doses and ingredients.

Comparing Qualia with OptiMind shows similar disparities. Their product includes only 14 ingredients and some of which arent effective (GABA for example). Again, they too have created a nootropic stack that has grown in popularity, but with non transparent tactics. Their exact doses are hidden behind a proprietary focus blend.

From looking at these two most popular nootropic stacks, it is clear that the Neurohacker Collective is producing something to revolutionize the nootropic industry. Not only are they transparent and using quality ingredients, but they are also using ingredients of questionable status (such as noopept and centrophenoxine).

By pushing the envelope with their product, they are assuredly revolutionizing the nootropics industry.

Yet, they are doing far more than that...

Its hard for a supplement to be revolutionary unless the team behind the product is worthwhile. The management team at the Neurohacker Collective far exceeds that of most other nootropic blends.

Their team is both highly effective in different domains and forward thinking. Between the leadership and scientific expertise, this team is grounded in revolutionary ideas and their methods of operating the business reflect as much.

Jordan Greenhall - The CEO of the Neurohacker Collective has developed many disruptive technologies including DivX and many others. His interests in complex systems and artificial intelligence have led him to investments and projects that transcend mere brain supplements.

James Schmachtenberger - Another founder of the team, James has helped bring medical marijuana into California and has fought organizations that limited the spread of this useful plant.

Daniel Schmachtenberger - As the member of major think-tanks, Daniel has spent ample time disrupting industries and paving the way for radical change.

All three of these leaders, combined with scientists and doctors from Stanford University and others, are highly effective but forward thinking. Their interests with Neurohacker Collective transcend basic cognitive enhancement and hope to radically alter humankind.

This is clearly evidenced in their method o funding.

Most companies, especially in the supplement space, are not transparent at all let alone with their finances. The Qualia nootropic is one of the first to be crowdfunded at a later stage. Rather than simply launching a Kickstarter campaign, its possible to own equity in the Neurohacker Collective as a member of the public.

In a recent WeFunder campaign, the Neurohacker Collective opened up their books to provide consumers the opportunity to own the company they support. This is a revolutionary approach to business within the nootropics industry and is assuredly a sign of the team and their forward looking desires.

This is the final component suggesting that the Qualia nootropic, and the Neurohacker Collective, is more than just another nootropic. Only time will tell whether they are truly revolutionary, but they seem off to a good start.

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‘I was in a zombified trance’, alleged victim of Keighley church minister’s sexual assaults tells jury – Bradford Telegraph and Argus

Posted: at 6:25 pm

A TEENAGER was in a "zombified" trance when a church minister sexually molested her to drive out demons and lustful spirits, Bradford Crown Court heard.

Now in her 40s, the witness told the jury that Pastor John Wilson abused her over a ten year period when he ran a Pentecostal group in Keighley and Shipley.

The woman said she was suicidal when she was a teenager and Wilson held all day private prayer sessions with her.

She looked on him as a father figure and someone to confide in within the church.

She alleged that Wilson, 70, of Shann Avenue, Keighley, put his hand up her skirt to indecently assault her, and touched her breasts, after putting her in a trance during the prayer sessions.

She told the jury on a video link that she was aged about 15 when the one-to-one prayer sessions with Wilson started.

The woman told the court: "He changed from being nice to being a nasty person; demons, demons, spirits, spirits, all the time, drilling it into you, making you believe he was the only one who could take the pain and suffering away from you."

Wilson denies sexually abusing seven women to rid them of evil spirits. He pleads not guilty to 31 allegations, including two of rape, 24 of indecent assault, four of conspiracy to commit indecent assault and one charge of sexual assault.

He denies 11 charges of indecent assault and one of conspiracy to commit indecent assault against the woman, who was giving evidence yesterday.

Wilson's wife, Mary Wilson, 79, of the same address, pleads not guilty to two charges of indecent assault and a single allegation of conspiracy to commit indecent assault.

Laurence Peterson, 59, of Eric Street, Keighley, denies three charges of indecent assault and four allegations of conspiracy to commit indecent assault.

The woman told the jury that Peterson was present during the prayer sessions but she did not recall him ever touching her.

She said she began attending the Pentecostal church as a young girl. She said she had been abused by a man at a fairground and Wilson offered spiritual comfort.

The woman said Peterson made tea before the prayer sessions and she became "zoned out". She was in a trance and "zombified" when Wilson was abusing her.

"It is so devastating that a person who was in a position of authority would do that," she said.

"He made me an emotional wreck."

She said the abuse continued after she married. She said she woke naked on one occasion with carpet burns on her back.

"It was like I was stuck to the floor in a trance, in a daze. I knew I was naked. I knew he had touched me," she told the jury.

"It just cuts me up inside how he could just do that and get away with it."

The trial continues.

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Is Edap Tms SA Adr (NASDAQ:EDAP)’s Fuel Running Low? Reports Show More Sellers – BZ Weekly

Posted: at 6:24 pm

August 1, 2017 - By Hazel Jackson

The stock of Edap Tms SA Adr (NASDAQ:EDAP) registered an increase of 83.75% in short interest. EDAPs total short interest was 774,700 shares in August as published by FINRA. Its up 83.75% from 421,600 shares, reported previously. With 230,900 shares average volume, it will take short sellers 3 days to cover their EDAPs short positions. The short interest to Edap Tms SA Adrs float is 2.8%.

