Non-lethal Biochemical Weapons size and Key Trends in terms of volume and value 2019-2021 – News Times

Global Non-lethal Biochemical Weapons Market Report 2019 Market Size, Share, Price, Trend and Forecast is a professional and in-depth study on the current state of the global Non-lethal Biochemical Weapons industry.

The report also covers segment data, including: type segment, industry segment, channel segment etc. cover different segment market size, both volume and value. Also cover different industries clients information, which is very important for the manufacturers.

There are 4 key segments covered in this report: competitor segment, product type segment, end use/application segment and geography segment.

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For competitor segment, the report includes global key players of Non-lethal Biochemical Weapons as well as some small players.

companies profiled in this report are BAE Systems, Inc.; Lamperd Less Lethal, Inc., Taser International, Inc.; Raytheon Company; Textron Systems, Corp.; General Dynamics Corporation; Chemring Group PLC.; Moog, Inc; Qinetiq Group, Inc.; and LRAD Corporation. These organizations focus on evolving innovative products after investment of substantial amount of their net sales in research and development for introducing progressive technologies with large range abilities, reduced weight, and relatively higher precision.

The segments covered in the Non-Lethal Biochemical Weapons market are as follows:

Global Non-Lethal Biochemical Weapons Market: By Operation Type

Global Non-Lethal Biochemical Weapons Market: By Product Type

Global Non-Lethal Biochemical Weapons Market: By End Use

Global Non-Lethal Biochemical Weapons Market: By Geography

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Important Key questions answered in Non-lethal Biochemical Weapons market report:

What will the market growth rate, Overview, and Analysis by Type of Non-lethal Biochemical Weapons in 2024?

What are the key factors affecting market dynamics? What are the drivers, challenges, and business risks in Non-lethal Biochemical Weapons market?

What is Dynamics, This Overview Includes Analysis of Scope and price analysis of top Manufacturers Profiles?

Who Are Opportunities, Risk and Driving Force of Non-lethal Biochemical Weapons market? Knows Upstream Raw Materials Sourcing and Downstream Buyers.

Who are the key manufacturers in space? Business Overview by Type, Applications, Gross Margin, and Market Share

What are the opportunities and threats faced by manufacturers in the global market?

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The content of the study subjects, includes a total of 15 chapters:

Chapter 1, to describe Non-lethal Biochemical Weapons product scope, market overview, market opportunities, market driving force and market risks.

Chapter 2, to profile the top manufacturers of Non-lethal Biochemical Weapons , with price, sales, revenue and global market share of Non-lethal Biochemical Weapons in 2019 and 2015.

Chapter 3, the Non-lethal Biochemical Weapons competitive situation, sales, revenue and global market share of top manufacturers are analyzed emphatically by landscape contrast.

Chapter 4, the Non-lethal Biochemical Weapons breakdown data are shown at the regional level, to show the sales, revenue and growth by regions, from 2019 to 2025.

Chapter 5, 6, 7, 8 and 9, to break the sales data at the country level, with sales, revenue and market share for key countries in the world, from 2019 to 2025.

Chapter 10 and 11, to segment the sales by type and application, with sales market share and growth rate by type, application, from 2019 to 2025.

Chapter 12, Non-lethal Biochemical Weapons market forecast, by regions, type and application, with sales and revenue, from 2019 to 2025.

Chapter 13, 14 and 15, to describe Non-lethal Biochemical Weapons sales channel, distributors, customers, research findings and conclusion, appendix and data source.

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Non-lethal Biochemical Weapons size and Key Trends in terms of volume and value 2019-2021 - News Times

Dihydropyridine Market 2020 | Know the Latest COVID19 Impact Analysis And Strategies of Key Players: Shenzhen Simeiquan Biotechnology Co.Ltd, Boc…

Global Dihydropyridine Market report shows the Industry Chain Structure as well as Macroeconomic Environment Analysis and Development Trend. The Dihydropyridine Market report also provides the market impact and new opportunities created due to the COVID19/CORONA Virus catastrophe The total market is further divided by company, by country, and by application/types for the competitive landscape analysis. The report then estimates 2020-2025 market development trends of Dihydropyridine Industry.

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The Top players are Shenzhen Simeiquan Biotechnology Co.Ltd, Boc Sciences, Weifang Union Biochemistry Co.,Ltd, Angene International Limited, Triveni Chemicals, Yuyao Tuqiang Chemical Co., Ltd., Skyrun Industrial Co., Ltd., Neostar United Industrial Co., Ltd., Haihang Industry Co., Ltd..

Market Segmentation:

Dihydropyridine Market is analyzed by types like Purity:99%, Purity:98%, Other

On the basis of the end users/applications, Medicine, Chemical Intermediate, Other

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Global Dihydropyridine Market report describes the development of the industry by upstream and downstream, industry overall and development, key companies, as well as type segment & market application and so on, and makes a scientific prediction for the development industry prospects on the basis of analysis, finally, analyzes opportunities for investment in the industry at the end of the report. Through the statistical analysis, the report depicts the global and Southeast Asia total market of Dihydropyridine Market including capacity, production, production value, cost/profit, supply/demand and Southeast Asia import/export.

oints Covered of this Dihydropyridine Market report are:To share detailed information about the key factors such as manufacturers, raw material suppliers, equipment suppliers, end users, traders, distributors and etc.The historical data from 2014 to 2019 and forecast data from 2020 to 2026.

For competitor segment, the report includes global key players of Dihydropyridine Market as well as some small players. The information for each competitor includes:

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The Dihydropyridine Market Report analysis by primary as well as secondary analysis. The Dihydropyridine Market report providing comprehensive syndicated market research reports with in-depth analysis of global trending markets and global sectors. The research experts use exclusive mixture of primary and secondary research, different analytics, and industry research to give a holistic view of the Dihydropyridine market and business ecosystem..

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Dihydropyridine Market 2020 | Know the Latest COVID19 Impact Analysis And Strategies of Key Players: Shenzhen Simeiquan Biotechnology Co.Ltd, Boc...

Protective Effects of Curcumin and its Nano-Phytosome on Carrageenan-I | JIR – Dove Medical Press

Saeideh Baradaran, 1 Akbar Hajizadeh Moghaddam, 1 Sedigheh Khanjani Jelodar, 1 Nasroallah Moradi-kor 2

1Department of Biology, Faculty of Basic Sciences, University of Mazandaran, Babolsar, Iran; 2Research Center of Physiology, Semnan University of Medical Sciences, Semnan, Iran

Correspondence: Nasroallah Moradi-korResearch Center of Physiology, Semnan University of Medical Sciences, Damghan Road, P.O. Box 35195-163, Semnan, IranEmail moradikor.nasroallah@yahoo.comAkbar Hajizadeh MoghaddamDepartment of Biology, Faculty of Basic Sciences, University of Mazandaran, P.O. Box 57416-13534, Babolsar, IranEmail a.hajizadeh@umz.ac.ir

Background and purpose: Natural compounds are used for prevention of inflammation. Curcumin has antioxidant and anti-inflammatory properties, and loading it into nano-phytosomes may improve its efficiency. The present study investigates the effects of curcumin and its nano-phytosome on behavioral and biochemical responses in carrageenan-induced inflammation in the mice model.Methods: The mice were divided into six groups and received oral administration of curcumin or its nano-phytosome at a dose of 15 mg/kg for seven days before the administration of carrageenan. Acute inflammation in the mice was induced by administration of carrageenan (1%) into the subplantar region of the left paw. Antioxidant activity and behavioral responses were then evaluated.Results: The results showed that the serum concentrations of antioxidant enzymes were significantly higher in the sal+sal group compared to the cara+sal group (P< 0.05). Using nanophytosome, separately and in combination with indomethacin, increased the levels of antioxidant enzymes compared to the cara+sal group (P< 0.05). Latency was significantly lower in the cara+sal group compared to the cara+sal group (P< 0.05), but it was considerably higher in other groups, especially in the cara+nano.ph.cur+indo group (P< 0.05).Conclusion: It can be stated that the nano-phytosome of curcumin could improve antioxidant and behavioral responses in inflamed mice.

Keywords: antioxidant activity, inflammation, mice model, nano-phytosome

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

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Protective Effects of Curcumin and its Nano-Phytosome on Carrageenan-I | JIR - Dove Medical Press

Global Biochemistry Analyzer Market Growth to Thrive with Technology Advancement by 2025 Dagoretti News – Dagoretti News

The latest insightful research study on the Global Biochemistry Analyzer Market 2020 released byMarket Research Explorecomprises valuable comprehension of vital facets in the global Biochemistry Analyzer industry. The report carries our significant elements such as market scope, history, structure, performance, maturity, trends, and growth potential with expansive analysis. It also enlightens precise sales, revenue, demand, production, and growth rate forecasts up to 2025, which have been extracted from a thorough survey of historical and current market performance.

