Daily Archives: February 28, 2017

Should artificial intelligence be used in science publishing? – PRI

Posted: February 28, 2017 at 8:08 pm

Advances in automation technology mean that robots and artificial intelligence programs are capable of performing an ever-greater share of our work, including collecting and analyzing data. For many people, automated colleagues are still just office chatter, not reality, but the technology is already disrupting industries once thought to be just for humans. Case in point: science publishing.

Increasingly, publishers are experimenting with using artificial intelligence in the peer review process for scientific papers. In a recent op-ed for Wired, one editor described how computer programs can handle tasks like suggesting reviewers for a paper, checking an authors conflicts of interestand sending decision letters.

In 2014 alone, an estimated 2.5 million scientific articles were published in about 28,000 journals (and thats just in English). Given the glut in the industry, artificial intelligence could be a valuable asset to publishers: The burgeoning technology can already provide tough checks for plagiarism and fraudulent dataand address the problem of reviewer bias. But ultimately, do we want artificial intelligence evaluating what new research does and doesnt make the cut for publication?

The stakes are high: Adam Marcus, co-founder of the blog Retraction Watch, has two words for why peer review is so important to science: Fake news.

Peer review is science's version of a filter for fake news, he says. It's the way that journals try to weed out studies that might not be methodologically sound, or they might have results that could be explained by hypotheses other than what the researchers advanced.

The way Marcus sees it, artificial intelligence cant necessarily do anything better than humans can they can just do it faster and in greater volumes. He cites one system, called statcheck, which was developed by researchers to quickly detect errors in statistical values.

They can do, according to the researchers, in a nanosecond what a person might take 10 minutes to do, he says. So obviously, that could be very important for analyzing vast numbers of papers. But as it trawls through statistics, the statcheck system can also turn up a lot of noise, or false positives, Marcus adds.

Another area where artificial intelligence could do a lot of good, Marcus says, is in combating plagiarism. Many publishers, in fact every reputable publisher, should be using right now plagiarism detection software to analyze manuscripts that get submitted. At their most effective, these identify passages in papers that have similarity with previously published passages.

But in the case of systems like statcheck and anti-plagiarism software, Marcus says its crucial that theres still human oversight, to make sure the program is turning up legitimate red flags. In other words, we need humans to ensure that algorithms arent mistakenly keeping accurate science from being published.

Despite his caution, Marcus thinks programs can and should be deployed to keep sloppy or fraudulent science out of print. Researchers recently pored over images published in over 20,000 biomedical research papers, and found that about one in 25 of them contained inappropriately duplicated images.

I'd like to see that every manuscript that gets submitted be run through a plagiarism detection software system, [and] a robust image detection software system, Marcus says. In other words, something that looks for duplicated images or fabricated images.

Such technology, he says, is already in the works. And then [wed] have some sort of statcheck-like programthat looks for squishy data.

This article is based on aninterviewthat aired on PRI'sScience Friday.

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Britain banks on robots, artificial intelligence to boost growth – Information Management

Posted: at 8:08 pm

(Bloomberg) -- Britain is betting that the rise of the machines will boost the economy as the country exits the European Union.

As part of its strategy to champion specific industries, the U.K. government said in a statement on Sunday that it would invest 17.3 million pounds ($21.6 million) in university research on robotics and artificial intelligence. The government cited an estimate from consultancy Accenture that AI could add 654 billion pounds to the U.K. economy by 2035.

We are already pioneers in todays artificial intelligence revolution and the digital strategy will build on our strengths to make sure U.K.-based scientists, researchers and entrepreneurs continue to be at the forefront, Culture Secretary Karen Bradley said in the statement, which referenced AIs contribution to smartphone voice and touch recognition technologies.

The announcement is part of U.K. Prime Minister Theresa Mays plan to identify industries worth supporting to help transform the economy and boost productivity. The government has said it intends to target areas where it thinks the U.K. could excel in the future, including biotechnology and mobile networking.

The U.K.s digital strategy proposal, set to be unveiled on Wednesday, also includes a review of AI to determine how the government and industry can provide further support.

Investment in robotics and artificial intelligence will help make our economy more competitive, build on our world-leading reputation in these cutting-edge sectors and help us create new products, develop more innovative services and establish better ways of doing business, Business Secretary Greg Clark said in the statement.

