Scientists Found a Way to Control How High Mice Got on Cocaine

A team of neuroscientists at the University of Wisconsin claim to have found a way to control how high mice can get on cocaine.

A team of neuroscientists at the University of Wisconsin claim to have found a way to control how high mice can get on a given amount of cocaine.

And don't worry — while that may sound like a particularly frivolous plot concocted by a team of evil scientists, the goal of the research is well-meaning.

The team, led by University of Wisconsin neuroscientist Santiago Cuesta, was investigating how the gut microbiome can influence how mice and humans react to ingesting the drug.

The research, detailed in a new paper published this week in the journal Cell Host & Microbe, sheds light on a vicious feedback loop that could explain cases of substance abuse disorders — and possibly lay the groundwork for future therapeutic treatments.

In a number of experiments on mice, the researchers found that cocaine was linked to the growth of common gut bacteria, which feed on glycine, a chemical that facilitates basic brain functions.

The lower the levels of glycine in the brain, the more the mice reacted to the cocaine, exhibiting abnormal behaviors.

To test the theory, the scientists injected the mice with a genetically modified amino acid which cannot break down glycine. As a result, the behavior of mice returned to normal levels.

In other words, the amino acid could curb cocaine addiction-like behaviors — at least in animal models.

"The gut bacteria are consuming all of the glycine and the levels are decreasing systemically and in the brain," said Vanessa Sperandio, senior author, and microbiologist from the University of Wisconsin, in a statement. "It seems changing glycine overall is impacting the glutamatergic synapses that make the animals more prone to develop addiction."

It's an unorthodox approach to treating addiction, but could be intriguing — if it works in people, that is.

"Usually, for neuroscience behaviors, people are not thinking about controlling the microbiota, and microbiota studies usually don't measure behaviors, but here we show they’re connected," Cuesta added. "Our microbiome can actually modulate psychiatric or brain-related behaviors."

In short, their research could lead to new ways of treating various psychiatric disorders such as substance use by adjusting the gut microbiome and not making changes to the brain chemistry.

"I think the bridging of these communities is what's going to move the field forward, advancing beyond correlations towards causations for the different types of psychiatric disorders," Sperandio argued.

READ MORE: How gut bacteria influence the effects of cocaine in mice [Cell Press]

More on addiction: Study: Magic Mushrooms Helped 83% of People Cut Excessive Drinking

The post Scientists Found a Way to Control How High Mice Got on Cocaine appeared first on Futurism.

Follow this link:

Scientists Found a Way to Control How High Mice Got on Cocaine

Micro and Nano Engineering – Journal – Elsevier

Micro and Nano Engineering (MNE) is an open access, multidisciplinary journal which crosses boundaries from nano to micro to bio, and from science to technologies. The journal focuses on micro-/nano engineering, fabrication and integration of functional nanostructures and surfaces towards intelligent nanomanufacturing; devices and bio-microsystems for medicine, life sciences, chemistry, environmental sciences, and agrofood; and devices and microsystems for physical applications.

MNE places an emphasis on the "method to make and characterize" the structure, functional surface, device, or system and provide a demonstration of its application. The main publishing criteria are novelty, potential usefulness and impact.

The Editors welcome communications of ground-breaking new results, original research papers, review articles from experts in the field, and news and opinion papers.

MNE scope primarily addresses the following three main topics:

1.Micro-/Nano-engineering, fabrication and integration of functional micro-nanostructures and surfaces towards intelligent micro-nanomanufacturing

This topic aims at presenting novel approaches or improvements in fabrication of nanostructures, surfaces or nanomaterials in 0D, 1D, 2D, or 3D including, as well as demonstrating (multi)functionality and other properties of the nanostructures or surfaces. Topics here include but are not limited to:

Contributions to this topic should address biological, bioanalytical, analytical, food and agrofood, health and medicine monitoring and safety problems and show how micro/nano engineering can provide the appropriate solution, starting from 3D micro-nano structures, functional surfaces, microfluidics, and scaffolds, all the way to nanobiosensors, BioMEMS, lab on a chip and health & medicine or environmental monitoring. Targeted areas can be:

This topic encompasses the use of micro/nano fabrication methods for building up new solutions for application areas in Physical disciplines such as Nanoelectronics, Photonics, Plasmonics, Physical Sensing and Energy Harvesting. The solutions can be in the form of devices or complete systems. Contributions should not only describe the fabrication procedure, but should also include demonstration of the application and integration steps. This topic includes but is not limited to:

View post:

Micro and Nano Engineering - Journal - Elsevier

People | Centre for Nano Science and Engineering (CeNSE), IISc

If you are a recent engineering/Physics/chemistry graduate (B.E/B.Tech or M.E/M.Tech, M.Sc) and looking for an opportunity to work in an advanced technology then look no further than National nanofabrication Centre (NNfC) at Indian Institute of Science, Bangalore

NNfC is an equal opportunity national facility and part of Centre for nanoscience and engineering (CeNSE), situated in the beautiful campus of Indian Institute of Science, Bangalore. Equipped with state of the art nanofabrication capabilities, NNfC offers an excellent platform for advanced research and fabrication facility.

What does it mean to work in NNfC?

Career development and growth opportunities

NNfC gives you a platform to freely interact with researchers and improve your personal skills in science and technology. We even encourage entrepreneurship.

How to be a part of NNfC?

NNFC has various openings for process engineers. Selection will be through a mandatory internship process (8 weeks). Interns are selected through an interview process and Candidates finishing Internship will appear for job interview at NNfC. Successful candidates will be considered for the following positions. Facility Technologist (FT) /Senior Facility Technologists (SFT) with a starting salary from Rs.25,000 to Rs.75,000 /month.

Minimum qualifications for internship: Applicants should have COMPLETED B.E/B.Tech/M.E/M.Tech/M.Sc (Electronics, ECE, Physics or related subjects)Stipend*: Rs. 25000/month as an internship stipend upon completion of the program.

Interested candidates, please send your resumes to nnfc.cense@iisc.ac.in, on or before 15th Apr 2022.

*No TA/DA will be provided for written test/interview attendees. No accommodation will be provided during internship.

See the rest here:

People | Centre for Nano Science and Engineering (CeNSE), IISc

Arduino Nano Library for Proteus – The Engineering Projects

Update: We have created a new version of this library, which you can check here: Arduino Nano Library for Proteus V2.0.

Hello friends, hope you all are fine and having fun with your lives. In today's post I am gonna share a new Arduino Nano Library for Proteus. Arduino Nano is also a microcontroller board just like Arduino UNO but the advantage of Arduino Nano over Arduino UNO is its small size. Arduino Nano is quite small in size and hence can be used in such projects where we need to use smaller pcbs. For example, I have once worked on a project in which I need to design a testing cricket bat. In that project, I have used IMU along with Arduino Nano and I have placed the complete kit over to bat. So,as I need to place the electronic kit over to bat so it has to be quite small, that's why I have used Arduino Nano instead of Arduino UNO board. So, now I hope you got the idea where to use Arduino Nano instead of Arduino UNO.

Now, coming to Proteus software,in Proteus we don't have the default board for Arduino Nano so that's why I have designed this Arduino Nano Library for Proteus, using which you can quite easily use the Arduino Nano board in Proteus and can test your code quite easily. I have already posted the Arduino UNO Library for Proteus and has also posted Arduino Mega 2560 Library for Proteus. So, now today I am posting the third Arduino Library for Proteus. Hope you are gonna like it as well.

In the next tutorials, I am also gonna share more Arduino Libraries for Proteus. I am working on Arduino Mini and Arduino Pro Mini as well. So, I will post their libraries too once I get them completed. I am also planning on designing the Sim900D Library for Proteus but till now I haven't started it. I am planning to post a complete Arduino Library at the end in which you just need to install one library and all the Arduino boards will come in Proteus. Anyways, let's get started with the Arduino Nano Library for Proteus.

I have added all the Arduino boards in a single library. This library contains six Arduino boards which are Arduino UNO, Arduino Mega 2560, Arduino Mega 1280, Arduino Nano, Arduino Mini and Arduino Pro Mini. You can download this complete Arduino Library by checking Arduino Library for Proteus.

See the original post:

Arduino Nano Library for Proteus - The Engineering Projects

Forge Nano and Anovion Partner to Help Propel US Battery Tech and Strengthen Domestic Supply Chain – GlobeNewswire

DENVER, June 28, 2022 (GLOBE NEWSWIRE) -- Anovion and Forge Nano Inc. are working together to bring cutting-edge battery anode materials technology to the U.S. market. The companies will useForge Nano'sproprietary technology,withAnovion's combined 140+ years of synthetic graphite manufacturing and experience, to secure domestic energy initiatives and alleviate supply chain issues.

Forge Nano's surface engineering platform technology will be used to apply specialized coatings to Anovion's synthetic graphite battery materials. The Parties are co-developing market-leading material for battery and energy storage products in the U.S.

The two companies are building upon an already successful partnership hot on the tail of their recently launchedSpace Batteries, a project designed to protect and improve the performance of high-tech batteries sent into orbit. These cutting-edge batteries perform reliably in the frigid outer reaches of space and have demonstrated the ability to cycle over 1,700 times with 0% loss of capacity.

This partnership aims to make security and supply chain issues for batteries a thing of the past. The companies together will create next gen, U.S.-made batteries with raw materials sourced in North America.

Anovion is developing its first large-scale production facility which will support the supply of synthetic graphite anode product in the range of 50,000-70,000 tons per year to large format battery producers supplying mass markets such as EVs.

"Until now, foreign producers have controlled the global supply of anode material. In our current operation, Anovion has made major strides in R&D and process development, along with the commercialization of existing products," said Eric Stopka, Chief Executive Officer of Anovion. "This exciting partnership with industry leader, Forge Nano, helps us supply the market with another critical product line. We're proud to be joining forces to help solve the critical need for a domestic supply of battery materials."

James Trevey, Forge Nano's Chief Technology Officer, adds:"Forge Nano is a very active participant towardenabling energy security for the U.S. throughpartnerships with material suppliers. This partnership with Anovion is exemplary in paving the path for premium-performance, low-cost materials to be made in the U.S., using new technology to leapfrog over incumbent technologies, creating a better product, and just as important, a better process for graphite production which reduces the environmental impact of manufacturing."

What do these coatings do for batteries?

