Daily Archives: February 7, 2017

NASA Langley Ozone Sensor Set for Launch to Space Station – Space Daily

Posted: February 7, 2017 at 9:55 pm

Brooke Thornton has devoted eight years to a project that aims to check on the atmospheric health of the Earth. Needless to say, when NASA's Stratospheric Aerosol and Gas Experiment III on the International Space Station (SAGE III on ISS) launches, she'll be among the many cheering and working for its success in space.

"After seeing SAGE III mature from concept, to development, to assembly and testing, and preparing for mission ops ... I'm excited to see it launch so we get the science we have worked so hard for," she said.

Thornton, of NASA's Langley Research Center in Hampton, Virginia, is the mission operations manager for SAGE III on ISS, which is a key part of NASA's mission to provide crucial, long-term measurements that will help humans understand and care for Earth's atmosphere.

The instrument measures Earth's sunscreen, or ozone, along with other gases and tiny particles in the atmosphere called aerosols. SAGE makes its measurements by looking at the light from the sun or moon as it passes through Earth's atmosphere at the edge, or limb, of the planet.

The result is a thin profile of the atmosphere from the unique vantage point of the space station, which has an orbit ideal for SAGE measurements.

Thornton and her operations team will look after SAGE III once it is attached, via robotic arm, to the station - operating the payload remotely from the ground "to get the best science," she said.

'Humble beginnings' The first SAGE instrument began operations in space on Feb. 18, 1979, following a 1975 proof-of-concept experiment called the Stratospheric Aerosol Measurement (SAM) on the Apollo-Soyuz mission.

SAM, the first experiment of its kind conducted from space, proved the value of a technique called occultation. Through that method, scientists identify components of the air by studying sunlight as it beams through the upper edges of atmosphere and comparing it to light coming straight from the sun, with no atmosphere in between. SAM was followed by SAM II and then the SAGE instruments.

"Since those humble beginnings, scientists and the engineers here at NASA Langley have perfected the technique," said Michael Cisewski, project manager for SAGE III on ISS.

SAGE II was a part of the Earth Radiation Budget Satellite (ERBS) and was deployed by the crew of space shuttle Challenger in 1984. It operated and produced data for more than 21 years.

The first SAGE III was launched in 2001 on a Russian satellite, Meteor-3M while another SAGE III was safely stored away. After several years of storage and preparation for the current mission, the SAGE III payload was shipped from Langley to NASA's Kennedy Space Center in Florida, in November 2015, ready for launch, currently targeted for February from Kennedy on a SpaceX Falcon 9/Dragon Vehicle.

Upon arrival to the space station, the instrument will be robotically installed onto an ExPRESS Logistics Carrier (ELC) platform, ELC-4 to be exact, using the space station's primary robotic arm, Canadarm2.

"The station robot arm removes SAGE III from the Dragon trunk, and then rides along the ISS truss to our mounting location and then installs the payloads," Thornton said. The system is really amazing. The ISS robotics system is completely controlled from the ground, saving precious crew time needed to perform on-board science."

After meticulously checking out all payload systems and initial calibration and validation, SAGE III will begin taking routine science measurements. The data is downloaded daily to the ground for use by the international science community.

While it was led at NASA Langley Research Center, the project has many partners both within NASA and with private companies in the United States and internationally. Three NASA centers - Kennedy, NASA's Johnson Space Center in Texas and NASA's Marshall Space Flight Center in Alabama - contributed to the project as well as Ball Aerospace and Technologies Corp. in Boulder, Colorado, the European Space Agency and Thales Alenia Space-Italia.

All about the data The SAGE data-collecting missions helped inform political actions on Earth. On Sept. 16, 1987, an international treaty, known as the Montreal Protocol, was signed by most nations of the world. The agreement called for phasing out production of many of the substances that were responsible for ozone depletion. The treaty has been in force since Jan. 1, 1989.

"The SAGE instruments showed the world that we were losing stratospheric ozone globally," said Joseph Zawodny, project scientist.

"The world did an amazing thing by limiting the chlorofluorocarbons through the Montreal Protocol," Thornton said.

The Intergovernmental Panel on Climate Change, a scientific organization under the auspices of the United Nations, announced in 2005 that their observations of the stratosphere showed that the global amount of ozone is stabilizing. The IPCC study indicates that the atmosphere layer is expected to begin to recover in coming decades under the current ban on ozone-depleting substances continues.

Earth-observing instruments like SAGE III that monitor climate and ozone levels are a key part in looking after the health of the Earth and can help spur positive changes. The SAGE flight on ISS now will provide key data letting scientists know if the ozone layer is on track to recover as predicted by current models.

"When you're working on a project with so many moving part like this, it can be difficult to appreciate how important it is or what kind of impact your work will have," Cisewski said. "SAGE III is not just important to Langley or the United States - it's important to the world."

Getting set for space This version of the SAGE instrument is equipped with powerful tools. The instrument uses a telescope, a grating spectrometer and a charge coupled device detector array that, together, act as a sophisticated camera.

"The combination of SAGE instrument capabilities and the solar occultation measurement technique make the instrument essentially self-calibrating," Thornton said. "The SAGE instrument has been called the gold standard for all other instruments that are looking at ozone."

Since the instrument arrived at Kennedy from Langley, engineers have assisted SAGE team members in preparing it for launch.

"We have such an amazing mission ops team that I'll be working with," Thornton said. "It's a very tight group and I think that will improve the quality of the data that we get."

"I am proud of what our team has accomplished," Cisewski said, adding it's like a family. "The team has been really first-class and put in the extra efforts to make SAGE a big success."

Cisewski will be on-site at Kennedy when SAGE launches, and will be watching with pride.

"We're doing our part to go ahead and provide the best data set for people that are trying to make decisions now," he said. "This data is going to be useful 50 years from now."

Those thoughts were echoed by Thornton.

"SAGE instruments have shown the whole story so far of ozone trends," she said. "Now, hopefully this instrument will be able to show the recovery of the ozone."

