A new type of micromotor has been developed. Directed by magnets and powered by ultrasound, these micromotors are capable of traveling across microscopic particles and cells in very crowded areas without causing any damage.
These microswimmers provide a new way to manipulate single particles with precise control and in three dimensions, without having to do special sample preparation, labeling, surface modification, said Joseph Wang, a professor of nanoengineering at University of California San Diego (USCD), in a UCSD press release.
Wang, Thomas Mallouk, a professor of chemistry at the University of Pennsylvania, and Wei Wang, professor of materials science and engineering at Harbin Institute of Technology, are credited as senior authors of a paper detailing the development of these micromotors. The study was published on Oct. 25 in Science Advances.
Researchers tested the technology by moving HeLa cells the oldest and most commonly used cell line for scientific research and silica particles in aqueous media with micromotors. They accomplished this task without damaging nearby particles and cells. In one test, the researchers were able to create letters by pushing particles with the micromotors. In another, they exerted control over the micromotors, making them climb up microscopic blocks and stairs. This test demonstrated that they were capable of navigating over three-dimensional objects.
The micromotors are essentially gold-coated hollow polymer structures that are shaped like a half capsule. Within the body of the micromotor is a tiny magnetic nickel nanoparticle, allowing them to be steered with magnets. The inside surface is treated so it can repel water, so when the micromotor is submerged in water, an air bubble is trapped inside the device. This trapped bubble is integral to the functioning of the micromotor, as it allows the micromotor to respond to ultrasound. Upon receiving ultrasound waves, the trapped bubble begins to oscillate, forming forces that give it an initial push to movement. By applying an external magnetic field, it can move continuously, while altering the direction of the field allows researchers to control the speed and trajectory of the micromotors.
We have a lot of control over the motion, unlike a chemically fueled micromotor that relies on random motion to reach its target, said Fernando Soto, a nanoengineering Ph.D. student studying at UC San Diego. Also, ultrasound and magnets are biocompatible, making this micromotor system attractive for use in biological applications.
The authors plan on making improvements to the micromotors in the coming years. For example, they want to make them more biocompatible using biodegradable polymers and a magnetic material that is less toxic, such as iron oxide. Thanks to this technology, the researchers have opened new possibilities for nanomedicine, tissue engineering, targeted drug delivery, regenerative medicine, and other applications in the field of biochemistry.
Read more:
Micromotors move single cells using magnets and ultrasound - CMU The Tartan Online
- Advances in nanotechnology's fight against cancer [Last Updated On: December 27th, 2013] [Originally Added On: December 27th, 2013]
- Nanotechnology and Medicine - Nanomedicine and Disease ... [Last Updated On: December 27th, 2013] [Originally Added On: December 27th, 2013]
- Nanomedicine: Nanotechnology, Biology and Medicine - Official Site [Last Updated On: December 27th, 2013] [Originally Added On: December 27th, 2013]
- Nanomedicine Fact Sheet [Last Updated On: December 27th, 2013] [Originally Added On: December 27th, 2013]
- Nanomedicine, bionanotechnology | NanomedicineCenter.com [Last Updated On: December 27th, 2013] [Originally Added On: December 27th, 2013]
- Nanomedicine - Wikipedia, the free encyclopedia [Last Updated On: December 27th, 2013] [Originally Added On: December 27th, 2013]
- Nanomedicine for drug delivery - Srinivas Sridhar - Video [Last Updated On: December 28th, 2013] [Originally Added On: December 28th, 2013]
- IT-CRS 2013 workshop- Prof. Kevin Breackmans. Studying nanomedicine biobarriers - Video [Last Updated On: December 30th, 2013] [Originally Added On: December 30th, 2013]
- Nanotechnology in Medicine - UnderstandingNano [Last Updated On: January 3rd, 2014] [Originally Added On: January 3rd, 2014]
- Nanomedicine - Nanorobots in Medicine - UnderstandingNano [Last Updated On: January 8th, 2014] [Originally Added On: January 8th, 2014]
- Nanomedicine: Challenges and opportunities - Video [Last Updated On: January 13th, 2014] [Originally Added On: January 13th, 2014]
- Global Nanomedicine Market is Expected to Reach USD 177.60 Billion in 2019: Transparency Market Research [Last Updated On: January 16th, 2014] [Originally Added On: January 16th, 2014]