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How Are Retailers Using Artificial Intelligence? – eMarketer

Posted: at 8:08 pm

Artificial intelligence (AI) adoption is still limited, but among retail marketers who do employ the technology, many use it in their search or recommendation engines.

A January 2017 survey from Sailthru, which aggregates and analyzes user data sets for companies to create personalized customer experiences, polled retail marketers in Canada, the UK and the US about how they use AI to accomplish their goals. Respondents were primarily from ecommerce retailers, but included retailers with ecommerce and physical retail locations.

The largest share of retail marketers using AIover a thirdsaid they use it in search efforts. Nearly as many said they do so in recommendation engines for their products or content.

Meanwhile, more than a quarter reported using AI in their programmatic advertising efforts, and another 13% in chatbot efforts.

Overall, marketersnot just retail marketersuse different forms of AI.

A separate survey from Narrative Science found that among the 58% of US business executives who already had AI-powered solutions deployed at their company, nearly a third cited voice recognition and voice response solutions as the AI technology they use most.

Just under a quarter (24%) of respondents used AI primarily for machine learning, and 15% used it for virtual personal assistants.

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The mortal side of biological immortality – Kennebec Journal & Morning Sentinel

Posted: at 8:07 pm

As a biological researcher studying aging, some of the most common questions I get asked by people are: How can I live forever? or Have you discovered the fountain of youth yet?

I usually reply with some quirky comment about being close to a Nobel Prize-worthy breakthrough in the lab that is going to be huge. But all kidding aside, there are some organisms that are considered biologically immortal, such as bristlecone pines and marine life we can find along Maines coastline (ex: American lobster, and hydras).

Biological immortality is a bit different than true immortality, in which you live forever and never die. A 100-year-old lobster would be massive, most likely weighing 20-plus pounds and be about the size of a toddler. On a side note, there have been several of these large lobsters documented, one in New Brunswick as recent as last November.

Unlike most animals who stop growing upon reaching adulthood, lobster can continue to expand, molt, and even regrow lost appendages regardless of adult age. Their cells possess the ability to regenerate and dont show signs of deterioration with each consecutive cell division. This provides the lobster a youthful internal system, while appearing mature and hardy on the outside. The larger the body, the less likely the lobster will fall prey to predators such as cod, flounder, and dogfish.

Ultimately, the main predator for adult lobster would be humans. This means that even though biologically the lobster has cells that are immortal they can still become our dinner, and thus succumb to their mortality.

But now the wheels are turning, how can humans reach biological immortality?

Research with model organisms from microscopic yeast to large primates indicates that aging can be slowed down, and perhaps one day reach biological immortality. Science is finding that aging really boils down to a few general factors: 1) genetics, 2) environment, and 3) life choices.

Although we have little control over the genes we are given from our parents, we can control some aspects of gene expression. Certain genes are activated upon eating, others while sleeping, and some while exercising, smoking, imbibing, are drug activated or repressed (and the list can go on). What this means is that we might not be able to control what genes we are given at birth but to some extent we can alter the way genes are expressed.

This is where environment and life choices can really impact the rate in which we age. We heed warnings to stay away from environments containing radioactivity as it can cause death with exposure, but the simple act of reducing the amount of calories ingested daily without reducing nutrition has been shown time and time again to slow down aging (at least in model organisms).

Notice I said this was a simple lifestyle change? Which in reality, is not simple at all. I enjoy eating, drinking, and living this mortal life too much to want to restrict my eating so that I can delay aging. Instead, scientists (myself included) are involved in seeking out biological ways to activate the same anti-aging pathway without having to deprive oneself of that slice of cake (remember Nobel Prize in the making).

Perhaps one day we will truly be biologically immortal and can eat our cake, too.

Amber Howard has been an assistant professor of biology at the University of Maine at Augusta since 2015. She is a 2011 Ph.D. graduate of Georgia Regents University, and recent postdoctoral researcher for the Mount Desert Island Biological Laboratory. She primarily focuses her research and teachings on physiology, disease mechanisms, and the biology of aging.

