Monthly Archives: August 2016

NATO – Council on Foreign Relations

Posted: August 25, 2016 at 4:21 pm

Op-Ed What Trump Doesnt Know About Allies Author: Stephen Sestanovich July 30, 2016 New York Times

Donald Trump's suggestion that NATO allies would lose U.S. protection unless they "pay" more for their defense is a reminder of how easily presidents can blunder their way into trouble, writes CFR's Stephen Sestanovich.

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Inthe last year, some39,000 migrants, mostly from North Africa, tried to make their way to the United Kingdom from the French port of Calais by boarding trucks and trains crossing the English Channel.

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A close call. It is tempting to view the chaos in Libya today as yet one more demonstration of the futility of U.S.-led military interventions. That is precisely the case that Alan Kuperman makes in his article (Obamas Libya Debacle, March/April 2015), which asserts that NATOs 2011 intervention in Libya was an abject failure that set free Libyas vast conventional weapons stockpiles, gave rise to extremist groups, and even exacerbated the conflict in Syria.

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Janine Davidson presents an interactive model of NATO members' military spending from 1949 to the present day. This visualization also tracks the total proportion of U.S. contribution over time.

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This document was issued on September 5, 2014, after a summit with NATO leaders which addressed the instability in Europe between Russia and the Ukraine and the threat of the Islamic State of Iraq and the Levant (ISIL). The declaration includes increased sanctions against Russia and a rapid-reaction force based in Eastern Europe to act against moves from the Russian military.

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John Mearsheimer, R. Wendell Harrison distinguished service professor of political science at the University of Chicago and author of "Why the Ukraine Crisis is the West's Fault" in the September/October 2014 issue of Foreign Affairs, on the unintended effects of NATO expansion.

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Listen to Ivo Daalder, former U.S. permanent representative to NATO and president of the Chicago Council on Global Affairs and Michael McFaul, former U.S. ambassador to Russia and professor of political science at Stanford University discuss NATO's role in addressing global challenges, including Afghanistan, Ukraine, and ISIS.

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Adam Mount and Hans Kristensen argue that tactical nuclear bombs in Europe are no longer useful for defense, deterrance, or assurance. They have had little effect on Russian President Vladimir Putin's transgressions in Eastern Europe and instead detract from more useful defense initiatives.

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Janine Davidson and Emerson Brooking argue that, on the eve of the 2014 NATO Wales Summit, the ongoing war in Afghanistan should not be relegated to a "side issue" in light of the crisis in Ukraine and growing threat of ISIS. The next few months will be critical in determining that Afghanistan does not follow the path of Iraq.

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When Western leaders gather for the NATO summit in Wales next week, they will be expected to answer calls to revive the old alliance in order to confront Russias gradual invasion of Ukraine. Despite this new clarity of purpose, however, the alliance remains profoundlydivided.

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With crises brewing in Ukraine and the Middle East, the transatlantic alliance must develop new capabilities to address the rising threat of unconventional warfare, says CFR's Janine Davidson.

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U.S. President Barack Obama and Polish President Bronisaw Komorowski held a press conference on June 3, 2014, to discuss commitments to NATO and Ukraine.

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Secretary of Defense Chuck Hagel spoke at the Woodrow Wilson International Center Forum on May 2, 2014. He discussed strengthening NATO, in the context of Russia's annexation of Crimea and U.S. defense budget constraints.

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Russian aggression in Ukraine has breathed new life into the Cold War-era security alliance, prompting allies to reinforce defenses in Eastern Europe and expand cooperation with nonmembers.

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The Foreign Policy Initiative organized fifty-two former U.S. government officials and foreign policy experts to sign a bipartisan letter to President Obama regarding policy to respond to Russia's actions in Ukraine.

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NATO's response to Russia's annexation of Crimea may require it to bolster eastern European members with both military and non-military actions, says expert Christopher S. Chivvis.

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NATO Secretary-General Anders Fogh Rasmussen spoke at a Brookings Institution event, The Future of the Alliance: Revitalizing NATO for a Changing World. Secretary-General Rasmussen's remarks, as prepared for delivery, are titled "Why NATO Matters to America."

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"Europe is under pressure, both internally and from its allies, to take more responsibility for defence and security, especially in its immediate neighbourhood. The post-Cold War history of European deployments in Europe and joint NATO missions provide abundant evidence of such demands. Currently, US defence spending represents 72 percent of the NATO total up from 63 percent in 2001."

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Although there is no formal institutional connection between India and NATO, India and the NATO allies, most importantly the United States, informally share an interest in maintaining maritime security in the Indian Ocean and have spent significant resources to combat piracy in this vast area.

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U.S. missile defense in the twenty-first century is focused on emerging threats from North Korea and Iran, but critics say these systems are too costly and largely unproven.

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NATO - Council on Foreign Relations

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First Amendment – Watchdog.org

Posted: at 4:20 pm

By M.D. Kittle / August 14, 2016 / First Amendment, Free Speech, News, Power Abuse, Wisconsin / No Comments

There is a vital need for citizens to have an effective remedy against government officials who investigate them principally because of their partisan affiliation and political speech.

By M.D. Kittle / August 8, 2016 / Commentary, First Amendment, Free Speech, National, Wisconsin / No Comments

Thats precisely what I expected from a party whose platform includes rewriting the First Amendment

By M.D. Kittle / August 3, 2016 / First Amendment, Free Speech, News, Power Abuse, Wisconsin / No Comments

The question that arises is do conservatives have civil rights before Judge Lynn Adelman?

By M.D. Kittle / August 2, 2016 / First Amendment, News, Power Abuse, Wisconsin / No Comments

Now, years after defendants unlawfully seized and catalogued millions of our sensitive documents, we ask the court to vindicate our rights under federal law.

By M.D. Kittle / July 25, 2016 / First Amendment, National, News, Politics & Elections, Wisconsin / No Comments

Moore has uttered some of the more inflammatory, ill-informed statements in Congress.

By M.D. Kittle / July 14, 2016 / First Amendment, Judiciary, News, Power Abuse, Wisconsin / No Comments

The process continues to be the punishment for people who were found wholly innocent of any wrongdoing, she said.

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Human mitochondrial genetics – Wikipedia, the free …

Posted: at 4:19 pm

Human mitochondrial genetics is the study of the genetics of human mitochondrial DNA (the DNA contained in human mitochondria). The human mitochondrial genome is the entirety of hereditary information contained in human mitochondria. Mitochondria are small structures in cells that generate energy for the cell to use, and are hence referred to as the "powerhouses" of the cell.

Mitochondrial DNA (mtDNA) is not transmitted through nuclear DNA (nDNA). In humans, as in most multicellular organisms, mitochondrial DNA is inherited only from the mother's ovum. There are theories, however, that paternal mtDNA transmission in humans can occur under certain circumstances.[1]

Mitochondrial inheritance is therefore non-Mendelian, as Mendelian inheritance presumes that half the genetic material of a fertilized egg (zygote) derives from each parent.

Eighty percent of mitochondrial DNA codes for mitochondrial RNA, and therefore most mitochondrial DNA mutations lead to functional problems, which may be manifested as muscle disorders (myopathies).

Because they provide 30 molecules of ATP per glucose molecule in contrast to the 2 ATP molecules produced by glycolysis, mitochondria are essential to all higher organisms for sustaining life. The mitochondrial diseases are genetic disorders carried in mitochondrial DNA, or nuclear DNA coding for mitochondrial components. Slight problems with any one of the numerous enzymes used by the mitochondria can be devastating to the cell, and in turn, to the organism.

In humans, mitochondrial DNA (mtDNA) forms closed circular molecules that contain 16,569,[2][3] DNA base pairs,[4] with each such molecule normally containing a full set of the mitochondrial genes. Each human mitochondrion contains, on average, approximately 5 such mtDNA molecules, with the quantity ranging between 1 and 15.[4] Each human cell contains approximately 100 mitochondria, giving a total number of mtDNA molecules per human cell of approximately 500.[4]

Because mitochondrial diseases (diseases due to malfunction of mitochondria) can be inherited both maternally and through chromosomal inheritance, the way in which they are passed on from generation to generation can vary greatly depending on the disease. Mitochondrial genetic mutations that occur in the nuclear DNA can occur in any of the chromosomes (depending on the species). Mutations inherited through the chromosomes can be autosomal dominant or recessive and can also be sex-linked dominant or recessive. Chromosomal inheritance follows normal Mendelian laws, despite the fact that the phenotype of the disease may be masked.

Because of the complex ways in which mitochondrial and nuclear DNA "communicate" and interact, even seemingly simple inheritance is hard to diagnose. A mutation in chromosomal DNA may change a protein that regulates (increases or decreases) the production of another certain protein in the mitochondria or the cytoplasm; this may lead to slight, if any, noticeable symptoms. On the other hand, some devastating mtDNA mutations are easy to diagnose because of their widespread damage to muscular, neural, and/or hepatic tissues (among other high-energy and metabolism-dependent tissues) and because they are present in the mother and all the offspring.

Mitochondrial genome mutations are passed on 100% of the time from mother to all her offspring. So, if a female has a mitochondrial trait, all offspring inherit it. However, if a male has a mitochondrial trait, no offspring inherit it. The number of affected mtDNA molecules inherited by a specific offspring can vary greatly because

It is possible, even in twin births, for one baby to receive more than half mutant mtDNA molecules while the other twin may receive only a tiny fraction of mutant mtDNA molecules with respect to wildtype (depending on how the twins divide from each other and how many mutant mitochondria happen to be on each side of the division). In a few cases, some mitochondria or a mitochondrion from the sperm cell enters the oocyte but paternal mitochondria are actively decomposed.

Genes in the human mitochondrial genome are as follows.

It was originally incorrectly believed that the mitochondrial genome contained only 13 protein-coding genes, all of them encoding proteins of the electron transport chain. However, in 2001, a 14th biologically active protein called humanin was discovered, and was found to be encoded by the mitochondrial gene MT-RNR2 which also encodes part of the mitochondrial ribosome (made out of RNA):

Unlike the other proteins, humanin does not remain in the mitochondria, and interacts with the rest of the cell and cellular receptors. Humanin can protect brain cells by inhibiting apoptosis. Despite its name, versions of humanin also exist in other animals, such as rattin in rats.

Mitochondrial rRNA is encoded by MT-RNR1 (12S) and MT-RNR2 (16S).

The following genes encode tRNA:

In humans, the light strand of mtDNA carries 28 genes and the heavy strand of mtDNA carries only 9 genes.[5] Eight of the 9 genes on the heavy strand code for mitochondrial tRNA molecules. Human mtDNA consists of 16,569 nucleotide pairs. The entire molecule is regulated by only one regulatory region which contains the origins of replication of both heavy and light strands. The entire human mitochondrial DNA molecule has been mapped[1][2].

The genetic code is, for the most part, universal, with few exceptions: mitochondrial genetics includes some of these. For most organisms the "stop codons" are "UAA", "UAG", and "UGA". In vertebrate mitochondria "AGA" and "AGG" are also stop codons, but not "UGA", which codes for tryptophan instead. "AUA" codes for isoleucine in most organisms but for methionine in vertebrate mitochondrial mRNA.

There are many other variations among the codes used by other mitochondrial m/tRNA, which happened not to be harmful to their organisms, and which can be used as a tool (along with other mutations among the mtDNA/RNA of different species) to determine relative proximity of common ancestry of related species. (The more related two species are, the more mtDNA/RNA mutations will be the same in their mitochondrial genome).

Using these techniques, it is estimated that the first mitochondria arose around 1.5 billion years ago. A generally accepted hypothesis is that mitochondria originated as an aerobic prokaryote in a symbiotic relationship within an anaerobic eukaryote.

Mitochondrial replication is controlled by nuclear genes and is specifically suited to make as many mitochondria as that particular cell needs at the time.

Mitochondrial transcription in Human is initiated from three promoters, H1, H2, and L (heavy strand 1, heavy strand 2, and light strand promoters). The H2 promoter transcribes almost the entire heavy strand and the L promoter transcribes the entire light strand. The H1 promoter causes the transcription of the two mitochondrial rRNA molecules.[6]

When transcription takes place on the heavy strand a polycistronic transcript is created. The light strand produces either small transcripts, which can be used as primers, or one long transcript. The production of primers occurs by processing of light strand transcripts with the Mitochondrial RNase MRP (Mitochondrial RNA Processing). The requirement of transcription to produce primers links the process of transcription to mtDNA replication. Full length transcripts are cut into functional tRNA, rRNA, and mRNA molecules.[citation needed]

The process of transcription initiation in mitochondria involves three types of proteins: the mitochondrial RNA polymerase (POLRMT), mitochondrial transcription factor A (TFAM), and mitochondrial transcription factors B1 and B2 (TFB1M, TFB2M). POLRMT, TFAM, and TFB1M or TFB2M assemble at the mitochondrial promoters and begin transcription. The actual molecular events that are involved in initiation are unknown, but these factors make up the basal transcription machinery and have been shown to function in vitro.[citation needed]

Mitochondrial translation is still not very well understood. In vitro translations have still not been successful, probably due to the difficulty of isolating sufficient mt mRNA, functional mt rRNA, and possibly because of the complicated changes that the mRNA undergoes before it is translated.[citation needed]

The Mitochondrial DNA Polymerase (Pol gamma, encoded by the POLG gene) is used in the copying of mtDNA during replication. Because the two (heavy and light) strands on the circular mtDNA molecule have different origins of replication, it replicates in a D-loop mode. One strand begins to replicate first, displacing the other strand. This continues until replication reaches the origin of replication on the other strand, at which point the other strand begins replicating in the opposite direction. This results in two new mtDNA molecules. Each mitochondrion has several copies of the mtDNA molecule and the number of mtDNA molecules is a limiting factor in mitochondrial fission. After the mitochondrion has enough mtDNA, membrane area, and membrane proteins, it can undergo fission (very similar to that which bacteria use) to become two mitochondria. Evidence suggests that mitochondria can also undergo fusion and exchange (in a form of crossover) genetic material among each other. Mitochondria sometimes form large matrices in which fusion, fission, and protein exchanges are constantly occurring. mtDNA shared among mitochondria (despite the fact that they can undergo fusion).[citation needed]