The global Biochemistry Analyzer market report also sheds light on the most significant factors of the market, which includes market segmentation, competitive landscape, industry environment, and leading players profiles. Additionally, the report highlights changing market dynamics, restraints, limitations, entry barriers as well as strained pricing structure, market fluctuations, variations, and growth driving forces that could possibly influence the Biochemistry Analyzer market structure in a positive/negative way. It also executes adept analytical models such as SWOT and Porters Five Forces analysis to examine vital market factors more effectively.

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Dominant contenders in the global Biochemistry Analyzer market with detailed profiles:

Various multinational Biochemistry Analyzer manufacturers and companies are operating in the market, and are striving to fulfill the overall demand for $keywords. Current rapidly evolving industrialization is prompting players to adopt effective manufacturing techniques and perform product developments, research activities, innovations in order to set strong challenges in the Biochemistry Analyzer industry and simultaneously deliver better fit products to their customers. Companies are also performing mergers, acquisitions, and partnerships as efforts to enlarge their serving area and target ample market size.

More importantly, the report offers a complete financial assessment of companies based on gross margin, Biochemistry Analyzer sales volume, financial ratios, pricing structure, production cost, product values, profitability, and revenue. It also illuminates their product specifications, raw material sourcing strategies, concentration rate of major raw material, key vendors, manufacturing base, production processes, effective technologies, production volume, distribution networks, global presence, organizational structure, and corporate alliance. The proposed analysis will help market players intuit the strengths, weaknesses, and market positions of their rivals.

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Leading segments of the global Biochemistry Analyzer market:

The Biochemistry Analyzer types, applications, technologies, regions, and end-users are significant divisions of the market that have been intensely elaborated in the report. Each segment analysis considers its attractiveness, profitability, growth prospects, and futuristic demand. The study offers precise comprehension to market players to determine lucrative market segments for their Biochemistry Analyzer business and using appropriate business resources to maximize their gains.

Current and forthcoming market opportunities and challenges are also elucidated in the global Biochemistry Analyzer market report to assist market players to perform accordingly. Similarly, the report discovers potential market risks, obstacles, and uncertainties that could prove harmful to market growth momentum during the forecast period. Finally, the report delivers irreplaceable research conclusions that help players to build their own business and market strategies and make informed business decisions.

You can contact us at[emailprotected]in case you need detailed information or have queries regarding the market study.

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Global Biochemistry Analyzer Market Growth to Thrive with Technology Advancement by 2025 Dagoretti News - Dagoretti News

(2020-2026) Short Path Distillation Unit (SPDU) Market Size, Share, Application With Growth and Business Strategies Forecast – News Times

Los Angeles, United State, The report titled Global Short Path Distillation Unit (SPDU) Market is one of the most comprehensive and important additions to QY Researchs archive of market research studies. It offers detailed research and analysis of key aspects of the global Short Path Distillation Unit (SPDU) market. The market analysts authoring this report have provided in-depth information on leading growth drivers, restraints, challenges, trends, and opportunities to offer a complete analysis of the global Short Path Distillation Unit (SPDU) market. Market participants can use the analysis on market dynamics to plan effective growth strategies and prepare for future challenges beforehand. Each trend of the global Short Path Distillation Unit (SPDU) market is carefully analyzed and researched about by the market analysts.

Global Short Path Distillation Unit (SPDU) Market is estimated to reach xxx million USD in 2020 and projected to grow at theCAGR of xx% during 2020-2025. According to the latest report added to the online repository of QY Research the Short Path Distillation Unit (SPDU) market has witnessed an unprecedented growth till 2020. The extrapolated future growth isexpected to continue at higher rates by 2025.

Top Key Players of the Global Wood Wax Market: Buss-SMS-Canzler GmbH, GIG Karasek (Dr. Aichhorn Group), LCI Corporation (Nederman Group), VTA, 3V Tech, Sulzer, Pfaudler, Technoforce, Vobis, LLC, Wuxi Lima Chemical Machinery, Wuxi Haiyuan Biochemical Equipment, WuXi HeXiang Biochemistry Equipment, Wuxi Hengyi Chemical Machinery, etc.

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The Essential Content Covered in the GlobalShort Path Distillation Unit (SPDU) Market Report:

* Top Key Company Profiles.* Main Business and Rival Information* SWOT Analysis and PESTEL Analysis* Production, Sales, Revenue, Price and Gross Margin* Market Share and Size

By Type:Internal Diameter 500 Below, Internal Diameter 500-1000, Internal Diameter 1000 Above

By Applications:Pharmaceuticals, Chemical Industry, Food and Beverages, Petrochemical Industry, Others

Critical questionsaddressed by the Short Path Distillation Unit (SPDU) Market report

Reasons to Buy the Report

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Table of Contents

1 Short Path Distillation Unit (SPDU) Market Overview1.1 Product Overview and Scope of Short Path Distillation Unit (SPDU)1.2 Short Path Distillation Unit (SPDU) Segment by Type1.2.1 Global Short Path Distillation Unit (SPDU) Production Growth Rate Comparison by Type 2020 VS 20261.2.2 Internal Diameter 500 Below1.2.3 Internal Diameter 500-10001.2.4 Internal Diameter 1000 Above1.3 Short Path Distillation Unit (SPDU) Segment by Application1.3.1 Short Path Distillation Unit (SPDU) Consumption Comparison by Application: 2020 VS 20261.3.2 Pharmaceuticals1.3.3 Chemical Industry1.3.4 Food and Beverages1.3.5 Petrochemical Industry1.3.6 Others1.4 Global Short Path Distillation Unit (SPDU) Market by Region1.4.1 Global Short Path Distillation Unit (SPDU) Market Size Estimates and Forecasts by Region: 2020 VS 20261.4.2 North America Estimates and Forecasts (2015-2026)1.4.3 Europe Estimates and Forecasts (2015-2026)1.4.4 China Estimates and Forecasts (2015-2026)1.4.5 Japan Estimates and Forecasts (2015-2026)1.5 Global Short Path Distillation Unit (SPDU) Growth Prospects1.5.1 Global Short Path Distillation Unit (SPDU) Revenue Estimates and Forecasts (2015-2026)1.5.2 Global Short Path Distillation Unit (SPDU) Production Capacity Estimates and Forecasts (2015-2026)1.5.3 Global Short Path Distillation Unit (SPDU) Production Estimates and Forecasts (2015-2026)

2 Market Competition by Manufacturers2.1 Global Short Path Distillation Unit (SPDU) Production Capacity Market Share by Manufacturers (2015-2020)2.2 Global Short Path Distillation Unit (SPDU) Revenue Share by Manufacturers (2015-2020)2.3 Market Share by Company Type (Tier 1, Tier 2 and Tier 3)2.4 Global Short Path Distillation Unit (SPDU) Average Price by Manufacturers (2015-2020)2.5 Manufacturers Short Path Distillation Unit (SPDU) Production Sites, Area Served, Product Types2.6 Short Path Distillation Unit (SPDU) Market Competitive Situation and Trends2.6.1 Short Path Distillation Unit (SPDU) Market Concentration Rate2.6.2 Global Top 3 and Top 5 Players Market Share by Revenue2.6.3 Mergers & Acquisitions, Expansion

3 Production Capacity by Region3.1 Global Production Capacity of Short Path Distillation Unit (SPDU) Market Share by Regions (2015-2020)3.2 Global Short Path Distillation Unit (SPDU) Revenue Market Share by Regions (2015-2020)3.3 Global Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)3.4 North America Short Path Distillation Unit (SPDU) Production3.4.1 North America Short Path Distillation Unit (SPDU) Production Growth Rate (2015-2020)3.4.2 North America Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)3.5 Europe Short Path Distillation Unit (SPDU) Production3.5.1 Europe Short Path Distillation Unit (SPDU) Production Growth Rate (2015-2020)3.5.2 Europe Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)3.6 China Short Path Distillation Unit (SPDU) Production3.6.1 China Short Path Distillation Unit (SPDU) Production Growth Rate (2015-2020)3.6.2 China Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)3.7 Japan Short Path Distillation Unit (SPDU) Production3.7.1 Japan Short Path Distillation Unit (SPDU) Production Growth Rate (2015-2020)3.7.2 Japan Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)

4 Global Short Path Distillation Unit (SPDU) Consumption by Regions4.1 Global Short Path Distillation Unit (SPDU) Consumption by Regions4.1.1 Global Short Path Distillation Unit (SPDU) Consumption by Region4.1.2 Global Short Path Distillation Unit (SPDU) Consumption Market Share by Region4.2 North America4.2.1 North America Short Path Distillation Unit (SPDU) Consumption by Countries4.2.2 U.S.4.2.3 Canada4.3 Europe4.3.1 Europe Short Path Distillation Unit (SPDU) Consumption by Countries4.3.2 Germany4.3.3 France4.3.4 U.K.4.3.5 Italy4.3.6 Russia4.4 Asia Pacific4.4.1 Asia Pacific Short Path Distillation Unit (SPDU) Consumption by Region4.4.2 China4.4.3 Japan4.4.4 South Korea4.4.5 Taiwan4.4.6 Southeast Asia4.4.7 India4.4.8 Australia4.5 Latin America4.5.1 Latin America Short Path Distillation Unit (SPDU) Consumption by Countries4.5.2 Mexico4.5.3 Brazil

