Peterborough student nominated for The Congress of Future Medical Leaders – The Keene Sentinel

Gabrielle Klaessig of Peterborough, a homeschooled high school junior who is attending early college classes at NHTI of Concord, is a Delegate to the Congress of Future Medical Leaders on March 20 and 21.

The Congress is an honors-only program for high school students who want to become physicians or go into medical research fields. The event is intended to honor, inspire, motivate and direct the top students in the country interested in medical careers and to provide resources to help them reach their goals.

Klaessigs nomination was signed by Dr. Mario Capecchi, winner of the Nobel Prize in Medicine and the Science Director of the National Academy of Future Physicians and Medical Scientists. Klaessig was nominated to represent New Hampshire based on her academic achievement, leadership potential and determination to serve humanity in the field of medicine.

During the two-day Congress, Klaessig will join students from across the country and hear Nobel Laureates and National Medal of Science winners talk about leading medical research; be given advice from top medical school deans on what to expect; witness stories told by patients whove benefitted from advanced medicine; be inspired by fellow teen medical science prodigies; and learn about cutting-edge advances and the future in medicine and medical technology.

Based in Washington, D.C. and with offices in Boston, The National Academy of Future Physicians and Medical Scientists was chartered as a nonpartisan, taxpaying institution to help address this need for physicians by working to identify, encourage and mentor students who wish to devote their lives to the service of humanity.

For more information visit http://www.FutureDocs.com or call 617-307-7425.

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How UGA students are applying to grad schools amid COVID-19 – Red and Black

Seniors at the University of Georgia are gearing up to apply for graduate school programs as their final year on campus draws to a close. While this semester isnt what they thought it would look like, neither is the process of applying to postgraduate programs.

From law school and masters degree programs to physicians assistant school, UGA students are maneuvering their way through COVID-19s hurdles to continue their academic careers. With no certainty about fall 2021, applying to upper-level schools and programs has been more uncertain than ever.

UGA Graduate School DeanRon Walcott said the number of fall 2020 applications increased by 9%.

Walcott said changes were made to applications for COVID-19 based on the specific programs requirements.

For example, international students were permitted to submit final transcripts after registration, and some programs extended application deadlines, Walcott said. The popular language learning app Duolingo was added as an English proficiency test for international students as well, Walcott said.

Some graduate programs and schools have announced their plans for the return of students for fall 2021 while still keeping precautions in place due to the COVID-19 pandemic.

Some of the medical schools senior biology major Shea Fincher applied to will require faculty, staff, students and visitors to wear face coverings while inside campus facilities and buildings along with required social distancing inside each classroom.

Kassie Hogan, a senior majoring in biology and psychology, explained some of the major differences in applications this year as opposed to other years.

Normally schools require GRE scores, but this year none are, Hogan said. As for the lengthy interview process, Hogan said interviews will also likely be conducted over Zoom.

Some schools are waiving the Graduate Record Examination for summer and fall 2021 and or spring 2021 because of COVID-19 complications. Some of these schools include Auburn University, The University of Alabama and Florida State University, according to Study.com.

Jenna Swaboiwicz, a senior communication sciences and disorders major, also said the absence of a GRE requirement was the biggest change this year due to COVID-19. However, Swabowicz opted to take the GRE at home, a new option in the wake of the COVID-19 pandemic.

Having to take it at home with online proctoring software was completely new to me, and after the fact, having to find out which schools were still requiring it, which would consider it but not make it mandatory and which wouldn't even look at it presented a new boundary, Swaboiwicz said.

Swabowicz also said many schools held modified Zoom information sessions to promote their graduate programs. COVID aside, I think this was a really great way to get students across the country to learn about each program, Swabowicz said.

Fincher said that all of her interviews for medical school will be conducted online as opposed to normally traveling to schools for interviews.

Virtually attending interviews instead of traveling to schools helps my budget, but I believe virtual interviews can be a disadvantage in getting to know a person like you can during a normal interview process, Fincher said.

Similarly, Swabowicz said the process for choosing schools to apply to was very difficult without any in-person component of touring.

Deciding which schools to apply to without in-person information sessions and campus tours was definitely daunting, Swabowicz said.

Hogan said that the optional GRE test is the only lenient part of the application process this year as opposed to previous years.

I think it has been harder [to complete the application during COVID-19] because usually you can go to advisors or career centers and ask questions and even talk to your programs of interest, Hogan said.

Fincher said the medical school application was more difficult this year because of opportunities missed due to quarantine and COVID-19 precautionary measures.

I believe this application was harder amid the COVID-19 changes because different research and volunteering opportunities of mine were canceled or postponed over the spring until further notice, Fincher said.

This forced Fincher to find new non-contact volunteer opportunities to still have a competitive application for medical school.

Overall, I believe the application process has not changed in rigor, but instead it has adapted through the COVID-19 pandemic to better understand applicants during this stressful time, Fincher said.

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Dr Aditya Bardia Forecasts What’s to Come for the ASCENT Trial in Triple-Negative Breast Cancer – AJMC.com Managed Markets Network

Initial preliminary efficacy and safety data are expected sometime next year, stated Aditya Bardia, MBBS, MPH, breast medical oncologist, Massachusetts General Hospital, Harvard Medical School.

Initial preliminary efficacy and safety data are expected sometime next year, followed by dose expansion and a phase 2 trial, explained Aditya Bardia, MBBS, MPH, breast medical oncologist, Massachusetts General Hospital, Harvard Medical School.

Transcript

What is the timeline for the phase 1B portion of the ASCENT trial investigating sacituzumab govitecan (SG) and talazoparib?

It is still ongoing. And we hope to have at least preliminary efficacy and safety tolerability data early next year, and then after that, the trial would expand to dose expansion as well as a phase 2 trial to further confirm the efficacy and safety tolerability. But in terms of initial preliminary data, sometime next year we should have those results.

Is there a timeline for the phase 1B portion?

In part that would depend on the efficacy of the data, how robust the results look, and that would help guide for the development of phase 2 or even phase 3.

Have additional patient safety measures been implemented with flu season and the coronavirus disease 2019 (COVID-19) pandemic overlapping?

Oh, it started absolutely in March of 2020 when Boston got hit with COVID-19. The institutions in the Boston region, including MGH, implemented a number of procedures to ensure that patients with cancer are safe, and those measures remain in place. We've not seen nosocomial or hospitals spread of COVID-19. And despite the pandemic, the clinical trial with SG plus [a] PARP inhibitor continued to enroll, and we had patients enrolled even when the pandemic was at its peak.

In Boston, weve not seen any COVID infection in patients who were treated with this agent, in part because of the preventive measures that have been instituted at our institution. One thing to consider is that neither SG nor [a] PARP inhibitor necessarily would increase the risk of either flu or COVID. But we know that triple-negative breast cancer is an aggressive disease, so its important to control the disease while ensuring that we take whatever precautions are needed.

We actually wrote a report about this as a CPC, or clinical pathological conference, in the New England Journal of Medicine that was published in July, talking about a patient with breast cancer during the COVID pandemic and how it could have an impact. And the bottom line was, we have to weigh the risks and benefits and take whatever precautions are needed, but at the same time, ensure that the anticancer treatment or the care of patient with breast cancer is not compromised.

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Alpert Medical School adapts first-year anatomy course to adhere to COVID-19 guidelines – The Brown Daily Herald

Since the Warren Alpert Medical School moved the majority of its curriculum to a remote format beginning in fall 2020 to adhere to COVID-19 guidelines, lectures have been given live over Zoom or pre-recorded. The components of the curriculum that do meet in person, such as the first-year anatomy course, have been adjusted to meet social distancing requirements.

Because of the pandemic, the anatomy course no longer includes a year-long cadaver dissection, which had long been considered an integral part of the Med School experience, said Amy Chew, lecturer in ecology and evolutionary biology and one of the lecturers for the anatomy course.

Traditionally, groups of five to six students would spend about three hours a week dissecting a cadaver themselves, but this required many students to be in a confined lab space for a prolonged period of time, Chew said. Given the Centers for Disease Control and Preventions recommendations against indoor gatherings, this aspect of the course needed to evolve with the onset of COVID-19.

Med School staff now perform the dissections beforehand for the students to study later a method known as prosection, Chew said. Students are required to spend one hour a week in the lab, but during this time, only two students may be present together, which allows for enforcement of social distancing guidelines.

While the switch to prosection means that students miss out on the dissection experience, there are benefits to this teaching method, Chew said. The one major advantage is that students arent so tied up in lab, she said, adding that the new method gives medical students more time to study the content they learn during the anatomy lab outside of class.

Other medical schools had already stopped using dissection pre-pandemic, Associate Dean for Medical Education Paul George 01 MD05 said. By switching to prosection format, were actually more in line with what other medical schools are doing at this point, he added.

Students who spoke with The Herald voiced mixed feelings about the Med Schools switch to prosection.

With (COVID-19), Im grateful we get to go to the anatomy lab, Wendy Gonzalez 19 MD24 said. But I do feel like we missed out. I feel like we would remember so much more if we actually got to find everything ourselves. She believes that the more hands-on aspects of dissection would have helped her as a visual and tactile learner and better prepared her for a career in surgery.

