Global D-Alanine Market 2017- Taizhou Tianhong Biochemistry, Zhangjigang Specom, Huachang Pharm – Invest Daily News: Market Research News by…

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Global D-Alanine Market 2017- Taizhou Tianhong Biochemistry, Zhangjigang Specom, Huachang Pharm - Invest Daily News: Market Research News by...

Laboratory Biochemical Reagent Market 2019 Manufacturer Landscape, Revenue and Volume Analysis and Segment Information upto 2025 – Melanian News

Biochemical Reagents designates chemical substances meeting standards of purity that ensure the scientific precision and reliability of chemical analysis, chemical reactions or physical testing.Today, clinical diagnosis needs could be fulfilled with the use of biochemical analyzer, which is expected to detect a number of projects that cannot be detected with the help of traditional biochemical methods. Considering the development of biochemical tests being highly related to a nations healthcare improvement, biochemical detection could be a critical part of clinical testing.

Global Laboratory Biochemical Reagent Market Research Report 2019-2025 document provides an explicit outline and the concepts of the dynamic in the global Laboratory Biochemical Reagent market. The report highlights fundamental frameworks of the market, giving the exhaustive combination between past and current market trends to forecast future market values and tendencies of the market. The report helps readers track and understand market competitor strategies, market size, price, volume, values, supply, and global demand and all of the economic factors surrounding. Overall research report underlines value in terms of sectional review as well as evaluates the global market across regional levels and from a global viewpoint.

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Laboratory Biochemical Reagent Market 2019 Manufacturer Landscape, Revenue and Volume Analysis and Segment Information upto 2025 - Melanian News

Putting wildlife at top of agenda: Liz Bonnin talks ahead of Planet Earth II live show coming to Birmingham – shropshirestar.com

The series was announced by the BBC in 2013 and focused on Islands, Mountains, Jungles, Desserts, Grasslands and Cities. More than 11 million people tuned in.

Sir David Attenborough closed the series by saying: Now, over half of us live in an urban environment. My home, too, is here, in the city of London. Looking down on this great metropolis, the ingenuity with which we continue to reshape the surface of our planet is very striking. But its also sobering. It reminds me of just how easy it is for us to lose our connection with the natural world. Yet, its on this connection that the future of both humanity and the natural world will depend. And surely, it is our responsibility to do everything within our power to create a planet that provides a home not just for us, but for all life on Earth.

The series was described as being undoubtedly the greatest TV nature documentary to date and theres a strong case for it being one of the best TV series full stop. It won numerous awards and is now being recreated live in concert with Planet Earth Live II.

BBC Studios and the acclaimed BBC Natural History Unit has announced a UK & Ireland arena tour for Spring 2020. Fans can experience sensational footage from the BAFTA and EMMY award winning BBC series, with the show promising to bring audiences closer to the planets spellbinding animals, landscapes and wildlife dramas than ever before.

Following on from the recent success of the 2019 Blue Planet II Live In Concert tour, the live concerts will feature breathtaking, specially-selected footage shown in 4K ultra high-definition on a gigantic LED screen, as the City Of Prague Philharmonic Orchestra, conducted by Matthew Freeman, play the remarkable music by Oscar winner Hans Zimmer, Jacob Shea & Jasha Klebe for Bleeding Fingers Music.

The arena tour will visit Birminghams Resorts World Arena on April 3.

Zimmer is renowned for his work on the likes of Gladiator, Interstellar and Blade Runner 2049, but said that the landmark BBC series stood out amongst his work. Planet Earth II is one of the most amazing things Ive ever been involved in: some of the greatest action scenes ever put on film, some of the most emotional, epic, fragile scenes Ive ever witnessed. Filmmaking at its absolute peak.

In the spectacular live show, audiences across the UK will get to rub shoulders with our acrobatic primate cousins in the steaming jungles of Madagascar, race alongside fearsome hunting lions in the remote sandy deserts of Namibia, face stormy Antarctic seas with a family of penguins and feel the raw tension as a baby iguana tries to escape the clutches of deadly racer snakes. And they will no doubt tap their toes along with dancing grizzly bears and be swept away by the bravery of a mother snow leopard.

The Planet Earth II Live in Concert arena tour will be hosted by wildlife and natural history TV presenter Liz Bonnin. With a masters in wild animal biology, Bonnin has presented over 40 primetime programmes including Blue Planet Live, Super Smart Animals, Galapagos and Horizon.

With her recent landmark BBC One documentary Drowning in Plastic, she investigated the ocean plastic crisis, with her hard-hitting environmental reporting raising the level of public debate on this important topic. Bonnin also regularly speaks at and hosts science and natural history events across the country, including the National Science + Engineering Competition, the Natural History Museums Wildlife Photographer of the Year Awards, New Scientist Live and Blue Dot Festival.

She said: I am so honoured to have the role of host on the Planet Earth II Live in Concert arena tour. The TV series included some absolutely breathtaking sequences who can ever forget the marine iguana fighting for its life as it escaped those racer snakes? I will be just as thrilled as the audience to relive such magnificent scenes on the giant screen, accompanied by a spectacular 80-piece orchestra it will certainly be an experience to remember.

Mat Way, Global Director, Live Entertainment at BBC Studios, added: After the very successful Blue Planet II tour we are delighted to partner with FKP Scorpio once again and bring Planet Earth II Live In Concert to the UK & Irish arenas, an incredible production bringing the BBCs ground breaking footage to the stage for fans to enjoy

Bonnin had always been interested in biology and chemistry at school, and she went on to study Biochemistry at University. After graduating, she started a career as a TV presenter working on such shows as BBC Ones Top of the Pops, before returning to her first love, science, and completing a Masters in Wild Animal Biology and Conservation. Bonnins main interests during her studies were animal behaviour and intelligence and big cat conservation. She set up and carried out a research project on the diet of tigers in Bardia National Park, Nepal, which saw her come first in her class.

Bonnins TV career has drawn heavily on her academic expertise. Recently, Bonnin has co-presented BBC Ones Blue Planet Live and the ground-breaking documentary Drowning in Plastic. She has also presented Should We Close Our Zoos in the latest series of Horizon and Big Animal Surgery, both for BBC Two.

She has previously been on our screens presenting the BBC One series Galapagos and Wild Alaska Live following the hugely successful Big Blue Live series in Monterey, California for the BBC, and for PBS in the USA.

Bonnin has also appeared in the series of Who Do You Think You Are? on BBC One and presented a wildlife series for BBC One about animal migrations called Natures Epic Journeys. Other TV credits include wildlife and animal behaviour programmes Super Smart Animals, Animals in Love, Animals through the Night: Sleepover at the Zoo, Operation Snow Tiger and Animal Odd Couples; science series Horizon, Stargazing Live and Bang Goes the Theory; documentaries Egypts Lost Cities, Museum of Life and Science Friction; and ITVs popular Countrywise.

In addition to her TV work, Bonnin has hosted various high profile events, including the UKs National Science and Engineering Competition Awards and the Natural History Museums prestigious Wildlife Photographer of the Year Awards. She was also recently awarded an Honorary Fellowship of the British Science Association.

When I got the call to do this, I jumped at the chance. I was onboard immediately. Quite selfishly, Im looking forward to the experience myself just as much as other members of the audience will be.

The thought of seeing that footage on such a big screen and having a live 70-piece orchestra will be magnificent. Ive seen some of the programmes on big screen and its a complete game changer. For me, its a kind of spiritual experience. For people who dont work in wildlife, these creatures remind us of our connection to nature. Then to see that while hearing music from Hans Zimmer is emotional. Its one of those rare occasions where we can celebrate the plant and humanity itself.

Bonnins role is to take the audience by the hand and keep the talking to a minimum. She wants the music and visuals to work their magic.

So Ill put into context the scenes and Ill give them new unexpected information about the scenes. And then the exec producer of Planet Earth II will come on every now and then to give them insights into what it took the make the scene work. Therell be little fun facts and well have 16 sequences, some are compilations that weve prepared that work well together. Of course they include the racer snake and iguana. We have hummingbirds, penguins, snow leopards. Weve cherry picked stuff that lends itself to them.

