Earlier this year, Canopy Growth (NYSE: CGC) co-founder and former CEO Bruce Linton invested in a neuropharmaceutical company, Mind Medicine Inc.
MindMed is a psychedelicresearch company thats developing non-hallucinogenic medicine from psychedelic sources. The company has also welcomed Linton to its board of directors.
The 53-year-old entrepreneur told Benzinga heplans to spend 2020 searching for new business ideas andwill start a new business in 2021.
Linton has long found the psychedelics sector to be compelling, Linton said.
Prohibition or poor regulatory frameworks globallydon't mean that the underlying regulated substances are in fact terrible. The therapeutic potential of psychedelics is greater than cannabinoids, for sure.
Supporting a company developing psychedelic substances for medicinal purposes is the best way to rediscover the therapeutic potential of certain plants and mushrooms that have long been banned by the FDA, he said.
"The whole point of this exercise is to build a large platform company that welcomes many, many research projects ... and turns them into finished outcomes that create therapeutic benefit," Linton said in reference to his involvement with Mind Medicine.
Once the therapeutic properties of psychedelics in treating conditions like ADHD, opioid addiction and severe depression are acknowledged, their histories of prohibition will be irrelevant, the cannabis exec said.
In that sense, the process for legalizing these substances is similar tocannabis, he said: achange in public perception is the main tool in fighting prohibition.
"At the end of the day, we're having the same conversation, with the same cohort."
See Also: The Keys To Understanding Psilocybin's Medical Value, Market Potential
Mind Medicine is researching the psychiatric potential of LSD and 18-MC, a synthesized version of ibogaine that is showing promising results in the treatment of opioid addiction.
The company recently raised $6.2 million to conduct Phase 2 clinical trials of18-MC.
Kevin OLeary, co-host of ABCs "Shark Tank," is among the companys investors.
Benzinga spoke with Mind Medicine co-founder and director JR Rahn.
Rahn, who has a tech background, decided to focus his entrepreneurial efforts on psychedelics after seeing many of his Silicon Valley colleagues microdosing LSD and other psychedelic compounds to increase focus and performance.
After researching the environment, Rahn said he decided to focus on the 18-MC molecule because of its promisein treating opioid addiction.
In 2013, the National Institute on Drug Abuse awarded a $6.7-million research grant to a pharmaceutical research company, Savant, to subsidize preclinical development of 18-MC for the treatment of obesity and substance use disorders.
Mind Medicine sprouted from Savant, Rahn said.
I co-founded the company with the Savant CEO. Savant sold the 18-MC program to MindMed in a share deal. Savants entire team has joined MindMed and is 100% focused on MindMed now. We used that money to do all this preclinical work and conduct a Phase 1 trial in humans to demonstrate that it was safe.
Rahn said his company aims to go public on Canadas NEO exchange in the first quarter of 2020, although the details are definitive.
The Benzinga Cannabis Capital Conference is heading to Miami Feb. 24-25 for its sixth installment.Click hereto learn more.
In recent years, psilocybinthe psychedelic molecule derived from magic mushroomshas been shaping up to be thestar compound in the psychedelic revolution of psychiatric treatment.
Psilocybin research is paving the way to psychedelic treatment in general and the development of psychedelics as an industry, Rahn said.
Yet hes placing his trust in the possibilities offered by 18-MC as a non-hallucinogenic psychedelic taken in microdoses.
Linton also commented on psilocybins commercial value.
The path to commercialization for the compound is financially unclear and difficult, he said. In Linton's view, commercial success relies on the possibility of modifying the original compounds.
"It's a very difficult molecule to alter. But there are a variety of other psychedelics that can be amended structurally to reduce their hallucinogenic effect, or they can actually have dose metering technologies that allow for well-structured delivery," he said.
"That to me gets to be very interesting commercially."
The definition of microdosing has yet to be standardized.
One approach would be to consider a "micro" dose of psychedelics to be one that's so low a hallucinogenic effect cannot be perceived, yet a therapuetic effect is achieved.
Yet as multiple scholars stated in a review paper on the subject, "there is no agreed scientific consensus on what microdosing is."
Linton is well aware of this fact.
"Whats micro?" he asks rhetorically. "How are you actually managing the dose? What's the frequency on micro? What are the primary indications that you're using it against? And what's the baseline of efficacy compared to other medicines? All that work is undone."
For Linton, the lack of knowledge on the subjectis more of an opportunity than a drawback.
"That means this is a bad idea currently because we have to do the work to show thats a great idea. If it was already a great idea, that means everybody did all the work. Im a big fan of investing in bad ideas."
Microdosing psychedelics offers vast potential not only in substance addiction, but also in the treatment of anxietyand adult ADHD.
The theory that this type of treatment can be dangerous to the heart especially using substances like LSD and 18-MC is unproven, Rahntold Benzinga.
