EAST HANOVER, N.J.--(BUSINESS WIRE)--Immetas Therapeutics today announced it has raised a Series A financing of $11 million to advance research on inflammation pathways in aging and the development of novel, immune modulating treatments for cancer and inflammatory disease. Morningside Ventures was the sole investor in the financing round.
Morningsides investment is a significant endorsement of our approach to targeting inflammation pathways in aging and our clinical evidence-based discovery strategy, said J. Gene Wang, MD, PhD, co-founder and CEO. Emerging research that molecular pathways driving both aging and age-related diseases converge around chronic, low grade inflammation is creating a new set of opportunities to treat cancer and other serious diseases. Immetas is well positioned to capitalize on these new advances.
Dr. Wang added, Our approach prioritizes clinical evidence and a deep interrogation of disease mechanisms to guide drug discovery. This strategy is designed to reduce development risk resulting from the translational gap between laboratory findings and patients and ensure the development of superior and well-differentiated drugs.
Dr. Wang co-founded Immetas after a 20-year career at large pharmaceutical companies, including Merck, Abbott, GSK and Novartis, where he played integral roles in the successful development of major drugs, including Humira (adalimumab), Varubi (rolapitant), Zolinza (vorinostat) and Gardasil (human papilloma virus vaccine), and led multiple programs from discovery to clinical proof-of-concept. Dr. Wang received his M.D. from Peking University Medical Center and Ph.D. in Immunobiology from Yale University, followed by medical residency training at Yale New Haven Hospital.
Immetas other co-founder, Dr. David Sinclair, is an internationally recognized scientist known for his research on genes and small molecules that delay aging, including Sirtuin genes, resveratrol and NAD precursors. He was among TIME magazines 50 Most Influential People in Healthcare in 2018. Dr. Sinclair is Professor of Genetics at Harvard Medical School and co-Director of the Paul F. Glenn Center for Biology of Aging Research at Harvard and he serves as a science advisor to the Company.
We have a shared vision that inflammation is the fundamental and ultimate process driving aging and age-related cancers and inflammatory diseases, said Dr. Sinclair. Our approach is distinct from others that have targeted conventional age-related pathways and to date have proved challenging.
The Company is building a pipeline of biologic and small molecule drugs internally and through collaborations. Immetas lead program is aimed at designing a series of bi-specific antibodies to regulate inflammation in the tumor microenvironment and overcome resistance to conventional immune checkpoint therapies.
In connection with the financing, Dr. Lu Huang, MD, MBA, Managing Director at Morningside Ventures, joined the Immetas board of directors. Since joining Morningside in 2003, Dr. Huang has led nearly three dozen healthcare / life science investments in China and the United States.
About Immetas TherapeuticsImmetas discovers and develops novel therapeutics that modulate the innate immune system to treat age-related cancers and inflammatory diseases. The companys approach is based on emerging evidence that chronic low-grade inflammation is a fundamental process governing aging and age-related diseases and anchored in clinical evidence to mitigate development risk. Immetas was founded by J. Gene Wang, MD, PhD, a veteran in discovery and translational drug development in immunology/ inflammation and oncology, and David Sinclair, PhD, Professor of Genetics at Harvard Medical School and a leader in the molecular mechanisms of aging. The lead program in the companys growing pipeline is focused on engineering bispecific antibodies to modulate inflammation in the tumor microenvironment and overcome resistance to the conventional immune checkpoint therapies. Learn more at http://www.immetas.com
Go here to read the rest:
Immetas Therapeutics Announces Series A Financing to Advance Research on Inflammation Pathways in Aging and Develop Therapeutics for Cancer and...