5 Production, Revenue, Price Trend by Type5.1 Global Short Path Distillation Unit (SPDU) Production Market Share by Type (2015-2020)5.2 Global Short Path Distillation Unit (SPDU) Revenue Market Share by Type (2015-2020)5.3 Global Short Path Distillation Unit (SPDU) Price by Type (2015-2020)5.4 Global Short Path Distillation Unit (SPDU) Market Share by Price Tier (2015-2020): Low-End, Mid-Range and High-End

6 Global Short Path Distillation Unit (SPDU) Market Analysis by Application6.1 Global Short Path Distillation Unit (SPDU) Consumption Market Share by Application (2015-2020)6.2 Global Short Path Distillation Unit (SPDU) Consumption Growth Rate by Application (2015-2020)

7 Company Profiles and Key Figures in Short Path Distillation Unit (SPDU) Business7.1 Buss-SMS-Canzler GmbH7.1.1 Buss-SMS-Canzler GmbH Short Path Distillation Unit (SPDU) Production Sites and Area Served7.1.2 Buss-SMS-Canzler GmbH Short Path Distillation Unit (SPDU) Product Introduction, Application and Specification7.1.3 Buss-SMS-Canzler GmbH Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)7.1.4 Buss-SMS-Canzler GmbH Main Business and Markets Served7.2 GIG Karasek (Dr. Aichhorn Group)7.2.1 GIG Karasek (Dr. Aichhorn Group) Short Path Distillation Unit (SPDU) Production Sites and Area Served7.2.2 GIG Karasek (Dr. Aichhorn Group) Short Path Distillation Unit (SPDU) Product Introduction, Application and Specification7.2.3 GIG Karasek (Dr. Aichhorn Group) Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)7.2.4 GIG Karasek (Dr. Aichhorn Group) Main Business and Markets Served7.3 LCI Corporation (Nederman Group)7.3.1 LCI Corporation (Nederman Group) Short Path Distillation Unit (SPDU) Production Sites and Area Served7.3.2 LCI Corporation (Nederman Group) Short Path Distillation Unit (SPDU) Product Introduction, Application and Specification7.3.3 LCI Corporation (Nederman Group) Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)7.3.4 LCI Corporation (Nederman Group) Main Business and Markets Served7.4 VTA7.4.1 VTA Short Path Distillation Unit (SPDU) Production Sites and Area Served7.4.2 VTA Short Path Distillation Unit (SPDU) Product Introduction, Application and Specification7.4.3 VTA Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)7.4.4 VTA Main Business and Markets Served7.5 3V Tech7.5.1 3V Tech Short Path Distillation Unit (SPDU) Production Sites and Area Served7.5.2 3V Tech Short Path Distillation Unit (SPDU) Product Introduction, Application and Specification7.5.3 3V Tech Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)7.5.4 3V Tech Main Business and Markets Served7.6 Sulzer7.6.1 Sulzer Short Path Distillation Unit (SPDU) Production Sites and Area Served7.6.2 Sulzer Short Path Distillation Unit (SPDU) Product Introduction, Application and Specification7.6.3 Sulzer Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)7.6.4 Sulzer Main Business and Markets Served7.7 Pfaudler7.7.1 Pfaudler Short Path Distillation Unit (SPDU) Production Sites and Area Served7.7.2 Pfaudler Short Path Distillation Unit (SPDU) Product Introduction, Application and Specification7.7.3 Pfaudler Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)7.7.4 Pfaudler Main Business and Markets Served7.8 Technoforce7.8.1 Technoforce Short Path Distillation Unit (SPDU) Production Sites and Area Served7.8.2 Technoforce Short Path Distillation Unit (SPDU) Product Introduction, Application and Specification7.8.3 Technoforce Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)7.8.4 Technoforce Main Business and Markets Served7.9 Vobis, LLC7.9.1 Vobis, LLC Short Path Distillation Unit (SPDU) Production Sites and Area Served7.9.2 Vobis, LLC Short Path Distillation Unit (SPDU) Product Introduction, Application and Specification7.9.3 Vobis, LLC Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)7.9.4 Vobis, LLC Main Business and Markets Served7.10 Wuxi Lima Chemical Machinery7.10.1 Wuxi Lima Chemical Machinery Short Path Distillation Unit (SPDU) Production Sites and Area Served7.10.2 Wuxi Lima Chemical Machinery Short Path Distillation Unit (SPDU) Product Introduction, Application and Specification7.10.3 Wuxi Lima Chemical Machinery Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)7.10.4 Wuxi Lima Chemical Machinery Main Business and Markets Served7.11 Wuxi Haiyuan Biochemical Equipment7.11.1 Wuxi Haiyuan Biochemical Equipment Short Path Distillation Unit (SPDU) Production Sites and Area Served7.11.2 Wuxi Haiyuan Biochemical Equipment Short Path Distillation Unit (SPDU) Product Introduction, Application and Specification7.11.3 Wuxi Haiyuan Biochemical Equipment Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)7.11.4 Wuxi Haiyuan Biochemical Equipment Main Business and Markets Served7.12 WuXi HeXiang Biochemistry Equipment7.12.1 WuXi HeXiang Biochemistry Equipment Short Path Distillation Unit (SPDU) Production Sites and Area Served7.12.2 WuXi HeXiang Biochemistry Equipment Short Path Distillation Unit (SPDU) Product Introduction, Application and Specification7.12.3 WuXi HeXiang Biochemistry Equipment Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)7.12.4 WuXi HeXiang Biochemistry Equipment Main Business and Markets Served7.13 Wuxi Hengyi Chemical Machinery7.13.1 Wuxi Hengyi Chemical Machinery Short Path Distillation Unit (SPDU) Production Sites and Area Served7.13.2 Wuxi Hengyi Chemical Machinery Short Path Distillation Unit (SPDU) Product Introduction, Application and Specification7.13.3 Wuxi Hengyi Chemical Machinery Short Path Distillation Unit (SPDU) Production Capacity, Revenue, Price and Gross Margin (2015-2020)7.13.4 Wuxi Hengyi Chemical Machinery Main Business and Markets Served

8 Short Path Distillation Unit (SPDU) Manufacturing Cost Analysis8.1 Short Path Distillation Unit (SPDU) Key Raw Materials Analysis8.1.1 Key Raw Materials8.1.2 Key Raw Materials Price Trend8.1.3 Key Suppliers of Raw Materials8.2 Proportion of Manufacturing Cost Structure8.3 Manufacturing Process Analysis of Short Path Distillation Unit (SPDU)8.4 Short Path Distillation Unit (SPDU) Industrial Chain Analysis

9 Marketing Channel, Distributors and Customers9.1 Marketing Channel9.2 Short Path Distillation Unit (SPDU) Distributors List9.3 Short Path Distillation Unit (SPDU) Customers

10 Market Dynamics10.1 Market Trends10.2 Opportunities and Drivers10.3 Challenges10.4 Porters Five Forces Analysis

11 Production and Supply Forecast11.1 Global Forecasted Production of Short Path Distillation Unit (SPDU) (2021-2026)11.2 Global Forecasted Revenue of Short Path Distillation Unit (SPDU) (2021-2026)11.3 Global Forecasted Price of Short Path Distillation Unit (SPDU) (2021-2026)11.4 Global Short Path Distillation Unit (SPDU) Production Forecast by Regions (2021-2026)11.4.1 North America Short Path Distillation Unit (SPDU) Production, Revenue Forecast (2021-2026)11.4.2 Europe Short Path Distillation Unit (SPDU) Production, Revenue Forecast (2021-2026)11.4.3 China Short Path Distillation Unit (SPDU) Production, Revenue Forecast (2021-2026)11.4.4 Japan Short Path Distillation Unit (SPDU) Production, Revenue Forecast (2021-2026)

12 Consumption and Demand Forecast12.1 Global Forecasted and Consumption Demand Analysis of Short Path Distillation Unit (SPDU)12.2 North America Forecasted Consumption of Short Path Distillation Unit (SPDU) by Country12.3 Europe Market Forecasted Consumption of Short Path Distillation Unit (SPDU) by Country12.4 Asia Pacific Market Forecasted Consumption of Short Path Distillation Unit (SPDU) by Regions12.5 Latin America Forecasted Consumption of Short Path Distillation Unit (SPDU)13 Forecast by Type and by Application (2021-2026)13.1 Global Production, Revenue and Price Forecast by Type (2021-2026)13.1.1 Global Forecasted Production of Short Path Distillation Unit (SPDU) by Type (2021-2026)13.1.2 Global Forecasted Revenue of Short Path Distillation Unit (SPDU) by Type (2021-2026)13.1.2 Global Forecasted Price of Short Path Distillation Unit (SPDU) by Type (2021-2026)13.2 Global Forecasted Consumption of Short Path Distillation Unit (SPDU) by Application (2021-2026)14 Research Finding and Conclusion

15 Methodology and Data Source15.1 Methodology/Research Approach15.1.1 Research Programs/Design15.1.2 Market Size Estimation15.1.3 Market Breakdown and Data Triangulation15.2 Data Source15.2.1 Secondary Sources15.2.2 Primary Sources15.3 Author List15.4 Disclaimer

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(2020-2026) Short Path Distillation Unit (SPDU) Market Size, Share, Application With Growth and Business Strategies Forecast - News Times

How our phones became our whole lives in just 10 years, from a woman who resuscitates them – NBCNews.com

When did you last put pictures in a photo album? When did you last drop off a roll of film at a drugstore, then flip through the prints an hour later? It was probably some time before the last decade given that, at the start of 2013, more than 50 percent of American adults had a smartphone for the first time, and now more than 80 percent of us do.