About 5,840 shares traded. Edap Tms SA (ADR) (NASDAQ:EDAP) has declined 15.92% since August 1, 2016 and is downtrending. It has underperformed by 32.62% the S&P500.

EDAP TMS S.A. is a holding company engaged in developing and marketing the Ablatherm and Focal One devices. The company has market cap of $90.58 million. The Firm operates two divisions: High Intensity Focused Ultrasound (HIFU) and Urology Devices and Services (UDS) (including lithotripsy activities). It has a 19.49 P/E ratio. The Firm is developing HIFU technology for the treatment of certain other types of tumors.

More news for Edap Tms SA (ADR) (NASDAQ:EDAP) were recently published by: Marketwatch.com, which released: Symbol Lookup on June 08, 2009. Quotes.Wsj.coms article titled: EDAP TMS SA ADR and published on February 11, 2011 is yet another important article.

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Cf Industries Holdings, Inc. – CF – Stock Price Today – Zacks

Posted: at 6:23 pm

Zacks Earnings ESP (Expected Surprise Prediction) looks to find earnings surprises by focusing on the most recent analyst revisions. This is done because, generally speaking, if an analyst reevaluates their earnings estimate right before an earnings release, it means that they have fresh information which could potentially be more accurate than what analysts thought about a company two or three months ago.

The crux of this approach is comparing the Most Accurate Estimate to the Zacks Consensus Estimate, although the Zacks Rank is also an important feature of the ESP metric. Combining these two can help investors find stocks that are ready to beat the consensus at their next report, and hopefully surge higher in price too.

In fact, when combining a Zacks Rank #3 or better and a positive Earnings ESP, stocks produced a positive surprise 70% of the time. And best of all, by using these parameters, investors have seen 28.3% annual returns on average, according to our 10 year backtest.

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Zacks Earnings ESP (Expected Surprise Prediction) looks to find companies that have recently seen positive earnings estimate revision activity. The idea is that more recent information is, generally speaking, more accurate and can be a better predictor of the future, which can give investors an advantage in earnings season.

The technique has proven to be very useful for finding positive surprises. In fact, when combining a Zacks Rank #3 or better and a positive Earnings ESP, stocks produced a positive surprise 70% of the time, while they also saw 28.3% annual returns on average, according to our 10 year backtest.

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FDA Approves Kalydeco for 600 CF Patients with Specific Mutations – Cystic Fibrosis News Today

Posted: at 6:23 pm

The U.S. Food and Drug Administration (FDA) has approved Kalydeco (ivacaftor) to treat more than 600 of the estimated 30,000 Americans with cystic fibrosis (CF), Vertex Pharmaceuticals announced.

The oral medicine may now be prescribed to CF patients ages 2 and older who have one of five residual function mutations that result in a splicing defect in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, according to Vertex.

The FDA based its Aug. 1 approval on Phase 3 clinical data for Kalydeco in these mutations. This follows previous FDA approvalsof the drug in May 2017 for 23 other residual function mutations. The agencys first approval of Kalydeco was in January 2012 for 10 mutations in the CFTR gene.

Tuesdays announcement brings the number of CFTR mutations that Kalydeco may treat to 38 out of a possible 2,000 or so known mutations in the gene. Boston-based Vertex said both 2017 FDA approvals are supported by more than five years of real-world clinical experience that demonstrates Kalydecos established safety and effectiveness.

In the five years since Kalydeco became the first approved medicine to treat the underlying cause of cystic fibrosis, we have been relentless in our efforts to bring this important medicine to all who may benefit, Dr. Jeffrey Chodakewitz, executive vice president and chief medical officer at Vertex, said in a press release. We will continue to pursue this goal until all people with CF have a medicine that treats their form of this serious and life-shortening disease.

Kalydeco is the first medicine to treat the underlying cause of CF in people with those specific CFTR mutations. It is designed to keep CFTR proteins at the cell surface open longer to improve the transport of salt and water across the cell membrane, which helps hydrate and clear mucus from the airways.

According to Vertex, the five mutations covered under the FDAs latest approval cause CF and result in a moderate loss of chloride transport. Patients with these mutations generally experience progressive lung function decline and other complications of the disease. All five mutations were evaluated as part of the previously disclosedPhase 3 EXPAND studyin which Kalydeco as a monotherapy met its primary efficacy endpoint and was generally well tolerated.

Following the FDA announcement, Vertex raised projected 2017 sales of Kalydeco to between $770 million and $800 million. It now expects total CF product revenues to reach anywhere from $1.87 billion to $2.1 billion; well over half that total will come from sales of another CF therapy, Orkambi.

Kalydecos discovery stems from a CF research program initiated by Vertex in 2000 as part of a collaboration with Cystic Fibrosis Foundation Therapeutics, an affiliate of the nonprofit Cystic Fibrosis Foundation, based in Bethesda, Maryland.

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FDA Approves Kalydeco for 600 CF Patients with Specific Mutations - Cystic Fibrosis News Today

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