Gennady Stolyarov II

The Transhumanist Party is pleased to announce the revitalization of an ongoing official activism project one that all members, irrespective of geographical location, can easily join. This is a project that utilizes our favored approach of direct, individually attainable action toward the creation of a brighter future.

You can personally help advance the fight against a multitude of diseases such as Alzheimers Disease, Parkinsons Disease, and many cancers.

The Longevity Meme Folding@home team a group of volunteers who donate their computing power to perform protein-folding simulations that could one day result in cures for major diseases and the lengthening of human lifespans has been operating for years, contributing otherwise idle computer resources to actual meaningful biological research.

To take part in this effort, just download the client for the Folding@home project at http://folding.stanford.edu/. Then join The Longevity Meme team here, and your computer will do the rest over time. I have personally been engaged in this effort for over six years.

If you would like a digital reward for contributing to this project, I am able to give five levels of digital Open Badges via Credly. Here is a page describing the various tiers of badges.Once you have reached the requisite number of Folding@home points to claim each badge, just contact me via e-mailhere with a message that includes your user name and an e-mail address.

The Transhumanist Party supports Lifespan.io and CellAge in their work towards groundbreaking scientific life-extension research. Finding a way to repair age-related damage to senescent cells would be a fundamental breakthrough for transhumanism, and we offer our best wishes and support for those striving towards these new technologies.

From Lifespan.io and CellAge:

Our society has never aged more rapidly one of the most visible symptoms of the changing demographics is the exponential increase in the incidence of age-related diseases, including cancer, cardiovascular diseases and osteoarthritis. Not only does aging have a negative effect on the quality of life among the elderly but it also causes a significant financial strain on both private and public sectors. As the proportion of older people is increasing so is health care spending. According to a WHO analysis, the annual number of new cancer cases is projected to rise to 17 million by 2020, and reach 27 million by 2030. Similar trends are clearly visible in other age-related diseases such as cardiovascular disease. Few effective treatments addressing these challenges are currently available and most of them focus on a single disease rather than adopting a more holistic approach to aging.

Recently a new approach which has the potential of significantly alleviating these problems has been validated by a number of in vivo and in vitro studies. It has been demonstrated that senescent cells (cells which have ceased to replicate due to stress or replicative capacity exhaustion) are linked to many age-related diseases. Furthermore, removing senescent cells from mice has been recently shown to drastically increase mouse healthspan (a period of life free of serious diseases).

Here at CellAge we are working hard to help translate these findings into humans!

CellAge, together with a leading synthetic biology partner, Synpromics, are poised to develop a technology allowing for the identification and removal of harmful senescent cells. Our breakthrough technology will benefit both the scientific community and the general public.

In short, CellAge is going to develop synthetic promoters which are specific to senescent cells, as promoters that are currently being used to track senescent cells are simply not good enough to be used in therapies. The most prominently used p16 gene promoter has a number of limitations, for example. First, it is involved in cell cycle regulation, which poses a danger in targeting cells which are not diving but not senescent either, such as quiescent stem cells. Second, organism-wide administration of gene therapy might at present be too dangerous. This means senescent cells only in specific organs might need to be targeted and p16 promoter does not provide this level of specificity. Third, the p16 promoter is not active in all senescent cells. Thus, after therapies utilizing this promoter, a proportion of senescent cells would still remain. Moreover, the p16 promoter is relatively large (2.1kb), making it difficult to incorporate in present gene therapy vehicles. Lastly, to achieve the intended therapeutic effect the strength of p16 promoter to drive therapeutic effect might not be high enough.

CellAge will be constructing a synthetic promoter which has a potential to overcome all of the mentioned limitations. A number of gene therapy companies, including uniQure, AGTC and Avalanche Biotech have successfully targeted other types of cells using this technology. With your help, we will be able to use same technology to develop tools and therapies for accurate senescent cell targeting.

Gennady Stolyarov II

The United Nations Public Administration Network (UNPAN) has taken notice of the Transhumanist Party on its website, where it republished an article originally written by Dylan Love of NBC News. This November 18, 2016, article is titled The Next Global Race Aims to Perfect Artificial Intelligence and highlights Zoltan Istvans discussion of possibilities for the future of artificial intelligence, as well as concerns about geopolitical competition over AI development.