Bonnin describes hosting the show as a dream gig. She fell into a career that she adores and hopes to effect change. I do feel theres a very good quote going round. If youre not part of the solution youre part of the problem. The younger generation are making their voices heard more loudly than mine. Considering whats happening to the planet we should all be environmentalists. My role is to spell out what conservationists are doing. So when Im making programmes like Drowning in Plastic, Im a human being who has to play a part in being part of the solution.

This concert plays a role in that. It will really move us all to feel inspired and feel motivated to play our part. I dont need to preach, the images will remind us of the magic of the wildlife. I want to leave the audience with messages of hope and inspiration. We can save our wildlife and ourselves and become better custodians.

Bonnin is a communicator who wants to spell out inconvenient truths. In addition to Planet Earth II Live, she has recently finished a documentary on the impact of meat production on our environment.

These are reminders that we need to think about how much we consume. Its about all of these resources that we take for granted.

Given her success, its remarkable that Bonnin didnt want to do TV. Its been a wonderful blessing but it wasnt part of the plan. Im extending myself without going back to school. I really hope some of my work opens peoples eyes as much as it did mine.

Bonnin grew up amid nature, living in the mountains in the south of France, above Nice. She played outdoors all the time and spotted hedgehogs and snakes and spiders. She fell in love with nature.

I was plonked in the middle of it. Nature worked its magic around me. I always wanted to understand how that everything worked, down to the smallest layer. When I discovered chemistry and biology and biochemistry in school, I was thrilled. You can understand everything down to the atoms. When I listen to the processes in the human body, you realise were extraordinary, the way cells do things is incredible.

I did a bit of telly after uni, then went back to school. After biochemistry neuro degenerative diseases was going to be my PHD. I had done some zoology by then and knew I was passionate about wanting to protect wildlife. My masters set me off on a different path.

Bonnin doesnt see her work as being a job. Instead, she feels very privileged to continue to learn from all the scientists and conservations working night and day to save our planet. I do a lot of talks in schools and its important to care and to play their role in protecting the planet. I feel very lucky to be doing it.

Theres never been a time in our history when people like Greta Thunberg and people who organise protests like Extinction Rebellion have not tried to make their voices heard. Theres a zeitgeist there and so people are more aware and more conscious than ever before.

Greta is a hero of mine, no question. She sat outside parliament in Sweden on her own and she has galvanised millions of people to make their voices heard. For the first time in human history on a global level we are impassioned enough to say enough is enough. I feel ashamed as an adult that young children are doing this. We should have taken better care of their future. Among all the pretty dire news about climate, plastic and biodiversity I am hugely inspired that the beauty of the human spirit can turn this around. But my God have we left it late.

Greta isnt Bonnins only hero. There are others she admires. Sir David Attenborough is my absolute hero. Sylvia Earle, the marine biologist and author, and Alexandra Cortez, a congresswoman in New York who ran with no corporate funding, are also heros. Alexandra is a powerhouse of a woman who stood by the strength of her convictions. Just like Bonnin.

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Putting wildlife at top of agenda: Liz Bonnin talks ahead of Planet Earth II live show coming to Birmingham - shropshirestar.com

An Astrobiologist Seeks to Explain Whether There Are Other ‘Beings’ Amongst Us – Qrius

Samantha Rolfe, University of Hertfordshire

Life is pretty easy to recognise. It moves, it grows, it eats, it excretes, it reproduces. Simple. In biology, researchers often use the acronym MRSGREN to describe it. It stands for movement, respiration, sensitivity, growth, reproduction, excretion and nutrition.

But Helen Sharman, Britains first astronaut and a chemist at Imperial College London, recently said that alien lifeforms that are impossible to spot may be living among us. How could that be possible?

While life may be easy to recognise, its actually notoriously difficult to define and has had scientists and philosophers in debate for centuries if not millennia. For example, a 3D printer can reproduce itself, but we wouldnt call it alive. On the other hand, a mule is famously sterile, but we would never say it doesnt live.

As nobody can agree, there are more than 100 definitions of what life is. An alternative (but imperfect) approach is describing life as a self-sustaining chemical system capable of Darwinian evolution, which works for many cases we want to describe.

The lack of definition is a huge problem when it comes to searching for life in space. Not being able to define life other than well know it when we see it means we are truly limiting ourselves to geocentric, possibly even anthropocentric, ideas of what life looks like. When we think about aliens, we often picture a humanoid creature. But the intelligent life we are searching for doesnt have to be humanoid.

Sharman says she believes aliens exist and theres no two ways about it. Furthermore, she wonders: Will they be like you and me, made up of carbon and nitrogen? Maybe not. Its possible theyre here right now and we simply cant see them.

Such life would exist in a shadow biosphere. By that, I dont mean a ghost realm, but undiscovered creatures probably with a different biochemistry. This means we cant study or even notice them because they are outside of our comprehension. Assuming it exists, such a shadow biosphere would probably be microscopic.

So why havent we found it? We have limited ways of studying the microscopic world as only a small percentage of microbes can be cultured in a lab. This may mean that there could indeed be many lifeforms we havent yet spotted. We do now have the ability to sequence the DNA of unculturable strains of microbes, but this can only detect life as we know it that contain DNA.

If we find such a biosphere, however, it is unclear whether we should call it alien. That depends on whether we mean of extraterrestrial origin or simply unfamiliar.

A popular suggestion for an alternative biochemistry is one based on silicon rather than carbon. It makes sense, even from a geocentric point of view. Around 90% of the Earth is made up of silicon, iron, magnesium and oxygen, which means theres lots to go around for building potential life.

Silicon is similar to carbon, it has four electrons available for creating bonds with other atoms. But silicon is heavier, with 14 protons (protons make up the atomic nucleus with neutrons) compared to the six in the carbon nucleus. While carbon can create strong double and triple bonds to form long chains useful for many functions, such as building cell walls, it is much harder for silicon. It struggles to create strong bonds, so long-chain molecules are much less stable.

Whats more, common silicon compounds, such as silicon dioxide (or silica), are generally solid at terrestrial temperatures and insoluble in water. Compare this to highly soluble carbon dioxide, for example, and we see that carbon is more flexible and provides many more molecular possibilities.

Life on Earth is fundamentally different from the bulk composition of the Earth. Another argument against a silicon-based shadow biosphere is that too much silicon is locked up in rocks. In fact, the chemical composition of life on Earth has an approximate correlation with the chemical composition of the sun, with 98% of atoms in biology consisting of hydrogen, oxygen and carbon. So if there were viable silicon lifeforms here, they may have evolved elsewhere.

That said, there are arguments in favour of silicon-based life on Earth. Nature is adaptable. A few years ago, scientists at Caltech managed to breed a bacterial protein that created bonds with silicon essentially bringing silicon to life. So even though silicon is inflexible compared with carbon, it could perhaps find ways to assemble into living organisms, potentially including carbon.

And when it comes to other places in space, such as Saturns moon Titan or planets orbiting other stars, we certainly cant rule out the possibility of silicon-based life.

To find it, we have to somehow think outside of the terrestrial biology box and figure out ways of recognising lifeforms that are fundamentally different from the carbon-based form. There are plenty of experiments testing out these alternative biochemistries, such as the one from Caltech.

Regardless of the belief held by many that life exists elsewhere in the universe, we have no evidence for that. So it is important to consider all life as precious, no matter its size, quantity or location. The Earth supports the only known life in the universe. So no matter what form life elsewhere in the solar system or universe may take, we have to make sure we protect it from harmful contamination whether it is terrestrial life or alien lifeforms.

So could aliens be among us? I dont believe that we have been visited by a life form with the technology to travel across the vast distances of space. But we do have evidence for life-forming, carbon-based molecules having arrived on Earth on meteorites, so the evidence certainly doesnt rule out the same possibility for more unfamiliar life forms.