Forge Nano's proprietary coatings for battery materials stabilize the surfaces at the atomic level. These coatings prevent excessive wear and damage to the batteries by preventing unwanted reactions between the battery's internal components. Batteries treated with the ALD process last longer, charge faster, and dissipate heat more effectively.

About Forge Nano

Forge Nano is a global leader in surface engineering and precision nano-coating technology, using Atomic Layer Deposition (ALD). The Company's proprietary technology and manufacturing processes make atom-thick coatings fast, affordable, and commercially viable for a wide range of materials, applications, and industries. Forge Nano's suite of proprietary equipment and services covers the full spectrum from lab-scale tools to commercial-scale manufacturing.

About Anovion

Headquartered in Chicago, IL, Anovion brings over 140 years of experience in the production of synthetic graphite materials. As a leader in synthetic graphite lithium-ion anode materials innovation and manufacturing, Anovion has the largest domestic commercial production today. Their qualified products are in commercial production with customers in key North American markets such as commercial electric vehicles, aerospace, and defense, and are undergoing qualification testing with leading automotive electric vehicle OEMs and suppliers, among many others. Anovion plans for a capacity expansion targeting up to 150,000 tons per annum of finished product by 2030. For more information, visit http://www.anovion-anode.com.

CONTACT

Michael Talarico

Marketing Director

mtalarico@forgenano.com

(720) 259-8579

Related Images

Image 1: Forge Nano 40Ah Battery

Forge Nano EV battery for automotive applications.

This content was issued through the press release distribution service at Newswire.com.

View original post here:

Forge Nano and Anovion Partner to Help Propel US Battery Tech and Strengthen Domestic Supply Chain - GlobeNewswire

Nanotechnology Market 2022 Detailed Analysis Of Current Industry Demand with Forecasts Growth by 2028 Designer Women – Designer Women

Nanotechnology Market research report brings to light key market dynamics of sector. The report gives correct insights on the current market scenario and future prospects of the industry. It neatly describes historic data, present market trends, market environment, technological improvements, upcoming technologies and the technical progress in the related industry. Major market players, major collaborations, mergers & acquisitions are reviewed comprehensively in the market report. Moreover, this market study also analyzes the market status, market share, growth rate, future trends, market drivers, opportunities and challenges, sales channels, distributors and Porters Five Forces Analysis. Market risks and entry barriers makes industry attentive and help deciding further moves.

Moreover, two more major success factors of the credible market report can be mentioned here which are market share analysis and key trend analysis. The research methodology employed in the report by DBMR research team is data triangulation which includes data mining, studying the impact of data variables on the market, and primary validation by industry experts. Being an outstanding and a comprehensive in nature, this report focuses on primary and secondary market drivers, market share, leading segments and geographical analysis. With the nice mixture of integrated approaches and latest technology, best results are achieved in the form of this market research report.

The nanotechnology market is expected to gain market growth in the forecast period of 2021 to 2028. Data Bridge Market Research analyses the market to grow at a CAGR of 16.45% in the above-mentioned forecast period. High technological advancements and applications of nanotechnology drives the nanotechnology market.

Download Exclusive Sample Report (350 Pages PDF with All Related Graphs & Charts) @ https://www.databridgemarketresearch.com/request-a-sample/?dbmr=global-nanotechnology-market&pm

Major Player :-

The major players covered in the nanotechnology market report are Honeywell International Inc, DuPont, 3M, Sioen Industries, Kimberly-Clark, Glen Raven, Inc, Derekduck Industries Corp, ANSELL LTD, Lakeland Inc, Advanced Electron Beams (AEB), ACS Material, Abraxis, Inc., Bruker, Agilent, Nanosurf AG, Nanoscience Instruments, Hysitron, Inc and Malvern Panalytical Ltd among other domestic and global players.

Competitive Landscape and Nanotechnology Market Share Analysis

The nanotechnology market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies focus related to nanotechnology market.

Nanoscience is defined as the study of extremely small things. The development of nanotechnology is being growing in many fields, as it has numerous applications, such as in chemistry, biology, physics, materials science and engineering. Nanotechnology deals with the use of nanoparticle of size of 1 to 100 nm to be used in all major field of medical.

Rise in theresearch and developmentactivities of major players in the field of nanotechnology is the vital factor escalating the market growth, also rise in the demand of nanotechnology based devices or equipment, rise in the adoption of nanotechnology in medical diagnosis and rise in the emerging technological advancements in nanotech devices are the major factors among others driving the nanotechnology market. Moreover, rise in thegovernmentfunding initiatives and increasing technological advancements and modernization in the healthcare devices will further create new opportunities for nanotechnology market in the forecasted period of 2021-2028.

However, high cost of nano based devices and lack of skilled professionals are the major factors among others which will obstruct the market growth, and will further challenge the growth of nanotechnology market in the forecast period mentioned above.

The nanotechnology market report provides details of new recent developments, trade regulations, import export analysis, production analysis, value chain optimization, market share, impact of domestic and localised market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market.

Nanotechnology Market Scope and Market Size

The nanotechnology market is segmented on the basis of type, application and end-user industry. The growth amongst these segments will help you analyse meagre growth segments in the industries, and provide the users with valuable market overview and market insights to help them in making strategic decisions for identification of core market applications.

Nanotechnology Market Country Level Analysis

The nanotechnology market is analysed and market size insights and trends are provided by country, type, application and end-user industry as referenced above.

The countries covered in the nanotechnology market report are U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.

North America dominates the nanotechnology market due to rise in the presence of technologically advanced healthcare infrastructure, increase in the patient and healthcare practitioners and rise in the presence of numerous nano-technology in this region.

The country section of the nanotechnology market report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points such as consumption volumes, production sites and volumes, import export analysis, price trend analysis, cost of raw materials, down-stream and upstream value chain analysis are some of the major pointers used to forecast the market scenario for individual countries. Also, presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.

For More Insights Get FREE Detailed TOC @ https://www.databridgemarketresearch.com/toc/?dbmr=global-nanotechnology-market&pm

Healthcare Infrastructure growth Installed base and New Technology Penetration

The nanotechnology market also provides you with detailed market analysis for every country growth in healthcare expenditure for capital equipments, installed base of different kind of products for nanotechnology market, impact of technology using life line curves and changes in healthcare regulatory scenarios and their impact on the nanotechnology market. The data is available for historic period 2010 to 2019.

Read More @ https://www.databridgemarketresearch.com/reports/global-nanotechnology-market?pm

About Data Bridge Market Research:

An absolute way to forecast what future holds is to comprehend the trend today!Data Bridge set forth itself as an unconventional and neoteric Market research and consulting firm with unparalleled level of resilience and integrated approaches. We are determined to unearth the best market opportunities and foster efficient information for your business to thrive in the market. Data Bridge endeavors to provide appropriate solutions to the complex business challenges and initiates an effortless decision-making process.

Contact:

Data Bridge Market Research

US: +1 888 387 2818

UK: +44 208 089 1725

Hong Kong: +852 8192 7475

Corporatesales@databridgemarketresearch.com

See the article here:

Nanotechnology Market 2022 Detailed Analysis Of Current Industry Demand with Forecasts Growth by 2028 Designer Women - Designer Women

Why is the Weebit Nano share price charging 5% higher today? – The Motley Fool Australia

Image source: Getty Images

In a sea of red across the ASX, theWeebit Nano Ltd(ASX: WBT) share price is powering ahead today.

This comes after the semiconductor company announced an exciting development.

At the time of writing, Weebit Nano shares are up 5.12% to $2.26.

In contrast, theS&P/ASX 200 Index(ASX: XJO) is down 1.23% to 6,680.6 points following heavy falls on Wall Street overnight.

Lets take a look at why shares in the next generation computer memory technology are defying the ASX sell-off today.

Following the companys latest announcement, investors are fighting to get a hold of Weebit Nano shares.

According to theupdate, the company advised it has released its demonstration chips to the SkyWaters production fab.

Based in the United States, SkyWater is a pure-play silicon foundry that specialises in advanced engineering and manufacturing services.

The demonstration chips are embedded with Weebit Nanos Resistive Random-Access Memory (ReRAM) technology.

ReRAM is over 1000 times faster and uses 1000 times less power than traditional storage options like flash.

Notably, this is the first time the company transferred its ReRAM technology to an outside party for testing and prototyping.

Weebit Nano stated that this marks a significant milestone towards commercialisation into the semiconductor market.

Due to the technologys ultra-low power consumption and ability to integrate easily, this has sparked interest among SkyWaters customers.

In particular, this would be well suited for analogue, power management, automotive, Internet of Things (IoT), and medical applications.

Weebit Nano CEO, Coby Hanoch commented:

Weve developed a close and efficient partnership with SkyWater, enabling us to meet our milestones, and bringing us ever closer to volume production. This successful tape- out concludes the technology transfer to SkyWaters US production fab, and once the chips are back from the fab, we will proceed with technology qualification.

Were in discussions with early-adopter customers looking to leverage our faster, more efficient memory technology to increase their competitiveness in the market.

A volatile 2022 has led the Weebit Nano share price to sink 20% for the period.

However, when looking at the past 12 months, its shares are up 30%.

Based on todays price, Weebit Nano presides amarket capitalisationof approximately $380.79 million.

More here:

Why is the Weebit Nano share price charging 5% higher today? - The Motley Fool Australia

Stanford engineers’ optical concentrator could help solar arrays capture more light even on a cloudy day without tracking the Sun – EurekAlert

image:Nina Vaidya measuring the experimental performance of optical concentrators under a solar simulator that acts as an artificial sun. view more

Credit: Courtesy Nina Vaidya

Even with the impressive and continuous advances in solar technologies, the question remains: How can we efficiently collect energy from sunlight coming from varying angles from sunrise to sunset?

Solar panels work best when sunlight hits them directly. To capture as much energy as possible, many solar arrays actively rotate towards the sun as it moves across the sky. This makes them more efficient, but also more expensive and complicated to build and maintain than a stationary system.

These active systems may not be necessary in the future. At Stanford University, engineering researcherNina Vaidyadesigned an elegant device that can efficiently gather and concentrate light that falls on it, regardless of the angle and frequency of that light. Apaperdescribing the systems performance, and the theory behind it, is the cover story in the July issue ofMicrosystems & Nanoengineering,authored by Vaidya and her doctoral advisorOlav Solgaard, professor of electrical engineering at Stanford.