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VIDEO: Astronaut Tim Kopra Throws Football 564664 Yards Aboard International Space Station – SpaceCoastDaily.com

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ball was covering about 8,800 yards per second

ABOVE VIDEO: Astronaut Tim Kopra gently tossed a football down the length of the station, the ball was technically covering about 8,800 yards per second (8046 m/s) as measured by someone standing on Earth.

(SPACE) Has a NASA astronaut set a new record for the longest football pass in history? A new video shot in orbit aboard the International Space Station captured the incredible feat.

The space station orbits the Earth at a speed of about 17,500 mph (28,163 km/h). Therefore, when astronaut Tim Kopra gently tossed a football down the length of the station, the ball was technically covering about 8,800 yards per second (8046 m/s) as measured by someone standing on Earth.

In total, the ball traveled 564,664 yards (516,328 meters), according to the video, and NASA posed the question, Is this a new world record?

Were guessing that Guinness World Records will not grant Kopra the record, considering that he too was traveling at an incredible speed when he threw the ball.

Kopra returned home from his latest trip to the orbiting laboratory in June 2016, so it seems NASA has been holding on to this potentially record-setting footage for a while, and chose to release it ahead of the 2017 Super Bowl this Sunday.

NASA made its presence known at this years Super Bowl in Houston, home of the Johnson Space Center.

Leading up to the big game, visitors to Houston were able to check out a free festival taking place at Discovery Green, located in the citys downtown area.

The main attraction there was a virtual reality roller coaster, called Future Flight, which simulates a spacecraft landing on Mars.

The free festival featured displays, booths and activities created by NASA, as well as by private spaceflight companies, including Boeing, Aerojet Rocketdyne, Lockheed Martin, Northrop Grumman, Orbital ATK and Raytheon.

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Space Station sendoff finally arrives for Buffalo’s young ‘Spud … – Buffalo News

Posted: at 9:55 pm

When you take a glance at the night sky in the coming weeks, think about the "Spud Launchers" the three budding scientists from Buffalo, whose potato experiment will be orbiting up there somewhere inside the International Space Station.

The three Buffalo Public School students Gabriella Melendez, Toriana Cornwell and Shaniylah Welch will travel to Cape Canaveral, Fla., next week to watch the launching of the rocket that finally will carry their science experiment to the space laboratory.

The honor was bestowed upon the girls in 2015, when they were among the winners of a national science competition sponsored by the National Center for Earth and Space Science Education. The education center partners with NASA and NanoRacks, a leader in the commercial space industry, to inspire the next generation of scientists and space explorers.

The three girls who attended Hamlin Park School 74 together will test whether 20 tiny potatoes squeezed into a small, half-inch tube can survive space travel. Upon return to earth six weeks later, their experiment will be returned to them for planting inside a University at Buffalo greenhouse.

It's an area of interest, particularly with NASA cultivating the ability to grow food in space in preparation for longer space missions and hoping maybe one day to plant the crop in a controlled dome on Mars.

The rocket launch was supposed to happen last spring, but the three girls have been waiting patiently Toriana and Shaniylah are now in high school as a number of delays pushedback the mission to this month, said Andrew Franz, the Hamlin Park teacher who served as an adviser for the project.

Their experiment already has been shipped off in preparation for the launch and thanks to donations, the girls who call themselves the "Spud Launchers" will be there to watch. They'll head to Florida and be thereFeb. 13-16 with Franz, school Principal Patrick Cook and Ina Ferguson, liaison for WNY STEM Hub.

WNY STEM Hub, which coordinated the competition locally, is a nonprofit created to steer students toward the fields of science, technology, engineering and mathematics.

"It's a huge relief for the girls," Franz said. "We already put our tube with the potatoes in the mail and we won't see them again until March or April."

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6 Classic Sci-Fi Stories That Inspired This Week’s Supergirl – Paste Magazine

Posted: at 9:54 pm

With a title like The Martian Chronicles, it probably wont surprise you to learn that sci-fi referencesboth intentional and not-so-intentionalabound in last nights Supergirl. Like most good science fiction writers, the Supergirl team builds on the theories and established conventions of past authors. Lets take a look at the works that inspired this weeks episode:

1. The Martian Chronicles Lets start off with the most obvious reference: a title borrowed from one of Ray Bradburys best-known works. Bradburys The Martian Chronicles is a classic of science fiction writing, detailing the human exploration and colonization of Mars. Told as a series of connected short stories, Bradbury uses the setting of Mars and the human desire to escape from a dying Earth to explore a lot of contemporary themes. Written in the late 1940s, Bradbury bluntly explores themes like racism, colonization, nuclear war and death, all while ruminating on what it means to be human. Its powerful work and far from uplifting, butwithout detailing any spoilersits well worth a read, especially if youre a believer in the idea that science fiction gives us a space to talk about the less savory aspects of human nature.

2. Invasion of the Body Snatchers Are your friends and loved ones acting strangely? Are they acting a bit too much like themselves? Are they too understanding, too calm, too patient, too willing to listen to you whine about how theyve let you down without defending themselves? Bad news, my friend: Theyve been body snatched.

The Invasion of the Body Snatchers franchise encompasses several movies, thematic connections to multiple authorsincluding Robert Heinlein, whose 1951 novel The Puppet Masters provided the loose inspiration for the film versionand even a Bugs Bunny cartoon. (Its called Invasion of the Bunny Snatchers, and its perfect.) All revolve around the paranoia that the people we know could one day be replaced by identical alien life forms with no discernable difference. So when Mgann, Winn, and later Alex turn out to be white Martians in disguise, those feelings of uncertainty and paranoia come straight out of the Body Snatchers bag of tricks.

Originally meant as a metaphor for communism and the Cold Warand, really, when was anything not originally meant as a metaphor for communism and the Cold WarSupergirl ups the ante on Snatchers by taking a more personal route. Its a horrifying idea: That you could be spilling your most difficult-to-process and embarrassing feelings to a person you think is your closest friend, only to find out that the person literally isnt who you think he is. Try hard not to think about it the next time youre talking to your crush.

