How can nanomedicine be applied to cannabis? – Leafly

Imagine a world in which a tiny nanorobot could deliver a specific cannabinoid directly to your endocannabinoid (ECS) receptors. The nanorobot would be thousands of times smaller than the breadth of a human hair and could carry its small cargo inside a single droplet of liquid to deliver it directly to a target cell such as a cancer cell.

Sound far-fetched? It may be closer than you think, because researchers are making great strides in the fascinating field of nanomedicine.

The cannabis plant contains an amazing group of cannabinoids, terpenes, and flavonoids, and scientists are only beginning to unlock the complex pharmacology and potential of these compounds. Combined with nanomedicine, cannabis has even more potential to treat disease and provide overall health benefits for people.

Scientists can manipulate substances on an atomic scale, in the range of 1-100 nanometers, or one thousand times thinner than a sheet of paper. According to the US Nanotechnology Initiative, substances on the nanoscale have very different properties than bulk substances dounique properties like better electrical conductance, higher strength, and different magnetic properties, light reflection, or chemical reactivity. Nanotechnology can be performed on solids, liquids, or gases to unlock these unique phenomena.

For these reason, nanotechnology applications in medicine offer exciting promise and possibilities, especially when applied to cannabis compounds. Many nanotechnology applications are already in usecomputer circuits made from carbon nanotubes allow for far greater computing power, and nanoparticles are already being used in pharmaceuticals to improve absorption.

Researchers work on all kinds of aspects of nanotechnology, such as finding the best substance for nanoparticles, the best shape for a nanoparticle for a specific delivery, and the best transfer mechanisms for specific drugs. Nanoparticles can generate heat, deliver stem cells, be radioactive or metallic, and so much more.

While many applications are still only imagined by scientists, at its full potential, nanotechnology could be the next medical revolution, vastly changing how diseases are detected and treated.

One of the best applications of nanomedicine is in the area of drug delivery, whereby nanoparticles deliver substances directly to specific cells, like diseased cancer cells. Researchers can engineer nanoparticles to be attracted to a diseased cell and limit the ability to bind with and therefore damage healthy cells.

Scientists at MIT and other institutions have successfully used specific nanoparticles to deliver drugs to tumors. Even more interesting is that nanoparticles are developed to work togetherwhile one locates a tumor, another can use the signal from the first to effectively carry the drug to its intended target.

In one interesting application, scientists have created a nanoparticle that looks for hydrogen peroxide present in inflamed tissue, then it releases a drug in that environment to target heart disease.

There is great promise that nanotechnology and cannabinoids can make an impact on diseases like cancer, multiple sclerosis, Parkinsons, diabetes, and a wide range of serious inflammatory diseases.

Nanotechnology can help identify a disease at an early stage, perhaps even when a single cell has gone awry, and then deliver a targeted cannabinoid to correct a cells behavior, thus stopping the disease in its tracks. It may even be possible for a nanorobot to target a specific endocannabinoid receptor to shut down the entire inflammatory process for the betterment of a patient.

Cannabinoid nanodelivery systems have entered the research mainstream, with scientists working on biologically engineered cannabinoids and other nanoparticles to be transported to cells, and by creating nanocarrier transport substances out of metallics or other substances.

Delivery system research also touches on improving bioavailabilitythe rate at which the active substance of a drug enters the bloodstreamas well as improving the physical stability of nanoparticles and optimizing routes of administration, including injection, pills, or sublingual drops.

A nanotechnology-based targeted drug delivery system can be formulated to deliver cannabinoids directly to endocannabinoid receptors, where the magic happens. Cannabinoids can be packed inside a nanoparticle and carried to its intended target without degradation and with a controlled release.

For example, nanoemulsions are already used in the food industry to deliver probiotics or other bioactive ingredients in a very controlled release. These nanoemulsions use a combination of two liquids that dont normally combinesuch as oil and waterto serve as a barrier to chemical degradation for the cannabinoid while on its journey through the body.

Other encapsulation methods can help with potency issues by increasing absorption, they can help decrease side effects, and they can help cover a substances bitter taste.

Specific cannabis strains could even have tailored therapeutic profiles, and cannabinoids could be bioengineered to produce enhanced effects.

Scientists envision a superclass of cannabinoid nanocarriers that have potential to treat a wide array of endocannabinoid insufficiency issues and thus a wide variety of diseases.

In one example, researchers are looking at novel ways to deliver substances across the difficult blood-brain barrier. This barrier is the bodys built-in defense mechanism to protect the brain, so the ability to transport substances across it directly affects a treatments efficacy.

To this end, scientists are engineering lipid nanocapsules decorated with minute cannabinoids like CBD as novel therapies for diseases of the central nervous system.

Nanotechnology has already transformed drug delivery in profound ways, and cannabinoid delivery is part of this exciting future. There are challenges, of course. Cannabinoids quickly degrade in water and are susceptible to other kinds of degradation, and that presents delivery issues.

More recent discoveries, including the decoding of the cannabis genome, discovery of the main CB1R and CB2R receptors within the human endocannabinoid system (ECS), and discovery of other receptors, are also foundational efforts that contribute to cannabinoid nanotechnology.

The latest research shows great progress in the formulation of targeted cannabinoid-nanocarrier delivery systems, and as such may provide key therapies particularly for central nervous system disorders. As scientists continue to make improvements in both bio-efficacy and bioavailability, cannabis nanotechnology represents an exciting and brave new world.

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How can nanomedicine be applied to cannabis? - Leafly

(IMPACT OF COVID-19) Nanomedicine Market Research 2020 Next Big Thing | GE Healthcare, Johnson& Johnson, Mallinckrodt plc, Merck& Co. Inc.,…

Global Nanomedicine Market 2020-2027

GlobalNanomedicine Market Global Drivers, Restraints, Opportunities, Trends, and Forecasts up to 2027. Market Over viewing the present digitized world, 80% of the data generated is unstructured. Organizations are usingNanomedicine technology to unravel the meaning of such data to leverage business strategies and opportunities. A myriad of unstructured data is available online in the form of audio content, visual content and social footprints.

The segmental analysis focuses on revenue and forecast by Type and by Application in terms of revenue and forecast for the period 2020-2027.The Report scope furnishes with vital statistics about the current market status and manufacturers. It analyzes the in-depth business by considering different aspects, direction for companies, and strategy in the industry.

Our new sample is updated which correspond in new report showing impact of COVID-19 on Industry

The Key Players Profiled In the Market Include

Company Coverage (Company Profile, Sales Revenue, Price, Gross Margin, Main Products etc.)

The Key Players | * GE Healthcare, * Johnson& Johnson, * Mallinckrodt plc, * Merck& Co. Inc., * Nanosphere Inc., and * Pfizer Inc.

For Better Understanding, Download Sample PDF Copy of Nanomedicine Market Research Report @

After analyzing the report and all the aspects of the new investment projects, it is assessed the overall research and closure offered. The analysis of each segment in-detailed with various point views; that include the availability of data, facts, and figures, past performance, trends, and way of approaching in the market.The progressive growth in Nanomedicine Market report also covers the in-depth analysis of the market dynamics, price, and forecast parameters which also include the demand, profit margin, supply and cost for the industry.

Key question and answered in the report include:

What will the market size and the growth rate be in 2027?

What are the key factors driving the GlobalNanomedicine Market?

What are the key market trends impacting the growth of the GlobalNanomedicine Market?

What are the challenges to market growth?

Who are the key North vendors in the GlobalNanomedicine Market?

What are the market opportunities and threats faced by the vendors in the GlobalNanomedicine Market?

This report provides pinpoint analysis for changing competitive dynamics. It offers a forward-looking perspective on different factors driving or limiting market growth. It provides a five-year forecast assessed on the basis of how they progressive growth inNanomedicine Market is predicted to grow. It helps in understanding the key product segments and their future and helps in making informed business decisions by having complete insights of market and by making in-depth analysis of market segments.

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Gain detailed insights on theNanomedicine industry trends

Find complete analysis on the market status

Identify theNanomedicine market Counteropportunities and growth segments

Analyze competitive dynamics by evaluating business segments & product portfolios

Facilitate strategy planning and industry dynamics to enhance decision making

The report offers in-depth assessment of the growth and other aspects of theNanomedicine market in important countries (regions), including:

North America

Europe

Asia PacificCounter

Middle East & Africa

Latin America

America Country (United States, Canada)

South America

Asia Country (China, Japan, India, Korea)

Europe Country (Germany, UK, France, Italy)

Other Country (Middle East, Africa, GCC)

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TABLE OF CONTENT

1 Report Overview

2 Global Growth Trends

3 Market Share by Key Players

4 Breakdown Data by Type and Application

5 United States

6 Europe

7 China

8 Japan

9 Southeast Asia

10 India

11 Central & South America

12 International Players Profiles

13 Market Forecast 2020-2027

14 Analysts Viewpoints/Conclusions

15 Appendix

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(IMPACT OF COVID-19) Nanomedicine Market Research 2020 Next Big Thing | GE Healthcare, Johnson& Johnson, Mallinckrodt plc, Merck& Co. Inc.,...

Healthcare Nanotechnology (Nanomedicine) Market 2020-2024 | Latest Industry Updates, Projections, Consumption Analysis, Investment Cost, Profits Data…

This Healthcare Nanotechnology (Nanomedicine) Market research report provide business experts opinion with efficient information on Healthcare Nanotechnology (Nanomedicine) market growth rate, emerging business environments, and the latest business-centric applications. This Healthcare Nanotechnology (Nanomedicine) industry report lists and studies the leading participants also provide insights with strategic industry Analysis of the key factors influencing the market dynamics. Healthcare Nanotechnology (Nanomedicine) market report focuses on to describe and analyze the value, market share, market competition landscape, SWOT analysis, and development plans in the next few years. The report also offers an in-depth analysis of the Healthcare Nanotechnology (Nanomedicine) market with prime emphasis on factors such as drivers, restraints, trends, and opportunities.

