Daily Archives: April 5, 2017

NASCAR drivers don’t know what to expect from TMS’ repave – Fort Worth Star Telegram

Posted: April 5, 2017 at 4:54 pm


Fort Worth Star Telegram
NASCAR drivers don't know what to expect from TMS' repave
Fort Worth Star Telegram
TMS has tried to work as much rubber into the new surface as possible with the Texas Tire Monster, as well as the Tire Dragon sent by sister track Kentucky Speedway. I'm shocked that we didn't get a whole day of testing to try to get the car set up ...
Other Sports: Full schedule of events for O'Reilly Auto Parts 500 at ...Dallas News

all 14 news articles »

Continue reading here:

NASCAR drivers don't know what to expect from TMS' repave - Fort Worth Star Telegram

Posted in Tms | Comments Off on NASCAR drivers don’t know what to expect from TMS’ repave – Fort Worth Star Telegram

Missing CF man found in Brule River – Iron County Reporter

Posted: at 4:53 pm

FLORENCE, Wis.The body of a missing 60-year-old Crystal Falls man was recovered from the Brule River in Florence Township by authorities on March 29, the Florence County Sheriffs Office said in a news release. Jerry Hamilton had been reported missing since March 27 after his vehicle had been found near a boat landing in Florence County. A preliminary autopsy showed that Hamilton died of drowning. Nothing was discovered during the autopsy that would indicate foul play. The investigation is continuing pending the results of toxicology reports. Deputies from the Florence County Sheriffs Office and wardens from the Wisconsin and Michigan Departments of Natural Resources recovered Hamiltons body at 4:43 p.m. The body was located by a remotely operated vehicle that was deployed by wardens from the Wisconsin DNR. Hamiltons body was located in 5 feet of water, approximately 10 feet from where his vehicle was found. Hamilton was pronounced dead at the scene by Florence County Coroner Mary Johnson. The Florence County Sheriffs Office received a call from a citizen March 27 reporting a car on the ice on the Brule River, approximately 400 yards upstream from the boat landing. When deputies arrived on the scene, they discovered the front half of the vehicle was on the ice and the back half was in open water. Authorities said it appeared that Hamilton may have tried to turn his vehicle around when the back tires fell off the ice into open water. Hamilton was last seen by a family member on March 26 at approximately 8 p.m., according to the Florence County Sheriffs Office. The Florence County Sheriffs Office was assisted by the Wisconsin DNR, Michigan DNR and Florence Fire Department. The Michigan DNR also provided a fixed wing plane to fly the Brule River.

Read the rest here:

Missing CF man found in Brule River - Iron County Reporter

Posted in Cf | Comments Off on Missing CF man found in Brule River – Iron County Reporter

Analyst Activity BMO Capital Markets Reiterates Buy on CF Industries Holdings (NYSE:CF) – Market Exclusive

Posted: at 4:53 pm


Free Observer
Analyst Activity BMO Capital Markets Reiterates Buy on CF Industries Holdings (NYSE:CF)
Market Exclusive
Today, BMO Capital Markets reiterated its Buy rating on CF Industries Holdings (NYSE:CF) with a price target of $38.00. There are 2 sell ratings, 8 hold ratings, 4 buy ratings on the stock. The current consensus rating on CF Industries Holdings (NYSE ...
Highly Traded Stock: CF Industries Holdings, Inc. (CF)HugoPress
CF Industries Holdings, Inc. (CF): From Top to BottomStockNewsJournal
CF Industries Holdings, Inc. surged in the Previous Trading Session with the Change of 2.85%Free Observer
Equities.com -Herald KS -The USA Commerce
all 24 news articles »

View post:

Analyst Activity BMO Capital Markets Reiterates Buy on CF Industries Holdings (NYSE:CF) - Market Exclusive

Posted in Cf | Comments Off on Analyst Activity BMO Capital Markets Reiterates Buy on CF Industries Holdings (NYSE:CF) – Market Exclusive

CF Ireland call for decision on life-saving drug – Galway Independent

Posted: at 4:53 pm

Cystic Fibrosis Ireland is again appealing to the government to approve ground-breaking therapies for people with the disease.

