Applied DNA Sciences Announces Industry Contracts for SigNature(R) DNA Marking of Electronics

STONY BROOK, NY--(Marketwire - Nov 29, 2012) - Applied DNA Sciences, Inc. ( OTCBB : APDN ), (Twitter: @APDN), a provider of DNA-based anti-counterfeiting technology and product authentication solutions, announced today that it has signed multiple contracts in support of the mandate by the Defense Logistics Agency for use of APDN's SigNature DNA marking and authentication technology.

These electronics companies have or will receive SigNature DNA and essential materials and services from APDN for DNA marking during or after manufacture.These steps will qualify them as SigNature DNA-compliant.

For manufacturers, a SigNature DNA Authenticity Mark as applied in production, certifies authenticity in an absolute, transparent and verifiable manner.For distributors and others, a SigNature DNA Provenance Mark establishes traceability to the point of the mark, assuring the entire supply chain that the part can be tracked to a supplier.

The contracts will enable electronics companies to fulfill the DLA mandate, announced on August 7 in a clause in Defense Logistics Acquisition Directive (DLAD) 52.211-9074, and expanded on November 7 with a provision atDLAD 52.211-9008. This mandate specifically requires SigNature DNA marking for procurements of items falling within Federal Supply Class 5962, Electronic Microcircuits. The requirement applies only to procurements made by DLA.

The developing list of participating defense contractors will enable the military electronics supply chain to move toward compliance with the anti-counterfeiting language in Section 818 of the National Defense Authorization Act for Fiscal Year 2012 (Section 818).A major deadline for Section 818, which imposes strict requirements for control of counterfeits, is due to be reached very soon. In a press announcement released on October 31, DLA pointed to the connection between the mandate and the coming implementation of NDAA Section 818:

The new requirement also facilitates the goals of Congress to protect DoD's supply chains and national cybersecurity, which Congress outlined in the 2012 National Defense Authorization Act. This requires DoD, as well as industry, to develop counterfeit item detection and prevention measures for electronic items.

In the same press announcement, DLA stressed the "broad implications" of its DNA marking mandate, stretching beyond electronics, saying:

DLA is initially targeting microelectronics, but the technology is used with other commodities commercially and has broad implications for other DLA products and equipment at risk for counterfeiting.

APDN suggested that electronics companies check with suppliers to find whether they have joined the list of companies which are SigNature DNA-compliant.

Janice Meraglia, Vice President, Military and Government Programs for Applied DNA Sciences, said, "DLA, in its efforts to provide support to our war fighters, has worked for years to develop new technology and processes to mitigate counterfeit risk.We are pleased to see these efforts materialized in the electronics industry, something which will benefit industry and national security."

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Applied DNA Sciences Announces Industry Contracts for SigNature(R) DNA Marking of Electronics

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DNA Directly Photographed for First Time

Fifty-nine years after James Watson and Francis Crick deduced the double-helix structure of DNA, a scientist has captured the first direct photograph of the twisted ladder that props up life.

Enzo Di Fabrizio, a physics professor at the Magna Graecia University in Catanzaro, Italy, snapped the picture using an electron microscope.

Previously, scientists had only seen DNA's structure indirectly. The double-corkscrew form was first discovered using a technique called X-ray crystallography, in which a material's shape is reconstructed based on how X-rays bounce after they collide with it.

But Di Fabrizio and his colleagues developed a plan to bring DNA out of hiding. They built a nanoscopic landscape of extremely water-repellant silicon pillars. When they added a solution that contained strands of DNA into this scene, the water quickly evaporated and left behind cords of bare DNA that stretched like tightropes between the tiny mesas.

They then shone beams of electrons through holes in the silicon bed, and captured high-resolution images of the illuminated molecules.

Di Fabrizio's images actually show a thread of several interwoven DNA molecules, as opposed to just two coupled strands. This is because the energy of the electrons used would be enough to destroy an isolated double helix, or a single strand from a double helix.

But with the use of more sensitive equipment and lower energy electrons, Di Fabrizio thinks that snapshots of individual double helices will soon be possible, reports New Scientist.

Molecules of DNA, or deoxyribonucleic acid, store the genetic instructions that govern all living organisms' growth and function.

Di Fabrizio's innovation will allow scientists to vividly observe interactions between DNA and some of life's other essential ingredients, such as RNA (ribonucleic acid). The results of Di Fabrizio's work were published in the journal NanoLetters.

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DNA 'LEGOs' Build a Mini Space Shuttle

A tiny space shuttle made out of DNA "LEGO bricks" shows how scientists could someday build new technologies on the smallest scales.

Single DNA strands became "LEGO bricks" that could assemble together by themselves into 102 individual 3D shapes. Harvard researchers manipulated the DNA coding of the bricks so that they could form solid shapes such as the tiny shuttle, honeycomb structures, and even "written" features on a solid base such as numbers and letters of the English alphabet.

"Once we know how to compile the correct code of complex shapes and add it to the synthetic DNA strands, everything else is simple and natural," said Yonggang Ke, a chemist at Harvard University. "Those DNA strands are like smart LEGO bricks that know exactly where to go by themselves."

DNA bricks offer a powerful new tool for building structures in the tiniest detail, according to Ke and his colleagues in their study detailed in the Nov. 29 online edition of the journal Science. The work could lead to tiny medical devices for delivering drugs inside the human body or next-generation computer circuits.

But the DNA nanotechnology breakthrough also touches upon one of science's greatest mysteries how life on Earth assembled itself from a jumble of molecules in the primordial ooze. A DNA strand's width is about 1 nanometer (1 billionth of a meter) far smaller than a human hair's width of 60,000 nanometers.

