Biochemistry is the branch of science that explores the chemical processes within and related to living organisms. It is a laboratory based science that brings together biology and chemistry. By using chemical knowledge and techniques, biochemists can understand and solve biological problems.

Biochemistry focuses on processes happening at a molecular level. It focuses on whats happening inside our cells, studying components like proteins, lipids and organelles. It also looks at how cells communicate with each other, for example during growth or fighting illness. Biochemists need to understand how the structure of a molecule relates to its function, allowing them to predict how molecules will interact.

Biochemistry covers a range of scientific disciplines, including genetics, microbiology, forensics, plant science and medicine. Because of its breadth, biochemistry is very important and advances in this field of science over the past 100 years have been staggering. Its a very exciting time to be part of this fascinating area of study.

To find out more about careers in biochemistry read our bookletsBiochemistry: the careers guideandNext Steps.

The life science community is a fast-paced, interactive network with global career opportunities at all levels. The Government recognizes the potential that developments in biochemistry and the life sciences have for contributing to national prosperity and for improving the quality of life of the population. Funding for research in these areas has been increasing dramatically in most countries, and the biotechnology industry is expanding rapidly.

The Biochemical Societyaims to inspire and engage people in the molecular biosciences. We offer study and careers advice toschool students,higher education studentsandteachersas well as carrying outpublic engagementevents.

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What is biochemistry? Biochemical Society

On April 15, Dr Aqsa Shaikh, a self-proclaimed queer activist, teacher of community medicine at Jamia Hamdard and nodal officer of a COVID vaccination centre, sparked a controversy by saying that the medical curriculum in India teaches too much Anatomy and Biochemistry. Dr Aqsa also claimed heterosexual doctors should not teach about queer lives. Furthermore, she said, Instagram teaches more about sexual and gender Minorities than textbooks. Her statement attracted strong criticism on social media.

In a series of tweets, Dr Aqsa mentioned the points she had raised during a panel discussion on making Medical Curriculum queer affirmative at AIIMS. She said the fraternity should stop medicalising queer identities. Furthermore, she claimed that the Indian medicine curriculum is teaching too much of Anatomy and Biochemistry. According to her, 5.5 years were not enough to learn about health.

Dr Aqsa demanded that Medical Science should be turned into a Bachelor of Health and the students should be taught subjects of humanities with medicines. She said it is time to reverse Millers Pyramid, Empathy should be the base, not Cognitive domain. She claimed the CBME (Competency Based Medical Education) curriculum is flawed and suggested that doctors should be political.

Interestingly, she added that Heterosexual people should not teach about queer lives and demanded more marginalised communities should be brought in as teaching staff. According to Dr Aqsa, the current Transgender Act has many anti-queer laws, and it needs amendments. The education about queer should begin at the primary level and not at medical school. One of the most controversial statements she made in her tweets was that Instagram taught more about sexual and gender minorities compared to the textbooks.

Her statement has attracted sharp criticism, especially from the Medical community on Twitter. Dr Lira questioned why such discussions were even allowed by AIIMS. She said, From where is this irrational thinking seeping into #medical system? Why is AIIMS even allowing this? Medicine is pure Science unadulterated by Identity politics, religion and superstitions. One can practice medicine with basic human decency without needless affirmation.

Dr Pranay said, First, it made me laugh. Then I realised she was serious. Not just a tweet, but this was rather a panel discussion at AIIMS. Im worried now. Ridiculous is too small a term for this.

Dr Apporva Verma said, Too much anatomy? Seriously? While I get 1st point, Id like to know this persons qualification to have uttered such statement as the 2nd point.

Speaking to OpIndia, Dr Haryax Pathak said, While the issue in the hand of LGBTQ rights and awareness is a genuine one, there has to be a systematic approach towards it. It starts by educating people. The biology behind it. The history behind it. That means more Anatomy, more Biochemistry not less. Training empathy is required, but it is a slow process. Im against the claim that doctors must be political. I can have political preferences as an individual but they dont reflect in my professional life. Doctors dont differentiate or discriminate on a political basis.

He further added, Claims that Instagram teaches more than medical school are way harmful. There has to be a professional approach to medical education. Ironical that slurs of WhatsApp University are passed around while promoting Instagram education. He agreed there was a need for some legal amendments as transgenders are humans too, and they have rights equal to everybody else.

Originally posted here:
Too much Anatomy and Biochemistry, Instagram better than textbooks on sexual and gender minorities Jamia Hamdards Dr Aqsa Shaikh wants to change...

Advanced studies of human genetics are a big wave in the medical sciences. Collaborative teams of clinical geneticists and bioinformaticians are surfing this wave, rapidly discovering genomic variations associated with specific human disorders. This trend is providing scientific bases for personalized medicines but also new, important questions linked to the basic biochemistry field.

Ceramidetransport protein, or CERT, moves the waxy lipids known as ceramides in cells for the synthesis of sphingomyelin, a membrane lipid that is ubiquitous in mammalian cells. In 2007, researchers found that CERT is functionally repressed by multiple phosphorylations of a serine-repeat motif, or SRM, in CERT. At the time, scientists regarded this finding as pure biochemistry of a protein.

However, a decade later, large-scale human genetic studies on intellectual disabilities and mental development disorders, or ID/MD, showed that missense mutations in or near the CERT SRM-encoding regions are associated with a type of autosomal dominant hereditary ID/MD. The dominant inheritance was in line with a prediction from the previous biochemical study that loss of hyperphosphorylation of the SRM renders CERT abnormally active.

Our recent collaborative study confirmed this prediction by demonstrating that substitution of a serine residue in the SRM with other residues similar to variants found in ID/MD patients results in dysregulation of CERT in cultured cells. Nonetheless, several ID/MD-associated missense mutations that occurred in the CERT gene CERT1 also are mapped outside the SRM. This riddle was answered by another recent study showing that a non-SRM variant also compromises the SRM hyperphosphorylation, thereby abnormally activating CERT.

Moreover, cell biological analysis showed that abnormally activated CERT mutants exhibit an aberrant punctate distribution in cells, suggesting that the subcellular distribution pattern is applicable as a diagnostic tool to assess whether a CERT1 variant is an abnormally activated type that may cause ID/MD, although the precise identity of the puncta structure remains undetermined.

Kentaro Hanada

Advanced human genetics studies have shown that missense mutations in the CERT1 gene encoding the ceramide transport protein CERT are associated with certain intellectual disabilities and mental development disorders. Recent studies in the Hanada lab showed that ID/MD-associated CERT variants are defective in the serine-repeat motif phosphorylation-dependent repression. In this diagram, for simplicity, CERT is illustrated as a monomer, although it forms oligomers in cells.

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Dysregulation of a lipid transfer protein linked to brain disorders - ASBMB Today

April 8, 2021

If science is your favorite school subject, consider a biochemistry role. This lab-based science studies why certain substances cause reactions in the cells of various living beings. There are many specialties you can pursue within this degree that can ready you for careers like biochemists, chemical engineers or professors. In this article, we review what biochemistry is, tips for becoming a biochemist and the different roles you can pursue with a biochemistry degree.

Biochemistry is the combination of chemistry, physics and biology. Biochemistry professionals study how these different elements of science affect various living beings and organisms. Many students looking to explore the chemical processes that take place within a living system typically major in biochemistry. Most of the careers you can earn in this degree vary according to your preferred responsibilities and work environment. This degree allows you to specialize in a wide variety of fields, including chemistry, biology and research.

To become a biochemist or to work in the biochemistry field, you must have impressive scientific skills, knowledge and capabilities. You can earn these qualifications by taking the proper courses and gaining relevant experience in your field. Follow these tips to become a successful biochemist:

Earn a high school diploma: You should first graduate high school with your diploma or a GED. Try to take courses like physics, chemistry, mathematics and biology to familiarize yourself with the basic scientific concepts you may later go in-depth on in your bachelor's program.

Get a bachelor's degree: Most employers require biochemistry candidates to earn at least a bachelor's degree in biochemistry, biology, chemistry or another related field.

Select elective courses: Many programs offer elective courses depending on the area of the biochemistry field that you'd like to pursue. You can take courses that help you advance your education further into the medical, biotechnology or veterinary master's degree programs.

Participate in lab work: A majority of biochemistry careers take place in a laboratory. You may complete lab work during your courses to familiarize yourself with the tools and overall lab atmosphere. You can also pursue an internship in a lab to gain hands-on lab training and experience.

There are a wide variety of fields you can pursue, such as forensic science, chemistry and biology, after you earn a biochemistry degree. Common jobs people with biochemistry degrees typically pursue include:

National average salary: $51,544 per year

Primary duties: A forensic science technician assists forensic scientists in criminal investigations to perform tests and report their results. Common job responsibilities include collaborating with law enforcement at crime sciences to collect DNA, running DNA profiling and chemical analysis tests, testifying as an expert witness in court and handling hazardous and contaminated pieces of physical evidence safely and responsibly.

