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CRC is the third most common cancer diagnosed in both men and women in the United States. As of 2011, The American Cancer Society estimates 101,700 new cases of colon cancer and 39,510 new cases of rectal cancer.  CRC is expected to cause about 49,380 deaths during 2011.

CRC is preventable through regular screening. Unlike many other types of cancer, CRC is easily curable if found early and can be prevented by removing precancerous polyps. Both polyps and early-stage cancers are usually asymptomatic. Compared with these lesions, cancers that have grown large enough to cause symptoms have a much worse prognosis.

This contrast highlights the need for screening in asymptomatic persons. In fact, if everyone aged 50 or older had regular screening tests, at least one-third of deaths from this CRC could be avoided.

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