Samantha Rolfe, Lecturer in Astrobiology and Principal Technical Officer at Bayfordbury Observatory, University of Hertfordshire

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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An Astrobiologist Seeks to Explain Whether There Are Other 'Beings' Amongst Us - Qrius

Love Aaj Kal Twitter Reactions: Looking in the adorable biochemistry of Karthik Aryan and Sara Ali Khan, the fans said & # 039; the movie will…

The trailer of Bollywood star Karthik Aaryan and Sara Ali Khan's film Love Aaj Kal was circulated because of the manufacturers today. Karthik and Sara's chemistry when you look at the truck associated with movie therefore the tip involving the two, Jhok followers are extremely much liked. Apart from Karthik and Sara, an innovative new face can also be noticed in this truck filled with love and psychological crisis.

->The title of the brand new face is Arushi Sharma and after seeing Arushi into the movie, the followers will also be desperate to find out about all of them. But before that, why dont we let you know that after viewing the trailer of 'Love Aaj Kal', the viewers has begun providing different responses on social networking. More followers have actually congratulated Karthik and Sara's love biochemistry on the movie 'Love Aaj Kal'. And additionally stated that the movie would turn out to be a blockbuster in the box-office.

In the film 'Love Aaj Kal', directed by Imtiaz Ali, the complete tale of exactly how love and wrangling between Karthik and Sara are placed on the major display screen from 1990 to 2020. How Karthik gets drawn to Sara from schooling time and starts to fall-in love involving the two while they develop youthful. By the way in which, the followers were also keen to understand pair of Karthik and Sara in the silver screen for a long period plus in view of the similarity, the manufacturers have actually established the truck today. After viewing the truck, Twitter is highly praised and it has additionally expressed its reaction. Let's see:

Receiving Sara ???

In trailer you can view exactly how event shes going to take this film . Kuddos to my woman. Gonna shine harder #SaraAliKhan#LoveAajKalhttps://t.co/m5BR3lfIqs

-? (@saraXstan_kiddo) January 17, 2020

I LOVEEE THE TRUCK !! BOMBBB ???? #LoveAajKal

-? (@anilasayshi) January 17, 2020

It's a Sara's program. It's her program. Her character is bomb. It's a really different personality from exactly what I've previously seen. Love her scenes when you look at the truck. Nailing it. ?I have actually alot to express about anything else but I'll hold it to myself. Positive vibes just.#LoveAajKal#SaraAliKhanhttps://t.co/QtD1gDa0JU

Ishita (@ ishita2301) January 17, 2020

Im enjoying the truck !! Omg something about Sara idk exactly what it really is. This girl could be the HEROINE. #LoveAajKal

Rima roentgen (@howudoin_r) January 17, 2020

No concealed definitions,Straight ahead story

Imtiaz Ali aag laga dega iss baar?#LoveAajKalpic.twitter.com/BeE4IjCihP

Kung Fu Fluffy (@That_FluffyGuy_) January 17, 2020

This love story will interact with childhood cool vibes im this film #LoveAajKal Going? will likely be awesome hit at box-office? ?????? https://t.co/F0xMTtdw3W

Deepak Rajgor? (@DeepakRajgor) January 17, 2020

Trailer of #LoveAajKal ???? This is likely to be an enjoyable movie. Imtiaz Ali is back My fav manager Kartik is impressive as well

Rakshith RK ?? (@RK_HUNTERR) January 17, 2020

Their chemistry ?????Littttttttttt ???? ? ? ? Babiesss ???????????????? #SaraAliKhan#KartikAaryan#LoveAajKalpic.twitter.com/sjRHbxBqku

-. (@crezy_virat_fan) January 17, 2020

Kartik Aaryan and Sara Ali Khan's film Love Aaj Kal are circulated in theaters on February 14. Randeep Hooda will additionally be noticed in a crucial role when you look at the movie.

Continued here:
Love Aaj Kal Twitter Reactions: Looking in the adorable biochemistry of Karthik Aryan and Sara Ali Khan, the fans said & # 039; the movie will...

Aliens could be living with us, says an astrobiologist – MENAFN.COM

(MENAFN - NewsBytes) A few weeks back, Helen Sharman, the first British astronaut, made the bold claim that aliens exist and could be living among us - completely undetected.

The remark drew widespread attention (given that it is ALIENS we are talking about), leading many to wonder how species from other worlds could survive without getting noticed.

Now, an astrobiologist has explained how that could be possible!

In an interview with The Observer, Sharman had said that "Aliens exist" and "there's no two ways about it."

She justified the assertion by saying, "There are so many billions of stars...that there must be all sorts of different forms of life . Will they be like you and me? Maybe not. It's possible they are here right now and we simply can't see them."

Following Sharman's remarks, Samantha Rolfe, from UK's Bayfordbury Observatory, published an editorial in The Conversation explaining how invisible alien life can actually exist on Earth.

Basically, the astrobiologist claimed that there is no fixed/complete definition of life (apart from what we see on Earth), which practically opens the possible form of an alien creature to thousands of interpretations, including the invisible one.

Most of the movies depicting aliens show them as humanoids or human-like creatures, which is enough in itself to explain that humans mostly limit alien life forms "to geocentric, possibly even anthropocentric, ideas of what life looks like," Rolfe added.

Rolfe added that if aliens are here on Earth, like Sharman said, they could be living in a microscopic "shadow biosphere" - which Earthlings can not see.

"By that, I don't mean a ghost realm, but undiscovered creatures probably with a different biochemistry," Rolfe wrote, adding that "we can't study or even notice them because they are outside of our comprehension."

In the same op-ed, Rolfe also suggested that microscopic alien life with silicon-based biochemistry, which is different from our carbon-and-nitrogen-based one, could have landed on Earth via a meteorite.

"[W]e do have evidence for life-forming, carbon-based molecules having arrived on Earth on meteorites," she wrote while implying that this could have also happened for "more unfamiliar life forms."

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Aliens could be living with us, says an astrobiologist - MENAFN.COM

To the stars and beyond: A hundred years of Isaac Asimov – Hindustan Times

In a completely unscientific survey I conducted for the express purpose of writing this article, I sent a WhatsApp message to many of my (what I hoped were) sci-fi reading friends asking what they thought Asimovs greatest work (or their favourite Asimov work) was. The answers did not surprise me; there was absolutely no consensus. Everyone who had read Asimov had a different answer. Bicentennial Man and End of Eternity FTW! replied one. Some would say the Robot stories, but Foundation is more in-depth, answered another. Robot Dreams, said a third; his short stories definitelyespecially the AI ones, pinged a fourth; Nightfall. No questions there! said a fifth with complete confidenceand so on.

Of course, there was also one who said whos Asimov? Horrified, I explained that he was an acclaimed writer whose work had been made into several movies. Havent you seen I, Robot? I asked. Is that the one with Rajinikanth? came the tentative reply.

Message received. Asimov isnt everyones cup of tea.

But for those of us who revel in the scientific accuracy of fantastic worlds, in the possibility of reimagining the mundane into never-impossible futures, and found ways of thinking about the Big Questions of life through the stories of Multivac and lands where stars were only seen once in a thousand years, Isaac Asimov is a prophet (peace be upon his name).

A Russian immigrant in the USA in the 1930s, a professor of biochemistry, a war veteran, and a writer of popular science books, Isaac Asimov whose birth centenary it was on 02 January was also, possibly, the most successful science fiction writer of his generation.

His mind-bending stories of inter-stellar travel, other worlds, strange encounters, and sentient machines have never stopped fascinating readers since he first put finger to typewriter. One of the most prolific of writers, he has authored more than 500 books, edited several volumes, and all of this while also being a professor of biochemistry.

Born in a village called Petrovichi in Smolensk, Russia somewhere between October 1919 and January 1920, Isaac Asimov decided to celebrate his birthday on 02 January. He wrote in In Memory Yet Green, It could not have been later than that... There is, however, no way of finding out. My parents were always uncertain and it really doesnt matter. I celebrate January 2, 1920, so let it be.

The Asimovs emigrated to the USA in 1922, and after struggling for three years, managed to save enough money to open a small candy store in New York. It was there that a young Isaac discovered science fiction in the form of magazines lying around in the store and also discovered the incomparable joy of reading and getting lost in the pages of a good book.

Isaac Asimov discovered he was a storyteller in school, and soon even before he had turned 12 was already trying his hand at writing them. He also wrote a detailed daily journal, complete with baseball scores, and had a dedicated following as a teller of tales he had read in magazines and books. But before he ever wrote science fiction, as a teenager, he had first tried his hand at fantasy.

