There’s always something interesting in the news when it comes to progress in regenerative medicine and tissue engineering. This is the sort of research community we want to see for every field that might impact human aging and longevity: large, thriving, dynamic, and attracting plenty of attention and funding. The practical result is that we live in exciting times – organ regrowth is right around the corner, as is the prospect of meaningful repair or replacement of many types of aged tissue. Regenerative medicine is not a one-stop solution for all of aging, but it is one of the necessary pillars of the true rejuvenation biotechnology that will be developed in the decades to come.
Here are a few articles that caught my eye of late; the mainstream media seems to be picking up the level of attention they are giving to the cutting edge of regenerative medicine these days.
Seeing local scientists at heart of regenerative medicine
In one lab, a surgeon builds a pink, pulsing heart, cell by cell. In another, a researcher literally sprays new skin onto severely burned patients. Elsewhere, a scientist re-creates the delicate folds of the ear – on the back of a mouse. Sound like science fiction? It already is science: Researchers in Boston and beyond are building everything from blood vessels to internal organs, using engineering tricks and dome-like bioreactors. Tonight, in ‘How to Build a Beating Heart,’ National Geographic Explorer investigates those efforts to transform human health, revealing the pulse-quickeningly cool side of regenerative medicine.
Building body parts: Saving lives, salamander style
If an injured salamander can grow a new limb, why can’t a human? Maybe they can, say researchers at the Armed Forces Institute of Regenerative Medicine. Starting with stem cells from patient’s bodies, scientists at this Wake Forest University facility have grown 22 different types of tissues and organs. Lives are being saved and more amazing successes are on the way.
Skin cells help to develop possible heart defect treatment in first-of-its-kind Stanford study
Using skin cells from young patients who have a severe genetic heart defect, Stanford University School of Medicine scientists have generated beating heart cells that carry the same genetic mutation. The newly created human heart cells – cardiomyocytes – allowed the researchers for the first time to examine and characterize the disorder at the cellular level. … the investigators also report their identification of a promising drug to reverse the heart malfunction – for which there are currently no decent treatments – after using these newly created heart cells to check the effects of a plethora of compounds.
College of Veterinary Medicine to perform an animal stem cell first
The first animal stem cell procedure in Oregon done entirely in a veterinary facility is scheduled for Thursday at the Oregon State University College of Veterinary Medicine. The procedure will be performed on Basco (pronounced “Bosco”), a 7-year-old German Shepherd suffering from osteoarthritis in his left rear hip. … Fat tissue is removed from the animal, the stem cells are separated and activated, and then injected into the affected area. Within three to four weeks of the procedure, Basco should be moving well, with little or no pain, Medi-Vet predicted.
Veterinary medicine is far ahead in its application of first generation stem cell therapies; if you’re a human in need of the same sort of treatment, you’ll have to leave the US to find it. The principle effect of heavy US regulations on medical development is to ensure that working, beneficial, reasonably safe treatments take a very long time to come to the clinic and are very expensive when they arrive. Fortunately the FDA can’t do anything about the competitive service providers and medical research and development groups in other parts of the world. Thus, absent a sea change in the state of regulation in the US, medical tourism will be a part of all our futures, and we will benefit greatly from the fact that at least some parts of the world are not as shackled and held back by a full-on command economy medical system.
