NEI researchers link age-related DNA modifications to susceptibility to eye disease – National Institutes of Health

News Release

Tuesday, April 21, 2020

Findings point to targeting epigenome as a potential therapeutic strategy.

National Eye Institute (NEI) researchers profiling epigenomic changes in light-sensing mouse photoreceptors have a clearer picture of how age-related eye diseases may be linked to age-related changes in the regulation of gene expression. The findings, published online April 21 in Cell Reports, suggest that the epigenome could be targeted as a therapeutic strategy to prevent leading causes of vision loss, such as age-related macular degeneration (AMD). NEI is part of the National Institutes of Health.

Our study elucidates the molecular changes and biological pathways linked with aging of rod photoreceptors, light-sensing cells of the retina. Future investigations can now move forward to study how we can prevent or delay vision loss in aging and hopefully reduce the risk of associated neurodegeneration said the studys lead investigator, Anand Swaroop, Ph.D., senior investigator and chief of the NEI Neurobiology, Neurodegeneration, and Repair Laboratory.

Each organism is born with a genome, a library of genes that control all the bodys cellular and tissue functions. Expression of those genes when information stored in DNA is converted into instructions for making proteins or other molecules is modulated and maintained by the organisms epigenome. The epigenome tags the DNA code to modify gene expression in ways that can be favorable and unfavorable for survival.

As it turns out, that interplay between the genome and the epigenome evolves as the organism ages. Scientists therefore study epigenomic DNA modifications for clues about why certain diseases develop with advancing age.

To explore how such DNA modifications might influence visual function as we age, Swaroops team performed whole genome sequencing of DNA methylation changes in mouse rod photoreceptors at four separate stages over the animals lifetime. DNA methylation is an epigenetic mechanism essential for normal cell development and differentiation, and is also associated with aging and the formation of cancers. When present, DNA methylation generally represses gene expression.

The sequencing was performed at ages three months (young), 12 months (middle-aged), and 18 and 24 months (older). The average lifespan of a mouse is about two years.

Rod photoreceptors are the predominant type of cell in the retina, the light-sensing tissue at the back of the eye. Rod photoreceptors enable dim-light vision, and are critical for the survival of cone photoreceptors that enable daylight and color vision. Rod dysfunction is common in older human adults and can be an early warning sign of AMD and other retinal degenerative diseases.

The researchers identified 2,054 differentially methylated regions across the four mouse age groups, that is, genomic regions with differences in DNA methylation.

We know that DNA methylation changes are strongly associated with biological age, but prior to this study we had limited understanding of how these alterations correlated with cellular function, Swaroop said. This is the first study to look at DNA methylation changes as animals age. Very few studies have looked at DNA methylation changes in people with AMD, a leading cause of vision loss in people age 50 and older, which can progress even when vision loss is undetectable.

The researchers then analyzed the differentially methylated regions with RNA sequencing data to look more closely at how the mouse genes were transcribing proteins differently in the retina as the animals aged.

Those analyses uncovered distinct shifts in how the genes produced proteins relevant to energy metabolism, mitochondria function, and the longevity of rod photoreceptors, indicating their contribution to age-related disease susceptibility.

Rod photoreceptors require vast amounts of energy to sustain vision and are thus vulnerable to metabolic stresses that accompany aging. Energy deprivation of photoreceptors is believed to be a key driver of neurodegeneration of the retina.

Neurons, specifically photoreceptors, prefer glucose as a source of energy, but in aging, we surprisingly observed utilization of fatty acids as well. These studies suggest how changes in aging rod functions can make them vulnerable to genetic susceptibility variations and environmental factors, which together cause common blinding aging-associated diseases, Swaroop said.

Our work provides pivotal connections between aging, the epigenome, dysfunction of the cells mitochondria, and diseases such as AMD. The findings have broad implications for how we understand age-associated neurodegeneration, not only in the eye, but elsewhere in the body, he said.

Future studies will assess whether DNA methylation contributes to alterations in the expression of metabolic genes and thus introduce epigenomic editing as a therapeutic possibility for age-related retinal disease, said the studys first author, Ximena Corso-Daz, Ph.D., a postdoctoral fellow in the Neurobiology, Neurodegeneration, and Repair Laboratory.

The study was supported by NEI Intramural Research Program grants ZIAEY000450 and ZIAEY000456.

This press release describes a basic research finding. Basic research increases our understanding of human behavior and biology, which is foundational to advancing new and better ways to prevent, diagnose, and treat disease. Science is an unpredictable and incremental process each research advance builds on past discoveries, often in unexpected ways. Most clinical advances would not be possible without the knowledge of fundamental basic research.

NEI leads the federal governments research on the visual system and eye diseases. NEI supports basic and clinical science programs to develop sight-saving treatments and address special needs of people with vision loss. For more information, visit https://www.nei.nih.gov.

About the National Institutes of Health (NIH):NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov.

NIHTurning Discovery Into Health

Corso-Daz X, Gentry J, Rebernick R, Jaeger C, Brooks MJ, Asten FV, Kooragayala K, Gieser L, Nelissery J, Covian R, Cogliati T, Mondal AK, Jiang K, Swaroop A. Genomewide profiling identifies DNA methylation signatures of aging in rod photoreceptors associated with alterations in energy metabolism. Published April 21, 2020 in Cell Reports. DOI 10.1016/j.celrep.2020.107525

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Neo-wars: masks and muskets – Daily Times

Coronavirus, a microscopic germ, has literally brought our so-called advanced human civilisation to a grinding halt. The pandemic has pushed humankind in the age of neo-wars, characterised by non-military threats, notably pandemics and climate change.

Amid the surging death toll and the consequent disruption in human life, from economy to religion, all stand corona-ised. From individuals to nations, all stand quarantined. Both laymen and leaders are struggling to figure out what and why it has struck them so suddenly, swiftly, comprehensively, and conspicuously. Some are trying to find answers in their belief in the wrath of God, whereas others are finding solace in common sense defying conspiracy theories.

The global bewilderment is rooted in our general ignorance about the history of the evolutionary battle between microbes and humans. The current pandemic is neither the first nor the last as the clash between germs and humans is a part of the relentless evolutionary process that obliges microbes to infect, reproduce and spread to survive. In response, humans evolve their countermeasures to kill the deadly germs with antibiotics or antivirals.

According to the World Economic Forum, the Antonine Plague (165-180 AD, death toll 5 million), Black Death (1347-135, death toll 200 million), Third Plague (1885, death toll 12 million), Spanish Flu (1918-1919, death toll 40-50 million), Hong Kong Flu (1968-1970, death toll 1 million), HIV/AIDS (1981-present, death toll 25-35 million), SARS (2002-2003, death toll 770), Swine Flu (2009-2010, death toll 200,000), Ebola (2014-2016, death toll 11,000), MERS (2015, death toll 850), and COVID-19 (2019-Present, death toll 58,700) are some of the pandemics that human beings battled or continue to confront.

Like any contagion, the coronavirus will recede after peaking, leaving us with ample time to pause, reflect and change to be better prepared for next time

Comparatively, the death toll caused by the coronavirus is insignificant so far. However, COVID-19 is taking an unprecedented psychological, political and economic toll, owing to a highly globalised world underpinned by greater economic interdependence and digital connectivity that are turning to be its Achilles heels. A global lockdown means disruption in the global economic chain and consequent economic slowdown, threatening people with the scary spectre of job losses and decline in living standards. Thanks to social media, the pandemic of panic and uncertainty has proliferated faster and wider than the virus.

Due to the fear of infection, we are afraid to touch the very gadgets that define and drive our modern life. The contagion has injured the collective human ego and vanity, leaving us impeccably stunned. We are unable to reconcile ourselves with the novel and nightmarish scenario unfolding in slow motion, like a Hollywood thriller.

The splitting of atom, missions to moon, elimination of certain diseases, increased human longevity, and greater food production were mistaken for human conquest of nature. Arbitrarily, humankind proclaimed itself as the crown of the creature resulting in misleading triumphalism, fuelled by material advancement. Challenging our crown, the coronavirus has shocked us out of smugness and shattered our illusions about homo sapiens triumph and supremacy on the planet.

The reason why the global community is finding it hard to fight off the viral challenge is not because it is deadlier than the past pandemics, but because we have been caught unprepared, clueless, and ill-equipped despite having better technology than before. The coronavirus has exposed the hollowness of our moral conventions, religious institutions, politico-economic structures, so-called national security, popular leadership, technological prowess, and medical science, all of whose direction and thrust have turned out to be misconceived and misfocused.

Militarily, the world may be better equipped and prepared to repel an alien attack than fighting off the coronavirus invasion. The data from the Stockholm International Peace Research Institute reveals that the total world military annual expenditure is around US$1,822 billion, whereas the global health annual spending is about US$ 7,800 billion. Seemingly, the world health budget outweighs the global defence allocations. The total world population is over 7 billion souls whose good health is to be ensured by US$ 7,800 billion, whereas US$1,822 billions are spent on overall requirements of merely 27,414,000 armed forces personnel maintained for state security. Tellingly, the statistical juxtaposition lays bare the serious inadequacy of global health budgets considering the size of the world population and vitality of human health.

Ironically, poor nations like India and Pakistan, with shabby health infrastructure, never tire of bragging about their sophisticated nuclear doctrines and nuke stockpiles, gathering dust at the cost of human security of the millions of people perennially afflicted by hunger, poverty, and ignorance. Generally, nations are oversupplied with nuclear doctrines and national security strategies, but lockdown plans are insufficient. What nations have are modern muskets not masks; nuclear weapons not ventilators; bunkers not hospitals; armoured vehicles not ambulances; soldiers not doctors, nurses and policemen, who have emerged as the neo soldiers in this neo-war.

Humanitys war on the coronavirus is more complex than war on terror. The vulnerability of an underpaid, under-protected and overworked doctor, nurse or policeman to the virus during long duty hours and direct exposure is far greater than that of a soldier to an enemy bullet or bomb.

Like any contagion, the coronavirus will recede after peaking, leaving us with ample time to pause, reflect and change to be better prepared for next time. Humanity needs a radical shift in its infected intellectual approach to mother nature on which we are helplessly dependent rather than being its masters. We are just one of the millions of species on this tiny blue dot of dust we call Earth, suspended in infinity of universe. The party is over, and it will never be business as usual. In the contemporary age of human caused sixth mass extinction and climatic turbulences, the future of humanity hinges on the choices we make in the post-coronavirus world. A peace accord with nature, forensic reviews of politico-economic and religious institutions, reorientation of science and technology, sustainable development, prioritisation of human security, healthy health infrastructure, and population control are some of the wise measures expected of us, the homo sapiens, the so-called wise beings. The real enemy is not the coronavirus; humanity has to be saved from humans as our insatiable desire for more and more is unnatural, unsustainable, and suicidal.

The writer is a PhD scholar and can be reached at mahar.munawar2017@outlook.com and on Twitter @MunawarMahar

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Neo-wars: masks and muskets - Daily Times

LeBron James is No Human. He is a Freak of Nature: Former NBA Player Explains Why This is Not His Last Opportunity – Essentially Sports

LeBron James is one man who has established himself as one of the modern greats of the game. His career has been on an upward trajectory ever since he was drafted by the Cleveland Cavaliers in 2003.

There is no doubt that James works hard. He is currently in his 17th regular season in the NBA. But with this longevity comes the question of how long he can continue in the league.

Rachel Nichols is the host of the program Jump which airs on ESPN. Former stars Kendrick Perkins and Richard Jefferson joined her in a recent episode, speaking about everything NBA.

Nichols asked them if LeBron James can really carry on his current playing style into the next season. She further asked if this is his last real window to win a title with the Los Angeles Lakers.

Jefferson had his take on the question and replied: There might be a drop off when he turns 36. But hes got Anthony Davis, hes got a great team around him. So will this be his last chance to win a championship? No.

Perkins similarly had a response that would fire up LeBrons fans. LeBron James is no human. He is a freak of nature. And when it comes to professional athletes taking care of their bodies, LeBron James is one of one, stated the 35-year-old.

Perkins boldly stated that James can go playing at the top for the next five years. Hes a guy who invests a lot in his body, one of the best Ive ever seen, he added. He claimed that with the work rate James was putting this season, he is on his way to reclaim the throne as the leagues MVP, if the season should resume.

Jefferson then pointed out that James has changed his game this year. Hes been leading the league in assists with 10.5 assists per game. Jefferson states if he develops his game in this aspect he will prolong his career.

With players like LeBron James, you never know. He has been proving his skill on the court for 17-years straight. With his hunger and determination, no one can predict what he can achieve with the Lakers next season or the season after that.

James has been averaging 25.7 points, 7.9 rebounds and 10.6 assists per game this season. He can still do wonders with the ball. It is entirely up to LeBron James on how long he wants to keep playing. In his mind, if he wants to retire in his prime after winning a championship and an MVP award, he will.

Or, he can decide to play more. James has the advantage of choosing his path. At the end of the day, it is he who will make the ultimate decision.

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LeBron James is No Human. He is a Freak of Nature: Former NBA Player Explains Why This is Not His Last Opportunity - Essentially Sports

‘Human rights don’t have a best-before date’: COVID-19 lays bare rampant ageism – The Globe and Mail

A makeshift memorial is seen at the CHSLD Yvon-Brunet, a long-term care home in Montreal, on April 13, 2020.

Paul Chiasson/The Canadian Press

Four more deaths, all elderly.

For the family of John Fox, already in mourning, those words cut like a knife in a fresh wound.

The retired RCMP officer had died earlier that day of COVID-19 at the age of 73.

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Suddenly, he was just a statistic, part of a throwaway line on the evening news. Hearing Mr. Fox described as elderly, albeit anonymously, shocked the family.

That word is so laden, so dismissive, says Margaret Gillis, his sister-in-law.