Mitochondrial DNA is susceptible to damage from free oxygen radicals from mistakes that occur during the production of ATP through the electron transport chain. These mistakes can be caused by genetic disorders, cancer, and temperature variations. These radicals can damage mtDNA molecules or change them, making it hard for mitochondrial polymerase to replicate them. Both cases can lead to deletions, rearrangements, and other mutations. Recent evidence has suggested that mitochondria have enzymes that proofread mtDNA and fix mutations that may occur due to free radicals. It is believed that a DNA recombinase found in mammalian cells is also involved in a repairing recombination process. Deletions and mutations due to free radicals have been associated with the aging process. It is believed that radicals cause mutations which lead to mutant proteins, which in turn led to more radicals. This process takes many years and is associated with some aging processes involved in oxygen-dependent tissues such as brain, heart, muscle, and kidney. Auto-enhancing processes such as these are possible causes of degenerative diseases including Parkinson's, Alzheimer's, and coronary artery disease.[citation needed]

Because mitochondrial growth and fission are mediated by the nuclear DNA, mutations in nuclear DNA can have a wide array of effects on mtDNA replication. Despite the fact that the loci for some of these mutations have been found on human chromosomes, specific genes and proteins involved have not yet been isolated. Mitochondria need a certain protein to undergo fission. If this protein (generated by the nucleus) is not present, the mitochondria grow but they do not divide. This leads to giant, inefficient mitochondria. Mistakes in chromosomal genes or their products can also affect mitochondrial replication more directly by inhibiting mitochondrial polymerase and can even cause mutations in the mtDNA directly and indirectly. Indirect mutations are most often caused by radicals created by defective proteins made from nuclear DNA.[citation needed]

In total, the mitochondrion hosts about 3000 different types of proteins, but only about 13 of them are coded on the mitochondrial DNA. Most of the 3000 types of proteins are involved in a variety of processes other than ATP production, such as porphyrin synthesis. Only about 3% of them code for ATP production proteins. This means most of the genetic information coding for the protein makeup of mitochondria is in chromosomal DNA and is involved in processes other than ATP synthesis. This increases the chances that a mutation that will affect a mitochondrion will occur in chromosomal DNA, which is inherited in a Mendelian pattern. Another result is that a chromosomal mutation will affect a specific tissue due to its specific needs, whether those may be high energy requirements or a need for the catabolism or anabolism of a specific neurotransmitter or nucleic acid. Because several copies of the mitochondrial genome are carried by each mitochondrion (2-10 in humans), mitochondrial mutations can be inherited maternally by mtDNA mutations which are present in mitochondria inside the oocyte before fertilization, or (as stated above) through mutations in the chromosomes.[citation needed]

Mitochondrial diseases range in severity from asymptomatic to fatal, and are most commonly due to inherited rather than acquired mutations of mitochondrial DNA. A given mitochondrial mutation can cause various diseases depending on the severity of the problem in the mitochondria and the tissue the affected mitochondria are in. Conversely, several different mutations may present themselves as the same disease. This almost patient-specific characterization of mitochondrial diseases (see Personalized medicine) makes them very hard to accurately recognize, diagnose and trace. Some diseases are observable at or even before birth (many causing death) while others do not show themselves until late adulthood (late-onset disorders). This is because the number of mutant versus wildtype mitochondria varies between cells and tissues, and is continuously changing. Because cells have multiple mitochondria, different mitochondria in the same cell can have different variations of the mtDNA. This condition is referred to as heteroplasmy. When a certain tissue reaches a certain ratio of mutant versus wildtype mitochondria, a disease will present itself. The ratio varies from person to person and tissue to tissue (depending on its specific energy, oxygen, and metabolism requirements, and the effects of the specific mutation). Mitochondrial diseases are very numerous and different. Apart from diseases caused by abnormalities in mitochondrial DNA, many diseases are suspected to be associated in part by mitochondrial dysfunctions, such as diabetes mellitus, forms of cancer and cardiovascular disease, lactic acidosis, specific forms of myopathy, osteoporosis, Alzheimer's disease, Parkinsons's disease, stroke, male infertility and which are also believed to play a role in the aging process.[citation needed]

Human mtDNA can also be used to help identify individuals.[7] Forensic laboratories occasionally use mtDNA comparison to identify human remains, and especially to identify older unidentified skeletal remains. Although unlike nuclear DNA, mtDNA is not specific to one individual, it can be used in combination with other evidence (anthropological evidence, circumstantial evidence, and the like) to establish identification. mtDNA is also used to exclude possible matches between missing persons and unidentified remains.[8] Many researchers believe that mtDNA is better suited to identification of older skeletal remains than nuclear DNA because the greater number of copies of mtDNA per cell increases the chance of obtaining a useful sample, and because a match with a living relative is possible even if numerous maternal generations separate the two. American outlaw Jesse James's remains were identified using a comparison between mtDNA extracted from his remains and the mtDNA of the son of the female-line great-granddaughter of his sister.[9] Similarly, the remains of Alexandra Feodorovna (Alix of Hesse), last Empress of Russia, and her children were identified by comparison of their mitochondrial DNA with that of Prince Philip, Duke of Edinburgh, whose maternal grandmother was Alexandra's sister Victoria of Hesse.[10] Similarly to identify Emperor Nicholas II remains his mitochondrial DNA was compared with that of James Carnegie, 3rd Duke of Fife, whose maternal great-grandmother Alexandra of Denmark (Queen Alexandra) was sister of Nicholas II mother Dagmar of Denmark (Empress Maria Feodorovna).[11]

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5th International Conference and Exhibition on Cell and …

Posted: at 4:18 pm

Track-1 Cell Therapy:

Cell therapyas performed by alternativemedicinepractitioners is very different from the controlled research done by conventionalstem cellmedical researchers. Alternative practitioners refer to their form of cell therapy by several other different names includingxenotransplanttherapy,glandular therapy, and fresh cell therapy. Proponents ofcell therapyclaim that it has been used successfully to rebuild damaged cartilage in joints, repair spinal cord injuries,strengthen a weakenedimmune system, treat autoimmune diseases such as AIDS, and help patients withneurological disorderssuch as Alzheimers disease,Parkinson's diseaseand epilepsy.

Related Conferences:

6th International Conference onTissue Engineering & Regenerative Medicine, Baltimore, USA, Aug 20-22, 2017; 8th World Congress and Expo onCell & Stem Cell Research,Orlando, USA, March 20-22, 2017; 15thWorld Congress on Biotechnology and Biotech Industries Meet,Rome, Italy,March 20-21,2017; 2nd International Conference onGenetic Counselling and Genomic Medicine ,Beijing, China,July 10-12, 2017; International Conference onClinical and Molecular Genetics, Las Vegas, USA, April 24-26, 2017.

Track-2 Gene therapy:

Gene therapyand cell therapy are overlapping fields of biomedical research with the goals of repairing the direct cause of genetic diseases in the DNA orcellularpopulation, respectively. The development of suitablegene therapytreatments for manygenetic diseasesand some acquired diseases has encountered many challenges and uncovered new insights into gene interactions and regulation. Further development often involves uncovering basic scientific knowledge of the affected tissues, cells, and genes, as well as redesigning vectors, formulations, and regulatory cassettes for the genes.Cell therapyis expanding its repertoire of cell types for administration.Cell therapytreatment strategies include isolation and transfer of specific stem cell populations, administration of effector cells, and induction of mature cells to becomepluripotent cells, and reprogramming of mature cells.

Related Conferences:

2nd International Conference onMolecular Biology , London, UK ,June 22-24, 2017; 3rd World Bio Summit & Expo, Abu Dhabi, UAE, June 19-21, 2017; 5th International Conference onIntegrative Biology, London, UK, June 19-21, 2017; 2nd World Congress on Human Genetics, Chicago, USA, July 24-26, 2017; 9th International Conference onGenomics and Pharmacogenomics, Chicago, USA, July 13-14, 2017.

Track-3 Cell and gene therapy products:

Articles containing or consisting ofhuman cellsor tissues that are intended for implantation,transplantation, infusion, or transfer to a human recipient.Gene therapiesare novel and complex products that can offer unique challenges in product development. Hence, ongoing communication between the FDA and stakeholders is essential to meet these challenges.Gene therapy productsare being developed around the world, the FDA is engaged in a number of international harmonization activities in this area.

Examples:Musculoskeletal tissue, skin, ocular tissue, human heart valves;vascular graft, dura mater, reproductive tissue/cells, Stem/progenitor cells,somatic cells, Cells transduced withgene therapyvectors , Combination products (e.g., cells or tissue + device)

Related Conferences:

7th International Conference onPlant Genomics, Bangkok, Thailand, July 03-05, 2017; 15th Euro Biotechnology Congress, Valencia, Spain, June 05-07, 2017; International Conference onIntegrative Medicine & Nutrition, Dubai, UAE, May11-13, 2017; 14th Asia-Pacific Biotech Congress, April 10-12, 2017; Beijing, China,15th Biotechnology Congress, Baltimore, USA, June 22-23, 2017.

Track-4 Cellular therapy:

Cellular therapy, also calledlive cell therapy, cellular suspensions, glandular therapy, fresh cell therapy, sick cell therapy,embryonic cell therapy, andorgan therapy- refers to various procedures in which processed tissue from animal embryos, foetuses or organs, is injected or taken orally. Products are obtained from specific organs or tissues said to correspond with the unhealthy organs or tissues of the recipient. Proponents claim that the recipient's body automatically transports the injected cells to thetarget organs, where they supposedly strengthen them and regenerate their structure. The organs and glands used in cell treatment include brain, pituitary,thyroid, adrenals, thymus, liver,kidney, pancreas, spleen, heart,ovary, testis, and parotid. Several different types of cell or cell extract can be given simultaneously - some practitioners routinely give up to 20 or more at once.

Related Conferences:

3rd International Conference onSynthetic Biology, Munich, Germany, July 20-21, 2017; 5th International Conference and Exhibition onCell and Gene Therapy,Madrid, Spain,Mar 2-3, 2017;International Conference onCell Signalling and Cancer Therapy,Paris, France,Aug 20-22, 2017; 7th Annual Conference on Stem Cell and Regenerative Medicine, Paris, France,Aug 04-05, 2016;3rd International Conference & Exhibition onTissue Preservation and Bio banking, Baltimore, USA,June 29-30, 2017.

Track-5 Cancer gene therapy:

Cancer therapiesare drugs or other substances that block the growth and spread ofcancerby interfering with specific molecules ("molecular targets") that are involved in the growth, progression, and spread ofcancer. Many cancer therapies have been approved by the Food and Drug Administration (FDA) to treat specific types of cancer. The development of targetedtherapiesrequires the identification of good targets that is, targets that play a key role in cancer cell growth and survival. One approach to identify potential targets is to compare the amounts of individualproteinsin cancer cells with those in normal cells.Proteinsthat are present in cancer cells but not normal cells or that are more abundant incancercells would be potential targets, especially if they are known to be involved incell growthor survival.

Related Conferences:

2nd Biotechnology World Convention,London, UK,May 25-27, 2017; International Conference on Animal and Human Cell Culture, Jackson Ville, USA, Sep 25-27, 2017; 9th International Conference onCancer Genomics, Chicago, USA, May 29-31, 2017; 6th International Conference onTissue Engineering & Regenerative Medicine, Baltimore, USA, Aug 20-22, 2017; 8th World Congress and Expo onCell & Stem Cell Research, Orlando, USA, March 20-22, 2017.

Track-6 Nano therapy:

Nano Therapymay be defined as the monitoring, repair, construction and control of human biological systems at themolecular level, using engineerednanodevicesand nanostructures. Basic nanostructured materials, engineeredenzymes, and the many products of biotechnology will be enormously useful in near-term medical applications. However, the full promise ofnanomedicineis unlikely to arrive until after the development of precisely controlled or programmable medical Nano machines andnanorobots.

Related Conferences:

15thWorld Congress on Biotechnology and Biotech Industries Meet ,Rome, Italy,March 20-21, 2017 ;2nd International Conference onGenetic Counselling and Genomic Medicine ,Beijing, China,July 10-12, 2017; International Conference onClinical and Molecular Genetics, Las Vegas, USA, April 24-26, 2017; 15th Euro Biotechnology Congress, Valencia, Spain, June 05-07, 2017; International Conference onIntegrative Medicine & Nutrition, Dubai, UAE, May11-13, 2017.

Track-7 Skin cell therapy:

Stem cellshave newly become a huge catchphrase in theskincarebiosphere. Skincare specialists are not usingembryonic stem cells; it is impossible to integrate live materials into a skincare product. Instead, scientists are creating products with specialized peptides andenzymesor plantstem cellswhich, when applied topically on the surface, help to protect the human skinstem cellsfrom damage and deterioration or stimulate the skins own stem cells. Currently, the technique is mainly used to save the lives of patients who have third degree burns over very large areas of their bodies.

Related Conferences:

5th International Conference and Exhibition onCell and Gene Therapy,Madrid,Spain,Mar 2-3, 2017;International Conference onCell Signalling and Cancer Therapy,Paris, France,Aug 20-22, 2017;2nd Biotechnology World Convention,London, UK,May 25-27, 2017; International Conference on Animal and Human Cell Culture, Jackson Ville, USA, Sep 25-27, 2017; 9th International Conference onCancer Genomics, Chicago, USA, May 29-31, 2017.

Track-8 HIV gene therapy:

Highly activeantiretroviral therapydramatically improves survival inHIV-infected patients. However, persistence of HIV in reservoirs has necessitated lifelong treatment that can be complicated bycumulative toxicities, incomplete immune restoration, and the emergence of drug-resistant escapemutants. Cell and gene therapies offer the promise of preventing progressiveHIV infectionby interfering with HIV replication in the absence of chronicantiviral therapy.