Related: Learn About Being a Forensic Science Technician

National average salary: $63,734 per year

Primary duties: Forensic scientists process various pieces of evidence to help law enforcement prosecute suspects in criminal cases. Other responsibilities include interpreting blood spatter patterns at crime scenes, tracing drugs and other illegal substances in tissues and bodily fluids, managing and preserving crime scenes until the necessary personnel arrives and conducting post-mortem investigations on crime scene victims.

National average salary: $63,908 per year

Primary duties: A chemical engineer uses their advanced knowledge of mathematics and different areas of science to enhance the processes used in chemical experiments. They also work to find solutions to problems that scientists in the chemical industry may regularly undergo. Other key job duties include building, proposing and implementing plans to reach chemical companies' goals, increasing the quality and efficiency levels of chemical processes and compiling and analyzing data gained from on-site visits.

Related: Learn About Being a Chemical Engineer

National average salary: $65,066 per year

Primary duties: A biochemistry professor works for a university, college or other academic institution teaching students about different elements of biochemistry. Their main duties include providing lectures, administering tests, quizzes and assignments, conducting office hours to address students' questions about the lectures, overseeing lab experiments students conduct and developing syllabi that reflects the program's required curriculum.

National average salary: $79,272 per year

Primary duties: A biochemist conducts studies and experiments on the composition and functions of different life forms to determine how various chemical processes affect them. Other key job responsibilities include designing and executing scientific experiments, analyzing and recording large data sets and results, making recommendations on chemical processes based on their findings and refining chemical compounds for medical professionals or the public to use.

National average salary: $80,831 per year

Primary duties: A biologist studies plant life and other organisms to make discoveries about their behaviors, compositions and habitats. They also conduct research on these living beings to determine how other beings or organisms affect their environments. Other job duties include identifying, studying and classifying animals, plants and ecosystems, taking samples and measurements of organisms, learning more about organisms' diets and behaviors and maintaining detailed and accurate records related to their scientific research.

National average salary: $94,755 per year

Primary duties: A medical scientist conducts research on human illnesses and diseases to uncover ways to improve the health of humans. Other job responsibilities include conducting studies to investigate human diseases and potential treatment methods, analyzing medical data and samples to determine causes and dangers of certain chronic diseases or pathogens, building and testing various medical devices and writing research grant proposals for funding applications from private funding and government sources.

National average salary: $111,143 per year

Primary duties: A research scientist conducts experiments on different scientific concepts to prove or disprove certain scientific theories or insights. Other job responsibilities include proposing innovative scientific research ideas, spearheading data collection processes and efforts and publishing important findings in scholarly and academic journals.

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8 Jobs To Pursue With a Biochemistry Degree | Indeed.com

Have you ever observed how the chemical reactions or the processes occur within the human body? How do metabolic activities take place? Yes, you will get to know all these life processes through Biochemistry.

The branch of science dealing with the study of all the life processes such as control and coordination within a living organism is called Biochemistry.

This term was introduced to us by Carl Neuberg, the father of biochemistry in the year 1930. This field combines biology as well as chemistry to study the chemical structure of a living organism. The biochemists get into the investigation of the chemical reactions and combinations which are involved in various processes like reproduction, heredity, metabolism, and growth, thus performing research in different kind of laboratories.

Introduction to Biochemistry includes wide areas of molecular biology as well as cell biology. It is relevant to molecules that make up the structure of organs and cells which is the molecular anatomy. It describes carbon compound and the reactions they undergo in living organisms. It also describes molecular physiology, which is the functions of molecules in carrying out the requirements of the cells and organs.

It mainly deals with the study of the structure and functions of the biomolecules such as the carbohydrates, proteins, acids, lipids. Hence, it is also called to as Molecular biology.

The primary branches of biochemistry are listed in this subsection.

It is also referred to as the roots of Biochemistry. It deals with the study of functions of the living systems. This field of biology explains about all the interactions between the DNA, proteins, RNA and their synthesis.

Cell biology

Cell Biology deals with the structure and functions of cells in living organisms. It is also called as Cytology. Cell biology primarily focuses on the study of cells of the eukaryotic organisms, and their signalling pathways, rather focussing on to prokaryotes- the topics that will be covered under microbiology.

Metabolism

Metabolism is one of the most important processes taking place in all the living things. It is nothing but the transformations or the series of activities that happens that when food is converted into energy in a human body. One of the examples of metabolism is the process of digestion.

Genetics

Genetics is a branch of biochemistry that deals with the study of genes, their variations and the heredity characteristics in living organisms.

The other branches include Animal and Plant Biochemistry, Biotechnology, Molecular Chemistry, Genetic engineering, Endocrinology, Pharmaceuticals, Neurochemistry, Nutrition, Environmental, Photosynthesis, Toxicology, etc.

Biochemistry is essential to understand the following concepts.

To learn more about biochemistry and other important branches of chemistry, such as physical chemistry, register with BYJUS now!

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What is Biochemistry? - Definition, History, Examples, Importance ...

image:The ARDD Meeting 2022 will be hosted on August 29 - September 2, 2022 view more

Credit: Insilico Medicine Hong Kong Limited

April 11, 2022 - Matthias Mann, Ph.D., will present the latest research on the topic Single cell and Deep Visual Proteomics and its applications in precision medicine at the worlds largest annual Aging Research and Drug Discovery conference (9th ARDD). Dr.Matthias Mann is the Director, Department of Proteomics and Signal Transduction at the Max Planck Institute of Biochemistry.

By merging the power of microscopy, AI and our ultra-sensitive MS-based proteomics workflow, we have developed a method that is very powerful in dissecting tissue heterogeneity at single-cell resolution - something that had not been possible at the protein level before. We expect DVP to be applicable to personalized medicine. said Matthias Mann, Ph.D., Director, Department of Proteomics and Signal Transduction at the Max Planck Institute of Biochemistry.

Matthias Mann is the Director at the Max Planck Institute for Biochemistry near Munich, and manages the proteomics program at the Novo Nordisk Foundation Center for Protein Research at the Medical School in Copenhagen. He is a pioneer and leader in mass spectrometry-based proteomics, where he has helped develop many of the foundational technologies such as electrospray, peptide sequence tags, quantitative proteomics and many more. The core interests of his groups are signal transduction, MS technological development and bioinformatics, with a main focus on clinical proteomics for better diagnosis, prognosis and biological understanding of diseases.

The conference proceedings of the ARDD are commonly published in peer-reviewed journals with the talks openly available at http://www.agingpharma.org. Please review the conference proceedings for 2019, 2020 and 2021https://www.aging-us.com/article/203859/text .

Aging is emerging as a druggable condition with multiple pharmaceuticals able to alter the pace of aging in model organisms. The ARDD brings together all levels of the field to discuss the most pressing obstacles in our attempt to find efficacious interventions and molecules to target aging. The 2022 conference is the best yet with top level speakers from around the globe. Im extremely excited to be able to meet them in person at the University of Copenhagen in late summer. said Morten Scheibye-Knudsen, MD, Ph.D., University of Copenhagen.

Aging research is growing faster than ever on both academia and industry fronts. The ARDD meeting unites experts from different fields and backgrounds, sharing with us their latest groundbreaking research and developments. Our last ARDD meeting took place both offline and online, and it was a great success. I am particularly excited that being a part of the ARDD2022 meeting will provide an amazing opportunity for young scientists presenting their own work as well as meeting the experts in the field. said Daniela Bakula, Ph.D., University of Copenhagen.

Many credible biopharmaceutical companies are now prioritized aging research for early-stage discovery or therapeutic pipeline development. It is only logical to prioritize therapeutic targets that are important in both aging and age-associated diseases. The patient benefits either way. The best place to learn about these targets is ARDD, which we organize for nine years in a row. This conference is now the largest in the field and is not to be missed, said Alex Zhavoronkov, Ph.D., founder and CEO of Insilico Medicine and Deep Longevity.

Building on the success of the ARDD conferences, the organizers developed the Longevity Medicine course series with some of the courses offered free of charge at Longevity.Degree covered in the recent Lanced Healthy Longevity paper titled Longevity medicine: upskilling the physicians of tomorrow.

