Free Webinar – Clarient PATHSiTE Scope IA: Improving Patient Care – Powered by Definiens.

Clarient_Definiens_200px Please Join Definiens with special guest Dr. Roscoe Atkinson, M.D. from Clarient Inc. for a free webinar on May 11th, 2011 @ 11am EST:

Clarient PATHSiTE Scope IA: Improving Patient Care – Powered by Definiens.

Topics that will be covered:

- The evolution and development of Image Analysis and Scope IA at Clarient Inc.
- Clarient’s utilization of Definiens algorithms and technology
- How Clarient’s application of Scope IA and Definiens improves patient care

Speakers:

- Dr. Roscoe Atkinson, M.D. – Pathologist, Clarient
- Peter Duncan – Director, Marketing and Business Development Translational Research, Definiens

Title:    Clarient PATHSiTE Scope IA: Improving Patient Care – Powered by Definiens.
Date: Wednesday, May 11, 2011
Time: 11:00 AM – 12:00 PM EDT

Reserve your Webinar seat now at:
https://www2.gotomeeting.com/register/173191610

After registering you will receive a confirmation email containing information about joining the Webinar.

Mikroscan images to be seen

Despite mentioning MikroScan 3 times during the month of November, I inadvertently omitted mentioning them in my Year in Review post at the end of December.  While details began to come out about the size, capacity and price of the device, I did not know what scan times or image quality were and how they compared with established vendors or higher throughput devices. 

Last month someone attending the USCAP meeting sent me a text that read "They are 3 deep in the MikroScan booth".  The images I was told were of high quality with ease of use on the scanner and viewer side. 

I had to see for myself.  After accepting my offer to scan my slides complete with cracked cover slips, air bubbles, pen marks, fingerprints and coffee stains along with the tincture of time for some of the slides, the challenge was on. 

A few days later with remote viewing through join me, a simple and easy application,  I got what one would expect - a digital reproduction of every cell and the flaws on/in the slide.  Despite intentionally using non-ideal slides, the images were excellent and the artifacts, while present were no more a distraction or deterrant to viewing the slides than if I were at a microscope. 

What does this mean for the digital pathology user and laboratories?

For use cases that have a limited number of slides in an environment with limited space available (i.e. pathologist office, frozen section, cytology cart) this may just be what the doctor's doctor ordered for a rapid, reliable whole slide image that can be viewed for solo pathologist support, remote frozen section consultation between pathologists or immediate FNA interpretations.

This is not to suggest that it eliminates devices that process 4,5 or 300 or more slides with workflow and image managment software capabilities from the respective manufacturer.  I am suggesting users may need both. 

One device for the 1 or 2 slide frozen section or FNA case or limited consultation within arm's reach of a pathologist or technical assistant and a larger capacity device for large cases to be signed out, tumor boards, image analysis and archiving, likely to be centrally located where there is the greatest volume of slides and pathologists.

For more information check out http://www.mikroscan.com.

 

2011 ASCP Annual Meeting/WASPaLM XXVI World Congress – Abstract Deadline Near

  • Submissions cannot have been presented, published, or submitted for presentation or publication elsewhere.
  • All abstracts must be submitted electronically by April 29, 2011. Late abstracts, or those received by any means other than the ASCP abstract submission website will not be reviewed by ASCP.
  • Abstracts must be submitted in English. Submitting an abstract does NOT guarantee its acceptance at the 2011 ASCP Annual Meeting/WASPaLM XXVI World Congress. ASCP will provide notification of final status to all abstract submissions by July 1, 2011.
  • Particular attention should be given to products or equipment that bear registered trade names. Provide the company name and its city and state address parenthetically following the first mention of the product.
  • References should not be used. No charts, figures, or tables should be used.
  • Notice of acceptance will be sent via e-mail only. When setting up your user account, please use all fields for author and administrative support so that you will receive notices in a timely manner.
  • An initial confirmation e-mail will inform you of the receipt of your submission.
  • Authors will be notified in late summer of their status as a finalist in a poster competition, selection for an oral platform presentation, or poster session day and time assignment.
  • All submitted abstracts will be peer reviewed. Refer to the “Abstract Submission Guidelines” for grading criteria and other details of the abstract submission process.
  • For further information please e-mail us at abstracts@ascp.org or call 312-541-4943.

You may download a PDF copy of the abstract submission guidelines by clicking here.

Ronald Reagan UCLA Medical Center Uses Aperio’s Digital Pathology System to Provide Anatomic Pathology Consulting Services to China

30 UCLA Sub-Specialty Pathologists Available to Second Affiliated Hospital Zhejiang University

Vista, CA – April 26, 2011 - Aperio, the global leader in providing digital pathology solutions that improve patient care, today announced that its digital pathology system is being used to support subspecialty pathology consultations between Ronald Reagan UCLA Medical Center (UCLA) in Los Angeles, Calif., and Second Affiliated Hospital Zhejiang University, (ZHU) a 2,000-bed top-ranked hospital located in Hangzhou, China. 

UCLA has a pool of more than 30 sub-specialty experts in pathology that are available to provide remote medical consultation services to China for unusual and complex cases. Aperio’s patented scanning technology allows pathologists at ZHU to capture a digital slide image at very high resolution of the entire tissue sample on a glass slide and share it with pathology experts at UCLA in a secure web-based environment. More than 100 cases have been remotely reviewed to date. The Aperio digital pathology system facilitates the ability to bring high-quality, expert pathology services to China, significantly improving intra and inter observer agreement and ensuring effective treatment to improve patient care. 