The plea comes ahead of Cystic Fibrosis National Awareness Week, which runs from 10-16 April.

The HSE has yet to confirm whether it will make Orkambi available - a life-changing drug that could significantly improve CF patients quality of life.

Chairperson of CF Galway, Mary Lane Heneghan is calling on the government to conclude its discussions with the drug manufacturer, Vertex Pharmaceuticals, and to give swift approval for the Orkambi therapy.

The drug is estimated to cost 159,000 per patient.

She said it is hard for CF patients and their families to listen to the issue being played out in the public eye.

Its not fair on the families and the people with CF out there that all of this is played out on the airwaves. I know it has to be, but its just very difficult for the parents and for the adults in particular.

Ms Lane Heneghan is hopeful the HSE will come to a decision by the end of this week.

The latest figures from the Cystic Fibrosis Registry of Ireland show that in 2015 there were 1,219 people registered with CF, with 19 years the median age.

65 Roses Day

65 Roses Day so-named after the way in which young children are first taught to say the words Cystic Fibrosis will see the country awash with purple next Thursday, 13 April as volunteers take to the streets and shopping centres selling purple roses with the aim of raising 100,000. Monies will go to fund the development of dedicated healthcare facilities, research, counselling and much-needed grant supports for people with CF in areas such as transplant assessment, fertility and bereavement.

Galway Events

It will be all guns blazing in Galway next week, according to Ms Lane Heneghan, with a number of events scheduled to take place in aid of CF.

TY students at St Brigids Vocational College Loughrea along with their TY Co-ordinator Ms Flanagan are organising an awareness and fundraising event on 13 April. There will also be a poker game in St Michael's Community Hall Craughwell on Friday 14, as well as a quiz in Dan's Bar Athenry organised by Ronan Cahill who is cycling Malin2Mizen for CF in May and an event in Mayfly Inn Oughterard plus a memorial walk to Mameam.

Eyre Square Shopping Centre, Bank of Ireland Oranmore and Londis Kilcolgan will also be selling 65 Roses.

Ms Lane Heneghan said they are totally dependent on the generosity of local people and she thanked those for continuing to support the organisation.

You can lend your support by buying a purple rose for 2, making a 2 text donation by texting 65ROSES to 50300 or donating online atwww.65rosesday.ie

Read more from the original source:

CF Ireland call for decision on life-saving drug - Galway Independent

Posted in Cf | Comments Off on CF Ireland call for decision on life-saving drug – Galway Independent

Subcloning – Wikipedia

Posted: at 4:51 pm

In molecular biology, subcloning is a technique used to move a particular DNA sequence from a parent vector to a destination vector.

Subcloning is not to be confused with molecular cloning, a related technique.

Restriction enzymes are used to excise the gene of interest (the insert) from the parent. The insert is purified in order to isolate it from other DNA molecules. A common purification method is gel isolation. The number of copies of the gene is then amplified using polymerase chain reaction (PCR).

Simultaneously, the same restriction enzymes are used to digest (cut) the destination. The idea behind using the same restriction enzymes is to create complementary sticky ends, which will facilitate ligation later on. A phosphatase, commonly calf-intestinal alkaline phosphatase (CAIP), is also added to prevent self-ligation of the destination vector. The digested destination vector is isolated/purified.

The insert and the destination vector are then mixed together with DNA ligase. A typical molar ratio of insert genes to destination vectors is 3:1;[1] by increasing the insert concentration, self-ligation is further decreased. After letting the reaction mixture sit for a set amount of time at a specific temperature (dependent upon the size of the strands being ligated; for more information see DNA ligase), the insert should become successfully incorporated into the destination plasmid.

The plasmid is often transformed into a bacterium like E. coli. Ideally when the bacterium divides the plasmid should also be replicated. In the best case scenario, each bacterial cell should have several copies of the plasmid. After a good number of bacterial colonies have grown, they can be miniprepped to harvest the plasmid DNA.