About Aging Research for Drug Discovery Conference

At ARDD, leaders in the aging, longevity, and drug discovery field will describe the latest progress in the molecular, cellular and organismal basis of aging and the search for interventions. Furthermore, the meeting will include opinion leaders in AI to discuss the latest advances of this technology in the biopharmaceutical sector and how this can be applied to interventions. Notably, this year we are expanding with a workshop specifically for physicians where the leading-edge knowledge of clinical interventions for healthy longevity will be described. ARRD intends to bridge clinical, academic and commercial research and foster collaborations that will result in practical solutions to one of humanity's most challenging problems: aging. Our quest? To extend the healthy lifespan of everyone on the planet.

About Scheibye-Knudsen Lab

In the Scheibye-Knudsen lab we use in silico, in vitro and in vivo models to understand the cellular and organismal consequences of DNA damage with the aim of developing interventions. We have discovered that DNA damage leads to changes in certain metabolites and that replenishment of these molecules may alter the rate of aging in model organisms. These findings suggest that normal aging and age-associated diseases may be malleable to similar interventions. The hope is to develop interventions that will allow everyone to live healthier, happier and more productive lives.

About Deep Longevity

Deep Longevity has been acquired by Edurance RP (SEHK:0575.HK), a publicly-traded company. Deep Longevity is developing explainable artificial intelligence systems to track the rate of aging at the molecular, cellular, tissue, organ, system, physiological, and psychological levels. It is also developing systems for the emerging field of longevity medicine enabling physicians to make better decisions on the interventions that may slow down, or reverse the aging processes. Deep Longevity developed Longevity as a Service (LaaS) solution to integrate multiple deep biomarkers of aging dubbed "deep aging clocks" to provide a universal multifactorial measure of human biological age. Originally incubated by Insilico Medicine, Deep Longevity started its independent journey in 2020 after securing a round of funding from the most credible venture capitalists specializing in biotechnology, longevity, and artificial intelligence. ETP Ventures, Human Longevity and Performance Impact Venture Fund, BOLD Capital Partners, Longevity Vision Fund, LongeVC, co-founder of Oculus, Michael Antonov, and other expert AI and biotechnology investors supported the company. Deep Longevity established a research partnership with one of the most prominent longevity organizations, Human Longevity, Inc. to provide a range of aging clocks to the network of advanced physicians and researchers. https://longevity.ai/

About Endurance RP (SEHK:0575.HK)

Endurance RP is a diversified investment group based in Hong Kong currently holding various corporate and strategic investments focusing on the healthcare, wellness and life sciences sectors. The Group has a strong track record of investments and has returned approximately US$298 million to shareholders in the 21 years of financial reporting since its initial public offering. https://www.endurancerp.com/

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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Matthias Mann to present at the 9th Aging Research & Drug Discovery Meeting 2022 - EurekAlert

The American Association for the Advancement of Science (AAAS) is the worlds largest multidisciplinary society for the sciences and a leading publisher of research. Each year, the AAAS Council elects Fellows for their research and its applications significant to science and society. In 2021, nine UChicago professors were named AAAS Fellows.

Phoebe A. Rice

Biochemistry and molecular biophysics professor Phoebe A. Rices research focuses on the fundamentals of biochemical systems, specifically how proteins control DNA and mobile genetic elements.

I think weve made a lot of contributions to understanding DNA rearrangement reactions from a very fundamental biochemistry point of viewhow they are orchestrated and controlled, Rice said. For the DNA rearrangement enzymes Im working on now, one of my hopes is that people can use the tools were developing to get microbes to make biofuels, which will be very useful to the planet.

Rice prizes the laboratory work involved in her research. I find [the laboratory work] amazingit shows the intricacies of how Mother Nature pulls things off, Rice said. To some degree, I view it almost as art. Its showing people how beautiful nature is even at the tiny level.

In the study of protein structures, there has been a recent revolution in artificial intelligence methods. Within the last year, artificial intelligence methods have gotten very good at looking at enormous databases of protein structures and sequences and then taking a new sequence and guessing the structure, Rice said. We can make predictions that give you testable hypotheseswithout even having to lift a pipette.

Amanda Woodward

Amanda Woodward, Dean of the Division of the Social Sciences and the William S. Gray Distinguished Service Professor of Psychology, is a founding member of UChicagos Center for Early Childhood Research. As a developmental psychologist, Woodward studies how infants make sense of other people's actions and interactions. Human beings are really intensely social species, Woodward said. So understanding who we are as thinkers, reasoners, and learners sort of depends on understanding how we react to the social context.

Woodwards most highly cited paper was published in 1998; it details her discovery that infants are able to recognize the difference between object and human movements and see the latter as goal-directed. It established a whole program of research in my lab and also inspired a lot of research around the world, Woodward said.

This was followed by another discovery that babies reasoning about other peoples behavior is directly connected with their motor development. Woodwards lab found that the babys own ability to use tools predicted how they were going to reason about other peoples actions and abilities.

During my lifetime, there have been really important discoveries in this field that have shaped what we know about the human mind and its development, so that makes it exciting to be in science and part of that discovery process. Thats what motivates my work, Woodward said.

Yoav Gilad

Professor of Medicine Yoav Gilad focuses on functional genomics, analyzing phenotypes at the molecular level to better understand clinically relevant differences between people.

One of the current projects that his lab is working on involves developing a new cell culture model using an in vitro system, which will allow them to characterize environmental interactions with human genomes during early development. If we're correct about the potential of this new system, then I believe that it can truly change the amount of insight we can have into patients' risk and response to medication, Gilad said. It can even help with developing new medicine by testing it much more rapidly in the lab before going through testing phases.

Gilads interest in this area was largely inspired by his study of olfaction while in pursuit of his doctorate degree. Through my work on olfaction, I became very interested not just in the different ways that we can smell things, but just in general the relationship between genes, environment, and our phenotypic differences, Gilad said. Over the last decade or so, I became interested in how we can use these tools to actually make an impact in the health system and in the clinic.

One of the most significant discoveries made by Gilad and his lab has been in the area of gene regulation and variation, where they produced one of the first maps to track rotary mechanisms. Another significant discovery comes from Gilads work in comparative genomics; Gilad and his team established the first panel of chimpanzee stem cells, which they now freely share with other scientists. I'm very proud that there are dozens of papers that are not from our lab, but use our cells, the resources that we developed, to really enhance that field, Gilad said.

Michael Coates

Michael Coates is a Professor of Organismal Biology and Anatomy whose research focuses on early vertebrate diversity and evolution. He is most interested in discovering morphology, the origin and form that underlies vertebrate body parts, using fossils to look at the early radiation of modern vertebrate groups. Coates works primarily with fish, and collaborates closely with fish labs that look at the developmental biology side of fish.

One of Coatess biggest accomplishments was discovering the earliest limbs with digits in his postdoctoral work. Coates and his colleagues found that the number of digits varied, as opposed to the widely accepted standard number of five digits. Although Coates has made several discoveries and contributions to the field of morphology, he continues to be fascinated by fundamental questions regarding the genetic path to morphology and what this means in the context of how genes and development have changed throughout time, as well as how this process has been shaped by the history of the planet. It's clear that there are big, big gaps in the early record of vertebrate life. I'd love to see those filled, and we have gotten better tools for this imaging and making sense of it.

Jeanne C. Marsh

Jeanne C. Marsh is the George Herbert Jones Distinguished Service Professor in the Crown Family School of Social Work, Policy, and Practice and the Director of the Center for Health Administration Studies. Marshs work focuses on health services research that looks at the integration of health and social services.

Currently, Marsh is focusing on the health disparities area; her team is studying the impact of substance abuse treatment on client functioning, specifically in women and children. One of the studies that she is leading is a study in Los Angeles County on the opioid epidemic. They are looking closely at not only gender disparities, but also race and ethnic disparities and how they can help improve access to treatment for these marginalized populations.

I think one hallmark of my work is a sense that we really need to do whatever data collection is necessary to hear directly from the people who are in the real world experiencing these issues, Marsh said. It isn't good enough just to pick up a big data set and run some analysis, it's really important to get the perspective of the people who are engaged in the process, who may be receiving the services.

One of the most significant parts of Marshs research has been becoming increasingly aware of health disparities which stem from broader social inequities. Findings from my research show that targeting health and social services to specific client needs significantly improves their health and social functioning, Marsh said. I bring a social work perspective to this research indicating that asking clients what health and social services they need and then providing them improves client outcome and satisfaction when compared to alternative approaches.

Marsh is also taking part in a new project that involves faculty members from both the Department of Medicine and the Crown Family School. They are primarily interested in health care for the disadvantaged, specifically in Medicare and Medicaid data. That's really the exciting part about science, when you can work together with really smart people in the process of discovery, addressing whatever your curiosity might be.

Maria-Luisa Alegre

Professor of Medicine Maria-Luisa Alegres research focuses on the molecular mechanisms involved in organ transplants. One area is centered around tolerance, while the other is centered on studying the impact of different environmental factors, specifically microbiota.