Its a completely passive system it doesnt need energy to track the source or have any moving parts, said Vaidya, who is now an assistant professor at the University of Southampton, UK. Without optical focus that moves positions or need for tracking systems, concentrating light becomes much simpler.

The device, which the researchers are calling AGILE an acronym for Axially Graded Index Lens is deceptively straightforward. It looks like an upside-down pyramid with the point lopped off. Light enters the square, tile-able top from any number of angles and is funneled down to create a brighter spot at the output.

In their prototypes, the researchers were able to capture over 90% of the light that hit the surface and create spots at the output that were three times brighter than the incoming light. Installed in a layer on top of solar cells, they could make solar arrays more efficient and capture not only direct sunlight, but also diffuse light that has been scattered by the Earths atmosphere, weather, and seasons.

A top layer of AGILE could replace the existing encapsulation that protects solar arrays, remove the need to track the sun, create space for cooling and circuitry to run between the narrowing pyramids of the individual devices, and, most importantly, reduce the amount of solar cell area needed to produce energy and hence reduce the costs. And the uses arent limited to terrestrial solar installations: if applied to solar arrays being sent into space, an AGILE layer could both concentrate light without solar tracking and provide necessary protection from radiation.Envisioning the perfect AGILE

The basic premise behind AGILE is similar to using a magnifying glass to burn spots on leaves on a sunny day. The lens of the magnifying glass focuses the suns rays into a smaller, brighter point. But with a magnifying glass, the focal point moves as the sun does. Vaidya and Solgaard found a way to create a lens that takes rays from all angles but always concentrates light at the same output position.

We wanted to create something that takes in light and concentrates it at the same position, even as the source changes direction, said Vaidya. We dont want to have to keep moving our detector or solar cell or moving the system to face the source.

Vaidya and Solgaard determined that, theoretically, it would be possible to collect and concentrate scattered light using an engineered material that smoothly increased in refractive index a property that describes how quickly light travels through a material causing the light to bend and curve towards a focal point. At the surface of the material, the light would hardly bend at all. By the time it reached the other side, it would be almost vertical and focused.

The best solutions are often the simplest of ideas. An ideal AGILE has, at the very front of it, the same refractive index as the air and it gradually gets higher the light bends in a perfectly smooth curve, said Solgaard. But in a practical situation, youre not going to have that ideal AGILE.

For the prototypes, the researchers layered together different glasses and polymers that bend light to different degrees, creating whats known as a graded index material. The layers change the lights direction in steps instead of a smooth curve, which the researchers found to be a good approximation of the ideal AGILE. The sides of the prototypes are mirrored, so any light going in the wrong direction is bounced back towards the output.

One of the biggest challenges was finding and creating the right materials, Vaidya says. The material layers in the AGILE prototype let a broad spectrum of light, from near-ultraviolet to infrared, pass through it and bend that light increasingly towards the output with a wide range of refractive indices, which is not seen in nature or the present optics industry. These materials used also had to be compatible with each other if one glass expanded in response to heat at a different rate than another, the whole device could crack and robust enough to be machined into shape and remain durable.

Its one of these moonshot engineering adventures, going right from theory to real prototypes, said Vaidya. There are a lot of theory papers and great ideas out there, but its hard to turn them into reality with real designs and real materials pushing the boundaries of what was deemed impossible before.

After exploring many materials, creating new fabrication techniques, and testing multiple prototypes, the researchers landed on AGILE designs that performed well using commercially available polymers and glasses. AGILE has also been fabricated using 3D printing in the authors priorworkthat created lightweight and design-flexible polymeric lenses with nanometer-scale surface roughness. Vaidya hopes the AGILE designs will be able to be put to use in the solar industry and other areas as well. AGILE has several potential applications in areas like laser coupling, display technologies, and illumination such as solid-state lighting, which is more energy efficient than older methods of lighting.

Using our efforts and knowledge to make meaningful engineering systems has been my driving force, even when some trials were not working out, said Vaidya. To be able to use these new materials, these new fabrication techniques, and this new AGILE concept to create better solar concentrators has been very rewarding. Abundant and affordable clean energy is a vital part of addressing the urgent climate and sustainability challenges, and we need to catalyze engineering solutions to make that a reality.

Solgaard is the director of the Edward L. Ginzton Laboratory; a member ofStanford Bio-X, theStanford Cancer Institute, and theWu Tsai Neurosciences Institute; and an affiliate of thePrecourt Institute for Energyand theStanford Woods Institute for the Environment.

This work was funded by the Global Climate and Energy Project and the Diversifying Academia, Recruiting Excellence doctoral fellowship program. Acknowledgments to Thomas E. Carver (Flexible Cleanroom) and Tim Brand (Ginzton Crystal Shop) for fabrication support, andReinhold Dauskardt, professor of materials science and engineering, for advice on materials science.Thanks to Xuan Wu for the AGILE video andAlan Truongfor helpwith the graphics images.

To read stories about Stanford science, subscribe to the biweeklyStanford Science Digest.

Microsystems & Nanoengineering

Immersion graded index optics: theory, design, and prototypes

27-Jun-2022

See the original post:

Stanford engineers' optical concentrator could help solar arrays capture more light even on a cloudy day without tracking the Sun - EurekAlert

Determining Ways to Combine the Power Conversion and Storage Capacity Needs of Solar Energy Into One Device – AZoCleantech

Researchers are attempting to find solutions to recurring issues with clean energy, such as solar energy storage, as the climate crisis continues to worsen.

Solar energy is considered to be one of the best renewable resources. However, it has difficulties that stop it from being extensively adopted and substituting traditional energy sources. Since solar energy has been variable across the day and throughout the year, it is essential to have a strong storage system.

At present, solar is transformed into electricity in solar cells, which lack the potential to store the energy long-term, and isolated battery storage systems that are costly and inconvenient. For this issue to be resolved, scientists are trying to determine methods to integrate the storage capacity and power conversion requirements of solar energy into a single device.

Earlier attempts made to streamline the conversion of solar energy and storage put two various components collectively into a complex device architecture, which was eventually heavy, costly, and inefficient. However, considerable progress has been made in integrating such elements into a single device, which shares elements and considerably reduces the issues of earlier designs.

The study was published in the journal Nano Research Energy on May 26th, 2022.

The amount of received solar energy on the Earths surface is up to 100,000 terawatt-hours, which completely meets the demand of the annual global energy consumption of 16 terawatts.

Hairong Xue, Study Author and Assistant Professor, National Institute for Materials Science

Xue continued, However, like wind power, solar energy is intermittent due to fluctuations in isolation. To balance supply and demand, converted solar energy needs to be stored in other energy storage devices.

Therefore, it is imperative to incorporate suitable energy storage technologies into solar cells, enabling effective solar energy utilization and delivering the produced electricity when needed, added Xue.

The paper explains advances in utilizing six various kinds of photo-enhanced rechargeable metal batteries: lithium-sulfur, lithium-ion, zinc-ion, zinc-iodine, lithium-iodine, zinc-oxygen, lithium-oxygen, and lithium-carbon dioxide batteries.

The authors describe the benefits and drawbacks of every kind of battery and how it could be employed for solar-to-electricity power conversion and storage. For example, rechargeable lithium-ion batteries, utilized in several modern electronic devices such as phones, electric vehicles, and laptops are effective. However, it would be hard to scale for solar energy use due to their complex structure.

Scientists indicate that this technology is still in its initial stage and there is still additional research to be performed. Moving forward, they believe the next steps to enhancing the storage of solar energy are by utilizing photo-enhanced rechargeable metal batteries.

It is necessary to explore more suitable electrode materials and optimize the device structure of the batteries. For practical applications, stability and safety issues must be addressed and improved.

Hairong Xue, Study Author and Assistant Professor, National Institute for Materials Science

Xue continued, Although the development of photo-enhanced rechargeable metal batteries is quite fast-based, most of the studies remain in an early stage of laboratory test.

By addressing some critical challenges involving working mechanism, electrode materials, and battery structure design, the goal is to demonstrate viable uses of photo-enhanced rechargeable batteries in electronic and optoelectronic devices, remarked Xue.

Furthermore, the scientists hope to explore how this technology can be employed in other kinds of storage systems and energy conversion.

The additional contributors to the study include Hao Gong of the Department of Chemistry and Materials Science at Nanjing Forestry University; Yusuke Yamauchi of the School of Chemical Engineering & Australian Institute for Bioengineering and Nanotechnology at The University of Queensland; and Takayoshi Sasaki and Renzhi Ma at the International Center for Materials Nanoarchitectonics at the National Institute for Materials Science.

This study was financially supported by the Natural Science Foundation of Jiangsu Province, the China Postdoctoral Science Foundation, Jiangsu Key Laboratory of Electrochemical Energy-Storage Technologies, and the JST-ERATO Yamauchi Materials Space-Tectonics Project.

Hue, H., et al. (2022) Photo-enhanced rechargeable high-energy-density metal batteries for solar energy conversion and storage. Nano Research Energy. doi.org/10.26599/NRE.2022.9120007.