An excerpt from the article shows how the Transhumanist Party has contributed to discussion of this issue in a manner that the UN has deemed noteworthy:

Zoltan Istvan is founder of the Transhumanist Party, a legally recognized and PR-minded political effort that calls attention to what tomorrows mainstreaming of todays rapidly developing technology could mean for human life.

Istvan campaigned for the U.S. presidency in 2016 on the platform of harnessing existing technologies to maximize both the quality and duration of ones life. Though his theoretical thinking may seem to border on the fantastic, Istvan has enough street cred at the intersection of politics and technology that he has consulted with the U.S. Navy on the geopolitical implications of artificial intelligence. He readily identifies it as nothing less than a national security concern.

The Transhumanist Party encourages a diversity of perspectives from its members regarding the future potential, promise, and risks of artificial intelligence. In accord with its stepwise shift to a more participatory and member-driven governance model, the Transhumanist Party will soon be hosting discussion panels on a wide array of emerging technologies and their political and societal implications. Artificial intelligence will be among the first areas of technology discussed.

Gennady Stolyarov II

The following is the draft sample ballot generated thus far as a compilation of the suggestions provided during the 30-day exposure period for the Transhumanist Bill of Rights. The exposure period will continue until 12:01 a.m. U.S. Pacific Time on December 25, 2016,and comments will continue to be solicited until that time, with any further reasonable suggestions incorporated into the draft sample ballot until the end of the exposure period.

The draft sample ballot is a work in progress and will be revised on this page as further input is received. The purpose of releasing the sample ballot at this time is to provide insight into the structure of the voting and the options that have already been generated, so as to enable any interested members of the Transhumanist Party to read and understand the available options and propose further refinements and alternatives.

After the exposure period, a 7-day electronic voting period will occur from 12:01 a.m. U.S. Pacific Time on December 25, 2016, to 12:01 a.m. U.S. Pacific Time on January 1, 2017. Instructions for electronic voting will be sent to members of the U.S. Transhumanist Party via e-mail. All individuals who are members of the U.S. Transhumanist Partyas of the end of the exposure periodand who have expressed agreement with its threeCore Idealswill be eligible to vote thereafter.

Electronic voting will be conducted by a ranked-preference method on individual articles where more options are possible than would be accommodated by a simple Yes or No vote. Members should keep in mind that the ranked-preference method eliminates the incentives for strategic voting so members are encouraged to vote for the options that reflect their individual preferences as closely as possible, without regard for how other members might vote.

NOTE: The titles of the questions and potential Articles are descriptive and informational only and will not appear in the final adopted Transhumanist Bill of Rights. They are intended as concise guides to the subject matter of the questions and potential Articles. Likewise, the numbers or letters assigned to Articles within this ballot will not reflect the numbering in the final adopted Transhumanist Bill of Rights, which will depend on which Articles are selected by the membership. For purposes of convenient distinction, the original Articles developed by Zoltan Istvan are assigned Arabic numerals (1 through 6), while the new Articles proposed by the membership are assigned Latin letters (A through R, thus far).

NOTE II:The inclusion of any proposals on this ballot doesnot indicate any manner of endorsement for those proposals by the U.S. Transhumanist Party at this time except to place those proposals before the members to determine the will of the members with regard to whether or not the Transhumanist Bill of Rights should incorporate any given proposal.

Rank-order the Preamble Options that you support. Choose 1 for your most highly favored option, 2 for your second-most highly favored option, etc. If you choose Abstain, then do not rank-order any options, as you will be considered to have skipped this question.

Preamble Option 1 [Original Text by Zoltan Istvan]. Whereas science and technology are now radically changing human beings and may also create future forms of advanced sapient and sentient life, transhumanists establish this TRANSHUMANIST BILL OF RIGHTS to help guide and enact sensible policies in the pursuit of life, liberty, security of person, and happiness.

Preamble Option 2. Transhumanist evolution is underway and establishes life principles that allow a sentient entity to alter, augment, and perform self-improvement efforts utilizing science and technology to achieve supreme intellectual, physical, and psychological capacities. This TRANSHUMANIST BILL OF RIGHTS extends sentient rights to enhanced neo-humans, cybernetic, transgenic, anthropomorphic, and avatar beings. The TRANSHUMANIST BILL OF RIGHTS provides a sentient entity the right to procreate, clone, and form, the right to expand and extend life beyond biological fundamental boundaries, and to live life without illness, aging, and catastrophic loss of self in pursuit of immortality. This TRANSHUMANIST BILL OF RIGHTS provides principles for intellectual and inclusive policies for all sentient entities in pursuit of life, liberty, eternal existence, and freedom to be different.