Scope of the Report:

As per the , the healthcare nanotechnology (nanomedicine) market includes products that are nanoformulations of the existing drugs or new drugs or are nanobiomaterials. The market is segmented by its application in the medical field, as drug delivery, biomaterials, active implants, diagnostic imaging, tissue regeneration, and other applications. The market is also segmented by its use in the treatment of diseases, like cardiovascular diseases, oncological diseases, neurological diseases, orthopedic diseases, infectious diseases, and other diseases.<

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Key Market Trends:

The Growth of Nanomedicine is Expected to Provide High Opportunities for the Treatment of Neurological Diseases, Over the Forecast Period

A large number of brain disorders with neurological and psychological conditions result in short-term and long-term disabilities. Recent years observed a significant number of research studies being published on methods for the synthesis of nanoparticle-encapsulated drugs within in vivo and in vitro studies. The insufficient absorbance of oral drugs administered for a range of neurological conditions, such as Alzheimers disease, Parkinson disease, tumor, neuro-AIDS, among others, opens up the necessity of nanomedicine with stem cell therapy. Some of the registered nanoparticles for the complex CNS treatment are a gold nanoparticle, lipid nanoparticle, and chitosan nanoparticles.

Other than neurological diseases, research-based progress was found in the treatment of cancers, with the scientific communities identifying new metabolic pathways to find better drug combination using nanomedicine.

North America is Expected to Hold the Largest Share in the Market

In the United States, several companies are closely observing the developments in nanostructured materials across various applications in the healthcare industry, including medical devices, to improve efficiency and efficacy. In the United States, the National Nanotechnology Initiative (NNI), which was initiated in 2000, is among the supreme bodies that manage all nanotechnology-related activities. Under the NNI, several agencies are working in collaboration with companies and universities. For instance, nano-manufacturing in Small Business Innovation Research (SBIR) programs were developed for both commercial and public use. Companies are targeting the treatment of several cancer types and infectious diseases through immunotherapy, where nanoemulsion vaccines and drugs play a significant role. In the United States, one of the major challenges associated with nanotechnology is the ability to integrate nanoscale materials into new devices and systems, along with an application of novel properties at the nano-level. Thus, most of the companies are investing in R&D. Nanotechnology is likely to play a significant role in the delivery of drugs. In the recent strategic plan presented by the NNI in 2016, several programs were identified to further advance the research and development programs, over the forecast period.

Key Questions Answered in This Report:

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Detailed TOC of Healthcare Nanotechnology (Nanomedicine) Market 2019-2024:

1 INTRODUCTION1.1 Study Deliverables1.2 Study Assumptions1.3 Scope of the Study

2 RESEARCH METHODOLOGY

3 EXECUTIVE SUMMARY

4 MARKET DYNAMICS4.1 Market Overview4.2 Market Drivers4.2.1 Growing Prevalence of Cancer and Genetic and Cardiovascular Diseases4.2.2 Increasing Advancements in Nanoscale Technologies for Diagnostic Procedures4.2.3 Growing Preference for Personalized Medicines4.3 Market Restraints4.3.1 High Cost4.3.2 Stringent Regulations for Commercial Introduction4.4 Porters Five Forces Analysis4.4.1 Threat of New Entrants4.4.2 Bargaining Power of Buyers/Consumers4.4.3 Bargaining Power of Suppliers4.4.4 Threat of Substitute Products4.4.5 Intensity of Competitive Rivalry

5 MARKET SEGMENTATION5.1 By Application5.1.1 Drug Delivery5.1.2 Biomaterials5.1.3 Active Implants5.1.4 Diagnostic Imaging5.1.5 Tissue Regeneration5.1.6 Other Applications5.2 By Disease5.2.1 Cardiovascular Diseases5.2.2 Oncological Diseases5.2.3 Neurological Diseases5.2.4 Orthopedic Diseases5.2.5 Infectious Diseases5.2.6 Other Diseases5.3 Geography5.3.1 North America5.3.1.1 US5.3.1.2 Canada5.3.1.3 Mexico5.3.2 Europe5.3.2.1 France5.3.2.2 Germany5.3.2.3 UK5.3.2.4 Italy5.3.2.5 Spain5.3.2.6 Rest of Europe5.3.3 Asia-Pacific5.3.3.1 China5.3.3.2 Japan5.3.3.3 India5.3.3.4 Australia5.3.3.5 South Korea5.3.3.6 Rest of Asia-Pacific5.3.4 Middle East & Africa5.3.4.1 GCC5.3.4.2 South Africa5.3.4.3 Rest of Middle East & Africa5.3.5 South America5.3.5.1 Brazil5.3.5.2 Argentina5.3.5.3 Rest of South America

6 COMPETITIVE LANDSCAPE6.1 Company Profiles6.1.1 Sanofi SA6.1.2 Celegene Corporation6.1.3 CytImmune Sciences Inc.6.1.4 Johnson & Johnson6.1.5 Luminex Corporation6.1.6 Merck & Co. Inc.6.1.7 Nanobiotix6.1.8 Pfizer Inc.6.1.9 Starpharma Holdings Limited6.1.10 Taiwan Liposome Company Ltd

7 MARKET OPPORTUNITIES AND FUTURE TRENDS

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Healthcare Nanotechnology (Nanomedicine) Market 2020-2024 | Latest Industry Updates, Projections, Consumption Analysis, Investment Cost, Profits Data...

Nanoparticle Therapy Might Help Reduce Brain Swelling in… : Neurology Today – LWW Journals

Article In Brief

Mice with an open- and closed-traumatic brain injury were injected with immunomodulatory nanoparticles that reduced brain swelling and damage on MRI.

Investigators used a novel approach to prevent the swelling that can occur after traumatic brain injury (TBI) in a mouse model: they injected nanoparticles that trick white blood cells into going after them instead of rushing to the injured brain and causing an inflammatory and immune response.

Mice with TBI that were given three injections of the immunomodulatory nanoparticles beginning two to three hours after injury showed less brain swelling and damage on MRI as compared with mice with TBI that did not get the nanoparticles; the treated mice also performed better on functional tests.

The immunomodulatory nanoparticle treatment, if further proven in preclinical trials and human trials, would not undo damage from the initial injury to the brain. But it could help prevent the body from setting off a cascade of immune and inflammatory cells in reaction to the injury, which in turn can cause brain swelling and even more damage to brain tissue.

We certainly haven't gone and magically prevented that initial damage, said Jack Kessler, MD, professor of neurology at Northwestern University Feinberg School of Medicine and the senior author of the paper. What we can do is prevent the secondary damage, which is substantial.

Predicting which TBI patients will develop edema of the brain isn't easy, so having a preventive treatment like the nanoparticles that could be administered upfront could be life-altering, Dr. Kessler said.

He said some patients with head injuries come into the hospital walking and talking, but then their brain swells, and they die.

According to background in the study, published January 10 online in Annals of Neurology, each year more than 2.5 million people in the US have a traumatic brain TBI and more than five million Americans live with at least one sequela of TBI.

After the primary injury, there is substantial secondary injury attributable to infiltrating immune cells, cytokine release, reactive oxygen species, excitotoxicity, and other mechanisms, the study authors wrote. Despite many preclinical and clinical trials to limit such secondary damage, no successful therapies have emerged.

The nanoparticles tested in the mouse experiments are made of material used in biodegradable sutures. The paper specifically described the particles as highly negatively charged, 500 nm-diameter particles composed of the Food and Drug Administration (FDA)-approved biodegradable biopolymer carboxylated poly (lactic-co glycolic) acid.

The nanoparticles (IMPs), which seem like foreign invaders to the body's immune system, attract the attention of large white blood cells known as monocytes, which have been implicated in the secondary damage that occurs with TBI.

IMPs bind to the macrophage receptor with collagenous structure (MARCO) on monocytes and monocytes bound to IMPs no longer home to sites of inflammation but rather are sequestered in the spleen, where the cells die, the study authors wrote.

The mouse study involved two types of head injury. In some of the mice, the researchers performed a craniotomy to create a controlled cortical impact. Other mice received a closed head injury involving a direct blow to the head. Both types of injuries were meant to mimic what occurs in humans with TBI.

Injections of the nanoparticles were given two to three hours after the brain injury, and again at 24 hours and 48 hours post-injury. Control animals with similar brain injuries were given saline solution at the same time points.

Outcomes for the mice who received the nanoparticles were better by multiple measures, including MRI and a motor function test called the ladder rung walking test that is used in mouse experiments.

IMP administration resulted in remarkable preservation of both tissue and neurological function, in both models of head injury, the paper said. After acute treatment, there was a reduction in the number of immune cells infiltrating into the brain, mitigation of the inflammatory status of the infiltrating cells, improved electrophysiological visual function, improved long-term motor behavior, reduced edema formation as assessed by magnetic resonance imaging, and reduced lesion volumes on anatomic examination.

Dr. Kessler said that in the case of mice with an open head injury, the size of their brain lesion was 50 percent smaller in the treated animals compared with those that did not get the nanoparticles.

He said MRI showed significantly less brain swelling and less compression of the ventricles, both signs that secondary damage was minimized.

Dr. Kessler said that right now the only recourse for severe brain swelling is to do a craniotomy to relieve pressure in the skull.