Source: http://www.tup.tsinghua.edu.cn/en/index.html

Read the original post:

Determining Ways to Combine the Power Conversion and Storage Capacity Needs of Solar Energy Into One Device - AZoCleantech

New method based on smart materials for experimenting with cells – Nanowerk

Jun 28, 2022(Nanowerk News) Scientists from 4D-BIOMAP, an ERC research project at the Universidad Carlos III de Madrid (UC3M), have developed a new experimental method, based on magneto-active polymers, to study cellular behaviour.These compounds, which consist of a polymeric matrix (e.g., an elastomer) containing magnetic particles (e.g., iron), mechanically react by changing their shape and stiffness. This system could be used to study complex scenarios (such as brain trauma, wound healing, etc.) or to influence cellular responses, guiding their functions.The top image shows the forces generated by an external magnetic field on particles embedded in the material. These interactions are simulated by a computational model that is able to guide the manufacturing and experimental process (middle image). Finally, the generated forces are transmitted to the cells cultured on the smart material (bottom image). This action on the cells will lead to changes or activation of their biological functions, such as proliferation, migration or orientation, among others. (Image: UC3M)We have managed to reproduce the local deformations that occur in the brain when it is subjected to an impact. This would make it possible to replicate these cases in the laboratory, analysing what happens to the cells and how they are damaged in real time. Furthermore, we have validated the system by demonstrating its capacity to transmit forces to the cells and act on them, explains the researcher in charge of 4D-BIOMAP, Daniel Garca Gonzlez, from the UC3M Continuum Mechanics and Structural Analysis Department.The idea of this project is to be able to carry out studies replicating complex biological processes through a new virtually assisted experimental system, which allows non-invasive and real-time control of the mechanical environment. Biological cells and tissues are continuously subjected to mechanical stress from their surrounding substrate, so analysing and controlling the forces that influence their behaviour would be a milestone for the mechanobiology community.The system proposed by 4D-BIOMAP is based on the use of extremely soft magneto-active polymers that mimic the stiffness of biological materials. Thanks to their qualities, magneto-active materials allow researchers to carry out unrestricted monitoring of biological substrates, as the applied mechanical changes during experimentation can be reversible.Supported by the computational model, we have used all this basic science to design a smart actuation system which, coupled to a microscope developed within the ERC, allows us to visualise the cellular response in situ. In this way, we have consolidated a comprehensive framework to stimulate cellular systems with magneto-active smart materials, says Daniel Garca Gonzlez. This proposed framework paves the way to understanding the complex mechanobiological processes that occur during dynamic deformation states, such as traumatic brain injury, pathological skin scarring or fibrotic remodelling of the heart during a myocardial infarction, for example.Researchers from the University of the West of England (UWE) in Bristol, Imperial College London and the Instituto de Investigacion Sanitaria Gregorio Maraon de Madrid (Gregorio Maranon Health Research Institute in Madrid) have participated in the scientific paper describing these advances, recently published in the journal Applied Materials Today ("Magneto-mechanical system to reproduce and quantify complex strain patterns in biological materials"). Within UC3M, lecturers Miguel ngel Moreno, Jorge Gonzlez, Clara Gomez, Maria Luisa Lpez and ngel Arias from the Continuum Mechanics and Structural Analysis Department, as well as Arrate Muoz and Diego Velasco from the Bioengineering and Aerospace Engineering Department are participating.

Read the rest here:

New method based on smart materials for experimenting with cells - Nanowerk

Aalto University scoops 18M in Academy of Finland research funding – Science Business

The Academy of Finland funding brings six new Academy Research Fellows, 14 Postdoctoral Researchers and 23 Academy Projects to Aalto University. The funded projects strengthen several of Aalto University's research areas, and quantum physics as well as marine and arctic technology were particularly successful

The funding granted to Aalto University by the Academy of Finland from the September 2021 call will boost the universitys research with a total of EUR 17.6 million.

Aalto University is involved in 20 new academy projects. Part of these are consortium projects, and the total number of funded Aalto subprojects is 23. The funding allocated to the academy projects totals approximately EUR 10.1 million, and they include a wide range of research projects in the fields of science and technology, biosciences, health and the environment.

In addition, six new academy research fellows and 14 postdoctoral researchers will begin in Aalto in early September. The total funding granted to Aalto University for the tasks of academy research fellows and postdoctoral researchers is EUR 7.3 million.

The Academy of Finland provides us yearly with the largest amount of competitive funding. We are delighted and proud of our researchers and professors who received grants from the September 2021 call. The funded academy projects and individual academy grants covered several areas of strength of Aalto Universitys research. For instance, this year, several academy research fellows and academy projects were granted in quantum physics. This research area has recently received a lot of positive visibility, and for good reasons. A delightful surprise was that a relatively small area of research, marine and arctic technology, received as many as three Academy projects, says Vice President for ResearchOssi Naukkarinen.

The funding granted to Aalto University by the Academy of Finland from the September 2021 call will boost the universitys research with a total of EUR 17.6 million.

Aalto University is involved in 20 new academy projects. Part of these are consortium projects, and the total number of funded Aalto subprojects is 23. The funding allocated to the academy projects totals approximately EUR 10.1 million, and they include a wide range of research projects in the fields of science and technology, biosciences, health and the environment.

In addition, six new academy research fellows and 14 postdoctoral researchers will begin in Aalto in early September. The total funding granted to Aalto University for the tasks of academy research fellows and postdoctoral researchers is EUR 7.3 million.

The Academy of Finland provides us yearly with the largest amount of competitive funding. We are delighted and proud of our researchers and professors who received grants from the September 2021 call. The funded academy projects and individual academy grants covered several areas of strength of Aalto Universitys research. For instance, this year, several academy research fellows and academy projects were granted in quantum physics. This research area has recently received a lot of positive visibility, and for good reasons. A delightful surprise was that a relatively small area of research, marine and arctic technology, received as many as three Academy projects, says Vice President for ResearchOssi Naukkarinen.

Congratulations to all!

Academy Projects 1.9.202231.8.2026

Babbar, Rohit, Dept. of Computer ScienceScalable and Robust Representation Learning in Large Output Spaces

Fagerholm, Fabian, Dept. of Computer ScienceNaturalistic decision-making in Continuous Experimentation

Foster, Adam, Dept. of Applied PhysicsAutomated discovery atomic force microscopy

Hollanti, Camilla, Dept. of Mathematics and Systems AnalysisNumber-theoretic well-rounded lattices

Elucidation of the structural development during cellulose carbonization for advanced carbon materials (CelCarbo) (consortium)Hummel, Michael, Dept. of Bioproducts and Biosystems, AaltoVaari, Jukka, VTT Ltd

New frontiers in Bayesian optimal design for applied inverse problems (BODAIP) (consortium)Hyvnen, Nuutti, Dept. of Mathematics and Systems Analysis, AaltoHelin, Tapio, LUT University

XAI-based software-defined energy networks via packetized management for fossil fuel-free next-generation of industrial cyber-physical systems (X-SDEN) (konsortio)Jung, Alex, Dept. of Computer Science, AaltoJuliano Nardelli, Pedro, LUT University

Ionosphere-thermosphere response to Space Weather Events (INTERSECT) (consortium)Kallio, Esa, Dept. of Electronics and Nanoengineering, AaltoAikio, Anita, University of OuluKauristie, Kirsti, Finnish Meteorological Institute

Li, Yongdan, Dept. of Chemical and Metallurgical EngineeringResearch on high-performance composite membrane in non-aqueous redox flow battery

Better Health at Home Optimized Human-Centered Care of Predialysis and Home Dialysis Patients (BOC) (consortium)Lillrank, Paul, Dept. of Industrial Engineering and Management, AaltoViitanen, Johanna, Dept. of Computer Science, AaltoEkstrand, Agneta, Helsinki University Central HospitalKnittle, Keegan, University of HelsinkiSmolander, Maria, VTT Ltd

Musharraf, Mashrura, Dept. of Mechanical EngineeringTowards human centered intelligent ships for winter navigation

Empowering quantum nanoelectronic devices using thermal energy (THEPOW) (consortium)Mttnen, Mikko, Dept. of Applied Physics, AaltoPekola, Jukka, Dept. of Applied Physics, Aalto

Parkkonen, Lauri, Dept. of Neuroscience and Biomedical EngineeringDevelopment and application of magnetoencephalography to non-invasive studies of animal brain function

Polojrvi, Arttu, Dept. of Mechanical EngineeringDiscrete Element Modeling of Continuous Ice Floes and Their Interaction (DEMFLO)

Roncoli, Claudio, Dept. of Built EnvironmentAdaptive and Learning Control strategies for Sustainable future Traffic Operations (ALCOSTO)

Adaptive Multi-Energy Virtual Power Plant for a Complex of Buildings (consortium)Sierla, Seppo, Dept. of Electrical Engineering and Automation, AaltoAlanne, Kari, Dept. of Mechanical Engineering, Aalto

Solowski, Wojciech, Dept. of Civil EngineeringHow to increase the use of low CO2 emissions soil improvement methods: development of new design procedures based on advanced Material Point Method simulations

Trm, Pivi, Dept. of Applied PhysicsCorrelations in multiband quantum systems

In-situ equilibrium shifting in CO2 utilization reactions by novel absorbents (CO2Shift) (consortium)Uusi-Kyyny, Petri, Chemical and Metallurgical Engineering, AaltoLehtonen, Juha, VTT Ltd

Further information on funding decisions from theAcademy of Finland website

This article was first published on 22 June by Aalto University.

Read more here:

Aalto University scoops 18M in Academy of Finland research funding - Science Business

The Ecosystem: leather is so over, but what comes next? – Science Business

In the beginning, the attraction of fake leather was ending the connection with slaughtering animals, but now the goal is sustainability and the circular economy. This means abandoning the plastics that go into many fake leathers, and connecting with sustainable resource streams. Start-ups have been quick to pounce on this opportunity, first in the US and increasingly in Europe.

Their solutions range from animal cell cultures that grow tissues similar to skin, to materials produced by bacteria, fungi or plants. US start-ups arguably have a head-start in this market, but the Europeans think everything is still in play.

At the current stage, there is room for everyone. Companies want this material, and we are still far from seeing it rolled out at scale, said Lucas Fuhrmann, co-founder and chief executive of Revoltech, a sustainable leather start-up based in Darmstadt that has just closed a seven-figure seed funding round.

For Ldia Kuti, co-founder and chief executive of Estonian start-up Smobya, consumer pressure is driving the market. There are a lot of fashion companies who have had feedback saying that if they dont have vegan materials for certain kinds of bags or shoes, customers will just go to another designer. So I think the market still has huge potential.

The main advantage the US start-ups have is money. They have much more capital than we have in Europe, said Fuhrmann, but Im still pretty confident about the network we have here: the R&D possibilities, the suppliers, production partners and clients. We just have to make up for the lack of capital by leveraging that network.

Success will ultimately depend on scalability and price, Kuti thinks. At this stage, most of the technologies we know about are still very expensive, and still not fully scaled, so there is still a lot of room on the market.

This optimism exists despite a lacklustre showing from EU policymakers when it comes to sustainable textiles as a whole. It took two years for the European Commission to publish its Strategy for sustainable and circular textiles, time which critics in the European Parliament, such as Christian Ehler, said could have been used to get underpinning research underway.

A few projects did emerge towards the end of Horizon 2020, such as textile recycling initiative SCIRT and circular economy data project Trick, which has a pilot project on textiles and clothing. Projects specifically addressing the leather market are few and far between, but include My-Fi, which is working with fungal mycelium, the vegetative stage of mushrooms.

So, when you talk to sustainable leather start-ups, it is striking that the impetus often comes from the fashion industry rather than the science base. Most founders have to go looking for chemists and biologists to help develop their ideas.