3. John Carpenters The Thing Basically, any media artifact in which a group of badasses is trapped in an isolated settingin Supergirls case, well count the lockdown as isolatedwhile trying to figure out who may or may not be an alien owes its dramatic tension to The Thing. Throw in a liberal use of fire as both a test and a weapon, and you have a pretty safe guess as to what movie the Supergirl writers were watching while writing last nights episode.

4. The Twilight Zone The Twilight Zone had something of a crush on Mars upon its debut in 1959. When space invaders were needed or far-off planets explored, The Twilight Zone usually found itself on Mars. (Well, except that one time where they found a giant mouse on the moon. But we try not to think about that.)

Its no surprise then that the seminal sci-fi TV series put into practice most of the space exploration tropes we see todaya list worthy of its own article, to be sure. Still, one of the best, invoked in tonights Supergirl, comes from the classic episode Will the Real Martian Please Stand Up? (Spoilers ahead. Consider yourself warned.) In it, two police officers investigate the crash of what appears to be an alien space ship, tracking the survivor to a diner where a bus full of travelers has stopped for a meal. Its a classic paranoia plot, in which the cops try to determine which of the passengers is the alien in disguise. The plot relies on a lot of misdirection, but its ultimately revealed that the unassuming man in the corner was a three-armed Martian the entire time. Not content with this twist, The Twilight Zone then reveals that the kindly counter attendant (whose long-term job at the diner kept him above suspicion) is actually a three- eyed Venusian. There were two aliens all along! Luckily, in this case, neither turned out to be Supergirls sister.

5. Melbourne and Mars: My Mysterious Life on Two Planets Of all the references on this list, Id put good money on the fact that the Supergirl team had no idea they were alluding to Melbourne and Mars while working on the white Martian plot line. Written in 1889 by Joseph Fraser, the story details the life of a sick man named Jacobs living on Earth. As his health deteriorates, Jacobs begins to have dreams of an alien world. It is eventually revealed that these dreams are a telepathic link between him and a child, his other self, living on Mars. Thanks to series like the aforementioned Martian Chronicles, we take Martian telepathy as a standard in science fiction. So much so that, were Martians to exist, I suspect we humans would start an intergalactic war with some unintentional snark about their mind reading abilities. Still, Melbourne and Mars was the first fiction to speculate on this idea, and while maybe only a handful of people consider it a must-read today, it created one of the qualities we most closely associate with (speculative) alien life forms.

6. Casablanca Finishing off this weeks list is a classic, though its obviously not a work of science fiction. Mgann and Jonns struggle to express and come to terms with their growing love for one another has some overtones of Romeo and Juliet. Still, with its themes of war, longing and a desperate need to do the right thing, their tragic love story shares more in common with the Humphrey Bogart and Ingrid Bergman classic than any other. A reversal of gender roles adds extra punch here, with Mgann taking Ricks attitude that sacrificing peace and love for the greater good is necessary, and Jonn arguing that they can be happy if they just agree to hide from their problems together. Its unconsummated love, which, depending on your interpretation of Casablanca, they also share with Rick and Ilsa. Throw in Armek as an evil, less desirable, jerkface-who-needs-to-die version of Victor Laszlo and you have a feminist science fiction twist on one of the greatest films ever made.

Katherine Siegel is a Chicago-based writer and director, and a regular contributor to Paste. You can find out more by checking out her website or follow her on Twitter.

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Movie review: "The Space Between Us" is aimed squarely at teens – Anchorage Press

Posted: at 9:54 pm

The Space Between Us is apparently a large divide when it comes to describing this silly, romantic, mixed-up movie.

Its an interplanetary adventure as a science-fiction flick with a race against time.

Its a teen romance (involving a girl named Tulsa!) formed around a fish-out-of-water story.

Its a morality play, and its a redemption story.

Its a mess, more than anything, that goes from a convoluted, boring first hour to a second half that is such a heart-on-its-sleeve love story, aimed so squarely at tween girls, that your 12-year-old daughter may walk out of the theater swooning.

That may be the one group of people whose space between their ears will really appreciate The Space Between Us.

Initially set in the very near future, NASA sends a shuttle of astronauts to prep Mars for colonization, but theres a problem: One of them is pregnant. The baby is born on Mars, and the mother dies in childbirth.

That makes Gardner Elliott the first human not born on Earth, and that makes him different.

No. 1: A full gestation in zero-gravity atmosphere means his organs are different than our own, endangering his ever coming home.

No. 2: Sentencing him to live on Mars is a bit of a public-relations nightmare, so his existence is kept a secret from the public.

I know what some may be thinking, but no: The moon landing was not faked.

This whole snafu leaves Gary Oldman, as the architect of this Mars mission, fretting and yelling at people about this massive cover-up, and it leaves a motherless boy stuck with astronauts inside a small space station for the first 16 years of his life.

Asa Butterfield (Miss Peregrines Home for Peculiar Children) already proved his sci-fi teen mettle in Enders Game, and now as Gardner he gets an upgrade to romantic lead.

But it takes forever to get him there in the hands of director Peter Chelsom (Serendipity, Hannah Montana: The Movie).

Between Oldmans rants down on Earth, Mars mother-figure Carla Guginos sentimental concerns for the boy and Gardners repeated questions Whats Earth like? Whats your favorite thing about Earth? Will I know how to act on Earth? that the only thing that kept me from snoring was thinking out loud: When are you going to get this boy on Earth?

The movie never really takes off until we get Gardner in front of Tulsa, the teen girl in Colorado hes been secretly future-texting from Mars, where the wi-fi is red planet-hot.

Tulsa is played by Britt Robertson, who was the one good thing about Tomorrowland and who, at 26, is so pretty that she can make us believe shes still in high school.

It turns out that she was abandoned at age 4 in Tulsa, and the orphan girl adopted the city as her nickname.

So we can see that bond start to form: Both Gardner and Tulsa grew up without parents, forced to live with strangers who didnt always tell them the truth.

Butterfield brings an awkward, goofy, somewhat cute manner to his discovery of Earth things both large and small, from crawly bugs to homeless people to Robertsons lips.

