Found in red wine, red or purple grapes, some berries,and dark chocolate, resveratrol is a naturally-occurring polyphenol compound that has been touted as a potential remedy for a range of age-related conditions, including heart disease, diabetes, cancer, and Alzheimer's disease.

Said to contribute to the "French paradox"the observation that people living in France tend to eat a lot of cheese, butter, and other fatty foodsyet have a low incidence of heart diseaseresveratrol consumption has been found to mimic a calorie-restricted diet (which studies have shown can play a role in longevity) and decrease chronic inflammation in the body.

Much of the research pointing to the benefits have been laboratory or animal-based studies. So far, research on resveratrol's effectiveness in humans has yielded mixed results. Here's a look at some key study findings:

1) HeartHealth

For a review published in Clinical Nutrition in 2015, researchers analyzed six previously published studies on the effects of resveratrol on blood pressure, and concluded that resveratrol didn'tsignificantly reduce blood pressure. Higher doses of resveratrol (over 150 mg per day), however, werefound to significantly decrease systolic blood pressure (the top number on a blood pressure reading).

Another review, published in the International Journal of Cardiology in 2015, examined the effectiveness of resveratrol on cardiovascular risk factors. After analyzing 10 previously published studies, researchers concluded that the analysis did not suggest any benefit of resveratrol supplementation on heart disease risk factors, including levels oftotal cholesterol, LDL cholesterol, triglycerides, blood pressure, and C-reactive protein (a blood protein that is raised when there is inflammation, including in heart disease).

2) Aging

There's some evidence that resveratrol may not prolong life, according to research on people living in Tuscany who consume a diet rich in resveratrol from food sources like red wine. In astudy published in JAMA Internal Medicine in 2014, 783 men and women 65 years or older were followed from 1998 to 2009.

During that time, intake of red wine (as measured by urine levels of resveratrol metabolites), didn't change the likelihood of dying from any cause, the incidence of heart disease or cancer, or markers of inflammation.

3) Cancer

A number of preliminary studies suggest that resveratrol may have anti-cancer effects. In a2016 animalstudy, for instance, resveratrol suppressed ovarian tumor regrowth after chemotherapy. Published in Cancer, the study found that resveratrol inhibited the uptake of glucose by cancer cells (many cancer cells depend on glucose as their energy supply).

Despite these findings, the data from the limited human clinical trials have shown inconsistent outcomes and the American Cancer Society cautions that randomized clinical trials are needed to confirm the cancer-fighting effects of resveratrol. (There is also some concern that resveratrol may influence levels of estrogen and other hormones.)

Trans-resveratrol is a form of resveratrol commonly found in supplements. Proponents often claim that trans-resveratrol is the most stable form of resveratrol.

In addition to food sources, resveratrol is also found in Japanese knotweed (Polypodium cuspidatum), grape seed extract, cissus quadrangularis, and white mulberry (Morus alba).

Pterostilbeneis a compound related to resveratrol.

LIttle is known about the safety of long-term or high dose use of resveratrol.

Since resveratrol may possess estrogen-like properties, some medical experts recommend that people with hormone-sensitive cancers (including cancers of the breast, ovary, or uterus), pregnant women, and children avoid taking resveratrol.

In addition, resveratrol could interact with blood thinners like warfarin, aspirin, and ibuprofen, which may raise your risk of bleeding.

According to one study, high-dose resveratrol supplementation was associated with fever,reduced blood cells, and decreased blood pressure.

There is some concern that high doses ofresveratrol supplements could lead to kidney problems in some people.

Supplements haven't been tested for safety and due to the fact that dietary supplements are largely unregulated, the content of some products may differ from what is specified on the product label. You can get tips on usingsupplementshere.

Since the compound was first described in 1992, resveratrol has been studied for its much-touted benefits on the brain, heart, and lifespan, but recent research casts doubt on the notion that resveratrol supplementscan help you live longer or lower your risk of heart disease or cancer.

If you're wondering whether a daily glass of red wine or piece of dark chocolate will improve your health, some researchers note that consumption of red wine, dark chocolate, and some berries has been found to decrease inflammation and have heart-healthy benefits, and suggest that other compounds in these foods may contribute to these benefits.

It's impossible, however, to get anywhere near the doses used in studies from food sources. Many of the studies have used a dose of about 100 mg or more of resveratrol, while a 5-ounce glass of red wine only has about 1 mg of resveratrol.

It's important to note that increasing your intake of red wine comes with a trade-off.Consuming too much may raise your risk of high bloodpressure, liver damage, obesity, and some forms of cancer.

To boost your intake without consuming alcohol, try eating foods like grapes, raspberries, plums,blueberries, cranberries, grape tomatoes, and pomegranate (all of which are rich in resveratrol and a range of antioxidants and nutrients).

If you're still considering using resveratrol supplements, talk to your healthcare provider before starting your supplement regimen to weigh the pros and cons and discuss whether it's appropriate for you.

Sources:

Liu Y, Ma W, Zhang P, He S, Huang D.Effect of resveratrol on blood pressure: a meta-analysis of randomized controlled trials.Clin Nutr. 2015 Feb;34(1):27-34.

Sahebkar A, Serban C, Ursoniu S, et al.Lack of efficacy of resveratrol on C-reactive protein and selected cardiovascular risk factors--Results from a systematic review and meta-analysis of randomized controlled trials.Int J Cardiol. 2015;189:47-55.

Semba RD, Ferrucci L, Bartali B, et al.Resveratrol levels and all-cause mortality in older community-dwelling adults.JAMA Intern Med. 2014 Jul;174(7):1077-84.

Tan L, Wang W, He G, et al.Resveratrol inhibits ovarian tumor growth in an in vivo mouse model.Cancer. 2016 Mar 1;122(5):722-9.

Disclaimer: The information contained on this site is intended for educational purposes only and is not a substitute for advice, diagnosis or treatment by a licensed physician. It is not meant to cover all possible precautions, drug interactions, circumstances or adverse effects. You should seek prompt medical care for any health issues and consult your doctor before using alternative medicine or making a change to your regimen.

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Resveratrol: Benefits and Uses - verywellfit.com

Latest trends report on globalResveratrolmarket 2020 with upcoming industry trends, size, share, top companies profiles, growth report and forecast by 2025.

The authors of the study have derived authentic data relating to the market, to identify the areas that promise the highest growth rate in the coming years. The report suggests that government funding and support, increasing rate of consumption of theGlobal Resveratrol Market, and the shift in consumer preferences will facilitate the growth of the industry with a sizeable CAGR of XX% in the forecast duration from 2019 to 2025.

Request Free Sample Report of Resveratrol Market Report @https://www.ricercaalfa.com/page/request-sample/58167/Resveratrol-Market.html

In market segmentation by manufacturers, the report covers the following companies-DSMEvolvaSabinsaInterHealthMayproLaurus LabsJF-NATURALGreat Forest BiomedicalShaanxi Ciyuan BiotechChengdu YazhongChangsha Huir Biological-techXian Gaoyuan Bio-ChemXian Sinuote

A conscious effort is made by the subject matter experts to analyze how some business owners succeed in maintaining a competitive edge while the others fail to do so makes the research interesting. A quick review of the realistic competitors makes the overall study a lot more interesting. Opportunities that are helping product owners size up their business further add value to the overall study.

In market segmentation by types of Resveratrol, the report covers-SyntheticPlant ExtractFermentation

The evaluation also includes the rates of production and consumption, gross revenue, and average product price and market shares of key players. The information gathered is further broken down by including regional markets, production plants, and product types available in the market. Other key points, like competitive analysis and trends, concentration rate, mergers & acquisitions, expansion tactics, which are vital to establishing a business in the sector, have also been included in the report.

For more information on this report, Visit @https://www.ricercaalfa.com/page/enquire/58167/Resveratrol-Market.html

In market segmentation by applications of the Resveratrol, the report covers the following uses-Dietary SupplementCosmeticFood and BeverageOthers

The report has been drafted after an extensive assessment of information gathered through both primary (through interviews, surveys, and observations of seasoned analysts) and secondary (which entails reputable paid sources, trade journals, and industry body databases) sources of data collection. It also includes an exhaustive qualitative and quantitative evaluation by focusing on the information collected from industry analysts and market players across the value chain.

The report also takes into consideration the growth trends seen in the parent market, micro- and macro-economic indicators, and regulations and governmental policies, among other factors. By doing so, the report predicts the growth prospects in the market segments for the forecast period.

Resveratrol Market segments and sub-segments:

Resveratrol Market: Regional analysis includes:Asia-Pacific(Vietnam, China, Malaysia, Japan, Philippines, Korea, Thailand, India, Indonesia, and Australia)Europe(Turkey, Germany, Russia UK, Italy, France, etc.)North America(United States, Mexico, and Canada.)South America (Brazil etc.)The Middle East and Africa(GCC Countries and Egypt.)

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The Resveratrol market research addresses the following queries:

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New products containing the latest "it" ingredient are released daily into the skin care market. Recently, the popularity of resveratrol (an antioxidant found in the skin of red grapes) has skyrocketed, both in the skin and health care worlds. In a nutshell, this wonder remedy has been found to help restore cellular health on all levels, from repairing damage caused by environmental toxins to regulating metabolism as the body ages.

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One of the biggest concerns in skin care is combating the effects of aging. As you age, collagen levels in the skin are broken down by free radicals from environmental factors such as UV rays and toxins. Skin, therefore, becomes more susceptible to cellular damage and signs of aging, like fine lines and wrinkles. Resveratrol, also touted as a potent anti-stress remedy, has the ability to reverse skin damage and restore it to a more healthy, youthful state.

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Skin is not the only organ of the body that ages. Though you can't see your body aging internally, most would agree you can certainly feel it. Resveratrol has been credited with actually stimulating anti-aging genes in the body to slow down the gradual decline of internal systems. It has also been found to support heart health, cognitive function and a healthy metabolism. The best part? You can get your antioxidant fix from a glass of your favorite red wine.

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There is no shortage of lotions, creams and serums containing resveratrol available, so you won't have a problem finding one. The antioxidant's anti-aging, anti-inflammatory and hydrating properties have made it a mogul in skin care. While you may think that buying the product containing the most resveratrol is the best, keep in mind that skin care is subjective and that it's actually the combination of other ingredients that can make or break a product. Shop for face creams manufactured by well-known brands and read reviews online before choosing a product. You may need to try a few before you find one that is right for you.

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While resveratrol has many wonderful attributes, it can also become toxic in high doses. This risk is more inherent when ingesting resveratrol supplements than when slathering on face cream, but in both cases it is best to do your homework and pay attention to dosage amounts on labels before orally taking resveratrol or using a skin care product containing the antioxidant.

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Which Face Cream Contains the Most Resveratrol? | Our ...

Presented in partnership with MANCAN

Its an uncertain time for the entire world right now, with all of us (hopefully) practicing social distancing by isolating ourselves to stop this pandemic from spreading. That means lots of free time sitting around and binge-watching TV shows and movies while still trying to FaceTime with friends and family.

While thats a great way to keep yourself busy and entertained, theres just one problem: What do you toast during a makeshift Happy Hour? Since were classy AF, our choice is MANCAN wine, which is the better way to smash some delicious vino in the comfort of your own home right now.