Faux leather from hemp

Revoltech began with Fuhrmanns disenchantment at the green credentials of a fashion company where he was working as an intern in 2015. So, he set out to see if a genuinely sustainable approach to textiles was possible, in particular from agricultural by-products. He was joined by two school friends, Julian Mushvel and Montgomery Wagner, the former with a background in engineering.

Several years of research and development at the Technical University of Darmstadt followed, resulting in a novel process that takes residual material from hemp farming and turns it into a leather-like material through treatment with bacteria. Only plant-based additives are used to finish the material, which has the brand name LOVR.

Revoltech was founded in 2021 and quickly set out to raise funds, closing its seed round in May. Its first target market is footwear, but R&D partnerships are also being negotiated with companies in the fashion, furniture and automotive sectors. We are seeing a crazy amount of interest in this kind of material.

Balancing durability and biodegradability has been a challenge. People want, and we want, a product that returns to nature, but if it only lasts for a short period of time, thats also not sustainable. And thats the narrow corridor we have to navigate.

Durability also determines the markets a leather-like material can enter. In the automotive industry, it has to be hard-wearing and retain its properties for 10 years or more, while in fashion two to three years is acceptable. In the car industry, for example, the requirements for the material are very high, and our material is not at that stage yet, so it is a matter of doing more R&D to get it there.

In the short term, clients want a substitute that looks and feels like leather, but there is also an appetite for sustainable materials with other characteristics. I think the typical embossing and grain that you have on leather is not going to be so much in demand when you look five to ten years ahead, Fuhrmann said.

Leather from kombucha

Smobya, based in Budapest and Tallinn, is developing a technology inspired by the fermented drink kombucha. The culture that drives the fermentation generates a mass of cellulose fibres, which when dried out feels a little like leather. Kuti was working in the fashion industry when she started playing around with kombucha around 2017, picking up on ideas already being developed by BioCouture, an open source network of researchers working on sustainable materials.

I created some samples from kombucha for the Central European Mercedes Benz fashion week future of fashion competition, Kuti said. The material was not very good, we couldnt create a complete sheet, it was not at all durable, but it was a really interesting experience and I saw some kind of potential in it.

The idea stayed with her when she went to study law in the UK, and she started looking for chemists and biologists who could help her build a better material. The process that Smobya set out to commercialise in 2019 is now a long way from kombucha, although it still uses a combination of bacteria and yeasts to grow sheets of bacterial nano-cellulose fibres. These are then coated with plant-based additives to give it the desired durability and water resistance, making the final product petroleum-free. Its a huge advantage for us at this stage that we dont have any plastic in our leather, said Kuti

Effort has also gone into creating a circular economy business model. The raw materials for the fermentation are by-products from the brewing and wine industries, and options are being explored for using the residues produced by the process as agricultural fertiliser.

Smobya has just passed through Estonias Beamline innovation accelerator and is currently raising pre-seed funding. Kuti expects to close the round in October. Work is still underway to perfect the material, and in particular its biodegradability. This is one of the biggest challenges for anyone creating this kind of material. You have to get the coating right, and we are still in the last stages of our R&D process, she said.

As for markets, Kuti expects the companys first targets to be in fashion, such as footwear, and design. We are not only trying to imitate leather, but we are also creating a novel transparent material, which is strong and supple. Our customers are sometimes more interested in that than the leather-like material. This could have interesting interior design applications, for example in lighting.

Pivoting away from leather

Having a broad approach is healthy in this market, according to Mari-Ann Meigo Fonseca, co-founder and chief operating officer of Gelatex, also from Estonia. Comparing yourself with leather means that people expect exactly the same behaviour and durability, and it is impossible to achieve an exact copy of leather if it is not leather. She recommends that companies have other novel materials in their portfolio. It might be a little bit harder in the beginning to explain what the material is, or how it can be used, but in the end, it is better to be something completely different.

Gelatex is interesting because it started out working on sustainable leather, but then pivoted to other materials. Once again, Fonseca had a background in the clothing industry, and went looking for researchers working on sustainable textiles. She found them at the University of Tartu, developing materials made from gelatin nanofibres. One of these was a leather-like material, and in 2016 she and Mrt-Erik Martens from the research group set up the company to take it to the market.

Our idea was to take waste from the meat and leather industries, turn it into gelatin, and then make textiles from it, she said. Chemically our material was very similar to leather, so the way it behaved was also very similar, but it came in rolls, so it was much easier to use than leather in production.

The company attracted a lot of interest and encouragement, including winning some awards, but doubts began to creep in about its direction. First of all, the balancing act of making a material that is both durable and biodegradable was proving tricky to achieve. And second, the waste they were using was still considered an animal product. We were always swimming against the tide, because it was not a vegan material, she said.

The companys pivot came from a technology it had developed to satisfy its own need to produce nanofibres on a large scale. When the COVID-19 pandemic started, it used this with other raw materials to make filtration fabrics for face masks, and this prompted a deeper investigation of nanofibres. They can be used in so many applications, from wound care, medicine and tissue engineering, through to cell-cultured meat, filtration materials, and energy storage. And the problem is how to produce them on a large scale. So, we decided to pivot and put our effort into that, where we can be the best, Fonseca said.

Based in Tallinn, Gelatex currently has a staff of 11, and last year completed a 1.2 million seed round. Fund raising on its next round now under way. It has chosen to concentrate on the cultured meat market, making microcarriers that help cells proliferate in bioreactors, and 3D scaffolds that support muscle tissue formation, in order to achieve a structured steak-like meat. While this work is entirely plant-based, Gelatex is still thinking of gelatin for other applications, for example in the medical space. But it has left sustainable leather behind.

We realised that using nanofibres to make a leather-like material, or any textile that needs to be inexpensive, is a little bit like fishing with dynamite. Its too much. Nanofibres are high-tech materials, and we are lowering their value a little bit when using them in textile materials, Fonseca said.

Elsewhere in the Ecosystem

Go here to read the rest:

The Ecosystem: leather is so over, but what comes next? - Science Business

50 Percent of Women in STEM Careers Ready to Join Great Resignation in New Gotara REACH Report – PR Web

"Its easy to blame managers, but its not their fault. They are not the root cause. While serious commitments are being made to help managers become more aware of DEI efforts, many managers dont know where to begin to truly become an agent of change," said D. Sangeeta, founder and CEO of Gotara.

SEATTLE (PRWEB) June 28, 2022

The Great Resignation is far from over for women in careers in Science, Technology, Engineering and Mathematics with 50 percent of STEM + women ready to quit their job. Gotara (http://www.gotara.com), creator of the leading global career growth platform for women in STEM +, today announced its REACH Report results for the first half of 2022. Gotara has more than 13,000 members across 160 countries, and recently surveyed its women in STEM + (members and non-members alike) for the Gotara REACH Report offering a post-pandemic analysis to capture the state of STEM+ womens careers. The average years of experience of those who participated was 13.5, creating a significant brain drain and negative impact on diversity and inclusion efforts if the challenges of attrition arent quickly and systemically addressed.

In 2021, a record 48 million people (about twice the population of Texas) quit their jobs, according to the US Bureau of Labor Statistics. This became known as the Great Resignation. Throughout the pandemic, women were at the forefront of the Great Resignation, with payroll provider Gusto finding that the quit rate for all women was 1.1 percentage point higher than men.

Employers Must Brace for Immediate and Continued Resignations of STEM + WomenAccording to the Gotara Reach Report, 50 percent of those surveyed said they are planning to leave their job, with 56 percent of these women indicating they plan to leave in 0 to 3 months, 15 percent before the end of the year, and 28 percent next year. Even before the pandemic, Gotara found that up to 40 percent of STEM + women were quitting within 5 to 7 years after launching their careers, compared to a 23 percent attrition rate of men. When women in STEM + leave, a companys intellectual property also leaves, slowing innovation, dulling competitive edge, and dampening top-line growth and margins.

Contrary to popular belief, the Gotara REACH report highlights that when it comes to women in the STEM + workplace in a post pandemic world, womens reasons for still wanting to join the Great Resignation are not primarily about compensation, benefits, or struggling to balance work and family life, said D. Sangeeta, founder and CEO of Gotara.

The Real Reasons STEM + Women Want to QuitThe primary reasons women report wanting to leave their jobs? Top of the list is non-supportive managers (27%), followed by lack of opportunities for promotion (18%), and a tie between lack of recognition (12%) and lack of communication (12%). Additional reasons reported were not having remote work opportunities (10%), being overworked (9%), not being heard (6%), and having low or non-competitive compensation (6%).

In addition, 36 percent of those who reported wanting to quit their job rated their companys efforts to hire, retain, and accelerate careers of STEM + women as poor to very poor. Ninety-nine percent of those considering leaving said that senior management at their company does not truly engage in diversity and inclusion efforts that led to positive outcomes, with 69 percent indicating that they do not have allyship initiatives. Those preparing to leave overwhelmingly rated their companys culture as authoritative, not collaborative.

Sangeeta continued, Its easy to blame managers, but its not their fault. They are not the root cause. While serious commitments are being made to help managers become more aware of DEI efforts, many managers dont know where to begin to truly become an agent of change.

Being Unhappy and Wanting to Quit Job Negatively Impacts LifeUnhappiness at work does not stay at work. It follows employees' home and into virtually every aspect of their lives. Our research found that 100% of women preparing to leave reported that their primary reasons for leaving negatively impacted their life, including a negative impact on mental health (54%), finances (28%) and the relationship with their children (13%).

By the end of 2021, many American adults found themselves in the worst mental state in years. According to the US Census Bureau, 47 percent of adults reported symptoms of anxiety, 39 percent reported symptoms of depression, and 1 in 5 adults disclosed suffering from a mental illness. Add that to the stress women preparing to leave their jobs are already feeling.

Empowered and Valued Women in STEM + Key to Diversity and InclusionWhere women continue to be vastly under-represented in areas like engineering (15%), computing (25%) and physical sciences (40%), Gotara found that 53 percent of women do not always feel empowered to recruit women into their organizations. In fact, 26 percent rarely to never feel empowered to recruit women into their organization. Overall, 81percent of women in STEM + jobs reported that they do not always feel valued in their contributions at work, and77 percent said they do not always feel included at work.