Robertson, playing the street-smart girl who can steal a car as easily as she takes off in a crop-dusting plane, brings a blushing sweetness to her tough chick, whose defenses weaken in the presence of a true innocent.

After a sloooow-developing period of great length, its remarkable that the final act is as moving in a sappy kind of way as it is. Admittedly, my 12-year-old daughter may have coaxed that feeling along.

She and her friends are the audience for The Space Between Us, and those accompanying them will just have to grin and bear it.

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‘Amazing Stories of the Space Age’: Q&A with Author Rod Pyle – Space.com

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The Manned Orbiting Laboratory (MOL) is one of the space missions discussed in Rod Pyle's new book, "Amazing Stories of the Space Age," now on sale.

A new book brings together tales of the most bizarre and incredible space missions ever conceived. The book's author (and regular Space.com contributor), Rod Pyle, talked with Space.com via email about these amazing space missions and what they can tell us about the future of spaceflight.

The book, "Amazing Stories of the Space Age: True Tales of Nazis in Orbit, Soldiers on the Moon, Orphaned Martian Robots, and Other Fascinating Accounts from the Annals of Spaceflight," is now available in paperbackand as an e-book. You can read an excerpt of the book here.

"Amazing Stories of the Space Age: True Tales of Nazis in Orbit, Soldiers on the Moon, Orphaned Martian Robots, and Other Fascinating Accounts from the Annals of Spaceflight," by Rod Pyle.

Space.com: This book is a collection of stories about strange and amazing spaceflight missions and ideas for missions. To give our readers an idea of the kinds of things covered in the book, can you briefly describe one of your favorite "amazing storie," or one of the missions you find really fascinating?

Rod Pyle: I love them all, of course, but one that touches my heart is about the final days of the Viking 1 Mars lander. Two Viking spacecraft, each comprised of an orbiter and a lander, headed off to the Red Planet in 1975, arriving in 1976. After studying the surface from orbit, the flight controllers committed Viking 1 to a landing on July 20, 1976. They could only infer what the surface might be like from relatively low-resolution imaging, but they met with luck twice: first with this landing, and then with Viking 2 about six weeks. The folks at NASA's Jet Propulsion Laboratory (JPL) still marvel at the accomplishment. After a long and successful campaign of great science, one by one, the Vikings went dark, and by late 1982, only Viking 1 was still transmitting, sending daily weather reports to Earth. At six years into the mission, however, the lander was experiencing some battery issues similar to what had ended the Viking 2 landers mission. The programmer assigned to the mission wrote some new software to optimize the battery charging cycles and uplinked it to the lander, where it was dutifully recorded onto the computers tape-drive memory. Unfortunately, it overwrote an instruction set responsible for keeping the radio dish oriented toward the Earth, and the lander fell silent. JPL tried to regain contact for months, to no avail. The team was devastated. And because the lander had a nuclear power supply, we have no idea how long it waited for a final message that would never arrive

Space.com: Some of these missions seem as though they would have left a very short paper trail, and some of them have just barely become declassified. How did you go about finding all of these?

Pyle: This is true in many cases. While it's simple to buy a copy of something like [rocket pioneer] Wernher von Brauns "The Mars Project," getting more in-depth data on many of these programs was far more complicated. To add to the adventure, some have only been fully declassified in the past few years. For example, much of the material on the U.S. Air Force's Manned Orbiting Laboratory was posted in the National Reconnaissance Office's online archives in 2015. Other programs have been extensively studied in academic papers that are available. Still others exist only as documents from the era, or even as hearsay that must be vetted by sources familiar with the program and the time frame the Soviet-era stories were the toughest. But this is in part what made it such a compelling book project."

Space.com: You've been a spaceflight historian for quite a while, so I imagine you've been collecting these stories for some time. When and why did you decide to put them all in a book?

Pyle: I've been writing books about spaceflight since 2003. Prior to that, I was working in documentary television, and would steer projects towards space-related subjects whenever possible. This book originated as a pitch to a cable network for a show called "Secrets of Space" in the early 2000s. We got close a few times but were never able to begin production. The pitch languished for some time, and I decided about five years ago to recast it as a book, which would allow for a much deeper dive into the subject matter a huge plus. My agent made a deal with the good folks at Prometheus Books, and off we went.

Space.com: Of all the stories in your book that stood out to me, I think perhaps the most incredible was the idea in the late 1950s that the U.S. would have a military base on the moon and would actually be fighting moon wars against Russian moon armies within a decade. You even mention in the book that this may sound incredible, but that's just a testament to how intense the Cold War was. Were most people really convinced that spaceflight would advance at such a rapid clip? When do you think people started to realize that wouldn't be the case?

Pyle: Project Horizon was a 1959 U.S. Army study for a militarized moon base. It was pretty much [dead on arrival] when it was submitted, since things were moving in another direction by then NASA was a new civil space agency, and von Braun, who had worked on the Project Horizon study, had transferred there from the Army. When reading the Project Horizon proposal, I had to chuckle at some of the assumptions made the Redstone Arsenal [what is now ;NASA's Marshall Space Flight Center in Alabama] was just developing the Saturn I rocket and the flight rates and amount of cargo needed to build the Horizon base would have been staggering on the order of 150+ boosters, including spares.

All this would need to be transported to Christmas Island [also known as Kiritimati, part of the Republic of Kiribati] in the central Pacific, where the equatorially based launch site would be, and everything would have to go perfectly to be anywhere near their scheduled time of completion, about 1965 to 1966. The budgeted cost was about $6 billion in 1959 dollars. Later, as NASA began to look hard at their manned lunar mission options, especially direct ascent versus Earth orbit rendezvous, it began to sink in just how difficult this could all be. Of course, Project Horizon was a filing-cabinet item by then; it was, to my knowledge, not taken seriously after being submitted in 1959, and von Braun, as mentioned, had moved on.

Today, when you look at all 363 feet [111 meters] of a Saturn V moon rocket, and realize that only the last 13 feet [4 m] of it returned home from the moon, plans like Horizon feel like studies in technological hubris. But it would have been magnificent, had it worked, and one must admire the determination of the planners.