And so common.

Coronavirus guide: Updates and essential resources about the COVID-19 pandemic

How many coronavirus cases are there in Canada, by province, and worldwide? The latest maps and charts

What are the coronavirus rules in my province? A quick guide to whats allowed and open, or closed and banned

What is the implication when you describe someone as elderly? That they are unimportant? Disposable? Ready to die?

Ms. Gillis says those are assumptions we make all too often about people of a certain age.

And she would know.

In addition to losing a loved one to the pandemic, Ms. Gillis is president of the International Longevity Centre (ILC Canada), a group that advocates for the human rights of older people and against the rampant ageism in society.

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Johns death has made the pandemic more real for me, Ms. Gillis says. Its also given a new urgency to my work tackling the almost inbred ageism in society.

Ms. Gillis says that, on the surface, calling someone elderly may not seem like a big deal, but language matters because assumptions and prejudices permeate public policies.

We need not look any further than the horror story unfolding in nursing homes and long-term care facilities in Canada and around the world.

We have known from the get-go that people in institutional care were among the most vulnerable to a pandemic. Yet little was done to protect them.

News of outbreaks in facilities that house seniors trickles out when the situation become so dire that dozens die such as at the Rsidence Herron in Dorval, Que., or the Pinecrest Nursing Home in Bobcaygeon, Ont.

But its hard to even figure out how many outbreaks there are in these high-risk institutions, a reminder of the old adage: If you dont count it, it doesnt count.

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For the most part, older people dont count.

Weve seen that illustrated in the debates about what would happen if COVID-19 overwhelmed hospitals. Beds and ventilators would go first to younger people, not people with disabilities and the elderly.

In Italy, you could barely get in the door of a hospital if you were over 60, Ms. Gillis says.

The tales of older people found dead in nursing homes and in their homes in Spain and Italy are legion. Most didnt even get counted in the official coronavirus statistics.

Just more dead old people.

We have this attitude that people who are not seen as contributing to the economy have no value, Ms. Gillis says.

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In popular culture, you can joke about a persons age in a way you cant about their race or religion. We see this reflected too in popular memes like Okay, Boomer which has morphed into the more nihilistic Boomer Remover descriptor of coronavirus.

Many have played down the severity of the pandemic by saying it only kills old people. Others have suggested that, rather than the sweeping physical-distancing rules that have been imposed, we simply quarantine older people and let everyone else get on with their lives, or that we let coronavirus run wild so herd immunity develops and the old and the weak are culled.

Ms. Gillis says these crass approaches ignore the fact that human rights dont have a best-before date and that many, if not most, older adults have rich lives.

She points to her brother-in-law, saying that like all the others who have died in the pandemic, he is more than a statistic ... he was a spouse, a father, a grandfather who contributed a lot to his community.

Mr. Fox was a big bear of a man, healthy as a horse, with no underlying health conditions before he contracted coronavirus.

Shortly before he fell ill, he played golf; in recent weeks, he had been kayaking and hiking. Mr. Fox was an active volunteer with a therapeutic horseback-riding group for children with developmental and physical disabilities. Having seen far too many gruesome highway crashes over his police career, Mr. Fox was also a dedicated blood donor.

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Elderly was certainly not a label that fit.

But is it ever?

The Quebec government will inspect all 2,600 of the province's seniors residences to ensure proper care is being provided during the COVID-19 pandemic. The Canadian Press

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Here Are 9 Ways To Stay Informed and Protect Your Mental Health – Longevity LIVE

As the facts surrounding the global coronavirus pandemic continue to change at a moments notice, its important to stay informed on the latest news. Doing so can help us make informed decisions to better protect our health. However, as important as it is to stay up to date with the latest news, could we also be harming our mental health?

Its understandable that we all want to spend our free time reading everything about the coronavirus as it helps to provide us with a sense of control, which is what we need during these uncertain times. However, its clear that absorbing too much bad news can be harmful to both our mental and physical health.

According to a survey from the American Psychological Association, most adults admitted to following the news regularly, but 56 % shared that doing so causes them stress. Now with that said, why do we still find ourselves glued to our screens, enamored with every sensational headline?

The fact is being informed allows us to develop tools that we can use to better protect ourselves. Unfortunately, being informed can often come as a cost to our mental health. For instance, research published in the British Journal of Psychology found that after just 14 minutes of watching bad news, participants began to experience negative effects on their mental health. Whats more, heightened stress levels can weaken your immune system, which is the last thing you need especially now.

However, this doesnt mean that you should give up on staying informed and engaged. In fact, there are ways for you to stay informed without compromising your mental health.

Similar to how you establish screen time limits for your kids, you should also set your own time limits when it comes to reading the news. Clicking on a link with a sensational headline can catapult you down a rabbit hole of never-ending information. However, by setting an alarm, you can pull yourself out before you get in too deep and compromise your mental health.

Try to figure out how much time youll need to read the news, and set an actual timer on your phone, be it for 5, 15, or 30 minutes or even an hour. You should then decide how many times a day youll do it for say reading the news for 15 minutes three times per day. Once the time is up, close all your apps or tabs related to the news, and dont open it up again until the next time, or day.

In addition to timing yourself when it comes to reading the news, you should also remember to allocate time to other activities that are good for your mental health. This includes exercising, reading, or any other healthy hobbies.

Different news sources help to provide you with more perspective when it comes to current affairs. However, the constant and multiple news alerts and notifications on your phone can get overwhelming, raising your stress levels.

As such, it would be advisable to limit your notifications and only allow news alerts from sites that you deem necessary. In fact, more information is not necessarily the best way to stay informed. Instead of allowing a barrage of notifications to fill up your phone, rather choose just two or three of the most credible sources and ignore the rest. Sites such as the CDC and the WHO organization are the best sources as they provide the latest, and the most credible information surrounding the coronavirus.

When a news story breaks, were all glued to CNN or refreshing our Twitter timelines in an effort to get the latest updates. While normal, this action can affect your mental health. This is because when a news story breaks, it takes a while to get all the facts straight and oftener than not, the information we see online is more so based on half-truths, speculations, and even conspiracy theories. As a result, these stories may serve to get our attention, but they also serve to increase anxiety and stress levels.

As it takes some time for journalists to collect all the facts, it would be advisable to wait for them to provide a more accurate and well-rounded report.

The last thing you want is to be going to bed with news anxiety, as this will disrupt your sleep, and this is the last thing you need. In addition to weakening your immune system, lack of quality sleep can also affect your mental health by increasing the risk of depression.

Its important to never check the news before bed. This is because you want enough time during the day to process the information. During the day, if you read something that raises your stress levels, youll be able to engage in stress-relieving techniques such as yoga or meditation. Its also advisable to not sleep with your phone too close to you as you may be tempted to read the news as soon as you wake up.

With the constant influx of infection rates and death tolls, the news can get quite depressing. However, its important to remember that there are good things happening in the world. The bad news does not provide a full picture of the days events.

Reading good news can help to relieve some stress accumulated by bad news. So, try to read up on some human interest stories or you can also follow sites like the Good News Network, Positive News, and Optimist Daily.

In addition to getting some good news, you should also try focusing on issues that you can help solve. As the coronavirus pandemic has affected various people in different ways, why dont you go out of your way to research how you can help them? For ways to get involved, or help make a change, check out Global Givings Coronavirus Relief Fund.

Starting your day reading bad news can affect your mood. So, its important to start your day on a more positive note.

Try starting your day by listening to a relaxing podcast that boosts your mood, exercising, meditating, or by even enjoying a cup of coffee on your porch, enjoying the tranquil silence.

If youve been consuming the news, and youre feeling overwhelmed, its important not to suppress your feelings. Doing so can make things worse.

Instead, try reaching out to a friend or family member and talk about your feelings. Additionally, your area may be on lockdown, but psychologists and counselors are still operating online. Therefore, dont shy away from contacting your nearest mental health counseling group.

Yes, you should reach out if you are feeling overwhelmed with crippling coronavirus anxiety. However, you can also make the conscious decision not to discuss the coronavirus if you believe that doing so affects your mental health.

When it comes to the coronavirus, everyone has an opinion, and theyre each looking to share it. As a result, we often feel forced into a conversation. However, youre allowed to not engage if you feel that doing so can bring your mood down. Feel free to change the subject to something more positive.

If all else fails, feel free to simply step back and unplug.

Youre allowed to protect your mental health. If you feel that you need to disconnect from time to time, feel free to do so. Uninstall all your social media apps and disconnect from all news outlets for a period of time. Ask a close friend or family member to only alert you if something is going on that you need to know about.

Yes, its important to stay up to date with the news as this can help us to make more informed decisions. Unfortunately, too much news can affect our health, and thats the last thing we need right now.

Thankfully, there are ways to protect our health and stay informed.

Johnston, W.M. and Davey, G.C.L. (1997), The psychological impact of negative TV news bulletins: The catastrophizing of personal worries. British Journal of Psychology, 88: 85-91. DOI:10.1111/j.2044-8295.1997.tb02622.x

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Helen Dotan-Glassberg selected as Top VP of Human Resources & Talent by the International Association of Top Professionals (IAOTP) – Life Pulse…

Israel, Haifa District 04-13-2020 (PRDistribution.com) Helen Dotan-Glassberg, VP of Human Resources & Talent Development for Shamir Optical Industry Ltd., was recently selected as Top VP of Human Resources & Talent for 2020 by the International Association of Top Professionals (IAOTP) for her outstanding leadership and commitment to the industry.

Inclusion with the International Association of Top Professionals is an honor in itself, only a few members in each discipline are chosen for this distinction. These special honorees are distinguished based on their professional accomplishments, academic achievements, leadership abilities, longevity in the field, other affiliations and contributions to their communities. All honorees are invited to attend the IAOTPs annual award gala at the end of this year for a night to honor their achievements.With over 20 years of professional experience serving as a Vice President of Human Resources and Manager of Human Resources, Helen has certainly proven herself as an accomplished professional and expert in her field. As a dynamic, results-driven leader she has demonstrated success in Career Development, Performance Management, Team Building, Organizational Development, Recruiting, Deferred Compensation, Talent Acquisition, Management Development, Employee Relations, HR Consulting and HR Policies.Her impressive repertoire of prior roles include experience within the renewables and environmental industries. She served as VP of HR for Amiad Water Systems Ltd., VP of Human Resources for Medingo, a Roche Company, Director of HR for Surf Communications Solutions and HR Manager of EVS/Granit Mesima.Currently, Helen is employed with Shamir Optical Industry, Ltd., an Israel-based company, which is engaged in the development, design, and manufacturing of premium progressive lenses and molds for the ophthalmic industry. This is a fully owned subsidiary of Shamir Insight, Inc (San Diego, CA). Serving as the Sales and Marketing center for the USA, Canada, Central/South America and Mexico, Shamir Insight specializes in the marketing of premium progressive lenses under the product brand names such as Shamir Autograph III, Shamir Autograph !!, Shamir InTouch, Shamir Spectrum, Shamir FirstPal, Shamir Golf, Shamir Relax, Shamir Attitude III, Shamir Duo, Shamir Computer and Shamir WorkSpace.Before embarking her current career path, Helen earned a Master of Arts in Sociology- Organizational Behavior from Haifa University in 2002. Stephanie Cirami, President of IAOTP states, Choosing Helen for this honor was an easy decision for our panel to make. She is a good communicator, displays high integrity in all business endeavors and is a true leader within her role. We are looking forward to honoring her on stage, this year at the Plaza Hotel in New York City at IAOTPs 2020 Annual Awards GalaThroughout her illustrious career, Helen has been recognized worldwide for her leadership and commitment to the field. This year she will be considered for a feature in T.I.P. (Top Industry Professional) Magazine and was chosen as Top VP of Human Resources & Talent by the International Association of Top Professionals (IAOTP). For 2021 she will be considered for the Empowered Woman of the Year Award, based on her extensive knowledge and tremendous foresight as a Human Resources Professional.Looking back, Helen attributes her success to her persistence, positive leadership and mentors she has had the pleasure of working alongside. Her depth of HR expertise and having diverse international business experience are what has driven her to succeed on so many levels. For the future, she aspires to continue growing as a professional and making a difference to help others achieve their goals in the business world.About IAOTPThe International Association of Top Professionals (IAOTP)is an international boutiquenetworking organization who handpicks the worlds finest, most prestigious top professionals from different industries. These top professionals are given an opportunity to collaborate, share their ideas, be keynote speakers and to help influence others in their fields. This organization is not a membership that anyone can join. You have to be asked by the President or be nominated by a distinguished honorary member after a brief interview.IAOTPs experts have given thousands of top prestigious professionals around the world, the recognition and credibility that they deserve and have helped in building their branding empires. IAOTP prides itself to be a one of a kind boutique networking organization that hand picks only the best of the best and creates a networking platform that connects and brings these top professionals to one place.For More Information on IAOTP please visit: http://www.iaotp.comWatch Gala Video

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Market Insight: What Does the Sustainability & Climate Change Profession Look Like During, and After, COVID-19? – CSRwire.com

Apr. 07 /CSRwire/ - Communication and transparency are important right now. It is useful to share perspectives and information. Brevity is also important as there is a lot for us all to do, so here is a short update of Acre's observations.

How is the current situation impacting the employment market?

Some organisations and industries have been hit hard by coronavirus, and our thoughts are with them, but there are plenty of organisations that have the opportunity to keep on trading unimpeded, or that may see a benefit from the current scenario.We have observed the following:

Existing recruitment processes have generally continued:About 80% of companies have continued their hiring processes despite the challenging backdrop. The number of interviews we are organizing has not dipped probably aided by the ease of video technology.