Let's face it. If a woman doesnt feel valued in her workplace she isn't going to recruit someone. In fact, she may join the Great Resignation like many of her colleagues, said Michael Alicea, Chief Human Resource Officer at Trellix. "Employees deserve more from their workplace, which is why we partnered with Gotara. Not only do we get actionable data to the root cause of retention and attrition, we get a platform for upskilling, coaching, and mentoring to accelerate womens careers as we build the premier home for diverse cybersecurity talent.

About the REACH ReportThe Gotara REACH report is produced by Gotara twice per year. First, a mid-year report in June and then another in January. Both reports are designed to help employers explore various aspects and insights of how to help women and their managers succeed in the STEM + workplace. This includes talent trends, root causes of attrition, approaches to address attrition, to grow them into leaders and to create a pipeline for senior leadership roles. REACH stands for Risk, Empathy, Analytics, Communication, and Hunger, which Gotara believes are the core skills to succeed in the digital information agein which products are launched fast and markets whipsaw.

Download the full Gotara REACH report for complete insight.

About GotaraGotara is a global AI/ML career growth platform for women in STEM +. Gotaras STAR Programs offer women nano-learning opportunities in mentoring, coaching, and upskilling. Our innovative methods accelerate womens STEM careers and support companies that truly care about recruiting, retaining, and growing a diverse workforce. Founded by D. Sangeeta, a 27-year career STEM woman with 27 patents, Gotara believes that a diverse workforce in STEM + has the power to create more innovative, sustainable, and prosperous outcomes for individuals and their organizations. More at https://www.Gotara.com.

Read this article:

50 Percent of Women in STEM Careers Ready to Join Great Resignation in New Gotara REACH Report - PR Web

Meet our Sustainability Awards Jury & see what they think about the 2022 program – Architecture and Design

After 16 years, the 2022 Sustainability Awards are now officially Australias longest running and most prestigious awards program entirely dedicated to celebrating excellence in sustainable design and architecture in the built environment.

As the Awards bring together practitioners, commentators, suppliers, products and the wider architecture and design community, it also reinforces sustainability front and centre, as an integral component of every design as it should always be.

Committed to championing the design environment on every level, its scope and reach continues to grow, ensuring a field of entries that truly reflects the diversity and innovation of the industry.

So in order to judge this years entries we have brought together a group of the higher calibre who, through their commitment, passion, insight and expert knowledge, are ready to pronounce the best sustainably designed projects and products of 2022.

So lets meet the 2022 Sustainability jury and hear what sone of them have to say about this years Awards program.

Lead judge Dick Clarke is principal of Envirotecture, is an Accredited Building Designer, with 45 years experience, focusing exclusively on ecologically sustainable and culturally appropriate buildings, as well as sustainable design in vehicles and vessels, and has received many Design Awards.

He is Director of Sustainability, and Past President of the NSW Chapter, of the Building Designers Association of Australia. He is a Past President and Board Member of the Association of Building Sustainability Assessors (ABSA). He is on the Board of Renew (Alternative Technology Association), has sat on the Australian Sustainable Built Environment Council (ASBEC) and has been design director of many hundreds of projects over 45 years, with sustainability as the major driver over that whole period (with the ever-changing understanding of what sustainability is), and his work has covered a wide variety of project sizes and types.

His one bit of advice to prospective entrants is: We know youve done good work, submit it, and tell the world!"

Mahalath Halperin, FRAIA, is an architect and environmental consultant living and working in regional NSW.

As well as running an architectural practice since the 1990s, addressing everything from domestic renovations through to large commercial buildings, resorts and education facilities, she also conducts energy and environmental audits and assessments, and has always tried to tie the scientific with the aesthetic to achieve highly sustainable but liveable works where possible.

Mahalath has also developed and delivered courses on environmental and architectural issues, and is also a published author, including assorted childrens books, including one about her cat building a house.

Mahalath Halperin Architects won the Single Dwelling, New category for Drumkerin at Sustainability Awards 2018.

Mahalath says that For me its all about the total package addressing as many issues as possible to the best outcome. Rather than a project that does something to 120% and ignores the rest, Id rather see architecture that is 90% efficient for 90% of the issues for 90% of the time, and it has to feel good and look good too!

Were way past the PVs on the roof with some good insulation and solar hot water. Its time to embrace the whole package not just the wrapping paper, she says.

Kate Nason is a passionate advocate of high-performance, healthy and resilient buildings. With a background as an architect (ARBV) she has worked across multiple low-energy buildings including Certified Passive House projects such as the Monash Gillies Hall and several single residential homes utilising low carbon prefabricated construction systems.

She is a certified Passive House Designer (PHI), Green Star Accredited Professional and Chairperson at the Australian Passive House Association. She holds the role as Sustainability Advisor at Frasers Property Australia, working across the development of the corporate sustainability strategy and project oversight in Victoria, Queensland and Western Australia, ensuring buildings and master planned communities integrate leading sustainability objectives and targets.

Says Kate: It is such a privilege to be on the judging panel for the 2022 Sustainability Awards. With carbon emission reductions and health having been in such a spotlight over the past year, I am particularly keen to see entries that demonstrate rigor and transparency around their sustainability claims. I am also looking forward to getting a glimpse into the extensive collaboration happening behind the scenes for example how operational and embodied energy analysis has been translated into design decisions around envelope detailing, material selections, service engineering, construction processes, and end user considerations.

A bonus for me, she says, would be to see entries with evidence around as-built performance either through onsite verification results, such as blower door testing, or monitoring data revealing indoor environmental quality, energy and water consumption as well as onsite renewable energy generation and biodiversity support. Our built environment can be hard-wired to provide ongoing sustainability outcomes for both people and the planet, and I am extremely excited to see how the industry has been responding to this challenge over the past year.

Dr Arianna Brambilla is a senior lecturer at the School of Architecture, Design and Planning, the University of Sydney, and co-chair of the Building Efficiencies cluster within the smart sustainable building network (Sydney Nano). Her expertise lies at the merging borders of architecture, construction, building physics, and engineering, drawing upon the different disciplines to propose an innovative approach to design and construction. Her research offers a novel philosophical design approach in which buildings, new or renovated, are in balance with nature and become restores or regenerators for the environment instead of being consumers of resources.

I hope to see innovative design approaches beyond energy efficiency that tackle whole-of-a-life performances and keep users at their cores.

I expect the winners to be exploratory examples of buildings as restores of our ecosystem and society, she notes.

Jeremy Spencer is a long-time builder, thermal performance assessor, and Director at Design & Building company Positive Footprints. Positive Footprints is a multi-award winning construction company, dedicated to making high performance sustainable homes and renovations easy to achieve and affordable. His company has worked for the last 19 years to show that energy efficient design and high-performance construction is a cost effective option and can be a mainstream reality. Jeremy currently sits on the Design Matters National board, the NatHERS Stakeholder Committee, and the board of directors for Builders Declare. An educator, and previous Master Builders GreenLiving instructor, he says that he is passionate about spreading environmentally sustainable design, and the knowhow needed to make the residential construction industry the first carbon neutral industry in Australia.

Oliver Steele has a stellar 25-year track record of sustainable design & construction, winning numerous awards.

His mission is to show the world that sustainable development works for people, industry, and the planet. To prove that people want healthy, comfortable homes that cost less to live in; and that it makes dollars and sense for developers to provide them now and into the future.His team delivered FERN, the first Passivhaus certified apartments in the southern hemisphere, as well as Australias first green-roofed terrace houses at 88 Angel St, Newtown.

Im hoping to see projects founded on solid building physics with demonstrable sustainability outcomes, as well as a nod to the fickle spirit that makes us human, he says.

Simone Schenkelis a certified Passive House designer and the founder at Gruen Eco Design, whose mission is to make energy efficient homes a staple in the Australian landscape. Everyone should have the right to live in a comfortable house that does not cost the earth!She has used the passion, experience and knowledge she gained from her upbringing and architectural studies in Germany to create Gruen Eco Design. A business where she works with her clients to create not only beautifully designed homes that wont cost the earth. But also homes that are healthy, thermally comfortable, energy efficient and resilient for future generations.I am very excited to be a part of this years jury for the Sustainability Awards. Entries are now open for all categories. Sustainability is such an integral part of design and architecture; it cannot be an afterthought; it has to be the driver in all that we do, says Simone.

I am looking forward to celebrating and promote the trailblazers and leaders in sustainable design. Im excited to see designs that not only incorporate and showcase a real passion for a considerate environmental design. But to showcase that those highly energy efficient and sustainable dwellings can also be absolutely stunning, beautiful and innovative, she says.

Suzanne Toumbourouis the Chief Executive Officer of the Australian Council of Recycling (ACOR).

Suzanne is an organisation leader with deep experience in public affairs, executive management, stakeholder relations, governance strategy of not-for-profits, with a strong reputation as a sustainability and circular economy subject matter expert. Prior to ACOR, Suzanne was the longstanding Executive Director of the Australian Sustainable Built Environment Council, where she delivered impactful policy outcomes for building sustainability, including advancing the energy performance provisions in Australias Building Code and informing the priorities of the COAG Energy Councils Trajectory for Low Energy Buildings.

Suzanne says that she is passionate about leading positive change for people, industry and the environment.

David Coates lives and breathes sustainability and has been delivering beautiful buildings that perform to an exemplar level in both sustainability and practicality. David specialises mainly in urban designs, with over 25 years of experience working within the building industry.

Davids vision is all about efficiency of performance and reusing and up cycling. His projects achieve high end energy efficiency ratings in the NatHERs score system, and as well as energy efficiency, his projects regularly contain old building materials upcycled form their former dwellings. David and his team even built an entire sustainable development using no mains power from an off-grid onsite power station, described by Renew Magazine as an industry first.

I want to see something different, ideas that are within reach of the average homeowner and something that take us into the future, notes David.

For those that want to enter, there is still time.

Go to https://www.sustainablebuildingawards.com.au/#s-categories

More here:

Meet our Sustainability Awards Jury & see what they think about the 2022 program - Architecture and Design

Announcing Six Winners of the Third Annual Manning/IALS Innovation Awards : Institute for Applied Life Sciences – UMass News and Media Relations

The University of Massachusetts AmherstsInstitute for Applied Life Sciences (IALS)has announced that six campus research teams have been named recipients of the 3rd annualManning/IALS Innovation Awards. These translational grants are designed to advance applied research and development efforts from UMass-based faculty research groups in the sciences and engineering through the development of spin-out/startup companies and the out-licensing of UMass intellectual property.