In order to ensure growth of only transformed bacteria (which carry the desired plasmids to be harvested), a marker gene is used in the destination vector for selection. Typical marker genes are for antibiotic resistance or nutrient biosynthesis. So, for example, the "marker gene" could be for resistance to the antibiotic ampicillin. If the bacteria that were supposed to pick up the desired plasmid had picked up the desired gene then they would also contain the "marker gene". Now the bacteria that picked up the plasmid would be able to grow in ampicillin whereas the bacteria that did not pick up the desired plasmid would still be vulnerable to destruction by the ampicillin. Therefore, successfully transformed bacteria would be "selected."

In this example, a gene from mammalian gene library will be subcloned into a bacterial plasmid (destination platform). The bacterial plasmid is a piece of circular DNA which contains regulatory elements allowing for the bacteria to produce a gene product (gene expression) if it is placed in the correct place in the plasmid. The production site is flanked by two restriction enzyme cutting sites "A" and "B" with incompatible sticky ends.

The mammalian DNA does not come with these restriction sites, so they are built in by overlap extension PCR. The primers are designed to put the restriction sites carefully, so that the coding of the protein is in-frame, and a minimum of extra amino acids is implanted on either side of the protein.

Both the PCR product containing the mammalian gene with the new restriction sites and the destination plasmid are subjected to restriction digestion, and the digest products are purified by gel electrophoresis.

The digest products, now containing compatible sticky ends with each other (but incompatible sticky ends with themselves) are subjected to ligation, creating a new plasmid which contains the background elements of the original plasmid with a different insert.

The plasmid is transformed into bacteria and the identity of the insert is confirmed by DNA sequencing.

Continue reading here:

Subcloning - Wikipedia

Posted in Cloning | Comments Off on Subcloning – Wikipedia

Most victims of card cloning govt employees – Times of India

Posted: at 4:51 pm

Lucknow: Analysing profiles of those duped by a Gujarat-based gang involved in cloning of debit and credit cards, police found majority of them were government employees. 12 FIRs have been lodged since April 1 and over 50 complaints have been received. In what seems to be the job of an organised gang of cyber criminals with countrywide reach, debit cards of Lucknow residents were cloned and money withdrawn in Vadodara on April 1, 2 and 3 though the cards remained in possession of their original owners throughout. Policemen at Hazratganj-based cyber cell found out that on April 1, bank accounts of 11 government employees were hacked to bungle close to Rs 3 lakh on a single day. Eight of these are working at government offices located in Indira Bhawan or Jawahar Bhawan in Hazratganj while remaining three worked at other government offices in Hazratganj. "Their complaints have been clubbed and FIR had been lodged at Hazratganj police station as that will make it easier to claim money for these victims. Others have also been directed to register FIRs at the nearest police stations," said VVS Sirohi, in-charge of cyber cell.

See more here:

Most victims of card cloning govt employees - Times of India

Posted in Cloning | Comments Off on Most victims of card cloning govt employees – Times of India

Series of cloning cases reported in city | Lucknow News – Times of … – Times of India

Posted: at 4:51 pm

LUCKNOW: In an unusual development, March 31, the closing of banking operations, coincided with large scale cyber frauds in the city. More than 50 cases of cloning have been reported with 36 complaints being brought to the notice of Hazratganj-based cyber cell on April 1, 2 and 3. In what seems to be the work of an organised cyber gang with countrywide reach, a common plot has been detected in such frauds. Cyber cell incharge VVS Sirohi said at least Rs 10 lakh has been swindled from bank accounts in three days. "We feel that some hackers managed to get their hands on confidential customer information of a particular bank branch in Hazratganj. A report will be forwarded to the data center of the bank in Mumbai for further clarity," said Sirohi. While debit cards of the customers remained in their possession, they got text messages about withdrawals. Miscreants used the card twice to take out Rs 40,000, in most of the cases. Sub-inspector Sudheer Kumar Gautam was also targeted by the gang on April 1. "I started following up on the case and found that many more people have been duped. Two other constables had Rs 40,000 withdrawn from their accounts," said Gautam. On Tuesday, a police team inspected the ATM booth outside the Ashok Marg branch of the bank, the place where 60% of the victims hold savings account. Fraudulent transactions have been undertaken in Vadodara in all the cases. Sirohi said earlier too a gang which skimmed debit card data had been busted in city. "We are finding out if the same miscreants have come out on bail," said Sirohi.