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A great alternative to all those big, heavy, glass bottles of wine most of us are accustomed to, MANCAN wine is a lighter way to toast to good friends and family during quarantine, and, since it comes in a can, is easier to ship and store during these uncertain times.

One other benefit? According to a study from the University of Texas, red wine can boost your immune system, meaning that, you guessed it, enjoying some of MANCANs red wine could bring health benefits during a time when nobody wants to get sick. Heres what the study revealed.

For the first time, researchers have demonstrated that resveratrol which is abundantly available in red wine and also found in grapes, peanuts and berries can ease some of the negative effects on the immune system caused by a diet high in fat.

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So, even if youre not the biggest red wine fan, MANCAN offers up varieties that should satisfy your tastebuds.

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Already a four-time recipient of Wine Enthusiast Magazines coveted Best Buy award, MANCAN is the ideal way to stock up while youre stuck indoors right now. All selections are hand-crafted in Sonoma County in California, and are available atmajor retailers like Whole Foods, Walmart, Meijer and others, but, since were all trying to be safe right now, its best to go ahead and snag yours over at MANCANs online shop, where youll find a bunch of mixed pack and 8-packs of the different varieties.

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The BroBible team writes about gear that we think you want. Occasionally, we write about items that are a part of one of our affiliate partnerships and we will get a percentage of the revenue from sales.

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Purest Vantage Resveratrol formula is highly potent, and this is why it continues to gain an increasing interest and trust among many consumers.

(Newswire.net -- January 31, 2020) Orlando, FL -- There are many types of antioxidants that can be found in plant sources. However, it is resveratrol that appears to be gaining an increasing interest among many researchers and clinicians.

Resveratrol is found to be one of the most unique antioxidants. Today, there are many people who do not have adequate levels of antioxidants in their bodies. Most of these people suffer from certain symptoms and diseases.

Antioxidants have long been found to be highly therapeutic. It is believed to be useful in fighting free radical damage, which is essential for human health and longevity.

According to some experts, resveratrol has the potential to cross the blood-brain barrier. This helps offer protection to the brain as well as the nervous system.

Some studies even reveled that resveratrol could protect cells from free radical damage as well as inhibit the spread of cancer. This is especially true to individuals who suffer from prostate cancer. This antioxidant could also reduce blood pressure levels and keep the heart healthy.

Some researchers even suggest that resveratrol has the ability to enhance the elasticity of the blood vessels. Further, this powerful antioxidant could also help normalize anti-inflammatory response and aid in the prevention of Alzheimers disease.

Resveratrol has been found to be highly effective in warding off a variety of diseases linked with aging. It is even called the fountain of youth due to its high potential in increasing lifespan.

In animal studies, it was found that this powerful healing antioxidant aided in the improved running performance of mice. It also successfully increased the lifespan of human cells. Further, this therapeutic agent could also offer the same health benefits as exercise.

Individuals who want to utilize the therapeutic effects of resveratrol may take into account consuming more grapes and other plant sources such as peanuts and dark chocolate. There are also formulas available like Purest Vantage Resveratrol supplement.

It would be quite easy to obtain the healing effects of resveratrol through supplementation. Supplements are handy and are easy to swallow. What makes them even more beneficial is that they normally contain abundant levels of resveratrols therapeutic goodness.

Purest Vantage Resveratrol formula is highly potent, and this is why it continues to gain an increasing interest and trust among many consumers. What makes it even more beneficial is that it also contains other therapeutic ingredients, and is free from GMOs, binders, and fillers.

It is a proudly U.S.-made formula that is manufactured without the involvement of dangerous processes. It even comes with a complete customer satisfaction guarantee offer (http://www.amazon.com/Resveratrol-Supplement-Trans-Resveratrol-Additional-Polyphenol/dp/B01N3LZY3O).

Purest Vantage is passionate and dedicated to developing high-quality products that assist people in maintaining optimal health, enabling them to enjoy all the benefits a healthy lifestyle offers.

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Resveratrol Found To Be One Of The Most Unique Antioxidants - Newswire

Fromnausea andheadaches toanxiety and dehydration, we all know what can happen when you consume too much alcohol. But how does over-imbibing affect your skin? Consideringalcohol's profound mental and physical effects, weseriously doubtthat your skinyour body's largest organcan escape a night of partying unscathed.

To answer thisquestion, we tapped Morgan Rabach, a board-certified dermatologist and the co-founder ofLM Medical. Below, read up on the effects of alcohol on skin, thebest and worst drinks for skincare, and how to help your skin recover from a night out.

"Alcohol is a diuretic, which means it causes water to leave your body, thus dehydrating your skin," Rabach says. "When your skin is dehydrated, it loses plumpness, and fine lines and wrinkles become more apparent."Alcohol also reduces antioxidants in the skin, particularly vitamin A, which helps with cell renewal and turnover. A lack of this essential compound inhibits your body's natural ability to ward off free-radical damage and protect your skin from environmental stressors.

What's more, "alcohol is pro-inflammatory, meaning it can cause flares in certain inflammatory skin conditions like acne, rosacea, and psoriasis," she adds. This is partly due to the fact that alcohol causes vasodilation, which isthe widening of blood vessels. This increases redness and flushing and can even give rise to facial spider veins and a puffy complexion.

It goes without saying that the more you drink, the worse your skincare hangover symptoms will be. But as Nancy Samolitis, MD, points out,not all alcohols are created equal.

Generally speaking, she suggests avoiding any sugar-heavy wines, cocktails, or mixers, as they can increase inflammation, spike your blood sugar, and lead to acne breakouts. Stick to pure additives likeclub soda and lemon or lime juice to add flavor without excess sugar.

When it comes to selecting your drink of choice, antioxidant-rich red wine is first on her list. The polyphenols and resveratrol can actually benefit your body and your skin. As far as liquor goes, clear spirits like tequila and vodka containminimal sugars and few added ingredients.

There are plenty of steps you can take before and after drinking to help your skin recover. "Drinking one glass of water per drink helps prevent dehydration,and drinking water overnight also helps,"explains Rabach. "Remember to wash your face when you get home, and always remove makeup! This also prevents pores from getting clogged."

As far as skincare products go, Rabachswears byantioxidant-rich serums and lush hydrators like hyaluronic acid after a long night out. These healing ingredients will replenish your skin and draw much-needed moisture and hydration backto your epidermis.

You can also tailor your skincare routine to yourunique needs. If you notice a new pimple or puffy under-eyes after a night out, by all means, reach for your favoritespot treatmentor eye cream.

Dr. Barbara Sturm Hyaluronic Acid Serum ($300)

This powerful hyaluronic acid serum will give your skin the potent dose of hydration it needs.

Avne Soothing Sheet Mask x 5 ($42)

These soothing sheet masks were made specifically for dry, dehydrated, and puffy skin.

Caudalie Premier Cru Anti-Aging Serum ($150)

Formulated with polyphenols, resveratrol, and hyaluronic acid, this antioxidant serum will quench your skin'sthirst.

SkinCeuticals A.G.E. Eye Complex ($98)

This top-ratedeye complexis the answer to your dark under-eye circles.

Neutrogena Hydro Boost Water Gel Face Moisturizer ($16)

This budget, dermatologist-recommended moisturizer is formulated with replenishing hyaluronic acid.

Dr. Jart Soothing Hydra Solution Sheet Mask ($6)

This ultra-hydrating mask is formulated with moisturizing Aquaxyl, xylitol, and aloe vera.

Joanna Vargas Rescue Serum ($150)

The name of this antioxidant-rich serum says it all.

Drunk Elephant B-Hydra Intensive Hydration Serum ($48)

Formulated withpro-vitamin B5 and pineapple ceramide, B-Hydra is a cool drink of water for thirsty skin.

IS Clinical Hydra-Intensive Cooling Masque ($85)

With hyaluronic acid and aloe vera, thisanti-inflammatorygel mask will soothe, calm, and hydrate your skin.

Tata Harper Repairative Anti-Aging Moisturizer ($116)

This anti-aging moisturizer is formulated with powerful dual-weight hyaluronic acid and firming buckbean extract.

Next up: This Is What Happens to Your Body When You Quit Alcohol

This article originally appeared on The Thirty

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This Is What Happens to Your Skin When You Drink Alcohol - Yahoo Lifestyle

Its beyond disappointing to discover that some of the health foods we buy are actually bad for us. No one likes to spin their wheels; and yet, many of us are spending our hard-earned time and money making healthy food choices that arent getting us anywhere.

This is a mistake none of us wants to make, which is why its important to get familiar with the common junk foods masquerading as health foods.

Related Reading: The Healthiest Diet for 2020 Has Been Decided

Here are five important ones to know:

Chowhound

Granola has long been marketed as a health food. And at first glance, it seems legit. (Its made with oats, dried fruit, and nuts, right?)

Unfortunately, research has also shown that oats commonly contain unhealthy levels of glyphosate, the main ingredient in Roundup, which has been added to Californias list of chemicals known to the state to cause cancer. And with the combination of dried fruit and added sources of sugar like honey, maple syrup, and coconut sugar, granola can be a sugar bomb.

But its not all bad news. If you stick to organic products that have no added sugaror make your own easy granola at home!you can still enjoy your morning yogurt and granola parfait.

Chowhound

When you think of healthy meal choices, a salad is probably the first image that comes to mind. And most salads are, indeed, healthy. That said, you really want to watch out for the dressing youre using, which can seriously sabotage the health of your meal. Salad dressings are a huge hidden source of sugar and less-than-healthy oils like soybean oil, corn oil, and canola oil.

Want to keep it simple and make sure youre not topping your healthy meal with something unhealthy? Next time youre at the salad bar, ask for olive oil, a lemon squeeze, and salt and pepper. If youre eating at home, opt for homemade dressingstry one of these fresh and easy salad dressing recipesinstead of store-bought ones. They taste better and youll know exactly whats going in them.

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Pellegrino lovers, dont panic. Not all sparking water falls under the unhealthy category. What you want to watch out for on the ingredients list of these products is the term natural flavors, which is found in many fan-favorite flavored sparkling water drinks.

So what are natural flavors, exactly? No one is really sure. The FDA does define the term, but there are loopholes in the definition that really blur the line between natural and artificial flavors. According to the Environmental Working Group, a review paper found that artificial and natural flavorings can be unspecified mixtures of as many as 100 flavoring substances and solvents, emulsifiers, and preservatives.

So basically, the term natural flavor doesnt mean much at all; and it definitely doesnt mean the product is healthy or free from artificial flavors.

Related Reading: 8 Stylish Water Bottles Thatll Make You Want to Hyrdate

To make sure you know exactly whats in the beverage youre drinking, buy from brands that are transparent about the flavoring agents they use. For example, Spindrift sparkling waters are made with a touch of real squeezed fruit.

Chowhound

But its high in protein! a chorus of Greek yogurt lovers cries out. Admittedly, Greek yogurt is high in proteinwith about 19 grams of protein per servingand also contains good bacteria that can be beneficial for the gastrointestinal tract.