Since we wrapped our fingers around the first touch-screen smartphones a decade ago, the family photo album has all but ceased to exist. But even as we no longer make albums of them, we are even more obsessed with taking pictures. We spend hours transcribing our entire lives into digits inside memory chips on our phones, and maybe posting some small percentage of them online.

These photos are our lives now we can all remember every important moment in an entire year in just a few minutes by scrolling through our camera roll. If it was notable, we took a picture. For the first time ever, we can visualize an entire life, including somebody else's.

My job is to recover these pictures and videos when things go wrong sometimes very wrong. Each day, people from all over the world reach out to the iPad Rehab Microsolderings team of former stay-at-home moms (and one dad) after one of lifes most gut-wrenching moments. They are staring at a dead phone, usually a loved one's, and realizing that the data they thought or hoped was backing up, wasnt.

It is a beloved privilege to be trusted with the responsibility to recover these memories. We get to tell families every day Great news, we got the pictures back!

But what will become of these now-recovered pictures? Will they be printed, hung up and cherished, or will they rot on a USB stick never to be seen again, after the joy of the initial reunion fades? Few of us will ever really get around to loading those pictures onto the digital frame we always mean to buy. Our pictures tend to sit there on our individual phones, unseen, secure inside a tiny chip, because we are too busy spending our lives capturing newer pictures of sushi, birthday parties and sunsets you can almost see.

On a recent trip to New York City, I signed up for the sunset viewing at the top of the Rockefeller Center and, like everyone else, I took a picture. The picture I took, though, was a picture of all the people taking pictures. Some people there never did see the sun actually set they just saw the view of the sunset through their phones, held high above their heads.

At my kids' recent holiday concert, like many a parent, I quietly ignored the principals request to turn off our cellphones and just enjoy the concert. Instead, I took a picture and posted it on social media right in the middle of the concert; the caption read, I am filled with holiday joy that the six parents near me who are secretly videotaping the concert are all holding their phones in landscape mode.

It is possible we were better off when we were restricted to 24 carefully chosen shots on a tangible roll of film.

It's hard to imagine that this has all changed so much in 10 years, but it has. We suffer from a near-constant digital information overload; there is too much choice, and way too much noise. The sum of the knowledge of humanity is stuffed into our back pockets, as is access to nearly anything it can create. In the past, buying a new lawn chair would mean standing at a store and deciding between one with green woven canvas strips and one with blue. Today, it means scrolling through endless chair variations, struggling to distinguish fake reviews from genuine, and then being haunted by nagging ads stalking us everywhere we go online. Sometimes we simply give up.

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We are part of a grand experiment: Never before have human brains been constantly exposed to the ceaseless parade of stimulation that pours from devices in our pockets.

In order to be heard above the cacophony of the internet, even our news media is forced to shout increasingly polarizing viewpoints. To deal with the sheer volume of information, our brains seek to bundle and categorize awesome or terrible and slowly lose the ability to notice and appreciate nuance. There is no longer a middle.

Through our phones, we stare into the lights of Las Vegas when we first wake up, and just before we try to sleep. How does this affect the biochemistry of our brain? We dont know for sure, but studies are already suggesting the answer is not good.

A few weeks ago, I finally decided to give it all up ... well, for one night a week. Our family started an evening of digital respite, when we turn off our phones, tablets, computers and even the television. It is just as hard as it seems, and just as amazing.

Life unplugged feels dry and brittle at first. It is painful; I dread it each week. Im dismayed to realize that feels emotionally identical to quitting smoking.

The amount of extra time, though, is phenomenal. Did you know that you can go sledding, stop by the library, make dinner and memorize all five verses of "Good King Wenceslas" before 7:00 p.m. on a Tuesday? In the second week, I laid on the bed feeling like a disgrace to my generation. What did we do with our time growing up without phones and computers? I couldnt remember. That day I spent an hour just talking with my husband about not work and not kids. When was the last time we did that?

In the third week I found myself saying yes, out of boredom, to things to which Id normally Id say no. Can we make cookies? Yes. Can we make a gingerbread house? Yes. Do you want to go cross-country skiing with me? Yes. Will you read this book with me for two solid hours tonight? Yes. Will I remember these times more than a few gigabytes of buried digital memories? Definitely.

I taught them things: We explored how to navigate without Google maps, how to live without looking up a weather forecast. They are now wholly convinced that, yes, it is indeed impossible for a human hand to break an intact egg; they know that teeth can do a fine job of it. I learned incredible details about the fabric of my childrens lives that I miss when obsessed with photo-documenting every moment.

Our phones are amazing. But we rely on them too much. We are addicted.

And, beyond that, the idea that they are helping us keep an incredible record of our lives that will persist for generations has more than a few caveats. Yes, our great-great-grandchildren will be able to get to "know" us in a way that is unprecedented if we back up our data and find ways to pass down accessing it; I'm not sure my parents' eight-tracks or boxes of slides will be so useful to my kids.

But with the increasing complexity of mobile phone security and data encryption, the ability of people like me to recover these precious memories will become more and more limited without the support of the manufacturers. Back up your data and support the right to repair, or all those pictures you're taking to show the truth of your life to your kids one day won't be worth the silicon on which they're embedded. Plus, you have to have conversations with your family or your friends about what will happen to your phone, your pictures and your entire digital footprint when you die or else large corporations and planned obsolescence will make those decisions for you in your absence.

In the meantime, though: Put your phone down. Watch a sunset. Enjoy your kid's school play as it happens. Make some cookies that exist only in your shared memories.

More from our decade reflections project:

THINKing about 2010-2019: Where we started, how we grew and where we might go

College in the U.S. is at a crossroads. Will it increase social mobility or class stratification?

The success of the 'me too' movement took a decade of work, not just a hashtag

The decade in LGBTQ: Pop culture visibility but stalled political progress

Egg freezing and IVF in the 2010s brought us the next phase in women's lib

How Netflix, Star Wars and Marvel redefined Hollywood and how we experience movies

Opioids, pot and criminal justice reform helped undermine this decade's War on Drugs

Climate change became a burning issue in the past decade, but also an opportunity

Taylor Swift, Beyonc, Rihanna, Gaga, Pink and Kesha cleared the way for women in the 2010s

Celebrities like Gwyneth Paltrow made the 2010s the decade of health and wellness misinformation

White Christian America ended in the 2010s

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How our phones became our whole lives in just 10 years, from a woman who resuscitates them - NBCNews.com

M-Club will double your donation to UM-Flint student research scholarship – University of Michigan Flint News

In 2011, the U of M Club of Greater Flint (M-Club) pledged $50,000 to create an endowment that supports student research at the University of Michigan-Flint. Over the past seven years, the club has worked to fulfill that pledge by raising money at their annual golf outing and soliciting gifts from individual members. With just a few thousand dollars left to go to reach its goal, the Club is upping the ante by offering to match any gift to the fund up to a total of $5,000.

We are very excited about completing this pledge to UM-Flint, said Barry Trantham, M-Club Scholarship Committee Chairperson. Over the long history of our club, we have donated nearly $1 million to the Ann Arbor and Flint campuses. All of us that serve on our clubs board feel that we benefited from our experience at the university and we want to increase those benefits for future students.

The M-Club has endowed and/or supported six scholarships at UM-Flint. They have also assisted dozens of construction and programming efforts. When asked why the club decided to support a research scholarship, Trantham said, Many schools refer to themselves as research institutions. Often times that research is limited to faculty and graduate-level students. At UM-Flint, however, undergraduates are afforded the opportunity to get involved in cutting-edge research projects and we want to support those efforts.

Recently, research funding like that provided by the M-Clubs endowment allowed Nicodemus Monear, a biochemistry student, the opportunity to model the effects of the Flint water crisis on the developing embryos of mothers that consumed lead-tainted water during their pregnancy.

Regarding the value of his experience, Monear said, Research places students at the frontline of things that society does not yet understand. The skills and knowledge Ive gained by conducting research has made me a better student, and someday a better employee. Research has given me a chance to apply the experience Ive gained in my classrooms and labs. Its also made me more confident in my ability to draw conclusions and to not be so invested in what I think I already know.