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Living Immortality, Russian Economy in 2017, How Big Is Russia’s Inequality Gap, and the Kremlin’s Risky Plans – Institute of Modern Russia

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In this weekly media highlights, Alexander Rubtsov reflects on the sad state of affairs in the Russian show business; Andrei Movchan offers his outlook for the Russian economy in 2017; Meduza fact-checks Alexei Navalnys presidential program; Valery Solovey shares his insights on the countrys political developments; and Peter Topychkanov discusses the Kremlins potential response to Donald Trumps nuclear initiatives. If you are interested in receiving this weekly roundup in your mailbox every Friday, let us know at info@imrussia.org.

One of Russia's most recognized pop-singers Philip Kirkorov who gained popularity in early 90s performs at the New Year's Night show at Channel One. As some experts observe, the fact that there are very few new faces in the country's show business reflects the general conservation trajectory in society. Photo: Dmitry Serebryakov / TASS

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Nathan Andrews helped compile this week's roundup.

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Living Immortality, Russian Economy in 2017, How Big Is Russia's Inequality Gap, and the Kremlin's Risky Plans - Institute of Modern Russia

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There Is No Such Thing as Alternative Medicine – Big Think

Posted: at 8:07 pm

If you want to sell an idea an opponent is helpful, especially if what youre selling cannot stand on its own merit. For example, homeopathy creator Samuel Hahnemann had trouble proving his provings offered anything beyond a placebo response. Given his reservations against the medical industrymany complaints were crediblehe dubbed any treatment offered by the conventional system allopathic.

Unfortunately for Hahnemann his philosophythe less of an active ingredient remains the more powerful a remedy is (once you reach 13c on the homeopathic scale there is no longer any active ingredient left)is nonsense. While today homeopaths still use allopathic as a derogatory sleight against mainstream medicine, theyre only shadowboxing an invisible enemy.

Alternative medicine, which includes homeopathy as well as vitamin and supplement companies and a number of other therapeutic modalities, is a $34 billion a year industry. While these companies enjoy the fruits of loose, and in many cases non-existent, regulations, their argument against allopaths is not the cry of the oppressed, but the desperate pleas of businesses concerned with their bottom lines.

Medicine is medicine. As pediatrician Paul Offit writes,

Theres no such thing as conventional or alternative or complementary or integrative or holistic medicine. Theres only medicine that works and medicine that does not.

This does not stop the irrational stream of unproven (or disproven) therapies arising from the holistic and wellness sphere. While pharmaceuticals and the companies producing them have their own problems, the rigorous standards of multiple trials, years of development and research, and millions of dollars spent are absent in the vitamin aisle of Whole Foods.

Yet many pharmaceuticals are based on similar or even the same botanical substances. At a public hearing on homeopathic product regulation on April 20, 2015, Adriane Fugh-Berman, an associate professor in Georgetowns Department of Pharmacology and Physiology, points out that homeopathic remedies can contain snake venom, heavy metals, controlled substances, [and] glandular extracts that would be considered dangerous if subject to federal regulation.

She points out that Guna Interleukin 12 is labeled for usage as a pain reliever and anti-inflammatory agent for autoimmune disorders. The remedy contains ingredients usually placed under intense scrutiny when used by pharmaceutical companies, but since the producer, Guna Interleukin Remedies, sidesteps regulation by utilizing the homeopathic loophole, consumers are ingesting potentially dangerous dosages.

When I asked the FDA why this oversight exists, press officer Lyndsay Meyer referred me to her agencys regulations, which refer to the unique nature of these drug products. Thanks to an amendment in 1983, homeopathic drugs are exempt from the requirement for laboratory determination of identity and strength of each active ingredient prior to release for distribution.

Hahnemann believed the less of a substance in the remedy, the stronger it is. Thus a partially diluted proving is not that strong while one containing no active ingredients is very powerful. Problem is, active ingredients matter. A recent report notes that one homeopathic teething pill resulted in more than 370 adverse reactions in children over a ten-year period.

This supposedly weak remedy is labeled 6X, meaning some of the active ingredients remains. One ingredient, Belladonna, is diluted at 12X (still active in mixture), which has a series of side effects, including GI infections and blockage, increased high blood pressure, and increased fever.

As Offit reports, 50 percent of Americans use alternative medicines while 10 percent give it to their children. While the FTC stepped in last year to plug a regulatory hole in homeopathic labeling, the legalese used by vitamin and supplement makers is confusing to consumers who read the large type on bottles and think their flu symptoms will be alleviated or, worse, that chelation cures cancer.