Related Conferences:

3rd International Conference onSynthetic Biology, Munich, Germany, July 20-21, 2017; International Conference onIntegrative Medicine & Nutrition, Dubai, UAE, May11-13, 2017; International Conference on Animal and Human Cell Culture, Jackson Ville, USA, Sep 25-27, 2017; International Conference onCell Signalling and Cancer Therapy,Paris, France,Aug 20-22, 2017;7th Annual Conference on Stem Cell and Regenerative Medicine,Paris,France,Aug 04-05, 2016.

Track-9 Diabetes for gene therapy:

Cell therapyapproaches for this disease are focused on developing the most efficient methods for the isolation ofpancreasbeta cells or appropriatestem cells, appropriate location forcell transplant, and improvement of their survival upon infusion. Alternatively, gene andcell therapyscientists are developing methods to reprogram some of the other cells of the pancreas to secreteinsulin. Currently ongoingclinical trialsusing these gene andcell therapystrategies hold promise for improved treatments of type I diabetes in the future. The firstgene therapyapproach to diabetes was put forward shortly after the cloning of theinsulingene. It was proposed that non-insulin producing cells could be made into insulin-producingcells using a suitable promoter and insulin gene construct, and that these substitute cells could restore insulin production in type 1 and some type 2 diabetics.

Related Conferences:

15thWorld Congress on Biotechnology and Biotech Industries Meet ,Rome, Italy,March 20-21, 2017;6th International Conference onTissue Engineering & Regenerative Medicine, Baltimore, USA, Aug 20-22, 2017; 8th World Congress and Expo onCell & Stem Cell Research, Orlando, USA, March 20-22, 2017; 14th Asia-Pacific Biotech Congress,Beijing, China,April 10-12, 2017;5th International Conference onIntegrative Biology, London, UK, June 19-21, 2017.

Track-10 Viral gene therapy:

Converting avirusinto a vector Theviral life cyclecan be divided into two temporally distinct phases: infection and replication. Forgene therapyto be successful, an appropriate amount of a therapeutic gene must be delivered into the target tissue without substantial toxicity. Eachviral vectorsystem is characterized by an inherent set of properties that affect its suitability for specific gene therapy applications. For some disorders, long-term expression from a relatively small proportion of cells would be sufficient (for example, genetic disorders), whereas otherpathologiesmight require high, but transient,gene expression. For example, gene therapies designed to interfere with a viral infectious process or inhibit the growth ofcancer cellsby reconstitution of inactivated tumour suppressor genes may require gene transfer into a large fraction of theabnormal cells.

Related Conferences:

3rd International Conference onSynthetic Biology, Munich, Germany, July 20-21, 2017;5th International Conference and Exhibition onCell and Gene Therapy,Madrid, Spain,Mar 2-3, 2017; International Conference on Animal and Human Cell Culture, Jackson Ville, USA, Sep 25-27, 2017; 9th International Conference onCancer Genomics, Chicago, USA, May 29-31, 2017; 14th Asia-Pacific Biotech Congress,Beijing, China,April 10-12, 2017.

Track-11 Stem cell therapies:

Stem cells have tremendous promise to help us understand and treat a range of diseases, injuries and other health-related conditions. Their potential is evident in the use ofblood stem cellsto treat diseases of the blood, a therapy that has saved the lives of thousands of children withleukaemia; and can be seen in the use ofstem cellsfor tissue grafts to treat diseases or injury to the bone, skin and surface of the eye. Some bone, skin andcorneal(eye) injuries and diseases can be treated bygraftingor implanting tissues, and the healing process relies on stem cells within thisimplanted tissue.

Related Conferences:

2nd World Congress on Human Genetics, Chicago, USA, July 24-26, 2017; 2nd International Conference onGenetic Counselling and Genomic Medicine ,Beijing, China,July 10-12, 2017; International Conference onClinical and Molecular Genetics, Las Vegas, USA, April 24-26, 2017; 2nd International Conference onMolecular Biology,London, UK,June 22-24, 2017; 15th Biotechnology Congress, Baltimore, USA, June 22-23, 2017.

Track-12 Stem cell preservation:

The ability to preserve the cells is critical to theirclinicalapplication. It improves patient access to therapies by increasing the genetic diversity of cells available. In addition, the ability to preserve cells improves the "manufacturability" of acell therapyproduct by permitting the cells to be stored until the patient is ready for administration of the therapy, permitting inventory control of products, and improving management of staffing atcell therapyfacilities. Finally, the ability to preservecell therapiesimproves the safety of cell therapy products by extending the shelf life of a product and permitting completion of safety and quality control testing before release of the product for use. preservation permits coordination between the manufacture of the therapy and patient care regimes.

Related Conferences:

7th Annual Conference on Stem Cell and Regenerative Medicine,Paris, France,Aug 04-05, 2016; 2nd Biotechnology World Convention,LONDON, UK,May 25-27, 2017; International Conference on Animal and Human Cell Culture, Jackson Ville, USA, Sep 25-27, 2017; 9th International Conference onCancer Genomics, Chicago, USA, May 29-31, 2017; 3rd International Conference onSynthetic Biology, Munich, Germany, July 20-21, 2017.

Track-13 Stem cell products:

The globalstemcell,Stem cell productsmarket will grow from about $5.6 billion in 2013 to nearly $10.6 billion in 2018, registering a compound annual growth rate (CAGR) of 13.6% from 2013 through 2018.This trackdiscusses the implications ofstemcellresearchand commercial trends in the context of the current size and growth of thepharmaceutical market, both in global terms and analysed by the most important national markets.

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6th International Conference onTissue Engineering & Regenerative Medicine, Baltimore, USA, Aug 20-22, 2017; 8th World Congress and Expo onCell & Stem Cell Research, Orlando, USA, March 20-22, 2017; 15thWorld Congress on Biotechnology and Biotech Industries Meet,Rome, Italy,March 20-21, 2017; 2nd International Conference onGenetic Counselling and Genomic Medicine ,Beijing, China,July 10-12, 2017; International Conference onClinical and Molecular Genetics, las vegas, USA, April 24-26, 2017.

Track-14 Genetically inherited diseases:

Agenetic diseaseis any disease that is caused by an abnormality in an individual'sgenome, the person's entiregeneticmakeup. The abnormality can range from minuscule to major -- from a discrete mutation in a single base in the DNA of a single gene to a grosschromosome abnormalityinvolving the addition or subtraction of an entirechromosomeor set of chromosomes.Most genetic diseases are the direct result of a mutation in one gene. However, one of the most difficult problems ahead is to find out how genes contribute to diseases that have a complex pattern ofinheritance, such as in the cases of diabetes,asthma,cancerandmental illness. In all these cases, no one gene has the yes/no power to say whether a person has a disease or not. It is likely that more than one mutation is required before the disease is manifest, and a number of genes may each make a subtle contribution to a person's susceptibility to a disease; genes may also affect how a person reacts toenvironmental factors.

Related Conferences:

15th Biotechnology Congress, Baltimore, USA, June 22-23, 2017; 3rd International Conference onSynthetic Biology, Munich, Germany, July 20-21, 2017; 5th International Conference and Exhibition onCell and Gene Therapy,Madrid, Spain,Mar 2-3, 2017; International Conference onCell Signalling and Cancer Therapy,paris, France,Aug 20-22, 2017; International Conference on Animal and Human Cell Culture, Jackson Ville, USA, Sep 25-27, 2017.

Track-15 Plant stem cells:

Plantshave emerged as powerful production platforms for the expression of fully functional recombinantmammalian proteins. These expression systems have demonstrated the ability to produce complexglycoproteinsin a cost-efficient manner at large scale. The full realization of thetherapeuticpotential of stem cells has only recently come into the forefront ofregenerative medicine. Stem cells are unprogrammed cells that can differentiate into cells with specific functions.Regenerative therapiesare used to stimulate healing and might be used in the future to treat various kinds of diseases.Regenerative medicinewill result in an extended healthy life span. A fresh apple is a symbol for beautiful skin. Hair greying for example could be shown to result from the fact that themelanocyte stem cellsin the hair follicle have died off.

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9th International Conference onGenomics and Pharmacogenomics, Chicago, USA, July 13-14, 2017; 7th International Conference onPlant Genomics, Bangkok, Thailand, July 03-05, 2017; 15th Euro Biotechnology Congress, Valencia, Spain, June 05-07, 2017; 5th International Conference and Exhibition onCell and Gene Therapy,Madrid, Spain,Mar 2-3, 2017; 3rd International Conference & Exhibition onTissue Preservation and Bio banking,Baltimore, USA,June 29-30, 2017.

Track-16 Plant stem cell rejuvenation:

Asplantscannot escape from danger by running or taking flight, they need a special mechanism to withstandenvironmental stress. What empowers them to withstand harsh attacks and preserve life is the stem cell. According to Wikipedia, plantstem cellsnever undergo theagingprocess but constantly create new specialized and unspecialized cells, and they have the potential to grow into any organ, tissue, or cell in the body. The everlasting life is due to the hormones auxin andgibberellin. British scientists found that plant stem cells were much more sensitive toDNAdamage than other cells. And once they sense damage, they trigger death of these cells.

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Track-17 Clinical trials in cell and gene therapy:

Aclinical trialis a research study that seeks to determine if a treatment is safe and effective. Advancing new cell andgene therapies(CGTs) from the laboratory into early-phaseclinical trialshas proven to be a complex task even for experienced investigators. Due to the wide variety ofCGTproducts and their potential applications, a case-by-case assessment is warranted for the design of each clinical trial.

Objectives:Determine thepharmacokineticsof this regimen by the persistence of modified T cells in the blood of these patients, Evaluate theimmunogenicityof murine sequences in chimeric anti-CEA Ig TCR, Assess immunologic parameters which correlate with the efficacy of this regimen in these patients, Evaluate, in a preliminary manner, the efficacy of this regimen in patients with CEA bearingtumours.

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Track-18 Molecular epigenetics:

Epigeneticsis the study of heritable changes in thephenotypeof a cell or organism that are not caused by its genotype. The molecular basis of anepigeneticprofile arises from covalent modifications of protein andDNAcomponents ofchromatin. The epigenetic profile of a cell often dictates cell fate, as well as mammalian development,agingand disease. Epigenetics has evolved to become the science that explains how the differences in the patterns ofgene expressionin diverse cells or tissues are executed and inherited.

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Track-19 Bioengineering therapeutics:

The goals ofbioengineeringstrategies for targetedcancertherapies are (1) to deliver a high dose of an anticancer drug directly to a cancer tumour, (2) to enhance drug uptake by malignant cells, and (3) to minimize drug uptake by non-malignant cells. In ESRD micro electro mechanical systems andnanotechnologyto create components such as robust silicon Nano pore filters that mimic natural kidney structure for high-efficiency toxin clearance. It also usestissue engineeringto build a miniature bioreactor in which immune-isolated human-derived renal cells perform key functions, such as reabsorption of water and salts.In drug delivery for a leading cause ofblindness, photo-etching fabrication techniques from themicrochipindustry to create thin-film and planar micro devices (dimensions in millionths of meters) with protectivemedicationreservoirs andnanopores(measured in billionths of meters) for insertion in the back of the eye to deliver sustained doses of drug across protective retinalepithelial tissuesover the course of several months.

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6th International Conference onTissue Engineering & Regenerative Medicine, Baltimore, USA, Aug 20-22, 2017; 8th World Congress and Expo onCell & Stem Cell Research, Orlando, USA, March 20-22, 2017; 15thWorld Congress on Biotechnology and Biotech Industries Meet,Rome, Italy,March 20-21, 2017; 2nd International Conference onGenetic Counselling and Genomic Medicine ,Beijing, China,July 10-12, 2017; International Conference onClinical and Molecular Genetics, Las Vegas, USA, April 24-26, 2017.

Track-20 Advanced gene therapy:

Advanced therapiesare different fromconventional medicines, which are made from chemicals or proteins.Gene-therapymedicines:these contain genes that lead to atherapeuticeffect. They work by inserting 'recombinant' genes into cells, usually to treat a variety of diseases, including genetic disorders, cancer or long-term diseases.Somatic-cell therapymedicines:these contain cells or tissues that have been manipulated to change their biological characteristics.Advanced Cell &Gene Therapyprovides guidanceinprocess development, GMP/GTP manufacturing,regulatory affairs, due diligence and strategy, specializing in cell therapy,gene therapy, and tissue-engineeredregenerative medicineproducts.

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What Explains the Collapse of the USSR?

Posted: August 23, 2016 at 9:34 am

A Critical Analysis into the Different Approaches Explaining the Collapse of the Soviet Union: Was the Nature of the Regimes Collapse Ontological, Conjunctural or Decisional?

Abstract

This investigation seeks to explore the different approaches behind the demise of the Soviet Union. It will draw from Richard Sakwas three approaches with regards to the collapse of the Soviet Union, namely of the ontological, decisional and conjunctural varieties. This dissertation will ultimately demonstrate the necessity of each of these if a complete understanding of the demise is to be acquired.

This dissertation will be split into three different areas of scrutiny with each analysing a different approach. The first chapter will question what elements of the collapse were ontological and will consist of delving into long-term socio-economic and political factors in order to grasp what structural flaws hindered the Soviet Union from its inception. Following this will be an analysis of the decisional approach, this time focusing on short-term factors and how the decisions of Gorbachev contributed to the fall. Finally, this investigation will examine the conjunctural approach, which will provide valuable insight as to how short-term political contingent factors played a leading role in the eventual ruin of the Soviet Union.

Introduction

On December 26th, 1991, the Soviet Union was officially dissolved into fifteen independent republics after six years of political-economic crises. This unanticipated collapse of a super-power that had once shaped the foreign policies of East and West took the international community off-guard. Since the collapse, scholars have attempted to provide insight into the reasons behind the demise of the Soviet state. In 1998 Richard Sakwa published Soviet Politics in Perspective, which categorised the three main approaches adopted by scholars in the study of the collapse of the Union of Soviet Socialist Republics (USSR). These were the ontological, decisional and conjunctural approaches and will be the foci of this investigation. Ultimately, my aim is to prove that none of these approaches can thoroughly explain the collapse when viewed individually.