He said one of the appeals of the nanoparticle treatment is that an emergency medical technician could do it in the field or the emergency room personnel could inject it.

But Dr. Kessler is also cautious about too many predications based on a pre-clinical study, saying he is fond of telling medical students that if I had a nickel for every mouse we cured, I'd be a rich man.

Sripadh Sharma, PhD, an MD-PhD student at Northwestern and the study's first author, said the nanoparticle therapy needs to be tested further in animal models before it could go into human testing. The researchers also want to learn more about how the nanoparticles bring about a reduced immune response in the body.

Dr. Sharma noted that while immune responses are a good thing in the face of injury or infection, sometimes nature doesn't always get it right, so too much of a good thing is a bad thing. And that can be the case with TBI.

He said it has been shown by another collaborator on the study, Stephen Miller, PhD, that when the scavenger receptors on the monocytes detect the light negative charge of the nanoparticles, the monocytes engulf and bind to the particles and apoptose in the spleen instead of going to the site of injury.

More studies need to be done to optimize what dose and what time these particles need to be given following a head injury, said Dr. Sharma.

Similar nanoparticle therapy is being tested for other medical conditions, including celiac disease and myocardial infarction, Dr. Kessler said.

Michael J. Schneck, MD, FAAN, professor of neurology (and neurosurgery) at Loyola University Chicago, said the study was well-designed and thorough, using two different head injury models and multiple outcome measures, including brain imaging, functional testing, and brain tissue analysis. Dr. Schneck said the paper made him wonder whether a similar approach using immune-modulating nanoparticles could reduce inflammatory-related damage following stroke and spinal cord injury.

Dr. Schneck said the concept of trying to dampen the immune response after TBI to prevent edema is not new, but the Northwestern researchers took the idea in a new direction. The nanoparticle therapy is particularly intriguing, he said, because it is fairly simple and involves the use of a material that is already approved by the US FDA, which could mean that it would take less time to move the therapy from the laboratory into clinical trials.

This is a very elegant study with interesting translational potential, he said. But it is a mouse model and its application to (human) TBI and other forms of central nervous system injury remains to be validated.

Jiangbing Zhou, PhD, associate professor of neurosurgery and biomedical engineering at Yale University, said that as someone who does research in the field of nanomedicine, he was surprised by the study's findings and wants to understand how this simple formulation particle could achieve this marked efficacy.

The study looks very exciting, but I want to know more about the mechanism, said Dr. Zhou, whose research focuses on developing translational nanomedicine, gene therapy, and stem cell therapy for neurological disorders including TBI.

He had these and other questions about the study: Why do the particles interact specifically with the inflammatory monocytes but not the others? How do the particles, which are made of safe biomaterials, efficiently kill the inflammatory monocytes in the spleen? What is happening and why?

Javier Crdenas, MD, director of the Barrow Concussion and Brain Injury Center at the Barrow Neurological Institute, said the study on the immune-modulating nanoparticle therapy for TBI was very promising, though he stressed that he is always cautiously optimistic when he sees a mouse study.

It is definitely a novel approach to addressing the secondary sequelae of brain injury and they might have something that minimizes that and hopefully improves outcomes, Dr. Crdenas said.

He said the study also raises some questions, including how the immune-modulating approach would fare in patients who have multiple injuries, not just to the head.

Dr. Crdenas said brain injuries often do not happen in isolation, with patients also having broken bones, lacerations, and other organ damage.

We don't know how this (nanoparticle treatment) would affect other organs, other immune responses elsewhere in the body, he said.

Dr. Crdenas said the field of TBI research has been disappointed before by studies of new therapies that looked promising in animal models and clinical testing but ultimately failed. He noted, for instance, that progesterone and hypothermia did not turn out to be good at preventing brain swelling.

We will wait and see, he said of the nanoparticles.

Drs. Sharma, Schneck, Zhou, and Crdenas had no disclosures.

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Nanoparticle Therapy Might Help Reduce Brain Swelling in... : Neurology Today - LWW Journals

Global Nanomedicine Market Outlook, Strategies, Manufacturers, Countries, Type and Application, Global Forecast To 2026 – Stop Smoking Lounge

The latest report on Global Nanomedicine Market now available at Report Ocean, explains the contemporary and upcoming trends besides details associated with the regional landscape of the nanomedicine market that includes several regions. The report further emphasizes intricate details regarding the demand and supply analysis, contributions by leading industry players and market share growth of the nanomedicine market industry. Comprehensive secondary research was done to collect information on the market and its parent and ancillary markets. Further, primary research was performed to validate the assumptions and findings obtained from secondary research with key opinion leaders (KOL) and industry experts.

The report is a universal account of the major insights related to the geographical landscape of this business as well as the companies that have a reputable status in the nanomedicine market.

Request Free Sample Report athttps://www.reportocean.com/industry-verticals/sample-request?report_id=IR192

In this report, we analyze the nanomedicine market industry from two aspects.

1. Production In terms of its production, we analyze the production, revenue, gross margin of its main manufacturers and the unit price that they offer in different regions from 2014 to 2019.

2. Consumption In terms of consumption, we analyze the consumption volume, consumption value, sale price, import and export in different regions from 2014 to 2019.

We also make a prediction of its production and consumption in coming 2020-2026.

At the same time, we classify different nanomedicine market based on their definitions. Upstream raw materials, equipment and downstream consumers analysis is also carried out. It also focuses on market influencing factors, competitive landscape, data, trends, information, and exclusive vital statistics of the market.

The market study focuses on various key parameters that include:

Market Segmentation

Regional Segmentation

In-Depth study of Market Determinants

360-Degree Economic Analysis

Regulatory Analysis

Company Profiling and others

Competitive Landscape:

The competitive analysis of major market players is another notable feature of the nanomedicine market industry report; it identifies direct or indirect competitors in the market. The report offers company profile of market players alongside product picture and its specifications, nanomedicine market industry market plans, and technology adopted by them, future development plans. In addition, strength and weaknesses analysis of nanomedicine market industry competitive firms gives competitive advantages so that the efficiency and the productivity of companies are improved.

Market Segmentation:

The segmentation is used to decide the target market into smaller sections or segments like product type, application, and geographical regions to optimize marketing strategies, advertising technique and global as well as regional sales efforts of nanomedicine market. The common characters are also being considered for segmentation such as global market share, common interests, worldwide demand and supply of Access Control devices. Moreover, the report compares the production value and growth rate of Global Nanomedicine Market across different geographies.

This report studies the top producers and consumers, focuses on product capacity, production, value, consumption, market share and growth opportunity in these key regions, covering

North America (United States, Canada and Mexico)

Europe (Germany, France, UK, Russia and Italy)

Asia-Pacific (China, Japan, Korea, India and Southeast Asia)

South America (Brazil, Argentina, Colombia)

Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)

The research methodology adopted by analysts to study the market include inputs derived from industry professionals across the value chain and various other secondary research methods, along with primary research as a major tool for market study.

Some of the Major Highlights of TOC covers:

Executive Summary

Global Nanomedicine Market Insights

Global Nanomedicine Market forecast by different Segments and Regions

Manufacturing Cost Structure Analysis

Development and Manufacturing Plants Analysis of Global Nanomedicine Market

Key Figures of Major Manufacturers

Why to purchase this report:

The report would provide an in-depth analysis on the current and future market trends

Analysis on global, regional and country level markets

Key strategic initiatives taken by major players operating in the market along with ranking analysis for the key players

Analysis based on historical information along with the current trends to estimate the future of the market

Analysis of the impact of constantly changing global market scenarios

3 months analyst support along with the Market Estimate sheet in excels.

For more information and discount on this report, ask your query at:https://www.reportocean.com/industry-verticals/sample-request?report_id=IR192

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Global Nanomedicine Market Outlook, Strategies, Manufacturers, Countries, Type and Application, Global Forecast To 2026 - Stop Smoking Lounge

Nanomedicine Market 2019 Industry Outlook, Comprehensive Insights, Growth and Forecast 2025 – Med News Ledger

The Nanomedicine research report is a valuable source of data for business strategists. It provides the Nanomedicine overview with growth analysis and historical and futuristic cost revenue demand and supply data. The research analysis provides an elaborative description of the value chain and distributor analysis.

Request Sample Copy of This Report: @https://99marketresearch.com/global-nanomedicine-market-size-status-and-forecast-2019-2025/102924/#Free-Sample-Report

The Nanomedicine market study provides comprehensive data that enhance the understanding, scope and application of this report.

The report provides a basic overview of the industry including definitions and classifications. The Nanomedicine analysis is provided for the international markets including development trends, competitive landscape analysis, and key regions development status.

Prominent players of Nanomedicine market:

Product Type Coverage (Market Size & Forecast, Major Company of Product Type etc):

Application Coverage (Market Size & Forecast, Different Demand Market by Region, Main Consumer Profile etc.):

Development policies and plans are discussed as well as manufacturing processes and cost structures are also analyzed. This report also states import/export consumption, supply and demand Figures, cost, price, revenue and gross margins.

This report studies the Nanomedicine status and outlook of Global and major regions, from angles of players, countries, product types and end industries; this report analyses the top players in global market, and splits the Nanomedicine By product type and applications/end industries.

Read Detailed Index of full Research Study at @ https://99marketresearch.com/global-nanomedicine-market-size-status-and-forecast-2019-2025/102924/

To comprehend 2018-2026 Nanomedicine dynamics in the world mainly, the worldwide 2018-2026 Nanomedicine is analyzed across major global regions. Nanomedicine Also provides customized specific regional and country-level reports for the following areas.

North America: United States, Canada, and Mexico.

