PUBLIC RELEASE DATE:

25-Jun-2014

Contact: Vicki Cohn vcohn@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, June 25, 2014For some children an allergic reaction to common foods such as milk, eggs, or peanuts can cause an anaphylactic reaction. At present no effective treatment for food allergy exists, and strict dietary avoidance of known food triggers is the only preventive option available. Ongoing trials are exploring options for oral immunotherapy (OIT) for desensitization in the treatment of Immunoglobulin E (IgE)-mediated food allergy, as described in a Review article in Pediatric Allergy, Immunology, and Pulmonology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Pediatric Allergy, Immunology, and Pulmonology website.

In "Oral Immunotherapy for Treatment of Immunoglobulin E-Mediated Food Allergy: The Transition to Clinical Practice," Giovanni Pajno, MD and coauthors, University of Messina, Italy and Nova Southeastern University, Fort Lauderdale, FL, review the current state of OIT research for the induction of tolerance in individuals with food allergies. While early trials with OIT appear promising, rigorous, multicenter, randomized, placebo-controlled studies are needed to address remaining questions regarding optimal formulation, dosing, and duration for the induction of tolerance in affected patients.

"Oral immunotherapy for the treatment of IgE-mediated food allergy remains experimental with a number of unanswered questions," says Editor-in-Chief Mary Cataletto, MD, Professor of Clinical Pediatrics, State University of New York at Stony Brook (Stony Brook, NY) and practicing pediatric pulmonologist at Winthrop University Hospital. "However, it offers the potential for not only a life-saving but life-changing therapy for individuals with food allergies."

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About the Journal

Pediatric Allergy, Immunology, and Pulmonology is a quarterly peer-reviewed journal published in online with Open Access options and in print. The Journal synthesizes the pulmonary, allergy, and immunology communities in the advancement of the respiratory health of children. The Journal provides comprehensive coverage to further the understanding, and optimize the treatment, of some of the most common and costly chronic illnesses in children. It includes original translational, clinical, and epidemiologic research; public health, quality improvement, and case control studies; patient education research; and the latest research and standards of care for functional and genetic immune deficiencies and interstitial lung diseases. Tables of content and a sample issue may be viewed on the Pediatric Allergy, Immunology, and Pulmonology website.

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New treatment option in development for individuals with food allergy