- NANOMEDICINE 1 - Video [Last Updated On: January 17th, 2014] [Originally Added On: January 17th, 2014]
- Researchers measure minuscule particles with 'tiny diving boards' [Last Updated On: January 20th, 2014] [Originally Added On: January 20th, 2014]
- High Unmet Needs in Therapeutics to Spur Growth in the Market for Nanotechnology in Drug Delivery, According to New ... [Last Updated On: January 21st, 2014] [Originally Added On: January 21st, 2014]
- Nanomedicine Market - Video [Last Updated On: January 22nd, 2014] [Originally Added On: January 22nd, 2014]
- Nanomedicine and human upper limit - Video [Last Updated On: January 23rd, 2014] [Originally Added On: January 23rd, 2014]
- Animated Nanomedicine movie - Video [Last Updated On: February 2nd, 2014] [Originally Added On: February 2nd, 2014]
- In Vitro Innovation: Testing Nanomedicine With Blood Cells On A Microchip [Last Updated On: February 4th, 2014] [Originally Added On: February 4th, 2014]
- Nanomedicine Market is Expected to Reach USD 177.60 Billion in 2019 [Last Updated On: February 7th, 2014] [Originally Added On: February 7th, 2014]
- NANOMEDICINE 4: AYDEN JACOB FROM UCSF - Video [Last Updated On: February 7th, 2014] [Originally Added On: February 7th, 2014]
- New Live-Cell Printing Technology Works Like Ancient Chinese Woodblocking [Last Updated On: February 10th, 2014] [Originally Added On: February 10th, 2014]
- NANOMEDICINE HANGOUT: ARSALAN SHABBIR MD - Video [Last Updated On: February 14th, 2014] [Originally Added On: February 14th, 2014]
- Using Mathematical Models to Understand Nanoscale Roughness Published by Dove Medical Press [Last Updated On: February 17th, 2014] [Originally Added On: February 17th, 2014]
- NTU and Northwestern University to set up $70 million nanomedicine research institute [Last Updated On: February 20th, 2014] [Originally Added On: February 20th, 2014]
- Interview with Medical Animator YURIY SVIDINENKO, about Nanotechnology Videos - Video [Last Updated On: February 21st, 2014] [Originally Added On: February 21st, 2014]
- TTU MSE nanomedicine lab NML 2013 f - Video [Last Updated On: February 21st, 2014] [Originally Added On: February 21st, 2014]
- Nanomedicine Vietsubtitles - Video [Last Updated On: February 24th, 2014] [Originally Added On: February 24th, 2014]
- Biochips for Better Cancer Therapy in NanoMedicine - Video [Last Updated On: February 27th, 2014] [Originally Added On: February 27th, 2014]
- 13 Nanomedicine Part 1 - Video [Last Updated On: February 28th, 2014] [Originally Added On: February 28th, 2014]
- 13 Nanomedicine part 2 - Video [Last Updated On: February 28th, 2014] [Originally Added On: February 28th, 2014]
- practicum nanomedicine pws Nicole en jordy - Video [Last Updated On: March 6th, 2014] [Originally Added On: March 6th, 2014]
- Nanomedicine, Detto tra Noi, 4 marzo 2014 - Video [Last Updated On: March 6th, 2014] [Originally Added On: March 6th, 2014]
- Brown Symposium XXXVI - Mauro Ferrari: "Nanomedicine and New Societal Horizons" - Video [Last Updated On: March 9th, 2014] [Originally Added On: March 9th, 2014]
- nanomedicine nanobiotix itele - Video [Last Updated On: March 9th, 2014] [Originally Added On: March 9th, 2014]
- NANOMEDICINE HANGOUT UNIVERSITY OF MIAMI ARSALAN SHABBIR MD - Video [Last Updated On: March 16th, 2014] [Originally Added On: March 16th, 2014]
- NANOMEDICINE HANGOUT1 - Video [Last Updated On: March 21st, 2014] [Originally Added On: March 21st, 2014]
- NANOMEDICINE HANGOUT - Video [Last Updated On: March 21st, 2014] [Originally Added On: March 21st, 2014]
- Ideas @Davos | Sonia Trigueros | Breakthroughs in Nanomedicine - Video [Last Updated On: March 22nd, 2014] [Originally Added On: March 22nd, 2014]
- Nanomedicine: towards development of patient-friendly drug-delivery systems - Video [Last Updated On: March 23rd, 2014] [Originally Added On: March 23rd, 2014]
- Nanomedicine Research [Last Updated On: March 26th, 2014] [Originally Added On: March 26th, 2014]
- Nanomedicinecenter.com - Nanomedicine, bionanotechnology ... [Last Updated On: August 18th, 2024] [Originally Added On: March 26th, 2014]
- Nanomedicine, Volume 1: Basic Capabilities [Last Updated On: August 18th, 2024] [Originally Added On: March 26th, 2014]
- Nanomedicine: towards development of patient-friendly drug-delivery systems - Video [Last Updated On: August 18th, 2024] [Originally Added On: March 26th, 2014]
- Ideas @Davos | Sonia Trigueros | Breakthroughs in Nanomedicine - Video [Last Updated On: August 18th, 2024] [Originally Added On: March 26th, 2014]
- NANOMEDICINE HANGOUT1 - Video [Last Updated On: August 18th, 2024] [Originally Added On: March 26th, 2014]
- NANOMEDICINE HANGOUT - Video [Last Updated On: August 18th, 2024] [Originally Added On: March 26th, 2014]
- Mining Genome Information for New Starting Points in Personalized Cancer Nanomedicine - Video [Last Updated On: August 18th, 2024] [Originally Added On: March 27th, 2014]