South & Central America: Argentina, Chile, and Brazil.

Middle East & Africa: Saudi Arabia, UAE, etc

The study objectives of this report are:

To study and forecast the market size of Nanomedicine

To analyze the global key players, SWOT analysis, value and global market share for top players.

To define, describe and forecast the market by type, end-use and region.

To analyses and compare the market status and forecast among global major regions.

To analyses the global key regions market potential and advantage, opportunity and challenge, restraints and risks.

To identify significant trends and factors driving or inhibiting market growth.

TOC-

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Nanomedicine Market 2019 Industry Outlook, Comprehensive Insights, Growth and Forecast 2025 - Med News Ledger

Functionalized Gold and Silver Bimetallic Nanoparticles Using Deinococ | IJN – Dove Medical Press

Yulan Weng, 1 Jiulong Li, 1 Xingcheng Ding, 2 Binqiang Wang, 1 Shang Dai, 1 Yulong Zhou, 3 Renjiang Pang, 1 Ye Zhao, 1 Hong Xu, 1 Bing Tian, 1, 3 Yuejin Hua 1

1MOE Key Laboratory of Biosystems Homeostasis & Protection, Zhejiang University, Hangzhou, Peoples Republic of China; 2Zhejiang Runtu Chemical Research Institute, Shaoxing, Peoples Republic of China; 3Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, School of Chemistry and Chemical Engineering, Shihezi University, Shihezi, Xinjiang, Peoples Republic of China

Correspondence: Bing TianZhejiang University Zijingang Campus West Part, A403 Biophysics Building, 866 Yuhangtang Road, Hangzhou 310058, Peoples Republic of ChinaTel/Fax +86-571-86971215Email tianbing@zju.edu.cn

Background: Biodegradation of toxic organic dye using nanomaterial-based microbial biocatalyst is an ecofriendly and promising technique.Materials and Methods: Here, we have investigated the novel properties of functionalized Au-Ag bimetallic nanoparticles using extremophilic Deinococcus radiodurans proteins (Drp-Au-AgNPs) and their degradation efficiency on the toxic triphenylmethane dye malachite green (MG).Results and Discussion: The prepared Drp-Au-AgNPs with an average particle size of 149.8 nm were capped by proteins through groups including hydroxyl and amide. Drp-Au-AgNPs demonstrated greater degradation ability (83.68%) of MG than D. radiodurans cells and monometallic AuNPs. The major degradation product was identified as 4-(dimethylamino) benzophenone, which is less toxic than MG. The degradation of MG was mainly attributed to the capping proteins on Drp-Au-AgNPs. The bimetallic NPs could be reused and maintained MG degradation ability (> 64%) after 2 cycles.Conclusion: These results suggest that the easilyprepared Drp-Au-AgNPs have potential applications as novel nanomedicine for MG detoxification, and nanomaterial for biotreatment of a toxic polyphenyl dye-containing wastewater.

Keywords: bimetallic nanoparticles, Deinococcus radiodurans, biodegradation, toxic triphenylmethane dye, malachite green, detoxification

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

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Functionalized Gold and Silver Bimetallic Nanoparticles Using Deinococ | IJN - Dove Medical Press

Yuri Svidinenko Nanomedicine Medical Animation including Oncology – Video


Yuri Svidinenko Nanomedicine Medical Animation including Oncology
Yuri is a noted medical illustrator who specializes in NanoMedicine, and Oncology, and speaks about the way he visualizes, and creates his excellent animated illustrations of Nanomedince and ...

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Yuri Svidinenko Nanomedicine Medical Animation including Oncology - Video

Global Nanomedicine Market 2019 Industry Outlook, Comprehensive Insights, Growth and Forecast 2024 – The Chicago Sentinel

MarketandResearch.bizhas recently announced the addition of new research report to its repository named,GlobalNanomedicine Market Research 2019 by Manufacturers, Regions, Countries, Types and Applications, Forecast to 2024. It provides a clear understanding of the market dynamics by studying the historical data and analyzing the current market situation. It aims to chalk the route of the market for the coming few years. It gives a comprehensive synopsis of the market picture including market overview, introduction, classification, market dynamics,and market size.

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TheNanomedicinemarket research report includes a separate section which specifies key players profiles allowing understanding the pricing structure, cost,Nanomedicinecompany basic information, their contact details,and product category.

Main leading players in theNanomedicineMarket Are:, Combimatrix, Ablynx, Abraxis Bioscience, Celgene, Mallinckrodt, Arrowhead Research, GE Healthcare, Merck, Pfizer, Nanosphere, Epeius Biotechnologies, Cytimmune Sciences, Nanospectra Biosciences, ,

GlobalNanomedicinehas witnessed gradual growth in recent years and is expected to witness steady growth in the forecast period.In this report, theNanomedicinemarket is valued at USD XX million in 2017 and is expected to reach USD XX million by the end of 2024, growing at a CAGR of XX% between 2019 and 2024.

TheNanomedicinereport contains brief information on these trends that can help the businesses operating in the industry to know constituents of the market and strategize for their business expansion accordingly. Moreover, various rudimentary aspects of theNanomedicinemarket such as market size, industry share, growth, key segments, and CAGR are also added in the report. The next section of the report serves detailed overview ofNanomedicineproduct specification, product type, product scope, and production analysis with key factors such as capacity, production, revenue, price and gross margin.

The notable feature of this report is that it presents an all-enclosing view of theNanomedicinemarket based on its segmentation, with respect to types, application, end-users, products, and geography.

The report executes the great study of capacity, production, revenue, price, gross margin, technology, demand-supply, consumption, import, export, market drivers and opportunities.It also discusseslimitations, risks, and challenges which will decide the standing future of the market all over the world.

The Study Report Provides In-depth Analysis On:

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Furthermore, manufacturing cost structure combines analysis of key raw materials, their price trends along with labor cost and manufacturing expenses. For market chain analysis, the report covers upstream raw materials, equipment, downstream buyers, marketing channels, and market development trend which more deeply include important information on key distributors/traders, major raw materials suppliers and contact information, major manufacturing equipment suppliers, major suppliers, and key consumers.

The report profiles SWOT analysis and market strategies of the key players. Any individual or organization interested in the report can greatly benefit from it. The market research data added in the study is the result of extensive primary and secondary research activities, surveys, personal interviews, and inputs from industry expert.

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Global Nanomedicine Market 2019 Industry Outlook, Comprehensive Insights, Growth and Forecast 2024 - The Chicago Sentinel

Automation increases productivity in materials science by 384 times, say researchers – Robotics and Automation News

An automated method of conducting materials science research can increase productivity by 384 times when compared to a human, according to researchers.

The robot-plus-software system also makes it easier for people who are not expert researchers or scientists to create new materials.

A Rutgers-led team of engineers has developed an automated way to produce polymers, making it much easier to create advanced materials aimed at improving human health.

The team says this innovation is a critical step in pushing the limits for researchers who want to explore large libraries of polymers, including plastics and fibers, for chemical and biological applications such as drugs and regenerative medicine through tissue engineering.

While a human researcher may be able to make a few polymers a day, the new automated system featuring custom software and a liquid-handling robot can create up to 384 different polymers at once, a huge increase over current methods.

Synthetic polymers are widely used in advanced materials with special properties, and their continued development is crucial to new technologies, according to a study in the journal Advanced Intelligent Systems. Such technologies include diagnostics, medical devices, electronics, sensors, robots and lighting.

Senior author Adam J. Gormley, an assistant professor in the Department of Biomedical Engineering in the School of Engineering at Rutgers UniversityNew Brunswick, says: Typically, researchers synthesize polymers in highly controlled environments, limiting the development of large libraries of complex materials.

By automating polymer synthesis and using a robotic platform, it is now possible to rapidly create a multitude of unique materials.

Robotics has automated many ways to make materials as well as discover and develop drugs.

But synthesizing polymers remains challenging because most chemical reactions are extremely sensitive to oxygen and cant be done without removing it during production.

The Gormley labs open-air robotics platform carries out polymer synthesis reactions that tolerate oxygen.

The group developed custom software that allows a liquid handling robot to interpret polymer designs made on a computer and carry out every step of the chemical reaction.

One benefit is that the new automated system makes it easier for non-experts to create polymers.

The lead author is Matthew Tamasi, a Rutgers doctoral student. Co-authors include doctoral student Shashank Kosuri and undergraduate student Jason DiStefano.

A researcher at the Australian Centre for Nanomedicine and Centre for Advanced Macromolecular Design contributed to the study, which was funded by the New Jersey Health Foundation.

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Automation increases productivity in materials science by 384 times, say researchers - Robotics and Automation News

How IBM Is Using Nanotechnology To Tackle MRSA And HIV

While giving a talk at a conference in Australia in the mid-2000s, IBM Research's lead scientist for the advanced organic materials group, James Hedrick, had an encounter that would make him rethink his career. At one point, Hedrick--who holds more than 100patents--took a question from a woman in the audience. It wasn't what he was expecting. "Why are you wasting your time with all this electronics stuff?" asked Dr. Yi Yan Yang, who works at the Institute of Bioengineering and Nanotechnology in Singapore. "You need to work with me." That evening, Yang filled Hedrick in on how she was using high-tech nanomaterials for medical purposes. "She was absolutely right," Hedrick recalls. "I was wasting time doing just semiconductors."