But understanding the need for adjustment during the pandemic, Gonzalez said she thinks learning using prosection is still helpful.

Other first-year medical students prefer the prosection method.

Im somebody who is definitely not going to go into surgery, so its maybe less heartbreaking for me than for somebody whos really into anatomy and the body, said Jessica Moore MD24. Moore says she has been able to learn effectively using prosection because of her independent learning style. For me, its been a better experience, she added.

Navya Baranwal 20 MD24 said, At first I was a little apprehensive: What is my medical education going to be like? But overall I feel like its still been very meaningful and educational, and its been a nice balance of ensuring medical students safety but also (ensuring) that we have a good education.

Despite the change in the course structure, student engagement and performance has remained steady; course ratings and exam scores have been about the same as they were in past years, according to George.

In years prior, performance in the anatomy course was partly evaluated through a practical exam. But that component was eliminated in the fall, which made the efficacy of the course harder to judge, Chew said. It was replaced with 20 additional multiple choice questions on the lab material in the written exams.

It is challenging for us to try to figure out what (students) have been able to absorb from the lab without the practical exam, Chew said. I think we wont really know until these students take their step exams next year, she added.

The COVID-19 anatomy experience raises questions about the future of the Med Schools anatomy course after pandemic restrictions are lifted.

I think well go back to a more normal overall Med School structure at some point in the not-so-distant future, George said, but in regards to anatomy, its hard to predict when that will occur.

But theres certainly lessons we can learn from (COVID-19) about the curriculum and how to make it more efficient, George added.

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Alpert Medical School adapts first-year anatomy course to adhere to COVID-19 guidelines - The Brown Daily Herald

A Clinical Researcher’s Guide to Finding Purpose in Everything – Bethel University News

When Rachael Goldsmith 19 left Bethel, she had no idea what the first year after graduation would turn into. The biology major entered the workforce just weeks after returning from Guatemala, a semester she spent abroad to finish her Spanish minor, and the only thing she had officially decided was taking a break before heading to medical school.

She had no idea that shed eventually work three jobsas a medical scribe, barista, and clinical research intern. She had no idea shed be furloughed as a medical scribe due to the pandemic, or that a short time later shed be hired as a full-time research assistant for a COVID-19 treatment trial at Hennepin Healthcare Infectious Disease Research Department. She had no idea that shed be using her Spanish daily as she formed relationships with patients in the months-long trial.

Goldsmith ultimately had no idea shed love her job as a research assistant so much. Its really a dream come true, she says. I love this position. I wouldnt want to be spending my time doing anything else.

As the world waits for the development of an effective COVID-19 vaccine, Goldsmith and her team of fellow RAs are working on three different trials to treat the virus. One trial focuses on the inflammation accompanying COVID-19, while two other trials examine antibody treatments. She and her coworker work on treatment trials, and every other week, they rotate who enrolls patients in the trial and who collects and enters data into their system. They stay in touch with patients for two to three months as theyre in the hospital and then once they return home to see how they continue to respond to the medication.

Goldsmith had always been interested in clinical research, and that interest only grew during her time at Bethel. Through the C. Weldon Jones Memorial Research Scholarship, she studied breast cancer with Professor of Biology Paula Soneral. Because of this project, Goldsmith stepped right into the COVID-19 research processshe knew what questions to ask as well as how to work hard and efficiently. I think I had an advantage by understanding research as a whole, Goldsmith says. I was well-prepared to do a lot of work, and Bethels arduous biology and chemistry classes helped me understand the foundations of science really well.

Bethel also shaped Goldsmiths perspective of treating patients as human beings first rather than focusing on their role in a clinical study. Especially as she interacts with people who have been diagnosed with COVID-19, she does her best to be gentle and a comfort to those in isolation from their families. Knowing that somebody is comfortable talking to me about how theyre actually feeling and how theyre doing is something that Im super grateful for, Goldsmith says. I was well prepared for this by going to a college that emphasized people as whole and holy humans.

And part of honoring their humanity is meeting them where they are, and Goldsmith is thrilled to use Spanish to connect with patients as they cope with COVID-19. While she hadnt taken this position expecting to use her minor, she has been grateful and surprised by how frequently the opportunities arise, and now she uses Spanish daily as she meets patients, checks in on them during their hospital stay, and then when she calls to hear how theyre recovering. Because of her time in Guatemala and taking Languages and Cultures classes, she was well-prepared to utilize her skills to make the Spanish-speaking community in Minneapolis feel seen.

While Goldsmith invests in her jobwhich serves individuals both on a personal level as they receive treatment and on a global scale as researchers aim to produce an effective COVID-19 vaccineshes learning how to appreciate this season between graduating from Bethel and starting medical school. Although she initially felt restless as she navigated three jobs and wondered what would become of her gap year, she has since realized that each of those jobs helped her find her purpose. There is truly purpose in the everyday and the mundane and the journey, Goldsmith says. To people who graduate and feel like theyre not in their dream position right away, all things come in time. For the first year, you will get through it, especially if you have plans to go back to school in the future. Theres purpose to the whole pre-med track even if I dont go to medical school. Its all part of growing me into the human and the person I am supposed to be.

Goldsmiths future is full of countless opportunities. Some, like medical school, are part of her planwhile other dreams are wilder and still somewhat hazy, like owning a bakery in France. Ive always loved cooking and baking, and if I could own a bakerya fun little mix of American classics and French pastriesthat would be my ultimate dream. It would be kind of a stretch, and Id push myself to my limits, but over something a little less stressful, like croissants, rather than healthcare, Goldsmith laughs.

However, she is certainly in no rush to continue her education or move across the world, especially as she finds great fulfillment in her role right now. I dont know how much time Ill be taking off with this job, she says. I really, really like this period of life right now. Im just excited to take my time.

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Mayo takes over sponsorship of residency in Mankato – Mankato Free Press

MANKATO A long-standing family medicine residency program in Mankato will transition to a new educational affiliation in 2022, while continuing to bring up-and-coming physicians to the area.

The University of Minnesota medical school has sponsored the Mankato Family Medicine Residency Program since it started in the mid-1990s. Mayo Clinic Health Systems Eastridge clinic has been the site for the residents since 2005.

Eastridge will remain the site, but the program will switch to a Mayo Clinic School of Graduate Medical Education sponsorship in July 2022.

The move to bring the program under the Mayo Clinic umbrella will allow the health system to expand its educational capabilities in the southwest Minnesota region. The Mankato residency will join three other existing family medicine programs established in other regions in the health system.

The transition of the family medicine residency program further advances our Mayo Clinic Health System region into a three-shield organization that focuses on clinical care, research and education, said Dr. James Hebl, the health systems regional vice president, in a statement. The newly acquired residency program will allow us to pursue new and innovative educational opportunities while forming a deeper connection with our residents.

The partnership with the University of Minnesota is ending on a good note, said Dr. John McCabe, Mankatos residency program director.

Its just helpful to have one sponsoring institution and make it completely clear to all that our graduates are graduating from a Mayo program with training in a Mayo facility, McCabe said.

The University of Minnesotas release on what the transition will mean states itll lead to easier day-to-day functions because only one organization will be running it rather than two. The transition began with university residency faculty becoming Mayo Clinic employees in the summer.

The summer 2022 date is when the transition will be complete. Graduates after July 1, 2022 will then receive their completion certificate from Mayo Clinics graduate medical school.

The residency will remain a three-year program with five spots per year. More than 100 residents graduated from the program since it started, McCabe said, and the majority ended up working in southwest Minnesota or elsewhere in the state.

Physician shortages have long been a concern in rural areas, and residency programs can play an important role in retention. McCabe said the hope going forward will continue to be for residents to stay in the region once they finish the program.

Most of the time the majority of trainees end up in and around the region they train in, he said. That was one of the reasons the university had a program down here for such a long time.

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Research nets American Heart Association award for third-year OUWB med student – News at OU

A third-year OUWB medical student has been recognized by the American Heart Association for his research into the use of potentially life-saving equipment and training in K-12 schools.

M3 Eddie Ford received the Young Investigator Award from the American Heart Association as lead author on Characterizing Impact of State Legislation on Cardiac Arrest Outcomes at K-12 Schools.

The study sought to determine the effectiveness of state-level legislation requiring placement of automated external defibrillators (AEDs) in schools, along with CPR training and development of emergency response plans (EAPs).

Ford received the award in conjunction with the American Heart Associations Resuscitation Science Symposium 2020, a virtual event held Nov. 14-16.

The best thing about being a teacher is to have smart, motivated students, who work hard, ask good questions, and bring enthusiasm to a project such as this one, said Robert Swor, D.O., professor of emergency medicine, OUWB.

Ford is extremely grateful to receive the award.

There were a lot of people who helped with the project so it does feel really nice to have the hard work weve done validated, he said. Hopefully, this will help bring a better spotlight on these issues.