The M-Club recognizes the benefits research provides students and wants every person who seeks a research experience to have the opportunity. With just a few thousand dollars remaining to reach its goal of endowing a research fund at UM-Flint, the Club is asking for the support of our alumni and donors with a gift today.

Subscribe to the UM-Flint NOW newsletter. See whats new at UM-Flint NOW with the latest news, happenings, and special announcements delivered to your inbox every two weeks.

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M-Club will double your donation to UM-Flint student research scholarship - University of Michigan Flint News

Mourinho: Festive schedule against every rule of physiology, biology, biochemistry – The World Game

Spurs were involved in the early kick-off on Boxing Day, rallying from a half-time deficit at home to record a hard-fought 2-1 triumph over Brighton and Hove Albion.

However, the victory came at a cost, with Harry Winks andMoussa Sissoko both picking up yellow cards that mean the duo will be suspended forSunday's (AEDT) game at Norwich City.

Son Heung-min is also banned following his red card against Chelsea, leaving Mourinho with a lack of options -as well aslittle preparation time -for the trip to Carrow Road.

However, before his focus switched to the next game, the Portuguese took aim at the schedule.

"I cannot imagine these boys, not just my boys, but the [Graham] Potter boys, how they can play in 48 hours," Mourinho told the media.

"If you go to control the distances they run, the intensity, the breaks, if you are going to control that and if we are going to tell anyone who understands physiology, it is a crime that they are going to play football again on the 28th.

"It is against every rule of physiology, biology, biochemistry, every rule. But that is the way it is, even with three guys suspended.

"I think from the three, two of them are unfair, Sonny unfair, Winks unfair, I can only say Sissoko had a reason for the fifth yellow card. We have to go."

Tanguy Ndombele may provide a solution to the absences inmidfield after the Frenchman was not involved against Brighton.

Mourinho clarified that while the record signing from Lyon was not injured, the player had raised concerns over his physical condition prior to the game.

"I cannot say he is injured, in five minutes we start a training session and you can go to the stands and watch it, he is going to be training normally so I cannot say he is injured," Mourinho said.

"I can say that yesterday he told me he was not feeling in condition to play the game. Not based on injuries, based on fears of previous injuries that he has had since the beginning of the season.

"Feeling not ready to start the game, but I cannot say he is injured, I can say he is not in condition to start the game, which is different."

Excerpt from:
Mourinho: Festive schedule against every rule of physiology, biology, biochemistry - The World Game

Hamilton Demolitions are Another Snub to a Cohort That’s Long Felt Underacknowledged – The University Times

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Last week, students condemned Trinitys decision to demolish the biochemistry building and Roberts Laboratory at the end of the semester a typically stressful time, made far worse by demolition noise. Students labelled the decision selfish and inconsiderate, arguing that noise had made the Hamilton library a place not conducive to effective studying.

A large group of students depend on the Hamilton library as the only place they can access books in their field, and more still see it as their primary study space.

So it was a kick in the teeth for them that the College undoubtedly bound by planning restrictions and sensitive time frames failed to even consult them on a move that has clearly had a large effect on their ability to study effectively.

While the demolitions are ultimately a necessity theyre occurring to make way for the construction of Colleges new Engineering, Energy and Emerging Technologies (E3) Institute their timing has come to symbolise Colleges lack of regard for a cohort on the east end of campus that have persistently raised concerns of being underrepresented at many levels of College life.

It is remarkably negligent on Trinitys part that affected students were not involved in discussions until it was too late: while one student has been added to the key stakeholders group in order to receive updates on the demolition, this move served mainly to highlight the irony of students not being considered key stakeholders in the first place.

It was an oversight symbolic of a College strategy that prioritised capital projects over the people it exists to educate.

Were a similar demolition project undertaken in the vicinity of the Arts Block and its adjoining libraries, its safe to say that Trinity would be left in little doubt about the ire of affected students. With packed timetables, its harder for Hamilton students to make their frustrations known, and you dont have to be a great cynic to suggest that Trinitys decision-makers would have been aware at some level that its easier to slip these moves by busier students.

For students in the Hamilton, their involvement in demolition discussions is a concession that offers too little, and came too late.

Original post:
Hamilton Demolitions are Another Snub to a Cohort That's Long Felt Underacknowledged - The University Times

Canadian Study Shows Connection Between HIV, Early-Onset Menopause in Women – AJMC.com Managed Markets Network

Maggie L. Shaw

Predisposing risk factors include less than a high school education and hepatitis C coinfection.

Women living in the United States and Canada typically enter menopause between 50 and 52 years of age. Knowing that previous study results suggest the risk for early and premature menopause is greater among women with HIV, a recent Canadian study that appeared in Menopause, the journal of the North American Menopause Society, wanted to determine the average age menopause occurs, the prevalence of both early-onset (40-45 years) and premature menopause (before 40 years), and risk factors that could precipitate menopause in women younger than 45 years.

Using self-reported data from the Canadian HIV Womens Sexual and Reproductive Health Cohort Study (CHIWOS) on women aged 16 and older living with HIV, 229 women who reported they were postmenopausal (no period in the 12 months before consenting to the questionnaire to enroll in CHIWOS), when menopause occurred, female sex at birth, had at least 1 period in their lifetime, and were not pregnant or taking hormonal contraception were included in the present analysis. Being postmenopausal also included 3 subcategories of reason: spontaneous, induced (from surgery, chemotherapy, or radiotherapy), and unknown.

Compared with the usual age for menopause mentioned above, the investigators found a median age of 48 years in their study. More women also reported early menopause than premature menopause (16.6% vs 13.1%, respectively)compared with 5% and 1% in the general populationand induced menopause was more often the cause in the premature menopause group compared with those who underwent early menopause or menopause at aged 45 and older. This finding mirrors results from studies carried out in Brazil and Thailand, in which the average age of menopause of women with HIV was also younger than among the general population.

For risk factors related to any early-onset menopause, the authors first performed a univariate analysis. Having less than a high school diploma, history of smoking, recreational drug use, white ethnicity, longer duration of HIV, and history of hepatitis C were related to a greater likelihood of menopause before reaching 45. They then carried out a multivariate analyses, finding that having less than a high school diploma and hepatitis C were related risk factors for women living with HIV.

The authors caution that due to the self-reported nature of the data they used, their results may not paint a complete picture of the association of early menopause and women living with HIV. Plus, their study population has well-controlled HIV infection, with the vast majority being on antiretroviral therapy, having an undetectable viral load, and having a normal CD4 count. Extrapolating to the general population of women living with HIV in Canada may not be possible.

Therefore, they point out, determination of whether biochemical confirmation of menopause should be required in the setting of HIV infection is a dilemma that warrants further investigation and consideration.

Reference

Andany N, Kaida A, de Pokomand A, et al; CHIWOS Research Team. Prevalence and correlates of early-onset menopause among women living with HIV in Canada [published online November 4, 2019]. Menopause. doi: 10.1097/0000000000001423.

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Canadian Study Shows Connection Between HIV, Early-Onset Menopause in Women - AJMC.com Managed Markets Network

Scientists urged to boycott Israel biochemistry conference – The Electronic Intifada (blog)

Palestinian cancer patients in Gaza City protest Israels restrictions on travel for treatment, December 2016. Such restrictions are partly why academics are calling on colleagues to boycott Septembers Federation of European Biochemical Societies conference in Jerusalem.

Palestinian, Israeli and international academics are urging colleagues to boycott the 2017 congress of the Federation of European Biochemical Societies in Jerusalem next month.

Some attendees will be unaware of Israels direct attacks on Palestinians right to education, including the bombing of schools and universities, and the obstruction of access to educational sites, the scientists and academics write in a letter that has been sent to all conference speakers.

The restrictions Israel places on the teaching and research of our Palestinian colleagues have severe consequences not only on research and educational opportunities, but also on Palestinians health.

The 89 scholars calling for the boycott include researchers from leading institutions across Europe and North America.

Even though no country recognizes Israels claim to sovereignty over Jerusalem, the Federation of European Biochemical Societies conference website prominently advertises its location as Jerusalem, Israel.

It also locates the occupied Golan Heights Syrian territory as part of Israel.

Whether intentional or not, this makes the academic body a direct participant in Israels efforts to legitimize its violent occupation, annexation and colonization of these territories in violation of international law.

The conference is sponsored by several Israeli universities that are directly complicit in Israeli violations of Palestinian rights, including weapons development, support for Israels attacks on Gaza and helping recruitment for Israels secret police.

Israeli universities are also directly involved in efforts to undermine international solidarity for Palestinian rights.

The Association of University Heads of Israel, for instance, is known to help the Israeli governments efforts to censor teaching about Palestine in universities in other countries and to try to thwart the global Palestinian rights movement.

One of the themes of the conference is the biochemistry of cancer. Rates of cancer are rising, particularly for Palestinians in the blockaded Gaza Strip.

But as the scholars point out, Israel actively obstructs life-saving treatment: The five-year survival rate for breast cancer is as low as 30 percent in Gaza, which Israel has besieged for the past 10 years, as compared to 86 percent in Israel. In 2016, only 44 percent of Gaza patients who requested access to Israeli hospitals were admitted; more than half of those refused entry were cancer patients.