But if youre eating cows milk yogurt regularly, hormones are a concern. Studies have shown that the presence of hormones in dairy products has the potential to disrupt the endocrine system and unfortunately, yogurt is one of the most common sources of dairy in the United States. If youre buying yogurt, look for products made from cows that were not treated with hormones or buy yogurt made from plant-based ingredients like almonds, oats, and cashews.

According to the Harvard T.H. Chan School of Public Health, a five-ounce container of yogurt can also contain up to 25 grams of sugarand most of that sugar is coming from added sweeteners. When youre in the yogurt aisle, follow their advice and if you see sugar or other forms of sugar among the top four ingredients in the Ingredients list, consider choosing a lower sugar yogurt or use plain yogurt with your own addition of fresh fruit or a drizzle of honey.

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A quick internet search will reveal thousands of articles claiming that red wine is healthy. And while it does contain antioxidants like resveratrol, its far from a health food that you should consume with abandon. According to the Mayo Clinic, studies on resveratrol are mixed. Some research shows that resveratrol could be linked to a lower risk of inflammation and blood clotting, which can lower your risk of heart disease. But other studies found no benefits from resveratrol in preventing heart disease, they wrote. Plus, red wine contains a lot of sugar and of course, it contains alcohol, which can have extremely toxic effects.

Yes, studies have suggested that one or two drinks a day can benefit your health, but just as many have shown that no amount of alcohol is good for your health and that even one drink a day can increase your risk of certain diseases, such as breast cancer.

Finding foods that are actuallyhealthy can feel like looking for a needle in a haystack. But they do exist! The key is to become a discerning ingredients list reader and find brands that are going above and beyond to stick to real, simple ingredients.

Header image by Chowhound

Excerpt from:
5 Health Foods That Arent Actually Good for You - Chowhound

Food gives us the nutrients we need to survive, and we know a balanced diet contributes to good health. Beyond this, many people seek out different foods specifically for their health benefits, hoping eating certain things might prevent or treat particular conditions. Here are five options that aren't nearly as beneficial as their reputation suggests.

Its true many foods contain bioactive compounds chemicals that act in the body in ways that might promote good health. These are being studied in the prevention of cancer, heart disease and other conditions.

But the idea of food as medicine, although attractive, is easily oversold in the headlines. Stories tend to be based on studies done in the lab, testing concentrated extracts from foods. The effect seen in real people eating the actual food is going to be different to the effects in a petri dish.

If you do the maths, youll find you actually need to eat enormous amounts of particular foods to get an active dose of the desired element. In some cases, this might endanger your health, rather than protecting it.

These four foods (and one drink) show the common healing claims around the foods we eat dont always stack up.

Cinnamon, which contains a compound called cinnamaldehyde, is claimed to aid weight loss and regulate appetite.

There is evidence cinnamaldehyde can reduce cholesterol in people with diabetes. But this is based on studies of the chemical in large doses not eating the spice itself.

These studies give people between 1 and 6 grams of cinnamaldehyde per day. Cinnamon is about 8% cinnamaldehyde by weight so youd have to eat at least 13 grams of cinnamon, or about half a supermarket jar, per day. Much more than youd add to your morning porridge.

The headlines on the health benefits of red wine are usually because of a chemical in grape skins called resveratrol. Resveratrol is a polyphenol, a family of chemicals with antioxidant properties.

Its been claimed resveratrol protects our cells from damage and reduces the risk of a range of conditions such as cancer, type 2 diabetes, Alzheimers disease, and heart disease.

There is some limited evidence that resveratrol has benefits in animal models, although studies done in humans have not shown a similar effect.

It varies by wine, but red wine contains about 3 micrograms (about 3 millionths of a gram) of resveratrol per bottle. The studies that have shown a benefit from resveratrol use at least 0.1 grams per day (thats 100,000 micrograms).

To get that much resveratrol, youd have to drink roughly 200 bottles of wine a day. We can probably all agree thats not very healthy.

Blueberries, like red wine, are a source of resveratrol, but at a few micrograms per berry youd have to eat more than 10,000 berries a day to get the active dose.

Blueberries also contain compounds called anthocyanins, which may improve some markers of heart disease. But to get an active dose there youre looking at 150-300 blueberries per day. More reasonable, but still quite a lot of fruit and expensive.

The news that dark chocolate lowers blood pressure is always well-received. Theobromine, a chemical in chocolate has been shown to lower blood pressure in doses of about 1 gram of the active compound, but not at lower doses. Depending on the chocolate, you could be eating 100g of dark chocolate before you reached this dose.

Chocolate is a discretionary food, or junk food. The recommended serve for discretionary foods is no more than 600 kilojoules per day, or 25g of chocolate. Eating 100g of chocolate would be equivalent to more than 2,000kJ.

Excess kilojoule consumption leads to weight gain, and being overweight increases risk of heart disease and stroke. So these risks would likely negate the benefits of eating chocolate to lower your blood pressure.

Turmeric is a favourite. Its good in curries, and recently weve seen hype around the tumeric latte. Stories pop up regularly about its healing power, normally based on curcumin.

Curcumin refers to a group of compounds, called curcuminoids, that might have some health benefits, like reducing inflammation. Inflammation helps us to fight infections and respond to injuries, but too much inflammation is a problem in diseases like arthritis, and might be linked to other conditions like heart disease or stroke.

Human trials on curcumin have been inconclusive, but most use curcumin supplementation in very large doses of 1 to 12 grams per day. Turmeric is about 3% curcumin, so for each gram of tumeric you eat you only get 0.03g of curcumin. This means youd have to eat more than 30g of tumeric to get the minimum active dose of tumeric.

Importantly, curcumin in turmeric is not very bioavailable. This means we only absorb about 25% of what we eat, so you might actually have to eat well over 100g of turmeric, every day, to get a reasonable dose of curcumin. Thats a lot of curry.

We all want food to heal us, but focusing on single foods and eating mounds of them is not the answer. Instead, a balanced and diverse diet can provide foods each with a range of different nutrients and bioactive compounds. Dont get distracted by quick fixes; focus instead on enjoying a variety of foods.

Emma Beckett, Postdoctoral Fellow (Human Molecular Nutrition), School of Medicine and Public Health, University of Newcastle and Gideon Meyerowitz-Katz, PhD Student/Epidemiologist

This article is republished from The Conversation under a Creative Commons license.

This story has been updated since its original publication.

Link:
These 5 Foods Aren't As Healthy As You Think - Lifehacker Australia

Dont be afraid to re-brand if needed. Most start-ups begin with a product, not a brand. As one adds more products, customers can get confused. The brand needs to hold it all together. If it doesnt, re-brand to get itright.

As a part of our series about entrepreneurs who transformed something they did for fun I had the pleasure of interviewing Dr. Glen Miller, Professor of Organic Chemistry & Chair of the Chemistry Department at the University of New Hampshire. He is also Founder, CTO and Chair of Vera Roasting Company, makers of the first and only coffee infused with resveratrol, the beneficial antioxidant found naturally in red wine. In his academic life, he is an authority in the area of organic chemistry and nanotechnology.

Thank you so much for doing this with us! Can you tell us a bit about your childhood backstory?

I was born in a very small town in central New York state called Chittenango, perhaps best known as the birthplace of Lyman Frank Baum, author of the American fairytale The Wizard of Oz. At the age of 9, I somehow contracted rheumatic fever which forced me out of school for the better part of a year, and this experience changed my lifes path. Until then, I was primarily concerned with football and basketball and other pursuits of an energetic and competitive young boy.

Forced to stay home (primarily in bed) for several months left me with nothing to do except read my school books and try to avoid falling behind. During this time, I became an independent learner in math, science, history and English.

When I returned to school, I realized that I was not behind, but well ahead of my peers in these subjects. That experience changed my perspective on learning and allowed me to channel my competitive nature into being the very student I could be.

What was the catalyst from transforming your hobby or something you love into a business? Can you share the story of your ah ha moment with us?

Im an organic chemist and have been for many years. Over this time, Ive studied many interesting organic compounds, including all-natural compounds that exhibit interesting physical and chemical properties. For years, I was keenly aware of resveratrol, the beneficial antioxidant found in red wine that gives red wine its heart healthy reputation. As an organic chemist, I understood at the molecular level how resveratrol was capable of quenching nasty free radicals that can be associated with the early onset of disease. It is indeed a remarkable antioxidant. I also understood that our bodies do not produce resveratrol. So, the only way we can benefit from resveratrol is to make it a regular part of our diet. And by regular, I mean every day. Few foods contain resveratrol at a significant concentration, red wine being the exception. Like most Americans, I do not drink red wine on a daily basis, so I was not deriving the benefits of resveratrol. Resveratrol supplements in pill form are largely ineffective due to a lack of solubility.

These facts were lingering in the back of my mind when, quite literally, while showering one morning it hit me! Coffee could be the perfect vehicle for resveratrol. A little research bolstered the idea: 82% of all US adults drink coffee and the average coffee drinker consumes 3.1 cups per day. Some kitchen research revealed to me that I could, in fact, take a page out of red wines playbook to infuse resveratrol into coffee beans and make resveratrol soluble (and therefore bioavailable) in coffee. That part is proprietary knowledge, but it ultimately led to Vera Roasting Company, a US Patent, and our signature coffee infused with resveratrol.

There are no shortage of good ideas out there, but people seem to struggle in taking a good idea and translating it into an actual business. How did you overcome this challenge?

This is so true. Good ideas are a dime a dozen; its the execution that counts. Since Vera Roasting Company was launched in December 2015, weve had some great luck and done some things by design really well, but weve also made some mistakes, been distracted by the wrong things at times, and missed out on some opportunities. Its been a constant learning curve for me, especially as I had zero training in running a business prior to Veras launch. The key is to keep learning and continuously improve execution.

Since day one, I have brought the expertise of business professionals into the company. This has included folks with experience in areas like creating a business plan, marketing, accounting, etc. Even so, the road to success has still been paved with potholes (and an occasional land mine). Ive had to make some tough decisions along the way, but we find ourselves in a great spot now. Nearly a year ago, I was fortunate to bring on an investor who has great vision, great energy and a wealth of valuable experience and contacts.

We also have a CEO, Tom Polcaro, who understands the unique value that we offer and who is working around the clock to grow the business. With their leadership, Vera Roasting Company has successfully rebranded with new packaging, a new website, new product offerings, new partners and collaborations, and a great buzz. Weve always had the healthiest and best tasting coffee on the market. Now we have a great plan forward to share this beneficial product with as many people as possible.

What advice would you give someone who has a hobby or pastime that they absolutely love but is reluctant to do it for a living?

I think the advice Id give would be a function of their age, experience and situation. I started this business at the age of 50 while in the midst of a successful career in academia. The advice Id give to someone in a similar situation would be a bit different than the advice Id give to a 20-something, straight-out-of-college entrepreneur. But in the end, my message to both would be this: youve got to be passionate about your ideas and your business in order to be successful. Surround yourself with knowledgeable, dedicated, positive people that share your vision and passion, and then go for it.

Its said that the quickest way to take the fun out of doing something is to do it for a living. How do you keep from changing something you love into something you dread? How do you keep it fresh and enjoyable?