Instead, I will advance that all three are vital in order to acquire a thorough understanding of the Soviet collapse. To prove this, I will be analysing how each approach covers different angles of the fall, but before being able to answer this question of validity, I must begin by arranging each scholar I scrutinize into Sakwas three approaches. In my research I have discovered that the vast majority of scholars have no notion of such schools of thought, which increases the possibility of bias in secondary sources and makes my investigation all the more challenging. Once a solid theoretical basis is set I will then move onto investigating the legitimacy of each approach when considering historical events.

Research Questions

To provide the basis for my hypothesis, my analysis will be subdivided into three research questions.

The first one will address what ontological traits existed in the collapse of the Soviet Union. Following this, the second question will mirror the first by attempting to make sense of decisional aspects of the fall. Finally, my attention will turn to answering in what way was the collapse conjunctural in nature. Although the characteristics of these questions may seem basic it is important not to fall prey to appearances and bear in mind the complexity of each approach. Moreover, the arrangement and formulation of the research questions was carried out in this manner to provide an unbiased evaluation of each approach, eventually displaying the necessity of each in the explanation of fall.

Methodology

The fall of the Soviet Union is a subject that has attracted vast amounts of literature from scholars all over the world. Although this presents a challenge when it comes to working through such a large topic it also helps the researcher elaborate solid explanations behind historical events. Consequently, I will be mainly employing qualitative data, supplemented by quantitative evidence; which will consist of both primary and secondary sources. The quantitative information will draw from various economists such as Lane, Shaffer and Dyker; these will mainly be used to ensure that qualitative explanations are properly backed by statistical data regarding socio-economic factors.

The majority of the qualitative data drawn will be from secondary sources written by contemporary scholars. A few primary sources such as official documents will also be analysed to provide further depth to analysis. Due to the vast amount of information concerning my topic, it is important to focus on literature aiding the question as one can easily deviate from the question regarding the three approaches. The other main challenge will also consist in avoiding to be drawn into deep analysis of the separate independence movements of the Soviet republics.

Theoretical Framework

Before being able to embark on a complete literature review, it is important to understand the theoretical framework that accompanies the analysis, namely Sakwas three approaches. Subsequently, I will then be able to show that all three of these approaches are necessary in explaining the downfall of the Soviet Union.

When looking at the different approaches elaborated by Sakwa, each advances a unique hypothesis as to why the Soviet Union collapsed. Although all three approaches are different in nature, some overlap or inter-connect at times. To begin with, the ontological approach argues that the Soviet Union dissolved because of certain inherent shortcomings of the system [] including [] structural flaws.[1] This approach enhances the premise that the collapse of the Soviet Union lies in long-term systemic factors that were present since the conception of the system. This view is countered by the conjunctural approach, which suggests

that the system did have an evolutionary potential that might have allowed it in time to adapt to changing economic and political circumstances. [] The collapse of the system [is] ascribed to contingent factors, including the strength of internal party opposition [and] the alleged opportunism of the Russian leadership under Boris Yeltsin.[2]

The final approach theorised by Sakwa is the decisional one, and advances the belief that

particular decisions at particular times precipitated the collapse, but that these political choices were made in the context of a system that could only be made viable through transformation of social, economic and political relations. This transformation could have been a long-term gradual process, but required a genuine understanding of the needs of the country.[3]

Although the decisional and conjunctural approaches are different in scope, they nevertheless both focus on the short-term factors of collapse, which at times may cause confusions. As both approaches analyse the same time frame, certain factors behind the collapse may be logically attributed to both. A relevant example may be seen when a contingent factor (factions within the Communist Party) affects the decisions of a leader (Gorbachev). This leads to ambiguities, as it is impossible to know whether certain outcomes should be explained in a conjunctural or decisional light. This type of ambiguity can also cast doubts on certain conjunctural phenomena with historical antecedents. In these cases it becomes unclear as to whether these phenomena are ontological (structural), as they existed since the systems conception or conjunctural as they present contingent obstacles to progress.

In most cases, when ambiguities arise, scholars may adopt a rhetoric that is inherently ontological, decisional or conjunctural and then base most of their judgements and analysis around it. Kalashnikov supplements this, stating that studies tend to opt for one factor as being most important in bringing about collapse [] [and] do not engage other standpoints.[4] This is a trait I have noticed in certain works that were written by scholars more inclined to analyse events through a certain approach, such as Kotkin with the ontological approach, Goldman with the decisional one, or Steele regarding the conjunctural approach. In my analysis, I will scrutinise the fall through the theoretical lens of each approach, and from this will prove the indispensability of each of these in the explanation of the downfall. The fact that certain approaches overlap is testament to the necessity of this theoretical categorisation.

Literature Review

The first approach to be investigated will be the ontological one: a school of thought espoused by scholars who focus on systemic long-term factors of collapse. Kotkin is one such author, providing valuable insight into the ontological dissolution of Soviet ideology and society, which will figure as the first element of analysis in that chapter. He advances the theory that the Soviet Union was condemned from an early age due to its ideological duty in providing a better alternative to capitalism. From its inception, the Soviet Union had claimed to be an experiment in socialism []. If socialism was not superior to capitalism, its existence could not be justified.[5] Kotkin elaborates that ideological credibility crumbled from the beginning as the USSR failed to fulfil expectations during Stalins post-war leadership. Kotkin goes on and couples ideological deterioration with emphasis on societal non-reforming tendency that flourished after the 1921 ban on factions, setting a precedent where reform was ironically seen as a form of anti-revolutionary dissidence.

Kenez and Sakwa also supplement the above argument with insight on the suppression of critical political thinking, notably in Soviet satellite states, showing that any possibility of reforming towards a more viable Communist rhetoric was stifled early on and continuously supressed throughout the 1950s and 60s. This characteristic of non-reform can be seen as an ontological centre-point, as after the brutal repression seen in Hungary (1956) and Czechoslovakia (1968), no feedback mechanism existed wherein leadership could comprehend the social, political and economic problems that were gradually amassing. The invasion of 1968 represented the destruction of the sources of renewal within the Soviet system itself.[6] Consequently, this led the Kremlin into a state of somewhat ignorance vis--vis the reality of life in the Soviet Union. Adding to the explanation of the Soviet Unions ontological demise, Sakwa links the tendency of non-reform to the overlapping of party and polity that occurred in the leadership structure of the USSR. The CPSU was in effect a parallel administration, shadowing the official departments of state: a party-state emerged undermining the functional adaptability of both.[7] Sakwa then develops that this led to the mis-modernisation of the command structure of the country, and coupled with non-reform, contributed to its demise. Furthermore, ontologically tending scholars also view the republican independence movements of the USSR as a factor destined to occur since the conception of the union.

The second section concerning the ontological approach analyses the economic factors of collapse. Here, Derbyshire, Kotkin and Remnick provide a quantitative and qualitative explanation of the failure of centralisation in the agricultural and industrial sectors. Derbyshire and Remnick also provide conclusive insight into ontological reasons for the failure of industrial and agricultural collectivization, which played a leading role in the overall demise of the Soviet Union.

Finally, in my third area of investigation, Remnick and Sakwa claim that the dissolution came about due to widespread discontent in individual republics regarding exploitation of their natural resources as well as Stalins detrimental policy of pitting different republics against each other.

Moscow had turned all of Central Asia into a vast cotton plantation [] [and in] the Baltic States, the official discovery of the secret protocols to the Nazi-Soviet pact was the key moment.[8]

Although I will explore how independence movements played a role in the dissolution, I will ensure the focus remains on the USSR as a whole, as it is easy to digress due to the sheer amount of information on independence movements. Upon this, although evidence proves that certain factors of collapse were long-term ontological ones, other scholars, namely Goldman and Galeotti go in another direction and accentuate that the key to understanding the downfall of the USSR lies in the analysis of short-term factors such as the decisional approach.

Dissimilar to the ontological approach, within the decisional realm, scholars more frequently ascribe the factors of the collapse to certain events or movements, which allows them to have minute precision in their explanations of the fall. Goldman is a full-fledged decisional scholar with the conviction that Gorbachev orchestrated the collapse through his lack of comprehensive approach,[9] a view espousing Sakwas definition of the decisional approach. In order to allow for a comprehensive analysis, this chapter will start off with an examination of Gorbachevs economic reforms in chronological order, allowing the reader to be guided through the decisions that affected the collapse. Goldman will be the main literary pillar of this section, supplemented by Sakwa and Galeotti. Having accomplished this, it will be possible to investigate how economic failure inter-linked with political decisions (Glasnost and Perestroika) outside of the Party created an aura of social turmoil. Here, Galeotti and Goldman will look into the events and more importantly, the decisions, that discredited Gorbachevs rule and created disillusion in Soviet society. My final section of the chapter will scrutinize the affects of Glasnost and Perestroika within the Communist Party, which will stand as a primordial step in light of the independence movements; seen as a by-product of Gorbachevs policies. Due to the inter-linked nature of the political, social and economic spheres, it will be possible to see how policy sectors affected each other in the collapse of the Soviet Union.

Overall, this chapter will end with an analysis of how Gorbachevs incoherence pushed certain republics onto the path of independence, which is perceived as a major factor behind the fall by Goldman.

In the chapter regarding the conjunctural approach, I will be looking into the key contingent factors that scholars believe are behind the fall of the Soviet Union. The first will be the conservatives of the Communist Party who obstructed the reform process since Brezhnevs rule, meaning that up until the collapse, reform efforts had run headlong into the opposition of entrenched bureaucratic interests who resisted any threat to their power.[10] Due to the broadness of this topic I will draw from two scholars, namely Kelley and Remnick, for supplementary insight. Moving on, I will also investigate the inception of the reformist left, a term encapsulating those within and outside the party striving to bring democratic reform to the USSR. Here the main conjunctural scholar used will be Steele, who explains that Gorbachevs hopes for this reformist left to support him against the Communist conservatives evaporated once Yeltsin took the lead and crossed the boundaries of socialist pluralism set by Gorbachev. A concept coined by the leader himself, which implied that there should be a wide exchange of views and organizations, provided they all accepted socialism.[11] This brought about enormous pressure and sapped social support from Gorbachev at a time when he needed political backing. Once the political scene is evaluated through conjunctural evidence, I will divide my chapter chronologically, first exploring the 1989 radicalisation of the political movements with the significant arrival of Yeltsin as the major obstacle to Gorbachevs reforms to the left. In this section I will be mainly citing Remnick due to his detailed accounts of events. Ultimately I will be attempting to vary my analysis with approach-specific scholars and more neutral ones who provide thorough accounts, such as Remnicks and Sakwas. The analysis will continue with insight in the 1990-1991 period of political turmoil and the effects it had on Gorbachevs reforms; I will be citing Galeotti, Remnick and Tedstrom as these provide varying viewpoints regarding political changes of the time. My chapter will then finally end with a scrutiny of Yeltsins Democratic Russia and the August 1991 Coup and how both of these independent action groups operated as mutual contingent factors in the dissolution of the Soviet Union.

Chapter One: Was the Collapse of the USSR Ontological in Nature?

When analysing the collapse of the USSR, it is undeniable that vital ontological problems took form during the early days of its foundation. Here I will analyse these flaws and demonstrate how the collapse occurred due to ontological reasons, hence proving the necessity of this approach. In order to provide a concrete answer I will begin by scrutinizing how the erosion of the Communist ideology acted as a systemic flaw where the Soviet Unions legitimacy was put into question. I will then analyse how a non-reformist tendency was created in society and also acted as an ontological flaw that would play a part in the fall. From there I will explore how ontological defects plagued the economic sector in the industrial and agricultural areas, leading the country to the brink of economic collapse. Finally I will analyse the independence movements, as certain scholars, especially Remnick and Kotkin, argue that these movements pushed towards ontological dissolution. It is imperative to recall that this chapter will analyse symptoms of the collapse that are of an ontological nature, namely long-term issues that manifested themselves in a negative manner on the longevity of the Soviet Union. As a result it is vital to bear in mind that the ontological factors to be analysed are usually seen as having all progressively converged together over the decades, provoking the cataclysmic collapse.

The Untimely Death of an Ideology

Since its early days, the Soviet Union was a political-economic experiment built to prove that the Communist-Socialist ideology could rival and even overtake Capitalism. It promoted itself as a superior model, and thus was condemned to surpassing capitalism if it did not want to lose its legitimacy. However, during Stalins tenure, the ideological legitimacy of the Soviet Union crumbled due to two reasons: the first one being the aforementioned premiers rule and the other being Capitalisms success, which both ultimately played a part in its demise.

The early leaders of the Communist Party of the Soviet Union (CPSU) such as Lenin, Trotsky, Kamenev, Bukharin, Zinoviev and Stalin all had different views regarding how to attain socio-economic prosperity, but Stalin would silence these after the 1921 to 1924 power struggle. Following this period, which saw the death of Lenin, Stalin emerged as the supreme leader of the Soviet Union. With the exile of Trotsky, and isolation of Zinoviev, Kamenev and Bukharin from the party, no effective opposition was left to obstruct the arrival of Stalins fledging dictatorship. Subsequently, Stalin was able to go about effectively appropriating the Communist ideology for himself; with his personality cult he became the sole curator of what was Communist or reactionary (anti-Communist). Subsequently, to protect his hold on power, he turned the Soviet Union away from Marxist Communist internationalism by introducing his doctrine of Socialism in One Country, after Lenins death in 1924.