Companies are making hiring decisions based on video conference interviews:The majority of companies are willing to make hiring decisions based on videoconference interviews, so as not to lose momentum in recruitment processes

Purpose-driven jobs are still being created:Albeit at a reduced level, we have continued to take on a number of exceptional new assignments across all our global territories. We will continue to post these on our website and onLinkedIn, where appropriate.

What is the long-term outlook for the professions?

Our work focuses on system-level issues that need to be addressed over years, not months - in the wake of coronavirus these challenges will remain. Whats more, the current status quo is likely to galvanize a move towards a more sustainable global economic model.

The market has been growing:Over the past two years, Acre has experienced an acceleration in the growth of the sustainability employment market, driven by heightened corporate engagement, grass-roots mobilization, increased consumer awareness, regulatory pressure, and commitments that span borders, such as the Paris Climate Agreement.

There has also been a shift in the focus of the investment community for even greater standards of board accountability on how their business is adapting to a two-degree climate scenario.

Commitment to climate change is high:Whilst the 2008 recession reduced commitment to climate issues (some companies were recruiting Climate Change Directors prior to this point), climate change mitigation and adaptation is much more embedded in the makeup of our socioeconomic systems now, and as many have observed, the coronavirus epidemic may serve to enhance this further.

Opportunities will emerge:The 2008 recession had other positive impacts for the sustainability profession. For instance, companies began to look at how to achieve financial efficiencies within their businesses. For this reason, we experienced an enhanced demand for energy managers as companies looked to reduce their energy costs. The sustainability profession is diverse; amongst issues such as wellbeing, business ethics, supply chain, and circular economy there will be areas that are not only well sheltered but become more critical over the coming months.

Sustainability as a profession may be enhanced:Beyond 2008, companies who were focussed on achieving longevity began to evolve their perception of sustainability away from a CSR and public relations exercise, to a core strategic opportunity and a driver of business innovation. In an environment of challenge and constraint, it was inevitable that sustainability would have to account for itself.

The importance of sustainability is likely to be enhanced again, particularly as this time the issue is caused by a specific challenge that our profession will have a role in tackling.

Healthy, safe and well citizens:Inside and outside of business, there will be enhanced scrutiny of how people were treated during this time. Since the rise of social media and the public outcry at footage from events such as the Rana Plaza Factory collapse in Bangladesh in 2003, the world will be looking at how workforces and supply chains have been protected from both a health and an economic perspective. An increased value will be placed on functions that support this endeavour.

What is our collective role?

Companies and those who lead them have an obligation to play a positive and constructive role in supporting society to navigate the temporary challenge that we face.Our role is as follows:

To stay focused on the challenges we address:Coronavirus has swept across society quickly, so its effect is obvious however the impacts of climate change, ocean plastics, loss of biodiversity, poor air quality and human rights are enduring issues which pose enormous challenges and threats. It is essential not to lose sight of this.

To mobilize our teams to support:The sustainability profession has been responsible for the greatest feats of industrial collaboration in history (think multi stakeholder-initiatives) and we must collectively leverage this experience now - we all have a responsibility to support each other at times like this. Please pick up the phone if we can support you or provide information which will help with your personal decision making. We are enriched, energized and humbled by the open dialogues we are having with our clients and stakeholders.

To instill confidence in the market:To the best of our ability, we will continue to take a business-as-usual approach. At Acre, we are supporting our employees, sharing our progress with the market, and exploring how we can adapt in certain areas where market constraints currently exist.

Our pace remains the same our professions remit is vital to societal and environmental adaptation and we will press ahead with full commitment.

Please feel free to reach out to discuss any of the observations made above.

From all of us, we hope that you and your families are in good health.

Andy Cartland, Founder of Acre

About Acre

Sustainability & EHS Recruitment and Talent Development

Acre connects forward thinking organisations with purpose driven professionals. We work with functions which focus on resolving systemic challenges that impact society and the environment at a global level. These functions include; Sustainability and CSR, Corporate Affairs, ESG and Sustainable Finance, EHS as well as Energy and Clean Technology. To learn more, visitacre.com

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Market Insight: What Does the Sustainability & Climate Change Profession Look Like During, and After, COVID-19? - CSRwire.com

The herd and the mob – Prince George Citizen

Early in the pandemic, there was some talk by wishful politicians that herd immunity would be enough to deal with the coronavirus, that shutting down vast sections of the economy and putting millions out of work wouldnt be necessary. The idea was that enough people would be exposed, be mildly sick for a short time and then be immune, able to work and protect others.

Two problems with COVID-19 made herd immunity impossible. First, the ability for asymptomatic people to spread the virus for days, a fact well-known early in the pandemic, despite the senior politicians proclaiming as late as last week that they had no idea. Second, COVID-19 makes people far sicker for far longer and kills far more people than the average flu, again despite political leaders and American broadcasters insisting for too long, well into late March, that it was just another flu.

Herd immunity is what makes childhood vaccinations work so well. If the vast majority of children are vaccinated for measles, mumps, rubella, chickenpox, pertussis and so on, they form a wall of protection around the small group of children unable to be vaccinated due to underlying health conditions.

If there is one silver lining in this pandemic cloud, its hopefully that weve heard the last of anti-vaxxers. It will be a vaccine, after all, that will protect humans from COVID-19. Sadly, that vaccine wont come in time to save millions of people around the world, in our country and in our province.

Modern society has allowed many people to unplug from the herd. In a much earlier time in human history, selfishness, individuality, being a loner, going your own way was suicidal. The only way for early humans to survive in a hostile environment with few resources was to band together. Self-survival was intimately tied to the health and well-being of ones neighbour and the overall herd.

Human evolution experts are increasingly convinced by the fossil record and other evidence that homo sapiens survived while other forms of early human, such as Neanderthals, didnt because homo sapiens were better team players, using their imagination to adjust to new situations with innovative approaches to further the longevity of the herd.

In other words, survival of the fittest isnt individual brute strength, self-interest and mercilessly culling out the weak. Its kinship, collaboration and kindness.

The herd ethic isnt perfect, of course. The mob mentality is also a manifestation of the herd. Otherwise sensible people have found themselves looting, hoarding, rioting, wilfully putting themselves and others in danger and later cant explain why, their behaviour as senseless and against their self-interest as the creatures mindlessly following their neighbour off a cliff.

Fortunately, the mob never prevails, although it can do catastrophic damage in a short time, up to and including destruction of itself and the herd (sounds like a virus, doesnt it?).

Fortunately, that is rare. If it were more common, homo sapiens and the many other herd creatures wouldnt be here today.

The herd endures.

Its more than selflessness and altruism leading so many people to do the right thing - healthcare workers putting themselves at risk to treat people they dont know, essential workers showing up for their shifts, families staying home to protect themselves and others from COVID-19.

Thats the herd programming, hardwired deep in our brains, at work.

Thats the elephants and the bison and the musk ox forming a circle around the most vulnerable members of the herd while facing the external threat head-on.

For them and us, then and now, the herd is salvation, the mob annihilation.

Read the original:
The herd and the mob - Prince George Citizen

10 Habits to Transform Your Mindset During Lockdown – Thrive Global

With an unprecedented proportion of the worlds population in self-isolation, many of us feel uneasy (to say the least) about the sudden, strange upheaval to regular life as we know it. There is no doubt that, on top of the serious physical respiratory health pandemic, a tsunami of associated mental health issues is rapidly sweeping the globe.

It is totally normal and understandable to flip between a multitude of mental and emotional statesduringtheCOVID-19outbreak. Researchers recorded feardepression, anxiety and post traumatic stress disorder in China during the outbreak. Other studies found depression and anxiety levels to rise in the UK, following the announcement of the governments lockdown policy.

As health-optimizing, best-selling author Aubrey Marcus recently shared:

Its okay to feel what you are feeling, whatever that is. Dont feel ashamed if you arent positivePeople misunderstand what being strong really is. Strength is the courage to be vulnerable, be real. Some days I feel empoweredsome days I feel helplessThis week Ive had heaping doses of both polarities. Most people Ive spoken to have felt similar. Its all okay. Aubrey Marcus

Although we might not go actively looking for them , lifes toughest challenges also provide the opportunity to shake up our lives and realise what matters most. After struggling with several big life changes myself a few years ago, I focused on what seemed to help keep me emotionally stable and happy even in the midst of external turmoil.

The pandemic is like a collective challenging life-change the world is battling serious illness; anxiety; financial woes; separation from loved ones; grief; a temporary loss of freedom instability in multiple areas en masse.

Healthy relationshipsare key for our well-being. The 80-year Harvard Study of Adult Development found that close personal connections are key for our happiness and longevity throughout life. Research also suggests that people who engage in supportive, positive relationships produce more oxytocin, which can: boost our immune system, allow us to physically heal quicker, and mean we are less likely to experience stress, anxiety, and depression.

Technology is often blamed for making us feel more socially isolated (more on that later on); but most of us are using it now to build a sense of real-life community that we might miss at the moment. Commit to speaking to at least one person who uplifts you on a phone or video call every day. You can arrange to share meals, play online games, or have creative sessions with loved ones using apps like Zoom or Houseparty. You can even host virtual dinner parties by eating meals at the same time as those we miss; or have virtual book or movie clubs where you discuss a book you are all reading, or film youve watched, on scheduled calls.

Social media self-isolation support groups (global on Facebook, local on Nextdoor, or you can make your own using Whatsapp) are popping up to help members stay positive. These groups can help us pool resources and knowledge; share how we feel; and find the support we need.

As well as contacting those we trust and feel positive with when we are struggling, reaching out to others who might be feeling alone, anxious or overwhelmed can also help us get through hard times together. Every morning when you wake up, try to think of two people you could check in with that day with a message, call or supportive voice note . Helping others is also known to help boost our own mental well-being.

Supporting small businesses online can help those struggling with low in-person footfall. We can also donate to local food banks, homeless shelters, services for the elderly or COVID-19 appeals like the UKs National Emergencies Trust, or volunteer to help the NHS support those most in need.

If you live with other people, keep in mind that we all deal with stress differently, and all have up and down days. In general, try to take a few breaths before reacting to someone elses emotionally-triggering behavior, and to be open about how you feel and your needs perhaps using the Nonviolent Communication method to build understanding rather than resentment.

This recent Freakonomics podcast episode discusses the effects of the pandemic on urban populations and marriages. Tim Ferriss COVID-19-related podcasts have been super-insightful, and his recent interview with acclaimed relationship therapist Esther Perel is packed with useful lockdown coping strategies. There is more practical advice for isolating with your family in this LBC Radio interview.

Healthy relationshipsare key for our well-being. The 80-year Harvard Study of Adult Development found that close personal connections are key for our happiness and longevity throughout life. Research also suggests that people who engage in supportive, positive relationships produce more oxytocin, which can: boost our immune system, allow us to physically heal quicker, and mean we are less likely to experience stress, anxiety, and depression.

Technology is often blamed for making us feel more socially isolated (more on that later on); but most of us are using it now to build a sense of real-life community that we might miss at the moment. Commit to speaking to at least one person who uplifts you on a phone or video call every day. You can arrange to share meals, play online games, or have creative sessions with loved ones using apps like Zoom or Houseparty. You can even host virtual dinner parties by eating meals at the same time as those we miss; or have virtual book or movie clubs where you discuss a book you are all reading, or film youve watched, on scheduled calls.

Social media self-isolation support groups (global on Facebook, local on Nextdoor, or you can make your own using Whatsapp) are popping up to help members stay positive. These groups can help us pool resources and knowledge; share how we feel; and find the support we need.

As well as contacting those we trust and feel positive with when we are struggling, reaching out to others who might be feeling alone, anxious or overwhelmed can also help us get through hard times together. Every morning when you wake up, try to think of two people you could check in with that day with a message, call or supportive voice note . Helping others is also known to help boost our own mental well-being.

Supporting small businesses online can help those struggling with low in-person footfall. We can also donate to local food banks, homeless shelters, services for the elderly or COVID-19 appeals like the UKs National Emergencies Trust, or volunteer to help the NHS support those most in need.

If you live with other people, keep in mind that we all deal with stress differently, and all have up and down days. In general, try to take a few breaths before reacting to someone elses emotionally-triggering behavior, and to be open about how you feel and your needs perhaps using the Nonviolent Communication method to build understanding rather than resentment.

This recent Freakonomics podcast episode discusses the effects of the pandemic on urban populations and marriages. Tim Ferriss COVID-19-related podcasts have been super-insightful, and his recent interview with acclaimed relationship therapist Esther Perel is packed with useful lockdown coping strategies. There is more practical advice for isolating with your family in this LBC Radio interview.

Just a few minutes of meditation day has been shown to have a multitude of positive effects on our mental and physical well-being, and now might be a great time to start. Over the medium-term, research has shown that meditation can help calm down anxious racing minds; decrease stress and depressive feelings; give us new perspectives; and find inner stillness even when the outer world seems tumultuous.

Set up a comfortable, quiet space with a cushion, blanket, candle or other elements which make your spot enjoyable to go to. Head there at a regular time for example at 8am; before you go to bed; or after you brush your teeth to make it more likely that you keep going back.

There is an ever-growing treasure trove of free and paid-for meditation material online. Insight Timer is my favorite meditation app for variety and the community aspect; the Calm app has a free Lets meet this moment together section to soothe COVID-19-related anxiety; and Australian Smiling Mind also has this dedicated Thrive Inside resources page.

Many of the worlds best-known meditation guides (such as Jay Shetty) are busy sharing positive-mindset content on social media; and studios like Unplug Meditaton in California are streaming classes online to help us calm down too. Alchemy of Breath also runs free online breath-work meditation classes every Sunday which can be particularly transformative to our mood.

Megan Monohans book Dont Hate Meditate is a great practical introduction to building a practice; and Deepak Chopras Hope in Uncertain Times site is offering a free 21-Day Meditation Experience.