The result was IBM's unusual nanomedicine program, an ongoing collaboration between Hedrick's team at the Almaden, Californiabased IBM Research and Yang's group of researchers in Singapore. The project is tackling a range of ambitious projects: creating better antimicrobial and antifungal agents, new methods of drug delivery, and novel ways of combating such diseases as HIV/AIDS and tuberculosis. It may seem strange that computer-hardware giant IBM is pouring resources into experimental nanomedicine, but it's part of a larger trend within the company. "There is a huge group of IBMers who think we should be using our intellectual know-how to address global problems," says Spike Narayan, director of IBM Research's science and technology group. "As we've pushed the boundaries and engaged with other disciplines, we've found that some of our capabilities in materials and nanotechnology are very relevant in addressing challenges related to water, energy, the environment, and health care. That's the motivation."

Although it has yet to yield a commercial product (Narayan says several joint ventures are in the works), the program also makes sense from a business perspective. Even as the price of computing power keeps falling for consumers, R&D and manufacturing costs are steadily increasing for semiconductor producers. That's squeezing profits: Between 2000 and 2012, IBM's hardware business went from contributing 35% of the company's pretax income to just 14%. Perhaps that's why in February 2014, Big Blue reportedly hired Goldman Sachs to explore a potential sale of its semiconductor operation. New areas such as nanomedicine could offer a way for IBM to continue profiting from its cutting-edge research in nanomaterials even if it does get out of semiconductors. "Now we have an ITcentric focus," says Narayan, "but there's no reason we couldn't be more materials-focused, providing enabling technology for other companies."

The nanomedicine group's first big breakthrough was the creation of polymer-based nanoparticles that can target and kill MRSA, a potentially deadly drug-resistant bacterium. The nanoparticles engineered by the IBMSingapore team--dubbed "ninja particles"--use electrostatic attraction to target infected cells. Because the polymers used to create ninja particles are biodegradable, they pass out of the body once they've done their job. While the particles haven't yet been submitted for FDA approval, IBM is working with pharmaceutical, consumer-products, and medical-device companies to explore applications.

In the past year, the pace of innovation has accelerated. The Hedrick-Yang group published a paper in December that describes a method for breaking down PET--the stuff plastic bottles are made of--and reconstructing it into a nanofiber that can kill fungal infections on contact. In the lab, these nanofibers were more effective in fewer doses than conventional antifungal drugs, in addition to being nontoxic and biodegradable. Since the polymers used in both chip manufacture and nanomedicine are generally derived from petroleum, the ability to instead start from recycled material could reduce industrial consumption of oil and gas while providing a new use for plastic waste.

Hedrick and his partners have also made headway in drug delivery, coaxing nanoparticles to self-assemble into a gel-like material that can encapsulate molecules of a drug and release them at a particular location in the body over an extended period of time. When the Singapore team encapsulated the breast cancer drug Herceptin into the hydrogel and injected it into animals, their tumors shrank more than 75%, and the drug remained active and effective in the bloodstream for a month after a single injection. Tumors in animals given a regular IV injection of the drug didn't shrink at all, according to results published in November 2013.

Potential medical and consumer applications for materials coming out of the nanomedicine program are practically limitless: they could be injected; applied as a topical gel to treat wounds and infections; included in products such as soap, hand sanitizer, and shampoo; or applied as a germ-fighting coating on everything from medical devices to cutting boards and toothbrushes. Before they can be commercialized, all of these products will require approval by either the EPA or FDA, so rather than bring products to market on its own, IBM will aim to collaborate with partners that have more regulatory and manufacturing expertise. "Increasingly, in these nontraditional, interdisciplinary spaces, no one has all the capabilities," says Narayan. "As we jointly develop [intellectual property], there will be all kinds of royalty and other revenue streams coming out." The first product to make it out of the lab will most likely be an antimicrobial material to clean surfaces in hospitals.

For Hedrick, pivoting from his comfort zone in silicon hardware has been a learning process. "When I first started this, we went to some major pharma companies, and I got my backside handed to me pretty quick," he says. "Now I feel very comfortable going into a room with scientists and executives and rattling off proteins and numbers and names. A lot of the time [when he's not in meetings], though--I kid you not--I have Wikipedia open on my phone."

Inspired in part by the recent launch of an IBM Research lab in Africa, Hedrick is excited about deploying nanomaterials to fight illnesses that disproportionately afflict the region, including tuberculosis, dengue fever, and HIV. He also hopes to look at ways to use nanocontainers to deliver drugs across the blood-brain barrier--a major challenge in treating conditions such as Alzheimer's and Parkinson's. "Even three years ago, I would have been surprised by what we've been able to accomplish so far," he says. "IBM Research has given us significant latitude and freedom. Because they've always kept the lights on, we're able to address these grand challenges in a unique way."

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How IBM Is Using Nanotechnology To Tackle MRSA And HIV

Nanomedicine Market Healthy Pace throughout the Forecast by 2023 – Crypto News Byte

Overview:

Nanomedicine is an offshoot of nanotechnology, and refers to highly-specific medical intervention at the molecular scale for curing diseases or repairing damaged tissues. Nanomedicine uses nano-sized tools for the diagnosis, prevention and treatment of disease, and to gain increased understanding of the complex underlying pathophysiology of the disease. It involves three nanotechnology areas of diagnosis, imaging agents, and drug delivery with nanoparticles in the 11,000 nm range, biochips, and polymer therapeutics.

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Majority of nanomedicines prescribedcurrently, allow oral drug delivery and its demand is increasing significantly. Although these nanovectors are designed to translocate across the gastrointestinal tract, lung, and bloodbrain barrier, the amount of drug transferred to the organ is lower than 1%; therefore improvements are challenging. Nanomedicines are designed to maximize the benefit/risk ratio, and their toxicity must be evaluated not only by sufficiently long term in vitro and in vivo studies, but also pass multiple clinical studies.

Market Analysis:

The Global Nanomedicine Market is estimated to witness a CAGR of 17.1% during the forecast period 20172023. The nanomedicine market is analyzed based on two segments therapeutic applications and regions.

The major drivers of the nanomedicine market include its application in various therapeutic areas, increasing R&D studies about nanorobots in this segment, and significant investments in clinical trials by the government as well as private sector. The Oncology segment is the major therapeutic area for nanomedicine application, which comprised more than 35% of the total market share in 2016. A major focus in this segment is expected to drive the growth of the nanomedicine market in the future.

Regional Analysis:

The regions covered in the report are the Americas, Europe, Asia Pacific, and Rest of the World (ROW). The Americas is set to be the leading region for the nanomedicine market growth followed by Europe. The Asia Pacific and ROW are set to be the emerging regions. Japan is set to be the most attractive destination and in Africa, the popularity and the usage of various nano-drugs are expected to increase in the coming years. The major countries covered in this report are the US, Germany, Japan, and Others.

Therapeutic Application Analysis:

Nanomedicines are used as fluorescent markers for diagnostic and screening purposes. Moreover, nanomedicines are introducing new therapeutic opportunities for a large number of agents that cannot be used effectively as conventional oral formulations due to poor bioavailability. The therapeutic areas for nanomedicine application are Oncology, Cardiovascular, Neurology, Anti-inflammatory, Anti-infectives, and various other areas. Globally, the industry players are focusing significantly on R&D to gain approval for various clinical trials for future nano-drugs to be commercially available in the market. The FDA should be relatively prepared for some of the earliest and most basic applications of nanomedicine in areas such as gene therapy and tissue engineering. The more advanced applications of nanomedicine will pose unique challenges in terms of classification and maintenance of scientific expertise.

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Key Players:

Merck & Co. Inc., Hoffmann-La Roche Ltd., Gilead Sciences Inc., Novartis AG, Amgen Inc., Pfizer Inc., Eli Lilly and Company, Sanofi, Nanobiotix SA, UCB SA and other predominate & niche players.

Competitive Analysis:

At present, the nanomedicine market is at a nascent stage but, a lot of new players are entering the market as it holds huge business opportunities. Especially, big players along with the collaboration with other SMBs for clinical trials of nanoparticles and compounds are coming with new commercial targeted drugs in the market and they are expecting a double-digit growth in the upcoming years. Significant investments in R&D in this market are expected to increase and collaborations, merger & acquisition activities are expected to continue.

Benefits:

The report provides complete details about the usage and adoption rate of nanomedicines in various therapeutic verticals and regions. With that, key stakeholders can know about the major trends, drivers, investments, vertical players initiatives, government initiatives towards the nanomedicine adoption in the upcoming years along with the details of commercial drugs available in the market. Moreover, the report provides details about the major challenges that are going to impact on the market growth. Additionally, the report gives the complete details about the key business opportunities to key stakeholders to expand their business and capture the revenue in the specific verticals to analyze before investing or expanding the business in this market.

Report Analysis@ https://www.trendsmarketresearch.com/report/analysis/IR/nanomedicine-market

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Nanomedicine Market Healthy Pace throughout the Forecast by 2023 - Crypto News Byte

World Pancreatic Cancer Day: increasing awareness and inspiring action – UNSW Newsroom

Pancreatic cancer is an insidious disease itis often diagnosedat an advanced stage, with about 90% of patients dying within five years of diagnosis.New projections suggest pancreatic cancer will be the second leading cause of cancer mortality by 2025.

This World Pancreatic Cancer Day, we are celebrating some of the many UNSWresearchers who are dedicated to changing those statistics. Cancers with poor outcomes like pancreatic cancer are a key focus area in UNSW Medicine's cancer theme.

Associate Professor Phillips is the Head of the Pancreatic Cancer Translational Research Group and Deputy Director of the Adult Cancer Program at the Lowy Cancer Research Centre at UNSW Medicine.

This year, A/Prof Phillips was a key driver in establishing the Pancreatic Cancer Research Hub, which aims to double the survival of patients with pancreatic cancer by 2030.

