Many people wonder, "what is resveratrol?" For many years, grape seed extract was a hot seller (packaged as OPCs). In an interesting twist, it turns out that an important part of the grape was being left behind! The skin, which was being discarded in favor of the seeds, actually contains a powerful phytoalexin antioxidant known as resveratrol.
Resveratrol is a naturally occurring antioxidant that decreases the "stickiness" of blood platelets and helps blood vessels to remain open. In addition, resveratrol appears to have estrogen-like properties and may be helpful in the treatment of breast diseases. Also, studies indicate that resveratrol can profoundly inhibit glucose uptake in HL-60 and U937 cells. Thus, resveratrol may prevent or abate metabolic disorders such as obesity and type 2 diabetes.
In controlled studies, the benefits of resveratrol have been shown to reduce skin-cancer tumors by up to 98% and to stop production of leukemia cells. In addition, it works as a Cox inhibitor, thus halting the spread of cancer throughout the body.
And in 2003, the results of a study were released that showed that the benefits of resveratrol extended the lifespan of yeast cells by 70% by activating a "longevity gene" expressed during caloric restriction. Since mammals have the same "longevity gene" and since caloric restriction is known to extend the lifespan of mammals, scientists speculated humans might be able to receive the longevity benefits of caloric restriction simply by supplementing with resveratrol. And in fact, subsequently, resveratrol hit the news big time for its suspected ability to extend life and emerged as "the" hot antioxidant of the day, both in its supplement form and as a component of red wine, its most commonly identified natural source.
Resveratrol, however, is not an indispensable component of red grapes or wine. It is synthesized by plants on an as-needed basis, as a defense against parasites (primarily molds). Once abundant in red wine, it is now almost absent due to the use of pesticides. In other words, if you want resveratrol, you pretty much have to supplement. The most common source for supplemental trans-resveratrol and its natural analogs, now that red wine no longer works, is Japanese Knotweed, a plant at one time considered a major nuisance weed. Go figure!
When purchasing resveratrol, or products containing resveratrol, there are three things to keep in mind:
First, resveratrol comes in many different concentrations of its active component, from 8% (or less) to as high as 96% purity. One concentration is not necessarily better than the other, but you do have to use more of the lower concentration to get an equivalent dosage. For example, you will need 60 mg of a 50% resveratrol or 300 mg of a 10% extract to get the same dosage as 30 mg of a high purity resveratrol (as a side note, Jon Barrons Ultimate Antioxidant formula now has 150 mg of 50% resveratrol). It doesn't matter, though, how you get there, as long as you get there.
A bigger concern is the question of bioavailability. Pure trans-resveratrol tends not to have good bio-availability because it is rapidly metabolized by the liver. As found in nature, however, resveratrol is predominantly coupled with sugar. In this form, it is highly bio-available (making it a better choice) and, as an added bonus, more stable, which brings us to the third issue -- stability. This, of course, is the reason that Jon Barron chose a higher dose of less concentrated resveratrol -- better bioavailability.
There has been a lot of noise in many resveratrol ads concerning stability. And yes, in nature, resveratrol is subject to degradation when exposed to light, oxygen, or heat, which can alter it from its more active trans-resveratrol form to its lesser active cis-resveratrol form. Recent stability studies, however, have shown that resveratrol supplements, particularly in the sugar bound form, are generally stable for at least two years with no special packaging or storage required. In other words, this is, for the most part, a non-issue when it comes to choosing a resveratrol supplement.