Ive had a lot of fun on this journey. There have certainly been some challenging times but my overall experience has been quite favorable and full of rewards. I think the thing that keeps it fresh and interesting for me is that I love to take on new challenges and learn new things. Vera Roasting Company enables me to create and innovate on a regular basis, and to continue learning. Since our launch, Ive learned so many things, like how to create a business plan, how to raise capital, how to market using social media, the nuances associated with branding, etc. Vera Roasting has also allowed me to meet and partner with many smart, passionate people that I would not have met otherwise.

What is it that you enjoy most about running your own business? What are the downsides of running your own business? Can you share what you did to overcome these drawbacks?

I am the Founder, Chair and CTO of Vera Roasting Company, but I am not the CEO. Still, I stay heavily involved in all the companys business and have done so since our launch. One of the things I enjoy most about my role is the opportunity to further innovate and create new products.

Some time after our signature coffee with resveratrol was launched, I developed a Sunshine Blend coffee that is infused with both resveratrol and vitamin D3. Like all our coffees, our Sunshine Blend is super smooth and delicious, but it also delivers 400 IU of vitamin D3 per cup in order to help fight epidemic vitamin D3 deficiencies. A full 40% of all US adults have a vitamin D3 deficiency. I expected that our Sunshine Blend coffee would be popular with customers in Northern states, especially in the winter months when exposure to sunshine is reduced. However, to my great surprise, our Sunshine Blend is popular with customers all over the US, including southern states, and in every season including the summer.

It turns out that sunscreen and make-up on our faces and arms all but shut down natural vitamin D production for millions of Americans, so customers located in all corners of the US and during all seasons enjoy the benefits of our Sunshine Blend. This is the sort of outcome that really fires me up and keeps me motivated to continue to innovate.

Can you share what was the most striking difference between your actual job and how you thought the job would be?

Because I founded Vera Roasting Company while such a business novice, I really had no preconceived notions of what my job at Vera would entail. You could say that I was nave.

Has there ever been a moment when you thought to yourself I cant take it anymore, Im going to get a real job? If so how did you overcome it?

Start-ups can be difficult and there were certainly moments when I wondered if Id done the right thing by investing so much time, energy and effort into Vera Roasting Company. But throughout my life, Ive always been just stubborn enough to refuse the urge to quit. Im passionate about changing peoples lives, one cup of coffee at a time, and I just couldnt quit on my opportunity to do exactly that. During those trying times, I did what Ive always done in similarly trying times. I put my head down, jumped into the ditch and started digging. One shovel at a time.

Before I knew it, some serious headway had been made and things started looking a lot brighter. Im so glad I was stubborn. Vera Roasting Company has come a long way. We are growing into the worlds premier functional coffee company. Ive never been more optimistic about our company and its potential to improve lives, one cup at a time. I can hardly wait to see where we are a year from now, two years from now, five years from now. But for now, its head down and back to work!

Can you share a story about the funniest mistake you made when you were first starting? Can you tell us what lesson you learned from that?

Well, its not really a mistake but I have a funny story from the time when the company was just getting started. A few days before our official launch in December 2015, a local reporter prepared a story about Vera Roasting Company that ran in a local newspaper, the Portsmouth Herald. The story generated a little bit of local buzz about Vera Roasting and our unique coffee that delivered the same health benefits as red wine. Some orders trickled in over that weekend, as locals read the article.

The following Monday morning, I was wrapping up my semester of teaching organic chemistry at the University of New Hampshire. It was a few days before the final exam, and I was offering an optional review class which was attended by approximately 200 students. Unbeknownst to me, the local newspaper story was picked up by the AP and published in about 300 newspapers around the country, all while I was teaching my organic chemistry review class. I had set up my Vera Roasting email account on my cell phone such that whenever an order was received, I felt a buzz.

As I was reviewing organic chemistry with 200 students, my cell phone began to buzz. Within a matter of minutes, the frequency of buzzes increased dramatically. Students in the review class could not help but notice that my pants were buzzing loudly. Very soon, there were no longer individual buzzes, but instead a steady stream of endless buzzing noises. I set it on a table in front of me. The table was facing my students and they laughed as it danced across the table from the endless stream of buzzing vibrations. My students and I thought that my phone was defective!

I turned it off until my review class ended, after which time I realized that my phone was not, in fact, defective. We had received hundreds of orders during my review class! We would continue to receive hundreds of orders over the next several days. And so, Vera Roasting Company was born.

Who has inspired or continues to inspire you to be a great leader? Why?

I dont consider myself to be a great leader, but I like to lead. Ive always liked to take the reins and Ive never been afraid to do so. But leadership should be a shared endeavor. I like to work with others on a journey where a set of shared goals exists. This creates a true team atmosphere where we all look out for each other and enjoy each others accomplishments as much as our own. On a few occasions, Ive seen or worked in an organization that had a decided lack of leadership. It wasnt enjoyable.

How have you used your success to make the world a better place?

Success at Vera Roasting means that we are favorably impacting the lives of our customers. I derive great satisfaction knowing that our customers are improving their cardiovascular health with our coffee. All of our coffees are infused with this beneficial antioxidant. Our Sunshine Blend is additionally infused with vitamin D3 and is helping those with a vitamin D deficiency.

What are your 5 Things I Wish Someone Told Me Before I Started and why? (Please share a story or example for each.)

Traditional advertising is all but dead. This would have saved us time and money!

Packaging is every bit as important as the quality of a product. I was slow to figure this out.

Big retail is expensive. Between distributors, listing fees, buy-backs and the like, retail can be prohibitively expensive for a start-up.

Know your customers. Learning as much about your customerswhy they buy, why they dont, their expectations, etc.is critical.

Dont be afraid to re-brand if needed. Most start-ups begin with a product, not a brand. As one adds more products, customers can get confused. The brand needs to hold it all together. If it doesnt, re-brand to get it right.

What person wouldnt want to work doing something they absolutely love. You are an incredible inspiration to a great many people. If you could inspire a movement that would bring the most amount of good to the most amount of people, what would that be? You never know what your idea can trigger.

There are several potential movements Id love to inspire. I havent given much thought about how one would get such a thing moving, but heres one Ive been thinking about lately:

Id love to see us, as a society, shift away from our pursuit of recognition and instead concern ourselves with the pursuit of excellence. I see so many people at so many levels, from adolescents to young adults to experienced leaders in their respective fields, that work so hard and spend so much time and energy pursuing recognitionwhether it be a pat on the back, an award, a special designation, likes or follows on social media, or some other feather in our cap.

Were so obsessed with recognition that weve forgotten what really mattersexcellence, and in particular, the pursuit of excellence. If we focus on excellence, recognition will come. The pursuit of recognition places the cart ahead of the horse, turns us into shallow human beings, and reinforces some of our least desirable qualities like selfishness, self-centered behavior and greed. The pursuit of excellence, on the other hand, builds self-confidence and reinforces some of our most desirable characteristics like honesty, integrity and respect.

Can you please give us your favorite Life Lesson Quote? Can you share how that was relevant to you in your life?

I still teach organic chemistry to undergraduates at the University of New Hampshire. Many of them wish to pursue careers in chemistry, biochemistry and medicine, to name a few. I am routinely sharing Life Lesson Quotes with these students. Most of these are as relevant to business endeavors as they are to any other pursuit. One of my favorites is

There is a direction correlation between preparation and performance.

So simple, but so important.

Some of the biggest names in Business, VC funding, Sports, and Entertainment read this column. Is there a person in the world, or in the US with whom you would love to have a private breakfast or lunch with, and why? He or she might just see this if we tag them.

Id like to share a meal and discussion with many different people including:

Indra Nooyi. She is, of course, one of the most successful business persons in the world with a wealth of knowledge in multiple industries including the beverage industry. She was trained in chemistry and physics, much like me, before moving into business. And of course, she must have fought her way through male dominated industries. Assuming shed be willing to share some stories, I suspect it would be a great conversation. This aspect of her career is especially interesting to me, not just because I have four daughters, but because Im always interested and intrigued when the underdog prevails. In her case, the underdog not only prevailed, but absolutely kicked a$%&.

Kevin OLeary, a.k.a. Mr. Wonderful. I find his brutally honest, no-nonsense style to be refreshing and I know that he is heavily invested in the wine industry which has some obvious parallels to Vera Roasting Company. I think hed be intrigued by Vera Roasting and Id be intrigued to pick his entrepreneurial brain.

Charles Barkley, a.k.a. the round mound of rebound! I love that Charles Barkley is never afraid to speak his mind, and I find that I agree with his no-nonsense perspective most of the time. Hes very smart, has great instincts and I think wed have a lot to discuss. I also love that he comes from the highly competitive world of professional basketball before moving into entrepreneurial activities.

Thank you for these fantastic insights. We greatly appreciate the time you spent on this.

Excerpt from:

From Avocation To Vocation: How I Turned My Hobby Into A Career With Dr. Glen Miller of Vera Roasting Company - Thrive Global

Studies in rodents have shown that resveratrol, a chemical compound of red wine , has beneficial properties against diabetes, heart diseases and dementia, said the National Institute of Geriatrics (INGER).

Drinking red wine could keep your diabetes, heart diseases and dementia at bay.

The institute explained that the wine has various chemical compounds with antioxidant, anti-inflammatory, cardioprotective and antidiabetic effects. In addition, it favors communication between neurons in certain regions of the brain that improve memory and learning.

One of the most relevant findings, he said, has been to verify that resveratrol activates a protein called Sirtuina1, which regulates other proteins that improve cell functioning, which increases insulin sensitivity, a hormone responsible for decreasing high levels of blood glucose .

In addition, it was observed that red wine or resveratrol protein alone applied in mice suffering from Alzheimers disease improved cognitive status and delayed the normal accumulation of proteins in brain regions that participate in memory control and learning.

However, the attempts that have been made to reproduce the benefits obtained by the treatment of resveratrol observed in animals have been contradictory and unclear in humans.

There is still much to elucidate about wine and more when it comes to confirming or clarifying the beneficial effects of resveratrol on human health, said the National Institute of Geriatrics.

Link:

Red wine could prevent diabetes, heart disease and dementia - The Sen Times Online Newspaper

I once met a couple who was dining at the restaurant where I was pouring wine. When I finished the welcome and the order, and I had placed a glass of red wine in front of the woman, the man said that she had a trick, and implored me to ask her to show it to me. Turns out, she was in recovery from head trauma as a result of a car accident, and shyly, she said she now has the ability to make the molecular structure of the contents of a glass of wine fall apart.

Normally, Im pretty into this kind of paranormal stuff, but I feigned a sort of ennui, lack of interest and gave a less than enthusiastic response, something like: OK, but, um, why would you want to do that? So she proceeded to assume the position, cupping her hands fully and firmly around the glass and thus commenced her practice of destroying the wine. The man then urged me to smell it. As it put my nose to it, he blurted out: See!?

It totally smelled like wine to me.

Bottles in space:

I started thinking about that strange encounter yesterday after a morning scroll through the interwebs pointed me to a news story in the Nov. 5 edition of Decanter Magazine called, Bordeaux Wine Fired Into Space To Test Ageing.