Read the rest here:

Series of cloning cases reported in city | Lucknow News - Times of ... - Times of India

Posted in Cloning | Comments Off on Series of cloning cases reported in city | Lucknow News – Times of … – Times of India

3700-Year-Old Pyramid May Yield Clues to Tomb Evolution – History

Posted: at 4:51 pm

South of Cairo, at the Dahshur royal necropolis, the remains of a pyramid that may date back some 3,700 years ago have been discovered.

The pyramid was discovered by an Egyptian archaeological mission working approximately 25 miles south of Cairo, near the location of King Sneferus Bent Pyramid. Adel Okasha, the head of the Dahshur necropolis site, confirmed that the team uncovered an interior corridor leading to the inside of the pyramid, a hall leading to a southern ramp and a room at the western end. Inside the corridor, they also discovered an alabaster block measuring 15-by-17 centimeters (roughly 6-by-6 inches), engraved with 10 vertical hieroglyphic lines.

The head of the Ancient Egyptian Antiquities Sector, Mahmoud Afifi, confirmed in a statement that a granite lintel (likely used to support a door or entrance) and a collection of stone blocks showing the interior design of the pyramid were also found. Luckily, the pyramid remains are reported to be in good condition.

This forgotten pyramid at Dahshur is already unique. While the vast majority of Egypts pyramids were constructed during the Old and Middle Kingdoms (from the 3rd to the 12th dynasties). This newly found pyramid is believed to date to the 13th dynasty, when only a few pyramids were constructed. The last structure built during this dynasty was the pyramid of Ahmose, an 18th dynasty king, but historians believe it was used as a cenotaph (or monument) rather than a tomb.

Dahshur is a royal necropolis on the west bank of the Nile. Its home to numerous pyramids, including two of the oldest, largest and best preserved examples, both built by King Senferu during Egypts 4th Dynasty, a golden age that lasted from 2613 to 2494 B.C. The first, known as the Bent Pyramid, was constructed with slopes that change angles from 54 degrees to 43 degrees about halfway up. The second, known as the Red Pyramid for its limestone hue, is the third-largest pyramid ever constructed, and has been seen by many (at least until now) as Egypts first success at constructing a true smooth-sided pyramid.

While King Sneferus Bent Pyramid is seen by some as the first attempt to build a smooth-sided pyramid, other researchers have argued that it was the transitional form between step-sided and smooth-sided pyramids. The bent slope sides of this newly discovered pyramid begs the question, could this forgotten pyramid actually be ancient Egypts first successful smooth-sided pyramid?

The Dashur necropolis was used as a burial site for courtiers and high-ranking officials, as well as royals, and authorities have not yet confirmed the identity of who was buried there. Further excavations are planned to continue to unearth more of the pyramid and identify who may have been buried within.

Follow this link:

3700-Year-Old Pyramid May Yield Clues to Tomb Evolution - History

Posted in Evolution | Comments Off on 3700-Year-Old Pyramid May Yield Clues to Tomb Evolution – History

New approach developed by humanists and scientists maps evolution of literature – Phys.Org

Posted: at 4:51 pm

April 5, 2017 Credit: Elena Poiata

A classicist, biologist and computer scientist all walk into a roomwhat comes next isn't the punchline but a new method to analyze relationships among ancient Latin and Greek texts, developed in part by researchers from The University of Texas at Austin.

Their work, referred to as quantitative criticism, is highlighted in a study published in the Proceedings of the National Academy of Sciences. The paper identifies subtle literary patterns in order to map relationships between texts and more broadly to trace the cultural evolution of literature.

"As scholars of the humanities well know, literature is a system within which texts bear a multitude of relationships to one another. Understanding what is distinctive about one text entails knowing how it fits within that system," said Pramit Chaudhuri, associate professor in the Department of Classics at UT Austin. "Our work seeks to harness the power of quantification and computation to describe those relationships at macro and micro levels not easily achieved by conventional reading alone."