Insisting that Soviet Russia could [] begin the building of socialism [] by its own efforts. [] [Thus treading on] Marxs view that socialism was an international socialist movement or nothing.[12]

As a result, the USSR under Stalin alienated the possibilities of ideological renewal with other Communist states and even went as far as to claim, that the interests of the Soviet Union were the interests of socialism.[13] Sakwa sees these actions as ones that locked the Soviet Union into a Stalinist mind-set early on and thus built the wrong ideological mechanisms that halted the advent of Communist ideology according to Marx. As a result, it is fair to acknowledge that when looking at ontological reasons for collapse, one of them can be mentioned as the Soviet Union being built upon an ambiguous ideological platform wherein it espoused elements of Communism but was severely tainted and handicapped by Stalinist rhetoric.

In addition to the debilitating effects Stalins political manipulations had on the ideological foundations of the USSR, capitalisms successful reform dealt a supplementary blow to Soviet ideological credibility.

Instead of a final economic crisis anticipated by Stalin and others, Capitalism experienced an unprecedented boom [] all leading capitalist countries embraced the welfare state [] stabilising their social orders and challenging Socialism on its own turf.[14]

Adding to the changing nature of capitalism was the onset of de-colonisation during the 1960s, taking away more legitimacy with every new independence agreement. By the end of the 1960s, the metamorphosis of capitalism had very much undermined the Soviet Unions ideological raison dtre, as the differences between capitalism in the Great Depression [which the USSR had moulded itself against,] and capitalism in the post-war world were nothing short of earth shattering.[15] Here the ontological approach generally elaborates that Capitalism and incoherent ideological foundations brought about the disproving of the very political foundations the Soviet state rested upon and thus any social unrest leading to the collapse during Gorbachevs rule can be interpreted as logical by-products of the previous point. From this, it is possible to better understand how the crumbling of the legitimacy of the Communist ideology was a fundamental ontological factor behind the collapse of the USSR. Building on this, I will now look into how the establishment of society during Stalins rule also played a role in the collapse due to the shaping of a non-reforming society.

The Foundations of a Non-Reforming Society

One defect that would remain etched in the Soviet political-economic mind-set was the ontological tendency for non-reform. This trait would plague the very infrastructure of the Soviet Union until its dying days. The emergence of such a debilitating characteristic appeared during the very inception of the Soviet Union with the Kronstadt Sailors Uprising. This uprising occurred during the Tenth Party Congress in 1921 and would have severe repercussion for the Soviet Unions future as Congress delegates [] accepted a resolution that outlawed factions within the Party.[16] Thus, by stifling critical thinking and opposing views, this would effectively cancel out a major source of reform and act as an ontological shortcoming for future Soviet political-economic progress. This non-reformist trait was reinforced during Stalins rule with the constant pressure the Communist Party exerted on agricultural and industrial planners. Here, the party demanded not careful planning [] but enthusiasm; the leaders considered it treason when economists pointed out irrationalities in their plans.[17] Subsequently, planners were forced into a habit of drawing up unmanageable targets, which were within the partys political dictate. This meant, central planners established planning targets that could only be achieved at enormous human cost and sacrifice. [] [and lacked] effective feedback mechanism[18], which would provide insight to the flaws that existed in their plans. In the short-run this would only hinder the economy, but in the long-term it would lock the Soviet Union in a tangent where it could not reform itself in accordance to existent problems[19], thus leading it to a practically technologically obsolete state with a backwards economy by the time it collapsed.

Nevertheless, repression of critical thinking did not limit itself to the economic realm; it also occurred in the social sector where calls for the reform of the Socialist ideology were mercilessly crushed in Hungary in 1956 and in Czechoslovakia in 1968. It is possible to see a link here with the previous section of this chapter with regards to Stalins hijacking of the Communist ideology. In the two social movements cited, both pushed towards a shift away from Stalinist rhetoric towards an actual adoption of Marxist Socialism. In Czechoslovakia this social push came under the name of Socialism with a Human Face and wanted to permit the dynamic development of socialist social relations, combine broad democracy with a scientific, highly qualified management, [and] strengthen the social order.[20] Although these were only Soviet satellite states, the fact that they were repressed showed that by the 1960s, the Soviet Unions non-reforming characteristic had consolidated itself to the point that any divergence from the official party line in the economic or social sectors was seen as high treason. This leads us to the ambiguous area of Soviet polity and how it jeopardised the existence of the USSR when merged with ontological non-reform.

Polity is the term I use here because it remains implausibly unclear as to who essentially governed the USSR during its sixty-nine years of existence. It seems that both the CPSU and the Soviet government occupied the same position of authority, thus creating

a permanent crisis of governance. [Wherein] the party itself was never designed as an instrument of government and the formulation that the party rules but the government governs allowed endless overlapping jurisdictions.[21]

Adding to the confusion was the CPSUs role in society, defined by Article Six of the USSRs 1977 Constitution: The leading and guiding force of the Soviet society and the nucleus of its political system, of all state organisations and public organisations, is the Communist Party of the Soviet Union.[22] From here a profound ambiguity is seen surrounding the role of politics in the social realm. Accordingly, these two traits would create a profound ontological factor for collapse when merged with the non-reforming tendency of society. Due to the fact that when a more efficient leadership mechanism was sought out, it was impossible to identify how and what elements of the polity had to be changed.

It is here that an inter-linkage of approaches can be identified as the politys ontological inability to reform according to Gorbachevs decisional re-shaping of society contributed to the demise of the USSR.

The one-party regime ultimately fell owing to its inability to respond to immense social changes that had taken place in Soviet society- ironically, social changes that the Party itself had set in motion.[23]

Because Soviet polity was ontologically ill defined, when time came to reform it, the notion of what was to be changed obstructed the reform process. From this analysis, it is possible to see how ontological weaknesses in the over-lapping areas of politics and the social sector seriously hindered the Soviet Union. In the following section I will explore how ontological defects were of similar importance in the economic realm and were also interwoven with previously explained shortcomings.

An Economy in Perpetual Crisis

When looking at the economic realm there are a number of weaknesses that took root from the early days of the Soviet Union, the first aspect of scrutiny will be the ontological failure of economic centralisation and its contribution to the fall. In both the agricultural and industrial sectors, the USSR was unable to progress towards economic prosperity due to its flawed centralised economy. Agriculturally, centralisation meant that peasants were compelled to fulfil farming quotas set by the ministry in Moscow on land that solely belonged to the state. Consequently this generated two problems, the first one being a lack of incentive from the farmers and secondly, the inability of central authorities to cope with the myriad of different orders that had to be issued.

Central planners in Moscow seldom know in advance what needs to be done in the different regions of the country. Because of this [] sometimes as much as 40 to 50 per cent of some crops rot in the field or in the distribution process.[24]

Worsening this was the partys non-reforming tendency, which meant that the Soviet Union protected its misconceived collective and state farming network and made up for its agricultural ineptness by importing up to 20 per cent of the grain it needed.[25] This patching-up of ontological agricultural problems would result in an unpredictable and inconsistent agricultural sector as the decades passed, thus rendering it unreliable. This can be seen in the post-war agricultural growth rates that continuously fluctuated from 13.8 per cent in 1955 to -1.5 per cent in 1959 and finally -12.8 per cent in 1963![26] Such a notoriously unpredictable agricultural sector [] consistently failed to meet planned targets[27] and would remain an unresolved problem until the fall of the regime.

As for the industrial sector, the situation was difficult; with the disappearance of a demand and supply mechanism, the central authorities were unable to properly satisfy the material demands of society. Moreover, because of centralisation, most factories were the sole manufacturers of certain products in the whole of the USSR, meaning that an enormous amount of time and money was wasted in transport-logistics costs. Without the demand and supply mechanism, the whole economy had to be planned by central authorities, which proved to be excruciatingly difficult.

Prices of inputs and outputs, the sources of supply, and markets for sale were strictly stipulated by the central ministries. [] [and] detailed regulation of factory level activities by remote ministries [] led to a dangerously narrow view of priorities at factory level.[28]

Consequently, central ministries frequently misallocated resources and factories took advantage of this by hoarding larger quantities of raw materials than they needed. Although the ontological failure of centralisation did not have as immediate effects as certain short-term conjunctural or decisional factors, its contribution to the fall can be seen in how, combined with the economic shortcomings to be highlighted hereon, it gradually deteriorated the economy of the country.

In addition to the failure of centralisation was the failure of agricultural collectivization, which would have an even greater negative effect on the Soviet Union. When looking at collectivization we can see how its affects were multi-layered, as it was a politically motivated campaign that would socially harm society and destroy the economy. Agriculturally, Stalin hindered the Soviet farming complex from its very beginnings by forcing collectivisation on farmers and publicly antagonising those who resisted as anti-revolutionary kulaks. After the winter of 1929, Stalin defined the meaning of kulak as anyone refusing to enter collectives. Kulaks were subsequently persecuted and sent to Siberian gulags, the attack on the kulaks was an essential element in coercing the peasants to give up their farms.[29] These repeated attacks came from a Bolshevik perception that peasants were regarded with suspicion as prone to petty-bourgeois individualist leanings.[30] Due to these traumatic acts of violence, the peasantry was entirely driven into collectivisation by 1937; however, this only bolstered peasant hatred of the government and can be seen as the basis for the agricultural problem of rural depopulation that gradually encroached the country-side. By the 1980s,

The legacy of collectivization was everywhere in the Soviet Union. In the Vologda region alone, there were more than seven thousand ruined villages [] For decades, the young had been abandoning the wasted villages in droves.[31]

This agricultural depopulation can be seen in how the number of collective farms gradually shrank from 235,500 in 1940 to merely 25,900 in 1981[32]; causing severe labour scarcity concerns to the agricultural sector.

Industrially, collectivisation was not widespread, although in the few cases it appeared, it brought about much suffering to yield positive results. The mining city of Magnitogorsk is a prime example where Stalinist planners

built an autonomous company town [] that pushed away every cultural, economic, and political development in the civilized world [and where] 90 per cent of the children [] suffered from pollution-related illnesses.[33]

While the West followed the spectacular expansion of Soviet industry from 1920 to 1975, this was at the cost of immense social sacrifice in the industrial and agricultural sectors, which were entirely geared towards aiding the industrial complex. In addition to this, much of Soviet industrial growth after Khrushchevs rule was fuelled by oil profits emanating from Siberia, peaking from 1973 to 1985 when energy exports accounted for 80% of the USSRs expanding hard currency earnings.[34]

Overall, ontological non-reform inter-linked with the failure of collectivisation and a deficient command structure would gradually weaken the economy to the brink of collapse in the 1980s. This elaboration was made clear in the 1983 Novosibirsk Report, which

argued that the system of management created for the old-style command economy of fifty years ago remained in operation in very different circumstances. It now held back the further development of the countrys economy.[35]

Nevertheless, ontological problems behind the fall did not only restrict themselves to the economic, political or social realms but also existed regarding the nationalities question.

A Defective Union

When looking at the fifteen different republics that comprised the USSR, one may ask how it was possible to unite such diverse nationalities together without the emergence of complications. The truth behind this is that many problems arose from this union even though the CPSU maintained, until the very end, the conviction that all republics and people were acquiescent of it. Gorbachevs statement in 1987 that

the nationalities issue has been resolved for our country [] reflected the partys most suicidal illusion, that it had truly created [] a multinational state in which dozens of nationalisms had been dissolved.[36]

Today certain scholars see the independence movements of the early 1990s as a result of the ontological malformation of the Soviet Unions identity. The most common argument expounds that the independence movements fuelling dissolution occurred due to two ontological reasons. The first one can be seen as a consequence of Stalins rule and as part of his policy of divide and rule, where the borders between ethno-federal units were often demarcated precisely to cause maximum aggravation between peoples.[37] This contributed to the Soviet Unions inability to construct a worthwhile federal polity and an actual Soviet nation-state. In addition to this was the ontological exploitation of central Soviet republics and prioritisation of the Russian state. This created long-term republican discontent that laid the foundations of independence movements: Everything that went wrong with the Soviet system over the decades was magnified in Central Asia,[38] Moscow had turned all of Central Asia into a vast cotton plantation [] destroying the Aral Sea and nearly every other area of the economy.[39]

Overall, it is possible to argue that the collapse occurred due to inherent flaws in the foundations of the Soviet Union. Ontological factors behind the collapse were an admixture of socio-political and economic weaknesses that gradually wore at the foundations of the USSR. The first area analysed was the demise of the Marxist ideology that up-held the legitimacy of the Soviet Union. I then scrutinized the non-reforming tendency that settled in Soviet society very early on. Such an area eventually brought me to inspect the ontological flaws in Soviet economy, which had close links with the previous section. Finally, I examined inherent flaws in the USSRs union and how these also played a role in the demise. While the ontological factors represent a substantial part of the explanation to the downfall, decisional and conjunctural factors must also be examined to fully grasp the collapse.

Chapter Two: Was the Collapse of the USSR Decisional in Nature?

Whilst long-term flaws in the foundations of the Soviet Union played a major role in its demise, it is important to acknowledge that most of Gorbachevs reforms also had drastic effects on the survival of the union. From hereon, I will explore how the decisional approach explains vital short-term factors behind the collapse and cannot be forgone when pondering this dissertations thesis-question. To begin with, I will analyse the failure of Gorbachevs two major economic initiatives known as Uskoreniye (acceleration of economic reforms) and Perestroika. This will then inevitably lead me to the scrutiny of his socio-political reforms under Glasnost and how imprudent decisions in this sector led to widespread unrest in the USSR. Finally I will look into how Gorbachevs decisional errors led to most republics to opt out of the Soviet Union. But before I start it is important to understand that although I will be separating the economic reforms (Uskoreniye and Perestroika), from socio-political ones (Glasnost), these were very much intertwined as Gorbachev saw them as mutually complementary.