Space.com: On that same point, your book is a great illustration that some of the biggest leaps of spaceflight tech have come along because they had military motivations. Would you say it's true that the greatest spaceflight accomplishments of the 20th century were motivated by war and world dominance? Do you think that can change or is changing in the 21st century?

Pyle: Most of the unflown mission designs in the book were of military or quasi-military origins, with the one major exception being Project Orion, the atomic rocket. The late 1940s and early 1950s were a time of great paranoia and increasing fear. The United States had exited World War II as the sole power possessing nuclear weapons a comfortable position to be in at the time. Within a handful of years, thanks to clever physicists and good espionage, the Soviet Union had developed and tested both atomic and hydrogen bombs. At the time say, through the mid-1950s the only way to deliver such weapons was with lumbering, slow bomber aircraft. But what if some clever folks built rockets big enough to fling them across the globe at ballistic speeds, or placed them in an orbiting station that could drop them on U.S. targets at will? This was a huge concern.

So the plans for the Horizon lunar base, the Air Force's Lunex base, von Braun's inflatable "wheel" space station, the Dyna-Soar rocket plane and many others were based, at least in part, on this paranoia and the desire to seize the "high ground," however each branch of the military perceived that. And, of course, although Apollo was a civilian program, we know that it was born of geopolitics and the Kennedy administration's desire to find a pursuit in space in which we could assure a win over the Soviet Union something that would demonstrate the superiority of our technology, our political system and our people. A crewed lunar landing was the answer. This program, called Project Apollo, was almost curtailed many times, and it continues to astound me that it all worked, and within the decade.

I see great promise for a different outcome in the 21st century, a blending of international collaboration, commercial/government partnerships and private competition (mostly in the U.S. for the next decade) in space exploration and development.

Space.com: There are also some stories in your book about projections in the 1960s that humans would visit other planets by the 1980s. The fact that those estimates were wildly off target makes me feel nervous about NASA's current plans to get humans to Mars by the 2030s. Does learning about the history of humanity trying to get past the moon make you feel hopeful for future solar system exploration, or does it mostly inspire caution?

Pyle: What an interesting question! It was all so much simpler when von Braun penned "The Mars Project" in 1953 We thought that Mars might have a sufficiently dense atmosphere to support a gliding landing of his huge space-shuttle-like landing craft, that we could cross the gulf between Earth and Mars with a 10-ship armada of taxpayer-funded behemoths, and it would all proceed much like a submarine journey under the North Pole (which occurred in 1958).

But we soon learned that Mars was much more hostile than we had suspected, that Venus was a hell planet and that the moon, while far closer than either, was still a tremendous challenge. And as we continue to study the deep-space environment and microgravity, we find that we, the frail beings who evolved to live perfectly on the surface of our planet and nowhere else, are at great peril when journeying in space for extended periods. So, during the space race we learned much about spaceflight and the associated engineering and scientific issues involved, but this was the low-hanging fruit.

From here on out, the exploration of the solar system gets much harder. And a few hardy U.S.-based billionaires aside, our greatest enemy seems to be a lack of cohesive direction and the dogged determination to forge ahead, in my opinion. As [retired NASA Flight Director] Gene Kranz said to me at the end of an interview a few years back, as he fixed me with that steely eyed missile-man stare, "What America will dare, America can do." I think he's right, and for more than just America. Today, I might rephrase it as, "We know what we can do. What will we dare?"

Space.com: In Chapter 4, you talk about General Atomics, which was a commercial company that wanted to build a brand-new kind of rocket to get humans into space. Would you call this company a predecessor to companies like SpaceX? (While private companies have been involved in spaceflight since its inception, I'm asking if there's a similarity, because most of those companies contribute to existing human spaceflight missions rather than trying to initiate their own.)

Pyle: The idea of nuclear-pulse propulsion originated from Los Alamos [National Laboratory] in 1947 as a paper outlining an unmanned spacecraft. It was then restarted at General Atomics in 1958 on a slim budget, funded internally. It soon became clear that this was going to require more resources, and federal dollars became involved. It did begin in a fashion not entirely dissimilar from efforts such as SpaceX and Blue Origin, but without sexy billionaires at the helm it was a corporate decision.

Later that same year, the Advanced Research Projects Agency, or ARPA, (DARPA's predecessor) committed to spending a million dollars per year on the project, and soon, the Air Force took over funding, seeing military potential in the program. The studies continued with more engineers and physicists involved, and the plan was to launch a giant crewed spacecraft ranging from 10,000 to a million tons, from Nevada, using nuclear explosions. [Theoretical physicist and mathematician] Freeman Dyson calculated that only a few lives would be lost per launch from fallout, far less than a week of automotive accident deaths in the U.S. The idea was tested with small-scale models called "putt-putts" and appeared to work, but ultimately, the scale of the project and the politics of raw nuclear pollution resulting from the launches doomed it.

NASA did later look hard at launching a far smaller version of Orion on a Saturn V, which would initiate atomic explosions only after it had left the atmosphere. But by then, the Apollo program was front and center, and Project Orion was discontinued. I'll add that Dyson's motto was "Mars by 1965, Saturn by 1970" a spectacular notion. It could have changed the course of human space exploration!

Space.com: Your book takes a look back at 20th century spaceflight and highlights some of the really grand, inspiring visions that people had for missions and technologies. Those people weren't cranks, either; even if Project Orion or some of von Braun's grander visions never got off the ground, the community still did amazing things. So do you think people are still dreaming at the same scale that they were in the first few decades of spaceflight? Is there room to dream up things like Project Orion and military bases on the moon?

Pyle: Is there ever! And we are, thankfully, somewhat less focused on the military aspect, though defense projects are still quietly well-funded. When I heard Elon Musk's talk at Guadalajara last September, when he announced SpaceX's plans to go to Mars, I was thrilled. I had expected something along those general lines, but the sheer scale of it, and the raw will and determination behind it, gives me great hope. He may never pull it off at the scale he outlined (though I, for one, would never bet against him), but the mere fact that he is willing to put this grand, almost utopian vision out there, and use his own money to seed it, is wonderful.