Researching cardiac arrest incidents

Ford worked as an EMT for two years before he began medical school, and after he earned a bachelors degree from University of Michigan.

With that background in emergency medicine, Ford became interested in the research project involving cardiac arrest at K-12 schools during an internship between his first and second years in medical school.

Ford said the study was very unique and that the research team involved knew of only one other project somewhat similar in scope.

In short, the study looked at out-of-hospital cardiac arrest survival rates involving the use of AED and/or CPR, specifically in the K-12 setting.

Further, the study examined the existence of laws regarding AED/CPR in all 50 states, a process that required Ford to spend many hours of research in Oakland Countys law library in Pontiac.

The study found that the majority of out-of-hospital cardiac arrests in K-12 settings typically involve an adult needing the life-saving techniques, though Ford notes that when a student is involved it tends to draw more attention in the media.

For example, the study looked at 314 cases of in-school cardiac arrests in 2017 and 2018 (based on data from the National EMS Information System). The average age for those cases was 46.7 and almost 80 percent were more than 18 years old.

Further, Ford said the most significant finding from the study was that there was no increase in bystander CPR or AED placement in states with legislation.

Essentially, he said, findings from the study highlight the importance of non-legislative initiatives, such as grassroots education efforts, which can be found throughout the country.

A great deal of heart

Ford learned of the award when he received a congratulatory letter in October from Benjamin Abella, M.D., co-chair, Resuscitation Science Symposium and professor and vice chair for Research, Department of Emergency Medicine, University of Pennsylvania.

The Young Investigator Awards are chosen based on the priority score of your submitted abstract, which scored very highly when reviewed by our seasoned abstract reviewer group, he wrote.

Swor is listed as a co-author on the study along with Patrick Karabon, biostatistician, OUWB, N. Clay Mann, Ph.D., University of Utah School of Medicine, and Monica Goble, M.D., C.S. Mott Childrens Hospital.

Swor said Ford was extraordinarily deserving of the AHA Young Investigator award, and I was thrilled to hear that he was a recipient this year.

Eddie was a joy to work with on this project, put a great deal of heart into the project, and did a great job following up to bring the abstract to fruition, said Swor.

For more information, contact Andrew Dietderich, marketing writer, OUWB, atadietderich@oakland.edu.

To request an interview, visit the OUWB Communications & Marketingwebpage.

NOTICE: Except where otherwise noted, all articles are published under aCreative Commons Attribution 3.0 license. You are free to copy, distribute, adapt, transmit, or make commercial use of this work as long as you attribute Oakland University William Beaumont School of Medicine as the original creator and include a link to this article.

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College Town: UMass Medical School hires vice chancellor for diversity and inclusion – Worcester Telegram

Scott O'Connell|Telegram & Gazette

WORCESTER UMass Medical School recently announced it has hired Marlina Duncan as vice chancellor for diversity and inclusion.

Duncan is currently the assistant vice president of academic diversity at Brown University, as well as associate dean of diversity initiatives in its Graduate School.

She previously worked on diversity programs at the Broad Institute in Cambridge.

In her current role, Dr. Duncan is a thought leader and trusted advisor to administrators, faculty and students, UMass Medical School Chancellor Michael Collins said, listing among her accomplishments the creation of a universitywide diversity and inclusion plan at Brown.

Duncan will assume her new post Dec. 28, according to the medical school. In that role, she will be responsible for overseeing the institutions diversity and inclusion office, and working with leaders across the medical schools programs and departments to ensure that diversity and inclusion remain at the forefront of the medical school, according to UMass.

QCC fundraiser

Citing greater than ever need among its students, Quinsigamond Community College has launched a fundraising campaign targeting alumni that will run until Dec. 1.

The GivingTuesdaygoal this year is to raise $30,000, in honor of the more than 30,000 alumni at Quinsigamond.

Money raised will go to programs and services on campus helping students in need, like the Student Emergency Fund, the on-campus food pantry, and various scholarships. Donors can specify where they want their donations to go, according to the college.

By donating to QCCs GivingTuesday campaign, you are helping a friend or a neighbor who may be one of the many front-line workers helping to keep us safe and our essential businesses operating, said Viviana M. Abreu-Hernandez, associate vice president for external affairs.

The need for monetary support has grown especially at Quinsigamond, according to the college, where students have lost jobs or had hours cut at their work during the COVID-19 pandemic. According to a survey of students receiving help from the Student Emergency Fund, for example, nearly half became unemployed this year, while 72% of those who are still working lost hours.

Many of those students werent able to be helped by special federal aid the college received this year because they were ineligible, the college said.

If all of our alumni and everyone in the community who knows a QCC alumnus were to make a donation, we would more than hit our goal, Abreu-Hernandez said. QCC is not a just college in Worcester, QCC is Worcesters college, and by supporting our students you are supporting the community.

Information about the fundraising campaign can be found at http://www.QCC.edu/QCCGives.

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Experimental hormone therapy may speed recovery for COVID patients – Minneapolis Star Tribune

DULUTH Every time the phone rang, it seemed to Kristine Smoley like more bad news about her husband, who contracted COVID-19 and was in a hospital intensive care unit on a ventilator because he couldnt breathe on his own.

Smoley was prepared for the worst when a nurse from Duluths Essentia Health called with hope albeit with risks and no solid evidence it would save her husband.

They asked if I wanted to consider signing off on an experimental treatment for him, Smoley said. A treatment that had never been done before.

Essentias Dr. Tim Rich and the University of Minnesota Medical Schools Dr. David Ingbar had studied for years whether a common thyroid hormone could be repurposed for the treatment of acute respiratory distress syndrome (ARDS), an often fatal type of lung failure. The doctors received federal approval late last year to test the therapy, so when COVID-19 caused a sudden surge in ARDS, they were ready for their first patient Smoleys husband, Bob Schlicht.

It was scary, Smoley said. But I dont know that I really had an option. Because the other option wasnt good.

The turnaround that followed was so remarkable that Rich and Ingbar have advanced their research unique for a regional medical provider in a world of urban and academic COVID-19 studies to a phase 2 U.S. Food and Drug Administration (FDA) study. The doctors have optimism about the impact their treatment could have amid the pandemic.

There has been a lot of highly technical science to understand this biology, but the elegance now is in its simplicity, said Rich, a pulmonologist. This is not a designer drug. This is something we know the lung needs and uses.

New therapies are needed against a pandemic that has caused 150,672 known infections, 10,334 hospitalizations and 2,475 deaths among Minnesotans. Only the antiviral remdesivir has received full FDA approval as a COVID-19 therapy for hospitalized patients, while treatments such as plasma infusions remain experimental and available only under emergency authorization.

Rich and Ingbar made a key discovery during the H1N1 pandemic of 2009, when families of those who died from influenza-related ARDS permitted autopsies. Rich found the victims lungs lacked T3, a thyroid hormone that would normally be detectable.

Ingbar said T3 reduces inflammation and coaxes epithelial cells in the lungs to absorb fluids which is vital for patients with ARDS.

A part of this acute lung injury with ARDS is the lungs get leaky, and they tend to fill with fluid, Ingbar said. That makes it really hard to get oxygen in or carbon dioxide out.

Schlicht was coughing and congested when Smoley dropped him at an emergency room in Grand Rapids on March 26, a few days after the retired couple cut cross-country travels short due to the spread of the novel coronavirus that causes COVID-19.

Schlicht, 68, was Itasca Countys first known positive case of COVID-19. Smoley watched medical staff garbed in full protective gear take her husband to an isolated room. He was transferred to Duluth within two days.

A few weeks later, Mary Ellen Evangelista found herself in a similar situation. Her brother, Tim White, was a corrections officer at the Moose Lake prison, where inmates and workers tested positive for COVID-19 in early April.

Evangelista, who lives in Georgia, urged White to call an ambulance after he spent a week getting sicker at home. He was placed on a ventilator in Duluth late that night because the virus led to ARDS.

Doctors told Evengelista that her 51-year-old brother might not survive and asked to try the thyroid hormone.

And every day, I just had a little more glimmer of hope, she said.

White spent more than a month in the Duluth hospital but has been back home since spring and is working to gain enough strength to return to work. Chest X-rays for months have shown healthy lungs.

This is really a much faster recovery than we see with typical ARDS, said Ingbar, noting that many survivors have lung scarring that can cause breathing problems for years and the need for supplemental oxygen.

White plans to visit his family in Georgia for the holidays. Evangelista choked up discussing the trip.

That hes going to be with us at Christmas was not a foregone conclusion back in April, she said.

Schlicht said he feels 100% healthy and has been helping build an event center near home for his sons upcoming wedding.

Each visit really puts in perspective how close we were to death, he said.

While the timing of recovery and abrupt reversal of symptoms suggest that T3 worked, doctors cant rule out that the men recovered due to other medical care.

The trial was paused for months following the treatment of Schlicht and White for a safety review, but Rich and Ingbar recently received the go-ahead to give the therapy to more patients in Duluth and plan to expand to three Twin Cities-area hospitals.