To be mindful means staying non-judgmentally aware of the present moment rather than mind-wandering into thoughts about the past or the future (which is believed to make us less happy). During difficult times its easy for our attention to drift to worries about worst-case scenarios that may never happen. The fact is, no one really knows what the future holds. It is prudent to be practically prepared, but after that it is helpful to remember that we are safe in the present moment, rather than diving into negative thought spirals.

Meditation is a concentrated, dedicated period of mindfulness, but we can also practice staying mindful or to keep bringing our full attention to during other tasks.

A few easy ways to practice mindfulness include:

Some of my favorite books further exploring mindfulness, consciousness and living in the present moment include the beautifully written The Untethered Soul by Michael A. Singer; the esoteric The Power of Now by Eckhard Tolle; and mind-blowing Freedom From The Known by J. Krishnamurti. You can watch Tolles recent Staying conscious in the state of adversity video here.

Try to build some kind of routine at home you might decide to wake up, go to sleep and eat at regular times; take up exercise on certain days; or diarize blocks of your calendar for work and other tasks. This can help to help maintain our sleep patterns, to eat more healthily and stress less.

Its useful to list things youd like to achieve tomorrow (highlighting three top priorities), as well as the week ahead in your journal, carrying any unfinished tasks forward to the next time period. You can find tips on productively working from home online, like in these articles by the BBC and CNN.

If youve wanted to read a book (here are 10 books that totally transformed my life); learn a new skill (like a language); or take an online course (you can check many affordable or free ones out on Udemy or Coursera) but havent prioritized it take this extra time indoors as an opportunity. Hal Elrods easy read The Miracle Morning suggests activities to start our day off right, including exercise, meditation, reading, journaling and visualization. I personally like to meditate each morning, exercise in the afternoon, and read before I go to bed this structure helps me to stay grounded. I also like to mix up how I exercise, books I read and my self care routine, depending how I feel that day.

To work on forming good habits, or getting rid of old ones, James Clears Atomic Habits is a great guide to getting started. Using a journal, a highly-visible habit tracker, app or having an accountability buddy also helps us stay on track. To help my focus levels, I like listening to calming background music such as this on YouTube, or you can check out scientifically-backed Brain.fm.

Being at home all day means that many of us are spending more time than ever socializing, working, informing and entertaining ourselves through our online devices. The majority of Brits use their smartphones right up until bedtime and, in 2019, the average American checked theirs 96 times per day. Studies have linked heavy smartphone use to stress, depression and anxiety, with too much social media particularly found to affect our mood. Most of us have also likely noticed the associated effects of overuse on on our sleep, focus and productivity at home.

We can use usage-tracker apps like iPhones Screen Time, or Digital Wellbeing for Android to see how much time we spend on our devices usually its way more than we consciously realize! Then its down to simple hacks like having a phone-free room at home (like your bedroom) or times of day (like 9pm to 9am); turning off all but essential notifications; keeping your phone of arms reach when you are working; and deleting social media or other potentially time-wasting apps to declutter your home screen.

Check out the brilliant book How to Break Up With Your Phone by Catherine Price for more tips. Many of us are also enjoying digging out paper books, board games, gardening, baking or exercise equipment for offline entertainment.

Its important to stay up-to-date with key developments, but if you start to feel overwhelmed by negative news, follow the CDCs advice and take a break from it. Over half of participants in a 2018 study by the American Psychological Association said that the news causes them stress, with many experiencing anxiety or sleep loss as a result. Try not to have news on in the background check once a day for updates, rather than constantly, and set a time limit on how late youll consume it at night. Notice how you feel before and after you check the news. If you feel like you are compulsively checking, give someone you care about a call, or do something productive, like picking up a book, instead. Alternatively you can even check out Positive News for pandemic respite. The Centre for Evidence-Based Medicine also has a dedicated COVID-19 page that is updated daily to debunk related fake news.

At a Flying with Confidence course a few years ago, my fellow flight-phobic attendees and I were recommended to avoid watching fictional, Aircraft Investigation-style, TV shows about plane crashes the human brain has a tendency to normalize the catastrophes and outliers we see on TV. It can be tempting to consume all of the apocalyptic Netflix programming we can, in an attempt to understand all of the unknowns. In the same, I am avoiding watching this too, and focusing on uplifting or funny shows (my current favorite is Bojack Horseman) instead.

Laughter is known to make us feel better, and can soothe physical tension, strengthen our immune system and give us pain relief. Notice the small things that make you smile, and make sure you are regularly having fun doing things you enjoy like baking, drawing, dancing, singing, speaking to friends who cheer you up, watching or reading something that makes you smile. Think about what lit you up as a child, and dedicate at least 3060 minutes a day to activities that make you feel most happy and alive instead of consuming anxiety-inducing content.

Studies show that spending time in nature can have positive effects on our health like lowering our blood pressure and boosting happiness; and, for those of us in the Northern Hemisphere, Spring has sprung.

Try to spend time outside in your garden or patio every day, or go for a socially-distanced walk or run in the park or a natural space near you (as permitted by your local governments recommendations). Take the time to mindfully notice your surroundings any trees, flowers or birds you spot. Focusing on distant views can also give our eyes a break from all of the screen time at home.

You can connect with nature without leaving the house, too. Commit to noticing how the sky, or other natural phenomena like trees, look outside each day research suggests a window view of nature can even shorten the recovery time of patients. Owning a houseplant has also been shown to improve our mood; and listening to recorded nature sounds (I love hearing the ocean whilst I work) or looking at images of green environments are thought to also have calming effects on us. You could also install a bird feeder you can see from inside, and try to spend a significant proportion of your day in a room with adequate sunlight.

With all of the upheaval and uncertainty, many of us are finding it harder to nod off, with some reporting vivid dreams or nightmares once they do manage to. The American National Sleep Foundation recommends that adults get seven to nine hours of sleep per night; while the NHS explains here how being chronically under-rested can lead to serious health conditions including anxiety and depression.

For now, try developing a regular relaxing bedtime routine such as having three things you regularly do, like reading a book, having a herbal tea, a bath, journaling, meditating or moisturizing. Make sure your bedroom is as quiet and dark as possible, and avoid mental over-stimulation and blue light from our screens in bed which affect our sleep cycles by charging your phone outside of the bedroom. You could also try putting tech on airplane-mode at 9pm (and not checking your messages until 9am), or using free desktop tool F.lux which aims to keep the light levels coming from our screens with that of our natural environment according to the time of day.

Calms sleep stories have helped millions of people already, and HuffPost has some great tips here on sleeping better during pandemic-related anxiety. If you are interested in finding out more about our sleep qualitys effect on our health, Matthew Walkers book Why We Sleep is full of practical information and tips based on cutting-edge sleep-science.

The UK government recommends healthy adults do at least 2.5 hours of moderate exercise every week. Physical activity has many mental benefits such as improving cognitive function, boosting our perceived quality of life, and reducing anxiety and depression. If youre used to feeling the positive effects of going to the gym or playing sports, which you cant do right now, do not fear! Many of the worlds top fitness studios like Barrys Bootcamp, and instructors like Joe Wicks The BodyCoach TV, have moved to streaming regular free or paid-for classes online during lock down.

Research has found that lower intensity, strengthening movement like yoga (which also often includes a meditation section) can help calm us down during stressful times. Some of my favorite yoga teachers are also recording frequent classes from their social media accounts (like Ted McDonald on Instagram). I also love online ecstatic dance classes with URUBU or Rise Up basically, an excuse to dance like no one else is watching from the comfort of your living room, whilst connecting online to people from all over the world.

As well as dancing, singing has multiple health benefits too, and listening to music we enjoy is known to uplift our mood. There is a proliferation of DJ live streams and concerts going on check out this list of ideas if you are looking for something new.

We can all be guilty of being harsher to ourselves than we would be to anyone else learn to treat yourself like a best friend instead. If youre not feeling as productive as usual do what you can and know that youre trying your best during an unprecedented, stressful situation. This could also be an opportunity to rest a little from normal busy life, and to learn to forgive yourself if you are not feeling 100% (or failing to meet unrealistic standards).

As spiritual thought-leader Sadhguru recently half-joked to his 2.9m followers during his daily Instagram talk, the general public are saving lives just by staying home for once by doing nothing, we are doing something.

If you are comparing yourself with other peoples attitudes or achievements notice, and then try to put a stop to, doing that. We all handle things differently at different times, and we never really know what someone else is going through.

Acknowledging difficult feelings such as anxiety, grief, or boredom by sitting quietly with them and feeling where they come up in the body, and maybe sharing them with someone we trust, or a mental health professional can help us process and move through them, rather than repressing and paying for it later on. We can tell ourselves Ok, Im anxious/grieving/bored now, but that is normal and fine, and this too will pass after all these are not usual times!

Journalling or freewriting committing to writing whatever comes up for a set time duration (such as five minutes) or number of pages (three, for example) without editing or censoring ourselves can help us to get clearer on whats going on in our heads, and so make them feel less cluttered. Recording feelings can also be interesting to reflect on in future.

Keep in mind and check in with what feels useful to your own physical and mental state before and after you practice, then you will learn what works for you. You can find further COVID-19 mental health resources here:

If you are feeling unable to cope or overwhelmed, and speaking to someone close to you who you trust doesnt help you feel better, contact your family doctor or seek a professional counselor or therapist its often possible to have sessions remotely, over the phone or online.

These are uncertain times where many of us face grief, financial pressure, loss of freedom and anxiety so it is imperative to look after the physical and mental well-being of ourselves and others well during this period.

To summarize, try to regularly: meditate and practice mindfulness; build social connections; prioritize sleeping well; practice movement and a hobby you enjoy every day; regulate your tech use and consumption of negative content; and help others who are vulnerable, lonely or in particular need.

We can decide to not only survive and get through this period, but maybe learn to come out the other side as improved beings with a better understanding of how to tend to the needs and feelings of ourselves and others, and a renewed realization of our connectedness to nature and the rest of the world, as well as of what is truly most important to us.

Jessica Warren is co-founder of Mind: Unlocked a mental well-being business that provides practical tools, courses and workshops to help people cope with the stress of everyday modern life. She has been featured as a wellness speaker on BBC Radio and at conferences like Wanderlust and Eurekafest; and writes for Thrive Global, Economia Magazine, and the StartUp and P.S. I Love You publications on Medium. Jessica trained as a Chartered Accountant and worked in corporate finance, before deciding to dedicate her time to exploring and sharing how to live more fulfilling lives we love.

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10 Habits to Transform Your Mindset During Lockdown - Thrive Global

Why 2018-19 St. Louis Blues Were The Perfect Team To End Drought – Bleedin’ Blue

BOSTON, MASSACHUSETTS - JUNE 12: The St. Louis Blues celebrate after defeating the Boston Bruins in Game Seven to win the 2019 NHL Stanley Cup Final at TD Garden on June 12, 2019 in Boston, Massachusetts. (Photo by Patrick Smith/Getty Images)

When the St. Louis Blues hoisted the Stanley Cup for the first time in franchise history on June 12, 2019, they erased over 50 years of painful memories in one fell swoop. While few expected them to win it, they were actually the perfect team to win it for St. Louis.

When you consider the teams history, they dont have the longevity of teams like Chicago or Boston or Montreal. However, they have had their fair share of big names and good teams.

The Blues were not part of the Original Six, so they were not loaded with Hall of Fame talent like a Bobby Hull or Gordie Howe for years on end. Nevertheless, they had some great names.

While some were at the ends of their careers like Glenn Hall and Jacques Plante, there were plenty of up and comers like Garry Unger (who joined the team at 23), Curtis Joseph or Doug Gilmour.

It is true that most people only think of Brett Hull when they think of the Blues. If youve lived in St. Louis, obviously Bernie Federko gets thrown into that discussion as the best to wear the Note.

Nevertheless, the Blues have had tons of great names come through, whether for a cup of coffee or for long stretches. Theyve had Wayne Gretzky, Brendan Shanahan, Chris Pronger, Al MacInnis, Adam Oates, Pierre Turgeon, Red Berenson, Martin Brodeur, Scott Stevens, Grant Fuhr and more.

All those great names, many in the Hall of Fame, and none could bring the Blues to the promised land. Some were great goal scorers and put up unbelievable point totals, but the team as a whole was always missing something.

While we will always remember the 2019 team, there an argument to be made that other squads had more talent in past years.

In 1999-00, the Blues won the Presidents Trophy for the best record in the league. That team lacked scoring depth and had a goaltender that was amazing in the regular season and cost them everything in the playoffs.

In 1995-96, weve documented the pain that season caused. The team was actually under .500 that season, but you figured adding the leagues biggest name was going to bring great things that season or the next. Unfortunately, Mike Keenan happened.

The Blues had two 100-plus point scorers in 1990-91, a future Hall of Fame defender that won three Stanley Cups in New Jersey and decent goaltending. Fate had other plans as the Blues lost in the second round to the eventual finalist Minnesota North Stars.

The Blues built off their Presidents Trophy team and went to the conference final in 2001. They ran into a buzzsaw in eventual champions, the Colorado Avalanche.

St. Louis had a fantastic run in 2015-16. Early failings in putting teams away left them with no gas to beat San Jose.

So how did the Blues win it in 2019? They had zero 80-point scorers.

The last time that happened was in 2013-14. Not coincidentally, the L.A. Kings played a very heavy style, just like the Blues in 2019.

If you strip everything away though, the Blues won because they played as a team. The championship team had very good players, but nobody that was looked at to lead anytime anything went wrong.

Nobody would doubt that Vladimir Tarasenko was that teams best goal scorer. The Blues finally stopped asking him to be the only one to put the puck in the net every night.

Nobody was looking to a Scott Stevens-like defender to do all the heavy lifting. Colton Parayko and Jay Bouwmeester shut people down as a pairing.