- Mining Genome Information for New Starting Points in Personalized Cancer Nanomedicine - Video [Last Updated On: March 28th, 2014] [Originally Added On: March 28th, 2014]
- Cancer Stem Cells as Preferential Target for Personalized Cancer Nanomedicine - Video [Last Updated On: March 28th, 2014] [Originally Added On: March 28th, 2014]
- Nanomedicine Against Malaria: Use of Poly-based Nanovectors for the Drug Delivery to Plasmodium - Video [Last Updated On: August 18th, 2024] [Originally Added On: March 29th, 2014]
- Panel - The Horizon of Nanomedicine and Targeted Drug Delivery - Video [Last Updated On: August 18th, 2024] [Originally Added On: March 29th, 2014]
- Panel - The Regulation Environment in Nanomedicine -- The Step to the Last Phase of Translation - Video [Last Updated On: August 18th, 2024] [Originally Added On: March 29th, 2014]
- Cancer Stem Cells as Preferential Target for Personalized Cancer Nanomedicine - Video [Last Updated On: August 18th, 2024] [Originally Added On: March 29th, 2014]
- Nanomedicine Against Malaria: Use of Poly-based Nanovectors for the Drug Delivery to Plasmodium - Video [Last Updated On: March 29th, 2014] [Originally Added On: March 29th, 2014]
- Panel - The Horizon of Nanomedicine and Targeted Drug Delivery - Video [Last Updated On: March 29th, 2014] [Originally Added On: March 29th, 2014]
- Panel - The Regulation Environment in Nanomedicine -- The Step to the Last Phase of Translation - Video [Last Updated On: March 29th, 2014] [Originally Added On: March 29th, 2014]
- Looking and Listening to Light from Liposome Nanostructures for Cancer Theranostics - Video [Last Updated On: March 29th, 2014] [Originally Added On: March 29th, 2014]
- Looking and Listening to Light from Liposome Nanostructures for Cancer Theranostics - Video [Last Updated On: August 18th, 2024] [Originally Added On: March 30th, 2014]
- NANOMEDICINE 3 Quantum Dot Technology for Multiplexing Applications# - Video [Last Updated On: August 18th, 2024] [Originally Added On: March 31st, 2014]
- Nanobiotix Selected to Present Data from NBTXR3 Clinical Trial at the 50th Annual Meeting of the American Society of ... [Last Updated On: April 2nd, 2014] [Originally Added On: April 2nd, 2014]
- OMICS Groups Nanotechnology International Conference to Challenge the Old Frontiers [Last Updated On: August 18th, 2024] [Originally Added On: April 3rd, 2014]
- Nanobiotix Selected to Present Data from NBTXR3 Clinical Trial at the 50th Annual Meeting of the American Society of ... [Last Updated On: August 18th, 2024] [Originally Added On: April 3rd, 2014]
- Breakthroughs in Nanomedicine-A World Economic Forum Discussion-Ideas @Davos-WIRED - Video [Last Updated On: April 4th, 2014] [Originally Added On: April 4th, 2014]
- How IBM Is Using Nanotechnology To Tackle MRSA And HIV [Last Updated On: August 18th, 2024] [Originally Added On: April 4th, 2014]
- How IBM Is Using Nanotechnology To Tackle MRSA And HIV [Last Updated On: April 5th, 2014] [Originally Added On: April 5th, 2014]
- In latest generation of tiny biosensors, size isn't everything [Last Updated On: April 14th, 2014] [Originally Added On: April 14th, 2014]
- In latest generation of tiny biosensors, size isn't everything [Last Updated On: August 18th, 2024] [Originally Added On: April 14th, 2014]
- Nanomedicine Research [Last Updated On: August 18th, 2024] [Originally Added On: April 14th, 2014]
- Nanomedicine Market (Neurology, Cardiovascular, Anti-inflammatory, Anti-infective, and Oncology Applications) - Global ... [Last Updated On: April 17th, 2014] [Originally Added On: April 17th, 2014]
- Nanomedicine Market (Neurology, Cardiovascular, Anti-inflammatory, Anti-infective, and Oncology Applications) - Global ... [Last Updated On: August 18th, 2024] [Originally Added On: April 18th, 2014]
- doctors-hospital-surgery-AFprelax-210414.jpg [Last Updated On: April 21st, 2014] [Originally Added On: April 21st, 2014]
- Nanomedicine - Video [Last Updated On: April 25th, 2014] [Originally Added On: April 25th, 2014]
- Nanomedicine - Video [Last Updated On: August 18th, 2024] [Originally Added On: April 25th, 2014]
- Nanomedicine Presentation - Video [Last Updated On: May 6th, 2014] [Originally Added On: May 6th, 2014]
- Nanomedicine Promo - Video [Last Updated On: May 6th, 2014] [Originally Added On: May 6th, 2014]
- Nanomedicine Presentation - Video [Last Updated On: August 18th, 2024] [Originally Added On: May 6th, 2014]
- Nanomedicine Promo - Video [Last Updated On: August 18th, 2024] [Originally Added On: May 6th, 2014]
- A skinful of nanoparticles starts to show [Last Updated On: May 16th, 2014] [Originally Added On: May 16th, 2014]
- nanomedicine edit1 - Video [Last Updated On: May 17th, 2014] [Originally Added On: May 17th, 2014]