Meanwhile, the health system in Gaza is at the brink of collapse due to Israels severe reductions in the energy supply to the territory.

Anticipating typical arguments against the boycott, the scholars state: To be clear, the academic boycott of Israel that Palestinians have called for respects the universal principle of academic freedom as it is only directed at Israeli institutions, not individual academics. Despite the differences, it is inspired by the academic boycott of South Africa, which was called for in 1965 by 496 academics from 34 universities in the United Kingdom.

Last year, after a similar appeal, several scholars pulled out of a conference on genocide hosted by Hebrew University.

Israeli university leaders have said that they are being hit hard by a silent boycott, where many academics stay away from Israeli institutions but do not make any public statement.

Leading Israel lobby groups have also acknowledged the growing impact of the so-called silent boycott.

The scholars note that the Federation of European Biochemical Societies has itself been sensitive to political concerns regarding the location of its conferences. In 2016, the body expressed solidarity with the Turkish scientific community facing curtailment of academic freedoms in Turkey, and subsequently canceled its conference scheduled to take place there.

By organizing its congress in Jerusalem, the FEBS participates consciously or unconsciously in whitewashing Israels violent repression of Palestinian human rights, said Ahmed Abbes, research director at Frances CNRS scientific institute, and secretary of AURDIP, an academic group that supports Palestinians rights.

We hope that our colleagues will take the opportunity of consulting their consciences, listen to the voice of Palestinian civil society, and decline to cross this picket line.

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Scientists urged to boycott Israel biochemistry conference - The Electronic Intifada (blog)

Ligand (biochemistry) – Wikipedia

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose. In protein-ligand binding, the ligand is usually a molecule which produces a signal by binding to a site on a target protein. The binding typically results in a change of conformation of the target protein. In DNA-ligand binding studies, the ligand can be a small molecule, ion,[1] or protein[2] which binds to the DNA double helix. The relationship between ligand and binding partner is a function of charge, hydrophobicity, and molecular structure. The instance of binding occurs over an infinitesimal range of time and space, so the rate constant is usually a very small number.

Binding occurs by intermolecular forces, such as ionic bonds, hydrogen bonds and Van der Waals forces. The association of docking is actually reversible through dissociation. Measurably irreversible covalent bonding between a ligand and target molecule is atypical in biological systems. In contrast to the definition of ligand in metalorganic and inorganic chemistry, in biochemistry it is ambiguous whether the ligand generally binds at a metal site, as is the case in hemoglobin. In general, the interpretation of ligand is contextual with regards to what sort of binding has been observed. The etymology stems from ligare, which means 'to bind'.

Ligand binding to a receptor protein alters the chemical conformation by affecting the three-dimensional shape orientation. The conformation of a receptor protein composes the functional state. Ligands include substrates, inhibitors, activators, and neurotransmitters. The rate of binding is called affinity, and this measurement typifies a tendency or strength of the effect. Binding affinity is actualized not only by host-guest interactions, but also by solvent effects that can play a dominant, steric role which drives non-covalent binding in solution.[3] The solvent provides a chemical environment for the ligand and receptor to adapt, and thus accept or reject each other as partners.

Radioligands are radioisotope labeled compounds used in vivo as tracers in PET studies and for in vitro binding studies.

The interaction of most ligands with their binding sites can be characterized in terms of a binding affinity. In general, high-affinity ligand binding results from greater intermolecular force between the ligand and its receptor while low-affinity ligand binding involves less intermolecular force between the ligand and its receptor. In general, high-affinity binding results in a higher degree of occupancy for the ligand at its receptor binding site than is the case for low-affinity binding; the residence time (lifetime of the receptor-ligand complex) does not correlate. High-affinity binding of ligands to receptors is often physiologically important when some of the binding energy can be used to cause a conformational change in the receptor, resulting in altered behavior of an associated ion channel or enzyme.

A ligand that can bind to a receptor, alter the function of the receptor, and trigger a physiological response is called an agonist for that receptor. Agonist binding to a receptor can be characterized both in terms of how much physiological response can be triggered and in terms of the concentration of the agonist that is required to produce the physiological response. High-affinity ligand binding implies that a relatively low concentration of a ligand is adequate to maximally occupy a ligand-binding site and trigger a physiological response. The lower the Ki concentration is, the more likely there will be a chemical reaction between the pending ion and the receptive antigen. Low-affinity binding (high Ki level) implies that a relatively high concentration of a ligand is required before the binding site is maximally occupied and the maximum physiological response to the ligand is achieved. In the example shown to the right, two different ligands bind to the same receptor binding site. Only one of the agonists shown can maximally stimulate the receptor and, thus, can be defined as a full agonist. An agonist that can only partially activate the physiological response is called a partial agonist. In this example, the concentration at which the full agonist (red curve) can half-maximally activate the receptor is about 5 x 109 Molar (nM = nanomolar). Ligands that bind to a receptor but fail to activate the physiological response are receptor antagonists.

In the example shown to the left, ligand-binding curves are shown for two ligands with different binding affinities. Ligand binding is often characterized in terms of the concentration of ligand at which half of the receptor binding sites are occupied, known as the IC50, which is related to but different from the dissociation constant. The ligand illustrated by the red curve has a higher binding affinity and smaller Kd than the ligand illustrated by the green curve. If these two ligands were present at the same time, more of the higher-affinity ligand would be bound to the available receptor binding sites. This is how carbon monoxide can compete with oxygen in binding to hemoglobin, resulting in carbon monoxide poisoning.

Binding affinity is most commonly determined using a radiolabeled ligand, known as a tagged ligand. Homologous competitive binding experiments involve binding competition between a tagged ligand and an untagged ligand.[4] Real-time based methods, which are often label-free, such as surface plasmon resonance, dual polarization interferometry and Multi-Parametric Surface Plasmon Resonance (MP-SPR) can not only quantify the affinity from concentration based assays; but also from the kinetics of association and dissociation, and in the later cases, the conformational change induced upon binding. MP-SPR also enables measurements in high saline dissociation buffers thanks to a unique optical setup. Microscale Thermophoresis (MST), an immobilization-free method[5] was developed. This method allows the determination of the binding affinity without any limitation to the ligand's molecular weight.[6]

For the use of statistical mechanics in a quantitative study of the ligand-receptor binding affinity, see the comprehensive article[7] on the configurational partition function.

Binding affinity data alone does not determine the overall potency of a drug. Potency is a result of the complex interplay of both the binding affinity and the ligand efficacy. Ligand efficacy refers to the ability of the ligand to produce a biological response upon binding to the target receptor and the quantitative magnitude of this response. This response may be as an agonist, antagonist, or inverse agonist, depending on the physiological response produced.[8]

Selective ligands have a tendency to bind to very limited kinds of receptor, whereas non-selective ligands bind to several types of receptors. This plays an important role in pharmacology, where drugs that are non-selective tend to have more adverse effects, because they bind to several other receptors in addition to the one generating the desired effect.

Bivalent ligands consist of two drug-like molecules (pharmacophores or ligands) connected by an inert linker. There are various kinds of bivalent ligands and are often classified based on what the pharmacophores target. Homobivalent ligands target two of the same receptor types. Heterobivalent ligands target two different receptor types.[9] Bitopic ligands target an orthosteric binding sites and allosteric binding sites on the same receptor.[10]

In scientific research, bivalent ligands have been used to study receptor dimers and to investigate their properties. This class of ligands was pioneered by Philip S. Portoghese and coworkers while studying the opioid receptor system.[11][12][13] Bivalent ligands were also reported early on by Micheal Conn and coworkers for the gonadotropin-releasing hormone receptor.[14][15] Since these early reports, there have been many bivalent ligands reported for various GPCR systems including cannabinoid,[16] serotonin,[17][18] oxytocin,[19] and melanocortin receptor systems,[20][21][22] and for GPCR-LIC systems (D2 and nACh receptors).[9]

Bivalent ligands usually tend to be larger than their monovalent counterparts, and therefore, not drug-like. (See Lipinskis rule of five.) Many believe this limits their applicability in clinical settings.[23][24] In spite of these beliefs, there have been many ligands that have reported successful pre-clinical animal studies.[21][22][19][25][26][27] Given that some bivalent ligands can have many advantages compared to their monovalent counterparts (such as tissue selectivity, increased binding affinity, and increased potency or efficacy), bivalents may offer some clinical advantages as well.

A privileged scaffold[28] is a molecular framework or chemical moiety that is statistically recurrent among known drugs or among a specific array of biologically active compounds. These privileged elements[29] can be used as a basis for designing new active biological compounds or compound libraries.