She says World Pancreatic Cancer Day is a powerful advocacy event to increase community and government awareness of pancreatic cancer.

It is also a time to reflect on the progress we have made in understanding this terrible disease and focus on the next steps to overcome current clinical challenges to ensure our research efforts bridge the gap and, as in other cancers, improve the outcomes for our patients with pancreatic cancer.

I know that we are on the brink of overturning the unacceptable statistics. Uniting researchers with the community who, unlike in other cancers, dont often get to be a strong voice advocating for themselves and Government will ensure Australian researchers continue to make positive change for pancreatic cancer patients globally.

A/Prof Phillips group has developed a novel cutting-edge way to keep pieces of human pancreatic tumours alive in the laboratory for two weeks after surgical resection.

Our capacity to grow human tumour tissue in the laboratory provides a valuable new clinical tool to test how a patients tumour responds to different chemotherapies and has the potential to immediately inform patient treatment options. Our unique tumour model is superior to other models because it is human in origin and it contains the complex tumour environment present in patients.

In 2016 A/Prof Phillips had a major breakthrough, successfully developing a novel nanomedicine a tiny drug delivery vehicle consisting of a state-of-the-art nanoparticle that can package gene therapy to inhibit any tumour-promoting gene in pancreatic cancer.

With the generous support from the Brian O'Neill Pancreatic Cancer Fundraising Dinner held last night the team will be able to perform essential preclinical studies to test the therapeutic potential of their nano-gene therapy in combination with a clinically approved drug. They also plan on using their expertise to improve the bioavailability of the clinically approved drugs using a nanomedicine approach.

Professor Minoti Apte was the first in the world to isolate and characterise pancreatic stellate cells, a cell type that is now known to play a major role in the progression of both chronic pancreatitis and pancreatic cancer. Coming up with ways to target these cells to prevent them from doing harm is now a major focus of her teams research.

The group has now shown that interrupting the cross-talk between cancer cells and surrounding cells in the microenvironment by targeting a certain signalling pathway reduces tumour growth and eliminates metastasis in early as well as advanced pre-clinical models of pancreatic cancer.

We have also shown that targeting this pathway reduces the risk of recurrence and progression after surgical resection of pancreatic cancer in a mouse model, and are currently working on possible pathways to take our laboratory findings to the clinic, Professor Apte says.

To me, World Pancreatic Cancer Day is a great opportunity to raise awareness in the community about this deadly cancer, but it is also a day to admire the courage and resilience of patients and their carers. These are the people that spur us researchers on to continue working hard to develop new therapeutic approaches to improve outcomes.

Last year, Professor Apte received the Gastroenterological Society of Australia (GESA) Distinguished Researcher Prize 2018. In 2014 she was awarded the Medal of the Order of Australia (OAM), after being named the NSW Woman of the Year in 2015. She was also the 2016 recipient of the Professor Rob Sutherland AO Make a Difference Award at the NSW Premiers Awards for Outstanding Cancer Research an award that recognises highly successful research that is actively changing cancer treatment and improving patient survival.

Dr Angelica Merlot, who is based at the Childrens Cancer Institute, focuses her research on developing new anti-cancer drugs that target drug resistance and suppress cancer spread.

This year, the cancer researcher has won the 2019 NSW Young Woman of the Year award for her achievements and research into treatments for pancreatic and brain cancer. She also won a 2019 Young Tall Poppy Science Award and the 2019 NSW Early Career Researcher of the Year (Biological Sciences) at the NSW Premiers Prizes for Science & Engineering.

Dr Merlot says today is an important day to raise awareness about one of the world's toughest cancers.

This is crucial as it broadens community knowledge, inspires action and supports further research funding for this cancer. It's also a time to remember those whom we have lost and those currently fighting this disease, she says.

Although we've seen a small improvement in the current survival rate, a lot of progress is still required. Further translational research means that there is a greater likelihood that the survival rates can be increased and the journey and treatment of those affected by the cancer can be improved.

Dr Merlot became focused on cancer research as an undergraduate. Her interest in aggressive cancers, such as pancreatic and brain cancer, was motivated by lack of improvement in survival rates over the past decades, largely due to late diagnosis, a lack of screening programs, low awareness of symptoms and a lack of treatment options.

After moving to UNSW Medicine as a Scientia Fellow in 2018, Dr Merlot focused on understanding the mechanisms by which cancer cells grow and adapt to their environment, why drugs become less effective and the development of nanoparticles to improve drug delivery.

Dr Merlots current projects are investigating part of a human cell called the endoplasmic reticulum (ER). The ER is a type of organelle, or subunit within a cell, that has been shown to help cancers grow, spread and develop drug resistance.

Dr Ying Zhu will lead a team of researchers from UNSW to discover much needed early detection methods for pancreatic cancer patients: the UNSW Medicine researcher today received $100,000 grant from the Avner Pancreatic Cancer Foundation. A/Prof Phillips is a co-investigator on this grant.

As current approaches to this research are time and labour intensive, the team will develop an integrated and small device based on nanotechnology for rapid and sensitive exosome analysis. The team will define a set of biomarkers that can differentiate between cancer and non-cancer subjects from cells and plasma carrying early signs of human pancreatic cancer. This novel technology will also be applicable for doctors monitoring the development and customising the treatment of a patients tumour.

Pancreatic cancer is difficult to diagnose in the early stages. Early tumour cant be observed during routine physical exams as the pancreas is deep inside the body. Most patients are diagnosed when the cancer has become very large or has spread to other organs. A method to detect pancreatic cancer early on is urgently needed, Dr Zhu said.

My project team aims to develop a blood test to detect pancreatic cancer in the early stages. The team will target exosomes, which are nanosized fragments released by cancer cells. Exosomes are important for communicating messages and transporting materials between cells. Exosomes have been identified as more accurate and promising biomarkers, or biological clues for pancreatic cancer diagnosis, Dr Zhu continued.

We are pleased to award funding to this innovative project, said Michelle Stewart, CEO of the Avner Pancreatic Cancer Foundation. We are encouraged by the high calibre of the research and believe that investment into projects like these will help us to increase survival for people diagnosed with pancreatic cancer.

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World Pancreatic Cancer Day: increasing awareness and inspiring action - UNSW Newsroom

Bradley Nelson : Medical MicroRobotics and NanoMedicine : Teruko Yata Memorial Lecture in Robotics – Video


Bradley Nelson : Medical MicroRobotics and NanoMedicine : Teruko Yata Memorial Lecture in Robotics
Brad Nelson ETH Zrich April 16, 2015 While the futuristic vision of micro and nanorobotics is of intelligent machines that navigate throughout our bodies searching for and destroying disease,...

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Bradley Nelson : Medical MicroRobotics and NanoMedicine : Teruko Yata Memorial Lecture in Robotics - Video

Journal of Nanomedicine & Biotherapeutic Discovery

Nanomedicine is an application of nanotechnology which made its debut with greatly increased possibilities in the field of medicine. Nanomedicine desires to deliver research tools and clinically reformative devices in the near future.

Journal of Nanomedicine & Biotherapeutic Discovery is a scholarly open access journal publishing articles amalgamating broad range of fields of novel nano-medicine field with life sciences. Nanomedicine & Biotherapeutic Discovery is an international, peer-reviewed journal providing an opportunity to researchers and scientist to explore the advanced and latest research developments in the field of nanoscience & nanotechnology.

This is the best academic journal which focuses on the use nanotechnology in diagnostics and therapeutics; pharmacodynamics and pharmacokinetics of nanomedicine, drug delivery systems throughout the biomedical field, biotherapies used in diseases treatment including immune system-targeted therapies, hormonal therapies to the most advanced gene therapy and DNA repair enzyme inhibitor therapy. The journal also includes the nanoparticles, bioavailability, biodistribution of nanomedicines; delivery; imaging; diagnostics; improved therapeutics; innovative biomaterials; regenerative medicine; public health; toxicology; point of care monitoring; nutrition; nanomedical devices; prosthetics; biomimetics and bioinformatics.

The journal includes a wide range of fields in its discipline to create a platform for the authors to make their contribution towards the journal and the editorial office promises a peer review process for the submitted manuscripts for the quality of publishing. Biotherapeutics journals impact factors is mainly calculated based on the number of articles that undergo single blind peer review process by competent Editorial Board so as to ensure excellence, essence of the work and number of citations received for the same published articles.

The journal is using Editorial Manager System for quality peer review process. Editorial Manager is an online manuscript submission, review and tracking systems. Review processing is performed by the editorial board members of Journal of Nanomedicine & Biotherapeutic Discovery or outside experts; at least two independent reviewers approval followed by editor approval is required for acceptance of any citable manuscript. Authors may submit manuscripts and track their progress through the system, hopefully to publication. Reviewers can download manuscripts and submit their opinions to the editor. Editors can manage the whole submission/review/revise/publish process.

Submit manuscript at http://editorialmanager.com/chemistryjournals/ or send as an e-mail attachment to the Editorial Office atnanomedicine@molecularbiologyjournals.com

OMICS International through its Open Access Initiative is committed to make genuine and reliable contributions to the scientific community. OMICS International hosts over 700 leading-edge peer reviewed Open Access Journals and organizes over 1000 International Conferences annually all over the world. OMICS International journals have over 10 million readers and the fame and success of the same can be attributed to the strong editorial board which contains over 50000 eminent personalities that ensure a rapid, quality and quick review process. OMICS International signed agreements with more than 1000 International Societies to make healthcare information Open Access. OMICS International Conferences make the perfect platform for global networking as it brings together renowned speakers and scientists across the globe to a most exciting and memorable scientific event filled with much enlightening interactive sessions, world class exhibitions and poster presentations.

