DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/3tdb7f/telomerases_chemi) has announced the addition of John Wiley and Sons Ltd's new book "Telomerases. Chemistry, Biology and Clinical Applications" to their offering.

This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere functions of telomerase and the role of telomerase in cellular senescence, aging and cancer. Its relationship to retrotransposons, a class of mobile genetic elements that shares similarities with telomerase and serves as telomeres in selected organisms, are also reviewed.

Key Topics Covered:

1 The Telomerase Complex: An Overview

Johanna Mancini and Chantal Autexier

2 Telomerase RNA: Structure, Function, and Molecular Mechanisms

Yehuda Tzfati and Julian J.-L. Chen

3 TERT Structure, Function, and Molecular Mechanisms

Emmanuel Skordalakes and Neal Lue

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Research and Markets: Telomerases. Chemistry, Biology and Clinical Applications 2012 Book Features Topics such as Off ...