The Blues would usually pair a more offensive defenseman with someone who took care of the other side more. That mixture gave everyone just the right responsibility and freedom, which often gives them the confidence to thrive in all three zones.

Add into the mix that Jordan Binnington played out of his mind that playoff run. His stats dont reflect it because he had several games when he was human, but he was superhuman more often than not and the NHL is the one sport when one hot player as a goaltender can win the whole thing.

Even then, the Blues did not rely completely on Binnington and nothing else. There was always someone that came up big.

If the top six had a slow start, the bottom six played with energy and either chipped in with a goal or stifled the opponent until the big guns got their legs. If the defense had a hiccup, Binnington picked them up.

When Binnington was slightly off, the offense either came up with a big goal or the defense blocked shots. And the Blues just hit, hit, hit. From a numbers point of view, they might not have had a record number of checks, but they punished every single opponent and wore them out.

It all boils down to the entire team pitching in. They were not looking to a Hull to lead the way or a Gretzky to save the day. The guys that played one or two games had as big a role in those one or two games as the guys that played all 26.

St. Louis legitimately rolled four lines that could score, hit, pester and provide energy. While you had your shutdown duo, the Blues felt no trepidation by any defensive pair going out there against the other teams best lines.

That is something rare, but something you often see in todays games winners. Stanley Cup champions are deep teams that just have that extra will and get a few bounces.

That cant be overlooked either. So many years in the past, there was that bounce that went against the Blues and it took the wind out of their sails completely.

The team that finally won it for St. Louis got a few bounces that never went their way in the past remember Ben Bishop almost losing his head off Paraykos shot? or they managed to not let any bad bounce take them out of it. *Coughhandpasscough*

In the end, by however you want to measure it, the Blues earned it in 2019 instead of just wanting it. There were better players in the Blues sweater in years past and there might have been better teams.

None could get it done. The guys finally did one year ago and now theyll be legends in the Gateway City forever.

More here:
Why 2018-19 St. Louis Blues Were The Perfect Team To End Drought - Bleedin' Blue

Al Southwick: Thought of living to 150 leaves me with mixed emotions – Worcester Telegram

Since my 80th birthday 20 years ago, I have been inundated by a flood of information about the elderly and their needs. Old age or at least anti-aging has become a cottage industry online, on television, in magazines, wherever. I thought I was pretty much inured to all that.

But now there is something new to think about. The Wall Street Journal recently published a piece on living to be 150. Rather, it published two pieces one by an epidemiologist predicting that it will happen in the next 75 years, and the second by a biologist who thinks that it wont. The two have wagered $300 apiece on the outcome, the payoff coming 75 years from now.

The possibility of living to 150 leaves me with mixed emotions, to put it mildly. I will hit 100 in a few weeks, a milestone long thought to be impressive. According to the New England Centenarian Study at Boston University, there are an estimated 343,000 folks over 100 living on the globe today, 80,000 in the United States, 800 in New England. The U.S. figures include 32,000 who are over 105. A United Nations study predicts there will be 3.2 million centenarians in 2050. Average life expectancy has jumped from 48 to 77 in the last century.

The New England Centenarian Study has been compiling statistics on old folks since 1995. It has three categories centenarians, semi-supercentarians (ages 105-109), and supercentarians (110 and up}. It now accepts only candidates who are 103 or over, so Im going to have to wait for a while. Among other findings, it has concluded that longevity is largely genetic. That figures. My older sister checked out at 103, most of my other siblings in their 90s or late 80s.

Ill admit that over the past 20 years or so I sometimes wondered if I would reach the century mark. I regarded it as a sort of goal. Now that Im on the threshold, I feel reasonably content and satisfied. I dont seem to have a goal say 105 in the same way that I used to. Why not? If I looked forward to reaching 90 when I hit 80 and to 100 when I reached 90, why would I not now anticipate 105 as my next goal?

The answer is complicated and involves subtle psychological and emotional factors. The fact is that I want to be realistic. The five years since my 95th birthday have been more difficult than the preceding five. Anyone who approaches the century mark has experienced various difficulties, physical and emotional. These do not diminish with passing of time. Anything but.

I say this as someone who has enjoyed extraordinary luck throughout my life. I got through four years of war in the Navy without a scratch. Ive had two remarkably fulfilling marriages and a satisfying career. Now, in my declining years, I have a cluster of relatives children, nieces, nephews and friends who do much to make my life a pleasing and productive experience. I cant praise them enough. The coronavirus has limited my visitor list, but I still communicate by phone and Skype with those I care about. Life is still worth living, despite the various handicaps of old age. I still enjoy it.

Tremendous advances have been made in human health since I was born. A baby girl born this week can expect to reach 80, a baby boy a bit less. On the average. Thats a huge increase over such expectations in 1920. Many diseases, once killers, have been eliminated, and the quality of life for us seniors has improved greatly, but there are limits. The agng process continues its relentless way. The centenarian study folks find that the upper limit of longevity may be 115 or thereabouts. Thats if everything everything goes right for a century or more.

I sometimes have to remind my caregivers that a 1920 model human or automotive needs constant maintenance. Its something we oldies just have to live with.

Now lets get on with it.

Originally posted here:
Al Southwick: Thought of living to 150 leaves me with mixed emotions - Worcester Telegram

In appreciation of Shirley Knight, an acting model for others – Brownwood Bulletin

Luminous is an overused word in theater criticism, but the word is aptly applied to Shirley Knight, the Tony- and Emmy-winning actress who died at age 83 on April 22 in San Marcos.

Knights daughter, Kaitlin Hopkins, founded the musical theater program at Texas State University. Although she maintained a residence in Los Angeles, Knight was a presence on the campus. She died of natural causes at Hopkins home.

A product of the Actors Studio heyday, she is linked to those method stars who may have burned brighter but probably not as consistently. There was never a part, small or star, she didn't illuminate from the inside out.

After receiving an Oscar nomination for her performance in "The Dark at the Top of the Stairs," in which she played a teenager while in her mid-20s, Knight was cast as Heavenly Finley in the 1962 film version of Tennessee Williams' "Sweet Bird of Youth," directed by Richard Brooks. Her beauty had a celestial quality that might have seemed to earn her the part. But there was more to the actress than Hollywood glamour. There were contradictions worthy of a Williams heroine. Her Heavenly combined porcelain fragility with bitter strength. The movie belonged to Geraldine Page and Paul Newman, but Knight's Heavenly clarified the drama's tragic stakes.

In his book "A Method to Their Madness: The History of the Actors Studio," Foster Hirsch captured the vital paradox that was Knight's presence: "Blonde, with dainty features and a translucent complexion, she might have become the conventional ingenue, playing a string of decorative roles. But anger churned beneath that pretty facade, and a sour expression a stingy smile tinged with irony promised thunder."

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She was committed to the work of acting, to uncovering the grit of her characters, to revealing the sand caught in the gears of the human machinery. She played Irina on Broadway in Anton Chekhov's "The Three Sisters" alongside Kim Stanley and Page in the Actors Studio production directed by Lee Strasberg, passing up the chance to be the Ophelia opposite Richard Burton's Hamlet. Her loyalty was to the community that had inspired her.

Knight, who won a Tony in 1976 for her performance in Robert Patrick's "Kennedy's Children," was a throwback to an era when acting was upheld as a rigorous discipline of craft and soul. Her career had longevity because it was predicated not on great looks but on her searching humanity.

Age, in addition to adding to her trove of Emmys (including one for HBO docudrama "Indictment: The McMartin Trial"), opened up possibilities. Twice I saw her onstage in her later years, once in Horton Foote's "The Young Man From Atlanta," in which she was nominated for a Tony for a performance so suffused with detailed life that it was astonishing such a feat of naturalism could be pulled off with so little fuss. She understood the denial of the grieving mother she played down to the brand of hairspray stiffening her coiffure. It was a performance that transformed abstract psychology into unadulterated behavior.

Almost as impressive was the way Knight, working discreetly off-Broadway in Deborah Grimberg's largely forgettable "Cycling Past the Matterhorn," endowed a playwriting doddle with intricate layers of felt experience. When I reviewed the play for the Village Voice in 2005, I commented on Knight's gift for never revealing "more than what's needed, though always more than you'd expect."

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In eulogizing Knight, I can't help thinking of her eulogy for Kim Stanley. I have a copy of the email that was read at the Actors Studio in New York in October 2001, when the city was still reeling from the 9/11 terrorist attacks. During the morning of the memorial service, New York was awash in the fresh fear of an anthrax scare. I remember wondering if I should take the subway or walk the two miles uptown. I arrived on time via subway and was uplifted by Knight's words, which communicated the values to which she held fast throughout her magnificently modest career:

I first met Kim Stanley in 1964. I was chosen by Lee Strasberg to play Irina in the Actors Studio production of Chekhov's "The Three Sisters." Imagine my excitement to discover that I was to star (in my Broadway debut) with Kim Stanley and Geraldine Page as my sisters. It would be impossible to relate how important Kim was to me in my development as an actor. I had seen her in the play about Freud and thought she gave the most extraordinary performance. One night at the beginning of the run of "The Three Sisters," Kim received applause on her exit. She came off stage muttering, "Well, that will never happen again." After the performance I asked what she meant as I assumed all applause was a good thing. She said, "Honey, if they can put their hands together, they aren't feeling (crap)." It was a revelation to me that the object as an artist was to make the audience feel and to enlighten them and that applause in the middle of a dramatic play was stopping the journey. She was always kind and loving to me as well. Another night during the run I picked up a piece of broken glass from the floor where I knew she would be kneeling. She clasped my hand and it began to bleed. She did not for a moment come out of the play but simply and lovingly placed her handkerchief on the wound. She also took me to the hospital after for stitches. Every time I look at my right palm, I am reminded of Kim. Not that I need a wound to remind me I have the memory in my mind and heart of possibly the greatest American actress in the 20th century. With love, Shirley Knight.

Knight's performances on stage and screen have etched in our memories and hearts the example of an actor who unfailingly honored her art.

American-Statesman staff writer Michael Barnes contributed to this report.

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In appreciation of Shirley Knight, an acting model for others - Brownwood Bulletin

Once and for all: No, we didnt get the coronavirus from bats – Haaretz

Lets start from the punch line: Bats did not give us the latest coronavirus. Nor were its notorious cousins SARS-1 or MERS, or even the ebola virus, transmitted from bats to humans. So what did happen?

A distant relative of the current coronavirus, SARS-CoV-2, was isolated in a bat in China. Genetic analyses that looked for similarity between the virus in the bat and SARS-CoV-2, and factored in the theoretical pace at which the virus mutates, estimated that the two viruses parted ways between five and 50 years ago. In other words, one possibility is that about five years ago, the bat coronavirus managed to infect some other different animal we dont know which one at this time. In that next animal, the coronavirus lived and mutated over those five years, and one day infected a human for the first time. There are other hypotheses as well.

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Science doesnt yet know where the coronavirus lurked in wait for the past few years, or when it became dangerous to people, or when the first person was infected, nor do we know which animal infected that first human. The only thing science knows for sure is that the coronavirus isolated from the Chinese bat cannot have infected humans and isnt dangerous to them.

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This fact was published two months ago, based on the genetic sequences of the bat and human viruses. This is also true in the cases of SARS, MERS and ebola despite repeated efforts to locate these viruses in bats, all that researchers found were similar viruses, or evidence of previous exposure that doesnt mean they carried the virus routinely and certainly not that they passed it to humans, despite reports that have appeared in the general press (including in Haaretz Hebrew edition, on April 19).

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Why do bats get such bad press in connection with viruses? In recent years there have been increasingly strident claims that bats carry zoonotic viruses, which can infect humans. But there are serious scientists who disagree with this and argue that bats are no different than other mammals in the number of zoonotic viruses that they carry, certainly if you consider the large number of species in the bat family. Around a fifth of all the worlds mammals are bats.

There are several batty characteristics that render them suspect when it comes to viruses. Their ability to fly, their presence in all parts of the world, their large colonies and the crowding in which they live; their long lives; and their proximity to humans all make them ostensibly suited to transmitting diseases.

The fact that they are mammals increases the chance of their being transmitters. This is why searching for new viruses in bats has become almost a fad among researchers; and the more in-depth the search, the more likely something will be found.

Moreover, accumulated findings show that the bat immune system is unique among mammals, and skilled in dealing with viruses. This immune system enables bats to fend off viruses, including deadly ones, by means of a moderate inflammation response that leads to immunity. As a result, many studies find antibodies in bats proof that theyve been exposed to viruses without finding the virus itself.

Without the live virus itself, the bat cannot be a carrier and certainly cant be a transmitter. This means that the important link in the chain of zoonotic transmission to humans is still missing.

Eating a bat when it is sick could cause infection, just like eating any other sick animal could, and is not recommended. As a general rule, to reduce the chance of zoonotic transmission of viruses from bats or any other animals, its best to eat them infrequently and in general to minimize encounters with them; to let them live in their natural environments and stop invading their habitats.

Its interesting to note that the amazing bat immune system apparently developed to support its unusual way of life. Bats live longer than almost any other mammals. In 2006 a Brandts bat (Myotis brandtii), weighing a mere 7 grams and about the size of your finger, was recaptured after it had been tagged by scientists in Siberia 41 years before! A mouse of similar size wouldnt live for more than two years. Such extreme longevity requires an optimal immune system.

Bats flying ability, unique among mammals, seems to have also contributed to the development of its immune system. In our studies weve found that small bats weighing no more than 30 grams can fly a distance of more than 250 kilometers in a night. The energy needs and accelerated metabolism during flight are accompanied by oxidative damage, which requires an appropriate immune system. Some believe this immune system is why bats very rarely develop cancer.

In addition, a bat who leaves its cave in the evening raises its body temperature by a few degrees within a minute. This elevated body temperature, which reaches 40 degrees Celsius or more, apparently helps kill undesirable viruses and bacteria.