- Scientists believe that aging might be optional - Mail Herald [Last Updated On: August 18th, 2024] [Originally Added On: November 18th, 2019]
- This Week in Running: November 18, 2019 - iRunFar [Last Updated On: August 18th, 2024] [Originally Added On: November 21st, 2019]
- Aging as a preventable disease and why living to 100 should be easy - Genetic Literacy Project [Last Updated On: August 18th, 2024] [Originally Added On: November 21st, 2019]
- David Sinclair on Joe Rogan Podcast - chatting about NMN and ... [Last Updated On: August 18th, 2024] [Originally Added On: November 23rd, 2019]
- NMN and NAD Reverse Aging of Blood Vessels in New Study [Last Updated On: August 18th, 2024] [Originally Added On: November 23rd, 2019]
- #70 - David Sinclair, Ph.D.: How cellular reprogramming could ... [Last Updated On: August 18th, 2024] [Originally Added On: November 23rd, 2019]
- Lifespan: Why We Age_and Why We Don't Have To: David A ... [Last Updated On: August 18th, 2024] [Originally Added On: November 23rd, 2019]
- David Sinclair supplements and protocol explained NMN ... [Last Updated On: August 18th, 2024] [Originally Added On: November 23rd, 2019]
- David Sinclair's biological age was 58 after taking 1000 mg ... [Last Updated On: August 18th, 2024] [Originally Added On: November 23rd, 2019]
- David Sinclairs anti-aging science | Harvard Magazine [Last Updated On: August 18th, 2024] [Originally Added On: November 23rd, 2019]
- David Sinclair Supplements For Anti-Aging - What He Takes & Why [Last Updated On: August 18th, 2024] [Originally Added On: November 23rd, 2019]
- What Does David Sinclair Eat and Supplement? (2019 ... [Last Updated On: August 18th, 2024] [Originally Added On: November 23rd, 2019]
- #27 - David Sinclair, Ph.D.: Slowing aging sirtuins, NAD ... [Last Updated On: August 18th, 2024] [Originally Added On: November 23rd, 2019]
- Man with string of convictions in his native Poland came to Perth to set up drug den - The Courier [Last Updated On: August 18th, 2024] [Originally Added On: November 30th, 2019]
- Last surviving Viking-inspired boat that served a now- abandoned island goes up for auction - The Scotsman [Last Updated On: August 18th, 2024] [Originally Added On: November 30th, 2019]
- Dealer Jailed After Raid Uncovers 44k of Grugs - Daily Record [Last Updated On: August 18th, 2024] [Originally Added On: November 30th, 2019]
- Lazarus Effect: Sixteen-year study by Dr. Leis resulted in recovery from West Nile for Dr. Bush - Northside Sun [Last Updated On: August 18th, 2024] [Originally Added On: December 21st, 2019]
- OZY Takes You Ahead of the Curve in Science and Technology - OZY [Last Updated On: August 18th, 2024] [Originally Added On: December 29th, 2019]
- The Race To Find A Cure For Aging - Medium [Last Updated On: August 18th, 2024] [Originally Added On: January 1st, 2020]
- Hard work and dedication honored - Union Daily Times [Last Updated On: August 18th, 2024] [Originally Added On: January 23rd, 2020]
- Meet the people who think soaking in a frozen Minneapolis lake is the secret to good health - Minneapolis Star Tribune [Last Updated On: August 18th, 2024] [Originally Added On: January 24th, 2020]
- BOYS SWIMMING: Tigersharks top Waconia in conference dual - Crow River Media [Last Updated On: August 18th, 2024] [Originally Added On: January 25th, 2020]
- David Sinclair on NMN and Epigenetics | | LEAF [Last Updated On: August 18th, 2024] [Originally Added On: January 25th, 2020]
- Brave Cashel Community School get the better of St Augustine's to set-up a Munster hurling final clash with Doon - TipperaryLive.ie [Last Updated On: August 18th, 2024] [Originally Added On: January 28th, 2020]
- Diane Francis: Treating aging like a disease is the next big thing for science - Financial Post [Last Updated On: August 18th, 2024] [Originally Added On: January 28th, 2020]
- Letter: Yes to Green Growth | Opinion - Southern Pines Pilot [Last Updated On: August 18th, 2024] [Originally Added On: January 28th, 2020]
- Kelty Hearts 4-1 Caledonian Braves: Third straight defeat for Braves - Motherwell Times [Last Updated On: August 18th, 2024] [Originally Added On: February 6th, 2020]