Excerpt from:
What Is Resveratrol? | Herbal Library
- 6 Reasons to Supplement With Resveratrol | Men's Fitness [Last Updated On: August 18th, 2024] [Originally Added On: October 1st, 2017]
- resveratrol | eBay [Last Updated On: August 18th, 2024] [Originally Added On: November 20th, 2017]
- Natural Biology - 100% Pure and Natural Vitamins [Last Updated On: August 18th, 2024] [Originally Added On: November 20th, 2017]
- SuperPure Resveratrol Extract - The Synergy Company [Last Updated On: August 18th, 2024] [Originally Added On: November 20th, 2017]
- Resveratrol: Benefits and Uses - Verywell [Last Updated On: August 18th, 2024] [Originally Added On: November 20th, 2017]
- Resveratrol | Which Works Best | Facts About Side Effects [Last Updated On: August 18th, 2024] [Originally Added On: November 20th, 2017]
- Resveratrol - Wikipedia [Last Updated On: August 18th, 2024] [Originally Added On: November 20th, 2017]
- Sirtuin - Wikipedia [Last Updated On: August 18th, 2024] [Originally Added On: November 23rd, 2017]
- Resveratrolthe hype continues - Harvard Health Blog ... [Last Updated On: August 18th, 2024] [Originally Added On: November 26th, 2017]
- Resveratrol: Red Wine Antioxidant for Health - WebMD [Last Updated On: August 18th, 2024] [Originally Added On: November 26th, 2017]
- Resveratrol Lift Eye Lifting Balm - Caudalie | Sephora [Last Updated On: August 18th, 2024] [Originally Added On: November 29th, 2017]
- Resveratrol Lift Firming Serum - Caudalie | Sephora [Last Updated On: August 18th, 2024] [Originally Added On: December 6th, 2017]
- New Study Touts Big Health Benefits of Resveratrol [Last Updated On: August 18th, 2024] [Originally Added On: December 6th, 2017]
- Resveratrol | Memorial Sloan Kettering Cancer Center [Last Updated On: August 18th, 2024] [Originally Added On: December 13th, 2017]
- Resveratrol supplement, dosage and health benefits [Last Updated On: August 18th, 2024] [Originally Added On: December 15th, 2017]
- Purple Defense, Water-Soluble Source of Resveratrol [Last Updated On: August 18th, 2024] [Originally Added On: December 25th, 2017]
- This Ingredient Will Give You Smoother, Brighter Skin [Last Updated On: August 18th, 2024] [Originally Added On: January 21st, 2018]
- Diabetes (4 Types) and Thyroid Health [Last Updated On: August 18th, 2024] [Originally Added On: January 21st, 2018]
- Resveratrol: Benefits and Uses [Last Updated On: August 18th, 2024] [Originally Added On: February 24th, 2018]
- Resveratrol: Benefits and Uses - verywellfit.com [Last Updated On: August 18th, 2024] [Originally Added On: February 28th, 2018]
- Top 16 Scientific Health Benefits of Resveratrol (With ... [Last Updated On: August 18th, 2024] [Originally Added On: April 11th, 2018]
- Resveratrol Extract Powder - Z Natural Foods [Last Updated On: August 18th, 2024] [Originally Added On: April 26th, 2018]
- Resveratrol: Uses, Side Effects, Interactions, Dosage, and ... [Last Updated On: August 18th, 2024] [Originally Added On: April 28th, 2018]
- Pterostilbene vs Resveratrol [Last Updated On: August 18th, 2024] [Originally Added On: May 11th, 2018]
- Do Flavonoids in Red Wine Help You Live Longer? [Last Updated On: August 18th, 2024] [Originally Added On: May 11th, 2018]
- Can Resveratrol Fight Aging? | Berkeley Wellness [Last Updated On: August 18th, 2024] [Originally Added On: May 11th, 2018]
- Top 10 Resveratrol Health Benefits - Health Articles 101 [Last Updated On: August 18th, 2024] [Originally Added On: May 11th, 2018]
- Resveratrol Supplements | Resveratrol Supplement | Buy ... [Last Updated On: August 18th, 2024] [Originally Added On: May 11th, 2018]
- Resveratrol and Fertility | Egg quality, PCOS and ... [Last Updated On: August 18th, 2024] [Originally Added On: May 11th, 2018]
- Resveratrol - Phytochemical [Last Updated On: August 18th, 2024] [Originally Added On: June 15th, 2018]