The next step to prove cause and effect is to recruit 68 patients with ARDS from COVID-19 or other causes for the FDA-approved study, and to compare 50 who receive supplemental T3 with 18 who receive standard care.

ARDS stems from a variety of causes, including heat, physical trauma or inhaled substances. Research showed that any such lung injury produces more of an enzyme that breaks down T3.

Theres a real local destruction of the hormone that explains why its concentration is so low, Ingbar said.

Doctors administer the hormone directly to a patients lungs through a breathing tube. That is a novel part of this study, as sick people have received thyroid hormones for years, but never straight into their lungs in this manner.

The Us Center for Translational Medicine is working to produce a patented powder T3 formulation. That inhaled or nebulized form would be cheaper and easier to administer, meaning more patients could receive it if it proves safe and effective.

Our hope is actually that this therapy should work for some other illnesses in addition to ARDS, Ingbar said. He and Rich may explore administering the treatment earlier to see if it prevents patients lungs from suffering distress.

Success of the ongoing study will be measured by whether supplemental T3 sops up enough lung fluid and allows for healthy blood oxygen levels. Rich said the overriding hope is not only survival but a return to life without chronic breathing problems and disabilities.

Any survival of ARDS, especially this COVID ARDS, is exciting, but its not enough to survive, Rich said. Its to not have the morbidity of a compromised lung for the rest of your life.

The recoveries of Schlicht and White will be featured in an upcoming medical journal. The two men, the first people in the world to receive this experimental treatment, met after Whites October checkup at the hospital where they spent so many sick days. They exchanged an elbow bump.

Im a very lucky man, White said, to be sitting here today.

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How COVID-19 threatens the careers of women in medicine – AAMC

Before she heads out to teach at the University of Cincinnati College of Medicine, Heather Christensen, PhD, preps for the at-home school day of her three children. After work, she makes dinner and does bedtime with the boys all under age 7 followed by work tasks until around 1 a.m.

But thats a lot better than early in the pandemic, when Christensen was educating her kids solo her husbands job cant be done from home making her math teacher, grammar expert, head chef, and school principal. Meanwhile, she was also figuring out how to redesign her medical school courses, which COVID-19 had driven online.

I had what felt almost like PTSD, with extreme fatigue and emotional exhaustion, she says. I couldnt keep doing it.

Now that Christensen has found other people to teach her children, the assistant professor is hoping to return to the research she set aside months ago research that is so crucial to her professional advancement.

Ive been incredibly frustrated, and my sentiments are repeated by almost every woman I speak to, from front-line COVID-19 workers to basic scientists to faculty members, she says. They all echo my frustration, but especially those with young kids.

As the pandemic upends so much in health care and society experts worry that COVID-19 could have dramatic effects on the careers of women in medicine.

Even before the pandemic, women physicians were earning 75 cents for every dollar their male counterparts made. Women also lag in leadership positions, comprising 25% of medical school professors and 18% of deans. And the ranks of women faculty of color have grown just 1 percentage point over the past decade. The research landscape is uneven as well, with women representing 41% of authors, a 2019 article reported.

Now, increased child care responsibilities, diminished opportunities for research and professional development, harassment in online settings, and hiring and promotional issues have women worried that their careers may take a hit for years to come.

Ive been incredibly frustrated, and my sentiments are repeated by almost every woman I speak to, from front-line COVID-19 workers to basic scientists to faculty members.

Heather Christensen, PhDUniversity of Cincinnati College of Medicine professor of medicine

While the full impact wont be known for months, women in medicine are already sounding the alarm. More than 20 women physicians and scientists recently warned that the pandemic could lead to a hemorrhaging of women from academia. In a recent survey, 46% of women medical students said they worry about COVID-19s effect on their careers, versus 36% of men. And a National Academies of Sciences, Engineering, and Medicine (NASEM) webinar noted that many academic jobs lost during the pandemic have been contract, nontenure-track positions jobs often held by women.

Gender inequities brought on by the pandemic must get addressed and soon, experts say. Its not just a social justice issue, argues Amy S. Gottlieb, MD, an associate dean at the University of Massachusetts Medical School-Baystate and the chair-elect of the AAMCs Group on Women in Medicine and Science steering committee. To thrive as a profession, we need to harness the talents of our entire workforce.

Theoretically, the pandemic could offer women physicians increased professional opportunities. Women have been at the forefront of efforts to track down much-needed personal protective equipment, for instance. Mostly, however, experts point to causes for concern.

Child care tops the list. Even before the pandemic, women physician-researchers did more parenting and domestic work than men in similar positions, totaling 8.5 additional hours per week.

Now women are doing even more at home, says Kimberly Templeton, MD, University of Kansas Medical Center professor and past president of the American Medical Womens Association. I worry that they will dramatically reduce their work hours or leave medicine entirely.

But experts also worry that COVID-19 threatens promotion prospects for women with no child care concerns. Thats in part because women get tapped more often to do less-valued tasks, such as writing patient education materials.

Then theres the concern that women have been stymied in publishing, which is so crucial to landing tenure. In fact, the portion of women lead authors in 2020 on COVID-19-related papers was 23% lower than their representation among lead authors in 2019.

It seemed like I kept hitting dead ends, and the men were getting the support. They often have large networks and a lot of resources.

Cynthia Derdeyn, PhDEmory Vaccine Center researcher and professor

Women in academic medicine bear a bigger load of teaching and patient care, notes Reshma Jagsi, MD, DPhil, senior author of the study and a professor at the University of Michigan Medical School. So the transition to virtual care and virtual teaching has created all these demands that are disproportionately falling to women, making it harder to publish.

Cynthia Derdeyn, PhD, had high hopes of contributing to COVID-19 research. After all, she runs a lab at Emory University that researches vaccines and infectious diseases. But, she says, it seemed like I kept hitting dead ends, and the men were getting the support. They often have large networks and a lot of resources.

Experts also fear that women are being hit hard in the online world, where the pandemic has driven so much work.

Women more than men tend to rely on nonverbal communication, and thats hard to do virtually, says Templeton. I worry about women being acknowledged and fully participating in virtual meetings, where its tough to read the room.

Templeton has particular concerns about women of color. She points to a recent webinar for women residency applicants, where many questions came from African American participants wondering how to wear their hair during virtual interviews. Its frustrating that with all that students are facing this year, they also have to worry about unconscious biases related to their appearance, she says.

In addition, women are losing out on vital networking opportunities as conferences move online, notes Eve Higginbotham, MD, vice dean for inclusion and diversity at the Perelman School of Medicine at the University of Pennsylvania. Women really need those sidebar conversations they get at in-person meetings, she says.

But most worrisome to Jagsi is the harassment that can harm women in the online world.

Since the pandemic in particular, weve seen a move toward using Twitter for communication, which leads to responses not just from the professional community, but from the public, she says. Twitter has opened up a number of my female colleagues to requests for dates, vulgar remarks, and really aggressive comments.

If you want your research papers to get noticed and cited, youd better have a Twitter presence, she says. But its the wild, wild west of what people will say to you.

Twitter has opened up a number of my female colleagues to requests for dates, vulgar remarks, and really aggressive comments.

Reshma Jagsi, MDUniversity of Michigan Medical School professor

Experts are working to address the ways the pandemic threatens progress for women in medicine. Here are some of their suggestions.

Step up for parents

Given increased and often unequal responsibilities at home, institutions need to provide women with flexible schedules and robust child care supports, experts argue.

Medical schools and teaching hospitals are trying to help. Indeed, 62% of institutions that provided child care before the pandemic expanded such services after it hit, according to a recent AAMC webinar.

Institutions that dont provide direct child care are assisting in other ways. The University of Florida College of Medicine connects staff and students to nearby nanny agencies, for example, and has negotiated discounts with local child care facilities.

At the University of California, San Francisco, leaders joined with the YMCA to create daylong learning camps in August. So far, some 100 children have attended, mostly from families of health care providers.

Shift promotion processes

To counter potential gender imbalances, institutions must rethink how they reward academic and organizational effort. Gottlieb encourages women to list pandemic-related service work on their CV and performance evaluations, for example.

But perhaps the biggest question is how to handle tenure clocks as COVID-19 hobbles credential-building work. Already, many institutions allow staff to request an extra year before coming up for tenure. Others have taken a much bolder approach: automatically stopping the clock for all candidates (with the option to opt out). Thats the case at Florida State University College of Medicine and Emory University School of Medicine, for example.

Templeton applauds the move. Women often have difficulty requesting something they need, she says. We may think that its just our personal issue, so we dont want to bother anybody. We too often dont feel empowered to speak up.

Actively level the playing field

Last month, leaders in internal medicine published suggestions for protecting women from the fallout of COVID-19. Among their recommendations was to proactively help women advance their careers.

Templeton points to one recent example: Women Orthopedic surgeons created a series of in-depth webinars for women medical students focusing on how best to handle virtual interviews for residency slots.

Also crucial this year is helping junior faculty build their careers through such supports as sponsoring them to present virtually at national conferences, Gottlieb says. At Michigan Medicine, for example, leaders have continued to fund conference registrations and professional society membership despite pandemic-related budgetary pressures.