A Botched Uskoreniye and an Ineffective Perestroika

By the time Gorbachev rose to power in March 1985, ontologically economic problems had ballooned to disproportionate levels. His initial approach to change was different to his predecessor; he took advice from field-experts and immediately set into motion economic Uskoreniye (acceleration). At this point, economic reform was indispensible as the collective agricultural sector lay in ruins with a lethargic 1.1 per cent output growth between 1981 and 1985, whilst industrial output growth fell from 8.5 per cent in 1966 to 3.7 per cent 1985.[40] Although Gorbachev could not permit himself mistakes, it is with Uskoreniye that the first decisional errors regarding the economy were committed and cost him much of his credibility. Under Abel Aganbegyans advisory, Gorbachev diverted Soviet funds to retool and refurbish the machinery industry, which was believed would accelerate scientific and technological progress. He supplemented this effort by reinforcing the centralisation of Soviet economy by creating super-ministries, that way planners could eliminate intermediate bureaucracies and concentrate on overall strategic planning.[41] Whereas these reforms did have some positive impacts, they were not far reaching enough to bring profound positive change to Soviet industrial production. Moreover, in the agricultural sector, Gorbachev initiated a crackdown on owners of private property in 1986, which led farmers to fear the government, and would disturb the success of future agricultural reforms. His error with Uskoreniye lay in the fact that he had aroused the population with his call for a complete overhaul of Soviet society, but in the economic realm at least, complete overhaul turned out for most part to be not much more than a minor lubrication job.[42] Realising his mistake, Gorbachev acquired the belief it was the economic system he had to change, and set out to do just that with his move towards Perestroika (Restructuring).

Gorbachev had at first tried simply to use the old machinery of government to reform. [] the main reason why this failed was that the old machinery [] were a very large part of the problem.[43]

Although the term Perestroika did exist prior to Gorbachevs tenure in office, it was he who remoulded it into a reform process that would attempt to totally restructure the archaic economic system. Unlike the first batch of economic reforms [] the second set seemed to reflect a turning away from the Stalinist economic system,[44] a move that startled the agricultural sector which had been subjected to repression the prior year. In 1987, Gorbachev legalised individual farming and the leasing of state land to farmers in an effort to enhance agronomic production. However, this reform was flawed due to the half-hearted nature of the endeavour, wherein farmers were allowed to buy land but it would remain state-owned. Therefore, due to Gorbachevs reluctance to fully privatise land, many prospective free farmers could see little point in developing farms that the state could snatch back at any time.[45] Adding to this social setback was the purely economic problem, since

without a large number of participants the private [] movements could never attain credibility. A large number of new sellers would produce a competitive environment that could hold prices down.[46]

Thus, due to Gorbachevs contradictory swift changes from agricultural repression to reluctant land leasing, his second agrarian reform failed.

Industrially, Gorbachev went even further in decisional miscalculations, without reverting his earlier move towards ultra-centralisation of the super-ministries, he embarked on a paradoxical semi-privatisation of markets. Gorbachevs 1987 Enterprise Law illustrates this as he attempted to transfer decision-making power from the centre to the enterprises themselves[47] through the election of factory managers by workers who would then decide what to produce and work autonomously. Adding to this, the 1988 Law on Cooperatives that legalized a wide range of small businesses[48] supplemented this move towards de-centralisation. Combined, it was anticipated that these reforms

would have introduced more motivation and market responsiveness [] in practice, it did nothing of the sort [] workers not surprisingly elected managers who offered an easy life and large bonuses.[49]

Moreover, the Enterprise Law contributed to the magnitude of the macro and monetary problems. [] [as] managers invariably opted to increase the share of expensive goods they produced,[50] which led to shortages of cheaper goods. Whilst, the law had reverse effects on workers, the blame lies with Gorbachev as no effort was put into the creation of a viable market infrastructure.

Without private banks from which to acquire investment capital, without a free market, [] without profit motive and the threat of closure or sacking, managers rarely had the incentive [] to change their ways.[51]

By going halfway in his efforts to create a market-oriented economy, Gorbachev destroyed his possibilities of success. The existing command-administrative economic system was weakened enough to be even less efficient, but not enough that market economics could begin to operate,[52] in effect, he had placed the economy in a nonsensical twilight zone. Consequently, the economy was plunged into a supply-side depression by 1991 since the availability of private and cooperative shops, which could charge higher prices, served to suck goods out of the state shops, which in turn caused labor unrest[53] and steady inflation. Here, Gorbachev began to feel the negative effects of his reforms, as mass disillusionment in his capability to lead the economy towards a superior model coupled with his emphasis on the abolition of repression and greater social freedom (Glasnost) tipped the USSR into a state of profound crisis.

The Success of Glasnost

Having understood Gorbachevs economical decisional errors with Perestroika, I will now set out to demonstrate how his simultaneous introduction of Glasnost in the social sector proved to be a fatal blow for the Soviet Union. Originally, Gorbachev set out to promote democratisation in 1987 as a complementary reform that would aid his economic ones, he saw Glasnost as a way to create nation of whistle-blowers who would work with him[54] against corruption. To the surprise of Soviet population, Gorbachev even encouraged socio-economic debates and allowed the formation of Neformaly, which were leisure organizations [and] up to a quarter were either lobby groups or were involved in issues [] which gave them an implicitly political function.[55] Gorbachev initiated this move at a time when the USSR was still searching for the correct reform process. Thus, the Neformaly movement was a way for him to strengthen the reform process without weakening the party by including the involvement of the public. But as Perestroika led to continuous setbacks, Gorbachev began to opt for more drastic measures with Glasnost, upholding his belief that the key lay in further democratisation. In November 1987, on the 70th anniversary of the October revolution, Gorbachev gave a speech purporting to Stalins crimes, which was followed by the resurgence of freedom of speech and gradual withdrawal of repression. Intellectually, politically and morally the speech would play a critical role in undermining the Stalinist system of coercion and empire.[56] At Gorbachevs behest, censorship was decreased and citizens could finally obtain truthful accounts regarding Soviet history and the outside world. However, this reform proved to be fairly detrimental as Soviet citizens were dismayed to find that their country actually lagged far behind the civilized countries. They were also taken aback by the flood of revelations about Soviet history.[57] While this did not trigger outbursts of unrest in amongst the population, it did have the cumulative impact of delegitimizing the Soviet regime in eyes of many Russians.[58] After his speech, Gorbachev continued his frenetic march towards democratisation with the astounding creation of a Congress of Peoples Deputies in 1989. Yet again, Gorbachev had found that the reform process necessitated CPSU support, however, conservatives at the heart of the party were continuously moving at cross-purpose to his reform efforts. Hence, by giving power to the people to elect deputies who would draft legislation, Gorbachev believed that he would be strengthening the government, [and] by creating this new Congress, he could gradually diminish the role of the Party regulars [conservatives].[59]

Instead of strengthening the government, Gorbachevs Glasnost of society pushed the USSR further along the path of social turmoil. In hindsight, it is possible to see that

the democracy Gorbachev had in mind was narrow in scope. [] Criticism [] would be disciplined [] and would serve to help, not hurt the reform process. [] His problems began when [] disappointment with his reforms led [] critics to disregard his notion of discipline.[60]

As soon as economic Perestroika failed to yield its promises, the proletariat began to speak out en masse, and instead of constructive openness, Gorbachev had created a Glasnost of criticism and disillusion. This was seen following the 1989 Congress, as social upheavals erupted when miners saw the politicians complain openly about grievances never aired before [61] and decided to do the same. In 1989, almost half the countrys coal miners struck,[62] followed by other episodes in 1991 when over 300,000 miners had gone out on strike.[63] Very quickly, Gorbachev also came to sourly regret his Neformaly initiative as workers, peasants, managers and even the military organized themselves in lobby groups, some of them asking the Kremlin to press forth with reforms and others asking to revert the whole reform process. Gorbachevs decisional error lay in his simultaneous initiation of Perestroika and Glasnost; as the latter met quick success whilst the economy remained in free-fall, society was plunged into a state of profound crisis.

Party Politics

Alongside his catastrophic reform of society and the economy, Gorbachev launched a restructuring of the CPSU, which he deemed essential to complement his economic reforms. In 1985, Gorbachev purged (discharged) elements of the CPSU nomenklatura, a term designating the key administrative government and party leaders.

Within a year, more than 20 to 30 % of the ranks of the Central Committee [] had been purged. Gorbachev expected that these purges would rouse the remaining members of the nomenklatura to support perestroika.[64]

This attack on the party served as an ultimatum to higher government and party officials who were less inclined on following Gorbachevs path of reform. Nevertheless, as economic and social turmoil ensued, Gorbachev went too far in his denunciation of the party, angering party members and causing amplified disillusionment within the proletariat. Examples of this are rife: behind the closed doors of the January 1987 Plenum of the Central Committee, Gorbachev [] accused the Party of resisting reform.[65] In 1988, Gorbachev also fashioned himself a scapegoat for economic failures: the Ligachev-led conservatives were strangling the reforms.[66] Up until 1988, this attack on the party nomenklatura did not have far-reaching repercussions, but as Gorbachev nurtured and strengthened the reformist faction of the CPSU, infighting between the conservatives and reformist began having two negative effects. The first one was widespread public loss of support for the party; this can be seen in the drop in Communist Party membership applications and rise in resignations. By 1988 the rate of membership growth had fallen to a minuscule 0.1 per cent, and then in 1989 membership actually fell, for the first time since 1954.[67] The other negative repercussion lay in how party infighting led to the inability of the CPSU to draft sensible legislation. This was due to Gorbachev continuously altering the faction he supported in order to prevent one from seizing power. Such a characteristic can be spotted in his legislative actions regarding the economy and social sector, which mirrored his incessant political shifts from the reformist faction to the conservative one. In 1990, Gorbachev opted for more de-centralisation and even greater autonomy in Soviet republics by creating the Presidential Council where heads of each republic were able to have a say in his decisions. However, he reversed course in 1991 with the creation of the Security Council where heads of republics now had to report to him directly, thus reasserting party control. Concerning the economy, Gorbachev acted similarly: as earlier explained, his first batch of reforms in 1986 stressed the need for centralisation with super-ministries, but he changed his mind the year after with his Cooperatives and Enterprise Laws and agricultural reforms. Gorbachev constantly

switched course [] [his] indecisiveness on the economy and the Soviet political system has generated more confusion than meaningful action. [] After a time, no one seemed to be complying with orders from the centre.[68]

In effect, it is possible to see here an overlapping of approaches since the way party infighting affected Gorbachevs reforms can be seen as a contingent factor that obstructed reform or a decisional error on Gorbachevs behalf for having reformed the party in such a manner.

Overall, this incoherence in his reform process can be seen as the result of his own decisional mistakes. Having succeeded in his Glasnost of society and the party, Gorbachev had allowed high expectation to flourish regarding his economic reforms, expectations that were gradually deceived. Amidst this social turmoil, economic downturn, party infighting and widespread disillusionment, Soviet republics began to move towards independence as the central command of the Kremlin progressively lost control and became evermore incoherent in its reforms.

The Death of the Union

As the Soviet Union descended into a state of socio-economic chaos, individual republics began to voice their plea to leave the union. This can be seen as having been triggered by the combination of three decisional errors on Gorbachevs behalf. The first one was his miscalculation of the outcome of Glasnost, as by 1990

all 15 republics began to issue calls for either economic sovereigntyor political independence. []Gorbachevs efforts to induce local groups to take initiative on their own were being implemented, but not always in the way he had anticipated.[69]

Originally, initiative had never been thought of as a topic that could lead to independence movements, instead Gorbachev had introduced this drive to stimulate workers and managers to find solutions that were akin to the problems felt in their factory or region. Adding to this mistake were Gorbachevs failed economic reforms with Perestroika, and as the Unions economic state degenerated, individual republics began to feel that independence was the key to their salvation. Gorbachevs

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History of the War on Drugs – About.com News & Issues

Posted: at 9:34 am

By Tom Head

At the turn of the 20th century, the drug market went mostly unregulated. Medical remedies, which often contained cocaine or heroin derivatives, were freely distributed without prescription--and without much consumer awareness of which drugs were potent and which were not. A caveat emptor attitude towards medical tonics could have meant the difference between life and death.

The Pure Food and Drug Act of 1906 targeted toxic drugs, and was expanded to address misleading drug labels in 1912. But the piece of legislation most relevant to the War on Drugs was the Harrison Tax Act of 1914, which restricted the sale of heroin and was quickly used to restrict the sale of cocaine as well.

And into this new national enforcement framework came the Marihuana Tax Act of 1937, which attempted to tax marijuana into oblivion Marijuana had not been shown to be dangerous, but the perception that it might be a "gateway drug" for heroin users--and its alleged popularity among Mexican-American immigrants--made it an easy target. More

Not that it did so alone. The Boggs Act of 1951 had already established mandatory minimum federal sentences for possession of marijuana, cocaine, and opiates, and a committee led by Senator Price Daniel (D-TX, shown left) called that the federal penalties be increased further, as they were with the Narcotic Control Act of 1956.

But it was Eisenhower's establishment of the U.S. Interdepartmental Committee on Narcotics, in 1954, in which a sitting president first literally called for a war on drugs.

So when the Nixon administration looked for ways to block the import of marijuana from Mexico, it took the advice of radical nativists: close the border. Operation Intercept imposed strict, punitive searches of traffic along on the U.S.-Mexican border in an effort to force Mexico to crack down on marijuana. The civil liberties implications of this policy are obvious, and it was an unmitigated foreign policy failure, but it demonstrated how far the Nixon administration was prepared to go.

Nixon also targeted the trendy, psychedelic image of illegal drugs, asking celebrities such as Elvis Presley (shown left) to help him send the message that drug abuse is unacceptable. Seven years later, Presley himself fell to drug abuse; toxicologists found as many as fourteen legally prescribed drugs, including narcotics, in his system at the time of his death.

The addition of the Drug Enforcement Administration (DEA) to the federal law enforcement apparatus in 1973 was a significant step in the direction of a criminal justice approach to drug enforcement. If the federal reforms of the Comprehensive Drug Abuse Prevention and Control Act of 1970 represented the formal declaration of the War on Drugs, the Drug Enforcement Administration became its foot soldiers.

It is not insignificant that the policy also came with political benefits. By portraying drugs as a threat to children, the administration was able to pursue more aggressive federal antidrug legislation.