The TRANSHUMANIST BILL OF RIGHTS is not static. As the collective of sentient entities continues to unravel the mysteries of the Universe and discover more facts, the TRANSHUMANIST BILL OF RIGHTS will change. We (sentient entities) must be malleable, inclusive, and understanding in thought and spirit at the same pace as society evolves. We must continue to aspire, gain knowledge, and improve life.

Preamble Option 3. Transhumanist evolution is underway and establishes life principles that allow a sentient entity to alter, augment, and perform self-improvement efforts utilizing science and technology to achieve supreme intellectual, physical, and psychological capacities; to provide a sentient entity the rights to procreate, clone, and adapt form; to expand and extend life beyond present-day boundaries; and to live life without illness and loss of self in pursuit of immortality. We organize to provide principles for intellectual and inclusive policies for all sentient entities in pursuit of life, liberty, and eternal existence. This TRANSHUMANIST BILL OF RIGHTS extends sentient rights to all humans, cyborgs, transgenic, anthropomorphic, avatar, and yet-to-be-identified beings as defined herein.

The TRANSHUMANIST BILL OF RIGHTS is not static. As the collective of sentient entities continues to unravel the mysteries of the Universe and discover more facts, the TRANSHUMANIST BILL OF RIGHTS will change. We (sentient entities) must be malleable, inclusive, and understanding in thought and spirit at the same pace as society evolves. We must continue to aspire, gain knowledge, and improve life.

Preamble Option 4 [Usable if Option II(e) or Option II(f) below is adopted as well]. Transhumanist evolution is underway and establishes life principles that allow a sentient entity to alter, augment, and perform self-improvement efforts utilizing science and technology to achieve greaterintellectual, physical, and psychological capacities. This TRANSHUMANIST BILL OF RIGHTS extends sentient rights to enhanced neo-humans, cybernetic, transgenic, anthropomorphic, and avatar beings as well as any other being that demonstrates meta-cognition and self-directed awareness, which is capable of simultaneously modeling itself and its relation to the external reality, and whose cognitive processes can be described as lucid (characterized by continuous integration of information at Level 5 or a higher level as defined herein). The TRANSHUMANIST BILL OF RIGHTS provides a sentient entity the right to procreate, clone, and form, the right to expand and extend life beyond unenhanced biological fundamental boundaries, and to live life without illness, aging, and catastrophic loss of self in pursuit of immortality. This TRANSHUMANIST BILL OF RIGHTS provides principles for intellectual and inclusive policies for all sentient entities in pursuit of life, liberty, eternal existence, and self-actualization.

The TRANSHUMANIST BILL OF RIGHTS is not static. As the collective of sentient entities continues to unravel the mysteries of the Universe and discover more facts, the TRANSHUMANIST BILL OF RIGHTS will change. We (sentient entities) must be malleable, inclusive, and understanding in thought and spirit at the same pace as society evolves as we push mankind forward. We must continue to aspire, gain knowledge, and improve life.

Abstain.

Version 1 of the Transhumanist Bill of Rights uses the enumeration of human beings, sentient artificial intelligences, cyborgs, and other advanced sapient life forms in each Article to refer to the entities encompassed by that Article. It has been suggested, instead, that a more concise term might be used in the Preamble to encompass all of the above-enumerated entities and perhaps others.

Such phrasing would be of the following form:

As used in this TRANSHUMANIST BILL OF RIGHTS, the term [CHOSEN TERM] includes human beings, sentient artificial intelligences, cyborgs, and other advanced sapient life forms.

Shall the Preamble be amended to include the above-quoted statement and, in all Articles, replace the enumeration of human beings, sentient artificial intelligences, cyborgs, and other advanced sapient life forms withthe term selected as [CHOSEN TERM]?

Rank-order your preference for whether to use such a more concise all-encompassing term and, if so, what that term might be. Choose 1 for your most highly favored option, 2 for your second-most highly favored option, etc. If you choose Abstain, then do not rank-order any options, as you will be considered to have skipped this question.