- Is soaking in a frozen lake the secret to good health? - The Detroit News [Last Updated On: August 18th, 2024] [Originally Added On: February 12th, 2020]
- Letter:Deputy Is Vindicated | Opinion - Southern Pines Pilot [Last Updated On: August 18th, 2024] [Originally Added On: February 12th, 2020]
- BOYS SWIMMING: Chargers take fifth at WCC Championships; look ahead to sections - Crow River Media [Last Updated On: August 18th, 2024] [Originally Added On: February 12th, 2020]
- Lifespan: The New Science Behind Anti-Aging and Longevity that Can Help You Live to 100 - Thrive Global [Last Updated On: August 18th, 2024] [Originally Added On: February 19th, 2020]
- Not fasting is killing us, but fasting can hurt us too. Here's what to do. - Mashable [Last Updated On: August 18th, 2024] [Originally Added On: February 21st, 2020]
- Anti-Aging Researcher David Sinclair Takes Metformin, NMN ... [Last Updated On: August 18th, 2024] [Originally Added On: February 22nd, 2020]
- Movers and Shakers Week Ending 2.28.20 - milehighcre.com [Last Updated On: August 18th, 2024] [Originally Added On: February 28th, 2020]
- Health inequality in England was bad. It has got worse - The Economist [Last Updated On: August 18th, 2024] [Originally Added On: February 28th, 2020]
- Southland couple join volunteers to help future proof Southland A&P Show - Stuff.co.nz [Last Updated On: August 18th, 2024] [Originally Added On: March 3rd, 2020]
- Pilot Wins Top Honors at Awards Ceremony | Business - Southern Pines Pilot [Last Updated On: August 18th, 2024] [Originally Added On: March 3rd, 2020]
- Flipping the switch on the ageing process - The Age [Last Updated On: August 18th, 2024] [Originally Added On: March 21st, 2020]
- 7 books to read while in coronavirus quarantine or isolation - The CEO Magazine [Last Updated On: August 18th, 2024] [Originally Added On: March 28th, 2020]
- Remembering loved ones who have passed away - the 68 death notices in North Staffordshire this week - Stoke-on-Trent Live [Last Updated On: August 18th, 2024] [Originally Added On: March 31st, 2020]
- Can canine coronavirus drug indomethacin be used in treating humans suffering from COVID-19? - MEAWW [Last Updated On: August 18th, 2024] [Originally Added On: April 11th, 2020]
- Is There Any Legitimate Health Advice in Gwyneth Paltrow's "Goop Lab"? - InsideHook [Last Updated On: August 18th, 2024] [Originally Added On: April 11th, 2020]
- Will Universities, Colleges, And Law School Campuses Be Open In Fall 2020? - Above the Law [Last Updated On: August 18th, 2024] [Originally Added On: April 11th, 2020]
- 'Refreshingly honest' dealer who ran Perth drug den will be sent home to Poland - The Courier [Last Updated On: August 18th, 2024] [Originally Added On: April 14th, 2020]
- Has Harvard's David Sinclair Found the Fountain of Youth? [Last Updated On: August 18th, 2024] [Originally Added On: April 20th, 2020]
- Carole Carson: Adventures in Aging Seven myths about getting older - The Union of Grass Valley [Last Updated On: August 18th, 2024] [Originally Added On: April 25th, 2020]
- Hide and Hedonism invite guests to a virtual wine dinner - Spear's WMS [Last Updated On: August 18th, 2024] [Originally Added On: May 1st, 2020]
- Budget realities from COVID-19 cut $40.6 million from Prince William budgets - Inside NoVA [Last Updated On: August 18th, 2024] [Originally Added On: May 1st, 2020]
- Drug Use is Transmitted from Old to Young - UPJ Athletics [Last Updated On: August 18th, 2024] [Originally Added On: May 16th, 2020]
- Fife woman breached Asbo by having illicit party at home during lockdown - The Courier [Last Updated On: August 18th, 2024] [Originally Added On: May 19th, 2020]
- A Harvard Geneticist Wants To Sell A Magical ... - HuffPost [Last Updated On: August 18th, 2024] [Originally Added On: June 9th, 2020]
- Jennifer Aniston: How The Morning Show felt like 20 years of therapy - The Detroit News [Last Updated On: August 18th, 2024] [Originally Added On: August 26th, 2020]
- Woods, Waters, and Wildlife: Buy Licenses Now! | FCT News - Freestonecountytimesonline [Last Updated On: August 18th, 2024] [Originally Added On: August 29th, 2020]
- Editorial: Five Birdies That Signal Good Work | Opinion | thepilot.com - Southern Pines Pilot [Last Updated On: August 18th, 2024] [Originally Added On: September 3rd, 2020]