The author of the piece, Chris Mercer, announced: A Northrop Grumman rocket blasted off from a NASA launchpad in Virginia on 2 November, sending the Bordeaux wines into space among 3,700kg of research and supply cargo that also included a zero-gravity baking oven.

He continues with the quip that (sadly): The wines were not part of the International Space Stations Christmas dinner planning; researchers hope to study how radiation in space affects the ageing process.

The wine a case of unspecified red Bordeaux will spend a year aboard the Cygnus spaceship, as part of a joint study by the University of Bordeauxs ISW Wine Institute and Space Cargo Unlimited. The wine will rest untouched (by hand or mouth) at 18 degrees Celsius, which is just above cellar temp, perhaps so the wine can be in a more dynamic temperature for ageing, more exposure to falling apart. Im again thinking of my lady from the story with that apparent skill. An identical case of red Bordeaux will be held here on Earth in the same conditions as a controlled sample.

Mercer quotes Emmanuel Etcheparre, co-founder of Space Cargo Unlimited speaking to Frances SudOuest newspaper: Ageing wine incorporates some of the essential elements of the terrestrial biological ecosystem, such as yeasts, bacteria, crystals, colloids and polyphenols.

The study will focus on how these elements mainly the tannins and other solids involved in ageing wine will behave at zero gravity and with different forces of radiation at play.

Red planet, red wine:

After reading this article, I looked back at some of Mercers other works and found more on the same subject: Wine in space. Seems he is like the Patrick McGovern of wine and space. McGovern, you might know from some of my writing, is a celebrated biomolecular archeologist and anthropologist at the Penn Museum, often called the Indiana Jones of ancient ales, wines, and extreme beverages, uncovering things like the history of fermented drink and the ingredients of the Midas Feast.

In his Decanter Magazine article Could Red Wine Help Power A Mission To Mars? from July 19, Mercer asks that question, though it is not about powering a rocketship with our favorite juice, though that does sound like a really cool idea. Maybe a good use for all of that excess bulk wine just sitting around Napa, Sonoma and the Central Valley at the moment.

Rather, the study looks to a key compound in red wine as a possible superfood or nutritional support for long journeys into space. The compound in question is resveratrol, which has long been thought to be the healing grace of red wine, blessing human imbibers with everything from healthy skin and hearts to longevity. For this particular study, the focus is the possibility that resveratrol may help astronauts (and perhaps future civilian space travelers) maintain bone and muscle mass while on Mars.

Not so fast, as Mercer again spoils our wildest dreams of a Bordeaux-and-Burgundy party in space: However, its unlikely that astronauts will be loading up their space shuttle with Chteau Anglus or Romane-Conti for a daily toast on the red planet. The amount of red wine needed to get one gram of resveratrol per day would be anywhere from 505 to 2,762 liters of red wine. The participants in the study, again, sadly, will be administered resveratrol in concentrated supplements.

No red wine pills here, and as I type, the wine is piling up, with Thanksgiving just around the corner. Ill be blowing that horn of plenty in the next few editions of Wine Reveals Truth.

Cheers! Remember, wine reveals truth.

Drew Stofflet lives in Carbondale. Correspond with him at drew.stofflet@gmail.com

Originally posted here:

Paranormal wine: Space and wine x2 - Aspen Daily News

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Resveratrol Market Strategies and Insight Driven Transformation 2019-2027 - The Denton Chronicle

Propelled to fame from a multitude of studies on the phytochemical properties of plants, resveratrol more than lives up to its reputation. Experts have called this unique antioxidant a fountain of youth for its effectiveness against a variety of age-related conditions.

Researchers first became interested in resveratrol when studying the French paradox" in the late 1980s: French diets were high in fatty foods, yet overall, French people experience low rates of heart disease. Scientists set out to discover why.

Soon, they found a compound in red wine, which was then isolated from the skin of grapes. The next task was to figure out how it worked in the body.

Since that time of first discovery, studies have revealed the many benefits of resveratrol, including boosting heart health, supporting normal brain function, and promoting healthy aging. The compound has powerful antioxidant effects, thereby supporting health at the cellular level.

In this post, we're going to explore 10 facts about resveratrol including what it is, where you can find it, and whether you should get it regularly from your diet.

Resveratrol is a phenolic compound called a stilbene; plants produce these in response to injury, infection, fungal attack, or ultraviolet radiation. The very compounds that protect plants can also protect you.

Most phenols, including stilbenes like resveratrol, are brightly colored, aromatic, and good for your health.

Most stilbenes come from berries and grapes. They have strong antioxidant benefits, counteracting the daily "oxidative stress" that damages cells.

Resveratrol, one stilbene compound, promotes bone, cardiovascular, and liver health. This unique nutrient also supports healthy aging, improves cognitive function, and normalizes hormone production.[1]

Resveratrol exists primarily in two forms, a trans and a cis form. These forms are isomers compounds with the same number and types of atoms but arranged in different structures.

Cis and trans isomers, specifically, have atoms joined in the same order, but in a slightly different geometric configuration. That change makes cis isomers polar carrying an electrical charge and water-soluble, and trans molecules non-polar and fat-soluble.

This gives them quite different properties, including bioavailability essentially, the degree and rate at which your body absorbs them after going through the digestive system, liver, and bloodstream. Below, we break down the differences plus describe a third form.

Because trans-resveratrol is fat-soluble, it binds to lipoproteins (fat-containing proteins), which allows it to easily cross cell membranes. However, the body metabolizes and eliminates it quickly, so its bioavailability is relatively low at around 25 percent but higher than cis-resveratrol.

A double bond isomer of trans-resveratrol, this molecule is polar and soluble in water, so it less easily enters cells and is less easily used by the body. You will sometimes find it as a filler in poor quality, less pure supplements.

This form is found in wine, but also in your gut after you consume trans-resveratrol. The probiotic microbes in your digestive tract interact with trans-resveratrol, metabolizing it into dihydro-resveratrol.

Resveratrol is perhaps best known for its positive effects on heart health, but studies have also linked it to a number of other impressive health benefits.

Let's explore 10 ways resveratrol promotes health and longevity.

Chances are, you've heard that drinking red wine is good for cardiovascular health. You may not know that experts believe resveratrol is the ingredient responsible for this positive effect on your heart.

Resveratrol helps normalize levels of bad cholesterol," or low-density lipoprotein (LDL).[2] Keeping bad cholesterol at healthy levels protects you against the plaque buildup in your arteries that can lead to heart attack or stroke.

Additionally, resveratrol helps maintain normal blood pressure. In particular, it relaxes blood vessels, which keeps your systolic blood pressure at normal levels; systolic is the upper number on your blood pressure reading, and it tells you the tension in your arteries as blood gets pumped through.[3]

Your blood pressure and cholesterol tend to gradually rise with age, and taking this healthy antioxidant supplement may help people enjoy their golden years with a happy heart.

Want a brain boost? Help is on the horizon. Some experts consider resveratrol a nootropic, a substance that helps enhance memory and brain health.

Unlike some other antioxidants, trans-resveratrol crosses the blood-brain barrier, where it can directly enter into brain cells. This allows for positive, direct support for neural health including the brain plus the central and peripheral nervous systems.

Researchers have found that resveratrol increases blood flow to the brain.[4] When you have increased blood flow, you get more oxygen, glucose, and other nutrients to your brain. This, in turn, helps maintain "cognitive function" the ability to think clearly, have a healthy memory, and stay focused.[5]

One study of 23 older adults observed significant improvements in memory among participants taking resveratrol.[6] The compound offered the additional benefit of improving the study participants glucose metabolism and concluded that resveratrol could help maintain brain health as we age.[6]

Reducing calories by 30 percent, whether by intermittent fasting or simply reducing how much you eat, supports health and longevity. Caloric restriction and fasting can advance longevity by 40 percent or more in some species. When you restrict calories, the body goes into a defensive state that has long helped humans and other living organisms survive adversity fascinating!

Resveratrol mimics the health effects of fasting or calorie-reduction, which may help you lose weight. It does this by stimulating adiponectin creation, the same hormone that increases in individuals practicing caloric restriction.[7]

Adiponectin promotes metabolic and cardiovascular health through weight loss, lipid metabolism, and regulation of blood sugar levels.

In other words, adiponectin helps maintain normal blood sugar, helps your heart, and helps you lose weight. Because resveratrol stimulates adiponectin, you get the benefits of both.

As an antioxidant, resveratrol counteracts some of the damage that free radicals cause to your cells. Your body is constantly exposed to free radicals from various sources, ranging from chemical pesticides in your food and water to the sun's UV rays or just from normal aging.

Oxidative stress is an imbalance between free radicals that enter your body from the environment and the antioxidants in your body that work to eliminate them.

This oxidative stress is responsible for some of the things that go along with your body's age-related changes. Lucky for us, studies have noted resveratrol's ability to reduce oxidative stress from free radical damage.

One 2011 study evaluated how 20 human volunteers responded to resveratrol and placebo (a sugar pill) over six weeks. Those who received resveratrol had reduced oxidative stress and lower levels of swelling and redness commonly associated with a number of age-related diseases.[8]

In another study, resveratrol eliminated oxidative stress and had neuroprotective effects.[9]

As men age, their testosterone levels often decrease. Low testosterone levels can have a negative impact on a man's physical and mental well-being.

Research indicates resveratrol positively affects reproductive function in men. Studies have found it can increase blood testosterone levels.[10]

The study also found resveratrol supplementation helps support normal, healthy fertility in men. While this is good news for men of reproductive age, older men could benefit as well. Testosterone strengthens bones, increases muscle mass, and encourages a positive outlook in men.

Women who consume resveratrol appear to enjoy benefits, as well, particularly older women. At menopause, estrogen levels decline rapidly. Research shows that resveratrol supplementation could help stabilize and normalize estrogen and other hormones.

A small study of postmenopausal women taking resveratrol daily for 12 weeks reported improvements in estrogen metabolism. Resveratrol also promoted normal levels of SHBG (sex hormone-binding globulin).[11]

SHBG enables the body to make better use of the hormones already present. In essence, resveratrol may support hormone balance, which, in turn, helps heart health and bone health.[12]

Though it may seem counter-intuitive that an ingredient found in wine could be helpful for the liver, research shows that it is. But you don't need to drink alcohol to consume resveratrol and enjoy the benefits it offers.

Conditions that affect the liver are among the most common health issues in the Western world.[13] Resveratrol may protect the liver and promote normal liver function.

Resveratrol appears to support the liver.[14] It protects the liver by helping the body regulate oxidative stress, reducing redness and swelling, and alleviating cell death in the liver.[15]

If you're hitting the gym and not seeing the improvement you'd like, resveratrol may help.

Normal exercise causes oxidative stress, and resveratrol's antioxidant status appears to help muscles recover more quickly. This effect works both after the strain of exercise and after lack of use such as after an injury or hospitalization.[16]

Resveratrol supplementation can also enhance your exercise performance. In one study, resveratrol not only boosted how efficiently rats ran on a treadmill by 21 percent, but it also helped their bodies break down fat and strengthened skeletal muscle.[17]

As we get older, muscle mass and strength decrease. Aging muscles tend to heal and grow more slowly than they do in our youth. Resveratrol appears to improve muscle mass and muscle regeneration in older adults, especially when used alongside exercise.[18]

While most resveratrol research focuses on taking it internally, some studies have looked at how applying it to the skin shields your skin from environmental pollutants and harmful UV rays.