Ditto Jeff Bezos and his colonization plans for space, along with smaller companies like Bigelow, Sierra Nevada and all the rest. And, of course, other countries' programs the European Space Agency's Moon Village, Chinas ambitious plans for human flights to the moon and Mars, and other national space efforts are inspiring. It will be a wonderful time in space exploration and development the forward-looking visions of the 20th century may come true, in some form, at last.

Follow Calla Cofield @callacofield. Follow us @Spacedotcom, Facebook and Google+. Original article on Space.com.

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Will Biotechnology Regulations Squelch Food and Farming Innovation? – Genetic Literacy Project

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Jon Entine, Executive Director, Genetic Literacy Project,oversaw the assignments and the editing of this series

INTRODUCTION:

Genetically engineered crops and animals (GMOs) have been a controversial public issue since the first products were introduced in the 1990s. They have posed unique challenges for governments to regulate. Although most working scientists in the field hold the opinion that genetic engineering, for the most part, is part of a continuum of the human manipulation of our food supply thats gone on for thousands of years, critics contend differently.

Many crop biotechnology skeptics frame their concerns in quasi-religious terms, as a violation of nature or fears that the increased use of GE foods will lead to a corporate takeover of our seed and food systems, and the adoption of an ecologically destructive industrialized agriculture system. GMOs have become a symbol of the battle over what our global, regional and local food systems should look like going forward.

The clout of the food movement that vocally rejects many aspects of conventional farming has exponentially increased since then, promoted by mainstream journalists, scientists and non-profit groups from Michael Pollan to Consumers Union to the Environmental Working Group. Organic leaders and lobbyists, such as Gary Hirshberg, founder of Stonyfield Organics and Just Label It, openly demonize conventional food and farming in defiance of their commitments agreed to in the 1990s that organic food would not be promoted at the expense of conventional agriculture. Attempts to reign in the unchecked influence of the conventional food critics have repeatedly failed; over much of the past decade, theyve had a sympathetic ear in Washington. Partly in response to the prevailing winds, the USDA has evolved increasingly byzantine regulatory structures when it comes to new GE products.

The Genetic Literacy Project 10-part series Beyond the Science II (Beyond the Science I can be viewed here) commences with this introductory article. Leading scientists, journalists and social scientists explore the ramifications of genetic engineering and so-called new breeding technologies (NBTs), specifically gene-editing technologies such as CRISPR. We will post two articles each week, on Tuesday and Wednesday, over the next 5 weeks.

Regulation is at the heart of this ongoing debate. Many scientists and entrepreneurs have come to view the two key agencies regulating GE in the United States the Food and Drug Administration and Department of Agriculture as places where innovation goes to die. Thats an exaggeration, but not without some truth; regulations are inherently political, and the winds have been blowing against technological breakthroughs in agriculture for much of the last decade. On average, it takes upwards of $125 million and 7-10 years for the Agriculture Department to approve a trait, exhausting almost half of a new products 20-year patent protection. No wonder the agricultural sector is consolidating, and most new products are innovated by larger corporations.

The regulatory climate may be changing, perhaps radically, in the United States and possibly in the United Kingdom, as the result of recent elections.

Many of the old rules and regulations regulating GE crops were set up in the 1980s and early 1990s. They are arguably creaky, overly-restrictive and do not account for dramatic increases in our understanding of how genetic engineering works and the now clear consensus on their safety.

Now with NBTs, which are largely unregulated since the techniques were not foreseen 30 years ago when regulations were first formulated, agricultural genetic research is at an inflection point: Will governments make the same mistake that they did previously and regulate innovation almost out of existence, or will they incorporate reasonable risk-risk and risk-benefit calculations in evaluating which technological advances should proceed with limited regulations?

Decisions on these issues will shape not only food and farming in Europe, North America and the industrialized nations, but the food insecure developing world, which looks to the West for regulatory guidance.

Gene Editing and Animals

The second article in our series, by University of California animal geneticist Alison Van Eenennaam, addresses the challenges of regulating genetically engineered animals. She focuses on dehorned cows, which have been developed without gene editing over many years with, at times, less than optimal results. Should gene editing be evaluated on a case-by-case basis triggered by the novelty of the traits, or should the entire process be heavily regulated the general approach favored by the European Union in regulating more conventional genetic engineering?

Pesticide Debate: How Should Agricultural Chemicals Be Regulated to Encourage Sustainability?

Dave Walton, an Iowa farmer, discusses the brouhaha that has erupted in recent years over the use of glyphosate, the active ingredient in the weed killer originally developed under patent by Monsanto. Many GMO critics are now expressing concerns over pesticide use in conventional agriculture, using glyphosate as a proxy for attacking the technology. Are their concerns appropriate? Walton, who grows both GE and non-GE crops and is director of the Iowa Soybean Association, has used glyphosate on his farm since the introduction of herbicide resistant crops in 1996. He uses on average a soda-sized cup of glyphosate per acre, and the use of the herbicide has allowed him to switch from more toxic chemicals. Most strikingly he discusses the sustainability impact if a glyphosate ban is imposed, as many activists are calling for.

Plant pathologist Steve Savage challenges us to think in a more nuanced way about a popular belief that organic farming is ecologically superior to conventional agriculture. The Agricultural Department has been a fractious mess in recent years in its efforts to oversee and encourage new breeding technologies. When the Clinton administration oversaw the founding of the National Organics Standards Board in 1995, USDA officials extracted the commitment from organic industry that the alternative farming system would not be promoted at the expense of conventional agriculture. After all, study after study, then and now, has established that organic farming offers no safety nor clear ecological benefits.

Let me be clear about one thing, said former Secretary of Agriculture Dan Glickman in December 2000. The organic label is not a statement about food safety, nor is organic a value judgment about nutrition or quality.

But thats not whats happened.