“UCLA and ZHU selected the only true global leader in digital pathology that can deliver a complete remote consultation capability today,” said Dirk G. Soenksen, CEO of Aperio. “Aperio is helping healthcare organizations of all types deliver sub-specialty pathology services via online access to topnotch virtual pathologists. Pathology expertise is just a mouse click away anywhere in the world to help ensure the best pathology services possible in a fast and cost-effective way.” 

Use of Aperio’s patented ScanScope® scanners, Spectrum™ image management (PACS) software and remote viewing technology allows U.S. healthcare companies to compete at an international level, facilitating real-time, high performance access to high-resolution digital slide images. 

Jonathan Braun, M.D., Ph.D., chair of pathology and laboratory medicine, and professor of molecular and medical pharmacology at the David Geffen School of Medicine at UCLA, stated, “Digital pathology allows UCLA to offer the advanced skills of our sub-specialty pathologists to China in real time when a specific type of pathology expertise is needed quickly on a difficult or complex case. Our collaboration illustrates how integral pathology is to patient outcomes. Pathologists have become influential partners in treatment. Digital pathology dramatically enhances our ability to provide patient-centered care.” 

UCLA and ZHU pathologists also participate in frequent digital slide conferences using the Aperio system to review individual cases. Pathologists can view annotations on the digital slide image created by other reviewers, while simultaneously adding annotations for others to see. A common cursor superimposed on the digital slide is visible and can be manipulated by all conference participants. The hospitals are also conducting multi-disciplinary conferences, where experts across various disciplines (oncology, radiology, surgery) convene to discuss difficult cases. 

With more system installations than all other digital pathology vendors combined, Aperio is the true global leader and reliable choice for world class digital pathology solutions. The company boasts a global installed base of more than 800 systems in over 30 countries, including more than 500 systems in hospitals and reference laboratories, the 13 largest pharmaceutical companies and a multitude of biotechnology and government organizations.  

 

Exhibitors Sought for the Pathology Informatics 2011 Conference in Pittsburgh

We are seeking exhibitors for the Pathology Informatics 2011 conference that will take place at the Wyndham Hotel in Pittsburgh on October 4-7, 2011. This conference resulted from a merger of two previous pathology informatics conferences, Lab Infotech Summit and APIII. The inaugural merged conference was held in Boston last September. A total of 41 exhibitors participated in that event with about 250 paid registrants in attendance.

via labsoftnews.typepad.com

Regional Healthcare Event Series by Aperio — Atlanta, Philadelphia & Baltimore this May

Join us for the 2011
“Discover Your Path to Improved Patient Care”
Regional Healthcare Event Series

featuring Jared N. Schwartz, M.D., Ph.D., 
Aperio technical experts, and leading innovators who will
discuss how they are using digital pathology.


May 17 ~ Atlanta, GAHealthcare Regional Events
Seminar Event
 
May 18 ~ Philadelphia, PA
User Group*
 
May 19 ~ Baltimore, MD
Seminar Event


All events are complimentary and include validated parking, breakfast, and lunch.

Topics vary by location and include:

• Digital Pathology Beyond the Scan: Improving Patient Care and Enabling Personalized Medicine 

• Tips and Tricks for Spectrum Plus and ScanScopes

• Phased Adoption: Helping Hospitals Implement Digital Pathology

• Global Research Collaboration in a Shrinking World - Unlocking the Possibilities

• Virtual Microscopy Meets Next Generation Sequencing: Strange Bedfellows in the Genomic Age

• From Teaching to Research - Practical Use of Aperio in an Academic Institution

• Selected Topics in Image Analysis for IHC

• Special Local Area Speaker Sessions

• Roundtable Discussions


RSVP TODAY TO RESERVE YOUR SEAT!
To RSVP for any of these events, contact Nicole Siska, Aperio Events Team, at 760.539.1193 or nsiska@aperio.com

*The May 18 Philadelphia event is intended for Aperio users who have a working knowledge of the Aperio system. 

Philips and NEC Team Up in Digital Pathology

This sounds interesting -- combination of high-end imaging system from Philips with added quantitation tools provided by NEC.  According to the press release, look for results of this partnership by years' end.
 
Eindhoven, the Netherlands and Tokyo, Japan – Royal Philips Electronics (NYSE: PHG, AEX: PHI) and NEC Corporation (NEC; TSE: 6701) today announced the signing of an agreement under which the two companies will jointly develop and market highly integrated digital pathology solutions. Based around Philips’ new high-throughput pathology slide scanner and NEC’s e-Pathologist Cancer Diagnosis Assistance System, these innovative digital pathology solutions will be designed to use advanced digital techniques to add quantitative analysis to the qualitative information derived from the visual inspection of pathology slides, which is currently the standard procedure. They will initially be targeted to assist in the grading of breast cancer and prostate cancer.
 
Whenever a lesion is suspected to be cancerous or pre-cancerous, the normal procedure is to remove a sample of tissue from it (a biopsy) and send it to a pathology lab for examination by a pathologist. To conduct this examination, a thin section of the tissue is mounted on a glass slide, stained with chemicals to highlight various structures and visually examined under a microscope. With the increasing incidence of cancer and the growing need for methods of sub-typing the disease in order to deliver optimized therapy, there is a real need for digital pathology systems that speed up the workflow, while also providing pathologists with additional checks to improve diagnostic quality and specificity.
 