Dermatology research has shown that resveratrol has 17 times more antioxidant power than some popular and expensive anti-wrinkle creams.[19]

If acne is a concern, resveratrol may improve the appearance of your complexion. Applied topically, this compound inhibits the growth of harmful organisms on the skin. It also calms the redness and swelling that acne often causes.[20]

Last but not least, resveratrol boosts collagen production, smooths out fine lines and wrinkles, and improves your skin's appearance.[21]

Joint soreness can have a tremendous impact on your life and prevent you from engaging in activities that you enjoy.

Thanks to its powerful antioxidant properties, resveratrol may support sore joints, offering some relief. One study showed that resveratrol significantly helped people with knee discomfort feel better.[22]

In another study, researchers found that injecting resveratrol into the knee joints may stabilize cartilage that is uncomfortable from arthritis.[23]

Resveratrol can reduce redness and swelling in joints, and may even protect your joints from further damage.[24]

You can find resveratrol in several plant foods, particularly berries, and you can buy it in supplements.

Resveratrol is abundant in the skin of grapes, which is why we find it in wine most notably red wine. You will not find the compound in the flesh or seeds of grapes, so while grape seed extract is also a powerful antioxidant, don't look to it to find resveratrol.

Scientists have found resveratrol in several other brightly-colored fruits and berries, such as:

In some Asian countries, people drink Itadori tea, a traditional herbal supplement believed to ward off heart disease and stroke. This source of resveratrol can cause diarrhea and cramping.

Only 25 percent of resveratrol from dietary sources is bioavailable because it gets metabolized quickly.[25]

Dietary intake from naturally-occurring resveratrol averages 0.3 to 1.5 mg per day if one consumes these foods.

Resveratrol supplements typically contain a much higher concentration of the compound, so more is available to cells. Some of the lower quality, cheaper options contain equal amounts of the trans and cis forms. Be sure to check labels and aim to use supplements that have a higher concentration of trans-resveratrol, preferably 99 to 100 percent. Not only is this form more easily absorbed by the body, but it also offers better results for your health.

Many resveratrol supplements come from Japanese knotweed roots. While plant-derived supplements are often beneficial, this plant's roots contain a substance called emodin, a laxative. While manufacturers try to remove the emodin, even small amounts can cause cramping and diarrhea. The extraction process for these supplements may also introduce harmful solvents, like hexane and polyaromatic hydrocarbons (PAHs).

Some companies sell fermented resveratrol, which comes from yeast, and does not contain emodin. However, your best option is Resvida. As the most potent, purest, and most scientifically researched form of trans-resveratrol, Resvida contains no emodin and has maximum bioavailability.

Resveratrol is generally safe for consumption with no serious adverse effects according to numerous studies,[26] and it is "generally recognized as safe" (GRAS) according to the U.S. Food & Drug Administration. When taken in higher servings, or if you take supplements and extracts derived from Japanese knotweed, rather than Resvida, some people may experience mild to moderate gastrointestinal effects, including nausea, gas, and diarrhea.

Resveratrol may interact with some medications, so speak with your healthcare provider before considering a resveratrol supplement if you are currently taking medication.[27] If you are pregnant or nursing, do not take resveratrol supplements, as its safety has not been thoroughly tested on pregnant women.

Many people are looking for antioxidant supplements that soothe irritation and discourage harmful organisms. Resveratrol offers all of these.

Found in the skin of grapes, berries, dark chocolate, and dietary supplements, resveratrol has a number of health benefits. Trans-resveratrol is the most effective form because it easily crosses cell membranes, as well as the blood-brain barrier.

Resveratrol promotes vitality and wellness, encourages longevity, and even helps maintain health for age and lifestyle-related conditions.

This unique nutrient supports brain health, increases endurance, discourages weight gain, and helps balance hormones for both women and men. Not only that, resveratrol also has a positive impact on heart health, protects the liver, alleviates joint pain, and even helps improve your skin's appearance. The best, most-tested resveratrol supplement is Resvida, the purest, most scientifically researched form of the supplement.

What are your thoughts on resveratrol? Do you take antioxidant supplements? Please let us know your opinions in the comments!

Results may vary. Information and statements made are for education purposes and are not intended to replace the advice of your doctor. If you have a severe medical condition or health concern, see your physician.

Read the original here:

10 Resveratrol Benefits for Heart, Mind, & the Fountain of Youth

Given the opportunity to live much longer lives, many of us might feel less than thrilled at the prospect. After all, you might think, who would want to live an extra 20 years dealing with arthritis, dementia, or heart problems?

But what if those years could be filled with youthful vigor or at least middle-aged comfort?

The ability to reverse, or slow down, the degenerative processes that come with increased age has been a long-held human aspiration. Indeed, it has provided a consistent focus for decades of scientific research on aging.

But it is only in the last 10 years that the replacement of palliative treatments (which suppress the symptoms of age-related diseases) with genuine anti-degenerative medicines (which prevent and repair) has become more than a pipe dream.

This paradigm shift stems from recent research that shows that just a few biological root causes underpin almost all the diseases of old age. Such a discovery is an opportunity to address a wide range of illnesses simultaneously with treatments that target single biological mechanisms. For the first time, aging has become druggable.

One leading cause of age-related changes, including illness, is known as cell senescence. This is a consequence of evolution that only really comes into play when organisms outlive their normal reproductive age, or are subjected to a very damaging environment. When cells become senescent, they can no longer divide and typically behave in a way that damages the tissue around them.

For many years, much of the gerontological community had considered cell senescence to be a symptom rather than a cause of age-related decline. However, recent groundbreaking research showed that removing senescent cells from mice not only prevents normal aging, but actually reverses many of the symptoms. This proof that senescent cells cause aging finally provides us with the potential to develop a cure.

Follow-up work has revealed that the positive effects of senescent cell removal in mice extend to myocardial infarction (which causes heart attacks), Alzheimers disease, and metabolic dysfunction. The challenge now is to translate these findings to treatments in aging humans.

To that end, major investors have now joined researchers in the search for ways to kill, remove, or rejuvenate senescent cells. And they have made exciting progress.

For example, when combined, dasatanib (a leukaemia drug) and quercetin (a natural product found in vegetables), show improved health and life span in mice. And early results from clinical trials of this combination have demonstrated the first-ever alleviation of physical dysfunction in patients with idiopathic pulmonary fibrosis, a progressive degenerative lung disease with no current effective treatment.

The list of common side-effects associated with dasatanib means it would likely be restricted to only the most seriously ill patients. But the trials give hope for medicinal chemists to develop a more palatable second generation of similar drugs.

An alternative strategy is the rejuvenation of senescent cells. Resveratrol, found in red wine and chocolate, was shown to be able to rejuvenate senescent cells in the lab, restoring their molecular fingerprint and growth to that of normal youthful cells.

Importantly, this work also demonstrated that small synthetic modifications were able to tune the effects achieved again demonstrating that a medicinal chemistry approach to the problem is highly likely to be successful.

Elsewhere, Fisetin, a natural product found in strawberries, apples, and onions, was recently shown to confer both improvements in health and a reduction in the senescent cell load in old mice. It is now also the subject of clinical trials.

Interestingly, Fisetin also interacts with other key aging mechanisms, such as nutrient sensing the biological mechanism that underlies the well-known health and life span-increasing effects of calorie restriction.

It is not yet clear whether this is a new kind of super-therapeutic that simultaneously targets more than one cause of aging, or whether it will reveal a new piece of the jigsaw that allows us to integrate the known paths to morbidity into a coherent whole.

The research conducted so far, just using natural products and existing drugs, has shown unequivocally that small molecules can produce a broad spectrum of anti-degenerative effects.

Drug discovery for aging is moving beyond its infancy, and preventative medicine that will revolutionize 21st-century healthcare is now genuinely possible. Now we need to add synthetic medicinal chemistry to the mix to develop safe and effective drugs that will help us all into a healthier and more active future.

This article was originally published on The Conversation by Lizzy Ostler. Read the original article here.

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One type of food could help reverse aging, thanks to resveratrol - Inverse

How do the French eat more fat, sugar and rich foods, plus drink more wine, but still have less heart health issues? The answer to this puzzling question, commonly known as the french paradox, is believed to be due to a higher intake of a specific phytonutrient called resveratrol, found naturally in superfoods like red wine. Like other antioxidants and phytonutrients, such as lycopene found in tomatoes or lutein found in carrots, resveratrol is a powerful compound that regenerates the body all the way at the cellular level.

Research published over the past several decades in many medical journals, including the European Journal of Food Pharmacology andAmerican Journal of Hypertension,found that resveratrol (in this case from red wine) decreases the risk of heart disease among other common health concerns. Although he might not have known exactly how wine was able to promote better health, even Plato promoted the health perks of drinking it in moderation. Hes been quoted as saying, Nothing more excellent or valuable than wine was ever granted by the gods to man. (1)

In case youre wondering, you dont have to be a wine drinker to benefit from resveratrol. Other sources include deeply- olored berries and real dark chocolate/cocoa. Along with helping to keep arteries clear from plaque buildup and protecting an aging heart, this phytonutrienthas many other health benefits too including reducing inflammation, potentially helping to prevent obesity and protecting cognitive health among the elderly.

Resveratrol is a polyphenic bioflavonoid antioxidant thats produced by certain plants and found in foods and drinks that are known to halt the effects of aging. Resveratrol is classified as aphytoestrogen because of its ability to interact with estrogen receptors in a positive way. Plants that produce resveratrol and other types of antioxidants actually do so partly as a protective mechanism and response to stressors within their environments, including radiation, the presence of insects or other predators, injury, and fungal infections. Today, resveratrol is believed to be one of the most potent polyphenols and strongest protectors against symptoms associated with aging andfree radical damage.

Studies show that the most naturally abundant sources of resveratrol (not to mention many other protective phytonutrients, vitamins and minerals) are plants, including the skin of red grapes, red wine, raw cocoa, and dark berries, such as lingonberries, blueberries, mulberries and bilberries. Red wine is probably the best known source, mostly due to its high levels thanks to the fermentation process that turns grape juice to alcohol. During production of red wine, grape seeds and skins ferment in the grapes juices, which have positive effects on levels and availability of resveratrol.

The benefits of resveratrol were first discovered when researchers found that yeast and other microbes, insects and animals fed resveratrol experienced an increased life span as a result. Various studies continued to confirm its amazing anti-aging benefits, demonstrated in studies conducted on fruit flies, fish, mice and nematode worms, all of which lived longer compared to control groups that were not treated with this phytonutrient.

Resveratrol is a powerful antioxidant that neutralizes free radicals produced during everyday bodily functions, such as eating and exercise. Free radical damage is accelerated due to poor lifestyle habits like smoking, eating an unhealthy diet, and in response to environmental pollution and toxicity. If left unchecked, free radicals can damage cells and are thought to be a cause of life-threatening diseases andearlier death. Consuming plant foods high in antioxidants and phytonutrients has been shown to offer antioxidative, anticarcinogenic and antitumor benefits that protect adults from many age-related diseases. (2)

According to research published by the Department of Pharmacology at the University of Seville in Spain, One of the most striking biological activities of resveratrol soundly investigated during the late years has been its cancer-chemopreventive potential. In fact, recently it has been demonstrated that it blocks the multistep process of carcinogenesis at various stages: tumor initiation, promotion, and progression.

