MDMA is a truly remarkable medicine for working with difficult emotional experiences. The clinical results have far exceeded other interventions for a range of uses (see the research section at the bottom of this page).

MDMA is a synthetic psychedelic, first developed by the pharmaceutical company Merck in 1912. It has been widely studied since then, particularly for psychotherapeutic uses. With the rate of academic research growing rapidly, it is likely that MDMA will become FDA approved for therapeutic use within the next few years, and MAPS.org is focused on moving it through the approval process. MDMA is being widely tested for post-traumatic stress, with results that surpass any other existing treatment method.

MDMA is a particularly appealing psychedelic for therapists and researchers because the subjective mental experience feels fairly stable, while creating a dramatic increase in emotional openness and a reduction in fear and anxiety.

Before you begin, be sure to read our safety section and see the special safety considerations for MDMA at the bottom of this page.

Because MDMA has anti-anxiety and anti-fear effects, it is generally considered safe to use a full dose your first time and each time you use MDMA (generally 75mg - 125mg depending on the individual). It is important to measure the dose carefully. Milligram-precision scales cost about 20 dollars (heres an Amazon search for milligram scale).

Some therapy protocols add a booster dose of about 60mg of MDMA 2-3 hours after the first dose to extend the period of therapeutic effects and provide more time for deep exploration.

MDMA will typically be in the form of a powder, pill, or crystal. Again, be sure that you are receiving pure MDMA, not mixed with other drugs or stimulants like caffeine. 'Molly' is another term for pure MDMA, distinguished from 'Ecstasy' which often contains MDMA but is not pure MDMA. If the MDMA is in pill form, youll have to be confident of the reported dosage, as fillers are added to create a pill and weighing the pill will not indicate the MDMA content. As always, do not take any MDMA if you are unsure of quantity or purity.

Once the MDMA has worn off, be sure that you drink lots of water and get a long peaceful sleep at night. MDMA can be mentally tiring and you need to rejuvenate.

Most people find that they have an afterglow from their MDMA experience that can last days or weeks, improving their mood and outlook and keeping them very open to others.

On the other hand, some people feel mentally drained by MDMA and have a foggy headed feeling for a day or two afterwards. Others will feel emotionally drained, and have a depressed mood for up to a week after the experience. Sometimes, these feelings begin two days after the experience, but not the day after. To combat this, some people who feel sensitive to that after-effect will take 5-HTP or L-Tryptophan (both are common supplements available from any source) for a few days after MDMA in an attempt to restore their serotonin levels. People who do feel drained after an MDMA session generally report that precise the MDMA dose can affect how they feel afterwards. Too much may leave them more drained than necessary. This is another reason to start with a modest, precisely measured dose to begin.

Nearly everyone, no matter how they feel the following week, finds that the thoughts, feelings, and emotional release that they experience on MDMA persists afterwards. In particular, any realizations that they had during the experiences tend to prove real and lasting.

Most remarkably, painful emotional associations with life experiences -- traumas, breakups, divorces, etc -- are dramatically reduced if that issue has been explored during the experience. You will find that when you think about that same painful experience after exploring it on MDMA, you will not have the same flood of emotional pain and tension that you would have had beforehand. The memory will be intact but the emotional strings will be looser.

Even for extreme emotional trauma, this holds true. In a recent research study for patients with PTSD, 83% of patients experienced reduced symptoms after just 3 MDMA sessions combined with therapy, vs. only 25% of patients who had therapy alone. Quite simple, MDMA is the most effective treatment for PTSD ever developed. Compare this level of success to traditional anti-depressants which have strong side effects and are dosed every day for years at a time (for a total of hundreds or thousands of doses) and which have very low rates of effectiveness, often just slightly above placebo.

In addition to our standard safety suggestions, there are three particularly important precautions for MDMA use:

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How to Use MDMA (Molly) - How to Use Psychedelics