Alumnus Paul Manning and his wife, Diane, committed $1 million through their family foundation to establish theManning Innovation Program. The gift provides three years of support in advancing a robust and sustainable commercialization pipeline of applied and translational research projects from UMass Amherst.

Peter Reinhart, founding director of IALS, says, We are grateful to the Manning Family Foundation and Paul Manning for their support of this exciting translational initiative. This seed fund program enables UMass Amherst start-up companies to traverse the funding valley of death towards success.

Six projects were selected from a highly competitive group of applicants. Each successful team will receive seed funding of up to $100,000 over 12 to 18 months towards achieving translational milestones. In addition, a collaborative effort from IALS, the College of Natural Sciences, the Berthiaume Center for Entrepreneurship and the Isenberg School of Management will provide support for commercialization efforts, including business training and mentorship resources.

The winning team leaders and their projects are:

View original post here:

Announcing Six Winners of the Third Annual Manning/IALS Innovation Awards : Institute for Applied Life Sciences - UMass News and Media Relations

Pressure BioSciences Awarded Second U.S. Patent for Its Revolutionary Ultra Shear Technology Platform, for Its Innovative NanoGap Valve – Yahoo…

Dynamically-Adaptive Compact Valve is Key Component in the Company's Highly Anticipated and Proprietary UST Platform; UST Expected to Help Deliver Strong Sales Growth and Profitability in 2022

SOUTH EASTON, MA / ACCESSWIRE / November 11, 2021 / Pressure BioSciences, Inc. (OTCQB:PBIO) ("PBI" or the "Company"), a leader in the development and sale of broadly enabling, pressure-based instruments, consumables, and specialized services to the worldwide life sciences, agriculture, cosmetics, food & beverage, and other industries, today announced the award of its second U.S. patent for its revolutionary Ultra Shear Technology (UST) platform. Entitled "Ultrahigh Pressure Compact Valve with Throttling Capability", this new patent (US 11,156,295) brings the Company's intellectual property ("IP") estate to a total of seven UST patents (two in the U.S.) and 30 pressure-based patents worldwide.

The Company's UST platform was created to revolutionize the processing of immiscible liquids (typically oils and water) - usually processed into macro/micro emulsions - into high quality, highly valuable, long-term stable nanoemulsions. Emulsions are mixtures of two or more liquids that are normally not soluble in each other without the addition of chemicals called emulsifiers (e.g., surfactants). Emulsions are used in thousands of products in everyday use, such as in dairy products, lotions and creams, drugs and vaccines, and nutraceuticals. Scientific data indicate that higher bioavailability and improved absorption in humans, animals and plants, plus greater stability, lower surfactant levels, and other advantages (such as more reliable dosing control) are vastly improved by high quality nanoemulsions versus micro or macroemulsions.

Dr. Edmund Y. Ting, Sr. Vice President of Engineering and an inventor on this patent, said: "The conversion of a coarser emulsion into a high-quality nanoemulsion with ultra-low droplet size is made possible by intense fluid shear forces created from pressure driven fluid velocity. By using pressures up to 60,000 psi to drive fluid flow, we believe that UST achieves a disruptive shear capability greater than any homogenizer on the market today. UST also achieves higher flow rates and lower processing costs than current high-pressure homogenizers by leveraging the use of field proven pumps, patented pressure transfer isolators, and our now patented, self-throttling Nanogap valve. The unique design of this compact, self-throttling valve is dynamically-adaptive, delivering clog and erosion resistance, with extraordinary precision and control in producing fine nanoemulsion dispersion size."

Story continues

Dr. Alexander V. Lazarev, Chief Science Officer, commented: "We are proud to see our work recognized with yet another strong patent. Amongst the exciting applications of our UST platform are enormous opportunities in the efficient and affordable production of stable nanoemulsions. Nanoemulsions are promising revolutionary advances in food/beverage, nutraceutical, personal care, pharmaceutical, agriculture, as well as many other industries. The UST process features exquisite control of high shear energy, resulting in a very reproducible product with a narrow distribution of droplet sizes as small as 40 to 100 nanometers. Such tiny, nano-sized oil droplets lead to greater stability and higher bioavailability of the active ingredients contained in the oil phase, resulting in more nutritional and better tasting liquid foods and beverages, as well as significantly higher quality drugs and vaccines in dosing and delivery."

Mr. John B. Hollister , Director of Marketing and Sales, stated, "The daily market interest we are receiving in UST-produced nanoemulsions prior to significant active promotion activities is very exciting. The potential benefits of nanoemulsified products are now recognized by important market leaders globally. The 2021 worldwide market size for a number of industries that could benefit from UST are each in the tens and even hundreds of billions of dollars. Over the past year, we have been working with major players in several of these markets to create unique formulations, the results of which have been embraced by these prospective partners. These companies are exerting tremendous pressure on us to release the commercial-scale, UST systems as quickly as possible. We believe the amount of nanoemulsified product required to meet these customers' needs will clearly help us achieve our goals of strong sales growth and profitability in 2022."

For more information on PBI's innovative UST, BaroFold, and PCT Platforms, and on the Company's new PBI Agrochem Division, please use the link to follow Mr. Schumacher's interview on Benzinga's ALL ACCESS Investor Event on Thursday, November 4, 2021. Schumacher Interview ALL ACCESS 11.4.21

About Pressure BioSciences, Inc.

Pressure BioSciences, Inc. (OTCQB: PBIO) is a leader in the development and sale of innovative, broadly enabling, pressure based solutions for the worldwide life sciences and other industries. Our products are based on the unique properties of both constant (i.e., static) and alternating (i.e., pressure cycling technology, or PCT) hydrostatic pressure. PCT is a patented enabling technology platform that uses alternating cycles of hydrostatic pressure between ambient and ultra-high levels to control biomolecular interactions safely and reproducibly (e.g., cell lysis, biomolecule extraction). Our primary focus is in the development of PCT- based products for biomarker and target discovery, drug design and development, biotherapeutics characterization and quality control, soil & plant biology, forensics, and counter-bioterror applications. Additionally, major new market opportunities have emerged in the use of our pressure-based technologies in the following areas: (1) the use of our recently acquired, patented technology from BaroFold, Inc. (the "BaroFold" technology) to allow entry into the bio-pharma contract services sector, and (2) the use of our recently-patented, scalable, high-efficiency, pressure-based Ultra Shear Technology ("UST") platform to (i) create stable nanoemulsions of otherwise immiscible fluids (e.g.,oils and water) and to (ii) prepare higher quality, homogenized, extended shelf-life or room temperature stable low-acid liquid foods that cannot be effectively preserved using existing non-thermal technologies.

Forward Looking Statements

This press release contains forward-looking statements. These statements relate to future events or our future financial performance and involve known and unknown risks, uncertainties and other factors that may cause our or our industry's actual results, levels of activity, performance or achievements to be materially different from any future results, levels of activity, performance or achievements expressed, implied or inferred by these forward-looking statements. In some cases, you can identify forward-looking statements by terminology such as "may," "will," "should," "could," "would," "expects," "plans," "intends," "anticipates," "believes," estimates," "predicts," "projects," "potential" or "continue" or the negative of such terms and other comparable terminology. These statements are only predictions based on our current expectations and projections about future events. You should not place undue reliance on these statements. In evaluating these statements, you should specifically consider various factors. Actual events or results may differ materially. These and other factors may cause our actual results to differ materially from any forward-looking statement. These risks, uncertainties, and other factors include, but are not limited to, the risks and uncertainties discussed under the heading "Risk Factors" in the Company's Annual Report on Form 10-K for the year ended December 31, 2020, and other reports filed by the Company from time to time with the SEC. The Company undertakes no obligation to update any of the information included in this release, except as otherwise required by law.

Investor Contacts:

Richard T. Schumacher, President and CEO(508) 230-1828 (T)

Alexander V. Lazarev, Ph.D., Chief Science Officer(508) 230-1829 (F)

Edmund Y. Ting, Sc.D., Sr. VP Engineering

For more information about PBI and this press release, please click on the following website link:http:/www.pressurebiosciences.com Please visit us on Facebook, LinkedIn, and Twitter.

SOURCE: Pressure BioSciences Inc.

View source version on accesswire.com: https://www.accesswire.com/672314/Pressure-BioSciences-Awarded-Second-US-Patent-for-Its-Revolutionary-Ultra-Shear-Technology-Platform-for-Its-Innovative-NanoGap-Valve

The rest is here:

Pressure BioSciences Awarded Second U.S. Patent for Its Revolutionary Ultra Shear Technology Platform, for Its Innovative NanoGap Valve - Yahoo...

Lecturer Positions in Intelligent Systems Engineering job with Indiana University Bloomington / Luddy School of Informatics, Computing, and…

The Luddy School of Informatics, Computing, and Engineering atIndiana University-Bloomington invites applications for twofull-time non-tenure track lecturer positions in Intelligent SystemEngineering, beginning in August 2022. We are particularlyinterested in candidates who can prepare and deliver courses inComputer Engineering and Cyber-physical Systems, potentially withapplications in Nanoengineering and Bioengineering.Desirable skills include systems programming, systems design, andprototyping.

In addition to course responsibilities, lecturers will also beresponsible for supervising associate instructors assigned to theirclasses, development of laboratory material, grading, and otherduties as assigned.

After successfully completing a probationary period, lecturerswill be eligible for long-term contracts and promotion to a SeniorLecturer position. Salary will be commensurate withqualifications and experience.

Candidates should possess a Masters of Science (MS) or higherdegree in Informatics, Computer Science, Information Science,Engineering, or a related discipline, or equivalent testedexperience such as experience and mastery in industry, and shouldbe able to demonstrate a record of teaching excellence andenthusiasm.

Applicants should preferably have two academic years experience(may be part-time). Luddy School seeks candidates prepared tocontribute to our commitment to diversity and inclusion in highereducation.

Lecturers at Indiana University are valued members of thefaculty and are expected to support the teaching mission of theLuddy School through excellence in pedagogical practice, service tothe school and academic programs, and inquiry into the advancementof pedagogy in computing.

Bloomington is a culturally thriving college town with amoderate cost of living and the amenities for an active lifestyle.IU is renowned for its top-ranked music school, high-performancecomputing and networking facilities, and performing and finearts.