Currently, Alegre and her team are working with mice to explore how the immune response is altered by the gut microbiota. Their goal is to answer the question of how the microbiota that colonizes the transplanted organ itself influences the immune response to that organ and the commensals that colonize the organ. They are also working on figuring out what components of the immune system are being awakened to reject the organ when challenges that can threaten tolerance arise, such as severe infections.

Her goal for her research ultimately goes back to making an impact in the clinic. We would like to get to a point where we understand the mechanisms that underlie transplantation tolerance well enough that we could translate that into the clinic and be able to follow and monitor the cells of patients who are transplanted, Alegre said.

Edward Blucher

Edward Blucher is a Professor of Physics whose research focuses on particle physics. His studies center around exploring the imbalance that built up in the first millionth of a second or so during the Big Bang. Almost everything I have been studying is broadly connected by one big physics question, which is trying to better understand what happened early in the universe between matter and antimatter.

One of Bluchers most significant discoveries was on symmetry violation. We were looking for a very particular kind of violation in the way that a kaon decayed. In 1999, we finally found that this symmetry violation existed. It was very exciting because this was the kind of thing that would be needed for the universe to evolve the way it had existed in nature, Blucher said.

Blucher then developed an interest in neutrinos and their role in how the universe evolved to be imbalanced in matter and antimatter, and this is when DUNE was started. DUNE is an experiment that involved about 1400 physicists from 35 countries. It focused on looking for a violation of this matter and antimatter asymmetry in neutrinos by sending a beam of particles of neutrinos from Fermilab all the way to South Dakota.

Blucher is now working on an experiment that is also deep underground in a mine in northern Ontario that is looking at a rare type of nuclear decay. I think that asking about asymmetry is just a fascinating question, because it's something that we wouldn't be here without, Blucher said. It's a question that's really connected with how matter exists at all.

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2021 AAAS Fellows Share Their Experience in Scientific Research - The Chicago Maroon

This article was originally published here

PLoS One. 2022 Apr 6;17(4):e0266419. doi: 10.1371/journal.pone.0266419. eCollection 2022.

ABSTRACT

The pandemic caused by the SARS-CoV-2 virus (COVID-19) is still a major health issue. The COVID-19 pandemic has forced the university teaching to consider in high priority the switch from in-presence teaching to remote teaching, including laboratory teaching. While excellent virtual-laboratory teaching has been proposed and turned out to be very useful, the need of a real-laboratory in-presence teaching is still a major need. This study was aimed at presenting a laboratory exercise focusing (a) on a very challenging therapeutic strategy, i.e. SARS-CoV-2 diagnostics, and (b) on technologies that are playing a central role in applied biochemistry and molecular biology, i.e. PCR and RT-PCR. The aims of the practical laboratory were to determine: (a) the possibility to identify SARS-CoV-2 sequences starting from a recombinant plasmid and (b) the possibility to discriminate cells with respect to the expression of SARS-CoV-2 Spike protein. This activity is simple (cell culture, RNA extraction, RT-qPCR are all well-established technologies), fast (starting from isolated and characterized RNA, few hours are just necessary), highly reproducible (therefore easily employed by even untrained students). We suggest that this laboratory practical exercises should be considered for face-to-face teaching especially if the emergency related to the COVID-19 pandemic is maintained. The teaching protocol here described might be considered in order to perform fast but meaningful in-presence teaching, making feasible the division of crowded classes in low-number cohorts of students, allowing the maintenance of the required social distance.

PMID:35385518 | DOI:10.1371/journal.pone.0266419

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Teaching during COVID-19 pandemic in practical laboratory classes of applied biochemistry and pharmacology: A validated fast and simple protocol for...

The GlobalBiochemical Diagnostic Reagent Marketis growing steadily and has shown promising growth over the last few years. The market is estimated to witness significant growth over the next 10 years.The report on the global market for Biochemical Diagnostic Reagent offers a comprehensive overview of the current market situation and future prospects of the market. The report segments the market on the basis of type, application regions and companies. The type segment is further subdivided into Liquid Double Reagent, Dry Powder Double Reagent. The geographical segment is divided into North America, Europe, Asia Pacific, and Rest of the World. The report provides market size and forecast for the global market and the segments mentioned above.Additionally, the development of new technologies and the rise of the economies in emerging markets are contributing to the growth of the global market. In the last few years, there has been a rapid increase in innovation, as well as a high adoption of technology, which has led to various changes in the strategy by the companies.

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Key Players mentioned in the report are:Randox, Beijing Strong Biotechnologies, KAINOS Laboratories, Beckman Coulter, FosunPharma, Sysmex, Siemens Healthineers, Beijing Leadman Biochemistry, Dojindo Laboratories, Roche, BioSino

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http://www.readmarketresearch.com/sample-request/175272-global-biochemical-diagnostic-reagent-market

The report segments the global Biochemical Diagnostic Reagent market as follows:

Global Biochemical Diagnostic Reagent Market: By Type

Liquid Double ReagentDry Powder Double Reagent

Global Biochemical Diagnostic Reagent Market: By Application

HospitalClinicLaboratory

Global Biochemical Diagnostic ReagentMarket: Regional Analysis

North America

U.S.Canada

Europe

GermanyU.K.FranceItalySpain

Asia Pacific

ChinaJapanIndiaAustraliaSouth Korea

Latin America

BrazilMexico

Middle East and Africa

South AfricaSaudi Arabia

TheBiochemical Diagnostic Reagent report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, types, and applications.

The report is a compilation of first-hand information, qualitative and quantitative assessment by industry analysts, inputs from industry experts and industry participants across the value chain. The Biochemical Diagnostic Reagent report provides in-depth analysis of parent market trends, macro-economic indicators and governing factors along with market attractiveness as per segments. The report also maps the qualitative impact of various market factors on market segments and geographies.

Report Highlights:

Key Questions Answered:

Major Key Benefits of the Report:

Get Flat $1000 Discount:Biochemical Diagnostic Reagent Market with COVID-19 Impact Analysis by Product Type (Liquid Double Reagent, Dry Powder Double Reagent), Application (Hospital, Clinic, Laboratory) ,Regional Forecast to 2028

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Biochemical Diagnostic Reagent Market Potential Growth, Share and Analysis of Key Players| Randox, Beijing Strong Biotechnologies, KAINOS Laboratories...

The Department of Chemistry & Biochemistry at Northern Arizona University invites applications for an Assistant Professor of Practice in Brewing and Fermentation Science. This position is an academic-year appointment beginning in mid-August 2022. This position is not eligible for tenure. The salary range is $62,000 to $71,000.

Minimum qualifications include (1) an earned Bachelors degree in brewing science, food science, or a related field, or a bachelors degree in a non-related field and completion of a professional or university-affiliated brewing program; (2) at least three years of work experience in a commercial brewing (or similar) facility with at least one year in a supervisorial role (brewmaster, head brewer, brewing supervisor, packaging manager, quality manager, tap room operations manager, or other documented work experience).

Preferred qualifications include (1) Masters degree or higher in a brewing science or related field (chemistry, biochemistry, microbiology, biological sciences, engineering, food science, etc.); (2) Prior teaching experience and evidence of teaching effectiveness in higher education in chemistry or other brewing science related fields; (3) Experience in differentiated instruction for diverse student populations; (4) Research experience and a publication record in brewing science related disciplines; (5) Proven knowledge of brewing process operations including raw materials, fermentation process technology, and packaging operations. Five years or more work experience in a commercial brewing facility; (6) Certified Cicerone or BJCP Judge and prior beer judging experience and prior beer judging experience; (7) Demonstrated knowledge or experience in tap room operations, beer sales, or marketing.

The successful candidate will serve as the primary point of contact for the curriculum in the newly launched Brewing and Fermentation Science certificate program at NAU. This program integrates coursework from Chemistry and Biological Sciences with offerings in NAUs School of Hotel and Restaurant Management in the form of unique emphases in Brewing Quality Assurance and Brewing Management and Hospitality (https://nau.edu/cefns/brewing-and-fermentation-science). The successful candidate will provide excellent instruction in brewing science lectures and labs, including Principles of Brewing Science (CHM 310), Brewing Process Technology (CHM 311), Sensory and Quality Aspects of Beer/Lab (CHM 312/312L), and Beer Basics (HA 372), and the candidate may also be required to instruct courses in brewing science relevant fields as needed.A critical part of this roll will be coordinating internships for undergraduate students in the craft beer and brewing industry and bringing and developing strategic relationships is key. This person will represent NAU in engagement efforts with statewide and national industry trade groups in brewing as well as community partners.