Main methods to study proteinligand interactions are principal hydrodynamic and calorimetric techniques, and principal spectroscopic and structural methods such as

Other techniques include: fluorescence intensity, bimolecular fluorescence complementation, FRET (fluorescent resonance energy transfer) / FRET quenching surface plasmon resonance, bio-layer interferometry, Coimmunopreciptation indirect ELISA, equilibrium dialysis, gel electrophoresis, far western blot, fluorescence polarization anisotropy, electron paramagnetic resonance, microscale thermophoresis

The dramatically increased computing power of supercomputers and personal computers has made it possible to study proteinligand interactions also by means of computational chemistry. For example, a worldwide grid of well over a million ordinary PCs was harnessed for cancer research in the project grid.org, which ended in April 2007. Grid.org has been succeeded by similar projects such as World Community Grid, Human Proteome Folding Project, Compute Against Cancer and Folding@Home.

Read more here:
Ligand (biochemistry) - Wikipedia

Biochemistry Analyzer Market Analysis and Global Outlook 2019 to 2025 – Market Research Feed

The GlobalBiochemistry Analyzer Marketresearch report offers an in-depth evaluation of each crucial aspect of the worldwide Biochemistry Analyzer industry that relates to market size, share, revenue, demand, sales volume, and development in the market. The report analyzes the Biochemistry Analyzer market over the values, historical pricing structure, and volume trends that make it easy to predict growth momentum and precisely estimate forthcoming opportunities in the Biochemistry Analyzer industry.

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Global Biochemistry Analyzer market overview in brief:

The biochemistry analyzers are very safe to use and require very less to determine and analyse chemical reactions and biological processes. Biochemistry analyzers basically operate on the principle of Lamberts and Beers law of photo-chemistry.

The factors that propel the growth of the Biochemistry Analyzers Industry Market include increasing demand for biochemistry analyzers, rising geriatric population, increasing R&D activities and growing population and urbanization. The increase in laboratory automation as one of the primary growth factors for this market. Laboratory automation results in greater improvement in productivity with safer working conditions, reduced operational cost, and reduction in labor force. Additionally, automation enables the effectiveness in the identification of samples, easy storage of data, less component consumption and sample volume, reduction, less occupied laboratory space and reduction in turnaround time. the Americas is expected to be the major revenue contributor to the market due to the growing population, as well as, the high prevalence of chronic and infectious diseases.

The Biochemistry Analyzer market has been reporting substantial growth rates with considerable CAGR for the last couple of decades. According to the report, the Biochemistry Analyzer market is expected to grow more vigorously during the forecast period and it can also influence the global economic structure with a higher revenue share.

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Global Biochemistry Analyzer market overview in brief:

The report also evaluates driving forces of Biochemistry Analyzer market and changing dynamics which have been considered as growth-boosting factor. Also, the Biochemistry Analyzer study sheds light on limitations and restraints that could probably become obstruction while the Biochemistry Analyzer industry is proceeding to achieve substantial revenue. The report also aids readers to gain in-depth knowledge of a Biochemistry Analyzer market environment that comprises terms such as entry barriers, and trading policies as well as regulatory, political, financial and social concerns that may also hamper Biochemistry Analyzer market growth momentum.

TheLeading Playersinvolved in global Biochemistry Analyzer market are:

URIT Medical Electronic, ELITechGroup, EKF Diagnostics, Spinreact, Mindray, Danaher, Roche Diagnostics

Based ontype, the Biochemistry Analyzer market is categorized into:

Semi-Automatic Biochemical Analyzers, Fully Automated Biochemistry Analyzers

According toapplications, Biochemistry Analyzer market splits into:

Academic Research Institutes, Biotechnology Companies, Contract Research Organizations, Diagnostic Centres, Hospitals, Pharmaceutical Companies, Others

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Biochemistry Analyzer Market Analysis and Global Outlook 2019 to 2025 - Market Research Feed

Global Biochemistry Analyzers Market 2017- URIT Medical … – First Newshawk

The Biochemistry Analyzers Market 2017 Research Report investigates a thorough and complete study on Biochemistry Analyzers industry volume, market Share, market Trends, Biochemistry Analyzers Growth aspects, wide range of applications, Utilization ratio, Supply and demand analysis, manufacturing capacity, Price durinf Forecast period from 2017 to 2022

The research report labeled Global Biochemistry Analyzers Market 2017 presents the penetrating study of Biochemistry Analyzers market globally, concentrating on complete analysis of the present and past historical details of Biochemistry Analyzers market. The competitive landscape view of the Biochemistry Analyzers industry is also covered in this research document.

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Competitive Study of Global Biochemistry Analyzers Market 2017 Based on Key Vendors:

1 URIT Medical Electronic 2 Rayto Life and Analytical Sciences 3 ELITechGroup 4 Rayto Life and Analytical Sciences 5 EKF Diagnostics 6 Shenzhen Genius Electronics 7 Spinreact 8 Mindray

The report organizes the Biochemistry Analyzers market across the globe into distinct portion based on industry standards. It also distinguishes the market based on geographical regions. The report mainly throws light on dominant players in the regions of (United States, EU, China, and Japan). Other regions can be added accordingly.

Discrete aspects of the Biochemistry Analyzers industry like value chain analysis, Biochemistry Analyzers industry rules and policies, the factors driving the growth of the market and the constraints hampering the growth are explained.

In next section, the Biochemistry Analyzers report mentions the products that are currently available in the market along with their cost structures, manufacturing volume, requirement and supply analysis, import/export scenario and their overall contribution to the Biochemistry Analyzers market revenue globally.

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Further, the report analyzes the feasibility of investment, investment return analysis and shows a complete picture of market development scope and business strategies followed by leading Biochemistry Analyzers industry players along with their company profile, market share and contact information.

Lastly, the report enlists the vital conclusions that will assist all individuals who have a keen interest in Biochemistry Analyzers Market.

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Global Biochemistry Analyzers Market 2017- URIT Medical ... - First Newshawk

Biochemistry Analyser Market to Reach a Valuation of US$ 4625.3 Mn in Revenues during 2016-2024 – MilTech

The clinical use of biochemistry analyzers in measurement solutions such as latex agglutination, ion-selective potentiometry, and colorimetric & photometric testing. In addition to this, accuracy of biochemistry analyzers in analyzing blood and urine samples has benefited pathology labs and diagnostic centers across the globe. Persistence Market Research predicts that the global demand for biochemistry analyzers will continue to soar on the grounds of such factors. A recent report published by Persistence Market Research projects that by the end of 2024, the global market for biochemistry analyzers will reach US$ 4,625.3 Mn in terms of value.

Key findings in the report cite that the use of chemistry analyzers spans from high-throughput clinical labs to point-of-care clinics, and its use for testing enzymes, electrolytes and proteins is gaining traction. The report current values the global biochemistry analyzer market at a little over US$ 3,000 Mn. During the forecast period, revenues generated through global sales of biochemistry analyzers are, thus, expected to soar at a steady CAGR of 5.5%.

Key Research Insights from the Report include:

Roche Diagnostics GmbH, Siemens AG, Beckman Coulter Inc., Abbott Diagnostics Inc., Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Hologic, Inc., Randox Laboratories, Ltd., Awareness Technology, Inc., Transasia Biomedicals Ltd., and Nova Biomedical Corp. are profiled in the report as key players of global biochemistry analyzer market.

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The report further reveals that fully-automated biochemistry analyzers will remain in great demand in the years to come. In 2017 and beyond, more than 85% of global biochemistry analyzer revenues will be accounted by sales of fully-automated biochemistry analyzers. Moreover, clinical diagnostics will also remain the largest application of biochemistry analyzers throughout the forecast period. Revenues accounted by global sales of biochemistry analyzers in clinical diagnostics are anticipated to register speedy growth at 5.7% CAGR. The report further identifies diagnostic centers as largest end-users of biochemistry analyzers in the world. On the other hand, rising number of point-of-care diagnostic labs instated in hospitals will render a key end-user of biochemistry analyzers. Together, hospitals and diagnostics centers will be responsible for procure over two-third of global biochemistry analyzers revenues through 2024.

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The use of biochemistry analyzers in drug development applications is also expected to gain traction in the future. Based on modality, the report forecasts that in 2016, more than 70% of the market value was accounted by bench-top biochemistry analyzers. However, towards the end of the forecast period, the demand for bench-top modality will incur a marginal decline, while floor standing biochemistry analyzers will bring in over US$ 1,200 Mn revenues.

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Biochemistry Analyser Market to Reach a Valuation of US$ 4625.3 Mn in Revenues during 2016-2024 - MilTech

Paul Babitzke elected as Fellow of the American Academy of Microbiology – Penn State News

UNIVERSITY PARK, Pa. Paul Babitzke, professor of biochemistry and molecular biology at Penn State, has been elected as a Fellow of the American Academy of Microbiology. Election as a Fellow recognizes members of the American Society for Microbiology (ASM) who display excellence, originality and leadership and have made exceptional contributions to the advancement of microbiology.

Babitzke's research focuses on the regulation of gene expression where and when genes are used in a cell by RNA structure and RNA-binding proteins. He is interested in the fundamental mechanisms elongation and termination of how RNA molecules are transcribed from DNA, in addition to investigating a variety of genes in which RNA binding proteins control gene expression by transcription attenuation, repression of translation initiation, and/or mRNA stability.