You cant be what you cant see. So, if women leave medicine or they dont get promoted to leadership positions, Im afraid were at risk of losing future generations of women physicians.

Kimberly Templeton, MDUniversity of Kansas Medical Center professor

When leadership positions do open up, Gottlieb urges decision-makers to focus on equity, such as publicizing opportunities in places where diverse candidates will see them. Lets also make sure interview committees include women and individuals who are underrepresented in medicine, she says.

Higginbotham emphasizes another aspect of equitable hiring and promotion: training those in charge to avoid unconscious biases. At Penn Medicine, she notes, all 5,000 leaders have already received such training.

Pay attention

Finding solutions starts with identifying problems, so leaders advise monitoring how women in medicine are faring. Already, NASEM is exploring COVID-19s impact on women in medicine and science, looking at five domains, including their mental health.

In terms of medical schools and teaching hospitals, options include reaching out to women to assess their concerns. At Rosalind Franklin University of Medicine and Science, for example, the office of diversity arranged monthly calls for women faculty of color to discuss shared COVID-19-related issues and brainstorm possible solutions.

Gottlieb also urges closely monitoring areas where women tend to lag, like compensation. At the Medical College of Wisconsin, despite a hold on salary increases, leaders are continuing to monitor compensation to ensure equity down the road. Such attention is essential, Gottlieb notes, given that women physicians have one of the largest gender pay gaps in the entire U.S. labor market.

As they peer into the future, observers worry about the long-term fallout for women from COVID-19-related obstacles.

You cant be what you cant see, says Templeton. So, if women leave medicine or they dont get promoted to leadership positions, Im afraid were at risk of losing future generations of women physicians.

Meanwhile, Jagsi hopes that this years negative impact could actually lead to a positive turning point.

A year ago, we created a curve depicting womens progress as department chairs and deans. Based on that, we drew a forecast, which shows that if we dont change the curve, it will be 50 years before we reach parity. And now, because of COVID, it looks like the curve will actually change for the worse.

Maybe that fact will be so worrisome that people will unite to push the curve toward equity more quickly, Jagsi says. Thats my hope.

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How COVID-19 threatens the careers of women in medicine - AAMC

Former Surgeon General Vivek Murthy, MD, reflects on the power of our shared humanity – AAMC

Former United States Surgeon General Vivek Murthy, MD, traces his interest in the power of human connectionto his parents.

Murthys father grew up in dire poverty in a small farming village in India, often going without enough to eat. Against all odds, both of his parents attended graduate school and immigrated first to England, then to Canada, and later to the United States, where they started a medical practice.

It was through their deep commitment to the well-being of their patients that Murthy learned the power of authentic human connection.

Thats what keeps us whole, Murthy said during a session at Learn Serve Lead 2020: The Virtual Experience on Nov. 17. Thats what keeps us fulfilled and healthy. Its whats guided me throughout my life.

During the session, which centered around Murthys recent book, Together: The Healing Power of Human Connection in a Sometimes Lonely World, Murthy was also honored as the 2020 recipient of the Vilcek-Gold Award for Humanism in Healthcare, which recognizes a foreign-born individual who has had an extraordinary impact through their professional achievements. The session was facilitated by Mona Hanna-Attisha, MD, MPH, founder and director of the Michigan State University-Hurley Childrens Hospital Pediatric Public Health Initiativeand the 2019 recipient of the Vilcek-Gold Award.

Murthy recalled a story from his childhood when his parents woke him and his sister up in the middle of the night and strapped them into the car to drive to a trailer park. His parentshad just learned that one of their patients had passed away from cancer, and they wanted to be sure his wife wasnt grieving alone.

He remembers seeing his mother, dressed in a traditional Indian sari, wrapping her arms around the crying woman, whose family had lived in the United States for generations. In that moment, their commonalities outweighed their differences, he thought.

Its important, especially now as both a pandemic and a tense political climate threaten to pull people further apart, that everyone treat each other as fellow humans.

We all feel better when were giving and receiving love. We all feel worse when were living in fear, Murthy said. These are the things that actually unite us as human beings.

But it can be particularly challenging to put this into action, he added, as modern life makes it easy for people to create social silos only listening to and interacting with people who think the same way that they do.

How can we create opportunities for people in our country to actually get to know one another? Murthy said. You build a relationship first. Snarky posts on Twitter never change anyones mind.

The issues that plague Americans in general loneliness, emotional pain, and burnout are even more pronounced among physicians. This worries Murthy.

He emphasized the benefits for medical students and physicians of creating daily rituals that are grounding, even if theyjust thinkabout what they are grateful for while they brush their teeth.

Those anchors are very important for us, he said.

But the impetus for creating a better environment for health care workers doesnt lie solely with the individuals; it must start at the top.

Weve had a culture that tells us somehow that struggle is a sign of weakness, Murthy said. We have to create a culture where it is actually OK to be vulnerable.

He added that, to create real change, institutional leadership must reexamine their commitment to structures that place more emphasis on billing, correcting clinical deficiencies, and procuring funding than on improving patient care.

When was the last time you heard of somebody being promoted to tenure at your medical school because they were amazing at patient care and they build great relationships? Murthy said. The message that we send the newest members of our profession is that that stuff doesnt matter that what matters most is your publishing, your bringing in funding, thats what drives change in medicine. And the truth is thats not why most people got into this profession. We got in here to be a part of peoples lives, to spend time with patients, and to help people heal.

Improving the health of patients will also have to go beyond treating their ailments.

For clinicians, it can be disheartening to have a patient whose health and well-being is impacted by something that the clinician has little control over such as access to healthy food, housing, or other social determinants of health, Murthy said.

Thats why health systems should recognize the need to create community partnerships and give doctors the time and bandwidth to be engaged in making changes to the factors that impact their patients health.

We have to do this, not only for the well-being of our patients, but we have to do it to sustain our profession, because we cant endure more and more years of doctors burning out at the rates that they are, Murthy said. We have an opportunity to reflect, reevaluate, and change direction to build the kind of culture in medicine that we need and that our trainees, in particular, truly deserve.

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Former Surgeon General Vivek Murthy, MD, reflects on the power of our shared humanity - AAMC

Finch Therapeutics Presents Data from Its Positive PRISM3 Trial of CP101 in Recurrent C. difficile Infection at Two Leading Medical Conferences -…

Oct. 28, 2020 11:00 UTC

SOMERVILLE, Mass.--(BUSINESS WIRE)-- Finch Therapeutics Group, Inc. (Finch), a clinical-stage microbiome drug development company, reported today the presentation of results from the positive PRISM3 trial of CP101 for the prevention of recurrent C. difficile infection (CDI) at the United European Gastroenterology Week (UEGW) and the American College of Gastroenterology (ACG) Annual Scientific Meeting, two leading gastroenterology conferences held virtually this month. The data presented expand on the positive topline results previously reported from PRISM3, a randomized, placebo-controlled, multi-center, Phase 2 trial, which demonstrated that CP101 met the primary efficacy endpoint with a statistically significant improvement in the prevention of recurrent CDI compared to placebo.

The presented PRISM3 results show that CP101 resulted in a statistically significant and clinically meaningful improvement in the prevention of recurrent CDI when evaluated in a broad patient population, including participants enrolled after their first recurrence and participants enrolled with any guideline-approved CDI diagnostic method, said Colleen Kelly, MD, Associate Professor of Medicine at Warren Alpert Medical School of Brown University and a Principal Investigator in the PRISM3 trial at the Lifespan Physician Group Gastroenterology. Demonstrating positive results in this broad population is exciting because it provides compelling evidence to support the potential use of CP101 early in the disease cycle and increases the generalizability of the results to real-world clinical practice.

Highlights of the PRISM3 results shared at UEGW and ACG virtual conferences include:

We are enthusiastic that the PRISM3 results demonstrate that CP101 has the potential to fulfill the need for an oral drug that breaks the cycle of CDI recurrence early and prevents the debilitating effects of recurrent CDI on patients lives, said Zain Kassam, MD, MPH, Chief Medical Officer at Finch. Leveraging CP101s Breakthrough Therapy designation, we look forward to continuing to engage with the FDA on the next steps necessary to bring CP101 to patients suffering from recurrent CDI.

About CP101

CP101 is an investigational, orally administered microbiome drug that Finch is developing for conditions linked to microbiome dysfunction. With 42 billion doses of antibiotics administered globally each year, resulting in widespread damage to the microbiome, research suggests that microbiome dysfunction is associated with the pathogenesis of a wide range of serious medical conditions. CP101 is designed to deliver complete microbiome communities in orally administered, enteric release capsules. CP101 is rigorously tested and manufactured under Good Manufacturing Practice conditions. CP101 is in late-stage clinical development for the prevention of recurrent C. difficile infection. Finch plans to deploy CP101 to other conditions linked to microbiome disruption, starting with the evaluation of CP101 as a treatment for chronic hepatitis B.