"One of the things that well be doing is rigorous science and a Phase 2 clinical trial to demonstrate if there are issues relating to the heart or not. Because there aretheories that it might but there's been very little rigorous science on the microdosing subject."
See Also: Bruce Linton On His Next Steps, Says 'I'm Cheering For Entrepreneurs'
The pharmaceutical industry will be especially interested in psychedelics, Linton said.
Pharmaceutical companies need a pipeline of drugs that address mental health conditions and addiction, he said.
Rahn said there's a lack of investment in addiction medicine.
"On the opioid market, theres Suboxone. There are studies that demonstrate that it has a 90% failure rate. That's not good. We're not going to solve the opioid crisis that way."
For Linton, the debate around whether psychedelics have an effective impact on humans is no longer relevant.
"Humans have been using [psychedelics] for 3,000 or 4,000 years. Listen, if you don't think it does have an effect, then please go have an acid trip and tell me how it didn't affect you, he said. What I want to know is what amount, in what way, to get what outcome?"
Featured photo by Robina Weermeijer viaUnsplash.
2019 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.
Read more:
- 8 Mystical Herbs and Legal Psychedelics For Lucid Dreaming [Last Updated On: December 8th, 2016] [Originally Added On: December 8th, 2016]
- Psychedelics: LSD, Mushrooms, Salvia | Facts | Drug Policy ... [Last Updated On: December 10th, 2016] [Originally Added On: December 10th, 2016]
- FS Book Company - Marijuana Books [Last Updated On: December 12th, 2016] [Originally Added On: December 12th, 2016]
- Psychedelic - PsychonautWiki [Last Updated On: December 27th, 2016] [Originally Added On: December 27th, 2016]
- From Alzheimer's To Psychedelics, 2016 Was A Good Year For ... [Last Updated On: January 3rd, 2017] [Originally Added On: January 3rd, 2017]
- LSD - Psychedelic Effects - The Good Drugs Guide [Last Updated On: January 5th, 2017] [Originally Added On: January 5th, 2017]
- THC - Psychedelics [Last Updated On: January 29th, 2017] [Originally Added On: January 29th, 2017]
- Psychedelics | Pharmacological Reviews [Last Updated On: January 30th, 2017] [Originally Added On: January 30th, 2017]
- Dorian Yates reveals all on steroids, body dysmorphia, psychedelics, cannabis and yoga - Express.co.uk [Last Updated On: February 7th, 2017] [Originally Added On: February 7th, 2017]
- Psychedelic drug therapy including magic mushrooms, LSD and ... - CBS News [Last Updated On: February 7th, 2017] [Originally Added On: February 7th, 2017]
- Psychedelics Being Tested For Use In Treating Various Conditions - CBS Local [Last Updated On: February 8th, 2017] [Originally Added On: February 8th, 2017]
- The psychedelic renaissance - Boulder Weekly [Last Updated On: February 9th, 2017] [Originally Added On: February 9th, 2017]
- Buy psychedelics online : Chinglabs.com [Last Updated On: February 12th, 2017] [Originally Added On: February 12th, 2017]
- Psychedelic drugs like magic mushrooms and LSD have key ... - Yahoo Finance [Last Updated On: February 13th, 2017] [Originally Added On: February 13th, 2017]
- Psychedelics a Viable Therapeutic Option for Depression - Psychiatry Advisor [Last Updated On: February 14th, 2017] [Originally Added On: February 14th, 2017]
- Is Silicon Valley Onto Something With Its LSD Microdosing? - Newsweek [Last Updated On: February 15th, 2017] [Originally Added On: February 15th, 2017]
- News Releases - Noozhawk [Last Updated On: February 16th, 2017] [Originally Added On: February 16th, 2017]
- A Revolution in the Science of Psychedelics is Happening in Boulder - 303 Magazine [Last Updated On: February 16th, 2017] [Originally Added On: February 16th, 2017]
- When Reality Is More Intense Than Psychedelics: Strand Of Oaks ... - NPR [Last Updated On: February 17th, 2017] [Originally Added On: February 17th, 2017]
- Psychedelics Help Reduce Opioid Addiction, According to New Study - AlterNet [Last Updated On: February 22nd, 2017] [Originally Added On: February 22nd, 2017]
- Psychedelics May Help Reduce Opioid Addiction, According To ... - Huffington Post [Last Updated On: February 23rd, 2017] [Originally Added On: February 23rd, 2017]
- Psychedelics Help Reduce Opioid Addiction, According to New Study - eNews Park Forest [Last Updated On: February 24th, 2017] [Originally Added On: February 24th, 2017]
