Golden Globe winner and Oscar nominee Bob Hoskins has retired from acting after being diagnosed with Parkinson's disease.

"He wishes to thank all the great and brilliant people he has worked with over the years, and all of his fans who have supported him during a wonderful career," his rep said in a statement to the BBC. "Bob is now looking forward to his retirement with his family, and would greatly appreciate that his privacy be respected at this time."

Hoskins, 69, was diagnosed in the fall.

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A native of Suffolk, England, Hoskins started acting in the 1960s and spent the '70s on British TV series, including Villains. His breakthrough role was as gangster Harold Shand in 1980's The Long Good Friday, which co-starred Helen Mirren. He won a Golden Globe, a BAFTA, a Cannes Film Festival award and earned a Best Actor Oscar nomination for his portrayal of George, a criminal who gets involved with a high-class call girl in 1986's Mona Lisa.

He earned a second Globe nomination for perhaps his most memorable role: private investigator Eddie Valiant in the 1998 live-action and animated hit Who Framed Roger Rabbit.

Other credits include Mermaids, Hook, Nixon and 2005's Mrs. Henderson Presents, for which he earned his third Globe nod.

Hoskins' final film was this summer's hit Snow White and the Huntsman, in which he played the dwarf Muir.

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Bob Hoskins Retires Due to Parkinson's Disease