- Resveratrol Lift Face Lifting Soft Cream - Caudalie | Sephora [Last Updated On: August 18th, 2024] [Originally Added On: June 23rd, 2018]
- Resveratrol - Herbs Database | RawlsMD [Last Updated On: August 18th, 2024] [Originally Added On: July 7th, 2018]
- Amazon.com: Reserveage - Resveratrol 500mg, Antioxidant ... [Last Updated On: August 18th, 2024] [Originally Added On: July 8th, 2018]
- Resveratrol Effectiveness, How It Works, and Drug ... [Last Updated On: August 18th, 2024] [Originally Added On: July 11th, 2018]
- Resveratrol: Dietary Supplements, Nutrition | eBay [Last Updated On: August 18th, 2024] [Originally Added On: July 27th, 2018]
- Resveratrol 99% (HPLC) | Sigma-Aldrich [Last Updated On: August 18th, 2024] [Originally Added On: August 26th, 2018]
- Resveratrol | A Beginners Guide (UPDATE: 2018) | 10 Things ... [Last Updated On: August 18th, 2024] [Originally Added On: August 26th, 2018]
- Resveratrol Effectiveness, Safety, and Drug Interactions on ... [Last Updated On: August 18th, 2024] [Originally Added On: September 20th, 2018]
- Resveratrol - Alzheimer's News Today [Last Updated On: August 18th, 2024] [Originally Added On: October 7th, 2018]
- Resveratrol does provide anti-aging benefits, study shows ... [Last Updated On: August 18th, 2024] [Originally Added On: November 9th, 2018]
- Resveratrol: The Healing Molecule In Red Wine - Red Supplements [Last Updated On: August 18th, 2024] [Originally Added On: November 9th, 2018]
- 7 Health Benefits of Resveratrol Supplements [Last Updated On: August 18th, 2024] [Originally Added On: November 27th, 2018]
- Resveratrol - Evolutionary.org [Last Updated On: August 18th, 2024] [Originally Added On: December 3rd, 2018]
- Health effects of wine - Wikipedia [Last Updated On: August 18th, 2024] [Originally Added On: December 8th, 2018]
- foodsthatfightcancer_grapes_and_grape_juice | American ... [Last Updated On: August 18th, 2024] [Originally Added On: January 24th, 2019]
- Resveratrol Benefits, Resveratrol Sources & More - Dr. Axe [Last Updated On: August 18th, 2024] [Originally Added On: March 5th, 2019]
- Red wine and resveratrol: Good for your heart? - Mayo Clinic [Last Updated On: August 18th, 2024] [Originally Added On: March 23rd, 2019]
- Resveratrol Benefits, Side Effects and Sources - Dr. Axe [Last Updated On: August 18th, 2024] [Originally Added On: September 14th, 2019]
- Resveratrol Supplements Are Finally Put to the Test ... [Last Updated On: August 18th, 2024] [Originally Added On: September 29th, 2019]
- Best Resveratrol Supplement Benefits vs Side Effects Review [Last Updated On: August 18th, 2024] [Originally Added On: September 29th, 2019]
- Resveratrol Supplements | Resveratrol Benefits | Piping ... [Last Updated On: August 18th, 2024] [Originally Added On: September 29th, 2019]
- Resveratrol - an overview | ScienceDirect Topics [Last Updated On: August 18th, 2024] [Originally Added On: October 4th, 2019]
- Resveratrol Foods: The 17 Highest Sources To Supplement With [Last Updated On: August 18th, 2024] [Originally Added On: October 4th, 2019]
- Resveratrol Side Effects and Health Hazards [Last Updated On: August 18th, 2024] [Originally Added On: October 4th, 2019]
- How to Choose the Best Resveratrol Supplements (2019 Update) [Last Updated On: August 18th, 2024] [Originally Added On: October 4th, 2019]
- Ranking the best resveratrol supplements of 2019 [Last Updated On: August 18th, 2024] [Originally Added On: October 4th, 2019]
- 10 Resveratrol Benefits for Heart, Mind, & the Fountain of Youth [Last Updated On: August 18th, 2024] [Originally Added On: October 14th, 2019]
- 21 Resveratrol Benefits + Dosage, Side Effects - SelfHacked [Last Updated On: August 18th, 2024] [Originally Added On: October 24th, 2019]
