MONDAY, March 12 (HealthDay News) -- People taking popular cholesterol-lowering drugs called statins may have a slightly lower risk than others of developing Parkinson's disease, new research suggests.

This effect may be even more pronounced among people younger than 60, according to the study published in the March issue of Archives of Neurology.

However, the risk reduction was modest and may have been due to chance, the authors said, noting that more research is warranted, especially because statins can cause adverse side effects.

"There is no clear verdict," said Dr. Stuart Isaacson, director of the Parkinson's Disease and Movement Disorders Center of Boca Raton, who was not involved in the study.

"Right now we don't have any good evidence that there is anything we can do to reduce the risk of developing Parkinson's disease, but research is ongoing," added Isaacson, also an associate professor of neurology at Florida International University's Herbert Wertheim College of Medicine in Miami.

For the study, researchers led by Dr. Xiang Gao, of Brigham and Women's Hospital and Harvard University School of Public Health in Boston, analyzed data on more than 38,000 men and almost 91,000 women enrolled in the Health Professionals Follow-up Study and the Nurses' Health Study in 1994.

During 12 years of follow-up, 644 people were diagnosed with Parkinson's disease. People taking cholesterol-lowering drugs, especially those younger than 60, were less likely to develop the neurological disorder than those not using cholesterol drugs, the researchers found.

Nearly one million people in the United States have Parkinson's disease, a chronic and progressive movement disorder, and no one knows what causes it.

The researchers can't say exactly how -- or even if -- statins reduce the risk of Parkinson's. It's thought these drugs may have potent anti-inflammatory effects, which could protect the brain.

The study had some limitations, the authors acknowledged. For example, only about 70 percent of people who were taking drugs to lower cholesterol were actually on statins at the study's start.

Read the rest here:
Can Statins Prevent Parkinson's Disease?