In Its Been a Good Life a compilation of Asimovs diary entries, personal communications, and a condensation of his earlier autobiographies he writes about the first piece of fiction he ever attempted to write on the used typewriter his father had bought him: (it was a story of) a group of men wandering on some quest through a universe in which there were elves, dwarves, and wizards, and in which magic worked.

This was in the year 1935. Asimov was 15, and JRR Tolkiens The Hobbit wasnt published till 1937 (The Lord of Rings trilogy, which pretty much set the template for fantasy fiction for the next several decades, would only be published twenty years later between July 1954 and October 1955). It was as though I had some premonition of JRR Tolkiens Lord of The Rings, writes Asimov. But for better or worse, it didnt stick.

By the mid-1930s, Asimov was an avowed sci-fi fan, writing letters to science fiction magazines and even joining fab clubs. And by 1938, as an undergraduate chemistry major at Columbia University, he had written his first complete science fiction story and went to the New York offices of the Astounding Science Fiction magazine to meet the editor and submit it for publication. The Editor John Campbell, who is credited with having found and nurtured an entire generation of science fiction writers, and went on to become Asimovs trusted friend and editor for many years to come rejected the piece, with a cordial letter that explained to the young Asimov why the story didnt work and how he could get better. It would take nine more rejections before Asimov was finally published in another magazine called Amazing Stories.

For a writer so dedicated to his craft and one who wrote as much as he did, it took Asimov another twenty years to be able to earn enough to live off writing full time. In the meanwhile, he finished his Bachelor of Science degree, spent three years as a civilian chemist in World War II in Philadelphia, returned to New York and earned his doctorate in chemistry, and got a job as professor of biochemistry in Boston.

Till then and after, he wrote some of science fictions best loved stories. Stories of 200 year old robots who wanted to be human (The Bicentennial Man); of elections in an age where computers could predict the mood of the nation with a sample size of one (Franchise); of super computers who had all the knowledge of the world, and couldnt yet answer one important question (The Last Question), and a history of a future in which a great civilisation came to an end (Foundation)

But he was more than just a teller of made up stories. He was really invested in the science he wrote about, and the great pains he took to keep the science realistic in his stories is matched only by the pleasure he took in the research of it all. The simple evidence of how deeply he cared about the science of his stories is in the number of nonfiction books he wrote. He was as proud of being a science writer as he was of being a science fiction writer. Having written on subjects as varied as nuclear physics and human biology; Asimov the polymath is the poster child of multi-disciplinarity and academia as at ease in the hard sciences as in sociology and history; as eager to learn and read when he became a full professor as he was as a teenager; and able to write in a clear and concise manner in fiction and science.

An atheist all his life, Asimov was a member of the humanist movement, and believed that human beings are responsible for the progressive advancement of society, and must step up and alleviate the ills of society themselves, instead of depending on supernatural forces. He even went so far as to sign the Humanist Manifesto in 1970. His two volume Asimovs Guide to the Bible is also written from a strictly humanist point of view.

It is a vision reflected in his stories, in his hopes for possible futures. In 1984 35 years after George Orwells grim book of that name was published Asimov was asked by the Toronto Star to predict what the world might look like 35 years from then (in 2019), and he managed to get quite a bit right. Even though we havent come to a point where we can live under the faint semblance of a world government by co-operation and we havent shifted polluting industries in a wholesale manner to space; he did foresee the human races increasing reliance on computers and predicted that mobile computerised objects would penetrate the home. He also predicted that there would have to be a vast change in the nature of education because wed have to learn to live in an increasingly high tech world.

Asimov, above all, was an optimist someone who was sure that the inherent good in enough members of the human race would outrun the evil forces and keep humans going for millennia to come. Oh the robots we would build! And the galaxies we would colonise! What adventures we would have! It is a world view that recognises the challenges of war and natural disasters and discrimination; but it is filled with hope for a better future, a fantastic future, a kinder future.

Isaac Asimov was possibly the most successful science fiction writer of his time.(Getty Images)

Little Known Facts About Isaac Asimov1. When Isaac Asimov was about two years old, 17 children in his village, including Isaac, contracted double pneumonia a disease in which both lungs become inflamed, making it near impossible to breathe. All but Isaac died. He credits his survival to his mother, who after the doctor had given up on him, held baby Isaac in her arms without ever letting go until he was better.

2. Though he wrote extensively about interstellar travel, Asimov was afraid of flying, and almost never took flights.

3. Asimov was fond of music and thought of Tchaikovsky as music that makes me feel happy and Beethoven as music that makes me feel awed.

4. He wrote more than science and science fiction! Asimovs Guide To The Bible was written in two volumes in 1968 and 1969. And in 1970, he wrote Asimovs Guide To Shakespeare. He organised the plays not as tragedies, comedies, and histories (as is usually done) but by region Greek, Roman, Italian, English. Other than writing his autobiographies, Asimovs Guide To Shakespeare was according to him the most pleasant work Ive ever done.

5. Paul McCartney, in 1974, asked Asimov if he would write a screenplay for a science fictional movie musical about a band whose members were being impersonated by aliens. Asimov wrote it, but it was never made (speculation is that it had been rejected because Asimov neglected to use the scraps of dialogue that McCartney had suggested).

6. Apart from his own (what he called legitimate) PhD, Asimov was awarded 14 honorary doctorates in his lifetime.

7. When Asimov had a triple bypass surgery in 1983, he contracted HIV from a bad blood transfusion. In 1990, Asimov and his wife Janet Jeppson Asimov found out about it but they did not go public with this information on the advice of his doctors. It was not revealed even when he died in 1992 of heart and kidney failure caused by AIDS. The truth came to light in 2002, when Janet revealed it in the epilogue to Its Been A Good Life.

8. In September 1983, Asimov met Indira Gandhi, when she was in New York City to attend the UN General Assembly. She was a gracious and intelligent woman, he wrote about the meeting.

9. A fan of Sherlock Holmes, Asimov was a member of the official fan club The Baker Street Irregulars; and even wrote a song (to be sung to the tune of Danny Boy) in praise of the detective for an annual dinner of the club. The first few lines were: Oh, Sherlock Holmes, the Baker Street Irregulars/ Are Gathered here to honour you today,/ For in their hearts you glitter like a thousand stars,/And like the stars, youll never fade away.

The Laws Of RoboticsOne of Asimovs most memorable contributions to the world are his Three Laws of Robotics. While scientists and others have written their own laws since, Asimovs were the first, most popular, and remain at the heart of all other laws of robotics. They have also formed the bedrock of much of sci-fi involving robots. Many writers have written stories, simply assuming the laws as fact.The Laws as Asimov wrote them:1. A robot may not injure a human being or, through inaction, allow a human being to come to harm.

2. A robot must obey the orders given it by human beings except where such orders would conflict with the first law.

3. A robot must protect its own existence as long as such protection does not conflict with the first or second laws.

Asimov credits his friend and publisher John Campbell with having come up with them.

It was at a meeting between Asimov and Campbell where Campbell was actually rejecting one of Asimovs stories that the idea for the laws emerged. Asimov was pitching a story about a robot that had become capable of reading minds due to a minor mistake on the assembly line.

And as they talked of the complications that robot telepathy might present, Campbell said, Look, Asimov, in working this out, you have to realize that there are three rules that robots have to follow. In the first place, they cant do any harm to human beings; in the second place, they have to obey orders without doing harm; in the third, they have to protect themselves, without doing harm or proving disobedient. Well ...

The Writers Personal FavouritesIn 1968, Asimovs story Nightfall was voted the best science fiction short story ever written, by the Science Fiction Writers of America, and many think that honour still holds.

But what were Asimovs favourites from among his own work?

Helpfully, he has answered the question himself. His own three favourite short stories were, in descending order:

(1) The Last Question

(2) The Bicentennial Man

(3) The Ugly Little Boy

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To the stars and beyond: A hundred years of Isaac Asimov - Hindustan Times

How Inflammation Can Lead to Depression – Psychology Today

When we think of things like depression, the role of inflammation seems secondary to, perhaps, social circumstances that cause sadness and trauma, or even ourgenetics, which is a continuous field of study in mental health. Inflammation in brain and spinal cord tissue (also known as headaches and backaches) can usually be lessened by swallowing a Tylenol or two. But researchers in Georgia and South Carolina were recently awarded grants from the National Institute of Mental Health (NIMH) to study the biochemistry that contributes to inflammation.