- Vitamin K Delivers Kick to Cancer Risk [Last Updated On: August 17th, 2024] [Originally Added On: April 7th, 2010]
- Magnesium for Memory [Last Updated On: August 17th, 2024] [Originally Added On: April 7th, 2010]
- The Long Road Towards Prosthetic Nerves [Last Updated On: August 17th, 2024] [Originally Added On: April 9th, 2010]
- More on DAF-16 and Longevity in Nematodes [Last Updated On: August 17th, 2024] [Originally Added On: April 9th, 2010]
- Rapamycin and Alzheimer's Disease [Last Updated On: August 17th, 2024] [Originally Added On: April 9th, 2010]
- Rapamycin and Alzheimer's Disease [Last Updated On: August 17th, 2024] [Originally Added On: April 9th, 2010]
- Better Understanding Cytomegalovirus [Last Updated On: August 17th, 2024] [Originally Added On: April 9th, 2010]
- On Mitophagy and Aging [Last Updated On: August 17th, 2024] [Originally Added On: April 9th, 2010]
- A Trial of Giving Stem Cells Orders [Last Updated On: August 17th, 2024] [Originally Added On: April 9th, 2010]
- Methuselah Foundation Launches NewOrgan Prize [Last Updated On: August 17th, 2024] [Originally Added On: April 9th, 2010]
- The Contributions of Mitochondria to Longevity [Last Updated On: August 17th, 2024] [Originally Added On: April 9th, 2010]
- Dual Action Antibodies Versus Cancer [Last Updated On: August 17th, 2024] [Originally Added On: April 9th, 2010]
- Longevity and the End of Empire [Last Updated On: August 17th, 2024] [Originally Added On: April 9th, 2010]
- The Long Road Towards Prosthetic Nerves [Last Updated On: August 17th, 2024] [Originally Added On: April 10th, 2010]
- More on DAF-16 and Longevity in Nematodes [Last Updated On: August 17th, 2024] [Originally Added On: April 10th, 2010]
- Rapamycin and Alzheimer’s Disease [Last Updated On: August 17th, 2024] [Originally Added On: April 10th, 2010]
- Better Understanding Cytomegalovirus [Last Updated On: August 17th, 2024] [Originally Added On: April 10th, 2010]
- On Mitophagy and Aging [Last Updated On: August 17th, 2024] [Originally Added On: April 10th, 2010]
- A Trial of Giving Stem Cells Orders [Last Updated On: August 17th, 2024] [Originally Added On: April 10th, 2010]
- Methuselah Foundation Launches NewOrgan Prize [Last Updated On: August 17th, 2024] [Originally Added On: April 10th, 2010]
- The Contributions of Mitochondria to Longevity [Last Updated On: August 17th, 2024] [Originally Added On: April 10th, 2010]
- Dual Action Antibodies Versus Cancer [Last Updated On: August 17th, 2024] [Originally Added On: April 10th, 2010]
- Longevity and the End of Empire [Last Updated On: August 17th, 2024] [Originally Added On: April 10th, 2010]
- Longevity Meme Newsletter, April 12 2010 [Last Updated On: August 17th, 2024] [Originally Added On: April 12th, 2010]
- Printing New Tissue Directly Onto the Body [Last Updated On: August 17th, 2024] [Originally Added On: April 12th, 2010]
- Reprogramming Autoimmune Disease [Last Updated On: August 17th, 2024] [Originally Added On: April 12th, 2010]
- Diet and Exercise Can Override the Genetic Disposition towards Obesity [Last Updated On: August 17th, 2024] [Originally Added On: April 12th, 2010]
- Your Heart Truly Loves Chocolate! [Last Updated On: August 17th, 2024] [Originally Added On: April 12th, 2010]
- CSC news roundup 2010-04-11 [Last Updated On: August 17th, 2024] [Originally Added On: April 13th, 2010]
- Longevity Meme Newsletter, April 12 2010 [Last Updated On: August 17th, 2024] [Originally Added On: April 13th, 2010]
- Printing New Tissue Directly Onto the Body [Last Updated On: August 17th, 2024] [Originally Added On: April 13th, 2010]
- Reprogramming Autoimmune Disease [Last Updated On: August 17th, 2024] [Originally Added On: April 13th, 2010]
- Diet and Exercise Can Override the Genetic Disposition towards Obesity [Last Updated On: August 17th, 2024] [Originally Added On: April 13th, 2010]
- Your Heart Truly Loves Chocolate! [Last Updated On: August 17th, 2024] [Originally Added On: April 13th, 2010]
- Trialing Stem Cells to Heal Heart Damage [Last Updated On: August 17th, 2024] [Originally Added On: April 13th, 2010]
- Selection Effects and Longevity Genes [Last Updated On: August 17th, 2024] [Originally Added On: April 13th, 2010]
- How Exercise Can Awaken Your Creative Genius Within [Last Updated On: August 17th, 2024] [Originally Added On: April 13th, 2010]
- Trialing Stem Cells to Heal Heart Damage [Last Updated On: August 17th, 2024] [Originally Added On: April 14th, 2010]
- Selection Effects and Longevity Genes [Last Updated On: August 17th, 2024] [Originally Added On: April 14th, 2010]
- How Exercise Can Awaken Your Creative Genius Within [Last Updated On: August 17th, 2024] [Originally Added On: April 14th, 2010]