Replicating life's miracle

The idea of DNA bricks that can assemble into shapes on their own seems fantastical for humans used to building things step-by-step. But it's just a hint of what nature does all the time through self-assembly, Ke said.

"All life forms on earth are self-assembled, in an environment of an enormous amount of small molecules and macromolecules, such as DNA, RNA and proteins much, much messier than our small DNA "soup" in a test tube," Ke told TechNewsDaily.

The Harvard lab of Peng Yin, senior author on the new study, had used DNA to build 2D shapes. The 3D breakthrough relied upon the bricks each consisting of a single DNA strand with 32 nucleotides DNA's building block molecules that can bind to as many as four neighboring bricks.

Two bricks connect to one another at a 90-degree angle to form a 3D shape, similar to connecting a pair of two-stud LEGO bricks. Researchers designed the 3D shapes they wanted by manipulating the coded "recipe" of how DNA's base pair molecules bind to one another. [New DNA Computer Stores 1 Bit of Data]

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DNA 'LEGOs' Build a Mini Space Shuttle

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Chemists tackle Green Energy question – Video


Chemists tackle Green Energy question
An iridium-based catalyst under research at UCD may be key to splitting water efficiently to release dioxygen and dihydrogen - considered to be the fuel of the future. Here Professor Martin Albrecht talks about the work of his lab in the UCD School of Chemistry and Chemical Biology.From:UCDAlumni1Views:0 0ratingsTime:02:25More inEducation

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Transfer liquid from one tube to several wells or microtubes – Video


Transfer liquid from one tube to several wells or microtubes
Andrew Assistant allows you to design protocol for biology very easily. Perfect to make aliquots, this software is well designed by biologist and for biologist. Download it for free on our website http://www.andrewalliance.comFrom:Isabelle SemacViews:0 0ratingsTime:01:00More inScience Technology

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Connexon – Wiki Article – Video


Connexon - Wiki Article
In biology, a connexon, or hemichannel, is an assembly of six proteins called connexins that can be a part of a gap junction channel between the cytoplasm of two adjacent cells. The connexon is actu... Connexon - Wiki Article - wikiplays.org Original @ http All Information Derived from Wikipedia using Creative Commons License: en.wikipedia.org Author: LadyofHats Image URL: en.wikipedia.org ( This work is in the Public Domain. )From:WikiPlaysViews:0 0ratingsTime:00:57More inEducation

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NYGC Welcomes Robert Darnell as President


NYGC Welcomes Robert Darnell as President Scientific Director
Robert B. Darnell, MD, Ph.D., a leading expert in the emerging area of RNA genomics, was named President and Scientific Director of the New York Genome Center on November 28, 2012. While he #39;s new to the role of President and Scientific Director, Darnell is no stranger to NYGC. He was part of the Center #39;s founding board and executive committee, and he #39;s the Heilbrunn Professor of Cancer Biology at The Rockefeller University, which is also home to NYGC #39;s Pilot Lab. He #39;ll retain that position and continue to be an Investigator of the Howard Hughes Medical Institute.From:NewYork GenomeCenterViews:3 0ratingsTime:01:45More inScience Technology

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NYGC Welcomes Robert Darnell as President

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Methanogen – Wiki Article – Video


Methanogen - Wiki Article
Methanogens are microorganisms that produce methane as a metabolic byproduct in anoxic conditions. They are classified as archaea, a biology domain quite distinct from bacteria. They are common in we... Methanogen - Wiki Article - wikiplays.org Original @ http All Information Derived from Wikipedia using Creative Commons License: en.wikipedia.org Author: ms:User:PM Poon Image URL: en.wikipedia.org ( Creative Commons ASA 3.0 )From:WikiPlaysViews:0 0ratingsTime:10:13More inEducation

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Integrated Fly Management Around Confined Livestock, Part One: Biology – Video


Integrated Fly Management Around Confined Livestock, Part One: Biology
This beginning portion of the presentation describes the problems caused by pest flies around confined livestock such as cattle. Integrated Pest Management (IPM) is introduced as an effective way to control pest flies in this situation. The first step in IPM, Biology and Identification of the pest, is described.From:NYSIPMViews:4 1ratingsTime:10:25More inScience Technology

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Trent Luminary – Dr. Maggie Xenopoulos – Video


Trent Luminary - Dr. Maggie Xenopoulos
The acclaimed ecologist, Dr. David Schindler, has likened the eutrophication of freshwater lakes to the Dust Bowl of the nineteen thirties, because both resulted from bad land use practices. As inaugural holder of the David Schindler Professorship in Aquatic Science, Dr. Paul Frost also worries about the quality of our water and how to maintain healthy levels of algae in our lakes. Dr. Frost, an assistant professor in the Department of Biology, is working to improve and enhance water quality in the Kawartha Lakes and other aquatic ecosystems in southern Ontario. Dr. Frost #39;s concern for our fresh waters is shared by his partner and colleague, Dr. Maggie Xenopoulos. A recognized expert in global change biology, Dr. Xenopoulos is dismayed by the impact that human activities are having on the natural environment. "What we are doing to the planet is terrible," says Dr. Xenopoulos, whose research examines how urban and agricultural land use affects the function of water bodies. "We are lucky in Ontario to have an abundance of fresh water, unlike anywhere in the world." As a lead author in the United Nations Millennium Ecosystem Assessment, Dr. Xenopoulos helped developed future scenarios for freshwater biodiversity. The study revealed that approximately 60 per cent of ecosystem services are at risk. For her work she was named a co-recipient of the Zayed International Prize for the Environment. Despite their concerns, both professors see Trent University as uniquely positioned ...From:trentUniversityViews:3 0ratingsTime:04:02More inEducation

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