“Reliable computer-aided identification of regions of interest, based on the morphology of potentially cancerous cells in stained tissue samples, clearly depends on having high quality images to work with,” says Tadashi Higashino, Senior Vice President at NEC. “We firmly believe that the continuous auto-focus technology developed by Philips for use in its slide scanners will provide exceptional image detail and quality, allowing our advanced image analysis and machine learning algorithms to achieve optimum results.”
 
“With its e-Pathology system, NEC already has an impressive position in the digital pathology market in Japan and is well positioned to duplicate that success in many other parts of the world,” says Perry van Rijsingen, Senior Vice President and General Manager, Philips Healthcare Incubator. “I believe our joint development of highly integrated systems that combine superior slide scanning with state-of-the-art image analysis will be essential to unlocking the growth potential of digital pathology by helping to meet the ever-increasing demand for high-volume high-throughput pathology solutions.”
 
Philips’ ultra-fast slide scanner, which is already commercially available only in Europe for research purposes, employs a unique ‘continuous auto-focus’ technology that accurately follows height variations in the tissue surface over horizontal distances as short as 30 microns, allowing extremely high definition full-slide images to be captured in under one minute per slide.

NEC’s e-Pathologist system will use ‘machine intelligence’ to detect tissue and cell features within these images in order to identify regions of interest and make quantitative measurements of key structures in conventionally stained (Hematoxylin & Eosin) tissue samples, or samples stained with immunohistochemistry reagents. These quantitative measurements could assist pathologists in making decisions relating to the clinical treatment of cancer in individual patients. NEC has jointly evaluated this system with SRL, Inc., the largest laboratory test center in Japan, for biopsy of stomach cancer and has also started marketing a system focused on stomach and breast cancer. In addition, NEC has jointly evaluated its e-Pathologist system with the Massachusetts General Hospital (MGH) in the USA.

“As a leader in medical innovation, Massachusetts General Hospital Pathology has long been committed to utilizing imaging and data analysis for diagnosis and discovery. Digital pathology and diagnostic imaging analysis are obviously important areas of development driving such innovation,” said Dr. David Louis, Chief of Pathology at MGH. “

We are pleased to have been involved in the development of the Philips high throughput scanner and the NEC e-Pathologist system and look forward to the next phase of their development."

The digital pathology solution of Philips features an open architecture that allows partners/vendors to expand the system’s capability by integrating their own added-value hardware and/or software algorithms into it. This will allow the creation of total system solutions designed to empower pathologists by delivering increased workflow efficiency, improved diagnostic performance and better patient outcomes. Partnering with Philips, a world leading company in healthcare markets, will therefore help NEC to develop its technology to suit worldwide market requirements.
 

Philips and NEC aim to produce initial development results from their joint development in digital pathology within the current year.

Dr. David Eberhard joins Flagship Biosciences as Chief Medical Pathologist

Pharmaceutical veteran anatomic pathologist strengthens Flagship's expertise in oncology and clinical trials

Flagstaff, AZ (04/26/2011) —Flagship Biosciences announced today that Dr. David Eberhard MD, PhD has been appointed Chief Medical Pathologist. Dr. Eberhard is an anatomic/molecular pathologist highly regarded for his leadership and expertise in oncology clinical trials and pharmaceutical drug development. He holds an academic appointment as Associate Professor, Department of Pathology and the Lineberger Comprehensive Cancer Center, at the University of North Carolina at Chapel Hill. Previously, he served as the Director of Clinical Trials Pathology Services at LabCorp’s Center for Molecular Biology and Pathology, after a distinguished career at Genentech and as an industry consultant. He earned his MD in Pathology and his Ph.D. in pharmacology from the University of Michigan Medical School, followed by residency training in anatomic pathology and neuropathology at the University of Virginia School of Medicine.

Dr. Eberhard has been active in developing standardized approaches for molecular pathologic analyses of solid tumors in clinical trials, such as the publication of industry working group recommendations for EGFR testing in pathology. “The addition of Dr. Eberhard to Flagship’s pathology and development team further strengthens our position as a leader in qualitative and quantitative digital pathology.” said Dr. David Young, President of Flagship Biosciences.“He has been a steady encouragement from the beginnings of Flagship and has a great vision for applications of image analysis in both research and clinical medicine”. 

David Eberhard has served on the Scientific Advisory Board for Flagship Biosciences, and in his new expanded role will strengthen the collaboration provided by Flagship’s network of anatomic pathologists of various specializations in the United States and Europe, and facilitate closer interactions and innovation between Flagship’s new quantitative pathology approaches, academic investigation and oncology drug development. 

“Flagship has a unique focus on cutting-edge digital pathology approaches to maximize efficiency of anatomic pathology analyses, to allow precise, accurate and reproducible quantitation of pathology readouts, and to support the clinical development of drugs and companion diagnostics” said Dr. Eberhard. "Flagship's perspective and expertise represent a valuable resource for basic, translational and clinical R&D that has huge potential to create real progress in science and industry."

