NEW YORK, Feb. 13, 2012  /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

Nanotechnology for Drug Delivery : Global Market for Nanocarriers

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Nanocarriers will account for 40% of a $136 billion nanotechnology-enabled drug delivery market by 2021. We forecast the total market size in 2021 to be US$136 billion, with a 60/40 split between nanocrystals and nanocarriers respectively, although developing new targeted delivery mechanisms may allow more value to be created for companies and entrepreneurs.

Of the 10 nanocarrier technologies studied, liposomes and gold nanocarriers account for 45% of the total addressable market. Liposomes will offer the largest addressable market ($15 billion) in 2021 while gold nanocarriers will see the highest compound annual growth rate (CAGR)—53.8%—in the next decade.

Drugs are loaded into nanocarriers (also called nanoshells or nanoparticles, between 1 and 100 nm), then transported through the body to the target site. This kind of targeted drug delivery for the treatment of cancers is one of the most anticipated and discussed benefits of nanotechnology-enabled medicine as it offers a level of accuracy in delivering drugs that far surpasses present methods. Typically over 90% of a drug is wasted in the body, which leads to unwanted side effects. Modern chemotherapy bombards patients with drugs in the hope that tumorous cells will be destroyed. The lack of specificity of current drug delivery techniques mean patients' healthy cells are destroyed indiscriminately along with cancer cells.

Using nanotechnology to combat cancer is not new. Abraxane, the first nanoparticulate drug delivery product for the treatment of breast cancer, launched six years ago. There are now hundreds of new nanotech-based treatments under development, ranging from reformulation of existing drugs to enhance their efficacy to radical new "magic bullet" therapies.

The healthcare market is changing. We are seeing a paradigm shift away from blockbusters and a 'one-size fits all' approach to a more personalised medicine based on an individual's unique genome and immune response. The more scientists learn about the molecular causes for disease the more targeted and effective nanotechnology-enabled drug delivery therapies will become.

Table of ContentsTABLE OF EXHIBITS 7

EXECUTIVE SUMMARY 12

CHAPTER 1 - INTRODUCTION 17REPORT SCOPE 17

METHODOLOGY 18

Procurement 18

Calculation of CAGR 19

THE NANOSCALE 20

Two biological examples that illustrate nanoscale: 20

CHAPTER 2 – NANOTECHNOLOGY IN MEDICINE AND BIOMEDICINE 22OVERVIEW OF NANOTECHNOLOGY IN MEDICINE AND BIOMEDICINE 22

Why is Nanotechnology A Critical Application for Medicine and Biomedicine? 22

Why Nanotechnology Is Needed for Medicine and Biomedicine 24

WHAT ARE THE KEY DRIVERS FOR ADOPTION OF NANOTECHNOLOGY IN MEDICINE AND

BIOMEDICINE? 27

The Aim Of Drug Targeting 27

Rapid Market Growth 28

Market Drivers For Enhanced Drug Delivery 28

Increasing Proportion of The Ageing Population 29

Demand For More Affordable Health Care 31

Public Health – Ending disease 31

Demand for More Innovation 31

Social responsibility 31

THE KEY APPLICATIONS OF NANOTECHNOLOGY IN MEDICINE AND BIOMEDICINE 32

How Nanotechnology Can Benefit Drug Delivery 33

Nanotechnology in Medical and Biomedical Diagnostics 34

Nanotechnology in Regenerative Medicine and Tissue Engineering 34

Other Applications For Nanomaterials In The Medical And Pharmaceutical Sector 34

PROMISING EXAMPLES OF NANOTECHNOLOGY ENABLED DRUG DELIVERY 35

Case Study 1 – Magnetic Field Acts as "Remote Control" to Deliver Nanomedicine 35

Case Study 2 - Adaptive Micro and Nanoparticles: Temporal Control Over Carrier

Properties to Facilitate Drug Delivery 36

Case Study 3 – Fabrication of a Nanocarrier System Through Self-Assembly of Plasma

Protein And Its Tumour Targeting 39

Case Study 4 – IBM And The Institute of Bioengineering And Nanotechnology Find

Breakthrough For MRSA 39

CHAPTER 3 – RISK & REGULATION 43THREE KEY BARRIERS TO THE ADOPTION OF NANOTECHNOLOGY IN MEDICINE AND

BIOMEDICINE 43

Nanotoxicity Nanopollution and Nanosafety 43

Ethical Considerations Of Nanotherapies 45

Delayed Nanoregulation 46

FIVE CURRENT & FUTURE CHALLENGES IN THE ADOPTION OF NANOTECHNOLOGY IN

MEDICINE AND BIOMEDICINE 48

Current & Future Challenges of Nanosafety And Risk Management 48

Current & Future Challenges of Nanoregulation 51

Current & Future Challenges for the Nanomedicine Industry 53

Current & Future Challenges of Sustained Innovation 54

Current & Future Challenges of Cooperation 54

CHAPTER 4 – MARKET FOR NANOCARRIERS 57GLOBAL MARKET ANALYSIS: 2000-2010 (WITHOUT SEGMENTATION) 57

GLOBAL MARKET FORECAST: 2011-2021 (WITHOUT SEGMENTATION) 60

DISCUSSION OF NANOPARTICLES & NANOCARRIERS 63

Overview of The Key Nanotechnologies Used in Drug Delivery Sorted by Applications 63

Nanopharmaceuticals 63

Nanotechnology In Drug Delivery 63

Nanobiotechnology In Drug Delivery 64

Analytical Techniques For Nanoparticle Drug Delivery 65

Properties 65

Production of Nanoparticles 65

Measuring Dispersion of Nanoparticles 66

Characterisation of Carrier Systems 67

Nanocarriers 68

Classification of Nanocarriers 68

Multifunctional Nanocarriers - Drug Delivery And Medical / Biomedical Diagnostics 69

Nanocarriers as Drug Carriers 69

What Can Nanoparticles do in Drug Delivery? 69

Polymer-Based Nanocarriers (Polymeric Nanoparticles) 73

Lipid-Based Nanocarriers 75

Organic Nanocarriers 78

Inorganic Nanocarriers 78

Disadvantages Associated With Nanocarriers 79

The Most Relevant Technologies in The Key Area of Nanotechnology in Drug Delivery 80

Stage of Development of Key Nanotechnologies Used in Drug Delivery 80

Clinically Approved Nanocarrier-Based Drug Formulations With Presence on The Market

The First Nanoparticle Drug Delivery System Reaches The Market 81

Present And Future Applications 84

TECHNOLOGY ADOPTION ROADMAP 86

Projected Product Pipeline For Nanocarrier-Based Drug Formulations In Drug Delivery

Market 86

Available Applications Of Nanoparticles In Drug Delivery 87

Semapimod® (cytokine, pharmasciences) 89

Paxceed™ 89

Theralux™ 90

Nucryst® 90

iSPERSE™ 91

ANALYSIS OF TAM FOR NANOCARRIERS: 2000-2010 93

TAM FORECAST FOR NANOCARRIERS: 2011-2021 99

APPENDIX 108

PUBLISHING ACTIVITY BY ORGANIZATION (2000-2010) 108

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Nicolas Bombourg
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Nanotechnology for Drug Delivery : Global Market for Nanocarriers