To apply, go to Faculty and Administrator Openings at https://in.nau.edu/human-resources/current-job-openings/ and select job ID 606157. Your application must be submitted online to be reviewed and should include a single attachment that contains (1) a cover letter addressing the job description and preferred qualifications, 2) a current CV, (3) a statement of teaching interests and philosophy, (4) a statement of research interests and plans of scholarly activity, (5) a one-page DEIJ statement that addresses your values and/or philosophy, accomplishments, experiences, education and training in DEIJ, and (6) the names of three references. Save all items, in the order stated, and attach them in a single PDF or Word Document. You will also need to arrange for three letters of reference to be sent separately as an attachment to chemistry@nau.edu. Address questions to Dr. Brandon Cruickshank, Chair, Department of Chemistry and Biochemistry, PO Box 5698, Northern Arizona University, Flagstaff, AZ, 86011-5698, brandon.cruickshank@nau.edu, (928) 523-9602. Review of applications will begin 30 days after posting (April 21, 2022) and continue until the position is filled or closed.

Northern Arizona University is a 29,569-student institution with its main campus in Flagstaff, a four-season community of about 72,000 at the base of the majestic San Francisco Peaks. NAUs emphasis on undergraduate education is enhanced by its graduate programs and research as well as distance learning. All faculty members are expected to promote student learning and help students achieve academic outcomes. The university is committed to a diverse and civil working and learning environment. The Department of Chemistry & Biochemistry has 18 faculty committed to excellence in teaching and research. The department currently has over 250 undergraduate majors and offers a number of Bachelor and Master of Science degrees in chemistry including two ACS certified degrees. A 120,000 square foot Science and Health Building, opened in 2015, houses chemistry teaching and research activities. The department also operates laboratories in the 95,000 square foot Science Lab Facility which was completed in 2007.

Northern Arizona University requires satisfactory results for the following: a criminal background investigation, an employment history verification, and a degree verification (in some cases) prior to employment. You may also be required to complete a fingerprint background check. Additionally, NAU is required to participate in the federal E-Verify program that assists employers with verifying new employees right to work in the United States.

Northern Arizona University is a committee Equal Opportunity/Affirmative Action Institution. Women, minorities, veterans, and individuals with disabilities are encouraged to apply. NAU is responsive to the needs of dual career couples.

NAU affirms the importance and critical need for justice, equity, diversity, and inclusion (DEIJ) in higher education, and we seek to hire people with a strong track record of engagement with DEIJ in their professional endeavors. We require as part of your application a one-page DEIJ statement that addresses your values and/or philosophy, accomplishments, experiences, education, and training with DEIJ.

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Northern Arizona University - Chemistry Dept - Assistant Professor of Practice in Brewing and Fermentation Science - Brewbound.com Craft Beer Job...

Pre-clinical studies on how experimental drugs reduce opioid abuse, multiple studies of new cancer treatments and the testing of antiviral medications are just a few of the 13 projects for which Rowan University researchers were awarded grants this spring from New Jersey Health Foundation (NJHF).

Each year, NJHF awards grants to advance health research and innovation at New Jersey organizations. In 2022, Rowan researchers received more than $433,000 in the form of research and community health grants from NJHF.

Dr. Daniel Manvich, assistant professor in the Department of Cell Biology & Neuroscience at Rowan University School of Osteopathic Medicine, is using his $34,878 grant to learn how an experimental class of drugs reduces the rewarding effects of opioids.

Opioids affect the brain in part by increasing levels of dopamine, a neurotransmitter involved in the brains rewards systems. Dopamine binds to five proteins called dopamine receptors. In pre-clinical testing, experimental compounds that selectively targeted D3 receptors blocked abuse-related effects of opioids.

We know that D3 receptors are important for these drugs effects, but what we dont know, from a neuropharmacological or neurobiological perspective, are the precise mechanisms by which these drugs are reducing the impact of opioids, said Manvich. Theres value to figuring out how these drugs are working to achieve their therapeutic effects, because that can help us develop more effective and selective medications to bring to clinical trials.

With the NJHF grant, Manvich can now start unraveling these mechanisms by using a relatively new technique called in vivo fiber photometry, which makes use of biosensors that can program dopamine neurons to emit fluorescent light when they are activated.

This grant from New Jersey Health Foundation gives us the opportunity to get this brand-new equipment up and running at Rowan, Manvich said, thus enabling him to apply for more extensive funding from the National Institutes of Health for the next phase of his research.

We are proud to continue to support the valuable research and innovation of scientists and others throughout our state, explained George F. Heinrich, M.D., vice chair and CEO of New Jersey Health Foundation. We are energized by the potentially breakthrough science being performed at this outstanding organization.

Other Rowan faculty with new NJHF funding include:

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Studying how experimental drugs curb opioid abuse and more: Rowan researchers awarded 13 N.J. Health Foundation grants - Rowan Today

Every week, we update this list with new meetings, awards, scholarships and events to help you advance your career.If youd like us to feature something that youre offering to the bioscience community, email us with the subject line For calendar. ASBMB members offerings take priority, and we do not promote products/services. Learn how to advertise in ASBMB Today.

The International Union of Biochemistry and Molecular Biology is offering $500 to graduate students and postdocs displaced from their labs as a result of natural disaster, war or "other events beyond their control that interrupt their training." The money is for travel and settling in. Learn more and spread the word to those who could use assistance.

For scientists, information literacy skills are more important now than ever before. Students have many possible avenues to look for information, and navigating effectively to the best source can be overwhelming if they dont know where to start. For scientists and instructors to help students with this navigation, it is a great idea to work with a librarian. On April 14, from 14 p.m. Eastern, this workshop will cover forming collaborations between scientists and librarians. Register.

This in-person meeting will be held in Madison, Wisconsin. It'll bea unique, open, inclusive and interactive forum for the international and domestic research community working on ESCRT biology and be an effective learning environment for all participants, especially graduate students, postdocs and other researchers from diverse backgrounds.This meeting will bring together experts in disciplines as diverse as biophysics, plant biology, cell biology, biochemistry and structural biology from around the world to cover key aspects of ESCRT biology.Submit an abstract.Learn more in in this Q&A with with organizer Wes Sundquist.

The Department of Neuroscience and Center for Foundational Neuroscience Research & Education at West Virginia University will offer up to 10 summer internships of research-intensive training to diverse, competitive undergraduate students who are currently enrolled at a U.S. college or institution and have completed their second or third year. Interns participate in nine weeks of research, weekly journal clubs, a poster symposium, and activities. Benefits: research stipend of $4,000, plus a round-trip travel stipend of up to $500; a double-room in a residential hall; and access to state-of-the-art laboratories, libraries, and recreational facilities. Learn more and apply.

The ASBMB Annual Awards are given to outstanding professionals who have been recognized by their peers for contributions to their fields, education and diversity. The recipients will give talks about their work at the 2023 ASBMB Annual Meeting in Seattle.See eligibility criteria here.

This conference, to be held in person in Athens, Ga., will address the multitude of roles that the O-GlcNAc protein modification has in regulating nuclear and cytosolic proteins. It will bring together researchers from diverse fields to share their research, tools and experience in O-GlcNAc biology. The abstract deadline is April 26, and the early registration deadline is May 9. Submit an abstract.Learn more in this Q&A with organizers Gerald Hart and Lance Wells.

ASBMB Lipid Research Division Seminar Series

The ASBMB Lipid Research Division features the work of young investigators at noon Eastern on Wednesdays. If you are interested in presenting, please contactJohn Burke. Registeronce to access the whole series.

The next seminar on April 27 will feature Nirmalya Bag of the Indian Institute of Technology and Federico Gulluni of the University of Turin in Italy.

We were contacted by Caroline Mueller, assistant professor at Ohio University, about a survey for early-career medical educators. She wrote: "We hope that through this survey, we will identify the needs of early-career medical educators and develop appropriate resources for new faculty." Learn more and complete the survey by April 30.

The U.S. Department of Energy's Office of Science Graduate Student Research program is accepting applications until May 4. The program supports U.S. graduate students seeking to conduct part of their thesis research at a DOE national lab or host site with a DOE scientist. The program is open to Ph.D. students who are conducting their thesis research in targeted areas of importance to the DOE Office of Science. Learn more.

The 2020 documentary Coded Bias explores biases embedded into technology. These biases affect the behaviors, outputs and consequences of countless devices, tools and digital spaces and often lead to or perpetuate inequity. Self-driving cars, facial recognition software, motion-activated appliances, job applicant screens and algorithms used for medical decision making theyre only as good as the code that defines their functions. The film describes in chilling fashion numerous prejudicial and even dangerous outcomes caused by biases hard-wired into data-centric technologies, and it makes the case for systemic changes needed to safeguard users and hold the tech industry accountable. Interested? The ASBMB Women in Biochemistry and Molecular Biology Committee is hosting a screening and virtual panel discussion at 4 p.m. EDT on May 4. Committee member Meghna Gupta will moderate, and Jeff Kapler and Marina Holz will be panelists. The link to access the film will be sent to all registered attendees two weeks prior to the event. (The film also can be streamed on Netflix.) Register.