Its believed the mechanisms for its cancer-protecting activities involves downregulation of the inflammatory response through inhibition of synthesis and release of pro-inflammatory mediators, among other activities. (3)

Because of its anti-inflammatory activity, resveratrol has been shown to offer protection against atherosclerosis (thickening of the arteries that cuts off blood flow), high LDL bad cholesterol, formation of blood clots and myocardial infraction. Consuming more has also been shown to help improve circulation and have beneficial effects on glucose and lipid metabolism in some with higher risk for metabolic syndrome. (4)

Itadori tea, one significant source of resveratrol, has long been used in Asian countries, including Japan and China, as a traditional herbal remedy for preventing heart disease and strokes.

Resveratrol is particularly unique as its antioxidants can cross the blood-brain barrier to protect the brain and the nervous system, unlike other antioxidants. Recent studies done by researchers at the Nutrition Research Center at Northunbria University in the U.K. showed that resveratrol noticeably increased blood flow to the brain, suggesting a considerable benefit to healthy brain function and neuroprotective effects.

This means consuming more can increase protection against cognitive/mental problems, including Alzheimers, dementia and others. Other study findings, such as results published in the Journal of Agricultural Food Chemistry, demonstrated that even a single infusion of resveratrol could elicit neuroprotective effects on cerebral (brain) neuronal loss and damage. (5) This resulted from increased free radical scavenging and cerebral blood elevation due to resveratrols effects.

Findings from animal studies have found that resveratrol exerts beneficial effects on rodents fed a high-calorie diet, helping prevent fat storage and regulating insulin levels. (6) Others research has shown that resveratrol may help reduce body weight and adiposity in obese animals, which some experts believe is due to activating the SIRT1 gene thats believed to protect the body against the effects of obesity.

Its not totally clear how this translates to humans consuming foods or drinks like wine and berries, but studies have found links between adults eating balanced diets that include moderate amounts of wine and healthier body weights.

Animal studies involving diabetic rats have demonstrated that resveratrol may be able to reduce hyperglycemia and may also possibility be of use in preventing and/or treating both obesity and diabetes. Resveratrol may be helpful for those with diabetes and prediabetes byreducing complications (like nerve damage and damage to the heart) and helping manage insulin levels. Its known that this phytoestrogenpositively affects insulin secretion and blood insulin concentrations, according to animal studies. (7)

As you can tell from all the benefits described above, resveratrol and sources that provide it, including red wine, are more than just powerful heart-protectors. Theyre also strong brain-boosters, among many other things. People use resveratrol for all sorts of anti-aging benefits, considering research suggests that itcan help:

Should You Take Resveratrol Supplements?

Because the FDA does not regulate supplements, many health authorities are not convinced that taking resveratrol supplements or extract will have much payoff. As with all herbs and extracts, you cant be sure exactly what youre getting and how effective the product may be.

Dosage recommendations vary depending on your current health and symptoms, but most resveratrol supplements are typically taken in about 250 to 500 milligrams/day dosages. Its important to point out that this is generally lower than the amounts that have been shown to be beneficial in studies, but its not clear if taking very high doses is safe. Some adults choose to consume up to two grams daily (2,000 milligrams). (8) According to the New York Academy of Sciences, studies have found resveratrol to be safe and reasonably well-tolerated at doses of up to five grams per day, but this shouldnt be taken without speaking with your doctor. (9)

Its possible, however, to experience mild to moderate side effects at higher doses, so experts recommend starting with less until further studies demonstrate any added benefit of taking more. Resveratrol supplements may potentially interact with blood thinners like warfarin (Coumadin) and NSAID pain relievers (like aspirin or Advil), so be sure not to mix these.

Resveratrol works by modifying inflammation in the body, in addition to having other positive effects on hormone production, blood circulation and fat storage. Studies demonstrate that itspecifically seems to work in some of the following ways:(10)

Now you know the benefits of resveratrol in your diet, you may be wondering what the best source of this compound is. Below are the best foods and beverages to add to your diet (albeit in moderation) in order to consume more resveratrol:

Different plants supply various forms of resveratrol. For example grapes, peanuts and Itadori tea contain mainly trans-resveratrol glucosides. Red wine is primarily a source of the aglycones cis- and trans-resveratrol. Studies show that both Itadori tea and red wine supply relatively high concentrations of resveratrol compared to most other foods. Itadori tea is a good option for people who avoid drinking alcohol or for children.

Although we have mentioned that red wine and cocoa are two of the best sources of resveratrol, unfortunately a diet of dark chocolate and red wine may be decadent but ultimately very unhealthy if you overdo it. The best way to obtain the benefits of resveratrol is through balance and moderation. I recommend consuming wine in small amounts, about one glass per day or less; according to most research, up to two glasses daily for men and one per day for women hasnt been shown to cause any health concerns. If you do choose to take resveratrol supplements, still aim to consume antioxidants naturally from a healthy diet, including a variety of fresh plant foods.

While a large body of evidence has already suggested that resveratrol has many benefits, many experts feel that before we can promote drinking more wine or taking supplements to all adults, additional research is still needed. Overall theres support for itspositive attributes, but data is still needed to confirm its effectiveness for prevention of actual diseases in humans. Its still not completely known how different people react to resveratrol and if some benefit more than others. For example, people with existing cases of diabetes or metabolic defects may need to take higher doses than mostly healthy adults to get the same effects. Talk to your doctor if you plan on taking supplements and are already on other medications.

Overall, most of the benefits of resveratrol have been shown in animal studies and at high dosages. Harvard School of Public Health points out, The dose of resveratrol administered in experiments is always much higher than youd normally consume in a daily diet. You would need to drink a hundred to a thousand glasses of red wine to equal the doses that improve health in mice. (11)

That being said, resveratrol is not a cure-all and means to living a longer, disease-free life. It may be one piece of the puzzle, but the bottom line is that it probably shouldnt motivate you to drink more wine than you already are.

From the sound of it, you might think leaky gut only affects the digestive system,but in reality it can affect more. Because Leaky Gut is so common, and such an enigma,Im offering a free webinar on all things leaky gut.Click here to learn more about the webinar.

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Resveratrol Benefits, Resveratrol Sources & More - Dr. Axe

Resveratrol is a polyphenol antioxidant found in Tiger Cane (Japanese Knotweed) and the skin of red wine grapes. Its wellness benefits can include:

Resveratrol is an antioxidant compound that came to prominence in the early 1990s due to the discovery of its presence in red wine. As a health-promoting compound found in one of the worlds most popular beverages, it captured the attention of millions. Its promise was reinforced by some experts who suggested it may account for the French Paradox, the fact that French populations enjoy relatively good heart and cardiovascular health despite their high intake of saturated fats and red wine.**

Research appears to support this compounds benefits for heart and cardiovascular health. As a highly active antioxidant, it helps to reinforce the hearts resistance to cell-damaging free radicals. This may be critical because the heart, which pumps 1,800 gallons of blood each day, is under constant oxidative stress from free radicals. Its antioxidant protection extends to the circulatory system, where it helps protect LDL cholesterol from being oxidized. Oxidized LDL raises risk of cardiovascular problems; resveratrol may promote a healthy balance of blood lipids. It protects the blood vessels, helping to keep them flexible and healthy, and modulates inflammation throughout the cardiovascular system, helping with a common risk factor for heart health issues.**

This red wine compound supplies biological activity that has been linked to anti-aging benefits, starting with its ability to neutralize age-accelerating free radicals throughout the body. Perhaps more intriguing, it is believed to mimic the effects of calorie restriction, which is associated with longevity. Very early research has suggested that it even activates a longevity gene in yeast that extends lifespan. These benefits, along with its ability to promote cognitive health and mental clarity, have helped position the antioxidant as one of the leading nutrients for anti-aging wellness.**

Supplements are typically presented as capsules, coated caplets or tablets. They may source resveratrol from red wine grape skin or Tiger Cane (Japanese Knotweed). These supplements are known for their potency, supplying in a single serving the same antioxidant activity that is found in dozens of glasses of red wine.**

There is no set dosage, but the nutrient is often supplied in serving sizes ranging from 100 mg to 500 mg. Be sure to talk with your doctor before adding this supplement, or any other supplements, to your daily health regimen.**

Original post:

Resveratrol Supplements | Resveratrol Benefits | Piping ...

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71. Retraction Watch

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Excerpt from:

Resveratrol Extract Powder - Z Natural Foods

Resveratrol is LIKELY SAFE when used in the amounts found in foods, and when taken by mouth in doses up to 250 mg daily for up to 3 months. Higher doses of up to 900 mg have been taken for up to 2 days. Resveratrol has also been applied to the skin safely for up to 30 days. Special Precautions & Warnings: Pregnancy and breast-feeding: Resveratrol is LIKELY SAFE when used in amounts found in some foods. However, during pregnancy and breast-feeding, the source of resveratrol is important. Resveratrol is found in grape skins, grape juice, wine, and other food sources. Wine should not be used as a source of resveratrol during pregnancy and breast-feeding.

Bleeding disorders: Resveratrol might slow blood clotting. In theory, resveratrol might increase the risk of bleeding in people with bleeding disorders.

Hormone-sensitive condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Resveratrol might act like estrogen. If you have any condition that might be made worse by exposure to estrogen, don"t use resveratrol.

Surgery: Resveratrol might increase the risk of bleeding during and after surgery. Stop using resveratrol at least 2 weeks before a scheduled surgery.

Read more here:

Resveratrol: Uses, Side Effects, Interactions, Dosage, and ...

If you've heard that red wine can help lower cholesterol, chances are you've heard of resveratrol the much-hyped plant compound found in red wine.

But beyond being a healthful part of red wine and other foods, resveratrol has health-boosting potential in its own right.

In fact, resveratrol supplements have been linked to many exciting health benefits, including protecting brain function and lowering blood pressure (1, 2, 3, 4).

This article explains what you need to know about resveratrol, including seven of its main potential health benefits.

Resveratrol is a plant compound that acts like an antioxidant. The top food sources include red wine, grapes, some berries and peanuts (5, 6).

This compound tends to be concentrated mostly in the skins and seeds of grapes and berries. These parts of the grape are included in the fermentation of red wine, hence its particularly high concentration of resveratrol (5, 7).

However, much of the research on resveratrol has been done in animals and test tubes using high amounts of the compound (5, 8).

Of the limited research in humans, most has focused on supplemental forms of the compound, in concentrations higher than those you could get through food (5).

Because of its antioxidant properties, resveratrol could be a promising supplement for lowering blood pressure (9).

A 2015 review concluded that high doses may help reduce the pressure exerted on artery walls when the heart beats (3).

That type of pressure is called systolic blood pressure, and appears as the upper number in blood pressure readings.

Systolic blood pressure typically goes up with age, as arteries stiffen. When high, it's a risk factor for heart disease.