- WILT, ALT, and Zscan4 [Last Updated On: August 17th, 2024] [Originally Added On: April 14th, 2010]
- Damage in Early Life Shortens Life Expectancy [Last Updated On: August 17th, 2024] [Originally Added On: April 14th, 2010]
- WILT, ALT, and Zscan4 [Last Updated On: August 17th, 2024] [Originally Added On: April 15th, 2010]
- Damage in Early Life Shortens Life Expectancy [Last Updated On: August 17th, 2024] [Originally Added On: April 15th, 2010]
- Synthetic Biology and the Extracellular Matrix [Last Updated On: August 17th, 2024] [Originally Added On: April 15th, 2010]
- The Tithonus Error as Prospection Error [Last Updated On: August 17th, 2024] [Originally Added On: April 15th, 2010]
- F.D.A. Says Millions Got Unapproved Drugs, Should the new bioequivalence and bioanalytical guidelines for 2010, be made more stringent [Last Updated On: August 17th, 2024] [Originally Added On: April 16th, 2010]
- Synthetic Biology and the Extracellular Matrix [Last Updated On: August 17th, 2024] [Originally Added On: April 16th, 2010]
- The Tithonus Error as Prospection Error [Last Updated On: August 17th, 2024] [Originally Added On: April 16th, 2010]
- Towards an Artificial Pancreas [Last Updated On: August 17th, 2024] [Originally Added On: April 16th, 2010]
- Immortality Isn't Unethical [Last Updated On: August 17th, 2024] [Originally Added On: April 16th, 2010]
- Immortality Isn't Unethical [Last Updated On: August 17th, 2024] [Originally Added On: April 16th, 2010]
- Alcohol in Adolescence: A Cancerous Combination? [Last Updated On: August 17th, 2024] [Originally Added On: April 16th, 2010]
- Green Tea for Weight Loss [Last Updated On: August 17th, 2024] [Originally Added On: April 16th, 2010]
- Towards an Artificial Pancreas [Last Updated On: August 17th, 2024] [Originally Added On: April 17th, 2010]
- Immortality Isn’t Unethical [Last Updated On: August 17th, 2024] [Originally Added On: April 17th, 2010]
- Alcohol in Adolescence: A Cancerous Combination? [Last Updated On: August 17th, 2024] [Originally Added On: April 17th, 2010]
- Green Tea for Weight Loss [Last Updated On: August 17th, 2024] [Originally Added On: April 17th, 2010]
- On Calorie Restriction Research [Last Updated On: August 17th, 2024] [Originally Added On: April 17th, 2010]
- AGE Precursor Methylglyoxal Also an Issue? [Last Updated On: August 17th, 2024] [Originally Added On: April 17th, 2010]
- On Calorie Restriction Research [Last Updated On: August 17th, 2024] [Originally Added On: April 18th, 2010]
- AGE Precursor Methylglyoxal Also an Issue? [Last Updated On: August 17th, 2024] [Originally Added On: April 18th, 2010]
- Longevity Meme Newsletter, April 19 2010 [Last Updated On: August 17th, 2024] [Originally Added On: April 19th, 2010]
- Let Them Eat Wheat [Last Updated On: August 17th, 2024] [Originally Added On: April 19th, 2010]
- An Appetite for Alzheimer’s Avoidance [Last Updated On: August 17th, 2024] [Originally Added On: April 19th, 2010]
- Steps Towards Controlling Regeneration [Last Updated On: August 17th, 2024] [Originally Added On: April 20th, 2010]
- Another View of What to Do About Aging [Last Updated On: August 17th, 2024] [Originally Added On: April 20th, 2010]
- Rare flowers and common herbal supplements get unmasked with plant DNA barcoding [Last Updated On: August 17th, 2024] [Originally Added On: April 21st, 2010]
- Steps Towards Controlling Regeneration [Last Updated On: August 17th, 2024] [Originally Added On: April 21st, 2010]
- Another View of What to Do About Aging [Last Updated On: August 17th, 2024] [Originally Added On: April 21st, 2010]
- Stopping Metastasis [Last Updated On: August 17th, 2024] [Originally Added On: April 21st, 2010]
- Humanity+ Summit at Harvard [Last Updated On: August 17th, 2024] [Originally Added On: April 21st, 2010]
- Stopping Metastasis [Last Updated On: August 17th, 2024] [Originally Added On: April 22nd, 2010]
- Humanity+ Summit at Harvard [Last Updated On: August 17th, 2024] [Originally Added On: April 22nd, 2010]
- An Update on Scent and Longevity [Last Updated On: August 17th, 2024] [Originally Added On: April 22nd, 2010]
- Tissue Engineered Skin Progresses [Last Updated On: August 17th, 2024] [Originally Added On: April 22nd, 2010]
- Because Someone Has to State the Obvious [Last Updated On: August 17th, 2024] [Originally Added On: April 23rd, 2010]
- Deciphering Regeneration [Last Updated On: August 17th, 2024] [Originally Added On: April 23rd, 2010]
- Politics and Historical Aspirations to Engineered Longevity [Last Updated On: August 17th, 2024] [Originally Added On: April 24th, 2010]
- Exercise and Alzheimer's Disease [Last Updated On: August 17th, 2024] [Originally Added On: April 24th, 2010]