Regulations and the NGO Problem in Africa and Asia

While GE crops were pioneered in the United States and embraced in other western coun- tries outside of Europe, there has been resistance in regions of the world where these innovations could arguably bring the most impact: Africa and poorer sections of Asia. Ma- haletchumy Arujanan, executive director of Malaysian Biotechnology Information Centre and editor-in-chief of The Petri Dish, the first science newspaper in Malaysia, takes on the emerging Asian food security crisis posed by a parallel rise in population and living (and food consumption) standards. She reviews the successes and failures in various countries, and the effective campaigns by anti-GMO NGOs, mostly European funded, to block further biotech innovation.

Margaret Karembu, director of International Service for the Acquisition of Agribiotech Applications, Africa regional office (ISSSA) AfriCenter based in Nairobi, has found a similar pattern of mostly European-funded NGOs attempting to sabotage research and spread misinformation about the basic science of crop biotechnology. Africa is the ultimate organic experiment, and farmers have failed miserably using family agro-ecology techniques for decades. Cracks are beginning to form in the anti-GMO wall erected across the continent and there are hopes that young people will be attracted to farming, lured by the introduction of GE crops and other innovations.

Public Opinion and GMOs

Brandon McFadden, assistant professor in the Food and Resource Economics Department, University of Florida, addresses the complex views of consumers regarding innovation and GE foods. The public has a widely distorted perception of what genetic engineering entails, which helps explain why consumers remain so skeptical about technological innovation in farming.

Julie Kelly, a contributing writer to numerous publications including the Wall Street Journal, National Review and the GLP, takes on Hollywood in her analysis of the celebrity embrace of the anti-GMO movement. Who are the movers and shakers manipulating public opinion in favor of the organic movement and against conventional agriculture? Is the celebrity-backed science misinformation campaign working?

Future of GM Research and How the Public Debate May Evolve

Paul Vincelli, extension professor and Provosts Distinguished Service Professor at the University of Kentucky, has been perturbed about the attack on independent university researchers for working with the biotechnology industry over the years. By law, land grant university scientists are required to work with all stakeholders, particularly corporations who are developing the products used by farmers, including organic farmers. No, scientists who partner with corporations in research and product development are not shills. He rejects the knee jerk belief, advanced by many activist critics of GE crops, that corporate funding necessarily corruptsscience and should be banned.

Finally, risk expert David Ropeik has an optimistic take on the future. He believes 2016 may have been a turning point in the debate over GE foods. Technology rejectionists, from Greenpeace to labeling activists, are sounding increasingly shrill and less scientific. Gene editing, he believes, could undercut claims that GE foods are unsafe because they are unnatural. He is convinced, perhaps optimistically, that GE opponents will soon be viewed as science denialists.

We will see.

Anti-GMO critics cite opinion polls and the votes of anti-GMO legislators in Europe and elsewhere as proof that genetic engineering should be curtailed and more heavily regulated. Thats a rickety platform if one believes in science, however; science is not a popularity contest.

The Genetic Literacy Project is a 501(c)(3) non profit dedicated to helping the public, journalists, policy makers and scientists better communicate the advances and ethical and technological challenges ushered in by the biotechnology and genetics revolution, addressing both human genetics and food and farming. We are one of two websites overseen by the Science Literacy Project; our sister site, the Epigenetics Literacy Project, addresses the challenges surrounding emerging data-rich technologies.Jon Entineis the founder of the Science Literacy Project.

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Medical College of Wisconsin names new director for human genetics center – Milwaukee Business Journal

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Medical College of Wisconsin names new director for human genetics center
Milwaukee Business Journal
At the Mayo college in Rochester, Minn., Urrutia is a professor in the departments of biochemistry and molecular biology, biophysics and medicine. He is director of epigenomics education and academic relationships in the epigenomics program of the Mayo ...

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Studies point way to precision therapies for common class of genetic … – Medical Xpress

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February 7, 2017 by Adam Hadhazy Two Princeton University studies are opening important new windows into understanding an untreatable group of common genetic disorders known as RASopathies that affect approximately one child out of 1,000 and are characterized by distinct facial features, developmental delays, cognitive impairment and heart problems. The researchers observed in zebrafish and fruit fly embryos how cancer-related mutations in the RAS pathway a biochemical system cells use to transmit information from their exterior to their interior caused severe deformations. Fruit-fly embryos (above) showed how signals at the early stage of development (red in top photo) activate genes (purple in middle photo) and pattern structures in the fly larva (bottom photo.) . Credit: Stanislav Shvartsman, Department of Chemical and Biological Engineering

Two Princeton University studies are opening important new windows into understanding an untreatable group of common genetic disorders known as RASopathies that are characterized by distinct facial features, developmental delays, cognitive impairment and heart problems. The findings could help point the way toward personalized precision therapies for these conditions.

Although not widely known, RASopathies are among the most common genetic disorders, affecting approximately one child out of 1,000. RASopathies are caused by mutations within the RAS pathway, a biochemical system cells use to transmit information from their exterior to their interior.

"Human development is very complex and it's amazing that it goes right so often. However, there are certain cases where it does not, as with RASopathies," said Granton Jindal, co-lead author of the two studies. Both Jindal and the other co-lead author, Yogesh Goyal, are graduate students in the Department of Chemical and Biological Engineering and the Lewis-Sigler Institute for Integrative Genomics (LSI). Jindal and Goyal do their thesis research in the lab of Stanislav Shvartsman, professor of chemical and biological engineering and LSI.

"Our new studies are helping to explain the mechanisms underlying these disorders," Jindal said.

These studies were published this year, one in the Proceedings of the National Academy of Sciences (PNAS) and the other in Nature Genetics online. The researchers made the discoveries in zebrafish and fruit fliesanimals commonly used as simplified models of human genetics and Jindal and Goyal's specialties, respectively. Due to the evolutionary similarities in the RAS pathway across diverse species, changes in this pathway would also be similar. Thus, it is likely that significant parts of findings in animals would apply to humans as well, although further research is needed to confirm this.

The first paper published Jan. 3 in PNAS presented a way to rank the severity of different mutations involved in RASopathies. The researchers introduced 16 mutations one at a time in developing zebrafish embryos. As each organism developed, clear differences in the embryos' shapes became evident, revealing the strength of each mutation. The same mutant proteins produced similarly varying degrees of defects in fruit flies. Some of the mutations the researchers tested were already known to be involved in human cancers. The researchers noted that these cancer-related mutations caused more severe deformations in the embryos, aligning with the medical community's ongoing efforts to adapt anti-cancer compounds to treat RASopathies.