This in-person meetingin Kansas City, Mo., will showcasethe most recent insights into the cis-regulatory code, how cis-regulatory information is read out by transcription factors, signaling pathways and other proteins, how cellular diversity is created during development and how we can study this problem using cutting-edge genomics technology and computational methods.The meeting will simultaneously examine the problem from an evolutionary perspective: how cis-regulatory elements evolve, how regulatory variation affects gene expression and phenotypes, how these changes have shaped development and parallel evolution, and how noise affects regulatory circuits and their evolution. The abstract deadline for those who'd like to be considered for talks is May 6. The abstract deadline for poster presenters and the registration deadline is May 25.Submit an abstract.Learn more in this Q&A with two of the organizers.

This five-day conference will be held Aug. 1418 in person in Cambridge, Massachusetts, and online. It will be an international forum for discussion of the remarkable advances in cell and human protein biology revealed by ever-more-innovative and powerful mass spectrometric technologies. The conference will juxtapose sessions about methodological advances with sessions about the roles those advances play in solving problems and seizing opportunities to understand the composition, dynamics and function of cellular machinery in numerous biological contexts. In addition to celebrating these successes, we also intend to articulate urgent, unmet needs and unsolved problems that will drive the field in the future. Registration and abstract submission begins Nov. 1. Abstracts are due May 16. Learn more.

The Marion B. Sewer Distinguished Scholarship for Undergraduates offers financial support to students who demonstrate an interest in the fields of biochemistry and molecular biology and enhance the diversity of science. Students whose social, educational or economic background adds to the diversity of the biomedical workforce or who show commitment to enhancing academic success of underrepresented students are eligible. The scholarship provides up to $2,000 toward undergraduate tuition costs for one academic year and can be applied to fall or spring tuition of the year following scholarship award notification. Up to ten scholarships will be awarded each academic year. Applications by individuals from underrepresented groups are encouraged, although all qualified applicants will be considered without regard to race, gender, color, ethnicity or national origin. Apply.

The Oklahoma Cobre in Structural Biology at the University of Oklahoma is hosting its 10th annual structural biology symposium on June 16. Confirmed speakers include Hao Wu of Harvard University, Breann Brown of Vanderbilt University School of Medicine, Lorena Saelices of University of Texas Southwestern Medical Center, Satish Nair of the University of Illinois Urbana-Champaign and Erica Ollman Saphire of the La Jolla Institute for Immunology. Check here for details and to register.

The Journal of Science Policy & Governance, the United Nations Educational, Scientific and Cultural Organization and the Major Group for Children and Youth announced in February a call for papers for a special issue on "open science policies as an accelerator for achieving the sustainable development goals." The deadline for submissions is July 10. To help authors prepare their submissions, the group will be hosting a series of webinars (April 8 & 29, May 20, and June 10) and a science policy paper-writing workshop (March 2627). Read the call for submissions and learn more about the events.

Head to beautiful Denver, Colorado, for a summer experience as a PRIDE (Programs to Increase Diversity Among Individuals Engaged in Health-Related Research) scholar. PRIDE is an initiative of the National Heart, Lung and Blood Institute that trains junior faculty from underrepresented backgrounds and/or with disabilities to advance their scientific careers and make them more competitive for external research funding. The University of Colorado PRIDE (led by Sonia C. Flores, who also leads the ASBMB Minority Affairs Committee) is one of nine national PRIDE sites. Its focus is on the "impact of ancestry and gender on omics of lung and cardiovascular diseases" (which is why it's called PRIDEAGOLD). The program consists of two consecutive summer institutes (two and one week, respectively) that offer comprehensive formal instruction on multi-omics, data sciences and bioinformatics, with an emphasis on interpretations based on ancestry and/or gender; career development and grant-writing tools; pairing with expert mentors; and pilot funds to develop a small research project. Learn more.

This in-person meeting will be held Sept. 29 through Oct. 2 in Snowbird, Utah. Sessionswill cover recent advances and new technologies in RNA polymerase II regulation, including the contributions of non-coding RNAs, enhancers and promoters, chromatin structure and post-translational modifications, molecular condensates, and other factors that regulate gene expression. Patrick Cramer of the Max Planck Institute will present the keynote address on the structure and function of transcription regulatory complexes. The deadline for oral presentation abstracts is July 14. The deadline for poster presentation abstracts is Aug. 18.Learn more.

Most meetings on epigenetics and chromatin focus on transcription, while most meetings on genome integrity include little attention to epigenetics and chromatin. This conference in Seattle will bridge this gap to link researchers who are interested in epigenetic regulations and chromatin with those who are interested in genome integrity. The oral and poster abstract deadline and early registration deadline is Aug. 2. The regular registration deadline is Aug. 29.Learn more..

The ASBMB provides members with a virtual platform to share scientific research and accomplishments and to discuss emerging topics and technologies with the BMB community.

The ASBMB will manage the technical aspects, market the event to tens of thousands of contacts and present the digital event live to a remote audience. Additional tools such as polling, Q&A, breakout rooms and post event Twitter chats may be used to facilitate maximum engagement.

Seminars are typically one to two hours long. A workshop or conference might be longer and even span several days.

Prospective organizers may submit proposals at any time. Decisions are usually made within four to sixweeks.

Propose an event.

If you are a graduate student, postdoc or early-career investigator interested in hosting a #LipidTakeover, fill out this application. You can spend a day tweeting from the Journal of Lipid Research's account (@JLipidRes) about your favorite lipids and your work.

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Calendar of events, awards and opportunities - ASBMB Today

Reviewed by Jeffry Nichols, Associate Professor, Worcester State University on 6/1/21

Comprehensivenessrating:3see less

The material covered is fairly similar to other biochemistry textbooks, but does lack some of the details of a more comprehensive biochemistry text (i.e. Lehninger's text). This isn't a negative, just an observation. The order in which the concepts are presented is different, but again still fairly complete.

Content Accuracyrating:4

From what I could tell, the information is accurate. Examples appear to be unbiased and give good everyday correlations to biochemistry ideas.

Relevance/Longevityrating:3

The material for the basics and background for biochemistry are unlikely to change, so in that sense they are relevant. The way in which the material is presented, i.e. the formatting, does make it difficult to follow at times. The tables and figures are not always near the relevant text and often there are figures/tables that appear before the section in the text. Again, this could be a formatting issue.

Clarityrating:4

The text is easy to follow, avoids jargon for the most part (until it needs defining). As mentioned above, references to tables/figures are hard to follow and some tables/figures seem "stuck in" at random points. This hurts the clarity of the text while reading.

Consistencyrating:4

Each chapter sticks to a familiar layout and walks the student through the various topics in a coherent manner.

Modularityrating:3

Overall the text could be broken up, but again, possibly due to formatting, many of the links do not work, interrupting the flow, On all the end of chapter sections, I couldn't get any of the links to work, with a message about "to be developed" or "coming soon". This is unfortunate as these links could be great for further exploration and follow up assignments.

Organization/Structure/Flowrating:3

Yes, the organization is pretty good, although I think the introduction of electron transport and electrochemistry should come after an understanding of WHERE these molecules are coming from, i.e. metabolism, breakdown of sugars, fats, amino acids, etc. This doesn't make it "bad", just no my personal preference. And as mentioned previously, the plethora of tables/figures can be overwhelming when they don't always line up with the discussion of them in the text.

Interfacerating:2

Couldn't get the links to work--although it appears many of the links are "printed" after the end of entire book. So the material might be there, but as it is currently put together, it would be difficult for instructors or students to use these links effectively.

Grammatical Errorsrating:4

From what I can tell, the grammar is fine throughout the text.

Cultural Relevancerating:4

Again, from what I read, I didn't notice any insensitive or offensive parts. Examples were clear and highlighted the biochemical aspects without a need address social or other issues. (which could actually be good depending on the nature of the class and student's interest in how science touch many aspects of our lives)

I have hope for this book, but I couldn't readily tell if this book is being maintained or updated on a regular basis, or if it is just a framework for others to build upon. The organization isn't ideal, and there are problems with links and such, but the overall material and coverage looks pretty good.

Read more from the original source:
Biochemistry: Free For All - Open Textbook Library

The Epsilon variant is the name given to the B.1.427/B.1.429 lineages of the virus | Representative image

Seattle: Scientists have found that a variant of the coronavirus, dubbed the Epsilon strain, has more resistance to vaccines, thereby somewhat neutralising their effectiveness.