Flagship Biosciences is a pathologist-owned pharmaceutical services organization that specializes in the delivery of quantitative pathology to pharmaceutical, biotech, and medical device clients. Flagship leverages digital pathology to combine novel quantitative scoring algorithms with anatomic pathology expertise and experience. They are the largest provider of pathologist-supervised brightfield and fluorescence scanning and custom image analysis capabilities.

 

Proposed Accountable Care Organization Regulations

On April 7, 2011, the Centers for Medicare & Medicaid Services ("CMS") issued its proposed regulations covering Accountable Care Organizations ("ACOs"). When adopted in final form, this rule will implement Section 3022 of the Patient Protection and Affordable Care Act, which requires CMS to establish a Shared Savings Program by January 1, 2012. These proposed regulations are the first in a series, and set forth the basic eligibility requirements for ACOs to participate in the Shared Savings Program; quality of care and other reporting measures; the methodology for assigning Medicare beneficiaries to ACOs; the payment methodologies under the Shared Savings Program; monitoring of ACOs for compliance with applicable criteria; and the sanctions for non-compliance. Comments regarding the proposed regulations are due by June 6, 2011. This alert is intended to provide only a high level summary of the proposed regulations.

The proposed regulations define an ACO as a legal entity recognized to conduct business under state law, with a governance structure that will enable it to receive and distribute shared savings, establish and report compliance with the ACO quality and reporting requirements, and perform other tasks set forth in the regulations. An ACO may be established by: (a) professionals in group practices, (b) networks of individual practices, (c) ventures between hospitals and professionals, (d) hospitals who employ professionals, and (d) critical access hospitals. Other health care providers and suppliers may participate in an ACO, but they cannot establish an ACO. It is important to note that primary care professionals (which include professionals in the specialties of general practice, family practice, internal medicine or geriatric medicine) can only be ACO participants in a single ACO, whereas other types of providers, such as specialist physicians, may participate in multiple ACOs.    

Click here for full text of the alert.

Courtesy of McDonald Hopkins

Aperio Awarded Patent for Innovation that Improves Digital Pathology Workflow

Aperio continues to add to its IP portfolio with streamlined workflow patented technology.

Creation of complete digital slide image file - during scanning - results in fastest scanners, streamlines workflow and simplifies IT

VISTA, Calif.--(BUSINESS WIRE)--Aperio, the global leader in providing digital pathology solutions that improve patient care, announced today that the United States Patent and Trademark Office has issued the company patent No. 7,826,649 entitled, “Data Management in a Linear-array-based Microscope Slide Scanner.”

The ‘649 patent describes techniques invented by Aperio for efficiently processing large image files — during the scanning process — to create a single high-quality digital slide image. The ability to create a single digital slide, including image compression, during the scanning process results in faster overall scanning and streamlines digital pathology workflow.

“This patent highlights our ability to create a single digital slide image during the scanning process, which is why our scanners continue to be the fastest on the market,” commented Dirk G. Soenksen, CEO of Aperio. “Our sub-95 second scan time includes all steps required to create a single digital slide image file by the scanning instrument. This patent requires others to divide the scanning process between the scanning instrument and a dedicated server, and to post-compress the imagery data on the server. Doing so takes much longer than their advertised scanning time, complicates the workflow, and requires moving and storing gigabytes of imagery data.”

Aperio has the highest throughput scanners available today. The company’s family of ScanScope® scanners are based on line-scanning, which has become the standard for scanning performance and image quality in the digital pathology industry. Line scanning rapidly produces seamless digital slide images with unsurpassed image quality, and is critical to a pathologist’s ability to make informed diagnoses and prognoses of diseases.

The patent strengthens Aperio’s comprehensive intellectual property portfolio comprising more than 80 issued and pending patents world-wide, and provides the company with ownership of key innovations that address critical pathology imaging needs.

With more system installations than all other digital pathology vendors combined, Aperio is the true global leader and reliable choice for world class digital pathology solutions. The company boasts a global installed base of more than 800 systems in over 30 countries, including more than 500 systems in hospitals and reference laboratories, the 13 largest pharmaceutical companies and a multitude of biotechnology and government organizations.

About Aperio

Aperio is the leading provider of digital pathology solutions in hospitals, reference labs, and pharmaceutical and research institutions across the world. Today, our affordable and complete product portfolio improves patient care by enhancing quality assurance, delivering more efficient workflows, facilitating access to new and more targeted therapies, and improving pathologists’ skills via lifelong education. Our comprehensive product line features our ScanScope® scanners, Spectrum™ image management (PACS) software, SecondSlide® slide sharing service for pathology, and image analysis tools and services. Aperio’s products are FDA cleared for specific clinical applications, and are intended for research and education use for other applications. For clearance updates and more information please visit http://www.aperio.com.

 

VA awards $1.38 billion in telehealth contracts

Courtesy of FierceMobileHealthcare:

The Department of Veterans Affairs this week awarded contracts to six IT vendors to run its massive (and growing) telehealth program for the next five years. The winners: Authentidate, American Telecare, Cardiocom, HealthHero Network, Visual Telecommunication Network/ViTelCare, and Viterion TeleHealthcare.

The prize: About $1.38 billion in VA telehealth contracts. The individual vendor contracts run anywhere from $150 million to $372 million over the five-year period, VA officials tellFierceMobileHealthcare. That total isn't guaranteed, though. Each vendor starts out with a single-year contract, which is renewable in each of the following four years.