"Until now, there was no systematic way of comparing different mutation severities for RASopathies effectively," Goyal said.

Jindal added, "This study is an important step for personalized medicine in determining a diagnosis to a first approximation." The study therefore suggested a path forward to human diagnostic advances, potentially enabling health care professionals to offer better diagnoses and inform caretakers about patients' disease progression.

The study went further and examined the use of an experimental cancer-fighting drug being investigated as a possible way to treat RASopathies. The researchers demonstrated that the amount of medication necessary to correct the developmental defects in the zebrafish embryos corresponded with the mutation's severitymore severe mutations required higher dosages.

The more recent paper, published online by Nature Genetics Feb. 6, reports an unexpected twist in treatment approach to some RASopathies. Like all cellular pathways, the RAS pathway is a series of molecular interactions that changes a cell's condition. Conventional wisdom has held that RASopathies are triggered by overactive RAS pathways, which a biologist would call excessive signaling.

The Nature Genetics study, however, found that some RASopathies could result from insufficient signaling along the RAS pathway in certain regions of the body. This means that drugs intended to treat RASopathies by tamping down RAS pathway signaling might actually make certain defects worse.

"To our knowledge, our study is the first to find lower signaling levels that correspond to a RASopathy disease," Goyal said. "Drugs under development are primarily RAS-pathway inhibitors aimed at reducing the higher activity, so maybe we need to design drugs that only target specific affected tissues, or investigate alternative, novel treatment options."

The Nature Genetics study also found that RAS pathway mutations cause defects by changing the timing and specific locations of embryonic development. For example, in normal fruit fly cells, the RAS pathway only turns on when certain natural cues are received from outside the cell. In the mutant cells, however, the RAS pathway in certain parts of fly embryo abnormally activated before these cues were received. This early activation disturbed the delicate process of embryonic development. The researchers found similar behavior in zebrafish cells.

"Our integrative approach has allowed us to make enormous progress in understanding RASopathies, some of which have just been identified in the last couple of decades," Shvartsman said. "With continued steps forward in both basic and applied science, as we've shown with our new publications, we hope to develop new ideas for understanding and treatment of a large class of developmental defects."

Princeton co-authors of the two papers include Trudi Schpbach, the Henry Fairfield Osborn Professor of Biology and professor of molecular biology, and Rebecca Burdine, an associate professor of molecular biology, as well as co-advisers to Goyal and Jindal; Alan Futran, a former graduate student in the Department of Chemical and Biological Engineering and LSI; graduate student Eyan Yeung of the Department of Molecular Biology and LSI; Jos Pelliccia, a graduate student in the Department of Molecular Biology; seniors in molecular biology Iason Kountouridis and Kei Yamaya; and Courtney Balgobin Class of 2015.

Bruce Gelb, a pediatric cardiologist specializing in cardiovascular genetics and the director of the Mindich Child Health and Development Institute at the Mount Sinai School of Medicine in New York, described the two new studies as "wonderful" in advancing the understanding of altered biology in RASopathies and developing a framework for comparing mutation strengths, bringing effective treatments significantly closer.

"At this time, most of the issues that arise from the RASopathies are either addressed symptomatically or cannot be addressed," Gelb said. "The work [these researchers] are undertaking could lead to true therapies for the underlying problem."

Explore further: New insight into RASopathy-associated lymphatic defects

More information: Granton A. Jindal et al. In vivo severity ranking of Ras pathway mutations associated with developmental disorders, Proceedings of the National Academy of Sciences (2017). DOI: 10.1073/pnas.1615651114

Yogesh Goyal et al. Divergent effects of intrinsically active MEK variants on developmental Ras signaling, Nature Genetics (2017). DOI: 10.1038/ng.3780

The RAS pathway is a cellular signaling pathway that regulates growth and development in humans. RASopathies are a group of diseases characterized by defects in RAS signaling.

Researchers have successfully targeted an important molecular pathway that fuels a variety of cancers and related developmental syndromes called "Rasopathies."

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Different genetic mistakes driving skin cancer may affect how patients respond to the drug vemurafenib, providing grounds to screen people with melanoma skin cancer before treatment, a new study by Cancer Research UK scientists ...

May 5, 2016A cell-to-cell signaling network that serves as a developmental timer could provide a framework for better understanding the mechanisms underlying human heart valve disease, say University of Oregon scientists.

It's been more than 10 years since Japanese researchers Shinya Yamanaka, M.D., Ph.D., and his graduate student Kazutoshi Takahashi, Ph.D., developed the breakthrough technique to return any adult cell to its earliest stage ...

Two Princeton University studies are opening important new windows into understanding an untreatable group of common genetic disorders known as RASopathies that are characterized by distinct facial features, developmental ...

The world's biggest study into an individual's genetic make-up and the risk of developing lung disease could allow scientists to more accurately 'predict' - based on genes and smoking - your chance of developing COPD, a deadly ...

A poor diet during pregnancy can cause biological changes that last throughout life, according to research from Imperial College London.

UT Southwestern Medical Center researchers have identified a gene that protects the gut from inflammatory bowel disease (IBD).

In the largest, deepest search to date, the international Genetic Investigation of Anthropometric Traits (GIANT) Consortium has uncovered 83 new DNA changes that affect human height. These changes are uncommon or rare, but ...

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Police turn to DNA phenotyping as experts attempt to put a face on crime – The Denver Channel

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Winter Storm Watchissued February 5 at 3:02PM MST expiring February 8 at 6:00PM MST in effect for: Grand, Jackson

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Winter Storm Watchissued February 5 at 12:17AM MST expiring February 8 at 12:00PM MST in effect for: Archuleta, Delta, Dolores, Eagle, Garfield, Gunnison, Hinsdale, La Plata, Mesa, Moffat, Montezuma, Montrose, Ouray, Pitkin, Rio Blanco, Routt, San Juan, San Miguel

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