Antibody Drug Conjugates (ADC) is also called as smart bombs which are designed to target the cancer cells without disturbing the healthy cells. Nanotherapeutics, Lipid Nanoparticle siRNA Deliverey, Polymeric Nanoparticles, is used in the development of Antibody Drug Conjugates.

Related Journals of Antibodies Drug Conjugates

NanomedicineJournal, InternationalJournal of Nanomedicine, Journal of Nanomaterials & Molecular Nanotechnology, Artificial Cells,Nanomedicineand Biotechnology, Journal of Nanomedicine and Nanotechnology, European Journal ofNanomedicine, OpenNanomedicineJournal, NatureNanotechnology, Nanotechnology, Journal of Nanoscience and Nanotechnology

Nanomedicine is the application of nanotechnology (the engineering of tiny machines) to the prevention and treatment of disease in the human body. This evolving discipline has the potential to dramatically change medical science. Nanobiotechnology is the application of nanotechnology in biological fields. Nanotechnology is a multidisciplinary field that currently recruits approach, technology and facility available in conventional as well as advanced avenues of engineering, physics, chemistry and biology. Nanobiotechnology is like to be advantageous as: 1. Drug targeting can be achieved by taking advantage of the distinct pathophysiological features of diseased tissues 2. Various nanoproducts can be accumulated at higher concentrations than normal. Related Journals of Nanomedicine and Nanobiotechnology Nanomedicine:Nanotechnology, Biologyand Medicine, Journal of International Journal of Nanomedicine, Journal of Nanomedicine Research, Nanomedicine Journal, Nanomedicine Biotherapeutics Journals, European Journal of Nanomedicine

Nanomedicine is the application of nanotechnology (the engineering of tiny machines) to the prevention and treatment of disease in the human body. This evolving discipline has the potential to dramatically change medical science. Nanomedicine will employ molecular machine systems to address medical problems, and will use molecular knowledge to maintain and improve human health at the molecular scale. Nanomedicine will have extraordinary and far-reaching implications for the medical profession, for the definition of disease, for the diagnosis and treatment of medical conditions including aging, and ultimately for the improvement and extension of natural human biological structure and function. "Nanomedicine is the preservation and improvement of human health using molecular tools and molecular knowledge of the human body." Related Journals of Nanomedicine InternationalJournal of Nanomedicine, EuropeanJournal of Nanomedicine Nanomedicine, NanomedicineNanotechnology Journals, Journal of International Journal of Nanomedicine, Journal of Nanomedicine Research, Nanomedicine Journal, Nanomedicine Biotherapeutics Journals, European Journal of Nanomedicine

Nanotechnology is the branch of technology that deals with dimensions and tolerances of less than 100 nanometres, especially the manipulation of individual atoms and molecules. 'Nanotechnology' refers to the projected ability to construct items from the bottom up, using techniques and tools being developed today to make complete, high performance products. Nanotechnology is helping to considerably improve, even revolutionize, many technology and industry sectors: information technology, energy , environmental science, medicine, homeland security, food safety, and transportation, among many others. Related Journals of Nanotechnology

JournalJournal of Interdisciplinary Nanomedicine, Journalof Nanomedicine Research, International Journal of Green Nanotechnology, Beilstein Journal of Nanotechnology, Journal of Nanotechnology, Science and Applications, American Journal of Nanotechnology, Journal of Nano Research

Biotherapeutics are the essential tools of modern therapies derived from living organisms. The living organisms or the cells are modified such that they produce proteins that treat diseases and help to improve health. These help in preventing serious disease and illnesses, such as rheumatoid arthritis, multiple sclerosis and cancer.

Related Journals of Clinical Biotherapeutics

JSMNanotechnology & Nanomedicine, InternationalJournal of Nanomaterials, Journal of Genetic Syndromes & Gene Therapy, Clinical Therapeutics, Journal of Clinical Pharmacy and Therapeutics, Journal of Nanoscience and Nanotechnology, Nanomedicine:Nanotechnology, Biology, and Medicine, IEEE Transactions onNanotechnology, Journal of BiomedicalNanotechnology, International Journal ofNanotechnology, Beilstein Journal ofNanotechnology

Many approaches have been applied in preclinical and clinical strategies to overcome cancer for example chemosensitizers and nanomedicine. Nanomedicine is used as delivery vehicles that increase the influx of the drugs into the cancer cells. Carbon nanotubes are also a very important in the field of medicine due to its property of drug delivery systems and diagnostics. Experts in the field of nanomedicine say that there are wide ranges of uses of this field in the discovery of spherical nucleic acid nanoparticles, nanoscale engineering behind organs-on-a chip, precision medicine.

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Nanobiotechnology has a great impact on the health issues of humans, as nanoparticles and nanomaterials have provided targeted drug delivery system. Thus, providing human race to fight against diseases such as cancer, diabetes, to combat antimicrobial resistance, and many more. Coming to the implications of this technology has few backdrops such as the nanopollutant which is generated during the manufacturing of nanomaterials, may lead to unwanted hazards to environment by penetrating into plants or animal tissue.

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One particular type of nanoparticle involves the use of liposomes as drug molecule carriers. The diagram on the right shows a standard liposome. It has a phospholipid bilayer separating the interior from the exterior of the cell.

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Nanobiopharmaceutics is the application of nanotechnology into the world of medicine. It is an inter-disciplinary field involving the usage of nanoparticles to deliver biopharmaceutical products into the body. It involves knowledge from nanobiotechnology, biotechnology and biopharmaceutics.

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Nanoemulisers are another form for nanoparticle delivery systems using oil-in-water emulsions done on a nano-scale. This process uses common biocompatible oils such as triglycerides and fatty acids, and combines them with water and surface-coating surfactants.

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Targeted medicine for the treatment of cancer can be obtained with the application of nanotechnology in gene-delivery method. With the use of nanocarriers genes can be administered into the target cells. With the use of Solid lipid nanoparticles as potential tools for gene therapy, in vivo protein expression was observed after intravenous administration.

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Disease diagnosis, target specific drug delivery, molecular imaging is possible with the application of nanotechnology in medicine. Nanoparticles are engineered in an extent that they get attracted to the diseased cells and allows for detection of disease. Nanomedicine is applicable in drug delivery, therapy techniques, diagnostic techniques, anti-microbial techniques, cell repair.

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Nanomedicine is a novel medical application extended in the field of cancer studies. A wide range of nanotechnology tools have provided platform for the early diagnosis, improved imaging and targeted therapies. Cancer nanomedicine has remained progressively applied in areas including nanodrug delivery systems, nanopharmaceuticals, and nanoanalytical contrast reagents in laboratory and animal model research.

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Nanomedicine is playing a key role in the growing part of pharmaceutical research and development (R&D), largely in the form of nanoparticle-based delivery systems for drugs. Researchers are developing advanced drug delivery systems by researching drug conjugates and nanoformulations; polymer, lipid, peptide, and protein nanoparticles; biopharmaceutical protein engineering and chemical conjugation; and self-assembly and processing of nanomedicines.

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Nanoparticles are 1 and 100 nanometers in size particles that are used in medicine which delivers drug specifically to the target cells. These nanoparticles have many advantages over the age old drug delivery systems as nanoparticles are more specific drug delivery systems, reduced toxic effects while continuing therapeutic effects, biocompatible and faster and safe medicine. Some of the major application of these nanoparticles are protein filled nanoparticles, cerium oxide nanoparticles that acts as an antioxidant, chemotherapy drugs attached to nanodiamonds, nickel nanoparticles and a polymer, low cost electrodes for fuel cells.

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Polymeric nanoparticle delivery is the mechanism for the transport of polymer-based nanoparticles across the blood-brain barrier and has been characterized as receptor-mediated endocytosis by the brain capillary endothelial cells.

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Polymeric nanoparticles, self-emulsifying delivery systems, liposomes, microemulsions, micellar solutions and recently solid lipid nanoparticles (SLN) have been exploited as probable possibilities as carriers for oral intestinal lymphatic delivery.

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Immunotherapy has a great significance in the cancer therapy. Nanotechnology-based therapeutic agents and drug carriers are formulated so that they attack only the cancer cells. Nanocarriers using the DNA, RNA, proteins have shown better results in cancer immunotherapy.

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Nanotoxicology is the study of the toxicity of nanomaterials. Because of quantum size effects and large surface area to volume ratio, nanomaterials have unique properties compared with their larger counterparts.

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Journal of Nanomedicine & Biotherapeutic Discovery

Comprehensive Analysis On Nanomedicine Market Based On Types And Application The Bisouv Network – The Bisouv Network

The Nanomedicine market report provides a detailed analysis of the emerging trends, opportunities, and as well as the challenges in the market. This extensive report sheds light on the latest developments, market drivers, and competitive analysis to help the new entrants and emerging players to make crucial decisions.

Besides this, the market research report presents insights on consumer behavior, regulatory policies, and supply & demand scenario to provide a holistic view of the market. The primitive aim of the report is to represent the critical data and figures of the market concisely and layout top winning strategies to aid industry players to leverage their market position.

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The dedicated research team has included Porters Five Point Force analysis to tailor the Nanomedicine Market. They have conducted interviews with industry experts to provide accurate predictions and better insights in a detailed manner. The research report covers the latest advancements that have overhauled the market dynamics while examined the threats which has impacted the overall market.

Key Answers Captured in the Study are

Complete Purchase of Latest Version Global Nanomedicine Market Study with COVID-19 Impact Analysis: https://dataintelo.com/checkout/?reportId=81345

Important Features that are under offering & key highlights of the report:

Detailed overview of Nanomedicine

Changing market dynamics of the industry

In-depth market segmentation by Type, Application, etc.