As health and wellness are wrapped into the fitness industry the science is only getting more confused. Just yesterday I walked by a center in Santa Monica that offers aerial silk and yoga classes, massage therapy, and IV vitamin drips. For $175 an hour you can have high doses of vitamin C, zinc, and lysine pumped into your bloodstream after Pilates, even though elevated levels of all three of those substances can cause numerous gastro-intestinal problems. Distrust in one doctor should not imply blind faith in another.

While supplements, vitamins, and superfoods are touted as cancer-fighting, antioxidant-boosting wonder drugs, the science is less enthusiastic. Offit writes,

Studies have now shown that people who take large quantities of vitamins and dietary supplements with antioxidant activity are more likely to have cancer and heart disease and die sooner.

Hahnemann helped inspire a holism movement championing Hippocratic philosophy during an important transition in medical history. The emergence of biochemistry, neuroscience, germ theory, disease specification, and molecular genetics made the invisible world visible. Widespread usage of antibiotics and vaccines offered humans an evolutionary thrust forward in biological knowledge. Suddenly a hostile planet became that much less daunting.

Yet a growing suspicion of corporate and political interests in the sixties inspired a new wave of holism thats gaining strength a half-century later. Were right to be wary of corporate agendas and political mismanagement when it comes to healthcare. Still, this does not excuse an entire industry pimping products with little to no scientific backing thats taking advantage of regulatory loopholes.

The reality is the most basic advicemove often and diversely; eat a balanced, whole foods dietis boring in an age of immediate gratification. People would rather sprint with a wonder-pill than put their head down for a marathon, and too many charlatans are stepping in to pretend theyve developed that pill.

As Offit concludes, theres a problem when we celebrate Suzanne Somersa saleswoman and industry unto herselfwhile only occasionally acknowledging the groundbreaking work of Siddhartha Mukherjee, a biological scientist, physician, and Pulitzer Prize-winning author. There are many incredible men and woman devoted to finding medicine that works. The alternative is suffering, something many companies and hucksters willfully champion at a time when we can all use less of it.

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Derek's next book,Whole Motion: Training Your Brain and Body For Optimal Health, will be published on 7/4/17 by Carrel/Skyhorse Publishing. He is based in Los Angeles. Stay in touch onFacebookandTwitter.

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Potential dangers and dubious history of alternative medicine are often unknown to its consumers – MinnPost

Posted: at 8:07 pm

Anyone who uses homeopathy, acupuncture or other alternative over-the-counter therapies particularly if they use them on their children needs to read two recently published articles on the topic.

One of the articles, published last week in the Boston Globes health website STAT, takes an in-depth look at the incredibly troubling story behind a popular homeopathic teething product that harmed hundreds of children in the United States before it was finally pulled from the market last fall.

The U.S. Food and Drug Administration (FDA) is currently reviewing the cases of eight babies who died after taking the product.

The other article, published earlier this year on the Science-Based Medicine website, describes the rise of traditional Chinese medicine (TCM) in both China and Western countries. It describes how TCM began as the dream of Chairman Mao Zedong back in the 1940s, but is receiving a renewed global push this year by the current Chinese government, in part to cover up major failings in Chinas medical system, but also to protect the profits of the countrys multibillion-dollar traditional pharmaceutical industry.

Both articles underscore how people often abandon their skepticism and their reason to embrace bogus alternative-medicine practices that are not only a waste of time and money, but also potentially harmful.

The articles also rip apart the prevalent David-and-Goliath myth regarding alternative therapies: the idea that alternative-medicine manufactures are small, noble companies who only want to bring inexpensive, natural remedies to people in need, but who find themselves battling the big, bad profit-driven pharmaceutical industry.

The truth is much less attractive: Alternative medicine is now a huge profit-driven, multibillion-dollar industry, too. And parts of it are owned by the pharmaceutical industry.

For the STAT article, reporter Sheila Kaplan used the Freedom of Information Act to seek and review FDA records for homeopathic teething pills marketed by Hylands, a 114-year-old private, Los-Angeles-based company that sells more homeopathic products than any other company in the U.S.