Then along came crack, cocaine processed into little rocks at a price non-yuppies could afford. Newspapers printed breathless accounts of black urban "crack fiends" and the drug of rock stars suddenly grew more sinister to white middle America.

Congress and the Reagan administration responded with the Antidrug Act of 1986, which established a 100:1 ratio for mandatory minimums associated with cocaine. It would take 5,000 grams of powdered "yuppie" cocaine to land you in prison for a minimum 10 years--but only 50 grams of crack.

So when Senator Joe Biden's 1994 Omnibus Crime Bill included a provision allowing for the federal execution of drug kingpins, it indicated that the War on Drugs had ultimately reached such a level that drug-related offenses were regarded by the federal government as equivalent to, or worse than, murder and treason.

What is confusing is the issue of what happens when a state declares that a drug can be made legal with a prescription, and the federal government bullheadedly insists on targeting it as an illegal drug anyway. This happened in 1996 when California legalized marijuana for medical use. The Bush and Obama administrations have arrested California medical marijuana distributors anyway.

So far, the Obama administration's actual drug policy enforcement has not differed significantly from that of the Bush administration. But the War on Drugs has always been a rhetorical convention--you can't declare war on inanimate objects, social phenomena, moods, or abstractions--and it's a rhetorical convention that has determined the way our country views drug policy enforcement. Acknowledging that this is a policy initiative, not a war, is a good step.

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UCF Golden Rule UCF

Posted: at 9:32 am

The University of Central Florida is a community brought together by the tenets of the UCF Creed: Integrity, Scholarship, Community, Creativity, and Excellence. These are the values that guide our conduct, performance, and decisions. To be successful at UCF, there is an expectation that you embrace and promote these core values in everything you do as a sign of your membership in the UCF community.

Whether you are a new or continuing undergraduate, graduate or professional student at UCF, there are certain responsibilities that you must uphold as a member of our community. The Golden Rule is a compilation of policies and procedures from different university areas intended to define your rights and responsibilities as a student and provide you with a better understanding of your role as a member of the UCF community.

The Golden Rule is published once a year but can be revised at any time to reflect new and modified information deemed critical by the university. Changes will be communicated through online resources and other means, at which time the revisions will supersede published information.

The Office of Student Rights and Responsibilities (OSRR) within the Division of Student Development and Enrollment Services (SDES) is delegated the responsibility for reviewing, assembling, and communicating information included in The Golden Rule. Students are given the opportunity to influence the rules that they are expected to adhere through the Golden Rule Review Committee.

UCF values diversity and inclusion of all in our community. Accordingly, discrimination on the basis of race, sex, national origin, religion, age, disability, marital status, or veterans status is prohibited by federal and/or state law. It is our policy to treat all people with dignity and respect, without regard to race, creed, color, national origin, religion, sex, age, disability, marital status, sexual orientation, gender expression, gender identity, veteran status, or political opinions and affiliations.

For more information or further clarification, please contact OSRR at 407-823-4638, visit their website, http://osrr.sdes.ucf.edu for the most current version of The Golden Rule or email them at osrr@ucf.edu.

Go Knights! Charge ON!

Maribeth Ehasz, Ph.D.

For past years' Golden Rule Student Handbook, please see our archives page.

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UCF Golden Rule UCF

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Greece Economy: Population, Facts, GDP, Unemployment …

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Download PDF Quick Facts

The continuing lack of economic freedom compounds Greeces worsening competitiveness and political volatility. Bold policy actions are needed to restore fiscal sustainability, enhance labor market flexibility, and tackle systemic corruption.

Major fiscal weaknesses exposed by the debt and employment crisis have not been sufficiently addressed. Unemployment remains high, particularly among young people, and public unions and special interests stifle or delay adjustments to market conditions.

Greece joined NATO in 1952 and the European Union in 1981. It adopted the euro in 2002. Following elections in January 2015, the Coalition of the Radical Left (Syriza) party assumed power on a pledge to end austerity and renegotiate debt repayments. In August, the EU Commission, International Monetary Fund, and European Central Bank agreed to a $95 billion bailout package in exchange for more fiscal and economic reforms and additional austerity. It was the third bailout package in five years. Prime Minister Alexis Tsipras resigned in August after his support in parliament crumbled following his signing of the deal, but he was able to reestablish his coalition following snap elections in September. Greece remains mired in political and economic uncertainty, and its future in the eurozone is uncertain. The economy, which depends on shipping and tourism, fell back into recession in the first quarter of 2015 after a brief upswing. Unemployment is the highest in the eurozone.

Deeply rooted systemic cronyism and corruption, as well as the absence of a strong civil society, lie at the heart of the Greek debt crisis. Both public-sector and private-sector elites are able to plunder the country and their fellow citizens with impunity. Tax evasion is rampant. The judiciary is independent, but protection of property rights is not strongly enforced.

The top personal income tax rate has increased to 42 percent. The top corporate tax rate is 26 percent. The overall tax burden equals about 33.5 percent of GDP. Government spending remains at over 50 percent of GDP, chronic budget deficits continue, and public debt far exceeds the size of the economy. Fiscal stability is highly dependent on eurozone creditors, and structural adjustments have been marginal.

Efforts to enhance the business environment have been sporadic. The process for launching a company is fairly streamlined, but licensing requirements remain time-consuming. With high non-salary costs for employing a worker and rigid restrictions on work hours, the labor market remains stagnant. Resolution of the debt crisis will require privatization of heavily subsidized and loss-making state-owned enterprises.

EU members have a 1 percent average tariff rate. Trade agreements are currently being negotiated with countries that include the United States and Japan. Greece maintains non-tariff barriers to the provision of some professional services by non-EU providers. The financial systems overall stability has been severely undermined, and banking has been under increasing strain.

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Minerva – MicroWiki – Wikia

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The Republic of Minerva was one of the few modern attempts at creating a sovereign micronation on the reclaimed land of an artificial island in 1972.

Landing on Minerva, years after the confrontation.

More people walking on Minerva.

It is not known when the reefs were first discovered but had been marked on charts as "Nicholson's Shoal" since the late 1820s. Capt H. M. Denham of the HMS Herald surveyed the reefs in 1854 and renamed them after the Australian whaler Minerva which collided with South Minerva Reef on 9 September 1829.

In 1971, barges loaded with sand arrived from Australia, bringing the reef level above the water and allowing construction of a small tower and flag. The Republic of Minerva issued a declaration of independence on 19 January 1972, in letters to neighboring countries and even created their own currency. In February 1972, Morris C. Davis was elected as Provisional President of the Republic of Minerva.

The declaration of independence, however, was greeted with great suspicion by other countries in the area. A conference of the neighboring countries (Australia, New Zealand, Tonga, Fiji, Nauru, Samoa, and territory of Cook Islands) met on 24 February 1972 at which Tonga made a claim over the Minerva Reefs and the rest of the states recognized its claim.

On 15 June 1972, the following proclamation was published in a Tongan government gazette:

A Tongan expedition was sent to enforce the claim. Tongas claim was recognized by the South Pacific Forum in September 1972. Meanwhile, Provisional President Davis was fired by founder Michael Oliver and the project collapsed in confusion. Nevertheless, Minerva was referred to in O. T. Nelson's post-apocalyptic children's novel The Girl Who Owned a City, published in 1975, as an example of an invented utopia that the book's protagonists could try to emulate.

In 1982, a group of Americans led again by Morris C. Bud Davis tried to occupy the reefs, but were forced off by Tongan troops after three weeks.

In recent years several groups have allegedly sought to re-establish Minerva. No claimant group has to date made any attempt to take possession of the Minerva Reefs territory.

In November 2005, Fiji lodged a complaint with the International Seabed Authority concerning territorial claim over Minerva.

Tonga has lodged a counter claim. The Minerva "principality" group also claims to have lodged a counter claim.

Minerva Reefs

Area: North Reef diameter about 5.6km, South Reef diameter of about 4.8km. Cities: CapitalPort Victoria. Terrain: 2 island atollsmainly raised coral complexes on dormant volcanic islands.

Both Minerva Reefs are about 435km southwest of the Tongatapu Group. The atolls are on a common submarine platform from 549to1097meters (1800to3600feet) below the surface of the sea. Cardea is circular in shape and has a diameter of about 5.6km. There is a small island around the atoll, with a small entrance into the flat lagoon with a somewhat deep harbor. Aurora is parted into The East Reef and the West Reef, both circular with a diameter of about 4.8km. Around both atolls are two small sandy cays, vegetated by low scrub and some trees. Several iron towers and platforms are reported to stand near the atolls, along with an unused light tower on Aurora, erected by the Americans during World War II. Geologically the Minervan islands are of a limestone base formed from uplifted coral formations elevated by now-dormant volcanic activity.

The climate is basically subtropical with a distinct warm period (DecemberApril), during which the temperatures rise above 32C (90F), and a cooler period (MayNovember), with temperatures rarely rising above 27C (80F). The temperature increases from 23C to 27C (74F to 80F), and the annual rainfall is from 170 to 297 centimeters (67-117 in.) as one moves from Cardea in the south to the more northerly islands closer to the Equator. The mean daily humidity is 80%.

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Offshoring – Wikipedia, the free encyclopedia

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Offshoring is the relocation of a business process from one country to anothertypically an operational process, such as manufacturing, or supporting processes, such as accounting. Typically this refers to a company business, although state governments may also employ offshoring.[1] More recently, offshoring has been associated primarily with the outsourcing of technical and administrative services supporting domestic and global operations from outside the home country ("offshore outsourcing"), by means of internal (captive) or external (outsourcing) delivery models.[2]

India has emerged as a key offshoring destination over the past 15 years. The term is in use in several distinct but closely related ways. It is sometimes used broadly to include substitution of a service from any foreign source for a service formerly produced internally to the firm. In other cases, only imported services from subsidiaries or other closely related suppliers are included. A further complication is that intermediate goods, such as partially completed computers, are not consistently included in the scope of the term.[3]

Offshoring can be seen in the context of either production offshoring or services offshoring. After its accession to the World Trade Organization (WTO) in 2001, the People's Republic of China emerged as a prominent destination for production offshoring. Another focus area has been the software industry as part of global software development and developing global information systems. After technical progress in telecommunications improved the possibilities of trade in services, India became a country leading in this domain,[citation needed] though many parts of the world are now emerging as offshore destinations.

The economic logic is to reduce costs, sometimes called labor arbitrage, to improve corporate profitability. Jobs are added in the destination country providing the goods or services (generally a lower-cost labor country), but are subtracted in the higher-cost labor country. The increased safety net costs of the unemployed may be absorbed by the government (taxpayers) in the high-cost country or by the company doing the offshoring. Europe experienced less offshoring than the United States due to policies that applied more costs to corporations and cultural barriers.[4]

Offshoring is defined as the movement of a business process done at a company in one country to the same or another company in another, different country. Almost always work is moved because of a lower cost of operations in the new location. More recently, offshoring drivers also include access to qualified personnel abroad, in particular in technical professions, and increasing speed to market.[2] Offshoring is sometimes contrasted with outsourcing or offshore outsourcing. Outsourcing is the movement of internal business processes to an external organizational unit. Outsourcing refers to the process by which an organization gives part of its work to another firm / organization and makes it responsible for most of the applications as well as the design of the enterprise business process. This process is done under restrictions and strategies in order to establish consistency with the offshore outsourcing organizations. Many companies nowadays outsource various professional areas in the company such as e-mail services, payroll and call center. These jobs are being handled by other organizations that specialize in each sector allowing the offshoring company to focus more on other business concerns . However, subcontracting in the same country would be outsourcing, but not offshoring. A company moving an internal business unit from one country to another would be offshoring or physical restructuring, but not outsourcing. A company subcontracting a business unit to a different company in another country would be both outsourcing and offshoring.

Related terms include nearshoring, which implies relocation of business processes to (typically) lower cost foreign locations, but in close geographical proximity (e.g., shifting United States-based business processes to Canada/Latin America); inshoring, which means picking services within a country; and bestshoring or rightshoring, picking the "best shore" based on various criteria. Business process outsourcing (BPO) refers to outsourcing arrangements when entire business functions (such as Finance & Accounting, Customer Service, etc.) are outsourced. More specific terms can be found in the field of software development - for example Global Information System as a class of systems being developed for / by globally distributed teams.

A further term sometimes associated with offshoring is bodyshopping which is the practice of using offshored resources and personnel to do small disaggregated tasks within a business environment, without any broader intention to offshore an entire business function.

Production offshoring, also known as physical restructuring, of established products involves relocation of physical manufacturing processes to a lower-cost destination. Examples of production offshoring include the manufacture of electronic components in Costa Rica, production of apparel, toys, and consumer goods in China, Vietnam etc.

Product design, research and the development process that leads to new products, are relatively difficult to offshore. This is because research and development, in order to improve products and create new reference designs, require a skill set that is harder to obtain in regions with cheap labor. For this reason, in many cases only the manufacturing will be offshored by a company wishing to reduce costs.

However, there is a relationship between offshoring and patent-system strength. This is because companies under a strong patent system are not afraid to move work offshore because their work will remain their property. Conversely, companies in countries with weak patent systems have an increased fear of intellectual property theft from foreign vendors or workers, and, therefore, have less offshoring.

A major incentive for physical restructuring arrived when the North American Free Trade Agreement (NAFTA) made it easier for manufacturers to shift production facilities from the US to Mexico. This trend later shifted to China, which offered cheap prices through very low wage rates, few workers' rights laws, a fixed currency pegged to the US dollar, (currently fixed to a basket of economies) cheap loans, cheap land, and factories for new companies, few environmental regulations, and huge economies of scale based on cities with populations over a million workers dedicated to producing a single kind of product. However, many companies are reluctant to move high value-added production of leading-edge products to China because of lax enforcement of intellectual property laws.[5] CAFTA has increased the velocity at which physical restructuring is occurring.