The mutations give this coronavirus variant of concern a means to totally evade specific monoclonal antibodies used in clinics and reduces the effectiveness of antibodies from the plasma of vaccinated people, said the University of Washingtons School of Medicine, one of the institutions involved in research into the Epsilon strain.

The project was led by David Veesler of UWs Department of Biochemistry, and Luca Piccoli and Davide Corti of Vir Biotechnology.

The Epsilon variant is the name given to the B.1.427/B.1.429 lineages of the virus, which was first discovered in the US in the summer of 2020.

Studies found that the ability of plasma to fight the virus from patients who had previously been infected with COVID-19 was reduced by about two to three and a half times when exposed to the Epsilon variant.

Epsilon mutations were responsible for rearrangements in critical areas of the spike glycoprotein, added the release from UW. Electron cryo-microscopy studies showed structural changes in these areas. Visualising these mutations help explain why antibodies had difficulty binding to the spike glycoprotein.

One of the three mutations in the Epsilon variant affected the receptor binding domain on the spike glycoprotein, added the university. This mutation reduced the neutralising activity of 14 out of 34 neutralising antibodies specific to that domain, including clinical stage antibodies.

The findings of the scientists have been published in the journal Science, where their research is explained in-depth.

The fast rise in the number of cases associated with the B.1.427/B.1.429 lineages led to their classification as a variant of concern by the US Centre for Disease Control, they added in their research paper.

Excerpt from:
Vaccines found to be less effective against Epsilon strain of COVID-19 | Times of Oman - Times of Oman

Haematology and biochemistry results in equines: Interpretation and significance will cover the standard haematology and biochemistry tests performed at most laboratories.

The latest free webinar hosted by the Webinar Vet will take a look at equine blood tests and what the results mean.

Haematology and biochemistry results in equines: Interpretation and significancewill look at the standard haematology and biochemistry tests performed at most UK laboratories and discuss interpretation with regards to organ systems and significance. Factors affecting certain parameters will be indicated as appropriate.

Haematology and biochemistry results in equines: Interpretation and significance is being presented by veterinary clinical pathologist Dr Stacey A Newton, an internal medicine and equine neurology expert. It is sponsored by Nationwide Labs.

Register for the webinar, on Wednesday, February 9, at 12.30pm (GMT).

Dr Stacey Newton, BVSc Cert EM (Int Med) PhD FRCPath MRCVS, qualified from the University of Bristol 1993. She obtained her certificate in equine medicine (internal medicine) at the University of Liverpool, and went on to do a PhD in equine neurology. This was mainly based on headshaking in horses and working with Dr Derek Knottenbelt. Part of the work was with Paul Eldridge, a Neurosurgeon at The Walton Hospital, Liverpool, and a specialist in trigeminal neuralgia. Newton obtained her Diplomat of the Royal College of pathologists in 2008 and then went on to do become a Fellow of the Royal College of pathologists in 2010. Newton is currently working at Nationwide as a senior veterinary clinical pathologist.

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Webinar to explore equine blood tests and what the results mean - Horsetalk.co.nz - Horsetalk

Ashley Utz knows that over-the-counter medications like Prilosec and Prevacid are typically used to treat ulcers, reflux and other common stomach disorders. But the senior biochemistry major has a theory that these drugs, known as proton-pump inhibitors (PPI), could also help destroy cancer cells.

Tomorrow, along with more than 100 of her University of Mary Washington peers, Utz will share this trailblazing research, which shes toiled away on in Jepson Science Center labs for the past year, in the midst of a global pandemic. The 15th annual UMW Research and Creativity Symposium, held virtually again this year due to COVID-19, will put a spotlight on one of Mary Washingtons top priorities: undergraduate research. Featuring PDF posters and oral synopses on video, Thursdays presentations will span disciplines from science to sociology, math to music and classics to communication and will remain accessible through Friday for questions and comments.

When students discover how to pursue and investigate their own research questions, interpret the information they uncover and communicate their findings, it brings their learning to life and puts the knowledge and skills theyve gained into practice, said College of Arts and Sciences Assistant Dean Betsy Lewis, who described her own undergraduate research experiences as life-changing.

Last year was an experiment, said Lewis, who was in charge of moving the event online when Mary Washington suddenly switched to remote learning last spring. But she hailed the day as a success. The entire UMW community pulled together to support students.

Other schools showcase student research, she noted, but UMWs event is one of the longest running and widest reaching. Few universities cover so many disciplines in one symposium.

More than 70 projects submitted by nearly 150 students explore topics from music therapy to Middle Eastern immigration, from censorship to coffee bean growth, from accessibility in libraries to antifungal resistance, from resident curator programs to rural health care access. The projects were completed individually or in teams for coursework, senior capstones and departmental honors, while working in close consultation with, and often alongside, faculty with appropriate masking and social distancing.

COVID-19 inspired seniors Jenna Holland, Rachel Walters and Isabella Burns, who explored the impact of the pandemic on teachers in Nepal for their public sociology course. Under the mentorship of Associate Professor of Sociology Leslie Martin, the trio teamed up with three students enrolled at UMWs partner institution in the south Asian country, who helped them survey 107 educators in Kathmandu.

The teachers pandemic problems werent so different from their American counterparts, Burns said. Internet access was a common issue, and there was a clear dissatisfaction with remote technological devices. She recently joined Holland and Walters in penning a reflective essay of their cross-cultural learning experiences, which was published in the Undergraduate Journal of Service Learning & Community-Based Research.

Students like Utz have benefited from the types of high-impact learning opportunities offered at UMW. For the past four years, shes assisted Associate Professor of Chemistry Randall Reif with his research. Now, the tables have turned.

This project was so special because I was able to craft it entirely myself, with my professors guidance, said Utz, who hopes her findings will contribute to existing knowledge about the drugs doctors have at their disposal to treat cancer. PPIs are currently used with chemotherapy, she said, but little research exists on their effectiveness as stand-alone anti-cancer agents. We hope our work will be one of many research efforts to answer that question.

Senior biochemistry major Ashley Utz is exploring whether over-the-counter drugs like Prilosec and Prevacid can be used as standalone anti-cancer agents.

Ashley Utz treats Jurkat cells, a model cell line for studying the effects of certain drugs on cancer. After graduating from UMW, she plans to pursue a Ph.D. in molecular and structural biochemistry at NC State University, and eventually, a career in cancer research.

Graduating next month, shell soon move on to North Carolina State University to pursue a Ph.D. in molecular and structural biochemistry, and eventually, a career in cancer research. But Utz is confident that her project will be in good hands, as shes training UMW sophomore Shreya Murali to take it over this summer.

While I may not continue with this particular research, Utz said, it will live on at UMW.

Related

Continue reading here:
UMW Symposium Spotlights Student Research and Creativity - News - University of Mary Washington

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Highlights of the Report:

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Data Bridge set forth itself as an unconventional and neoteric Market research and consulting firm with unparalleled level of resilience and integrated approaches. We are determined to unearth the best market opportunities and foster efficient information for your business to thrive in the market. Data Bridge endeavors to provide appropriate solutions to the complex business challenges and initiates an effortless decision-making process.We ponder into the heterogeneous markets in accord with our clients needs and scoop out the best possible solutions and detailed information about the market trends. Data Bridge delve into the markets across Asia, North America, South America, Africa to name few.Data Bridge adepts in creating satisfied clients who reckon upon our services and rely on our hard work with certitude. We are content with our glorious 99.9 % client satisfying rate.

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Bio-Based Itaconic Acid Market | Key Opportunities, Trends, Business Demand And Key Players Analysis | Itaconix Corporation, Qingdao Kehai...

The reportOn Bio-Based Itaconic Acid Market Provides status and outlook of global MarketWith major regions, from angles of manufacturers,product types and end industries. This report analyzes the top manufacturers inKey regions, and splits theBio-Based Itaconic Acid market by product type and applications/end industries.This report includes estimations of the market size in terms of value (USD million).The report offers an up-to-date analysis regarding the current global market scenario, latest trends,drivers, and the overall market environment.

Market Overview:

Bio-based itaconic acid market is expected to grow at a rate of 5.50% for the forecast period of 2020 to 2027. Data Bridge Market Research report on bio-based itaconic acid market provides analysis and insights regarding the various factors expected to be prevalent throughout the forecasted period while providing their impacts on the markets growth.The changing trend towards eco-friendly products due to growing awareness regarding green house emissions will help impact the bio-based itaconic acid market growth in the forecast period.