Its important to stress that our love for bats hasnt blinded us (bats arent blind either, by the way). There are zoonotic viruses that are transmitted by bats such as Marburg, Hendra, Nipah and bat rabies, none of which are found in Israel. Bat viruses should be accorded the respect they deserve, but theres no reason to credit bats with viruses that arent theirs.

Prof. Yovel and Dr. Weinberg teach in the zoology department of Tel Aviv Universitys life sciences faculty.

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Once and for all: No, we didnt get the coronavirus from bats - Haaretz

Theres a New Healthy, High Protein Vegan Meat Designed for Flexitarians – LIVEKINDLY

Consumers are becoming increasingly more aware of how their food choices impact the environment and their health.

Research shows the consumption of animal products, like processed and red meat, increases the risk of certain health issues. These include heart disease, stroke, and diabetes. One study out of the University of California, Davis, found 75 percent of people have considered giving up meat for their health.

In lieu of animal products, many consumers are opting for less meat in favor of healthier, plant-based proteins. Los Angeles-based company Longve is one brand thats harnessing the power of plants to make healthier meats.

The companys CEO, Douglas Kantner, says turning 50 was a major catalyst in his health journey and ultimately inspired the companys mission and concept.

Ive always been interested in health and fitness, and have been a lifelong athleteI played football in college, he said. But when I hit 50, I found myself becoming more and more interested in what I could do to prolong my longevity.

Longve, which is a play on longevity, is revolutionizing the clean-eating market with its debut products: Gluten-Free Breadless Crumbs and Plant-Based Protein Crumblesboth of which are made from 100 percent sustainable pea protein.

Founded in 2019, Longve set out to create innovative, plant-based foods that aligned with consumers desire for good health, overall wellness, and longevity for not only themselves but for the planet, too.

With the tagline Eat for a Better Tomorrow, Today, Longve developed the worlds first shelf-stable, plant-based meat crumbles using pure-plant ingredients.

After working in the food industry for more than 30 years I decided to use my industry experience to find ways to help people find a way to put more plants on their plates, Kantner explained.

He continued, I wanted them to actually enjoy products that were plant-based, clean label and had nutritional value in a way that was more pleasurable than punishing, while also keeping an eye on planet sustainability.

The plant-based demographic has greatly expanded as more people adopt flexible eating habits. Health concerns, as well as environmental factors, have driven the popularity of the flexitarian diet.

Flexitarianismalso called the semi-vegetarian dietpromotes the consumption of plant-based foods. A flexitarian diet typically consists of vegetables, fruits, legumes, and whole grains. But it isnt as strict as vegetarian and vegan diets. So, proponents of flexitarianism may still eat animal products like meat and fish, but only in moderation.

Along with wanting to create foods that are healthy and good for the planet, the notion of flexible eating also inspires the Longve team. But they believe the definition of flexitarianism should expand to include people who simply want to eat more vegetables.

Although the companys products are plant-based, it doesnt just cater to non-meat eaters. It says it made its products to support all dietary choices and lifestyles. One of its missions is to help people achieve their health goals in the cleanest, most efficient way possible.

Longves goal is to help people easily transition to eating more plant-based foodsa goal that Kantner says the companys clean, healthy products will help them achieve.

All of our products are clean label and made with minimal ingredients and no additives. We use 100-percent sustainable pea protein as the sole ingredient in our Plant-based Protein Crumbles and Plant-Based Breadless Crumbs, and were extremely proud of the fact that theyre Project Non-GMO Certified, Certified Gluten-Free, NSF-certified Plant-Based, and soy-free, he said. That makes them one of the cleanest meat replacements on the market, and a great foundation for any flexitarian diet.

Pea protein is becoming increasingly more popular amongst manufacturers like Longve because the protein source is plant-based, better for the environment, and more economical to produce.

Pea protein is obtained from ground yellow split peas. It is a more favorable plant-based protein source because it doesnt contain common food allergens like soy or wheat. It also features a good profile of nutrients like fiber, folate, manganese, phosphorus, niacin, and copper.

Pea protein is also a complete protein. This is because it contains all nine amino acids that are essential for the human diet.

Longves plant-based ground crumbles not only taste realistic but have a similar texture to traditional ground meat.

The reaction to our Original Plant-based Protein Crumbles [has been] incrediblelots of people love the fact that [the crumbles] neutral flavor makes them a great base for their favorite recipes, Kantner said.

The CEO explained that the favorable response to the original crumbles led the company to launch two new flavors. They also created a Chopped Protein product designed to replace chopped poultry and pork in recipes.

We did, however, have lots of requests for flavored crumbles that would make it even easier to get dinner on the table during busy weeknights. Were really excited to [introduce] two flavored crumblesMasala Curry and Fiesta Tacolater this summer. Both [crumbles] come with seasoning packets to make preparation a snap. We will also be launching Chopped Protein which will replace white meats like Turkey and Pork, he said.

If the companys Instagram is anything to go by, its products are extremely versatile. It showcases the Plant-Based Protein Crumbles in a variety of dishes. These include chilis, enchilada lasagnas, tacos, and meaty spaghetti, to name a few

Chef Lee Gross says the products ease of use makes adding high-quality plant protein into dishes a breeze.

[The crumbles] can be used in a virtually endless range of applications, adaptable to almost any cuisine or cooking style I can think of. Prep is a breeze, requiring only a quick soak to be recipe-ready with a distinctive, meat-like texture, and can even be used straight from the bag in dishes such as soups and stews, he said.

The crumbles also stack up well to ground beef. One six-ounce bag of Plant-Based Protein Crumbles offers roughly the equivalent of three pounds of traditional ground meat. The crumbles also feature a high protein content. A single serving of Longves nutritious, pea protein-based Original variety contains 40 grams of protein. The Fiesta Taco and Masala Curry crumbles contain 41 and 44 grams of protein per serving, respectively.

Longves three varieties of shelf-stable Plant-Based Protein Crumbles are available to order on Amazon. Its Gluten-Free Breadless Crumbswhich come in two varieties: Panko and Plaincan also be purchased online.

To learn more about Longve, visit LongeveBrands.com.

This is a sponsored post.

Summary

Article Name

There's a New Healthy, High Protein Vegan Meat Designed for Flexitarians

Description

Flexitarians just got more vegan meat options. The plant-based company Longve is revolutionizing the clean-eating market using pea protein.

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Audrey Enjoli

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LIVEKINDLY

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Theres a New Healthy, High Protein Vegan Meat Designed for Flexitarians - LIVEKINDLY

These Lifelong Friends Just Launched a Line of Leather Goods – D Magazine

The story of luxury line Franki Ray begins three years ago, on a front porch around midnight. Stacey George and Sasha Spivey, lifelong best friends, had decided to start a company. Theyd already chosen the name Franki Ray (after their fathers) and bought the domain. They wanted to create something; they just needed to decide what, exactly, to create.

What should our email address be? Stacey George asked.

[emailprotected], Sasha Spivey suggested. And then, Spivey says, laughing as she tells the story over a glass of white wine, We just stop and look at each other and were like, Holywere going to make briefcases.

It was as simple as that. And after three years of incessant yet enjoyable toil, Spivey and George debuted a line of luxury leather briefcases, backpacks, duffel bags, jewelry rolls, and wallets last month.

Its rather a random story, really, unless you know George and Spivey. They met in kindergarten at St. Bernard of Clairvaux Catholic School, in Casa Linda, and graduated best friends from Bishop Lynch. Its almost as if our lives merged to where there wasnt a clear delineation of whose life was whose, George says. Its like, our friends. Im like, Im coming to get our dog.

They parted ways for college. George majored in political science and considered law school. Spivey majored in biomedical sciences and worked at a contract research lab, specializing in skincare; she then transitioned to plastic surgery, including laser resurfacing.

But one day, they just sat down, George recalls. Somebody said something about a bag [Spivey was] carrying, that I had given her. It was a gift bag, nothing special. [They asked,] Oh, are you guys, like making those? George laughs. I guess it looked homemade. So, were like, No, we dont make these bags. But we couldveand it would have been way better.

Which led to the brainstorming. Were sitting at my house trying to spitball a bunch of ideas to figure out what are we going to make first, Spivey says..

Neither Spivey nor George specialized in leather and manufacturing, but now they had a streamlined focus, as Spivey puts it, a target plan and idea. Theyd meet once or twice a week and sit at the kitchen table to talk about their plans and the progression. That evolved to daily texting and midnightly chats, atop their day jobs. They hadnt gone out in the past 10 months, Spivey claims, when they launched; rather, theyd sat at the kitchen table and ironed out their plans.

They used vision boards to create the bouquets and garlands that adorn the interiors of their briefcases, backpacks, and duffel bags. They photoshopped a farrago with one flower they loved, another flower they loved, a picture that inspired them, outlining the optimal color scheme and design aesthetic, then hired a professional artist to create an original computer graphic or hand-drawn image.

Spivey went so far as to create a prototypea three-dimensional vision board, if you will. She went to the thrift store, purchased old-school briefcases, spray-painted them, gutted them, and relined them with vibrant fabrics. She used the prototypes to convey Franki Rays aesthetic to the manufacturer they found after 32 rejections. Its that manufacturer who told them, We can also do other [products,] if you want. This is when the friends decided to do a whole collection: briefcases, backpacks, duffel bags, jewelry rolls, and wallets.

Despite the disparity in the shape and size of the products, certain themes crop up over and again. Robin egg blue is a favorite leather color. Roses are a favorite flower. (Theyre a nod to Abby, Spiveys biological and Georges adopted grandmother, who taught the best friends that femininity is strength). Lions are a favorite animal, appearing on the interior of briefcases and on the exterior of briefcases, jewelry rolls, and backpacks as clasps or keychains. The lion clasp equals seven months of work, the best friends nod gravely.

Its this commitment that defines Franki Ray. Spivey and George are committed to protecting the environment; hence, all leather is vegetable tanned and the bags microsuede interiors are printed with water-based pigments. Durability is equally important to the two, and all bags are made with full-grain leather, which retains the skins thick epidermis. Briefcases are made with buffalo leather, which is three times the thickness of cowhide, so that theyre tougher and more resilient. Each bag is hand-polished and rubbed with an emollient to protect against water and increase longevity. Every bag is handmade in India.

The attention to detail really [represents] our friendship, Spivey says. Were particular. We like hanging out with each other for very specific reasons and have continued to do so our whole lives because we still enjoy it.

When asked about how they anticipate the new bags will handle and hold up to daily use, Spivey and George had a good laugh. Maybe dont take it hiking in the wilderness when its snowing, George said. Added Spivey, From general human interaction with something thats nice, they should last you I dont want to say a lifetime, but maybe.

Dont tie it to your trunk like a Just Married can, she laughed. But the symbolism might be fitting. After all, says Spivey, Everything we create is a union of us.

Shop their latest styles at frankiray.com.

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These Lifelong Friends Just Launched a Line of Leather Goods - D Magazine

Global Precision Medicine Software Industry, Forecast to 2027 – Includes Growth Strategies and Competitive Benchmarking of Key Players -…

DUBLIN--(BUSINESS WIRE)--The "Precision Medicine Software Market by Delivery Mode (On-premise, Cloud-based), Application (Oncology, Pharmacogenomics, CNS), End User (Healthcare Providers, Research, Academia, Pharma, Biotech) - Global Forecast to 2027 " report has been added to ResearchAndMarkets.com's offering.

The global precision medicine software market is expected to grow at a CAGR of 11.8% from 2019 to 2027 to reach $2.8 billion by 2027.

The growth in the precision medicine software market is mainly attributed to the factors such as paradigm shift in treatment, rising pressure to decrease healthcare costs, scientific & technological advances in the genomics field, and growing focus towards providing companion diagnostics & biomarkers for various therapeutic areas. Moreover, emerging countries and AI in precision medicine provides significant growth opportunities for players operating in the precision medicine software market.

The precision medicine software market study presents historical market data in terms of value (2017, and 2018), current data (2019), and forecasts for 2027 - by delivery mode, application, and end user. The study also evaluates industry competitors and analyzes the market at regional and country level.

On the basis of delivery mode, the on-premise segment accounted for the largest share of the overall precision medicine software market in 2019. However, the web & cloud-based delivery mode segment is expected to grow at the faster CAGR during the forecast period, owing to its benefits, such as on-demand self-serving, no maintenance cost, low storage & upfront cost, and excessive storage flexibility. In addition, the factors such as greater security in private clouds and automated updating features of web and cloud solutions are further expected to support the rapid growth of this segment.

Based on application, the oncology segment accounted for the largest share of the overall precision medicine software market in 2019. However, the pharmacogenomics segment is expected to witness rapid growth during the forecast period. The factors such as increasing incidence of adverse drug reaction, growing focus on genomic-based study, shift from one-size-fits-all approach to personalized approach, and rising pressure on pharmaceutical companies to develop new drugs promote the fastest growth of this segment.

Based on end user, the healthcare providers segment commanded the largest share of the overall precision medicine software market in 2019. However, the pharmaceutical & biotechnological companies segment is expected to witness rapid growth during the forecast period. The factors such as increasing R&D activities related to precision medicine, increasing collaboration between pharma & biotech companies and software vendors, shift from conventional one-size-fits-all-type treatment to precision treatment, and rising R&D costs are the major factors driving rapid growth of this segment.

An in-depth analysis of the geographical scenario of the precision medicine software market provides detailed qualitative and quantitative insights about the five major geographies (North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa) along with the coverage of major countries in each region.

North America commanded the largest share of the global precision medicine software market in 2019, followed by Europe, Asia-Pacific, Latin America, and the Middle East & Africa. The factors such as well-established healthcare system in the region, rising adoption of technologically advanced products for cancer diagnosis & treatment, growing HCIT investment, government initiatives supporting developments in precision medicine, growing availability of research funding, and higher accessibility to precision medicine software are responsible for the largest share of North America in the precision medicine software market.