Option II(a). Keep the enumeration of human beings, sentient artificial intelligences, cyborgs, and other advanced sapient life forms in each article.

Option II(b). Use thought-capable individuals as the chosen term.

Option II(c). Use advanced sapient life forms as the chosen term and remove that term from the longer descriptive listing. If this option is chosen, advanced sapient life forms will be defined to mean human beings, sentient artificial intelligences, cyborgs, and other beings of comparable cognitive capability.

Option II(d). Use sentient entities as the chosen term.

Option II(e).Use sentient entities as the chosen term, with a hierarchical definition of sentience as described below:

Sentient entities are defined by information-processing capacity such that this term should not apply to non-self-aware lifeforms, like plants and slime molds. Biological processing substrates are referred to as using an analogue intelligence, whereas purely electronic processing substrates are referred to as digital intelligence (instead of sentient artificial intelligences), and processing substrates that utilize quantum effects would be considered quantum intelligence.

Sentience is ranked as Level 5 information integration according to the following criteria:

Option II(f).Use sentient entities as the chosen term, with a further clarification that sentient entities include all entities exhibiting Level 5 information integration, or lucidity meaning that any such entity is meta-aware aware of ones own awareness, aware of abstractions, aware of ones self, and therefore able to actively analyze each of these phenomena.

Abstain.

Shall the definition of beings to whom the Transhumanist Bill of Rights applies include a specific mention of Gods and Archangels? Select one of the following options?

Yes.

No.

Abstain.

Shall the definition of beings to whom the Transhumanist Bill of Rights applies include a specific mention of genetically modified humans? Select one of the following options.

Yes.

No.

Abstain.

Shall the definition of beings to whom the Transhumanist Bill of Rights applies include a specific mention of intellectually enhanced, previously non-sapient animals? Select one of the following options.

Yes.

No.

Abstain.

Shall the definition of beings to whom the Transhumanist Bill of Rights applies include a specific mention of any species of plant or animal which has been enhanced to possess the capacity for intelligent thought? Select one of the following options.

Yes.

No.

Abstain.

Rank-order the Article 1 Options that you support. Choose 1 for your most highly favored option, 2 for your second-most highly favored option, etc. You may include the option for No Article of this sort in your rank-ordering, and it does not need to be your most favored option if you do so. (For instance, some voters might favor some options but think that no language is preferable to some of the other options.)

If you choose Abstain, then do not rank-order any options, as you will be considered to have skipped this question.

Option 1-1 [Original Text by Zoltan Istvan]. Human beings, sentient artificial intelligences, cyborgs, and other advanced sapient life forms are entitled to universal rights of ending involuntary suffering, making personhood improvements, and achieving an indefinite lifespan via science and technology.

Option 1-2. Any sentient entity is entitled to enhance bodily and sensory capabilities, expand life, live free, and achieve eternal existence without suffering by utilizing science and technology.

Option 1-3.All human beings, sentient artificial intelligences, cyborgs, and other advanced sapient life forms have the right to pursue transcendence of physical and mental limitations.

Option 1-4. Human beings, sentient artificial intelligences, cyborgs, and other advanced sapient life forms are entitled to universal rights of ending involuntary suffering, making personhood improvements, and achieving an indefinite lifespan via science and technology, as well as any other behaviors constituting life enhancement.

Option 1-NO. No Article of this sort.

Abstain.

Rank-order the Article 2 Options that you support. Choose 1 for your most highly favored option, 2 for your second-most highly favored option, etc. You may include the option for No Article of this sort in your rank-ordering, and it does not need to be your most favored option if you do so. (For instance, some voters might favor some options but think that no language is preferable to some of the other options.)

If you choose Abstain, then do not rank-order any options, as you will be considered to have skipped this question.

Option 2-1 [Original Text by Zoltan Istvan]. Under penalty of law, no cultural, ethnic, or religious perspectives influencing government policy can impede life-extension science, the health of the public, or the possible maximum amount of life hours citizens possess.

Option 2-2. Under penalty of law, no cultural, ethnic, or religious perspectives influencing government policy can impede life-extension science, the health of the public, body modification, morphological enhancement, or the possible maximum amount of life hours citizens possess.