"Everything has a price. The price, however, isn't always money." -Ahmed Mostafa

Source: Wikimedia Commons

Why?

It goes back to swallowing a Tylenol to make your pain dissipatein other words, your biochemistry. In order to better understand our biochemistry and why Tylenol and other drugs are effective, we have to understand something called the complement system or the complement cascade. The complement system is part of a humans immune system.

Our immune system provides checks and balances throughout the body to keep us healthy. The complement system is made up of proteins derived from the liver. If your liver isnt healthy, theres a good chance you may be unhealthy in other areas as wellincluding your mental health.

The complement system was named by Paul Ehrlich (1854-1915). Ehrlich won a Nobel Prize for his contributions in immunology; he discovered the cure for syphilis, and in so doing, coined the term chemotherapy. Chemotherapy basically means using chemistry to treat diseasethough today, people use the phrase almost exclusively for the treatment of cancer.

When a human gets an infectionwhich can include something like the common cold orfluone of the first responses by the immune system is inflammation. Inflammation is a physical barrier, meant to help contain the infection in order to help promote healing. But researchers at the Medical College of Georgia at Augusta University have found that chronic stress actually causes inflammation in the brainin the same way that cold germs cause inflammation in our throat and nasal passages. Inflammation of the brain essentially destroys the connections between neurons, causing depression.

Monocytes are white blood cells.Monocytes circulate throughout our bodies during periods of stress as a line of defense. But it is the microglia or the immune cells in the brainthat may be delivering excess C3, a small protein from the complement system that causes continuous inflammation in the brain, which then contributes to depression.

Researchers at the Medical University of South Carolina College of Medicine are collaborating with Georgia researchers because their lab synthesizes something called complement inhibitors, or drugs that block C3 activation.

Though interferon-alpha is a drug used to treat cancer, its also a naturally-occurring protein produced by our bodies to stimulate the immune system in order to stop viral infections and the development of melanoma (skin cancer)a very useful aspect to our biochemistry. The problem comes in with prolonged use of the synthesized version. Patients treated with interferon-alpha for long periods of time had depression and other mental health issues.[i] Its interesting to note that when overused as a synthesized drug, the very protein our bodies create on their own works against us.

The theory is that increases in interferon-alphawhether through chronic stress or something like the treatment of canceractivatethe microglia, the immune cells in the brain. Activating the microglia ups the production of the C3 protein, which in turn not only damages communication between our neurons but outright destroys the connections between them. When our neurons cant communicate, we dont think properly. When we cant think properly, we cant act properly.

As we move into 2020, its important to remember that keeping ourselves in stressful environmentswhether at home or through a jobis not just causing situational depression (or temporary depression that goes away when the difficulty does), it mayactually be destroying brain function. The more we understand about how our bodies work, the healthier our minds will be, too.

In the new year, its of the utmost importance to remove yourself from anyrelationship that is causing chronic stress. Think of people who abuse you as not just abusers you can walk away from, but individuals who are causing you, your body, and your mind irreparable harm that can and will permanently affect both your physical and mental health.

No person or situation is worth injuring your life. Start fresh in 2020. If you have a difficult relationship, begin regular counseling sessions so you can at least have less stress as you work toward financial independence, increasing your ability to leave the toxicity behind. If your partner isnt amenable to counseling, you can always go to talk therapy sessions on your own.

Protecting your brain from the effects of chronic stress protects every aspect of your life. The year 2020 is all about living longer and stronger. That starts the moment you begin believing in yourself.

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How Inflammation Can Lead to Depression - Psychology Today

Biochemistry | Smith College

Because biochemistry builds on the fundamentals of both biology and chemistry, students who major in biochemistry begin by taking introductory courses in both of these fields. Biochemistry follows in either your second or third year, along with additional courses in cell biology, physiology, molecular biology and physical chemistry. More specialized courses can be selected according to students' individual interests.

*Exemption from BIO 132/133 may be obtained if you received advanced placement on your Smith College transcript for biology (e.g. AP, International Baccalaureate, A levels).

Note: An equivalent sequence would beCHM 118 (Advanced General Chemistry), CHM 222 (Chemistry II: Organic Chemistry) and CHM 223 (Chemistry III: Organic Chemistry)

*If you received advanced placement on your Smith College transcript for chemistry, you are strongly encouraged to start the introductory chemistry courses with CHM 118.

Choose one:

Choose one:

The S/U grading option is not allowed for courses counting toward the biochemistry major.

You are advised to complete all the following foundational courses before your junior year: BIO 132/133, 202/203, CHM 111, 222, 223, and 224 or 118, 222, and 223, BCH 252/253.

Majors are encouraged to include research in the form of a special studies (BCH 400, 400D) or honors project (BCH 430D, 432D) in their course of study.

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Biochemistry | Smith College

UNL students give their thoughts on impeachment hearings – Daily Nebraskan

Impeachment hearings are underway on Capitol Hill as the U.S. House of Representatives Permanent Select Committee on Intelligence works to decide if there will be an impeachment trial for President Donald Trump. The Daily Nebraskan asked students if they have been paying attention to the hearings and if they think impeachment is likely.

Pierce Leef, sophomore biochemistry and science education double major

Pierce Leef, sophomore biochemistry and science education double major

I havent been really paying attention. Ive wanted to, but theres a lot of other stuff going on right now, and its really busy. I personally hope that there is something involved with at least the process of going through and seeing what actually has happened and what hasnt because theres been a lot of misinformation on both sides. Just figuring out the real truth would be good.

Cleopatra Babor, freshman plant biology major

Cleopatra Babor, freshman plant biology major

I have been paying attention, and I believe that impeachment is very unlikely. Just all the information [President Trump] has been hiding is probably the most shocking thing, but in my personal opinion, we kind of all already knew [he was hiding information]. Its very close to the 2020 election and thats why I think impeachment is pushing to the unlikely side. But theres still hope.

Louis Lu, junior actuarial science major

Louis Lu, junior actuarial science

I havent been paying attention. For me, I am not really sure about politics in America because I dont really care about that because Im a Chinese student. Maybe [impeachment] is possible.

Alex Bartels, junior advertising and public relations major

Alex Bartels, junior advertising and public relations major

I have not been paying attention to the impeachment hearings. I just dont really pay attention to politics and dont really follow anyone on social media that talks about politics. I dont know much about it and also just dont really know if [impeachment] is possible or not. I feel like they probably wont impeach since the election is already coming up next year.

Ali Mohamed, junior education major

Ali Mohamed, junior education major

Ive seen clips here and there, but I havent been really paying attention. [Impeachment] is probably not going to happen. Its been going on for a while, and I feel like theyre dragging it on. By that time, hes probably going to be out of the office.

news@dailynebraskan.com

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UNL students give their thoughts on impeachment hearings - Daily Nebraskan

Holiday depression: Causes and treatment options – WUTR/WFXV – CNYhomepage.com

Holiday depression, or seasonal affective disorder, tends to occur when the season changes from summer to fall. For some people its their bodys response to the change in weather and lack of sunlight, thus altering their overall mood. Others are directly affected by the stress or lonliness during the holiday season.

Stress associated with trying to make, or meet all of those demands that are sometimes placed on us and those types of things. So clinical would be somethings actually affecting the biochemistry of the body and situational happens to be that situation thats going on. And then for some of us you know, snow, the weathers bad, getting out of the house isnt as easy, its probably easier to stay home. So we feel like were caged in and were kind of stuck. And that takes, and also has an impact on people. Jim Davis, Executive Director, Samaritan Counseling Center

Treatment options can vary depending on the patients goals and personal needs.

It could be a combination of individual counseling and family counseling, or individual counseling with couples depending on the needs of the people that were working with. Jim Davis, Executive Director, Samaritan Counseling Center

An important part of battling any type of depression is to stay connected with people and engage in activities. Whether its exercising, taking on a new hobby or surrounding yourself with loved ones. If you or someone you know is coping with depression, please contact the National Suicide Prevention Hotline at 1-800-273-8255.