The key players operating in the global precision medicine software market are Syapse, Inc. (U.S.), Fabric Genomics, Inc. (U.S.), SOPHiA GENETICS SA (Switzerland), Human Longevity, Inc. (U.S.), Sunquest Information Systems Inc. (U.S.), LifeOmic Health, LLC (U.S.), Translational Software Inc. (U.S.), N-of-One (U.S.), Gene42 Inc. (Canada), PierianDx (U.S.), Foundation Medicine, Inc. (U.S.), and 2bPrecise (U.S.), among others.

Key Topics Covered

1. Introduction

1.1. Market Definition

1.2. Market Ecosystem

1.3. Currency

1.4. Key Stakeholders

2. Research Methodology

3. Executive Summary

4. Market Insights

4.1. Introduction

4.2. Drivers

4.2.1. Paradigm Shift in Treatment

4.2.2. Rising Pressure to Decrease Healthcare Costs

4.2.3. Scientific & Technological Advances in the Genomics Field

4.2.4. Growing Focus Towards Providing Companion Diagnostics (CDx) & Biomarkers

4.3. Restraints

4.3.1. Lack of Awareness about Precision Medicine Practices

4.3.2. Fragmented Healthcare Systems in Developing Countries

4.4. Opportunities

4.4.1. Emerging Economies

4.4.2. Artificial Intelligence in Precision Medicine

4.5. Challenge

4.5.1. Lack of Reimbursement for Genetic Testing & Precision Medicine

5. Global Precision Medicine Software Market, by Delivery Mode

5.1. Introduction

5.2. On-Premise

5.3. Web & Cloud-Based

6. Global Precision Medicine Software Market, by Application

6.1. Introduction

6.2. Oncology

6.3. Pharmacogenomics

6.4. Other Applications

7. Global Precision Medicine Software Market, by End User

7.1. Introduction

7.2. Healthcare Providers

7.3. Research and Government Institutes

7.4. Pharmaceutical & Biotechnology Companies

8. Geographic Analysis

8.1. Introduction

8.2. North America

8.2.1. U.S.

8.2.2. Canada

8.3. Europe

8.3.1. Germany

8.3.2. France

8.3.3. U.K.

8.3.4. Italy

8.3.5. Spain

8.3.6. Rest of Europe (RoE)

8.4. Asia-Pacific

8.4.1. Japan

8.4.2. China

8.4.3. India

8.4.4. Rest of Asia-Pacific (RoAPAC)

8.5. Latin America

8.6. Middle East and Africa

9. Competitive Landscape

9.1. Introduction

9.2. Key Growth Strategies

9.3. Competitive Benchmarking

10. Company Profiles

(Business Overview, Strategic Developments, Product & Service Offerings, Financial Overview)

10.1. 2bprecise LLC (Part of Allscripts Healthcare Solutions Inc.)

10.2. Pieriandx, Inc.

10.3. Gene42, Inc.

10.4. Foundation Medicine, Inc.

10.5. N-Of-One, Inc. (Part of Qiagen N.V.)

10.6. Translational Software, Inc.

10.7. Syapse, Inc.

10.8. Fabric Genomics, Inc.

10.9. Sophia Genetics S.A.

10.10. Human Longevity, Inc.

10.11. Sunquest Information Systems, Inc.

10.12. Lifeomic Health, LLC

For more information about this report visit https://www.researchandmarkets.com/r/igl2sf

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Adrenomyeloneuropathy Treatment Market Size, Key Trends, Challenges and Standardization, Research, Key Players, Economic Impact and Forecast to…

Complete study of the global Adrenomyeloneuropathy Treatment market is carried out by the analysts in this report, taking into consideration key factors like drivers, challenges, recent trends, opportunities, advancements, and competitive landscape. This report offers a clear understanding of the present as well as future scenario of the global Adrenomyeloneuropathy Treatment industry. Research techniques like PESTLE and Porters Five Forces analysis have been deployed by the researchers. They have also provided accurate data on Adrenomyeloneuropathy Treatment production, capacity, price, cost, margin, and revenue to help the players gain a clear understanding into the overall existing and future market situation.

Key companies operating in the global Adrenomyeloneuropathy Treatment market include _:, Ascend Biopharmaceuticals, Novadip Biosciences, Eureka Therapeutics, Human Longevity, Regeneus, Allogene Therapeutics, BioRestorative Therapies, Immatics Biotechnologies, NewLink Genetics, Cytori Therapeutics, Talaris Therapeutics

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Segmental Analysis

The report has classified the global Adrenomyeloneuropathy Treatment industry into segments including product type and application. Every segment is evaluated based on growth rate and share. Besides, the analysts have studied the potential regions that may prove rewarding for the Adrenomyeloneuropathy Treatment manufcaturers in the coming years. The regional analysis includes reliable predictions on value and volume, thereby helping market players to gain deep insights into the overall Adrenomyeloneuropathy Treatment industry.

Global Adrenomyeloneuropathy Treatment Market Segment By Type:

, Steroid Replacement Therapy, Stem Cell Transplant By the end users,

Global Adrenomyeloneuropathy Treatment Market Segment By Application:

Since the COVID-19 virus outbreak in December 2019, the disease has spread to almost 100 countries around the globe with the World Health Organization declaring it a public health emergency. The global impacts of the coronavirus disease 2019 (COVID-19) are already starting to be felt, and will significantly affect the Adrenomyeloneuropathy Treatment market in 2020. COVID-19 can affect the global economy in three main ways: by directly affecting production and demand, by creating supply chain and market disruption, and by its financial impact on firms and financial markets. The outbreak of COVID-19 has brought effects on many aspects, like flight cancellations; travel bans and quarantines; restaurants closed; all indoor events restricted; over forty countries state of emergency declared; massive slowing of the supply chain; stock market volatility; falling business confidence, growing panic among the population, and uncertainty about future. This report also analyses the impact of Coronavirus COVID-19 on the Adrenomyeloneuropathy Treatment industry. Based on our recent survey, we have several different scenarios about the Adrenomyeloneuropathy Treatment YoY growth rate for 2020. The probable scenario is expected to grow by a xx% in 2020 and the revenue will be xx in 2020 from US$ xx million in 2019. The market size of Adrenomyeloneuropathy Treatment will reach xx in 2026, with a CAGR of xx% from 2020 to 2026. Global Adrenomyeloneuropathy Treatment market: Drivers and Restraints This section covers the various factors driving the global Adrenomyeloneuropathy Treatment market. To understand the growth of the market it is important to analyze the various drivers present the market. It provides data by value and volume of different regions and their respective manufacturers. This data will elaborate on the market share occupied by them, predict their revenue concerning strategies, and how they will grow in the future. After explaining the drivers, the report further evaluates the new opportunities and current trends in the market. Market restraints are factors hampering market growth. Studying these factors is equally pivotal as they help a reader need understand the weaknesses of the market. Global Adrenomyeloneuropathy Treatment market: Segment Analysis The global Adrenomyeloneuropathy Treatment market is split into two segments, type, and application. The product type briefs on the various types of products available in the market. The report also provides data for each product type by revenue for the forecast time period. It covers the price of each type of product. The other segment on the report, application, explains the various uses of the product and end-users. In the report, the researchers have also provided revenue according to the consumption of the product. Global Adrenomyeloneuropathy Treatment market: Regional Analysis The major regions covered in the report are North America, Europe, China, Rest of Asia Pacific, Central & South America, Middle East & Africa, etc. It includes revenue analysis of each region for the year 2015 to 2026. Global Adrenomyeloneuropathy Treatment market: Key Players The report lists the major players in the regions and their respective market share on the basis of global revenue. It also explains their strategic moves in the past few years, investments in product innovation, and changes in leadership to stay ahead in the competition. This will give the reader an edge over others as a well-informed decision can be made looking at the holistic picture of the market. By the therapy, the market is primarily split into, Steroid Replacement Therapy, Stem Cell Transplant By the end users, Hospitals, Clinics, Ambulatory Surgical Centers, Others

Competitive Landscape

It is important for every market participant to be familiar with the competitive scenario in the global Adrenomyeloneuropathy Treatment industry. In order to fulfil the requirements, the industry analysts have evaluated the strategic activities of the competitors to help the key players strengthen their foothold in the market and increase their competitiveness.

Key companies operating in the global Adrenomyeloneuropathy Treatment market include _:, Ascend Biopharmaceuticals, Novadip Biosciences, Eureka Therapeutics, Human Longevity, Regeneus, Allogene Therapeutics, BioRestorative Therapies, Immatics Biotechnologies, NewLink Genetics, Cytori Therapeutics, Talaris Therapeutics

Key questions answered in the report:

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TOC

1 Market Overview of Adrenomyeloneuropathy Treatment1.1 Adrenomyeloneuropathy Treatment Market Overview

1.1.1 Adrenomyeloneuropathy Treatment Product Scope

1.1.2 Market Status and Outlook1.2 Global Adrenomyeloneuropathy Treatment Market Size Overview by Region 2015 VS 2020 VS 20261.3 Global Adrenomyeloneuropathy Treatment Market Size by Region (2015-2026)1.4 Global Adrenomyeloneuropathy Treatment Historic Market Size by Region (2015-2020)1.5 Global Adrenomyeloneuropathy Treatment Market Size Forecast by Region (2021-2026)1.6 Key Regions Adrenomyeloneuropathy Treatment Market Size YoY Growth (2015-2026)

1.6.1 North America Adrenomyeloneuropathy Treatment Market Size YoY Growth (2015-2026)

1.6.2 Europe Adrenomyeloneuropathy Treatment Market Size YoY Growth (2015-2026)

1.6.3 China Adrenomyeloneuropathy Treatment Market Size YoY Growth (2015-2026)

1.6.4 Rest of Asia Pacific Adrenomyeloneuropathy Treatment Market Size YoY Growth (2015-2026)

1.6.5 Latin America Adrenomyeloneuropathy Treatment Market Size YoY Growth (2015-2026)

1.6.6 Middle East & Africa Adrenomyeloneuropathy Treatment Market Size YoY Growth (2015-2026)1.7 Coronavirus Disease 2019 (Covid-19): Adrenomyeloneuropathy Treatment Industry Impact

1.7.1 How the Covid-19 is Affecting the Adrenomyeloneuropathy Treatment Industry

1.7.1.1 Adrenomyeloneuropathy Treatment Business Impact Assessment Covid-19

1.7.1.2 Supply Chain Challenges

1.7.1.3 COVID-19s Impact On Crude Oil and Refined Products

1.7.2 Market Trends and Adrenomyeloneuropathy Treatment Potential Opportunities in the COVID-19 Landscape

1.7.3 Measures / Proposal against Covid-19

1.7.3.1 Government Measures to Combat Covid-19 Impact

1.7.3.2 Proposal for Adrenomyeloneuropathy Treatment Players to Combat Covid-19 Impact 2 Adrenomyeloneuropathy Treatment Market Overview by Therapy2.1 Global Adrenomyeloneuropathy Treatment Market Size by Therapy: 2015 VS 2020 VS 20262.2 Global Adrenomyeloneuropathy Treatment Historic Market Size by Therapy (2015-2020)2.3 Global Adrenomyeloneuropathy Treatment Forecasted Market Size by Therapy (2021-2026)2.4 Steroid Replacement Therapy2.5 Stem Cell Transplant 3 Adrenomyeloneuropathy Treatment Market Overview by Therapy3.1 Global Adrenomyeloneuropathy Treatment Market Size by End Users: 2015 VS 2020 VS 20263.2 Global Adrenomyeloneuropathy Treatment Historic Market Size by End Users (2015-2020)3.3 Global Adrenomyeloneuropathy Treatment Forecasted Market Size by End Users (2021-2026)3.4 Hospitals3.5 Clinics3.6 Ambulatory Surgical Centers3.7 Others 4 Global Adrenomyeloneuropathy Treatment Competition Analysis by Players4.1 Global Adrenomyeloneuropathy Treatment Market Size (Million US$) by Players (2015-2020)4.2 Global Top Manufacturers by Company Type (Tier 1, Tier 2 and Tier 3) (based on the Revenue in Adrenomyeloneuropathy Treatment as of 2019)4.3 Date of Key Manufacturers Enter into Adrenomyeloneuropathy Treatment Market4.4 Global Top Players Adrenomyeloneuropathy Treatment Headquarters and Area Served4.5 Key Players Adrenomyeloneuropathy Treatment Product Solution and Service4.6 Competitive Status