A review of those records revealed that during the 10-year period 2006-2016 the FDA received reports of 370 children who had experienced adverse health events after using Hylands homeopathic teething tablets or gel. The reports are grim, says Kaplan:

Babies who were given Hylands teething products turned blue and died. Babies had repeated seizures. Babies became delirious. Babies were airlifted to the hospital, where emergency room staff tried to figure out what had caused their legs and arms to start twitching.

Medical experts believe toxic levels of the teething tablets main ingredient the herb belladonna may have poisoned the children.

Despite those reports, it took four years until the FDA pushed Hylands to reformulate its remedies, writes Kaplan. And even after that reformulation, there was a steady stream of reports of adverse events tied to Hylands homeopathic teething products, she adds.

The Hylands teething tablet saga raises issues that most consumers of homeopathic and other alternative therapies are unaware of, as Kaplan explains:

Homeopathy has become a multibillion-dollar industry. Its products are big sellers around the world, and popular with adherents from Cher to Prince Charles. The industry also has political clout: It has been able to exempt itself from many rules proposed by Congress and the FDA over the years.

Unlike pharmaceutical company-produced drugs, homeopathic products dont have to prove that they are effective at treating anything in particular before going on the market. It is left to the FDAs drug division to determine whether they are unsafe after they are on the market a difficult task since the adverse event reports are generally considered to represent only a fraction of the actual incidents and may lack sufficient information to allow for thorough investigations.

In some cases, parents assume that products described as natural remedies, as is the case with Hylands tablets and gels, could not possibly result in complications, and never mention their use to a doctor. Without sufficient evidence of a problem, the FDA lacks what it needs to use the enforcement tools it does have.

Hylands has stopped making its teething tablets, but only after the FDA recommended last September that consumers not use the product (or other homeopathic teething products) while the agency investigates more cases of possible serious reactions among babies.

Kaplan tells a harrowing story in her article one all users of homeopathic medicines would be wise to read.

The Science-Based Medicine article also contains background information that is likely to surprise most consumers of another arm of alternative medicine TCM. Acupuncture is by far the most popular TCM therapy, at least in Western countries, but TCM includes many other treatments, include herbal medicines.

As Dr. David Gorski, a columnist for Science-Based Medicine and a surgical oncologist at the Barbara Ann Karmanos Cancer Institute, explains in the article, acupuncture has been appropriately described as a theatrical placebo, with no detectable difference in effect compared to sham or placebo acupuncture.

Furthermore, acupuncture is not even ancient, as Gorski explains:

The technology to make such thin needles didnt exist two thousand years ago, [and], as recently as a century ago, acupuncture was brutal and primitive, using nothing like the thin, shiny needles acupuncturists use today.

But the problem with TCM, he says, is not just acupuncture, its the whole ancient, prescientific system of medicine.

Take Chinese herbal medicines. Even if the herb itself is innocuous (and not all are), medicines imported from China have been found to contain undeclared ingredients, including pesticides, heavy metals (such as lead and arsenic), antibiotics, decongestants and the DNA of endangered snow leopards. (Animal parts, including those of endangered animals, are often used in traditional Chinese medicines, says Gorski.)

The presence of toxic materials in these medicines is not a minor matter. Recent studies have suggested that herbal medicines are the leading cause of drug-induced liver failure in China and other countries where TCM is rapidly becoming popular, such as South Korea and Singapore, Gorski points out.

Like other forms of alternative medicine, TCM is built on a myth. Gorski explains:

[T]he exportation of TCM to the world was quite deliberate, as part of a strategy [by the former Communist leader of China, Mao Zedong] to popularize it among the Chinese. There was a problem, however. There was no such thing as traditional Chinese medicine per se. Rather, there were traditional Chinese medicines. For many centuries, healing practices in China had been highly variable. Attempts at institutionalizing medical education were mostly unsuccessful and most practitioners drew at will on a mixture of demonology, astrology, yin-yang five phases theory, classic texts, folk wisdom, and personal experience.

Mao realized that TCM would be unappealing to foreigners, as even many Chinese, particularly those with an education, understood that TCM was mostly quackery. For instance, in 1923, [the Chinese writer] Lu Xun realized that Chinese doctors are no more than a type of swindler, either intentional or unintentional, and I sympathize with deceived sick people and their families. Such sentiments were common among the upper classes and the educated. Indeed, Mao himself didnt use TCM practitioners. He wanted scientific Western medicine. The same was true of educated Chinese. It still is. TCM is far less popular among educated middle class and affluent Chinese than conventional medicine.