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Holiday depression: Causes and treatment options - WUTR/WFXV - CNYhomepage.com

Biochemist Peter Hinkle dies at 76 – Cornell Chronicle

Peter C. Hinkle, Cornell professor emeritus of biochemistry, cell and molecular biology, died May 12 in Ithaca of pancreatic cancer. He was 76.

Widely acknowledged as a brilliant biochemist, Hinkle was an early adopter of a groundbreaking new approach to understanding the energy metabolism in cells. Though originally trained in classical biochemistry, Hinkle chose to do postdoctoral work in England with Peter Mitchell, who had postulated a new approach to how cells acquire the carbon and energy they need to grow, the chemiosmotic theory, for which Mitchell received the Nobel Prize in 1978.

The chemiosmotic mechanism postulated by Mitchell was not easily understood by those trained in classical biochemistry, but Peter Hinkle did understand and brought those ideas to Cornell where they took root, said Joseph Calvo, professor emeritus of molecular biology and genetics.

Hinkle received a bachelor's degree in biochemistry from Harvard University in 1962 and a doctorate from New York University in 1967. His work with Mitchell at Glynn Research was supported by a National Institutes of Health fellowship. His scientific promise was also recognized early by a 1971 NIH Career Development Award.

After his work at Glynn, Hinkle came to Cornell as a postdoctoral fellow in 1969. He became an assistant professor in 1973, part of a cohort of new faculty hired to strengthen biology across the campus.

Peter was a valued member of our department for 44 years, said William Brown, professor and chair of the Department of Molecular Biology and Genetics in the College of Arts and Sciences. He was at the forefront of elucidating how cells make ATP, the energy currency of life on this planet.

Hinkle and others, including Efraim Racker, Andre Jagendorf and Richard McCarty, provided convincing experimental evidence for the chemiosmotic theory.

Peter Hinkle made a number of very important contributions to the required paradigm shift, said Calvo. He was an exacting experimentalist who had a highly developed understanding of laboratory conditions that avoided artifacts. He was asked to review many research papers and invited to meetings throughout the developed world.

One of Hinkles most important contributions was to frame the chemiosmotic theory in a way that could be understood by the greater scientific community. He published, with McCarty, a seminal article in Scientific American that included state-of-the-art drawings of ATP synthesis in plant and animal cells, emphasizing the basic similarities in the two cases. Hinkles wife, Maija, played a major role in developing the drawings. Some version of those drawings is in every biochemistry text sold today, said Calvo.

Peter and his colleagues also made very important contributions toward the understanding of how molecules cross biological membranes, said McCarty, the W.D. Gill Professor Emeritus of Biology at John Hopkins University. His lab was the first to show that the membranes of animal cells contain an embedded protein that mediates the transport of glucose across the membranes.

Hinkle became a full professor at Cornell in 1983 and served as chair of what was then known as the Department of Biochemistry, Molecular and Cell Biology from 1985 to 1988. He taught, said Brown, legions of students in his graduate courses in bioenergetics and undergraduate courses in biochemistry, as well as his course Ethical Issues and Professional Responsibilities. In 2003, he and senior lecturer Jim Blankenship received a Faculty Innovation in Teaching grant to add web-based activities that incorporated 3-D visualization of proteins as well as interactive animations to the auto-tutorial course, Biochemistry 330.

During 1988-89 Hinkle served as distinguished visiting scientist at the Roche Institute of Molecular Biology in New Jersey. He served on numerous editorial boards, most recently for the Journal of Bioenergetics and Biomembranes.

After his retirement in 2014, Hinkle pursued interests including electronic music; he incorporated bird songs into his compositions.

Hinkle is survived by his widow, three sons, four granddaughters and two brothers.

A celebration of Hinkles life will take place Saturday, May 20, at 11 a.m. in the Founders Room in Anabel Taylor Hall. In lieu of flowers, memorial donations can be made to the Cornell Lab of Ornithology or to the Norwood and Cornelia Scholarship Fund at The Putney School.

Linda B. Glaser is a staff writer for the College of Arts and Sciences.

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Biochemist Peter Hinkle dies at 76 - Cornell Chronicle

Biochemistry (B.S.) | Degree Programs | Clemson University …

One of the first courses biochemistry majors are required to take is designed to introduce you to careers, professional organizations, ethical issues and the requirements for advanced studies. In the first two years, youll take various courses in the sciences such as general, organic, quantitative and physical chemistry as well as physics and biology. Each of these courses builds a foundation for you to be successful in the upper-level course work in biochemistry, metabolism, cell biology and bioinformatics. Additionally, you can tailor your degree to your specific career goals as you choose your upper-level science classes. Pick from approved science requirements such as human anatomy and physiology, plant pathology, genetics, microbiology, pathogenic bacteriology and immunology.

Because biochemistry spills over into pharmacology, physiology, microbiology and clinical chemistry, a bachelors degree in biochemistry can offer a direct path to a career in government or industry. The U.S. Department of Agriculture, the National Institutes of Health and the Environmental Protection Agency are just a few of the government agencies that employ biochemists specializing in basic research. The pharmaceutical and biotechnology industries employ biochemists in research as well as in areas outside the lab such as marketing, management, science information, technical writing and editing. This degree is also a great foundation for professional programs such as medical, dental, veterinary and even law.

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Biochemistry (B.S.) | Degree Programs | Clemson University ...

Vacancies at AIIMS, Jodhpur for 48 Junior Resident and Tutor/Demonstrator (Biochemistry) Posts – Jagran Josh

All India Institute of Medical Sciences, Jodhpur Jobs Notification: All India Institute of Medical Sciences, Jodhpur invited applications for the post of Junior Resident (Clinical) and Tutor/Demonstrator (Biochemistry) Posts. The eligible candidates can apply to the post through the prescribed format and walk in interview on 28 March 2017.

Junior Resident (Clinical) candidates must possess MBBS from the MCI recognized Institute. The Candidate must have compulsory rotatory internship and must produce internship completion certificate

Tutor/Demonstrator (Biochemistry) candidates must possess MBBS from the MCI recognized Institute or M.Sc. in Biochemistry. The Candidate must have compulsory rotatory internship and must produce internship completion certificate for MBBS Candidates

Eligible candidates can apply to the post through the prescribed format and walk in interview on 28 March 2017at 10:00am at Medical College of AIIMS, Jodhpur (Rajasthan).

Official Notification

Vacancy Summary

Notification details

Notification No. :Admn/Estt/01/JR/2017-AIIMS.JDH

Important Date:

Walk in interview - 28 March 2017 at 10:00

Age Limit Junior Resident (Clinical) and Tutor/Demonstrator (Biochemistry) Posts- 30 Years

Selection Procedure forJunior Resident (Clinical) and Tutor/Demonstrator (Biochemistry) PostsJob

The selection will be on the basis of the interview. The list of selected candidates will be uploaded on website. Candidates are advised to check the Institute website regularly for information

Application Fees for Junior Resident (Clinical) and Tutor/Demonstrator (Biochemistry) Posts

Gen & OBC : Rs.1000/-

SC/ST: NIL

Women Candidates: NIL

Official Website

http://www.aiimsjodhpur.edu.in

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Vacancies at AIIMS, Jodhpur for 48 Junior Resident and Tutor/Demonstrator (Biochemistry) Posts - Jagran Josh

Seniors Present Science Theses – Middlebury Campus (subscription)

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Julie Merchant 17 presents on the role of vesicle pH in neurotransmitter transport.

Julie Merchant 17 presents on the role of vesicle pH in neurotransmitter transport.

Sabina Haque, Contributing Writer May 10, 2017 Filed under Arts & Sciences

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As the 201617 academic year slowly draws to a close, McCardell Bicentennial Hall remains abuzz with activity, as senior thesis presentations are in full swing. Many soon-to-be graduates of the biology, neuroscience, chemistry & biochemistry, molecular biology & biochemistry and conservation biology departments have spent the greater part of the past year in the lab or the field, working diligently to produce independent research with various professors at the College.