- Psychedelics Could Play A Role In Tackling The Opioid Epidemic - Huffington Post [Last Updated On: February 24th, 2017] [Originally Added On: February 24th, 2017]
- Meet The People's Champion of Psychedelic Drugs - Narratively [Last Updated On: February 27th, 2017] [Originally Added On: February 27th, 2017]
- How psychedelics like psilocybin and LSD actually change the way ... - Yahoo Finance [Last Updated On: February 27th, 2017] [Originally Added On: February 27th, 2017]
- First U. student group on studying psychedelics holds open house - The Daily Princetonian [Last Updated On: February 27th, 2017] [Originally Added On: February 27th, 2017]
- How psychedelics like psilocybin and LSD actually change the way people see the world - Businessinsider India [Last Updated On: February 28th, 2017] [Originally Added On: February 28th, 2017]
- Psychedelics Help Reduce Opioid Addiction, According to New ... [Last Updated On: February 28th, 2017] [Originally Added On: February 28th, 2017]
- WATCH: A Public Policy Expert Explains How to Safely Deregulate LSD and Other Psychedelics - AlterNet [Last Updated On: March 7th, 2017] [Originally Added On: March 7th, 2017]
- Quotes About Psychedelics (48 quotes) [Last Updated On: March 7th, 2017] [Originally Added On: March 7th, 2017]
- Inside the Psychedelic Underground - RollingStone.com [Last Updated On: March 9th, 2017] [Originally Added On: March 9th, 2017]
- What Psychedelics Really Do to Your Brain - Rolling Stone - RollingStone.com [Last Updated On: March 10th, 2017] [Originally Added On: March 10th, 2017]
- Hallucinogens Help, According to a Mom's Memoir and Son's Documentary - Bedford + Bowery [Last Updated On: April 8th, 2017] [Originally Added On: April 8th, 2017]
- Meditation and the psychedelic drug ayahuasca seem to change the brain in surprisingly similar ways - Businessinsider India [Last Updated On: April 8th, 2017] [Originally Added On: April 8th, 2017]
- Tripping out: the highs and lows of psychedelic therapy - Marie Claire UK [Last Updated On: April 8th, 2017] [Originally Added On: April 8th, 2017]
- Stop Policing Psychedelic Science - Motherboard [Last Updated On: June 6th, 2017] [Originally Added On: June 6th, 2017]
- America's Trippiest Chemist: Making Psychedelics 'Was Fun' - Motherboard [Last Updated On: June 6th, 2017] [Originally Added On: June 6th, 2017]
- The Three Types of Hallucinogens: Psychedelics ... [Last Updated On: June 7th, 2017] [Originally Added On: June 7th, 2017]
- Cary Grant was one of the first to benefit from LSD therapy - Quartz [Last Updated On: June 11th, 2017] [Originally Added On: June 11th, 2017]
- What it's like to take psychedelics in small doses at breakfast - New Scientist [Last Updated On: June 14th, 2017] [Originally Added On: June 14th, 2017]
- 'Changing Our Minds' explores psychedelic drugs and spiritual healing - Religion News Service [Last Updated On: June 14th, 2017] [Originally Added On: June 14th, 2017]
- Q&A With Psychedelic Stand-Up and LaughFest Headliner Shane Mauss - Flagpole Magazine [Last Updated On: June 20th, 2017] [Originally Added On: June 20th, 2017]
- Q&A: LaughFest comedian talks science and psychedelics - Red and Black [Last Updated On: June 20th, 2017] [Originally Added On: June 20th, 2017]
- 'Changing Our Minds' explores psychedelic drugs and spiritual healing - The Daily Tribune [Last Updated On: June 21st, 2017] [Originally Added On: June 21st, 2017]
- Shane Mauss brings Good Trip Comedy Tour to town - Chattanooga Times Free Press [Last Updated On: June 22nd, 2017] [Originally Added On: June 22nd, 2017]
- 'Changing Our Minds' explores psychedelic drugs and spiritual healing - The Oakland Press [Last Updated On: June 22nd, 2017] [Originally Added On: June 22nd, 2017]
- Director Ana Lily Amirpour on Cannibalism, Psychedelics, and 'Horrifying' Racism Allegations - Jezebel [Last Updated On: June 23rd, 2017] [Originally Added On: June 23rd, 2017]
- Majority of Americans ready to embrace psychedelic therapy - YouGov US [Last Updated On: June 24th, 2017] [Originally Added On: June 24th, 2017]
- The Refugee Funding America's Psychedelic Renaissance - VICE [Last Updated On: June 24th, 2017] [Originally Added On: June 24th, 2017]
- Open Your Mind This Weekend at Europe's Largest Psychedelic Conference - VolteFace Magazine (blog) [Last Updated On: June 27th, 2017] [Originally Added On: June 27th, 2017]