Yet that hasnt stopped the current Chinese government from passing a new law, which goes into effect in July, that mandates the integration of Chinese and Western medicine throughout their country.

The purpose of the law, says Gorski, is to elevate the status of TCM to the equivalent of Western medicine and thus provide a cheaper way of delivering medicine to Chinas overrun medical system.

One also cant help but notice that a lot of this new law goes towards protecting the business interests of the TCM industry in a manner that, if it were done for the pharmaceutical company, would provoke howls of outrage from [alternative medicine] proponents and rightly so, writes Gorski.

FMI: You can read Gorskis article on the Science-Based Medicine website. Kaplans can be found at the STAT website.

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What your family needs to know about IV vitamins – Deseret News

Posted: at 8:06 pm

Grammy Award winner Adele says she gets some of her sparkle from an infusion of vitamins delivered through an IV. Intravenous vitamins are a relatively new twist in America's love affair with nutritional supplements, but are they any different from those that come in a bottle?

Probably not, some health experts are saying, and others say we don't need supplements at all. But that's not stopping Adele and other celebrities from submitting to the needle, turning IV vitamins into the latest wellness trend by their glittering example.

The appeal of IV vitamins is that of other supplements: the promise of beauty, health and zest, delivered faster than food, absorbed more fully than a pill.

In recent years, however, the Food and Drug Administration has warned that a vitamin C solution administered by IV is not a high-tech vitamin, but an unapproved drug that can be dangerous. And it's definitely not for children. Here's what you and your family should know about the craze.

A drip of wellness?

Adele accepts the award for album of the year at the 59th annual Grammy Awards on Feb. 12, 2017, in Los Angeles. Adele says she gets some of her sparkle from an infusion of vitamins delivered through an IV. | Matt Sayles, Invision

The Hollywood Reporter says that Adele, the British singer who swept the Grammy Awards in February, goes to a wellness spa in Los Angeles that charges $220 for an IV energy infusion called "Limitless." The spa Drip Doctors and others that offer vitamin infusions say that 95 percent of liquid vitamins injected into a vein are absorbed into the body, compared to 20 percent of vitamins taken orally.

There's something to this reasoning, but for increased absorption, you don't have to use an IV. Taking vitamins or medicine in liquid form makes them available to the body faster than taking a pill, which has to be broken down by the body.

A person who gets vitamins by IV, however, risks complications ranging from dizziness, nausea or death if the dosing is wrong, Kathryn Romeyn wrote for The Hollywood Reporter, which is why it's important that the drip be administered by a doctor. Even in hospitals, one in five patients hooked to an IV suffered complications or died because of "inappropriate administration," a 2013 British study concluded.

Dr. Svetlana Kogan, a New York physician, told Romeyn that she recommends intravenous vitamins only for people who have an ongoing medical problem such as chronic fatigue syndrome or fibromyalgia, or if they are frequently sick or need to boost their immune system before traveling.

"People should not be using IV therapy frivolously," Kogan said.

Two board-certified anesthesiologists are part of the staff at The Vitamin Bar, an intravenous vitamin spa with offices in Salt Lake City and Park City. Its website promises 100 percent absorption and says vitamin therapy will leave you with an "overall feeling of health and wellness."

The business recommends that clients have two to four "drips" each month, and offers special formulas for hangovers, jet lag and altitude sickness, as well as pregnancy, skin hydration, memory and hair and nail health. Clients must be 18 or older.

Other than being more expensive, are intravenous vitamins any different from those that come in a bottle? | Adobe Stock

"At the end of a drip, most of our clients say they feel invigorated, full of life, and ready to tackle the rest of their day," The Vitamin Bar website says.

Treatments that cost $139 include "The Hippocrates," for people recovering from "a paper cut or major surgery," and "The Centennial," for people who want to live past 100.

Getting life-boosting fluids from IV lines, despite the current craze, is nothing new. As early as the 1600s, doctors knew that medicine could be injected into the vein, and an Oxford scientist of that time period created an intravenous device using a pig bladder and a quill, and he practiced on a dog that was given opium, according to an article in the British Journal of Anaesthesia.