About Finch Therapeutics

Finch Therapeutics is developing novel microbiome drugs to serve patients with serious unmet medical needs. Finchs Human-First Discovery platform enables reverse translation from clinical data to engineer the composition of the microbiome based on disease-modifying mechanisms. Finchs platform uniquely enables development of both complete microbiome communities and rationally selected consortia to restore microbiome functionality and resolve conditions driven by dysbiosis, or disruption of the microbiome. Finchs lead candidate CP101 is an investigational, orally administered microbiome drug with Fast Track and Breakthrough Therapy designation from the US Food and Drug Administration for the prevention of recurrent C. difficile infection. Finch is also developing FIN-211 for the treatment of children with autism spectrum disorder and CP101 for the treatment of chronic hepatitis B. Finch has a strategic partnership with Takeda Pharmaceuticals focused on the development of microbiome drugs for inflammatory bowel diseases.

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Finch Therapeutics Presents Data from Its Positive PRISM3 Trial of CP101 in Recurrent C. difficile Infection at Two Leading Medical Conferences -...

COVID proves better pay and housing are quickest ways to better health – Houston Chronicle

The best way to maximize your chances of surviving COVID-19 without hospitalization is to be healthy when you contract it.

Pre-existing conditions such as respiratory problems, vascular disease, obesity, and diabetes exacerbate the coronavirus health effects. Most of us know that so-called comorbidities raise the odds a person will end up hospitalized by the disease. And most of those conditions are preventable.

Personal fitness influences how well we tolerate most illnesses and injuries. Employers who provide health insurance know they can bring down costs by encouraging workers to take better care of themselves. But the best way to do that is not how most people might assume.

The land of the free is the land of the unhealthy, at least when compared to other societies with similar resources. The latest Global Burden of Disease Study reveals a nation where young children die at shockingly high rates, life expectancy is short, and disease-free years are too few.

TOMLINSONS TAKE: Hospitals gouge private health insurance to care for others

The mortality rate for mothers and infants in the United States is 6.5 per 1,000 births, compared to 4.9 in other wealthy countries. The number of years the average American lives in good health is 65.5 and getting shorter due to rising rates of obesity and heart disease. The average Japanese enjoys 20 additional good years.

While other countries have seen dramatic increases in life expectancy, Americans have seen no improvement in a decade.

Americans made up more than half of the worlds overdose deaths in 2019. U.S. doctors over-prescribe opioids, rehab programs do not use the best methods, and street drugs are laced with dangerous additives. But drug abuse and chronic disease are symptoms of larger problems that go beyond medical intervention.

Research has shown that social, economic and behavioral factors are far more critical than medical conditions in determining our quality and length of life, something reinforced by the latest Global Burden of Disease Study published in The Lancet medical journal this month.

An exclusive focus on health care is a mistake, the editors wrote. Health is created from a broader prospectus that includes the quality of education (primary to tertiary), economic growth, gender equality, and migration policy.

Limited access to fresh food, smoking and drugs, moldy housing and lack of transportation damage more peoples health than genetics. Life expectancies in Texass wealthiest census tracts are 17 years longer than those in the most impoverished areas, the National Center for Health Statistics found.

Research shows 80 percent to 90 percent of a persons health is determined by non-medical factors.

More than 88 percent of companies that employ more than 200 workers include so-called wellness programs with their health insurance, according to the Kaiser Family Foundation. But since most of the incentives focus on medical conditions, not social issues, wellness programs have shown limited benefits, according to most studies.

The problem is health insurers and employers are reluctant to address the so-called social determinants of health. They do not want to pay higher wages, remediate mold in homes, cover taxi fare to quality grocery stores, subsidize rent in better neighborhoods or provide access to better schools.

The Houston-based Episcopal Health Foundation gave $2.6 million to the Dell Medical School in Austin to research how non-medical issues affect public health in Texas. Experts hope to determine exactly how best to save money on health spending by raising living standards so that everyone benefits.

Of all the factors that determine whether or not a person or population is healthy, medical care is actually a pretty small piece, Elena Marks, the foundations CEO, told a Rice University webinar.

In 2018, the U.S. spent $3.5 trillion on health care; only 2.6 percent was spent on social factors, according to federal data. European countries that spend twice as much on social services have far healthier populations.

TOMLINSONS TAKE: The economy will recover faster if Texans contain COVID

The consequences for employer-based health programs could be dramatic. Could paying higher wages to improve a workers living standard result in lower health care costs and less missed work? Might a weekly farmers market with cooking lessons lead to fewer hospitalizations and money saved?

When it comes to COVID-19, social factors are driving the pandemic, with poor people who live in substandard housing without access to healthy food and routine health care getting the sickest. If we address those issues beforehand, no pandemic or any other crisis would cause as much economic damage.

We saw this during Hurricane Harvey and now were seeing it during COVID. Its time to do something about it, Marks said.

Ultimately, the best way to improve our collective health is to lift people out of poverty, provide them with a quality education and ensure an equitable stake in the nations health. Prevention is always cheaper than a cure.

Tomlinson writes commentary about business, economics and policy.

twitter.com/cltomlinson

chris.tomlinson@chron.com

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COVID proves better pay and housing are quickest ways to better health - Houston Chronicle

Renown, UNR Med working to finalize new ‘destination health’ partnership – Northern Nevada Business Weekly

RENO, Nev. For 50 years, Renown Health and the University of Nevada, Reno School of Medicine have had a long history of working together to improve healthcare in Northern Nevada.

This year, the notorious 2020, when an unprecedented pandemic hit every corner of the globe and caused more than 1 million deaths, Renown and UNR Med recognized they could better serve Reno-Sparks if they did more than occasionally collaborate.

Were now at a pivotal point where we believe we could advance the work that were doing together, Dr. Anthony Slonim, CEO of Renown, said in a phone interview with the NNBW. And well be better if we advance it together for the benefit of the community.

With that, in late August, Renown Health and UNR Med announced their intent to develop a long-term partnership that both entities say will greatly enhance the states medical education system while expanding clinical research capacity across greater Northern Nevada.

Our strategic plan that we created with our board calls into execution the focus on what were calling destination health programming, Slonim explained. We want to be the place where through amazing clinical care and service we are keeping people who need to be cared for in our community, right at home.

And you cant do that if you dont have a medical school with you. You have to have the research and the training capabilities because it makes everybody on the team better. It allows you to recruit better, it allows you to educate better. It raises the bar for everybody.

Slonim pointed to Renown and UNR Meds previous collaboration in pediatrics as an example of what high-level partnerships can produce. UNR Med doctors and residents provide care in general pediatrics (and a host of other services) at Renown Childrens Hospital, which opened in 2009, the first and only childrens hospital in the region.

Were doing the same thing in other services cardiovascular care, cancer care, neuroscience care as we continue to demonstrate that world-class kind of care, Slonim noted.

Bringing those high-level services will not be possible without the school of medicine developing new residency training programs, fellowships and clinical research studies, said UNR Med Dean Dr. Thomas Schwenk andaccess to Renowns large health system would enable UNR Med to do just that.

It opens a host of possibilities, he told the NNBW. And all of those feed back to increasing the access to care and increasing the high-level nature (of care) and to develop care that does not now exist in the community.

Both organizations in early September executed a Letter of Intent for their partnership, said Schwenk, who later presented it to the Nevada System of Higher Education (NSHE) Board of Regents, which gave its stamp of approval.

Currently, the entities are in a due diligence phase of laying out and examining the partnerships governances, financial flow and operational structure, Schwenk said, as well as culture, employment, human resources and other details.

Once ironed out, a final agreement between UNR Med and Renown will be taken to their boards for approval in December or January.

If approved, implementation details would be fine-tuned through the first half of 2021, with the goal of officially launching a partnership by July 1, Schwenk he said.

Were creating a new entity, he said. Its not just us joining Renown or Renown joining the school. Its actually a new integration of what you might call an academic health system or a teaching-and-research health system. What we get to do, if this goes through, is have a much larger influence on the care and the community.

The integration, Schwenk said, would make Reno-Sparks an even more attractive area to companies considering relocating or expanding to the region.

This is what new businesses want to see when they move into the community, and this is what employees want to see when they are recruited to the community, he said. And so I think, ultimately, this is about the quality of life, the quality of the business climate, and the overall economic success of the community. And healthcare is a major driver of that.

According to Renown and UNR Med, their planned integration resembles other partnerships such as Yale New Haven Health System, Penn Medicine, RWJ-Barnabas-Rutgers and the Washington University-Barnes Jewish Health System in St. Louis.

I think the world of healthcare now is built on collaboration and partnership to improve the way that weve historically delivered on care, Slonim said. So, were very excited to partner with the medical school. We think it will not only make the school better, it will make Renown better. And together, we think we can bring a higher level of care to the community as we move forward.

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Renown, UNR Med working to finalize new 'destination health' partnership - Northern Nevada Business Weekly

Abstracts now accepted for Medical Education Research and Innovation Conference – The South End

The Wayne State University School of Medicine will hold its second annual Medical Education Research and Innovation Conference on Dec. 8 to showcase completed and in-progress medical education research and innovation projects conducted by students, residents, staff and faculty.