Historical, current, and projected market size in terms of volume and value

Recent industry trends and developments

Competitive landscape of Nanomedicine

Strategies of key players and product offerings

Potential and niche segments/regions exhibiting promising growth

A neutral perspective towards Nanomedicine performance

Market players information to sustain and enhance their footprint

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Research Objectives

To analyze and forecast the Worldwide Nanomedicine, in terms of value and volume.

Which segment has the potential to gain the highest market share?

To help decision-makers from a new offer perspective and benchmark existing marketing strategy.

Correlate cost structure historical data with key business segments.

Analyze marketing contribution and customer acquisition by up-selling and cross-selling.

Identifying Influencing factors keeping Worldwide Nanomedicine Intense, factored with periodic analysis of CR4 & CR8 concentration ratio & HHI Index.

Important Features that are under offering & key highlights of the report:

1) Does the study cover COVID-19 Impact Analysis and its effect on Growth %?

Yes, the overall industry has seen quite a big impact due to slowdown and shutdown in the production line & supply chain. The study covers a separate qualitative chapter on COVID-19 Impact analysis. Additionally, it also provides before and after the scenario of COVID-19 on sales growth & market size estimation to better analyze the exact scenario of the industry.

2) How companies are selected or profiled in the report?

List of some players that are profiled in the report include:

CombimatrixAblynxAbraxis BioscienceCelgeneMallinckrodtArrowhead ResearchGE HealthcareMerckPfizerNanosphereEpeius BiotechnologiesCytimmune SciencesNanospectra Biosciences

Usually, we follow NAICS Industry standards and validate company profile with product mapping to filter relevant Industry players, furthermore the list is sorted to come up with a sample size of at least 50 to 100 companies having greater topline value to get their segment revenue for market estimation.

** List of companies mentioned may vary in the final report subject to Name Change / Merger etc.

3) Can we add or profiled a new company as per our needs?

Yes, we can add or profile a new company as per client need in the report, provided it is available in our coverage list as mentioned in answer to Question 1 and after feasibility run, final confirmation will be provided by the research team checking the constraints related to the difficulty of survey.

4) Can we narrow the available business segments?

Yes, depending upon the data availability and feasibility check by our Research Analyst, a further breakdown in business segments by end-use application or product type can be provided (If applicable) by Revenue Size or Volume*.

Nanomedicine market segmentation

The Study is segmented by following Product Type:

Quantum dotsNanoparticlesNanoshellsNanotubesNanodevices

Major applications/end-users industry are as follows:

Segmentation encompasses oncologyInfectious diseasesCardiologyOrthopedicsOthers

5) Can a specific country of interest be added? What all regional segmentation covered?

Yes, Country-level splits can be modified in the study as per objectives. Currently, the research report gives special attention and focus on the following regions:

North America [United States, Canada, Mexico], Asia-Pacific [China, India, Japan, South Korea, Australia, Indonesia, Malaysia, Philippines, Thailand, Vietnam], Europe [Germany, France, UK, Italy, Russia, Rest of Europe], South America [Brazil, Argentina, Rest of South America], Middle East & Africa [GCC Countries, Turkey, Egypt, South Africa, Rest of the Middle East & Africa]

** One country of specific interest can be included at no added cost. For inclusion of more regional segment quotes will vary.

Get on the call with our research analyst if you have any particular doubts before buying the report @ https://dataintelo.com/enquiry-before-buying/?reportId=81345

About US:

DATAINTELO has set its benchmark in the market research industry by providing syndicated and customized research report to the clients. The database of the company is updated on a daily basis to prompt the clients with the latest trends and in-depth analysis of the industry.

Our pool of database contains various industry verticals that include: IT & Telecom, Food Beverage, Automotive, Healthcare, Chemicals and Energy, Consumer foods, Food and beverages, and many more. Each and every report goes through the proper research methodology, validated from the professionals and analysts to ensure the eminent quality reports.

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Comprehensive Analysis On Nanomedicine Market Based On Types And Application The Bisouv Network - The Bisouv Network

Quilts for pancreatic cancer patients and research – University of Strathclyde

Chemistry researchers at the University of Strathclyde are aiming to raise awareness of pancreatic cancer with the use of specially-made quilts.

Fellow cancer researchers across the UK are being asked to send diagrams illustrating their work. These will then be used as the patterns for quilts made by skilled crafters.

After the project is concluded, the Strathclyde researchers hope to be able to display the quilts in an exhibition, which may be held online if a physical exhibition is not possible. The quilts will then be donated to local pancreatic cancer patients

The project, titled Quilts4Cancer, is being funded through a grant of 4700 from the Royal Society of Chemistry.

Nearly 9,500 people each year are diagnosed with pancreatic cancer in the UK.

Dr Clare Hoskins, a Reader in Strathclydes Department of Pure and Applied Chemistry, is leading Quilts4Cancer, along with Dr Kirsty Ross, the Departments Outreach Officer. The programme is being launched to coincide with Pancreatic Cancer Awareness Month in November.

Dr Hoskins said: Funds for cancer research have dropped significantly in the pandemic but we aim to raise awareness of chemistry research across the UK towards better therapies for pancreatic cancer, as well as raising awareness of its signs and symptoms.

We chose to have quilts made because its known that chemotherapy patients get cold during their treatment. The therapy has serious side effects but we want to raise awareness of the new technology and compounds coming through; a lot of work is being done on making treatment safer, with fewer side effects.

Were asking for researchers in the chemical sciences to send simple diagrams based on their research, with small summaries of what it is and who is carrying it out. It could show the chemical structures of treatments or technology such as ultrasound equipment.

My design illustrates my research in laser-activated nanomedicine. It shows nanoparticles which have been found to penetrate deep into pancreatic tumour tissue, allowing for drug treatments to reach the site where they are required and help reduce the unpleasant side effects. These nanoparticles act as chaperones for the drug molecules, carrying their cargo past the bodys defence systems and to their target site.

On arrival, a laser beam activates them to release their drugs, making them more effective than conventional chemotherapy. The nanocarriers themselves are relatively simple and cheap to make and they can be easily tailored for different uses and cancer types.

Dr Hoskins and Dr Ross have created a Quilts4Cancer Facebook page. Anyone wishing to participate in the project can contact Dr Hoskins.

The project will hold evening stitching sessions throughout November. Register for the sessions.

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Quilts for pancreatic cancer patients and research - University of Strathclyde

Why Exosomes Are Being Explored as Diagnostic and Therapeutic Tools – Technology Networks

In 1983, two separate research groups reported novel observations regarding small, extracellular vesicles released by maturing red blood cells.1,2 Five years later, the vesicles were named exosomes by Rose Johnstone, an author from one of the original studies.3 On reflection, Johnstone describes her groups early discovery as somewhat accidental, explaining they stumbled upon exosomes when they were looking for an appropriate system to identify a specific transport protein.4 According to Johnstone, reports of the observation were initially met with disbelieving eyes.Now, the initial skepticism has been overcome; instead of being considered an artifact, exosome formation is now accepted as a natural phenomenon. As biologists race to unlock the potential of exosomes, research in the field continues to gain momentum; enter exosomes in the PubMed search box and you will see over 4000 results from 2020 alone (up from 265 results in 2010). In this article, we provide an overview of the biology of exosomes and explore their potential uses as diagnostic and therapeutic tools a market now valued at over $41 million and projected to reach $358.91 million by 2027.

Live reporters like these can reveal unexpected cellular behaviors by allowing real-time visualization of the secretion and interaction of exosomes with cells. Although we know exosomes are important for directional migration, we were surprised by how closely the cells followed the exosome trails as if the exosomes were releasing an attracting factor or pheromone.

For Wafa Al-Jamal, reader in nanomedicine and drug delivery at Queens University Belfast School of Pharmacy, Northern Ireland, UK, exosome mimetics represent a way forward in her mission to develop personalized, effective and safe nanomedicines targeting metastatic prostate cancer. Our vision, says Al-Jamal, is to engineer targeted exosome mimetics from patients' blood cells, so the treatment is customized for each patient. Al-Jamal notes how challenging it has been to deliver effective doses of chemotherapeutics to metastatic lesions especially in bone without causing toxicity to healthy tissues. The approach, described recently in the Journal of Controlled Release, aims to improve drug delivery by targeting drug-loaded exosome mimetics to advanced and metastatic prostate cancer lesions by combining the intrinsic affinity of exosome mimetics with active targeting via prostate-specific membrane antigen (PSMA).29Our approach is based on filtering whole monocyte cells into smaller cell-mimetic vesicles using different pore size membranes, which generates vesicles similar to naturally-secreted extracellular vesicles (e.g., exosomes) but accelerates production and increases yield, explains Al-Jamal. Moreover, our approach aims to prepare targeted vesicles expressing a prostate-targeting ligand on the cells' surface, eliminating the chemical procedures that would otherwise be required to attach the targeting ligand to the vesicles surface.

Exosome mimetics also provide an opportunity for theranostics, i.e., the combination of diagnostic and therapeutic applications to predict therapy outcomes in animal models and patients. Al-Jamal explains how the co-delivery of diagnostics and therapeutics in a single nanocarrier could be achieved: Due to the vesicular nature of exosome mimetics, drugs and imaging agents could be co-loaded into the same vesicles. Alternatively, imaging agents could be conjugated to the vesicles surface.

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Why Exosomes Are Being Explored as Diagnostic and Therapeutic Tools - Technology Networks