Today, the IV is the most common procedure done in emergency rooms, with one-quarter of patients receiving IV fluids, according to the CDC. And commercial IV clinics for hydration have been around for several years; one opened in Chicago in 2012, and it was soon followed by at-home IV hydration and mobile IV hydration offered to runners at road races. Runner's World magazine examined the service, and while the article quoted runners who said they felt "amazing" after getting fluid intravenously, the writer cited studies that said the difference between getting an IV and drinking fluid was "negligible."

The company mentioned in the Runner's World article, Onus IV Hydration, is based in Denver, and it credits the late Dr. John Myers, a Baltimore physician, with inventing a nutritious IV cocktail of magnesium, calcium and B and C vitamins 30 years ago. Its treatments range from $65 for simple saline hydration to $145 for Myers' original concoction, said to "supercharge the system and enhance overall wellness."

The treatment can be delivered to your home or office by a nurse with a duffel bag, or, at larger events, in a Mercedes Sprinter van, and the procedure takes 30-45 minutes, with effects felt within an hour. A doctor is not usually present, but is available by phone for questions, the company's website says.

In search of evidence

Critics of nutritional IVs are not just people who raise questions about the risks of the procedures, but those who doubt vitamins and other supplements are useful at all. In an article in STAT, Megan Thielking skeptically examined the Manhattan IV clinic run by Dr. Erika Schwartz and said there isnt any "robust evidence" that shows infusions have any effect beyond that of a placebo.

Thielking quoted Dr. Pete Miller, a clinician and nutrition researcher at Johns Hopkins, who said, "Supplements dont fix anything and they dont prevent anything. Its simple."

The American Academy of Pediatrics says healthy children who eat a "normal, well-balanced diet" do not need vitamin supplementation and that megadoses can be toxic.

Vitamin D tablets are displayed on Nov. 9, 2016, in New York. | Mark Lennihan, Associated Press

There are exceptions: For example, most newborns receive a vitamin K injection, and doctors often recommend that breastfed babies be given vitamin D.

If children are finicky eaters, doctors often recommend a multivitamin, and certain health conditions might require supplements for example, a new study from the University of Massachusetts Medical School recommends vitamin D supplementation for children with irritable bowel syndrome.

For adults, the advice is similar. In its dietary guidelines, the U.S. Department of Agriculture urges people to get their vitamins through food and beverages, but the Food and Drug Administration says that people may need them if they have health problems, eat a vegetarian or vegan diet, or are pregnant or breastfeeding.

Most spas, however, market IV vitamins not to sick people, but to people seeking extreme health.

Schwartz, the author of "Don't Let Your Doctor Kill You," treats celebrities and jet-setters who pay from $325 to $875 for a treatment at her clinic, Evolved Science. Results, the website says, include increased energy, improved mood, diminished jet lag and improved athletic performance.

We put together the ideal combination for them to obtain the results they want: clearer skin, clearer mind, better hair, better nails, Schwartz told Thielking.

Another clinic, this one in Los Angeles, offered a special infusion for Valentine's Day, touting its aphrodisiac effects.

For people who don't like shots and needles, or sitting around for a half-hour or more to take their vitamins, there are always gummies, capsules or pills. And an Arizona company has developed vitamins you spray in your mouth.

Or, you could just eat things. As the celebrated food writer Michael Pollan says, for optimal health, "Eat food. Not too much. Mostly plants."

Water helps, too.

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RIBUS Earns Non-GMO Project Verification for Bev, Food, Pet … – PR Web (press release)

Posted: at 8:06 pm

Non-GMO Project Verified

St. Louis, MO (PRWEB) February 28, 2017

Leading ingredient supplier RIBUS, has earned the Non-GMO Project Verified status for its rice-based natural and organic alternatives to synthetic ingredients. Its products - Nu-BAKE, Nu-FLAC, Nu-FLOW, and Nu-RICE, - are widely used to replace synthetic ingredients such as silicon dioxide and magnesium stearate in the food, beverage, pet, and dietary supplements sectors. While all US rice is non-GMO, the growing consumer interest in non-GMO products plus the number of companies requesting the seal to avoid international prohibitions on GMO ingredients made the Non-GMO Project Verified certification a natural choice.