While the chemistry & biochemistry department indulges its devoted students in three to four hour-long sessions on Friday afternoons (an extravaganza more fulfilling than binge-watching The Office), the biology-focused departments prefer to sprinkle their presentations across the lunch hour throughout the past week. For this issue, three particular student presentations are featured: Eric Stanton, Julie Merchant and Laura Bashor.

Eric Stanton 17, a biochemistry major working in Professor Jeff Byerss lab, presented his work entitled Synthesis of a Chromium Complexed Poly-(p-phenylene ethynylene) Polymer as a Potential Molecular Wire on Friday, May 5. Using the organic synthesis techniques characteristic of the Byers lab, he described the steps taken that enabled him to construct a complexed p-phenylene ethnylene (PPE) polymer starting from dichlorobenzene.

Stanton then moved into the results of his work. When he assayed the stability of his synthetic polymer with NMR, a common chemical laboratory technique, he was surprised to see that his complex was not as stable as expected. Stanton then performed fluorescent quenching, which involves exposing polymers to UV light and measuring the excited state charge transfer. While Stantons polymer did not display the stability that he had hoped, he found that fluorescent quenching provided a better model to understand this complex.

On Monday, May 8, Julie Merchant 17 and Laura Bashor 17 both presented during the lunch hour, representing the biology department. After a jovial and entertaining introduction from her advisor Professor Glen Ernstrom, Merchant kicked off the session with her dynamic presentation of Optogenetic acidification of synaptic vesicles in C. elegans. She explored how neurons communicate, which led naturally into a brief but thorough review of neurotransmission and a helpful analogy connecting neuronal communication to a water balloon fight.

Merchants research focuses on understanding the importance of vesicle pH in regulating the transport of neurotransmitters into synaptic vesicles. When these synaptic vesicles are only partially filled, they are less likely to fuse with target cells into which the neurotransmitters are meant to be delivered. This results in pronounced behavioral defects such as deficits in motor coordinates and balance.

Her hypothesis was that the acidification provides a molecular checkpoint that instructs vesicles to fuse properly. Through a variety of experiments, she was able to demonstrate that a proton pump-deficient C. elegans mutant has diminished vesicle fusion. Merchant was also able to restore an acidification-related defect in said C. elegans mutant by expressing a protein on the vesicle surface that acidifies the vesicle in response to light stimulus.

In a brief introduction, Allen mentioned that Bashor would soon be presenting her work to the Ecological Society of America. Bashors thesis project, Lyme disease and elevation: a dynamic ecological relationship, focused on work she had been pursuing in Professor David Allens laboratory since the summer. She opened with an array of statistics depicting the stark increase of Lyme disease cases in the United States, and particularly Vermont. In an effort to untangle the ecology of Lyme disease, Bashor addressed the fact that although the black legged tick is the most infamous of Lyme disease carriers, other small mammals could actually be implicated as the biggest contributors to human infection.

At the heart of Bashors work was the connection between elevation and Lyme disease risk, as the life cycles of the black legged tick and various small mammals are in turn determined by such environmental factors. Along an elevational gradient, Bashor collected ticks, the white footed mouse and deer mouse and tried to identify elevations effect on the distribution of Lyme disease infection rates. She found in her samples that, although the white-footed mouse is thought of as a more common vector for Lyme disease, the deer mouse actually was infected with Lyme disease at a much higher rate. In addition, she observed differences in the activity and densities of the black legged tick along an elevational gradient, implicating that the ecology of Lyme disease is tied inherently to elevation.

While these three presentations represent only a small subset of the talks that have been given over the past few weeks, they provide a brief glance at the diligent work that happens behind closed lab doors.

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Seniors Present Science Theses - Middlebury Campus (subscription)

Global Biochemistry Analyzers Market is Estimated to be Valued at US$ 4625.3 Million by 2024 – MilTech

The clinical use of biochemistry analyzers in measurement solutions such as latex agglutination, ion-selective potentiometry, and colorimetric & photometric testing. In addition to this, accuracy of biochemistry analyzers in analyzing blood and urine samples has benefited pathology labs and diagnostic centers across the globe. Persistence Market Research predicts that the global demand for biochemistry analyzers will continue to soar on the grounds of such factors. A recent report published by Persistence Market Research projects that by the end of 2024, the global market for biochemistry analyzers will reach US$ 4,625.3 Mn in terms of value.

Key findings in the report cite that the use of chemistry analyzers spans from high-throughput clinical labs to point-of-care clinics, and its use for testing enzymes, electrolytes and proteins is gaining traction. The report current values the global biochemistry analyzer market at a little over US$ 3,000 Mn. During the forecast period, revenues generated through global sales of biochemistry analyzers are, thus, expected to soar at a steady CAGR of 5.5%.

Key Research Insights from the Report include:

Roche Diagnostics GmbH, Siemens AG, Beckman Coulter Inc., Abbott Diagnostics Inc., Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Hologic, Inc., Randox Laboratories, Ltd., Awareness Technology, Inc., Transasia Biomedicals Ltd., and Nova Biomedical Corp. are profiled in the report as key players of global biochemistry analyzer market.

A Sample of this Report is Available Upon Request @ http://www.persistencemarketresearch.com/samples/6451

The report further reveals that fully-automated biochemistry analyzers will remain in great demand in the years to come. In 2017 and beyond, more than 85% of global biochemistry analyzer revenues will be accounted by sales of fully-automated biochemistry analyzers. Moreover, clinical diagnostics will also remain the largest application of biochemistry analyzers throughout the forecast period. Revenues accounted by global sales of biochemistry analyzers in clinical diagnostics are anticipated to register speedy growth at 5.7% CAGR. The report further identifies diagnostic centers as largest end-users of biochemistry analyzers in the world. On the other hand, rising number of point-of-care diagnostic labs instated in hospitals will render a key end-user of biochemistry analyzers. Together, hospitals and diagnostics centers will be responsible for procure over two-third of global biochemistry analyzers revenues through 2024.

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The use of biochemistry analyzers in drug development applications is also expected to gain traction in the future. Based on modality, the report forecasts that in 2016, more than 70% of the market value was accounted by bench-top biochemistry analyzers. However, towards the end of the forecast period, the demand for bench-top modality will incur a marginal decline, while floor standing biochemistry analyzers will bring in over US$ 1,200 Mn revenues.

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Global Biochemistry Analyzers Market is Estimated to be Valued at US$ 4625.3 Million by 2024 - MilTech

Historically Speaking: Fred Snyder Blood lipid mediators and cancer research at ORAU – Oak Ridger

As often happens when the weekly Historically Speaking is published, my phone begins to ring with people who have ideas for additional stories based on the one just released. Such was the case with Dr. Fred Snyder. His call was to suggest another scientific program at Oak Ridge Associated Universities. It was a large basic lipid research program running from 1958 to 1995.

As often happens when the weekly Historically Speaking is published, my phone begins to ring with people who have ideas for additional stories based on the one just released. Such was the case with Dr. Fred Snyder. His call was to suggest another scientific program at Oak Ridge Associated Universities. It was a large basic lipid research program running from 1958 to 1995.

My first call was to Pam Bonee of ORAU to see what information was available on such a program. She provided several press releases and other information about the program Fred had called me about.

An interesting aspect of this research is that it is not a mainstream type of research activity one would expect to find at a Department of Energy facility. Yet, the early years of such programs encouraged by the Atomic Energy Commission and later DOE in medical related research was important to basic scientific discovery and excelled in bringing new technology to bear on serious and difficult problems.

First, lets get to know Fred Snyder before he came to ORAU. He was born in New Ulm, Minn., an 1854 settlement of German immigrants. The name, New Ulm, was selected because many of the original settlers were from the Province of Wurttemberg, Germany, of which Ulm is the principal city.

How Fred got his name is a bit unusual. His uncle, also named Fred, bribed Freds parents by offering to buy them a baby crib if they named their baby after him so Fred Leonard Snyder was born.

Fred grew up in Wabasso, Minn., about an hour from New Ulm. Wabasso was a small community of some 600 people, so Freds high school graduation class had 31 students.

After graduation, Fred attended St. Cloud State University, earning a Bachelor of Science degree. During his senior year, a course in physiological chemistry fascinated him and persuaded him to look into graduate programs in this field.