- Alcoholic People are Shifting to Drinking Red Wine Daily to Improve their Health - One World Herald [Last Updated On: August 18th, 2024] [Originally Added On: October 29th, 2019]
- Nature's Viagra: 7 Foods and Supplements to Boost Your Libido - Healthline [Last Updated On: August 18th, 2024] [Originally Added On: October 29th, 2019]
- How One Company Is Working To Improve The Quality & Duration Of Sleep For Americans - GirlTalkHQ [Last Updated On: August 18th, 2024] [Originally Added On: October 29th, 2019]
- Use of natural extracts as feed additives - All about feed [Last Updated On: August 18th, 2024] [Originally Added On: October 29th, 2019]
- Is The World Ready For A Super-Wine? Raise A Glass To Israeli Vino Innovation | Health News - NoCamels - Israeli Innovation News [Last Updated On: August 18th, 2024] [Originally Added On: November 2nd, 2019]
- One type of food could help reverse aging, thanks to resveratrol - Inverse [Last Updated On: August 18th, 2024] [Originally Added On: November 2nd, 2019]
- How and why to boost your intake of antioxidants - Seattle Times [Last Updated On: August 18th, 2024] [Originally Added On: November 3rd, 2019]
- 6 Winter Fruits That You May Include In Your Diabetes Diet - NDTV Food [Last Updated On: August 18th, 2024] [Originally Added On: November 8th, 2019]
- Bordeaux wine launched to the International Space Station for science - ZME Science [Last Updated On: August 18th, 2024] [Originally Added On: November 8th, 2019]
- Resveratrol Market Report to Share Key Aspects of the Industry with the details of Influence Factors - Health News Office [Last Updated On: August 18th, 2024] [Originally Added On: November 8th, 2019]
- Resveratrol Market is Projected to Register at a Healthy CAGR of 8.1% During the Forecast Period 2018 2028 - Global Banking And Finance Review [Last Updated On: August 18th, 2024] [Originally Added On: November 8th, 2019]
- Paranormal wine: Space and wine x2 - Aspen Daily News [Last Updated On: August 18th, 2024] [Originally Added On: November 8th, 2019]
- Rimrock Gold Corp. Announces the Launch of Acqua CBD Coffee Infused with Resveratrol - GlobeNewswire [Last Updated On: August 18th, 2024] [Originally Added On: November 8th, 2019]
- Heres how you can shield yourself from air pollution with these natural remedies - Hindustan Times [Last Updated On: August 18th, 2024] [Originally Added On: November 13th, 2019]
- Resveratrol Market Strategies and Insight Driven Transformation 2019-2027 - The Denton Chronicle [Last Updated On: August 18th, 2024] [Originally Added On: November 13th, 2019]
- Growth Opportunities in the Resveratrol Supplements Market Strategic Analysis and Forecast to 2028 - TheFinanceTime [Last Updated On: August 18th, 2024] [Originally Added On: November 13th, 2019]
- From Avocation To Vocation: How I Turned My Hobby Into A Career With Dr. Glen Miller of Vera Roasting Company - Thrive Global [Last Updated On: August 18th, 2024] [Originally Added On: November 13th, 2019]
- Trans Resveratrol Market Growing Popularity and Emerging Trends 2019 to 2025 Business and Transportation - .Automotiveindustrytrend [Last Updated On: August 18th, 2024] [Originally Added On: November 13th, 2019]
- 5 Effective Ways To Fight Inflammation - Medical Daily [Last Updated On: August 18th, 2024] [Originally Added On: November 23rd, 2019]
- What the industry needs to know about polypharmacology - NutraIngredients-usa.com [Last Updated On: August 18th, 2024] [Originally Added On: November 23rd, 2019]
- Cardioprotective properties found in pterostilbene: Study - NutraIngredients-usa.com [Last Updated On: August 18th, 2024] [Originally Added On: November 23rd, 2019]
- Resveratrol Supplements Expected to Witness a Fast-paced Growth Over the Forecast Period 2019 2028 - Tech Admirers [Last Updated On: August 18th, 2024] [Originally Added On: November 23rd, 2019]