Use of RIBUS ingredients enable companies to remove chemistry lab-sounding words and provide clean label terms such as rice extract to consumers, while enabling the same functionality and quality, says Steve Peirce, RIBUS president. Gaining the Non-GMO Project Verified seal serves as an additional stamp of approval that best practices for GMO avoidance are used whether for our natural or organic ingredients.

Nu-MAG is the newest addition to the RIBUS portfolio. Last fall, the company launched the ingredient which can replace magnesium stearate and stearic acid, synthetic ingredients previously considered vital in making dietary supplements, but prohibited in organic products. Nu-MAG provides tablet and capsule manufacturers the required lubrication, while also enabling clean label statements. The ingredient is being tested by companies in the US and around the world, and is in the process of gaining the Non-GMO Project Verified certification.

RIBUS saw continued double-digit growth company-wide in 2016, with particularly rapid growth in the dietary supplements sector. To accommodate that growth, the company hired Steve Dybdal as RIBUS Supply Chain Manager. Dybdal has over 15 years of dietary supplement experience in production, formulations, and operations management with a leading nutraceutical contract manufacturer.

The RIBUS team is attending both the March 8 SCIFTS Suppliers Night Expo (booth 1311) in Anaheim, CA, as well as Engredea(booth 530) March 8-12. In addition, Steve Peirce will present on the Natural Products ExpoWest panel, "Innovation in Clean Label Formulations," Wednesday, March 8, at 11:45 a.m. in the Marriott Grand Salon G.

RIBUS will also be speaking and/or exhibiting at the following events in 2017: 1.Petfood Forum in Kansas City, MO. April 3-5 2.VitaFoods Europe Geneva, Switzerland. May 9-11 3.IFT Las Vegas, NV. June 26-28 4.Supply Side West Las Vegas, NV. September 27-28 5.Food Ingredients Europe Frankfurt, Germany. November 28-30

About RIBUS: St. Louis, MO-based RIBUS is the global leader in natural and organic rice-based alternatives to synthetic ingredients. The company produces non-GMO, natural, organic, vegan, and gluten-free ingredients, and its team of brokers and distributors includes over 100 sales representatives around the world. RIBUS is a member of the Organic Trade Associations Organic Supplements Council.

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RIBUS Earns Non-GMO Project Verification for Bev, Food, Pet ... - PR Web (press release)

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All Natural Supplements Pitched on Shark Tank – Ora Organic – Huffington Post

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The second entrepreneurs into the Shark Tank this week presented their business Ora Organic and were seeking $375k in exchange for 5% of the business. They have developed a line of all-natural supplements that can be taken or used in cooking. They also talked about their plans to start selling pre-made food that uses their supplements.

As for their numbers, they saw over $400k worth of sales in under 10 months. They have also taken a $150k note at a $2.2Mill valuation.

When the Sharks started to weigh-in it started off well, but then went downhill pretty fast. They liked the samples and food that the entrepreneurs gave them, but all started giving their reasons for dropping out pretty quickly. Robert said its just not the product for him, Daymond said that their valuation was insane, Lori did not like the branding on their packaging, and Mark said that he thought they were selling food made from the supplements and isnt interested since theyre not.

Kevin did want to make them an offer though. He started at $375k in exchange for 20%, but after a few counters he came down to 17%. This was still not the valuation that the entrepreneurs were looking for, so they decided to walk without a deal.

I can actually agree with some of the Sharks thoughts on this product. First of all, there is a lot of competition in this space, so that makes it a fairly risky investment. With that in mind, putting their value at $7.5Mill this early on is a bit optimistic and doesnt ease the worries that the Sharks might have about the risk. As well, still on the topic of competition, I can definitely understand Loris worry about the packaging. It was minimalistic and clean, but thats not what you want on the shelves of a store when youre probably one of twenty different brands sitting there. Im not advocating big, bold, and tacky branding, but there are ways to better design that packaging to draw a persons eye to their product.

Beyond simply responding to the Sharks thoughts though, I dont have much more to add on this one. I have never been interested in supplements of any kind and I dont know much about them at all. I mentioned in a previous article that I have tried Nootropics before, but other than that my experience is limited.

Anyway, good luck to Ora Organic! Im excited to see what kind of food you guys start selling alongside the supplements! I think that will be an excellent vehicle for growth in the business.

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