- Psychedelics and Virtual Reality Make a Trendy but Illegal Therapy - Inverse [Last Updated On: June 27th, 2017] [Originally Added On: June 27th, 2017]
- The war on drugs is back. Will psychedelic drug research survive? - The Verge [Last Updated On: June 29th, 2017] [Originally Added On: June 29th, 2017]
- Tune in, Turn on, Stay in School - Study Breaks [Last Updated On: July 2nd, 2017] [Originally Added On: July 2nd, 2017]
- Cannabist Show: He's psychedelic comedian Shane Mauss - The Cannabist [Last Updated On: July 2nd, 2017] [Originally Added On: July 2nd, 2017]
- The brain on DMT: mapping the psychedelic drug's effects - Wired.co.uk [Last Updated On: July 3rd, 2017] [Originally Added On: July 3rd, 2017]
- Psychedelics Could Help Asia's Mental Health Care, But Stigma Remains Roadblock - TheFix.com [Last Updated On: July 3rd, 2017] [Originally Added On: July 3rd, 2017]
- Is LSD the new coffee? - FactorDaily [Last Updated On: July 4th, 2017] [Originally Added On: July 4th, 2017]
- My grandfather was a death row doctor. He tested psychedelic drugs on Texas inmates. - Texas Tribune [Last Updated On: July 5th, 2017] [Originally Added On: July 5th, 2017]
- About Us | Trusted News Source for Psychedelic Research ... [Last Updated On: July 6th, 2017] [Originally Added On: July 6th, 2017]
- Do Psychedelic Drugs Cause the 'Prophetic Effect'? - Breaking Israel News [Last Updated On: July 11th, 2017] [Originally Added On: July 11th, 2017]
- Are psychedelics the new medical marijuana? - WTSP 10 News [Last Updated On: July 14th, 2017] [Originally Added On: July 14th, 2017]
- Psychiatrists Say Cannabis Medicine Has Psychedelic Properties - The Marijuana Times [Last Updated On: July 15th, 2017] [Originally Added On: July 15th, 2017]
- Can Psychedelics Be Therapy? Allow Research to Find Out - New York Times [Last Updated On: July 17th, 2017] [Originally Added On: July 17th, 2017]
- Countdown To (Legalized) Ecstasy! Rick Doblin, MAPS, & the Psychedelic Renaissance [Podcast] - Reason (blog) [Last Updated On: July 20th, 2017] [Originally Added On: July 20th, 2017]
- Should We Reclassify Marijuana as a Hallucinogen? - Big Think [Last Updated On: July 20th, 2017] [Originally Added On: July 20th, 2017]
- Do You Take Drugs at Festivals? This Initiative is Working on Keeping You Safe - PoliticalCritique.org [Last Updated On: July 20th, 2017] [Originally Added On: July 20th, 2017]
- Psychedelic drugs could tackle depression in a way that antidepressants can't - INSIDER [Last Updated On: July 22nd, 2017] [Originally Added On: July 22nd, 2017]
- Psychedelic Shine takes a trip to the skies in Boulder - Boulder Daily Camera [Last Updated On: July 22nd, 2017] [Originally Added On: July 22nd, 2017]
- Reasons to Consider Trying Psychedelics - FoxWeekly [Last Updated On: July 27th, 2017] [Originally Added On: July 27th, 2017]
- Psychedelics and Normality - HuffPost [Last Updated On: July 27th, 2017] [Originally Added On: July 27th, 2017]
- New book about psychedelics and weird human experiences - Boing Boing [Last Updated On: July 27th, 2017] [Originally Added On: July 27th, 2017]
- Scientists Want You to Give Them Money to Study ... [Last Updated On: July 29th, 2017] [Originally Added On: July 29th, 2017]
- What Has Awe Done for Me Lately? - HuffPost [Last Updated On: August 1st, 2017] [Originally Added On: August 1st, 2017]
- For children, it's beyond psychedelics - The Hans India - The Hans India [Last Updated On: August 1st, 2017] [Originally Added On: August 1st, 2017]
- Expanding consciousness - 48 Hills [Last Updated On: August 2nd, 2017] [Originally Added On: August 2nd, 2017]
- THE FUTURE OF PSYCHEDELICS: Are LSD and Mushrooms The New Prozac? - Dope Magazine [Last Updated On: August 5th, 2017] [Originally Added On: August 5th, 2017]
- Psychedelic drugs saved my life. So why aren't they prescribed? - Wired.co.uk [Last Updated On: August 9th, 2017] [Originally Added On: August 9th, 2017]
- LSD as therapy: How scientists are reclaiming psychedelics ... [Last Updated On: August 9th, 2017] [Originally Added On: August 9th, 2017]
- The foundation of Western philosophy is probably rooted in psychedelics - Quartz [Last Updated On: August 12th, 2017] [Originally Added On: August 12th, 2017]
- Crazy Enough to be Correct - HuffPost [Last Updated On: August 15th, 2017] [Originally Added On: August 15th, 2017]