What's really interesting: The VA's clear leap into telehealth. The smallest of the new contracts--$150 million for Viterion Tele-Healthcare--is just shy of the agency's entire telehealth budget of$163 million last year. It is somewhat on trend, though, given that the 2010 budget was a 50 percent jump over 2009 spending.

The contracts do cover both traditional video-based telehealth systems, according to Authentidate officials. They also cover sensor-based remote monitoring systems in patient homes.

To learn more:
- read Authentidate's press release
- check out MobileHealthWatch's coverage

Related Articles:
VA's telehealth budget may double, but strategic questions linger
Veterans using mobile devices for follow-up care
Telehealth prevents ICU deaths, VA research shows

 

The Essential Guide to Achieving the Perfect Pathology Fellowship: Useful Advice and “Must-Do’s” for First-, Second- and Third-Year Residents

How to build teamwork, boost productivity, and enhance harmony
in your lab’s multi-generational workforce

Jared Gardner, MDRobert Petras,  MD

YOUR PRESENTERS:

Jerad M Gardner, M.D., Chair, CAP Resident Forum and Fellow, Soft Tissue

Robert E. Petras, M.D., FCAP, FACG, Managing Director, Ameripath, Inc.

Justin M. Clark (Moderator), Director of Operations, THE DARK REPORT



LIVE Webinar April 28 – Register Now!

Early in their four-year residency programs, pathology residents should start searching for the perfect fellowship, and employers should emphasize the need for residents to acquire subspecialty expertise before they begin a career in pathology and laboratory medicine.

On Thursday, April 28, 2011, the Pathology Residents Education Program (PREP) has a timely learning opportunity designed to help pathology residents identify, apply, and interview for the perfect pathology fellowship. During this 50-minute webinar, you’ll learn precisely what it takes to demonstrate your skills and competencies—and then nail down an offer for the ideal pathology fellowship.

Our first speaker, Robert Petras, M.D., is internationally known for his subspecialist expertise in gastrointestinal pathology. Dr. Petras accepts fellows and will give you an insider’s perspective on all aspects of the fellowship experience. He has been active in promoting fellowship programs at the national level and has invaluable insights into how you can stand out as an applicant.

You’ll also hear from Jerad M. Gardner, M.D., Chair of the CAP Resident Forum and Fellow, Soft Tissue Pathology at Emory University. From the pathology resident’s perspective, Dr. Gardner offers practical information about the do’s and don’ts of submitting fellowship applications, handling the interview process, and responding appropriately to post-interview communications.

This webinar is perfect for first-, second- and third-year pathology residents who want to identify and obtain the ideal pathology fellowship. Pathology residency program directors and chairs of pathology will also find this information invaluable, and will want to make it available to their residents.

Pathology fellowships aren’t easy to get. To get a fellowship offer from your first choice, it’s essential for you to understand how to distinguish yourself from the other applicants. Find out what it takes to get a fellowship in either an academic or non-academic setting, including how to select a subspecialty, how to become a competitive candidate, and how to navigate the fellowship application process.

You’ll also learn about the fellowship interview and selection criteria and what you can do to prove you’re the best candidate for the position. We’ll even prepare you for handling an offer of acceptance—and what to do if you’re turned down.

If you’re a resident looking for a fellowship opportunity, this session will give you a head start by taking you through the application process and clearing up some of the more confusing aspects before you begin. Drs. Petras and Gardner offer insights, advice, and recommendations for conducting a search to find the best pathology fellowship in a non-academic setting.

Ask your chief resident or residency program director to register your residency program for this information-packed 50-minute webinar, The Essential Guide to Achieving the Perfect Pathology Fellowship: Useful Advice and “Must Do’s” for First-, Second- and Third-Year Residents,” on Thursday, April 28, 2011.

And don’t forget the question-and-answer session at the end of this conference. It’s your opportunity to get answers to specific questions about how to apply for a academic or non-academic pathology fellowship.


THE DARK REPORT WEBINAR AT A GLANCE

PLACE: Your computer or your residency program’s conference room

COST: $249 per download *Add 30 days of post-conference online access to the recording of this event for $75

TO REGISTER: Click here or call Suzanne Galloway toll-free at 1-800-560-6363


For one low price—just $249you and your entire team can take part in this fast-paced, insightful webinar. Best of all, you’ll be able to hear answers to your questions with the panelists when you here the Q and A session answers.

 Here’s just some of what you’ll learn during this in-depth 50-minute webinar:

  • How to select the right subspecialty.
  • Where to find out about the best pathology fellowship programs.
  • Easy steps for establishing yourself as the top applicant.
  • The best time to apply for pathology fellowships.
  • Why each fellowship program has different selection criteria.
  • Interviewing do’s and don’ts.
  • Advantages and disadvantages of the academic and non-academic experience.
  • Strategies for navigating the oft-confusing fellowship application process.
  • Must-do steps to take once you’ve been accepted into a fellowship program.
  • Why you need a backup plan—and what to do if you’re not accepted.

…and much more!

Individuals who benefit from this webinar download:

  • Pathology chief residents, residents and fellows
  • Academic pathology chairs
  • Residency program directors
  • Pathology department administrators
  • Undergraduate and graduate medical educators
  • Pathology and laboratory professionals

How to Register:

1. Online
2. Call toll free: 800-560-6363

Your registration order includes:

  • A site license to attend the webinar (invite as many people as you can fit around your computer at no extra charge)
  • A downloadable PowerPoint presentations from our speaker
  • A full transcript emailed to you soon after the conference

Register Now! Or for more information, call us toll-free at 800-560-6363.