Online applications received before December 12, 2021 will beassured full consideration; however, the search will remain openuntil a suitable candidate is found. Candidates should reviewapplication requirements, learn about IU, Luddy School, andbenefits, and apply online at:

https://indiana.peopleadmin.com/postings/11514

Questions may be emailed: bhimebau@indiana.edu

Indiana University is an equal employmentandaffirmative action employerand a provider of ADAservices. All qualified applicants will receive consideration foremployment without regard to age, ethnicity, color, race, religion,sex, sexual orientation, gender identity or expression, geneticinformation, marital status, national origin, disability status orprotected veteran status.

Read more from the original source:

Lecturer Positions in Intelligent Systems Engineering job with Indiana University Bloomington / Luddy School of Informatics, Computing, and...

NVIDIA Announces Jetson AGX Orin: Modules and Dev Kits Coming In Q1’22 – AnandTech

Today as part of NVIDIAs fall GTC event, the company has announced that the Jetson embedded system kits will be getting a refresh with NVIDIAs forthcoming Orin SoC. Due early next year, Orin is slated to become NVIDIAs flagship SoC for automotive and edge computing applications. And, has become customary for NVIDIA, they are also going to be making Orin available to non-automotive customers through their Jetson embedded computing program, which makes the SoC available on a self-contained modular package.

Always a bit of a side project for NVIDIA, the Jetson single-board computers have none the less become an important tool for NVIDIA, serving as both an entry-point for helping bootstrap developers into the NVIDIA ecosystem, and as a embedded computing product in and of itself. Jetson boards are sold as complete single-board systems with an SoC, memory, storage, and the necessary I/O in pin form, allowing them to serve as commercial off the shelf (COTS) systems for use in finished products. Jetson modules are also used as the basis of NVIDIAs Jetson developer kits, which throw in a breakout board, power supply, and other bits needed to fully interact with Jetson modules.

With NVIDIAs Orin SoC set to arrive early in 2022, NVIDIA is using this opportunity to announce the next generation of Jetson AGX products. Joining the Jetson AGX Xavier will be the aptly named Jetson AGX Orin, which integrates the Orin SoC.

Orin featuring 12 Arm Cortex-A78AE Hercules CPU cores and an integrated Ampere architecture GPU with 2048 CUDA cores, adding up to 17 billion transistors, Given Orin's mobile-first design, NVIDIA is being fairly conservative with the clockspeeds here; the CPU cores for Jetson AGX Orin top out at 2GHz, while the GPU tops out at 1GHz. Otherwise, the SoC also contains a pair of NVIDIAs latest generation dedicated Deep Learning Accelerators (DLA), as well as a vision accelerator to further speed up and efficiently process those tasks.

Rounding out the Jetson AGX Orin package, the Orin SoC is being paired with 32GB of LPDDR5 RAM, which is attached to a 256-bit memory bus, allowing for 204GB/second of memory bandwidth. Meanwhile storage is provided by a 64GB eMMC 5.1 storage device, which is twice the capacity of the previous generation Jetson AGX.

All told, NVIDIA is promising 200 TOPS of performance in INT8 machine learning workloads, which would be a 6x improvement over Jetson AGX Xavier. Presumably those performance figures are for the modules full 50W TDP, while performance is proportionally lower as you move towards the modules minimum TDP of 15W.

Meanwhile, for this generation NVIDIA will be maintaining pin and form-factor compatibility with Jetson AGX Xavier. So Jetson AGX Orin modules will be the same 100mm x 87mm in size, and use the same mezzanine connector, making Orin modules drop-in compatible with Xavier.

Jetson AGX Orin modules and dev kits are slated to become available in Q1 of 2022. NVIDIA has not announced any pricing information at this time.

Originally posted here:

NVIDIA Announces Jetson AGX Orin: Modules and Dev Kits Coming In Q1'22 - AnandTech

Novel Imaging Technique Takes High Resolution 3D Images of Cells – AZoNano

A team of researchers at the Swiss Federal Institute of Technology has developed a high-performance Scanning Ion Conductance Microscope (SICM) using the latest advances in nanopositioning, nanopore fabrication, microelectronics and controls engineering.

Image Credit: Shutterstock.com/ Meletios Verras

Time-resolved scanning allows the 3D visualization of dynamic structures in a eukaryotic cell membrane at nanometer resolutions.

Studying the functions of living cells and organelles at the nanoscale is vital to understanding the causes of disease. Traditional approaches, including electron microscopy, may, unfortunately, damage these cells.

The Swiss researchers developed a SCIM microscope that resolves spatiotemporally diverse three-dimensional processes on a eukaryotic cell membrane at sub-5 nanometer axial resolution. This may offer insights into intracell interactions in the fight against infections and disease.

Studying the intricate functions of living cells at the nanoscale is a unique challenge. Researchers have developed a range of techniques to meet this challenge, including atomic force microscopy (AFM), scanning tunneling microscopy (STM) and Scanning Probe Electrochemistry (SPE).

Scanning probe microscopy (SPM) forms images of surfaces using a probe that scans the specimen. The technique made its first appearance in 1981 in the form of the scanning tunneling microscope, which produces images at atomic resolution by scanning a specimen using a probe.

In scanning probe microscopes, piezoelectric actuators move the probe with atomic-level precision controlled by electronics. The probe raster scans the specimen. It captures discrete data points which are used to form an image. Its manner of scanning is called a mode.

Scanning Ion Conductance Microscopy (SICM) was developed by P.K. Hansma and his colleagues at the University of California in 1989. An electrolyte-containing aqueous medium is a poor conductor.

A SCIM microscope scans a nanoprobe (micro-pipette with a 50 to 100 nm hole) close to the surface of the specimen. As the probe moves across the specimen, ionic currents flow through the pipette. The strengths of these currents vary according to the electrical resistance across the samples surface, thus revealing information about its composition.

In the hopping mode described by the Swiss team, however, the nanoprobe is not raster scanned. It moves vertically up and down in a hopping motion.

The probe approaches the specimen at a distance of 25 to 50 nm at specified points and retracts, thus providing discrete points of measurement from which an image is formed. Crucially, the probe never touches the specimen, thus preventing damage to the sample.

SCIM microscopy is, therefore, a powerful tool for capturing the steep changes in a cells topography without affecting the sample.

Time-resolved SICM microscopes produce high-resolution profiles of cell shapes and surface characteristics. However, these need to be correlated with biochemical information and changes to the internal organization of the cells.

The Swiss team integrated an inverted optical microscope to a SICM microscope which allowed them to combine recently developed super-resolution microscopy techniques into their approach.

The SICM setup consisted of a custom-built pipette Z-actuator (vertical actuator) integrated into a controlled-atmosphere device, critical for cell viability during imaging.

The imaging of eukaryotic cells requires piezo actuators with a long-range (>1020 m). This leads to a trade-off between resonance frequency and the range of the actuator. The team overcame this by adaptively slowing down the pipettes velocity and applying a gain to the piezo motion as a function of the current interaction curve.

The Z-actuator achieved a wide mechanical displacement amplification of 22 m scanning range on the cell surface. It was driven by a custom-made piezo controller and integrated with a stepper-motor stage for approaching the sample.

The team used borosilicate and quartz nanopipettes for probing. They were fabricated with a CO2 laser puller with a radius of 20 to 60 nm in size. Quartz capillaries were shrunk to a sub-10-nm radius using electron beam irradiation.

Many cellular processes occur at time scales of minutes or hours and are easily trackable with time-lapse SICM. Subcellular processes, such as endocytosis or infection, however, occur much faster. The Swiss teams technique combines the capability to address large imaging volumes (up to 220 000 m3) relatively quickly with high-speed SICM imaging of small details on live cells.

The wide range of measurements possible (Scan sizes from 500 500 nm2 to 100 100 m2, imaging speeds from 0.5 s/image to 20 min/image; Number of pixels per image from 1 Kp to 1 Mp; Depth of view of 22 m with axial resolution below 10 nm) significantly enhances the range of biological studies facilitated by SICM microscopy.

Leitao, S., et al., (2021) Time-Resolved Scanning Ion Conductance Microscopy for Three-Dimensional Tracking of Nanoscale Cell Surface Dynamics.ACS Nano, [online] Available at: https://doi.org/10.1021/acsnano.1c05202

Liu, B., et al., (2013) Scanning ion conductance microscopy: a nanotechnology for biological studies in live cells.Frontiers in Physiology, [online] 3. Available at: https://doi.org/10.3389/fphys.2012.00483

Disclaimer: The views expressed here are those of the author expressed in their private capacity and do not necessarily represent the views of AZoM.com Limited T/A AZoNetwork the owner and operator of this website. This disclaimer forms part of the Terms and conditions of use of this website.

Excerpt from:

Novel Imaging Technique Takes High Resolution 3D Images of Cells - AZoNano

"Dialogues between world Laureates and Gen-Z" was successfully held: an event focusing on Gen Z and the future of Science – PRNewswire

Topics discussed include the role of curiosity in scientific work, interdisciplinary research, and journalism's role in the education of the public. The discussants were unanimous on the importance of curiosity in promoting scientific research. John Hopcroft,a recipient of the 1986 A. M. Turing Award, remarked that "Curiosity is a fundamental driver of Science", similarly, Prof. Richard Zare, a recipient of the Wolf Prize in Chemistry stated that "a sense of wonder and curiosity"is more important for science than talent. It was telling that this opinion cut across generational and professional lines and is shared by Gen Z. Lending her voice to the conversation, Li Jingjing, a journalist with CGTN, added that "in journalism, you need to be curious about people and the environment" if one is to succeed.

On Interdisciplinary research, the consensus was that the best scientific research of the future would, primarily, emerge from interdisciplinary efforts. In fact, an attendee, Hou Xu, Professor at the College of Chemistry and Chemical Engineering, Xiamen University, research work straddles nano-science, material science and biology provide early evidence of this budding trend.

A glimpse of how ideas and communication can flow between Gen-Z and older generations for the benefit of all occurred when Kid the bard, a popular Chinese internet influencer, fired a barrage of questions, sourced from his social media followersat Prof. Robert Kirshner, Clowes Professor of Science at Harvard University and the recipient of the 2015 Wolf prize in physics. This event provided a unique platform for bringing these diverse groups together.

CGTN Think Tank, [emailprotected]

SOURCE CGTN Think Tank, World Laureates Association (WLA), National Communication Center for Science and Technology, CAST

The rest is here:

"Dialogues between world Laureates and Gen-Z" was successfully held: an event focusing on Gen Z and the future of Science - PRNewswire