Pharmacogenomics karly

The term Pharmacogenomics comes from merging the study of drugs (pharmacology) and the study of how traits are inherited (genetics). Pharmacogenomic testing is intended to predict or explain how a person will respond to medicines based on that persons specific genetic characteristics. Pharmacogenomics links specific gene sequences to how the body acts on a drug: absorption, distribution, metabolism, elimination and to how the body responds to the drug: basically desirable or undesirable.

Pharmacogenomic profiles hold the potential to improve prescribing practices for most, if not all drugs. Pretreatment Pharmacogenomic testing has the potential to predict a patients response to or optimal dosing for a specific drug(s). Also, Pharmacogenomic profiles give valuable information on how to avoid or minimize the incidence of adverse drug reactions (ADRS), a leading cause of morbidity and mortality in the United States. This enables healthcare providers to prescribe drug therapy based on unique genetics, making the experience more personalized to each patient.

Sample collection for Pharmacogenomic testing is easy and non-invasive. A simple collection of the buccal (cheek) cells on two different swabs is all that is necessary. The swabs are then placed in DNA-stabilizing solution and ready to be shipped overnight for testing.

Compass Laboratory Services will run a series of tests to determine the genetic variation of the sample. Those results are then analyzed and interpreted to create a Pharmacogenomic profile which the healthcare provider can use as a foundation for optimum drug therapy. Results are reported in an easy-to-read format that breaks down medications into guidance levels of normal, intermediate and poor metabolizers.

Excerpt from:
What Is Pharmacogenomics? | Compass Lab Services, LLC