Distinguished Experts:

Jerad M. Gardner, M.D. is Chair of the CAP Residents Forum and has served on the Residents Forum Executive Committee for the past three years. He is the soft tissue pathology fellow studying under Sharon Weiss at Emory University. This will be followed by a dermatopathology fellowship, also at Emory, beginning later this year. Dr. Gardner received his M.D. from Tulane University School of Medicine in 2006. He completed his residency in anatomic and clinical pathology at The Methodist Hospital. During residency, Dr. Gardner founded the Pathology Resident Wiki, a website that can be freely edited by any user. The main intent of the Wiki is to provide a comprehensive list of pathology fellowship and residency programs, including feedback about those programs from current and past trainees. He is passionate about helping residents understand and navigate the seemingly treacherous waters of the fellowship selection and application process.

Robert E. Petras, M.D. has been the National Director for Gastrointestinal Pathology Services at AmeriPath Inc. since 2002. He is also Managing Director of AmeriPath Cleveland, Medical Director and GI Pathology Fellowship Training Program, Director at AmeriPath’s Institute of Gastrointestinal Pathology and Digestive Disease Chairman of AmeriPath’s Gastrointestinal Pathology Resource Committee and an Associate Clinical Professor of Pathology at Northeastern Ohio Universities College of Medicine. Prior to 2002, Dr. Petras chaired the Department of Anatomic Pathology, was Vice Chairman of the Division of Pathology and Laboratory Medicine, and directed the Pathology Residency Training Program at the Cleveland Clinic Foundation. He received his doctorate of medicine from The Ohio State University College of Medicine and completed his residency at the Cleveland Clinic. Afterwards, he received subspecialty training in gastrointestinal pathology at St. Mark’s Hospital in London. He has been active in the American Society for Clinical Pathology (ASCP), the College of American Pathologists (CAP), and the United States and Canadian Academy of Pathology (USCAP). He frequently presents as faculty at various courses and workshops. He has received numerous awards including the 1997 ASCP Distinguished Service Award and the 2001 Impact Paper of the Year Award from the American Society of Colon and Rectal Surgeons. He has co-authored more than 200 publications in gastrointestinal pathology including Tumors of the Intestines, part of the AFIP Atlas of Tumor Pathology Fascicle series.

The Daily Scan on iPhone

The Daily Scan - Aperio's daily news and views about Digital Pathology and many other services has an iPhone App that keeps you connected to the site.  Click on image below for larger size.  App free of charge from iTunes store.

2011-04-18_22-03-13

iPhone 5 Rumor Mill

When Apple announced that it would be holding its annual Worldwide Developers Conference in June, the rumor mill started to heat up. From every corner of the world, so-called sources were saying what Apple will and won’t announce at the show. Many of those rumors surrounded the iPhone 5. Historically, Apple has announced details about the new iPhone at a keynote address to kick off the event. However, some say it won’t do that this year. Other reports, of course, say it will. In either case, it’s clear that there are many question marks surrounding the iPhone 5 that Apple is unwilling to answer. But that doesn’t mean that those questions should be ignored. Apple’s iPhone is integral to its success. And it relies upon consumer excitement to help maintain its increasing revenue and profits. Simply put, the iPhone 4 and the upcoming iPhone 5 are integral to Apple’s operation. And the sooner it answers the many questions consumers have, the better it will be for the company. Read more.

Recent MLO Articles on Digital Pathology

When I received my copy of MLO Medical Laboratory Observer this past week it reminded me there were a few articles of interest last month in the journal.  Both provide value propositions for digital pathology with use cases illustrated by Dr. Schwartz of Aperio.

Digital Pathology and imaging — past, present, and future

By Karen Lynn 

The first focus of digital pathology was to automate the microscope. “The ultimate goal was to begin the migration from a physical slide to a digital image and ensure users’ comfort during the transition,” says Jason Christiansen, PhD, senior director of Operations at HistoRx. In its earlier days, image-analysis applications were produced but limited to existing testing paradigms which had less impact than the leap to slide digitization. Fast-forward five years. Today, image quality is virtually identical to viewing a glass slide under the microscope. In fact, pathologists are willing to make diagnoses based on an image versus actual glass.

Viewing slides digitally gives numerous advantages that glass slides do not provide; for example, tumors and areas suspicious for disease can be measured more precisely; images can be manipulated and utilized for consultation and teaching purposes; images can be viewed by more than 100 people simultaneously from anywhere in the world; and automated, quantifying algorithms for estrogen receptors, progesterone receptors, and HER2 have since been developed and FDA-cleared, reports Joon Yim, MD, director of digital pathology at Acupath Laboratories. In addition, digital pathology supports rapid-assessment turnaround time for frozen sections which are critical to surgical protocols, and those slides can be digitally imaged and stored in a central repository.

Full text
Expanding the lab’s reach with digital pathology

By Jared Schwartz, MD, PhD 

Advances in digital-pathology systems, including rapid slide creation, data management, and image-visualization techniques are transforming the practice of pathology. A powerful tool in anatomic pathology, advancements in digital pathology continue to enhance efficiency and accuracy, resulting in lower costs, significant workflow efficiencies, and improved patient care.