The growth of IT-enabled services offshoring is linked to the availability of large amounts of reliable and affordable communication infrastructure following the telecommunication and Internet expansion of the late 1990s. This was seen all the way up to the year 2000. Coupled with the digitization of many services, it was possible to shift the actual production location of services to low-cost countries in a manner theoretically transparent to end-users. Services include administrative services, such as finance and accounting, HR, and legal; call centers; marketing and sales services; IT infrastructure; application development; and knowledge services, including engineering support, product design, research and development, and analytics. General criteria for choosing IT outsourcing development partner commonly include: communication and language proficiency (both oral and written), previous work experience in client's industry, expertise in defined technologies needed, cost-effectiveness of offshore web development services, clients that are similar in size to the client's company, company longevity, company time zone.[6]

India first benefited from the offshoring trend, as it has a large pool of English speaking people and technically proficient manpower.[7] India's offshoring industry took root in low-end IT functions in the early 1990s and has since moved to back-office processes such as call centers and transaction processing. This spawned the neologism Bangalored, used to indicate a layoff, often systemic, and usually resulting from corporate outsourcing to lower wage economies derived from Bangalore in India, where some of the first outsource centers were located.[8]

Currently, India's low-cost labor has made it an offshoring destination for global firms like HP, IBM, Accenture, Intel, AMD, Microsoft, Oracle Corporation, Cisco, SAP, and BEA[disambiguation needed].

Because of inflation, high domestic interest rates, robust economic growth and increased IT offshoring, the Indian IT sector has witnessed 10 - 15% wage growth in the 21st century. Consequently, Indian's operations and firms are concerned that they are becoming too expensive in comparison with competition from the other offshoring destinations. To maintain high growth rates, attempts have been made to grow up the value chain and diversify to other high-end work in addition to software and hardware engineering. These jobs include research and development, equity analysis, tax-return processing, radiological analysis, medical transcription, and more.

The choice of offshoring destination is often made according to cultural concerns. Japanese companies are starting to outsource to China, where large numbers of Japanese speakers can be found particularly in the city of Dalian, which was Japanese-occupied Chinese territory for decades (this is discussed in the book The World is Flat). German companies tend to outsource to Eastern European countries, such as Ukraine, where the most number of IT professionals in CEE work (90000 IT specialists in 2016),[9]Poland and Romania, where proficiency in German is common.[10] French companies outsource to North Africa for similar reasons. For Australian IT companies, Indonesia is one of the major choice of offshoring destination. Near-shore location, common time zone and adequate IT work force are the reasons for offshoring IT services to Indonesia.

Other offshoring destinations include Mexico, Central and South America, the Philippines, South Africa and Eastern European countries.

The Central America Free Trade Agreement (CAFTA) made nearshoring more attractive between the Central American countries of Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua, and the Dominican Republic and the US.

Once companies are comfortable with services offerings and started realizing the cost savings, many high-tech product companies, including some in Silicon Valley, started offshoring innovation work to countries like Belarus, South Africa, India, China, Mexico, Russia and Ukraine. Accessing the talent pools in these countries has the potential to cut costs or even shorten product lifecycles. Developing countries like India are also involved in this practice.

When offshoring knowledge work, firms heavily rely on the availability of technical personnel at offshore locations. In order to secure access to talent, Western firms often establish collaborative relationships with technical universities abroad and thereby customize university programs to serve their particular needs. Examples include universities in Shanghai, such as Tong-Ji University, where German firms and scholars co-sponsor labs, courses, and provide internships. Similar examples of collaborative arrangements can be found in Eastern Europe, e.g. Romania.[10] Additionally, EU companies looking for IT innovation often setup collaboration with universities in countries such as Belarus and Ukraine, which have a high percentage of ICT graduates and overall a very skilled IT labor.[11]

"Re-shoring", also known as "backshoring"[12] or "inshoring"[13] is offshoring that has been brought back onshore.[14]

John Urry (distinguished professor of sociology at Lancaster University) argues that the concealment of income, the avoidance of taxation and eluding legislation relating to work, finance, pleasure, waste, energy and security may be becoming a serious concern for democratic governments and ordinary citizens who may be adversely affected by unregulated, offshore activities. Further, the rising costs of transportation could lead to production nearer the point of consumption becoming more economically viable, particularly as new technologies such as additive manufacturing mature [15]

Offshoring is often enabled by the transfer of valuable information to the offshore site. Such information and training enables the remote workers to produce results of comparable value previously produced by internal employees. When such transfer includes protected materials, as confidential documents and trade secrets, protected by non-disclosure agreements, then intellectual property has been transferred or exported. The documentation and valuation of such exports is quite difficult, but should be considered since it comprises items that may be regulated or taxable.

Offshoring has been a controversial issue spurring heated debates among economists, some of which overlap those related to the topic of free trade. It is seen as benefiting both the origin and destination country through free trade, providing jobs to the destination country and lower cost of goods and services to the origin country. This makes both sides see increased gross domestic product (GDP). And the total number of jobs increases in both countries since those workers in the origin country that lost their job can move to higher-value jobs in which their country has a comparative advantage.

On the other hand, job losses and wage erosion in developed countries have sparked opposition to offshoring. Experts argue that the quality of any new jobs in developed countries are less than the jobs lost and offer lower pay. Economists against offshoring charge that currency manipulation by governments and their central banks causes the difference in labor cost creating an illusion of comparative advantage. Further, they point out that even more educated highly trained workers with higher-value jobs such as software engineers, accountants, radiologists, and journalists in the developed world have been displaced by highly educated and cheaper workers from India and China. On May 1, 2002, Economist and former Ambassador Ernest H. Preeg testified before the Senate committee on Banking, Housing, and Urban Affairs that China, for instance, pegs its currency to the dollar at a sub-par value in violation of Article IV of the International Monetary Fund Articles of Agreement which state that no nation shall manipulate its currency to gain a market advantage.[16] Traditionally "safe" developed world jobs in R&D and the Science, Technology, Engineering, and Mathematics (STEM) fields are now perceived to be endangered in these countries as higher proportions of workers are trained for these fields in developing nations. Economists such as Paul Craig Roberts claim that those economists who promote offshoring misunderstand the difference between comparative advantage and absolute advantage.

The Economist reported in January 2013 that: "High levels of unemployment in Western countries after the 2007-2008 financial crisis have made the public in many countries so hostile towards offshoring that many companies are now reluctant to engage in it."[17] Economist Paul Krugman wrote in 2007 that while free trade among high-wage countries is viewed as win-win, free trade with low-wage countries is win-lose for many employees who find their jobs offshored or with stagnating wages.[18] Two estimates of the impact of offshoring on U.S. jobs were between 150,000 and 300,000 per year from 2004-2015. This represents 10-15% of U.S. job creation.[19] U.S. opinion polls indicate that between 76-95% of Americans surveyed agreed that "outsourcing of production and manufacturing work to foreign countries is a reason the U.S. economy is struggling and more people aren't being hired."[20][21]

The increased safety net costs of the unemployed may be absorbed by the government (taxpayers) in the high-cost country or by the company doing the offshoring. Europe experienced less offshoring than the U.S. due to policies that applied more costs to corporations and cultural barriers.[4]

Japanese companies often exploits the foreign labors, particularly Chinese and Vietnamese, by violating the Employment Security Act, and Labor Standard Act set by ministry of health and labors in Japan using the name of offshoring.

Article 44 of Employment Security Act in Japan implicitly bans the domestic/foreign workers being supplied by unauthorized companies regardless of their operating locations. Law will apply if at least one party of suppliers, clients, labors reside in Japan, and if the labors are the integral part of the chain of command by the client company, or the supplier.

No person shall carry out a labor supply business or have workers supplied by a person who carries out a labor supply business work under his/her own directions or orders, except in cases provided for in the following Article.

Employment Security Act

Those deemed to violate will be punished with

A person who falls under any of the following items shall be punished by imprisonment with work for not more than one year or a fine of not more than one million yen

Employment Security Act states, Article 64

as well as the punishment defined by the article 6 of Labor Standards Act in Japan,

Unless permitted by act, no person shall obtain profit by intervening, as a business, in the employment of other

Victims can lodge a criminal complaint against the CEO of the suppliers and clients in the Labor Standards Inspection Office (only applicable to Labor Standards Act) or Public Prosecutor's Office of the respective company location. Due to the risk of the CEO's arrest, Japanese company accustoms to the private settlement with financial package in the range between 20 and 100 million JPY (200,000 - million USD).

With the offshoring of call-center type applications, debate has also surfaced that this practice does serious damage to the quality of customer service and technical support that customers receive from companies who do it. Many companies have caught much public ire for their decisions to use foreign labor for customer service and technical support, mostly because of the apparent language barrier that it creates. While some nations have a high level of younger, skilled workers who are capable of speaking English as one of their native languages, their English skills have caused debate in North America and Europe.[citation needed]

Criticisms of outsourcing from much of the American public have been a response to what they view as very poor customer service and technical support being provided by overseas workers attempting to communicate with Americans.

Some claim that companies lose control and visibility across their extended supply chain under outsourcing, creating increased risks. A 2005 quantitative survey of 121 electronics industry participants by Industry Directions Inc and the Electronics Supply Chain Association (ESCA) found that 69% of respondents said they had less control over at least 5 of their key supply chain processes since the outsourced model took hold, while 66% of providers felt their aggregate risk with customers was high or very high.[citation needed] 36% of providers responded that they felt an increased risk of uncertainty compared to their uncertainty risk before the rise to prominence of the outsourced model.[citation needed] 62% of respondents described as "problematic" at least two core trading partner management practices, which included performance management and simple agreement on results.[citation needed] 40% of all respondents encountered resistance to sharing risk in outsourced partnership agreements, according to the research.[citation needed]

The transfer of knowledge outside a country may create competitors to the original companies themselves. Chinese manufacturers are already selling their goods directly to their overseas customers, without going through their previous domestic intermediaries that originally contracted their services. In the 1990s and 2000s, American automakers increasingly turned to China to create parts for their vehicles. By 2006, China leveraged this know-how and announced that they will begin competition with American automakers in their home market by selling fully Chinese automobiles directly to Americans. When a company moves the production of goods and services to another country, the investment that companies would otherwise make in the domestic market is transferred to the foreign market. Corporate money spent on factories, training, and taxes, which would otherwise be spent in the market of the company is then spent in the foreign market. As production increases in the foreign market, qualified and experienced domestic workers leave or are forced out of their jobs, often permanently leaving the industry. At some point, dramatically fewer domestic workers are left who are qualified to perform the work. This makes the domestic market dependent on the foreign market for those goods and services, thereby strategically weakening the "hollowed-out" domestic country. In effect, offshoring creates and strengthens the competitive industries of the foreign country while strategically weakening the domestic country.[dubious discuss]

However, employment data has cast doubt on this claim. For example, IT employment in the United States has recently reached pre-2001 levels[23][24] and has been rising since. The number of jobs lost to offshoring is less than 1 percent of the total US labor market.[25] According to a study by the Heritage foundation, outsourcing represents a very small proportion of jobs lost in the US. The total number of jobs lost to offshoring, both manufacturing and technical represent only 4 percent of the total jobs lost in the US. Major reasons for cutting jobs are from contract completion and downsizing.[26] Some economists and commentators claim that the offshoring phenomenon is way overblown.[26]

One solution often offered for domestic workers displaced by offshoring is retraining to new jobs. Some displaced workers are highly educated and possess graduate qualifications. Retraining to their current level in another field may not be an option because of the years of study and cost of education involved. Anecdotal evidence also suggests they would be rejected for being overqualified.

According to classical economics, the three factors of production are land, labor, and capital. Offshoring relies heavily on the mobility of two of these factors. That is, how offshoring affects economies depends on how easily capital and labor can be repurposed. Land, as a factor of production, is generally seen to have little or no mobility potential.

The effects of capital mobility on offshoring have been widely discussed. In microeconomics, a corporation must be able to spend working capital to afford the initial costs of offshoring. If the state heavily regulates how a corporation can spend its working capital, it will not be able to offshore its operations. For the same reason the macroeconomy must be free for offshoring to succeed. Generally, those who favor offshoring support capital mobility, and those who oppose offshoring call for greater regulation.

Labor mobility also plays a major role, and it is hotly debated. When computers and the Internet made work electronically portable, the forces of free market resulted in a global mobility of work in the services industry. Most theories that argue offshoring eventually benefits domestic workers assume that those workers will be able to obtain new jobs, even if they have to obtain employment by downpricing themselves back into the labor market (by accepting lower salaries) or by retraining themselves in a new field. Foreign workers benefit from new jobs and higher wages when the work moves to them.

In the developed world, moving manufacturing jobs out of the country dates to at least the 1960s[27] while moving knowledge service jobs offshore dates to the 1970s [28] and has continued since then. It was characterized primarily by the transferring of factories from the developed to the developing world. This offshoring and closing of factories has caused a structural change in the developed world from an industrial to a post-industrial service society.

During the 20th century, the decreasing costs of transportation and communication crossed with great disparities on pay rates made increased offshoring from wealthier countries to less wealthy countries financially feasible for many companies. Further, the growth of the Internet, particularly fiber-optic intercontinental long haul capacity, and the World Wide Web reduced "transportation" costs for many kinds of information work to near zero.[29]

With the development of the Internet, many new categories of work such as call centres, computer programming, reading medical data such as X-rays and magnetic resonance imaging, medical transcription, income tax preparation, and title searching are being offshored.

Before the 1990s, Ireland was one of the poorest countries in the EU. Because of Ireland's relatively low corporate tax rates, US companies began offshoring of software, electronic, and pharmaceutical intellectual property to Ireland for export. This helped create a high-tech "boom" and which led to Ireland becoming one of the richest EU countries.[29]

In 1994 the North American Free Trade Agreement (NAFTA) went into effect. As concerns are widespread about uneven bargaining powers, and risks and benefits, negotiations are often difficult, such that the plan to create free trade areas (such as Free Trade Area of the Americas) has not yet been successful. In 2005, offshoring of skilled work, also referred to as knowledge work, dramatically increased from the US, which fed the growing worries about threats of job loss.[29]

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Offshoring - Wikipedia, the free encyclopedia

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