Last years inaugural conference saw more than 80 posters and oral presentations submitted, said Jason Booza, Ph.D., assistant dean of Continuous Quality Improvement and Compliance.

The virtual conference will take place from 2 to 6 p.m.

Featured speakers include Holly Gooding, M.D., associate professor of Pediatrics at the Emory University School of Medicine and co-director of the Harvard Macy Program for Educators in the Health Professions; and Anna Cianciolo, Ph.D., associate professor of Medical Education at the Southern Illinois University School of Medicine and editor in chief of Teaching and Learning in Medicine.

Submit abstracts for a completed or in-progress project using the links below:

Medical Education Research:Research related to the learning process that occurs within a medical education setting. Topics include, but are not limited to, learner characteristics, optimizing the learning process, assessment and evaluation, professional development, instruction design, technology in the learning environment and wellbeing. Research at any level (undergraduate, graduate, practitioner, faculty) of medical education is welcome. Medical education research can also include quality improvement projects.

Medical Education Innovation: Innovative curricula that address a current issue within medical education. The innovation should be based on learning principles and be designed to meet a specific need. Examples include, but are not limited to, health and wellness, quality improvement, patient safety, interprofessional education and service learning. You can submit a project as Works in Progress," which includes research and innovation projects that are being developed or have yet to be completed. In place of results in the abstracts, please submit your analysis plan and lessons learned thus far.

To attend the conference, RSVP here.

Contact Dr. Booza @ jbooza@med.wayne.edu for additional information.

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Abstracts now accepted for Medical Education Research and Innovation Conference - The South End

Couples share heart disease risk factors and behaviors – Harvard Gazette

Risk factors for heart health, such as smoking, unhealthy diets and minimal physical activity, may seem personal, but for people who are married or in a domestic partnership, the behavior patterns of one person may be strongly linked to the patterns of the other.

A new study led by investigators from Harvard-affiliatedBrigham and Womens Hospitalassessed cardiovascular risk factors and behaviors of more than 5,000 couples who took part in an employee wellness program offered by Quest Diagnostics. The team used several metrics to classify people as having ideal or non-ideal risk factors and behaviors, finding that in 79 percent of couples, both people fell into the non-ideal category for cardiovascular health, with most sharing unhealthy diets and getting inadequate exercise. The findings point out the potential importance of addressing healthy behaviors for both people in a relationship. Results are published inJAMA Network Open.

We know a lot about cardiovascular risk factors for individuals but not for couples, said corresponding authorSamia Mora of the Brigham Divisions of Preventive Medicine and Cardiovascular Medicine. We expected to see some shared risk factors, but it was a surprise to see that the vast majority of couples were in a non-ideal category for overall cardiovascular health.

Mora and colleagues examined data from Quest Diagnostics, which offered a voluntary health assessment program to its employees. Researchers analyzed data from 5,364 couples (10,728 individuals) who joined the program between October 2014 and August 2015. The researchers determined whether each individual was in the ideal, intermediate, or poor category for each of the American Heart Association-defined Lifes Simple 7 (LS7) risk factors and behaviors. The LS7 include smoking status, body mass index, physical activity, healthy diet score, total cholesterol, blood pressure and fasting glucose. The team also gave each participant an overall cardiovascular (CV) health score. Data were collected from questionnaires, examinations and laboratory tests.

When examined individually, more than half of the participants were in the ideal category for three LS7 risk factors and behaviors: smoking status (never smoked), total cholesterol (<200 mg/dL), and fasting glucose (<100 mg/dL, Table 2). But more than a quarter of the individuals were in the poor categories for BMI, physical activity, and CV health score. Only 12 percent of individuals were in the ideal category for CV health score.

Rather than thinking about interventions for individuals, it may be helpful to think about interventions for couples or whole families.

Samia Mora, Brigham and Women's Hospital

When both people in the couple were considered together, more than half of couples shared all LS7 risk factors and behaviors as well as CV health score.When one member of a couple was in the ideal category, the second member was more likely to be in the ideal category for all factors except for total cholesterol. But 79 percent of couples were both in the non-ideal category for CV health score, largely driven by unhealthy diet and inadequate exercise.

The team did find that when one partner had quit smoking, lost weight, increased their physical activity or improved their diet, the other partner was more likely to have done so. But over the five-year study period, the health of couples, risk factors and behavior patterns remained relatively unchanged overall. Apart from modest changes in blood pressure and fasting glucose, the team found no significant changes in factors.

The authors note that some of the data in the study comes from self-reporting, which can be inaccurate, and that the longest duration for follow up was five years. The study only examined data for employees who chose to participate in the companys wellness program, but it was a diverse population. The team found some variation by ethnicity, socioeconomic status, and geographic location.

Our data suggest that risk factors and behaviors track together for couples, said Mora, who is an associate professor of medicine at Harvard Medical School. Rather than thinking about interventions for individuals, it may be helpful to think about interventions for couples or whole families. And its important for people to think about how their health and behaviors may influence the health of the person(s) they are living with. Improving our own health may help others.

Mora has served as a consultant for Quest Diagnostics for work outside the current study. Four co-authors are employees of Quest Diagnostics.

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Couples share heart disease risk factors and behaviors - Harvard Gazette

Tracking the Spread – Harvard Medical School

This article is part of Harvard Medical Schoolscontinuing coverageof medicine, biomedical research, medical education and policy related to the SARS-CoV-2 pandemic and the disease COVID-19.

Recent U.S. outbreaks of COVID-19 have been detected following in-person attendance atfootball games, which have the potential to become super spreader events, according to research using artificial intelligence tools.

Using an AI-basedCOVID-19 Outbreak Detection Tool, researchers atMassachusetts General Hospital, Harvard Medical School,Georgia Tech and Boston Medical Center noted that 17 of 33 NFL and NCAA games played by late September with fans in attendance were located in counties with rising COVID-19 cases at the time of the game.

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One of those games, the Denver Broncos vs. the Tampa Bay Buccaneers at Empower Field in Denver, took place on Sept. 27.

Our model indicated that the county where the game was played had a COVID-19 doubling time of two to three weeks and nearly 700 total new cases in the county during the week before the game was played, said Jagpreet Chhatwal, assistant professor of radiology at HMS and associate director of the MGH Institute for Technology Assessment.

This example highlights how officials may use this tool to make informed decisions on the safety of future in-person attendance by taking into account both past week trends as well as predicted trends, Chhatwal said.

Because the National Football League and the National Collegiate Athletic Association have made the decision to play games amid the ongoing COVID-19 pandemic, the researchers have extended the use of the COVID-19 Outbreak Detection Toolto incorporate NFL and NCAA football games. The model can help public officials and team owners in their decision-making regarding in-person attendance.

The tool provides predicted trends such asthe COVID-19 doubling time, or the number of days it takes for COVID-19 cases to double, andhow fast COVID-19 cases are increasing in counties with NFL or NCAA stadiums that have hosted games or might host games in the future.

The investigators will add information on the attendance numbers for each game, which can indicate the potential risk of infection spread in surrounding communities.

Public health officials can work alongside team executives to continuously assess the situation of the county where the games are being played, along with neighboring counties, to guide their decision-making with respect to when to allow fans back in the stadiums, whether to allow fans from other counties and states to attend and when to discontinue fan attendance, said Asmae Toumi, a data analyst at the MGH Institute for Technology Assessment.

Officials can also view the individual stadium capacity as well as the total stadium capacity of the county or state, which can inform decisions on how many fans can attend, Toumi said.

Collaborators include Zhaowei She, Zilong Wang and Turgay Ayer from Georgia Tech; Madeline Adee and Mary Ann Ladd from Mass General and Benjamin Linas from Boston Medical Center.

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Tracking the Spread - Harvard Medical School

Harvard Medical School Professor Lisa Iezzoni to speak at URI Oct. 27 on health care disparities and disability – URI Today

KINGSTON, R.I. October 16, 2020 Lisa Iezzoni, M.D., a professor of medicine at Harvard Medical School, will speak Tuesday, Oct. 27, as part of the University of Rhode Island Honors Colloquium, Challenging Expectations: Disability in the 21st Century.

Iezzoni, who is based at the Health Policy Research Center, Mongan Institute of Massachusetts General Hospital, will give the online lecture, Healthcare Disparities for People with Disability at 7 p.m.

The link to the lecture can be found on the day of the event in the colloquium schedule, next to Iezzonis name. The lecture is free and open to the public.

Her early career focused on risk adjustment methods for costs and clinical outcomes and assessing quality of care. She wrote and edited Risk Adjustment for Measuring Health Care Outcomes, now in its fourth edition.

Iezzoni has conducted numerous studies for the Agency for Healthcare Research and Quality, National Institutes of Health, the Medicare agency and private foundations. Since 1998, her research has focused on improving the experiences of and health care quality for adults with disabilities.

Her book, When Walking Fails, was published in 2003, and More Than Ramps: A Guide to Improving Health Care Quality and Access for People with Disabilities, co-authored with Bonnie L. ODay, appeared in 2006.