Digital slides are a complete representation of the entire glass slide, viewable on a computer monitor at any magnification. Web-based pathology picture archiving and communication system, familiarly known as PACS, allow pathologists to work remotely anytime, anywhere, to deliver accurate results faster than traditional methods.

As digital pathology becomes more accessible for the average lab, the ability to work digitally provides opportunities to offer new services and tests, attract new customers, and create new business lines. Implementing an outreach business enabled by digital pathology is an emerging strategy that is helping many labs maintain market share and increase growth and profitability.

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Molecular Pathology Laboratory Network, Inc. Selects mScope Clinical For Its Pathology Imaging Communications & Integration Platform


This new partnership signifies a major breakthrough with a market 
leader in Comprehensive, Personalized Testing Services

MONTREAL (CANADA), April 13, 2011 – Aurora Interactive Ltd., a world leader in digital pathology communications announced today that the company has signed a license agreement for its mScope Clinical communications and imaging modalities integration platform with Molecular Pathology Laboratory Network, Inc. (MPLN), a leader in specialized reference laboratory services dedicated to providing superior diagnostic testing and complementary technologies, including molecular diagnostics, flow cytometry, fluorescence in situ hybridization,immunohistochemistry and cytogenetics.

“We chose Aurora for their cost efficient plug-and-play and proven integration solution. Given the variety of imaging modalities we use, we considered Aurora’s universality key to maintaining our strategic flexibility and creating a common user interface for our internal and external clients,” said Steve Olsen, MS, HTL (ASCP), Chief Operating Officer of MPLN.

“We are very excited about MPLN’s decision to partner with Aurora. MPLN is a cutting edge provider who is dedicated to client service and making a difference in patient care. We are proud they chose us as their communications and integration partner” stated Pierre Le Fèvre, President and Chief Executive Officer, Aurora Interactive.

About Aurora Interactive Ltd.

Aurora Interactive has developed the leading web based software platform (mScope) for simplification, productivity and ease of communications in digital pathology. mScope’s Universal Web Viewer has collaborative tools to view medical slides and images anytime, anywhere, regardless of file format. The software has four applications to meet digital pathology communications needs: mScope Education, mScope Clinical, mScope Research and mScope Universal Viewer. Aurora’s mission is to improve patient outcomes and help members of the medical community achieve their full potential by eliminating the learning, diagnostic and collaborative restrictions imposed by time and space. http://www.aurorainteractive.com.

About Molecular Pathology Laboratory Network, Inc.

Molecular Pathology Laboratory Network, Inc. (MPLN) is a privately-owned regional reference laboratory founded in 1989 with headquarters in Maryville, Tenn. and a satellite laboratory in Richmond, Va. A leader in personalized laboratory medicine, MPLN specializes in oncology and women’s health testing and has extensive expertise in chromosome analysis, flow cytometry, fluorescence in situ hybridization (FISH), real-time and quantitative polymerase chain reaction technologies, anatomic pathology, immunohistochemistry and gene sequencing. The laboratory also offers research and development services through its clinical trial division, Geneuity Clinical Research Services. MPLN is certified by the Clinical Laboratory Improvement Amendments (CLIA), accredited by the College of American Pathologists (CAP), and licensed by the states of Tennessee, Florida, New York and Maryland. For more information about MPLN, visit http://www.mplnet.com.


University of Minnesota licenses multiplexing software to Flagship Biosciences

Flagship receives exclusive license to software that pairs quantitative techniques with pathology expertise

MINNEAPOLIS / ST. PAUL (04/14/2011) —The University of Minnesota has finalized a license agreement with Flagship Biosciences for software that provides quantitative analyses of protein expression levels in human tissue samples. The software, IHC Map, improves a pathologist’s ability to characterize diseased tissues and assists researchers with clinical trials for pharmaceuticals and medical devices.

The exclusive license agreement for the university-developed software has also forged a partnership between BioNet, a central tissue procurement and research histology lab on the university’s Twin Cities campus, and Flagship Biosciences, a private company based in Flagstaff, Ariz. Flagship performs histopathology services for biotech, pharmaceutical, medical device and cosmetic companies. Flagship offers IHC Map to its customers and also refers organizations to BioNet for additional tissue procurement and research services that it does not offer.

“Flagship provides digital pathology services, primarily to the pharmaceutical industry,” said Dr. Steve Schmechel, director of BioNet, assistant professor of laboratory medicine and pathology and co-inventor of IHC Map. “For many of those functions, companies require both academic surgical pathologist skills and access to biospecimens or techniques that they may not have internally.”

BioNet's tissue procurement and histology services are available to researchers in both the public and private sector.  The lab procures biospecimens, such as tissue and blood samples, from subjects who have given consent, stores the specimens and associated annotation data, and reports the data, from which patient-identifying information has been removed, to the researcher. 