This led him to the University of North Dakota. A discussion with Dr. W.E. Cornatzer, a professor and head of a newly formed Department of Biochemistry at the Medical School of the University of North Dakota had increased his interest in biochemistry.

Fred obtained a Master of Science degree in Biochemistry and decided to pursue the Ph.D. in Biochemistry. He already had a keen interest in lipids because that was the primary research interest of Dr. Cornatzer, who was having a significant influence on Fred at the time and continued to mentor him.

Fred focused on a singular primary path throughout his education and career lipids. Yet, he has had a broad scientific impact and has served to help many others progress in their careers.

Fred was awarded a Pre-Doctoral Fellowship from the National Heart Institute, which would have allowed him to study at the school of his choice. For several reasons, including family considerations and Dr. Cornatzers new program there, he chose to continue his studies at the University of North Dakota. This university has awarded him two additional honorary degrees over the years.

With a Ph.D. in Biochemistry from the University of North Dakota,in 1958, right out of school and ready for his very first real job, Freds professor advisor, Dr. Cornatzer, knew Dr. Granvil Kyker who worked at ORAU and made the connection for him.

Dr. Kyker was busy doing work on rare earth metals associated with uranium. One of the results of injecting these metals into rats was that they developed fatty livers. He was looking for a Ph.D biochemist trained in the area of lipid metabolism to help understand why this was happening.

Lipids are a fatty substance in the blood that are involved in many body processes and were thought to possibly be a key to furthering this research on fatty livers. It was a perfect fit for Fred. He proudly tells about his excitement with his job at ORAU over the years and with equal pride will tell you that he worked for ORAU his entire career.

Upon his arrival at ORAUs Medical Division, Fred was impressed with the freedom he was given regarding his continuing lipid-related research. He said, This one and only job for me was like a hobby since I was able to seek funding from the National Institutes of Health and the American Cancer Society and hire the doctoral and graduate students to help successfully accomplish the goals we developed for our research pursuits.

Additionally, he was asked to serve as an adjunct professor at the University of North Carolina and the University of Tennessee. This also provided the opportunity to bring graduate students to ORAU, seven of whom earned their Ph.D.s while working there. There were also 23 postdoctoral fellows who worked for Fred for one to two years coming from coming from France, Egypt, Netherlands, Japan, China, New Zealand, Poland and the United States.

Grants from the American Cancer Society and the National Heart, Lung and Blood Institute were typical of funding sources. The biochemistry program received approximately $29 million in grants and DOE funding over the years. Fred has the distinction of holding the longest running American Cancer Society grant at the time of his retirement.

From 1988 to retirement in 1995, Fred was an ORAU Corporate Distinguished Scientist. He served on 15 editorial boards ranging from cancer research to biochemistry and biophysics. He was awarded an honorary Doctor of Science degree from the University of North Dakota in 1983.

During those 37 years at ORAU, he and his staff created an internationally known biochemistry program that made several significant contributions in cancer research. One of the more significant ones was the discovery of the platelet-activating factor (PAF) a mediator involved in allergies and blood pressure control.

An ORAU press release stated, PAF plays a major role in inflammation, and various physiological areas such as reproduction and blood pressure control. At the time, certain drug manufacturers carried out research to test synthetic compounds for anti-inflammatory and tumor-reducing capabilities based on the structure and function of PAF.

The release continued, In the late 1960s, the discovery that ether lipids (fatty substances) are more common in cancer cells also marked a significant accomplishment of Snyder and his co-workers. They then learned how cells make these lipids, which provided important information used my numerous other groups in investigating the role of lipids and membranes in cancer.

The highly successful biochemistry program also resulted in annual international conferences being held. One of them was held in Gatlinburg, because of the prestige of the ORAU program and another was held in honor of Freds 60th birthday. The conference was titled, The Fred Snyder Conference on Structure Function, & Dynamics of Lipids.

Fred was world renowned for his expertise and was often chosen to speak at other international conferences allowing him to travel extensively to many parts of the world. The speaking engagement were so many that he says one such series of conference appointments enabled him to literally travel around the world.

During his distinguished career, he published more than 350 journal articles, served as editor on four books and presented many invited lectures at both national and international conferences.

Fred retired, after 37 years, in 1995 as vice chairman of the Medical Sciences Division of the Oak Ridge Institute for Science and Education, as well as the director of the divisions Biochemistry Program. He was one of two ORAU Corporate Distinguished Scientists during his career. The other one was Alvin Weinberg.

There you have yet another example of an interesting and unique career in Oak Ridge. Fred reminded us of the many and varied opportunities that can come with the type of careers available here in Oak Ridge.

His travels to medical meetings and conferences all over the world, the people with whom he interacted, many of whom he continues to remain in touch through email even today, and the other workers who gained experience because of the biochemistry program at ORAU, all resulted because of one mans interest in a specialized career field of biochemistry. And dont forget the encouragement Fred received from his mentor, Dr. W.E. Cornatzer.

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Historically Speaking: Fred Snyder Blood lipid mediators and cancer research at ORAU - Oak Ridger

Research spotlights early signs of disease using infrared light: New research – Science Daily

Research spotlights early signs of disease using infrared light: New research
Science Daily
Produced from the cell membranes of mammals, microvesicles play a role in cell communication and carry a "cargo" of RNA, DNA, proteins, lipids and other biomolecules that they use to dramatically change the biochemistry of other cells. Microvesicles ...

and more »

Original post:
Research spotlights early signs of disease using infrared light: New research - Science Daily

New Jersey Health Foundation grants advance research – Rowan Today

Ghulam Rasool envisions an improved bionic arm and hand that is more functional and affordable than those already on the market.

Now, Rasools evolving research is getting a boost.

Rasool, an assistant professor of Electrical and Computer Engineering, is one of seven Rowan faculty members who recently received funding from the New Jersey Health Foundation for health-related research. Nearly 23 percent of the foundations latest grants were awarded to Rowan faculty.

The Princeton-based nonprofit supports faculty and student researchers at New Jersey-based organizations with financial resources. The grants help researchers move their projects out of the lab and into the real world, said Beena Sukumaran, vice president for research at Rowan.

Theyre taking their research and applying it to real life, she said.

Rasools project would create a prosthetic limb that combines neuroscience with practicality.

The user would be able to control the wrist joint and finger of the hand by just thinking about what theyre trying to do, Rasool said. The idea is that when someone gets an amputation, the limb may be lost. However, the neurons that connect the brain to the limb may still be there.

What we can do is tap into those neurons and get access to the electrical signals coming from the brain to muscles. We can use these electrical signals and learn about the movement the person was trying to perform or was just thinking about.

This is the second consecutive year Rasool has received a $35,000 grant from the foundation for his research.

In the first year of Rasools project, known as EnaBLe (for enhanced bionic limb), he and his student researchers built prototypes of the bionic arm. This year, they hope to discover how the bionic arm can mimic human movements in the non-amputee population. In 2021, Rasool and the students will begin working with forearm amputees to test the device.

Grant funding is vital, Rasool said.

Working with students, their stipends, equipment and lab space, all of these things require continued financial support, Rasool said.

Without these grants, awards and financial support for research, Rasool added, we wouldnt be able to make progress.

In addition to Rasool, the following faculty received grants from the foundation:

Originally posted here:
New Jersey Health Foundation grants advance research - Rowan Today

Automated Biochemistry Analyzers Market Top key Players, Size, Share, Demand, Opportunities And Forecasts To 2025 – Surfacing Magazine

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Table of Contents1. Executive Summary2. Assumptions and Acronyms Used3. Research Methodology4. Market Overview5. Global Market Analysis and Forecast, by Types6. Global Market Analysis and Forecast, by Applications7. Global Market Analysis and Forecast, by Regions8. North America Market Analysis and Forecast9. Latin America Market Analysis and Forecast10. Europe Market Analysis and Forecast11. Asia Pacific Market Analysis and Forecast12. Middle East & Africa Market Analysis and Forecast13. Competition Landscape

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Automated Biochemistry Analyzers Market Top key Players, Size, Share, Demand, Opportunities And Forecasts To 2025 - Surfacing Magazine