In the study, the researchers create literary profiles based on stylometric features, such as word usage, punctuation and sentence structure, and use techniques from machine learning to understand these complex datasets. Taking a computational approach enables the discovery of small but important characteristics that distinguish one work from anothera process that could require years using manual counting methods.

"One aspect of the technical novelty of our work lies in the unusual types of literary features studied," Chaudhuri said. "Much computational text analysis focuses on words, but there are many other important hallmarks of style, such as sound, rhythm and syntax."

Another component of their work builds on Matthew Jockers' literary "macroanalysis," which uses machine learning to identify stylistic signatures of particular genres within a large body of English literature. Implementing related approaches, Chaudhuri and his colleagues have begun to trace the evolution of Latin prose style, providing new, quantitative evidence for the sweeping impact of writers such as Caesar and Livy on the subsequent development of Roman prose literature.

"There is a growing appreciation that culture evolves and that language can be studied as a cultural artifact, but there has been less research focused specifically on the cultural evolution of literature," said the study's lead author Joseph Dexter, a Ph.D. candidate in systems biology at Harvard University. "Working in the area of classics offers two advantages: the literary tradition is a long and influential one well served by digital resources, and classical scholarship maintains a strong interest in close linguistic study of literature."

Unusually for a publication in a science journal, the paper contains several examples of the types of more speculative literary reading enabled by the quantitative methods introduced. The authors discuss the poetic use of rhyming sounds for emphasis and of particular vocabulary to evoke mood, among other literary features.

"Computation has long been employed for attribution and dating of literary works, problems that are unambiguous in scope and invite binary or numerical answers," Dexter said. "The recent explosion of interest in the digital humanities, however, has led to the key insight that similar computational methods can be repurposed to address questions of literary significance and style, which are often more ambiguous and open ended. For our group, this humanist work of criticism is just as important as quantitative methods and data."

Explore further: The 'close reading' of multicultural literature expands racial literacy, scholar says

More information: Joseph P. Dexter et al, Quantitative criticism of literary relationships, Proceedings of the National Academy of Sciences (2017). DOI: 10.1073/pnas.1611910114

While the phrase "close reading" may not resonate for someone outside of an English department, Stanford literary scholar Paula Moya wants to reclaim the useful literary tool, especially when it comes to multicultural writers.

Heated debates about the quantifiable value of arts and literature are a common feature of American social discourse. Now, two researchers from The New School for Social Research have published a paper in Science demonstrating ...

Maps help us locate landmarks and can even trace historical change.

The social networks behind one of the most famous literary controversies of all time have been uncovered using modern networks science.

When a 2013 study published in Science concluded that reading literary fiction for as few as 20 minutes could improve someone's social abilities, it made quite the splash. However, when researchers from the University of ...

University of Illinois English professor Ted Underwood recently wrapped up a research project involving more than 4,200 books. Since that work revealed dramatic shifts in the English language between the 18th and 19th centuries, ...

Oxford University researchers have tracked how recent aircraft incidents or accidents trigger past events and how some are consistently more memorable than others. Using the English version of Wikipedia, they analysed articles ...

A classicist, biologist and computer scientist all walk into a roomwhat comes next isn't the punchline but a new method to analyze relationships among ancient Latin and Greek texts, developed in part by researchers from ...

Approximately 13,500 years after nomadic Clovis hunters crossed the frozen land bridge from Asia to North America, researchers are still asking questions and putting together clues as to how they not only survived in a new ...

A study of the DNA in ancient skeletal remains adds to the evidence that indigenous groups living today in southern Alaska and the western coast of British Columbia are descendants of the first humans to make their home in ...

A cave in southern Oregon that is the site of some the oldest preserved evidence of human activity in North America was also once home to not-too-distant cousins of the common bed bug.

Reader preferences for liberal or conservative political books also attract them to different types of science books, according to a new study from researchers at the University of Chicago and Yale and Cornell universities. ...

