After delivering almost 5,000 pounds of supplies and experiments to the International Space Station during a month-long stay, the SpaceX Dragon cargo spacecraft is set to leave the orbital laboratory on Saturday, Oct. 25.

The Dragon spacecraft is scheduled to detach from the Earth-facing side of the station's Harmony module and unberth through commands sent by robotic ground controllers in mission control at NASA's Johnson Space Center in Houston operating the Canadarm 2 robotic arm. Mission control will maneuver Dragon into place then turn it over to Expedition 41 robotic arm operators Reid Wiseman and Barry Wilmore of NASA for release, which is scheduled for 9:56 a.m. EDT.

NASA Television will provide live coverage of Dragon's departure beginning at 9:30 a.m.

Space station and SpaceX officials delayed Dragons departure four days from the originally scheduled date of Oct. 21 because of high sea states in the splashdown and recovery zone west of Baja California.

Dragon is the only space station resupply spacecraft able to return to Earth intact. It will return about 3,276 pounds of cargo, including science samples from human research, biology and biotechnology studies, physical science investigations and education activities sponsored by NASA and the Center for the Advancement of Science in Space, the nonprofit organization responsible for managing research aboard the U.S. national laboratory portion of the space station.

Dragon will execute three thruster firings to move away from the station to a safe distance for its deorbit burn at 2:43 p.m. The capsule will splash down in the Pacific Ocean around 3:39 p.m. Neither the deorbit burn nor the splashdown will broadcast on NASA TV.

Dragon launched on the SpaceX Falcon 9 rocket from the Cape Canaveral Air Force Station, Florida on Sept. 21 on the companys fourth commercial resupply mission to the station. It arrived at the station Sept. 23.

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NASA TV Coverage Set for U.S. Cargo Ships Departure from International Space Station