Iezzoni also spends much of her time advocating for people with disabilities. Representing the Boston Center for Independent Living, she chaired the Medical Diagnostic Equipment Accessibility Standards Advisory Committee for the U.S. Access Board from 2012 through 2013. Iezzoni is a member of the National Academy of Medicine in the National Academy of Sciences.

Gianna Carderelli, a University of Rhode public relations major and intern in its Department of Marketing and Communications, wrote this press release.

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Harvard Medical School Professor Lisa Iezzoni to speak at URI Oct. 27 on health care disparities and disability - URI Today

The Horror of Medical School Captured on Film – Medscape

This Q&A has been edited for clarity.

What if the figurative terror faced by medical students was turned into literal, tangible horror?

Phillip Anjum, a third-year medical student at The Ohio State University College of Medicine in Columbus, Ohio, wanted to find a new way to demonstrate the stress, anxiety, and isolation experienced by medical trainees. Drawing upon his background in film, he made History of Present Illness, a horror short that tackles med student burnout in a more visceral way.

We spoke with Anjum about what he hopes school administrators and others in medicine take from his project, as well as his experience of balancing filmmaking with becoming a doctor.

The first 2 years of medical school are rough. I don't think anyone has a smooth ride. I wanted to represent that in a way that was unique and also not in a way that is constantly sugarcoated by medical schools. I think all medical schools suggest that, when you come there, you are taken care of. You have your classmates and your advisors, and everyone is supporting you and you get through it. But when you actually get there, you realize that medical training in general is a very isolating experience.

I think there's no way that you can get around that, and I think the sooner that you realize that and develop ways to deal with the stress and anxiety, the sooner you can be successful in your training.

We all feel lonely. I think there's a lot of fear of physicians expressing their insecurities, expressing their shortcomings and saying, "I'm stressed. I'm depressed." I think I just wanted to get that out there through the film and say that everyone is struggling in some aspect. That's the biggest thing I wanted to capture.

Writer/director Phillip Anjum and actress Caitlin Wilson discuss a scene from the film.

Yes, that part always made me nervous! I think it's important to be critical of the administration, of your teachers, at times. I have had advisors who I love, people that I can talk to. That's not the point. The point is that especially with the COVID pandemic and with the ongoing protests there is definitely a feeling that support from the administration is lacking at certain times when we need it the most.

I wanted to make something that was critical and more than just saying something in an email. I think emails and words get brushed aside a lot more easily than a video piece that's speaking to someone emotionally. I wanted to say, "This is what it feels like. This is what it looks like when you're not there for a medical student."

I think, from the students, it's gotten pretty universal praise. Every single medical student or resident who has watched it has said that they have felt pretty similar at times. I've also gotten a lot of comments that every medical school seems to have a scary basement, which is a little bit unnerving...

In terms of the administration, I've kind of avoided spreading it too far, just because of the fear that it is critical. I've gotten a bit more measured responses from administration. I think there's a hesitancy from students to produce anything that's critical.

Medical schools could do a much better job of simply taking what the students say and then implementing that. I think a lot of our classmates feel that administration just doesn't listen. They say that they'll do something but then they don't actually do it. I would say more follow-through.

Actors Stephen Manos and Caitlin Wilson in a scene from History of Present Illness.

I do have a bigger project on the way. It's about the fourth year of medical school. It's almost the exact opposite of this short. History of Present Illness is a horror film. It's about feeling isolated. It's about feeling like you are on your own.

This other film, tentatively called A Place For Us, is about two medical students who are about to graduate. They're looking back on the people and the doctors that they have become. That one is more of a drama. It comes from a place of strength. It's meant to be a foil to History of Present Illness.

I think, for all doctors and providers, it's so much more important nowadays to have an awareness of your media presence. People need to be aware of how you can use a photo on Instagram or a TikTok video to your advantage in terms of providing clinical care, clinical information, and also just good PR. I mean, we've seen throughout this pandemic I won't go into specifics about anything political but there's definitely been a lot of back-and-forth from providers and non-providers in terms of advice about the coronavirus. I think that with better PR and better communication, you can swing what people listen to.

I feel like I'm urged to choose something medical, but... I'd recommend two films that really influenced me. One is Moonlight, which I really just love. In general, whether you're a provider or just whoever you are, I recommend that movie. It covers a lot of topics, like racial disparities, disadvantaged populations, healthcare insecurity, drugs, and just everything. It's a beautiful film.

Speaking of beautiful, the other one that I really love is the movie Biutiful. Both of those films are about men who struggle with who they are and what they want to do with their lives. I think that's something that speaks to me.

Editor's note: History of Present Illness was first published on in-Training.

Ryan Syrek, MA, is the section editor for medical student and resident content at Medscape.

Phillip Anjum is a third-year medical student at The Ohio State University College of Medicine in Columbus, Ohio. He enjoys making films and spending time with his wife.

For more news follow Medscape on Facebook, Twitter, Instagram, and YouTube

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The Horror of Medical School Captured on Film - Medscape

Birth of Baby Brother Ignites Medical Student’s Passion To Heal – UNLV NewsCenter

Now in her second year at the UNLV School of Medicine, Paris Collier vividly remembers a day when she was just 4 years old, a day that started her on the path to becoming a physician.

I pressed my forehead against the cool glass, attempting to get a better look. My brother lay in his incubator, no bigger than my fathers hand, with tubes and wires covering his tiny body, she said. While the scene might create unease for most, for the first time since his birth, I felt a sense of relief. For weeks, my brother had been in the neonatal intensive care unit (NICU) fighting for his life as my family and I worried at home. Even at such a young age, I understood the situation was dire. This was the first moment I ever got to lay eyes on my newborn brother.

Though children were not allowed in the NICU, a nurse had agreed to let the little girl look at her brother for five minutes through a window.

My brother was born at just 27 weeks and spent two months confined to the NICU. I was so proud to be a big sister, but I felt helpless and scared. Will my brother live? Why are my parents crying? Why cant he breathe on his own? I wanted to know why and I wanted to help. Reflecting now, it was this moment that set me on a journey to an interest in medicine.

Today, her brother William, who was born with a number of allergies and asthma, is in college. While Collier describes him as a wonderful young man, she said that during the COVID-19 pandemic, he must be especially careful because of his underlying health conditions. He and my mom are staying home quite a bit.

It wasnt just that brief glimpse of her brother in the NICU that steered her toward a career in medicine. Going to appointment after appointment with him made me want to learn about the human body. I watched as a doctor could calm my mothers nerves or make my brother smile. I could feel the care and concern the physicians had, not only for the patient, but for our entire family. Throughout my schooling, I frequently pursued science opportunities to increase my knowledge. This ultimately led me to want to pursue a career in medicine.

A magna cum laude graduate of UNR, Collier majored in both biology and Spanish. She credits her love for the foreign language to both her grandfather and to teachers she had in grades K-12. My grandfather speaks Spanish fluently and was even a Spanish teacher before becoming a lawyer. I was able to start picking up the language from a young age and continued to study it in school. I saw an opportunity to serve a greater community by learning another language. I hope that my experience with the language and culture will help me to be a better physician for my patients.

During her sophomore year of college, Collier studied abroad in Costa Rica, shadowing at a local hospital in the town of San Ramon. While assisting with physical therapy exercises, watching live births, and observing several different surgical specialties, she was able to directly interact with patients and local health care workers. My experience was amazing, to say the least.

That experience in Costa Rica, which offers universal health care to its citizens, reinforced her belief that health care should be a right. I was privileged to have access to health care throughout my life, but for some people in our country that is not the case. I hope that as a future physician I can use my voice, my vote, and my platform to help move our health care system towards a better future.

Collier her mother is a sales rep for a pharmaceutical company and her father works in the tech industry says she chose to attend the UNLV School of Medicine because she connected with the mission statement of the school. Nevada has been my home for many years and the UNLV School of Medicine is fiercely devoted to serving the state and especially underrepresented groups.

Though she misses much of the in-person study at the medical school because of COVID-19, Collier said the emphasis on virtual technology could translate to better care for patients. I think one positive thing that may come out of this pandemic is an emphasis on telemedicine. This can make providers more accessible to their patients. Transportation to appointments can be a huge barrier for patients. In the future, more providers will now be able to assess patients without having them come in person.

The emphasis on volunteer work during medical school is something Collier has long embraced. Prior to the COVID-19 outbreak, she was very active at Squires Elementary School, helping students with homework and art and outdoor activities. Volunteering at Squires was always the best part of my week. Her volunteerism was particularly on display during her undergraduate years, as she helped raise $60,000 for Renown Hospital in Reno the hospital she credits with saving her brothers life by organizing dance marathon fundraisers.

Collier, who was elected treasurer of her medical school class, is frequently asked how she was named Paris.

My parents said they wanted to give me a somewhat unique name. They dreamed of getting to travel the world someday. They got the idea to look at an atlas for names. They fell in love with the name Paris and the rest was history.

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Birth of Baby Brother Ignites Medical Student's Passion To Heal - UNLV NewsCenter