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Key objectivesof the Report:

The report provides in-depth information about profitable showing markets and analyzes the markets for the global Bio-Based Itaconic Acid market. It provides full information about new product launches, current developments, and investments in the global market. The report delivers an complete evaluation of market shares, strategies, products, and manufacturing capabilities of the top players in the global market.

Bio-Based Itaconic Acid Market Top Manufacturers :

The major players covered in the bio-based itaconic acid market report are Thermo Fisher Scientific., Itaconix Corporation, Qingdao Kehai Biochemistry Co., LTD., AEKYUNG PETROCHEMICAL Co., Ltd, Zhejiang Guoguang Biochemistry Co.,Ltd., Spectrum Ultimate Chem India Pvt. Ltd, Alpha Chemika, Haihang Industry Co., Ltd, Ronas Chemicals Ind. Co., Ltd., Hefei TNJ Chemical Industry Co.,Ltd., Alfa Aesar, Merck KGaA, Choice Organochem Llp., FUSO CHEMICAL CO., LTD., Henan Haofei Chemical Co.,Ltd., Chemical Manufacturing Corp and FUJIFILM Wako Pure Chemical Corporation, among other domestic and global players. Market share data is available for global, North America, Europe, Asia-Pacific (APAC), Middle East and Africa (MEA) and South America separately. DBMR analysts understand competitive strengths and provide competitive analysis for each competitor separately.

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The report also examines the several volume trends, the pricing history, and the market value in addition to understanding the key dynamics of theBio-Based Itaconic Acid market.The Report Provides analysis of the key segments of the industry. This analysis sheds light in the current trends and opportunities in the Bio-Based Itaconic Acid Market.

TOC of The Report :

Executive Summary

Market Landscape

Five Forces Analysis

Market Segmentation by Product

Geographic Landscape

Vendor Analysis

Appendix

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About Us:

Data Bridge set forth itself as an unconventional and neoteric Market research and consulting firm with unparalleled level of resilience and integrated approaches. We are determined to unearth the best market opportunities and foster efficient information for your business to thrive in the market. Data Bridge endeavors to provide appropriate solutions to the complex business challenges and initiates an effortless decision-making process.We ponder into the heterogeneous markets in accord with our clients needs and scoop out the best possible solutions and detailed information about the market trends. Data Bridge delve into the markets across Asia, North America, South America, Africa to name few.Data Bridge adepts in creating satisfied clients who reckon upon our services and rely on our hard work with certitude. We are content with our glorious 99.9 % client satisfying rate.

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Bio-Based Itaconic Acid Market | Industry Size, Share, Key Players, Trends, and Growth Forecast | Thermo Fisher Scientific., Itaconix Corporation,...

Tomato is a globally strategic crop and consumers need it throughout the year. To have a healthy and productive tomato plant, a high-quality seedling is a necessity. Toward this end, the current research was to improve a system for producing tomato seedlings in plant factories using light-emitting diodes (LEDs).

The results indicated that tomato seedlings of both cultivars under (Red 70% + Blue 30%) showed the greatest plant height and the largest total leaf area. The best treatment for the accumulation of soluble protein and soluble sugar contents for Gangmu No.1 and Millennium cultivars were (Red 50%+Green 20%+ Blue 30%) and Red 100%, respectively. The Non-Photochemical Quenching under (Red 50%+Green 20%+ Blue 30%) treatment was the lowest for Gangmu No.1, while it was the lowest under white fluorescent light for Millennium. The electron transport rate under white fluorescent light treatment was the highest for Gangmu No.1, while it was the highest under (Red 70% + Blue 30%) for Millennium.

The results indicated that the mixture of red and blue at (Red 70% + Blue 30%) was beneficial for the growth of tomato seedlings for both cultivars, which could be efficiently used in plant factories and provide some data for different LED light ratios applicable in a closed system to demonstrate how to get the best lighting conditions for tomato seedlings.

Read the complete research at http://www.researchgate.net.

Yousef, Ahmed & Xu, Yong & Chen, Faxing & Lin, Kui & Zhang, Xiwen & Guiamba, Hellio & Ibrahim, Muhammed & Rizwan, Hafiz & Ali, Muhammad. (2021). The influence of LEDs light quality on the growth pigments biochemical and chlorophyll fluorescence characteristics of tomato seedlings (Solanum lycopersicum L.). Fresenius Environmental Bulletin. 30. 3575-3588.

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Study on the influence of LEDs light quality on the growth pigments biochemical and chlorophyll fluorescence characteristics of tomato seedlings -...

5 July 2021, 14:15 | Updated: 5 July 2021, 15:30

Students have told LBC they are "infuriated" at plans from some universities to continue teaching parts of their course online, even as Boris Johnson is set to announce plans for all social distancing rules to be removed.

Multiple universities including Kent, Sheffield and University College London have already made public that students should expect "blended learning" - with some lectures given online.

Hundreds of students have signed a petition at Kent University after they said group lectures would continue online next year with the aim of reverting to in-person "in early 2022".

Manchester University has gone further, announcing a permanent move to including online teaching in their courses, including for "explanatory material" that would previously have been given in lecture theatres.

But despite promises of more in-person teaching, after over a year of watching lectures from their bedrooms students have told LBC they are thoroughly opposed to the plans and have little trust in university management.

Biochemistry first-year student Caitlin Wright told LBC she has only had four hours of in-person teaching in her first year at Manchester University.

"Labs have been taught by YouTube tutorials and when people went in to do one they had no idea what to do and how to use the equipment," she recounted.

Caitlin described the decision by Manchester to move to permanently include online teaching as part of the courses as "absolutely shocking and not in the best interests of students".

"I understand why it was necessary for this year but past the pandemic I am not sure why it is necessary.

"Everyone learns so much better in person, where they can bounce ideas off each other and put their hands up to ask questions. Online it takes three to five business days to get an answer to your question."

Read more: Manchester students claim police are carrying out 'random' Covid-19 checks in halls

Similarly, first-year Politics student Chris Adair told LBC he is worried the "quality of teaching will be severely affected if the university use the pandemic as an excuse to move to online teaching".

While the university says using a hybrid approach will allow students more flexibility, Chris told LBC he did not understand this as "many lectures were already recorded" pre-pandemic.

Chris said he and other students are "very, very worried" that the university could again move back to fully-online teaching.

"Last year they promised there would be blended learning and they reneged on that in the fist few weeks. There is uncertainty and real distrust between students and management."

Read more: Manchester Uni students pull down lockdown fencing put up around halls

Nick Hillman, Director of the Higher Education Policy Institute, told LBC universities have been scarred by the chaos of last autumn and are adapting their plans accordingly.

"Students regard learning as a social endeavour and see part of the university experience as spending time in the presence of people from other countries, other parts of the UK and other backgrounds," he explained.

"But universities got it wrong last year, when they promised face-to-face learning would come back earlier than it was allowed to for most students, and they are desperate not to overpromise this year."

Unlike Manchester, the University of Sheffield have not said they will be moving to blended learning permanently, but will adapt their learning to include online teaching "should this be necessary".

Sheffield say their "expectation and current plan is to deliver as much face-to-face teaching as possible in 2021-22", but students are concerned that they have heard nothing concrete from the university so far.

"I have only had 45 minutes of actually being at university, one in-person seminar the entire year," Politics student Dan Walsh told LBC.

"I would be hoping for an approach that is blended but also returns teaching to what it is meant to be," they continued.

"My course is meant to have 10 weeks of teaching but the university is saying because it is online only five weeks is needed.

"We're getting half the teaching for 9,000. That's not fair, that's not just."

Ahead of Boris Johnson's announcement that all sectors of the economy will now be able to open up, Dan added: "What difference is it going to make if we don't have in-person teaching if everyone is going to the pubs and clubs. It's pretty futile."

Explained: What time is Boris Johnson's announcement and what will he say?

Responding to the student's concerns, a University of Manchester spokesperson told LBC: This is not online teaching, but aboutaugmenting in-person lectures, seminars, labs, Q&As and discussions, and workshops with high quality online materials for self-study.

"We have been speaking to students for some time about ways to increase flexibility and choice and we will continue to do so to help shape this activity to their needs and the needs of each discipline.

"Our commitment to blended and flexible learning is part of the university strategy.

A University of Sheffield spokesperson said they "are working hard to provide the best on-campus experience in a Covid-secure way, in line with government guidelines.

Our top priority is always the wellbeing of our university community. Our expectation and current plan is to deliver the great majority of teaching face-to-face in September, with some larger lectures being delivered online.

"However, we have proven expertise in providing blended learning over the past year and will be able to adapt our learning and teaching delivery in response to new Covid-19 safety measures should this be needed.

"Digital delivery has opened up many possibilities for enhanced innovative learning and virtual social activities over the past year.

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Student fury as universities plan to continue online teaching into 2022 - LBC