Key point: As prescription volume precipitously drops, the overdose rate continues apace.

A new study reported in the November 1, 2019Annals of Emergency Medicinepours morecold water on the false but persistent narrative that the opioid overdose crisis wascaused by doctors prescribing opioids to patients in pain.

This prospective cohort study by researchers in the Department of Emergency Medicine at Albert Einstein College of Medicine followed 484 opioid nave patients prescribed opioids for acute pain upon release from the emergency department during a six month period. The statewide prescription drug monitoring program was employed in addition to regular follow up telephone interviews. One percent (five patients) met the criteria for persistent opioid use by the end of the follow up period. Four of the five patients still had moderate or severe pain in the affected body part six months after release from the emergency department.

The study comes after a much larger retrospective cohort studyreported in theBMJof more than 568,000 opioid nave patients prescribed opioids for acute postoperative pain between 2008 and 2016. Investigators found a totalmisuserate of 0.6 percent.The researchersdefined misuse as follows:

The primary outcome was an ICD-9 (international classification of diseases, ninth revision) diagnosis code of opioid dependence, abuse, or overdoseOpioid misuse was defined as the presence of at least one of these ICD codes after discharge and encompasses a composite of a wide range of forms of misuse. We included only diagnosis codes related specifically to prescription opioids.

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