4.6.1 Adrenomyeloneuropathy Treatment Market Concentration Rate

4.6.2 Mergers & Acquisitions, Expansion Plans 5 Company (Top Players) Profiles and Key Data5.1 Ascend Biopharmaceuticals

5.1.1 Ascend Biopharmaceuticals Profile

5.1.2 Ascend Biopharmaceuticals Main Business and Companys Total Revenue

5.1.3 Ascend Biopharmaceuticals Products, Services and Solutions

5.1.4 Ascend Biopharmaceuticals Revenue (US$ Million) (2015-2020)

5.1.5 Ascend Biopharmaceuticals Recent Developments5.2 Novadip Biosciences

5.2.1 Novadip Biosciences Profile

5.2.2 Novadip Biosciences Main Business and Companys Total Revenue

5.2.3 Novadip Biosciences Products, Services and Solutions

5.2.4 Novadip Biosciences Revenue (US$ Million) (2015-2020)

5.2.5 Novadip Biosciences Recent Developments5.3 Eureka Therapeutics

5.5.1 Eureka Therapeutics Profile

5.3.2 Eureka Therapeutics Main Business and Companys Total Revenue

5.3.3 Eureka Therapeutics Products, Services and Solutions

5.3.4 Eureka Therapeutics Revenue (US$ Million) (2015-2020)

5.3.5 Human Longevity Recent Developments5.4 Human Longevity

5.4.1 Human Longevity Profile

5.4.2 Human Longevity Main Business and Companys Total Revenue

5.4.3 Human Longevity Products, Services and Solutions

5.4.4 Human Longevity Revenue (US$ Million) (2015-2020)

5.4.5 Human Longevity Recent Developments5.5 Regeneus

5.5.1 Regeneus Profile

5.5.2 Regeneus Main Business and Companys Total Revenue

5.5.3 Regeneus Products, Services and Solutions

5.5.4 Regeneus Revenue (US$ Million) (2015-2020)

5.5.5 Regeneus Recent Developments5.6 Allogene Therapeutics

5.6.1 Allogene Therapeutics Profile

5.6.2 Allogene Therapeutics Main Business and Companys Total Revenue

5.6.3 Allogene Therapeutics Products, Services and Solutions

5.6.4 Allogene Therapeutics Revenue (US$ Million) (2015-2020)

5.6.5 Allogene Therapeutics Recent Developments5.7 BioRestorative Therapies

5.7.1 BioRestorative Therapies Profile

5.7.2 BioRestorative Therapies Main Business and Companys Total Revenue

5.7.3 BioRestorative Therapies Products, Services and Solutions

5.7.4 BioRestorative Therapies Revenue (US$ Million) (2015-2020)

5.7.5 BioRestorative Therapies Recent Developments5.8 Immatics Biotechnologies

5.8.1 Immatics Biotechnologies Profile

5.8.2 Immatics Biotechnologies Main Business and Companys Total Revenue

5.8.3 Immatics Biotechnologies Products, Services and Solutions

5.8.4 Immatics Biotechnologies Revenue (US$ Million) (2015-2020)

5.8.5 Immatics Biotechnologies Recent Developments5.9 NewLink Genetics

5.9.1 NewLink Genetics Profile

5.9.2 NewLink Genetics Main Business and Companys Total Revenue

5.9.3 NewLink Genetics Products, Services and Solutions

5.9.4 NewLink Genetics Revenue (US$ Million) (2015-2020)

5.9.5 NewLink Genetics Recent Developments5.10 Cytori Therapeutics

5.10.1 Cytori Therapeutics Profile

5.10.2 Cytori Therapeutics Main Business and Companys Total Revenue

5.10.3 Cytori Therapeutics Products, Services and Solutions

5.10.4 Cytori Therapeutics Revenue (US$ Million) (2015-2020)

5.10.5 Cytori Therapeutics Recent Developments5.11 Talaris Therapeutics

5.11.1 Talaris Therapeutics Profile

5.11.2 Talaris Therapeutics Main Business and Companys Total Revenue

5.11.3 Talaris Therapeutics Products, Services and Solutions

5.11.4 Talaris Therapeutics Revenue (US$ Million) (2015-2020)

5.11.5 Talaris Therapeutics Recent Developments 6 North America Adrenomyeloneuropathy Treatment by Players and by End Users6.1 North America Adrenomyeloneuropathy Treatment Market Size and Market Share by Players (2015-2020)6.2 North America Adrenomyeloneuropathy Treatment Market Size by End Users (2015-2020) 7 Europe Adrenomyeloneuropathy Treatment by Players and by End Users7.1 Europe Adrenomyeloneuropathy Treatment Market Size and Market Share by Players (2015-2020)7.2 Europe Adrenomyeloneuropathy Treatment Market Size by End Users (2015-2020) 8 China Adrenomyeloneuropathy Treatment by Players and by End Users8.1 China Adrenomyeloneuropathy Treatment Market Size and Market Share by Players (2015-2020)8.2 China Adrenomyeloneuropathy Treatment Market Size by End Users (2015-2020) 9 Rest of Asia Pacific Adrenomyeloneuropathy Treatment by Players and by End Users9.1 Rest of Asia Pacific Adrenomyeloneuropathy Treatment Market Size and Market Share by Players (2015-2020)9.2 Rest of Asia Pacific Adrenomyeloneuropathy Treatment Market Size by End Users (2015-2020) 10 Latin America Adrenomyeloneuropathy Treatment by Players and by End Users10.1 Latin America Adrenomyeloneuropathy Treatment Market Size and Market Share by Players (2015-2020)10.2 Latin America Adrenomyeloneuropathy Treatment Market Size by End Users (2015-2020) 11 Middle East & Africa Adrenomyeloneuropathy Treatment by Players and by End Users11.1 Middle East & Africa Adrenomyeloneuropathy Treatment Market Size and Market Share by Players (2015-2020)11.2 Middle East & Africa Adrenomyeloneuropathy Treatment Market Size by End Users (2015-2020) 12 Adrenomyeloneuropathy Treatment Market Dynamics12.1 Industry Trends12.2 Market Drivers12.3 Market Challenges12.4 Porters Five Forces Analysis 13 Research Finding /Conclusion 14 Methodology and Data Source 14.1 Methodology/Research Approach

14.1.1 Research Programs/Design

14.1.2 Market Size Estimation

14.1.3 Market Breakdown and Data Triangulation14.2 Data Source

14.2.1 Secondary Sources

14.2.2 Primary Sources14.3 Disclaimer14.4 Author List

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COVID-19: Learn the virtues of patience from great cricketers – Gulf News

Sachin Tendulkar leaves a delivery outside the off stump during his playing days. Image Credit: AFP

Staying at home and maintaining hygiene are two important to dos for all to remain safe from the coronavirus disease. But to practice this, one needs tremendous patience and discipline. The game of cricket teaches these two traits, and most great players have these two qualities in abundance in them.

Staying on the batting crease and keep scoring runs do not come through sheer inborn talent alone. We have often heard about cricketers with great skills but repeatedly failing to post big scores.

During an interview with the legendary Sachin Tendulkar for the Friday Magazine, the Little Master told me: Discipline, focus, desire, passion, and fitness are a must if you want to achieve any form of longevity in any field. A disciplined and dedicated effort is what I followed.

At a time when coronavirus is threatening the longevity of everyones life, these qualities are ideal to be emulated. Even bowlers need these traits to be successful. Indias leg spinner Yuzvendra Chahal is a chess player turned cricketer and hed recently remarked that chess had taught him that even if he didnt get a wicket during a full day of a Test match, he could come back and get wickets the next day. Patience and the hope that the COVID-19 threat will end soon are vital; one cannot get disheartened during this phase.

Everyone has stressed on the importance of being mentally strong during this phase. Sunil Gavaskar, who spoke to Gulf News recently on the need to be mentally strong, is an embodiment of that. Had he been intimidated by the huge, well-built fast bowlers of West Indies, he would never have become the first man to reach the 10,000 Test runs in cricket.

Fear about the future and negativity are something that can grip anyone, especially when staying at home without interacting with people. The famous saying that an idle mind is a devils workshop can turn into reality during this phase. It is during such phases that one should visualise success and dream of achieving glory as soon as this crisis gets over.

This is the right time for everyone to try and read inspiring tales of sportsmen. Sport is about human endurance and the stories you may read are mostly about how sportsmen achieved success through determination.

Many young cricketers complain about not getting selected and on the lack of facilities that have hindered their progress. This is the time get rid of that habit - once and for all. Read an autobiography of a cricketer and there you will see how he managed to ride the toughest of odds to be successful.

This is not the time to complain as to how unlucky you are to be affected by this crisis. Remember, luck has always favoured the brave and the determined!

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COVID-19: Learn the virtues of patience from great cricketers - Gulf News

Adrenomyeloneuropathy Treatment Market: Strategic Analysis to Understand the Competitive Outlook of the Industry, 2025 – Science In Me

The Adrenomyeloneuropathy Treatment Market globally is a standout amongst the most emergent and astoundingly approved sectors. This worldwide market has been developing at a higher pace with the development of imaginative frameworks and a developing end-client tendency.

Adrenomyeloneuropathy Treatment market reports deliver insight and expert analysis into key consumer trends and behaviour in marketplace, in addition to an overview of the market data and key brands. Adrenomyeloneuropathy Treatment market reports provides all data with easily digestible information to guide every businessmans future innovation and move business forward.

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The worldwide Adrenomyeloneuropathy Treatment market is an enlarging field for top market players,

key players and government is expected to spur the adrenomyeloneuropathy treatment market.

The North America market for adrenomyeloneuropathy treatment is expected to retain its dominance, owing to increasing patient pool for rare disease, increasing government funding to accelerate the research and development for rare disease. According to Genetic and Rare Diseases Information Center, more than 25 million Americans are suffering from rare disease in United States.Europe is expected to account for the second largest share in the global adrenomyeloneuropathy treatment market owing to growing clinical trial funding programs for orphan drug development and high prevalence of adrenomyeloneuropathy and high treatment seeking rate. Asia Pacific is expected to show significant growth, owing to increasing diagnosis rate and improvement in healthcare infrastructure. China is expected to show significant growth in the adrenomyeloneuropathy treatment market, due to rising population improving R&D capability, increasing per capita heath spending. Latin America and Middle East & Africa is expected to show growth owing to lack of diagnosis and inadequate healthcare facilities and lack of skilled physicians for Adrenomyeloneuropathy Treatment market.

Examples of some of the key manufacturer present in the global adrenomyeloneuropathy treatment market are Ascend Biopharmaceuticals, Novadip Biosciences, Eureka Therapeutics, Human Longevity, Regeneus, Allogene Therapeutics, BioRestorative Therapies, Immatics Biotechnologies, NewLink Genetics, Cytori Therapeutics, Talaris Therapeutics among others.

The report covers exhaustive analysis on,

Regional analysis includes

Report Highlights:

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This Adrenomyeloneuropathy Treatment report begins with a basic overview of the market. The analysis highlights the opportunity and Adrenomyeloneuropathy Treatment industry trends that are impacted the market that is global. Players around various regions and analysis of each industry dimensions are covered under this report. The analysis also contains a crucial Adrenomyeloneuropathy Treatment insight regarding the things which are driving and affecting the earnings of the market. The Adrenomyeloneuropathy Treatment report comprises sections together side landscape which clarifies actions such as venture and acquisitions and mergers.

The Report offers SWOT examination and venture return investigation, and other aspects such as the principle locale, economic situations with benefit, generation, request, limit, supply, and market development rate and figure.

Quantifiable data:-

Geographically, this report studies the top producers and consumers, focuses on product capacity, production, value, consumption, market share and growth opportunity in these key regions, covering North America, Europe, China, Japan, Southeast Asia, India

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Research objectives and Reason to procure this report:-

Finally, the global Adrenomyeloneuropathy Treatment market provides a total research decision and also sector feasibility of investment in new projects will be assessed. Adrenomyeloneuropathy Treatment industry is a source of means and guidance for organizations and individuals interested in their market earnings.

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Adrenomyeloneuropathy Treatment Market: Strategic Analysis to Understand the Competitive Outlook of the Industry, 2025 - Science In Me

Only the toughest ginseng – Bangkok Post

Korean culture has globally disseminated through K-beauty as much as K-pop and K-drama have.

The history of Whoo harks back to the royal court of the Joseon Dynasty, in developing the Royal Privilege Cream, majestically priced at 70,500 baht.

Its launch in Bangkok was accompanied by an exhibition about the luxury brand, under LG Household & Healthcare.

Whoo refers to an empress whose age-old beauty secrets, along with records of the court's medical manuals, have been reinterpreted into modern-day cosmetics.

The logo recalls the haegeum, a traditional instrument that maintains harmony and balance of wind and string instruments. This reflects how its beauty products restore the balance of the skin.

Like how traditional Korean medicine prescribes ginseng as a panacea, the K-beauty brand swears by the medicinal herb as a powerful skincare ingredient.

Royal Privilege Cream powered by extracts of the wild ginseng family and flower.

The hefty price tag of the new face cream is due to Royal Empress Wild Ginseng -- a blend of extracts from different parts of a precious type of wild ginseng, Wang Whoo Sam, found in the northeastern part of the Baekdudaegan Mountain Range.

Crowned the Queen of Wild Ginseng, it grows as a family comprising mother and offspring with a strong vitality and longevity lineage. Only the toughest mother ginseng is able to deliver the baby ginseng, which further makes them a rare find in nature.

Common wild ginseng generally dies after 20-30 years, but this variety, as a group, lives twice as long, for 40-50 years. Moreover, it contains a high amount of active substances, for promoting healthy skin.

The Royal Privilege Cream also contains an extract from wild ginseng flowers, endowed with more phytocompounds than those found in the roots.

The inflorescence fully blooms from 8-10am, for only two to three days in a year, between mid May to June, when it is picked to capture the concentrated vital energy.

Likewise, the human body depends on a life force energy and a strong immune system that improves overall skin health.

The formulation of the Royal Privilege Cream is based on this principle, termed Dae-Bo-Won-Gi, which emphasises a fully-charged "original energy" in order to maintain a harmonious circulation of blood, vital energy and essence for healthy body and skin.

The Royal Privilege Pact comes with three applicators for different effects. The history of Whoo

From oriental medicine records, the researchers also learned of the cocoon's efficacy in softening the skin and how it was burned to release its medicinal properties.

This led to adding a silk protein, Sericin, to enrich the Royal Privilege Cream with nutrients while smoothening the texture of the formula.

The luxurious cream is housed in a handcrafted jar and box, inspired by a jade investiture book, appointment edict and gold seal engraved with the title, bestowed to a Korean empress in a royal coronation.

The regal cream was unveiled along with the Royal Privilege Pact, presented in a compact, evoking a jewellery box, with similar delicate metalwork and regal motif.

The pressed powder claims to contain traces of platinum, gold, sapphire, coral, pearl, ruby, diamond and amber, which justifies its price of over 27,500 baht.

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Only the toughest ginseng - Bangkok Post