Resveratrol may accomplish this blood-pressure-lowering effect by helping to produce more nitric oxide, which causes blood vessels to relax (10, 11).

However, the authors of that study say more research is needed before specific recommendations can be made about the best dose of resveratrol to maximize blood pressure benefits.

Several studies in animals have suggested that resveratrol supplements may change blood fats in a healthy way (12, 13).

A 2016 study fed mice a high-protein, high-polyunsaturated fat diet and also gave them resveratrol supplements.

Researchers found the average total cholesterol levels and body weight of the mice decreased, and their levels of "good" HDL cholesterol increased (13).

Resveratrol seems to influence cholesterol levels by reducing the effect of an enzyme that controls cholesterol production (13).

As an antioxidant, it also may decrease the oxidation of "bad" LDL cholesterol. LDL oxidation contributes to plaque buildup in artery walls (9, 14).

In one study, participants were given grape extract that had been boosted with extra resveratrol.

After six months of treatment, their LDL had gone down by 4.5% and their oxidized LDL had gone down by 20% compared to participants who took an unenriched grape extract or a placebo (15).

The compound's ability to extend lifespan in different organisms has become a major area of research (16).

There's evidence that resveratrol activates certain genes that ward off the diseases of aging (17).

It works to achieve this in the same way as calorie restriction, which has shown promise in lengthening lifespans by changing how genes express themselves (18, 19).

However, it's not clear if the compound would have a similar effect in humans.

A review of studies exploring this connection found that resveratrol increased lifespan in 60% of the organisms studied, but the effect was strongest in organisms that were less related to humans, such as worms and fish (20).

Several studies have suggested that drinking red wine can help slow down age-related cognitive decline (21, 22, 23, 24).

This may partly be due to the antioxidant and anti-inflammatory activity of resveratrol.

It seems to interfere with protein fragments called beta-amyloids, which are crucial to forming the plaques that are a hallmark of Alzheimer's disease (21, 25).

Additionally, the compound may set off a chain of events that protects brain cells from damage (21).

While this research is intriguing, scientists still have questions about how well the human body is able to make use of supplemental resveratrol, which limits its immediate use as a supplement to protect the brain (1, 2).

Resveratrol has been shown to have several benefits for diabetes, at least in animal studies.

These benefits include increasing insulin sensitivity and preventing complications from diabetes (26, 27, 28, 29).

One explanation for how resveratrol works is that it may stop a certain enzyme from turning glucose into sorbitol, a sugar alcohol.

When too much sorbitol builds up in people with diabetes, it can create cell-damaging oxidative stress (30, 31).

Here are a few more benefits resveratrol may have for people with diabetes (28):

Resveratrol may even provide more benefits for people with diabetes than those who don't have it. In one animal study, red wine and resveratrol were actually more effective antioxidants in rats with diabetes than in rats who didn't have it (32).

Researchers say the compound could be used to treat diabetes and its complications in the future, but more research is needed.

Arthritis is a common affliction that leads to joint pain and loss of mobility (33).

Plant-based supplements are being studied as a way to treat and prevent joint pain. When taken as a supplement, resveratrol may help protect cartilage from deteriorating (33, 34).

Cartilage breakdown can cause joint pain and is one of the main symptoms of arthritis (33).

One study injected resveratrol into the knee joints of rabbits with arthritis and found that these rabbits suffered less damage to their cartilage (34).

Other research in test tubes and animals has suggested that the compound has potential to reduce inflammation and prevent damage to joints (33, 35, 36, 37).

Resveratrol has been studied, especially in test tubes, for its ability to prevent and treat cancer. However, results have been mixed (30, 38, 39).

In animal and test-tube studies, it has been shown to fight several kinds of cancer cells, including gastric, colon, skin, breast and prostate (40, 41, 42, 43, 44).

Here's how resveratrol may combat cancer cells:

However, since the studies so far have been carried out in test tubes and animals, much more research is needed to see if and how this compound might be used for human cancer therapy.

No major risks have been revealed in studies that have used resveratrol supplements. Healthy people seem to tolerate them well (47).

However, it should be noted that there aren't enough conclusive recommendations about how much resveratrol a person should take in order to get health benefits.

And there are some cautions, especially regarding how resveratrol could interact with other medications.

Since high doses have been shown to stop blood from clotting in test tubes, it's possible it could increase bleeding or bruising when taken with anti-clotting drugs, such as heparin or warfarin, or some pain relievers (48, 49).

Resveratrol also blocks some enzymes that help clear certain compounds from the body. That means some medications could build up to unsafe levels. These include certain blood pressure medications, anxiety meds and immunosuppressants (50).

If you currently use medications, then you may want to check with a doctor before trying resveratrol.

Lastly, it's widely debated how much resveratrol the body can actually use from supplements and other sources (51).

However, researchers are studying ways of making resveratrol easier for the body to use (6, 52).

Resveratrol is a powerful antioxidant with great potential.

It's shown promise regarding a variety of health conditions, including heart disease and arthritis. However, clear dosage guidance is still lacking.

More:

7 Health Benefits of Resveratrol Supplements

Delicious, juicy black grapes are simply irresistible when it comes to taste. And the best part is that these small berries are packed with an incredible amount of nutrients as well. That is why black grapes have been much in demand amongst Epicureans for more than 6,000 years when they were first cultivated in west Asia and parts of Europe. In fact, it is said that black grapes are the oldest cultivated fruit in the world. Black grapes were introduced in India way back in the 12th century by traders from Iran and Afghanistan. Whileblack grapes (Vitis vinifera) are mostly used to make wine, they are also relished as a fruit and as a key ingredient in jams, sauces, preserves and compte.

Black grapes are an essential fruit crop for Indian farmers as it is very profitable. Hence, almost 79.6 thousand hectares are under grape cultivation in India with the major chunk being grown in Maharashtra, Andhra Pradesh, Karnataka, Tamil Nadu. Black grapes in India are traditionally harvested by hand during February-April. Much of the black grape harvest is used to make red wine where the pulp of red or black grapes is fermented along with the skins so that the red pigmentation and the goodness of antioxidants (resveratrol) are retained.

Studies have shown that eating black grapes, and its products may help protect your heart from cardiovascular disease and heart attacks. Resveratrol and quercetin, compounds found in black grapes, reduce atherosclerosis risk and give protection against the damage caused by high LDL cholesterol levels in the bloodstream.

These polyphenols, like resveratrol, are antioxidants that reduce inflammation by preventing platelet build-up. These amazing compounds in black grapes are also useful in preventing metabolic syndrometypified by high blood pressure, blood sugar, abdominal fat, triglycerides and low HDLthat cause cardiovascular diseases, stroke and Type 2 diabetes.

Black grapesare rich in heart-healthy fibre and potassium and regulate blood pressure. Cardiologists recommend eating a high-potassium-low-sodium diet to lower blood pressure-related complications. Potassium-rich foods also protect you against stroke, loss of muscle mass, and reduced bone mineral density. Black grapes are a great source as they contain 191mg of potassium in 100 grams.

Tip: Black grapes help in boosting one's immunity.

Black grapes contain carotenoids called Lutein and Zeaxanthin that prevent oxidative stress to the retina and other degenerative changes. According to a University of Miami study, eating a diet rich in grapes lowers inflammation that causes macular degeneration.

Tip: Compounds like flavans, anthocyanins, flavonols, and stilbenes in black grapes fight inflammation.

Black grapes are effective in fighting a wide range of cancers. Rich in antioxidants, carotenoids and polyphenols, like the wonder compound resveratrol, studies have found that eating a diet rich in black grapes may reduce the risk of contracting certain cancers.

For instance, a study done by the University of Colorado Cancer Centre found that resveratrol is effective in preventing alcohol-related head and neck cancers. It prevents the creation of free radicals that cause cancer. Dont forget to eat the seeds and the skin that are very high in antioxidants. They are also rich in nutrients like Vitamins A, B-6, B-12, C and D, calcium, iron and magnesium.

Tip: Resveratrol in black grapes could increase longevity.

Does your brain tend to fog over every once in a while? Do you find your concentration wavering and mindfulness a task? Well, grab that bowl of juicy black grapes without any further delay. Studies have proven that eating a diet rich in black grapes helps improve brain function and protects it from age-related degeneration. This is also due to the benefits bestowed by antioxidants like resveratrol that control mood swings and delay memory loss due to ageing.

Some studies have shown that resveratrol may help stave off Alzheimers disease. The riboflavin in black grapes is also very useful for those who tend to suffer from headaches and migraines.

Tip: Black grapes contain melatonin that is known to aid sleep.

Type 2 diabetes is a huge health concern in India. According to recent government data, around 72.96 million adults have diabetes in India. To make matters worse, diabetes, often considered an urban affliction, has now spread its tentacles into the rural populations as well. In this scenario, it is heartening to note that eating black grapes regularly may help reduce the incidence of diabetes. This is because black grapes regulate insulin levels and up insulin sensitivity. Grapes also have a compound called Pterostilbene that helps to keep blood sugar levels in check.

Besides this, black grapes are low on the glycaemic index (GI figures indicate how much carbohydrate foods raise blood sugar levels). Do note, however, that black grapes should be eaten in moderation because of their high sugar content. Dont eat more than 10-15 grapes in one serving.

Tip: Black grapes help also relieve constipation and indigestion.

As we have mentioned earlier, black grapes help stave off metabolic syndrome mainly due to their potent antioxidant action. The metabolic syndrome causes a host of problems like low-grade inflammation which leads to Osteoporosis. A Danish study on men with metabolic syndrome found that a diet rich in resveratrol increases spine bone density. Taking a high dose of resveratrol (500g) led to a 2.6 per cent increase in lumbar spine volumetric bone mineral density.

Tip: Grapes can be stored in the fridge for about a week.

Black grapes are not just fantastic for your health; they are great for your skin and hair as well. And the wonder component in them is the potent black grape seed oil that has a host of beauty benefits. Grapeseed oil is an essential component of many beauty products. Black grape seed oilis rich in antioxidants and vitamin E that help your scalp remain healthy by increasing blood circulation, preventing hair fall, split ends and early greying. Grape oil also aids in promoting hair growth and bestows you with a healthy head of hair.

Black grapes are your skins best friend as they contain compounds like proanthocyanidins and resveratrol that shields you against harmful ultraviolet rays. If you are suffering from pigmentation, eat plenty of black grapes because they reduce the appearance of dark spots. The high vitamin C content in black grapes also keeps those wrinkles away, rejuvenates skin cells, and increases skin elasticity. A study by the University of California, Los Angeles, found that resveratrol has amazing acne-fighting properties when combined with the medication benzoyl peroxide.

Tip: When buying grapes make sure that they are firmly attached to the stem and are not wrinkled.

A. Choose grapes that are fleshy and firm. They should be firmly attached to the stem and not wrinkled or mouldy.

A. Some studies suggest that eating black grapes may help you sleep as they contain a compound called melatonin that is known to aid sleep.

A. Black grapes are a low GI foodand a cup of black grapes (about 100 g) contains 95 calories. However, they are rich in sugar, so dont overdose on them. Eat them with other fruits and limit servings to 10-15 grapes.

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Black Grape And Their Many Health And Beauty Benefits - Femina