Main article: Mind uploading

Mind uploading, mind transfer or whole brain emulation is a use of a computer as an emulated human brain, and the view of thoughts and memories as software information states. The term mind transfer also refers to a hypothetical transfer of a mind from one biological brain to another. It is a common theme in science fiction.

One of the earliest examples can be found in Frederik Pohl's story "The Tunnel Under the World" from 1955. In this story, the protagonist Guy Burckhardt continually wakes up on the same date from a dream of dying in an explosion. Burckhardt is already familiar with the idea of putting human minds in robotic bodies, since this is what is done with the robot workers at the nearby Contro Chemical factory. As someone has once explained it to him, "each machine was controlled by a sort of computer which reproduced, in its electronic snarl, the actual memory and mind of a human being ... It was only a matter, he said, of transferring a man's habit patterns from brain cells to vacuum-tube cells." Later in the story, Pohl gives some additional description of the procedure: "Take a master petroleum chemist, infinitely skilled in the separation of crude oil into its fractions. Strap him down, probe into his brain with searching electronic needles. The machine scans the patterns of the mind, translates what it sees into charts and sine waves. Impress these same waves on a robot computer and you have your chemist. Or a thousand copies of your chemist, if you wish, with all of his knowledge and skill, and no human limitations at all." After some investigation, Burckhardt learns that his entire town had been killed in a chemical explosion, and the brains of the dead townspeople had been scanned and placed into miniature robotic bodies in a miniature replica of the town (as a character explains to him, 'It's as easy to transfer a pattern from a dead brain as a living one'), so that a businessman named Mr. Dorchin could charge companies to use the townspeople as test subjects for new products and advertisements.

Something close to the notion of mind uploading is very briefly mentioned in Isaac Asimov's 1956 short story The Last Question: "One by one Man fused with AC, each physical body losing its mental identity in a manner that was somehow not a loss but a gain." A more detailed exploration of the idea (and one in which individual identity is preserved, unlike in Asimov's story) can be found in ArthurC. Clarke's novel The City and the Stars, also from 1956 (this novel was a revised and expanded version of Clarke's earlier story Against the Fall of Night, but the earlier version did not contain the elements relating to mind uploading). The story is set in a city named Diaspar one billion years in the future, where the minds of inhabitants are stored as patterns of information in the city's Central Computer in between a series of 1000-year lives in cloned bodies. Various commentators identify this story as one of the first (if not the first) to deal with mind uploading, human-machine synthesis, and computerized immortality.[1][2][3][4]

Another of the "firsts" is the novel Detta r verkligheten (This is reality), 1968, by the renowned philosopher and logician Bertil Mrtensson, a novel in which he describes people living in an uploaded state as a means to control overpopulation. The uploaded people believe that they are "alive", but in reality they are playing elaborate and advanced fantasy games. In a twist at the end, the author changes everything into one of the best "multiverse" ideas of science fiction.

In Robert Silverberg's To Live Again (1969), an entire worldwide economy is built up around the buying and selling of "souls" (personas that have been tape-recorded at six-month intervals), allowing well-heeled consumers the opportunity to spend tens of millions of dollars on a medical treatment that uploads the most recent recordings of archived personalities into the minds of the buyers. Federal law prevents people from buying a "personality recording" unless the possessor first had died; similarly, two or more buyers were not allowed to own a "share" of the persona. In this novel, the personality recording always went to the highest bidder. However, when one attempted to buy (and therefore possess) too many personalities, there was the risk that one of the personas would wrest control of the body from the possessor.

In the 1982 novel Software, part of the Ware Tetralogy by Rudy Rucker, one of the main characters, Cobb Anderson, has his mind downloaded and his body replaced with an extremely human-like android body. The robots who persuade Anderson into doing this sell the process to him as a way to become immortal.

In William Gibson's award-winning Neuromancer (1984), which popularized the concept of "cyberspace", a hacking tool used by the main character is an artificial infomorph of a notorious cyber-criminal, Dixie Flatline. The infomorph only assists in exchange for the promise that he be deleted after the mission is complete.

The fiction of Greg Egan has explored many of the philosophical, ethical, legal, and identity aspects of mind transfer, as well as the financial and computing aspects (i.e. hardware, software, processing power) of maintaining "copies." In Egan's Permutation City (1994), Diaspora (1997) and Zendegi (2010), "copies" are made by computer simulation of scanned brain physiology. See also Egan's "jewelhead" stories, where the mind is transferred from the organic brain to a small, immortal backup computer at the base of the skull, the organic brain then being surgically removed.

The movie The Matrix is commonly mistaken for a mind uploading movie, but is only about virtual reality and simulated reality, since the main character Neo's physical brain still is required to reside his mind. The mind (the information content of the brain) is not copied into an emulated brain in a computer. Neo's physical brain is connected into the Matrix via a brain-machine interface. Only the rest of the physical body is simulated. Neo is disconnected from and reconnected to this dreamworld.

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