Option 2-3. Legal safeguards should be established to protect individual free choice in pursuing peaceful, consensual life-extension science, health improvements, body modification, and morphological enhancement. While all individuals should be free to formulate their independent opinions regarding the aforementioned pursuits, no hostile cultural, ethnic, or religious perspectives should be entitled to apply the force of law to erode the safeguards protecting peaceful, voluntary measures intended to maximize the number of life hours citizens possess.

Option 2-4. Legal safeguards should be established to protect individual free choice in pursuing peaceful, consensual life-extension science, health improvements, body modification, and morphological enhancement. While all individuals should be free to formulate their independent opinions regarding the aforementioned pursuits, no intolerant cultural, ethnic, or religious perspectives should be entitled to apply the force of law to erode the safeguards protecting peaceful, voluntary measures intended to maximize the number of life hours citizens possess.

Option 2-5. No government or irrational group should be permitted to systematically deny any person or persons access to a life-enhancing technology or the freedom to pursue scientific and technological avenues for their betterment.

Option 2-6. No government or irrational group should be permitted to systematically deny any sapient beingaccess to a life-enhancing technology or the freedom to pursue scientific and technological avenues for their betterment or self-actualization.

Option 2-7. No government or private entity should be permitted to systematically deny any person or persons access to a life-enhancing technology or the freedom to pursue scientific and technological avenues for their betterment.

Option 2-8. Under penalty of law, no cultural, ethnic, or religious perspectives influencing government policy can impede efforts at transcending physical and mental limitations, improving the health of the public, or the possible maximum amount of life hours citizens possess.

Option 2-NO. No Article of this sort.

Abstain.

Rank-order the Article 3 Options that you support. Choose 1 for your most highly favored option, 2 for your second-most highly favored option, etc. You may include the option for No Article of this sort in your rank-ordering, and it does not need to be your most favored option if you do so. (For instance, some voters might favor some options but think that no language is preferable to some of the other options.)

If you choose Abstain, then do not rank-order any options, as you will be considered to have skipped this question.

Option 3-1 [Original Text by Zoltan Istvan].Human beings, sentient artificial intelligences, cyborgs, and other advanced sapient life forms agree to uphold morphological freedomthe right to do with ones physical attributes or intelligence (dead, alive, conscious, or unconscious) whatever one wants so long as it doesnt hurt anyone else.

Option 3-2. Human beings, sentient artificial intelligences, cyborgs, and other advanced sapient life forms agree to uphold morphological freedomthe right to do with ones physical attributes or intelligence (dead, alive, conscious, or unconscious) whatever one wants so long as it does not harm others.

Option 3-3. Human beings, sentient artificial intelligences, cyborgs, and other advanced sapient life forms agree to uphold morphological freedomthe right to do with ones physical attributes or intelligence whatever one wants so long as it does not harm others.

Option 3-4. Human beings, sentient artificial intelligences, cyborgs, and other advanced sapient life forms agree to uphold morphological freedomthe right to do with ones physical attributes or intelligence whatever one wants so long as it does not harm others. This right includes the prerogative for a sentient intelligence to set forth in advance provisions for how to handle its physical manifestation, should that intelligence enter into a vegetative, unconscious, or similarly inactive state, notwithstanding any legal definition of death.

Option 3-5. Human beings, sentient artificial intelligences, cyborgs, and other advanced sapient life forms agree to uphold morphological freedomthe right to do with ones physical attributes or intelligence whatever one wants so long as it does not harm others. This right includes the prerogative for a sentient intelligence to set forth in advance provisions for how to handle its physical manifestation, should that intelligence enter into a vegetative, unconscious, or similarly inactive state, notwithstanding any legal definition of death. For instance, a cryonics patient has the right to determine in advance that the patients body shall be cryopreserved and kept under specified conditions, in spite of any legal definition of death that might apply to that patient under cryopreservation.

Option 3-NO. No Article of this sort.

Abstain.

If Article 3 on morphological freedom is adopted, shall one of the followingsentences be appended after the base text of the article?

Choose 1 for your most highly favored option, 2 for your second-most highly favored option, etc. You may include the option Do not add anysentence of this sort in your rank-ordering, and it does not need to be your most favored option if you do so. (For instance, some voters might favor some options but think that no language is preferable to some of the other options.)

Read the original here:

U.S. Transhumanist Party PUTTING SCIENCE, HEALTH ...