The instrumental tool in this partnership between industry and academia is IHC Map, software that analyzes tissue samples and identifies protein markers for disease. Without the software, a pathologist must analyze multiple slides individually, and make a qualitative judgment on the results. IHC Map allows protein or gene signatures taken on multiple sections to be aligned and visualized in a heatmap-like fashion. The technology improves the multiplexing of biomarkers on a tissue section, and allows the computation of expression to be reported as a comparison to other more stable proteins in the sample. The patent-pending software was developed at University of Minnesota and will be refined in Flagship’s pharma services by both veterinary and medical anatomic pathologists.Flagship Biosciences helps pharmaceutical and medical device clients develop tissue-based diagnostics. “Seventy to ninety million glass slides are analyzed each year in pharmaceutical drug development, and maybe another ten million in medical device development,” said Steven Potts, CEO of Flagship.  “We think this collaboration will make it easier for these clients to have specialized medical pathology expertise combined with quantitative techniques from Flagship.”

“Most diseases are due to alterations of genes that manifest themselves at the level of protein expression,” said Schmechel. “To characterize disease it is very useful to look at protein expression. Often looking at the expression of one protein is not sufficient, or not powerful enough to optimally characterize the disease. It’s better to look at multiple proteins simultaneously.”

Identifying protein expression across multiple genes can answer key questions for researchers: What is the nature of the disease? How is it likely to behave in the patient? Will the disease be responsive to a given therapy? “It’s been found that combining information from multiple genes to characterize tissue is a powerful way to identify aggressive cancers,” said Dr. Greg Metzger, co-inventor of IHC Map and associate professor of radiology at the U of M. In addition to quantifying expression of these proteins in a quantifiable measurement, the software also allows for greater standardization across tissue samples, and requires less time for the pathologist to analyze slides.

IHC Map was invented by Schmechel and Metzger; Stephen Dankbar, a software programmer from the department of radiology; and Jonathan Henriksen, an information technology specialist from BioNet. The research was funded by the National Institutes of Health and the American Recovery and Reinvestment Act.

The mission of the University of Minnesota’s Office for Technology Commercialization is to translate University research into new products and services that provide growth opportunities for its licensees, benefit the public good, improve the quality of life, and generate revenue to support the University’s research and education goals.

 

George W. Moore, prominent pathologist, dead at 65

Dr. Moore was one of the smartest informaticians I have had the pleasure of knowing.  I first met him at an APIII meeting in 2001 where he embraced "E-posters" and made sure to look at yours.  His website, http://www.netautopsy.org lists over 400 publications, book chapters and abstracts and he was a mentor to many.  His interests in surgical pathology and autopsy pathology were broad and given his combined interest and expertise in medical and pathology informatics, allowed Dr. Moore to refine data mining techniques and create mathematical models of disease and disease processes.   

April 10, 2011|By Nick Madigan, The Baltimore Sun

A pioneer in medical informatics, he held appointments at Johns Hopkins Hospital and other institutions

Dr. George William Moore, who had practiced pathology in Baltimore since 1976 and was a pioneer in the field of medical informatics, died April 4 after a long illness. He was 65.

During his career, Dr. Moore published hundreds of articles on pathology and computational medicine. His work in the closely related fields of medical informatics and pathology informatics, both of which emerged in the 1970s, was groundbreaking. Medical informatics covers the broad field of hospital computerization, while pathology informatics deals with the organization, retrieval and analysis of clinical laboratory data collected in medical centers.

60797418 Dr. Moore, celebrated for a fine singing voice as well as a prodigious beard, held appointments at Johns Hopkins Hospital, the University of Maryland School of Medicine and the Baltimore Veterans Affairs Medical Center. He developed a wide range of computational techniques for collecting and indexing the data contained in pathology reports. He also established novel statistical methods for analyzing the collected data.

He was born in Detroit and grew up in the suburb of Highland Park. He was educated in public schools and graduated at the top of his class at Highland Park High School in 1963.

He attended the University of Michigan at Ann Arbor, where he majored in cellular biology and earned a bachelor's degree in science. He received his doctorate in biomathematics from North Carolina State University at Raleigh. After a year of postdoctoral training at the University of Freiburg in Germany, Dr. Moore returned to Detroit, where he earned a medical degree from Wayne State University School of Medicine in 1976.

Five years earlier, he had married the former Barbara Lynne Struble. They had two sons, Geoffrey Walter Moore, who was born in 1974 and died three months ago, and Gregory Vincent Wayne Moore, born in 1980, who survives him.

Dr. Moore and his family moved to Baltimore in 1976, and lived most recently in Cedarcroft. In 1981, he completed an internship and residency in the pathology department at Hopkins, and stayed on as an assistant professor in pathology until 1989. That year, he accepted an appointment as associate professor at the University of Maryland School Of Medicine and continued to teach at Hopkins' various institutions. Also in 1989, Dr. Moore began practicing as a full-time pathologist at the VA Medical Center, a position he held until his death.

In 1967, Dr. Moore was named a Woodrow Wilson Fellow, and in 1980 received the Ludwig Aschoff Medal from the Medical Society of Freiburg. In 2007, he was named an honorary fellow by the Association for Pathology Informatics.

From 1957 until shortly before he died, Dr. Moore sang tenor in various chorus societies. He was particularly proud to have been a chorus member in a performance by the Detroit Symphony Orchestra in 1959, under the baton of Paul Paray, as well as a performance in 1966 of the University of Michigan Choral Union conducted by the Russian-born composer Igor Stravinsky. Most recently, Dr. Moore sang in the choir for the Episcopal Church of Christ the King, in Woodlawn, where he was a member of the congregation.

In addition to his wife and son, Dr. Moore is survived by a brother, James Michael Moore, and a sister, Kathleen Elizabeth Moore.