- We all suffer when COVID-19 locks the elderly out of societal participation - The Investment Observer [Last Updated On: August 18th, 2024] [Originally Added On: September 18th, 2020]
- DS4 to rock Morden live at The Sound Lounge - Your Local Guardian [Last Updated On: August 18th, 2024] [Originally Added On: September 26th, 2020]
- How newly unemployed over-50s can start-up again - The Guardian [Last Updated On: August 18th, 2024] [Originally Added On: October 8th, 2020]
- 100 years old will be the new 60 | Health & Wellness - CL Charlotte [Last Updated On: August 18th, 2024] [Originally Added On: October 16th, 2020]
- Brexit casts doubt over UK pension rights - Interactive Investor [Last Updated On: August 18th, 2024] [Originally Added On: October 16th, 2020]
- Cancer. How close are we to winning the war? - Switzer [Last Updated On: August 18th, 2024] [Originally Added On: October 16th, 2020]
- Where Sabrina the Teenage Witch cast are now - hit TV shows and unrecognisable star - Mirror Online [Last Updated On: August 18th, 2024] [Originally Added On: October 28th, 2020]
- Caledonian Braves can 'breathe a bit easier' after first win says boss Ricky Waddell - MSN UK [Last Updated On: August 18th, 2024] [Originally Added On: October 28th, 2020]
- Why Aren't We Talking More About Nutrition Amid COVID-19? - Anti Aging News [Last Updated On: August 18th, 2024] [Originally Added On: November 2nd, 2020]
- We should allow ourselves to be #pharmaproud - - pharmaphorum [Last Updated On: August 18th, 2024] [Originally Added On: November 19th, 2020]
- 6 Anti Aging Benefits of Metformin - The Shepherd of the Hills Gazette [Last Updated On: August 18th, 2024] [Originally Added On: November 19th, 2020]
- Hokitika father charged with murder initially claimed son fell out of bed - Stuff.co.nz [Last Updated On: August 18th, 2024] [Originally Added On: November 19th, 2020]
- Scientists Uncover Approach That Could Reverse Age-Related Vision Loss - Science Times [Last Updated On: August 18th, 2024] [Originally Added On: December 6th, 2020]
- HTLS 2020: A pill that can reverse ageing? Yes, it will be possible, says Dr Sinclair - Hindustan Times [Last Updated On: August 18th, 2024] [Originally Added On: December 6th, 2020]
- Reversing vision loss by turning back the aging clock - FierceBiotech [Last Updated On: August 18th, 2024] [Originally Added On: December 6th, 2020]
- Pill to reverse ageing in 30 years? Why not, says Harvard professor Dr David Sinclair - Hindustan Times [Last Updated On: August 18th, 2024] [Originally Added On: December 6th, 2020]
- Get younger reverse ageing and increase your health span - Have a Go News [Last Updated On: August 18th, 2024] [Originally Added On: December 8th, 2020]
- Over 50s Spending Spree Boosts Economy By Billions - Money International [Last Updated On: August 18th, 2024] [Originally Added On: January 20th, 2021]
- Hunger in Milwaukee and the World: What We Can Do About It - Wisconsin Public Radio News [Last Updated On: August 18th, 2024] [Originally Added On: February 15th, 2021]
- Woman's 'nasty' skin infection most likely caused by swimming in sea after shaving legs - Stuff.co.nz [Last Updated On: August 18th, 2024] [Originally Added On: August 3rd, 2021]
- David Sinclair | The Sinclair Lab [Last Updated On: August 18th, 2024] [Originally Added On: December 21st, 2021]
- David Sinclair Supplements List Deep Dive - Updated 2021 [Last Updated On: August 18th, 2024] [Originally Added On: December 21st, 2021]
- Don't Listen to Intermittent Fasting Influencers, The Science Doesn't Back It Up - InsideHook [Last Updated On: August 18th, 2024] [Originally Added On: April 27th, 2022]
- David Sinclair Post-2022 Canyons by UTMB 100k Interview - iRunFar [Last Updated On: August 18th, 2024] [Originally Added On: April 27th, 2022]
- Authorized Biography Of The Rolling Stones Charlie Watts Launched In London - uDiscover Music [Last Updated On: August 18th, 2024] [Originally Added On: September 24th, 2022]
- David Sinclair Supplements (2022 List) | Brands for Anti-Aging! [Last Updated On: August 18th, 2024] [Originally Added On: September 24th, 2022]