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

More:

New approach developed by humanists and scientists maps evolution of literature - Phys.Org

Posted in Evolution | Comments Off on New approach developed by humanists and scientists maps evolution of literature – Phys.Org

Rankefod takes human evolution on a poetic journey: review – Toronto Star

Posted: at 4:51 pm

Kitt Johnson in Rankefod, part of World Stage at Harbourfront. ( WORLD STAGE )

Kitt Johnson X-act: Rankefod

Choreography by Kitt Johnson

Until Apr. 8, at Harbourfront Centre Theatre, 235 Queens Quay W., or 416-973-4000.

Danish dance artist Kitt Johnson is not the first to attempt to evoke our primordial past through movement. Such efforts can too easily appear corny or, worse still, cute. Instead Johnsons Rankefod is epic and awe-inspiring.

In her 50-minute solo that opened at Harbourfront Centre on Tuesday Johnson takes us on a journey at once strange and haunting, from the infinite vastness of a universe devoid of life to an evolutionary moment when our primitive ancestors took to dry land and hind legs.

An improvised electronic soundscape by Johnsons longtime artistic collaborator Sture Ericson roars deafeningly in the darkness; the birth of the universe perhaps. It then diminishes to a whispering, unworldly ambience.

A dim circle of light gradually intensifies to reveal an unidentifiable creature, a mound of animal matter with a prominent spine suggestive of an exoskeleton. It begins to breathe and pulsate, shooting out stunted bodily appendages in staccato bursts of movement. The creature unfurls, becomes increasingly mobile and scampers about as if exploring unknown terrain.

By now, of course, we know its Johnsons human form generating these images of primitive existence yet, naked except for a rough-textured loincloth and with a blank, glassy-eyed expression on her pale-painted face, we never for a moment see her as anything but pre-human. Now in her late fifties, Johnson remains a formidable presence and performer, her body lithe and expressive.

The solos title is the Danish word for a subclass of crustacea known as cirripedia. Barnacles qualify as such along with various other arthropoda. Its not necessary to know this to appreciate Rankefod although it does help explain some of Johnsons oddly contorted modes of locomotion, redolent of leggy insects or sideways-moving crabs.

Rankefods overall poetic resonance is enigmatic, more easily felt than explained. The image conveyed by designer Charlotte Ostergaards deeply textured backdrop varies according to how it is lit by Mogens Kjempff. It can be a rocky cliff or transform into a barren, gullied landscape. It is towards this that Johnson turns her glance before finally staring out beyond us towards an unseen and, we ponder, threatening future.

This is a return visit to Toronto for Rankefod. Johnson first performed it here nine years ago as part of Harbourfront Centres World Stage, a series presenting both international and Canadian artists from a range of contemporary performance disciplines and their evolving hybrid forms. Now Johnson is the opening event of World Stage Redux, a compact 18-day festival comprising eight programs, three of them featuring Canadian artists.

Launched in 1986, World Stage was once a high-profile festival that introduced Toronto to a host of major international theatre artists but when munificent corporate sponsorships began to dry up World Stage became a more modest although still artistically adventurous series of performances.

This year, as Harbourfront Centre re-evaluates its place in the local cultural landscape, it has opted for an interim to dip into its past with a festival of encore appearances. A combination of timing, logistics and available funding doubtless determined the choices. Five of the eight shows feature solo performers, which of course makes them no less interesting.

This week World Stage Redux also features a fresh iteration of actor Clare Coulter and director Philip McKees exploration of Shakespeares Lear as well as dancer/choreographer William Yongs Steer, an unnerving portrayal of how technology may denude us of our humanity; as if it hasnt already. Among next weeks highlights, if that can properly describe a theatrical memorial to the Holocaust, is Rotterdam-based Hotel Moderns chilling Kamp in which three performers animate the occupants of a roughly 1:20 scale model of Auschwitz. World Stage Redux will end with Mies Julie, South African Yael Frabers contemporary re-imagining of August Strindbergs torrid drama.

The Toronto Star and thestar.com, each property of Toronto Star Newspapers Limited, One Yonge Street, 4th Floor, Toronto, ON, M5E1E6. You can unsubscribe at any time. Please contact us or see our privacy policy for more information.

Go here to see the original:

Rankefod takes human evolution on a poetic journey: review - Toronto Star

Posted in Evolution | Comments Off on Rankefod takes human evolution on a poetic journey: review – Toronto Star