Babitzke has been director of the Biochemistry, Microbiology, and Molecular Biology Graduate Program at Penn State since 2013 and director of the Center for RNA Molecular Biology in the Penn State Huck Institutes of the Life Sciences since 2009. He was elected as a Fellow of the American Association for the Advancement of Science in 2017 and is a member of the ASM, the American Society for Biochemistry and Molecular Biology, and the RNA society. He was the keynote speaker at the Federation of European Biochemical Societies - American Society for Microbiology Conference on the Biology of RNA in host-pathogen interactions in Tenerife, Canary Islands, Spain in 2014 and was honored with the Daniel R. Tershak Memorial Teaching Award in 2009.

Babitzke joined the faculty at Penn State as an assistant professor of biochemistry and molecular biology in 1994, became associate professor in 2000, and professor in 2006. Prior to that, he was a postdoctoral researcher in the Department of Biological Sciences at Stanford University from 1991 to 1994. Babitzke earned a doctoral degree in genetics at the University of Georgia in 1991 and a bachelors degree in biomedical science at St. Cloud State University in Minnesota in 1984.

Last Updated March 31, 2017

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Paul Babitzke elected as Fellow of the American Academy of Microbiology - Penn State News

RNA Biologist Kristen Lynch Appointed Chair of Department of Biochemistry and Biophysics at Penn – Newswise (press release)

Newswise PHILADELPHIA Kristen W. Lynch, PhD, has been appointed chair of the Department of Biochemistry and Biophysics, in the Perelman School of Medicine at the University of Pennsylvania, following eight years as a tenured faculty member in the department.

Dr. Lynch has a broad vision of the future of biochemistry and biophysics at Penn, said J. Larry Jameson, MD, PhD, executive vice president of the University of Pennsylvania for the Health System and dean of the Perelman School of Medicine. Her experience, talent, and collaborative spirit will foster strong ties among investigators within the department, as well as across Penn Medicine and the University. I am confident that under Dr. Lynchs leadership Penn will secure its place among the nations top biochemistry and biophysics departments.

Lynch, who is a professor of Biochemistry and Biophysics, also holds a secondary appointment in the department of Genetics and has expertise in RNA biology and immunology. Her laboratory focuses on understanding the biochemical mechanisms and regulatory networks that control alternative gene splicing in response to antigens. (Antigens are toxins and foreign substances, such as bacteria, viruses, and cells of transplanted organs, that stimulate the production of antibodies to protect an organism.)

Alternative splicing is a process in which a single gene codes for differentbut related forms of a given protein (called isoforms), each of which has similar functions. It eliminates the need for an organism to have large numbers of genes make distinctive proteins for carrying out similar functions throughout the body. Additionally, alternative splicing helps explain why humans have substantial genetic similarity with animals and insects, for example, yet such obvious physical and behavioral differences.

The Lynch laboratory specializes in understanding how alternative splicing is regulated in T cells when the cells are stimulated by an antigen during an immune response. Lynch and her team have identified more than 500 genes that undergo alternative splicing in response to T cell stimulation and have discovered some of the molecular mechanisms and signaling pathways that lead to this regulation.

She received her doctorate from Harvard University in 1996 and completed her postdoctoral training at the University of California, San Francisco. Lynch joined the Penn faculty as an associate professor in the department of Biochemistry and Biophysics in 2009, having been recruited from University of Texas Southwestern Medical Center, where she chaired the biological chemistry graduate program.

She is the author of more than 50 scientific papers in the leading journals in her field and the recipient of numerous awards and honors in recognition of her scientific achievements, including a National Science Foundation Career Award. Lynch founded and directs the campus-wide RNA Group, a central forum for investigators in and around Penn interested in RNA-related topics. Lynch has served as a director of the RNA Society, an international scientific organization; is an editor for Molecular and Cellular Biology; and has co-chaired several international meetings in the field of RNA processing.

Penn Medicine is one of the world's leading academic medical centers, dedicated to the related missions of medical education, biomedical research, and excellence in patient care. Penn Medicine consists of the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania (founded in 1765 as the nation's first medical school) and the University of Pennsylvania Health System, which together form a $5.3 billion enterprise.

The Perelman School of Medicine has been ranked among the top five medical schools in the United States for the past 18 years, according to U.S. News & World Report's survey of research-oriented medical schools. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $373 million awarded in the 2015 fiscal year.

The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania and Penn Presbyterian Medical Center -- which are recognized as one of the nation's top "Honor Roll" hospitals by U.S. News & World Report -- Chester County Hospital; Lancaster General Health; Penn Wissahickon Hospice; and Pennsylvania Hospital -- the nation's first hospital, founded in 1751. Additional affiliated inpatient care facilities and services throughout the Philadelphia region include Chestnut Hill Hospital and Good Shepherd Penn Partners, a partnership between Good Shepherd Rehabilitation Network and Penn Medicine.

Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2015, Penn Medicine provided $253.3 million to benefit our community.

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RNA Biologist Kristen Lynch Appointed Chair of Department of Biochemistry and Biophysics at Penn - Newswise (press release)

Science Day brings students to campus – The Dartmouth

by Mika Jehoon Lee | 21 minutes ago

Students from local schools with an interest in science read weather maps, planted seedlings and examined sheep brain specimens at the fifth annual Science Day held this past Saturday, April 1 at various labs on campus.

According to fourth-year biochemistry graduate student and Science Day co-organizer Jessica DeSimone, this years attendance was the highest since its launch in 2013. A total of 171 adults accompanied 231 students at the event this year. DeSimone said that close to 200 adults and 300 students RSVPd for the event, but inclement weather may have accounted for the gap between expected and actual attendance.

Science Day is a free, drop-in event that features 15-minute long scientific demonstrations and hands-on activities geared toward students in sixth to ninth grade. According to DeSimone, Science Day was created to educate local community members about science and foster students passion for the subject. DeSimone said that Science Day was hosted by the group Graduate Women in Science and Engineering over the past few years, but this year it was independently organized by DeSimone, sixth-year biochemistry student Kelly Salmon and second-year biochemistry student Sarah Valles due to leadership changes in the group. They received funding for this years event from the School of Graduate and Advanced Studies. In addition to the three organizers, around 60 graduate students from eight different departments including biology, chemistry and psychology prepared 11 total activity stations for the event this year.

In the under the microscope station, students watched worms and flies glow under microscopes. According to third-year cellular and molecular biology graduate student Timothy Gauvin, a volunteer at the station, worms and flies provide a simple system for studying various human diseases, because the three species share a lot of similarities. Gauvin added that his love for microscopes got him interested in science and that he hoped students exposure to the activity would inspire their passion for science.

I thought it was cool to look at human cells under [microscopes] and as I investigated further, there was a lot of cool stuff you could do with this, Gauvin said. Im hoping kids of various ages can see that we have a lot of cool tricks.

Local middle school student Hope Cooper, who visited the under the microscope station, said that she enjoyed looking at worms under the microscope and learning about how worms hatch. Both Cooper and her father Adam Cooper attended Science Day two years ago and said that there were more microscopes and opportunities for students to use them this year than in years past.

Adam Cooper spoke highly of the benefit of such an event for students in exposing them to subjects they might study or pursue in the future.

The exposure for our kids to see what interests they may or may not have, to be able to see what they might want to do when they grow up and what they might not want to do when they grow up, [is] just a lot of good exposure to what their future might be, Adam Cooper said.

Meanwhile, in the soil and the world beneath our feet station, volunteers including ecology, evolution, ecosystems and society graduate student Ashley Lang Gr20 helped kids learn about mycorrhizal fungi and fossils. Lang said she wanted to introduce students to mycorrhizae, which grow in symbiotic relationships with plants, because it is poorly understood and many people are unaware of its existence.

Local elementary school student Nicholas Champine said that he enjoyed participating in Langs station and appreciated learning about fungis influence on plant growth.

Local elementary school student Charleigh Olmstead said that he specifically enjoyed playing the game Jet Stream Racer in the flowing rivers of air station. According to earth science graduate student Huanping Huang, the game allows students to become pilots and learn more about jet streams and gas. Jag Olmstead, Charleighs father, said that Science Day provided an opportunity of intellectual engagement for his children, as opposed to more typical recreational activities.

[Science Day] is something for the kids to enlighten their minds, learn something new and not play video games, Jag Olmstead said.

Rong Ding, whose elementary school-aged son participated in the flowing rivers of air station, said that the event provided his son with a unique opportunity to witness and participate in scientific experiments, which is not an everyday occurrence.

Science Day attendees were also given tours of the Thayer School of Engineering, where they visited the schools laboratories and made flubber, a rubbery polymer.

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Science Day brings students to campus - The Dartmouth

Global Biochemical Reagents Market To Gain Massive Profits During Projected Timespan – The News Brok

TheGlobal Biochemical Reagents Market To Gain Massive Profits During Projected TimespanA fundamental outline of theBiochemical Reagents Marketniche is presented by the Biochemical Reagents Market report that entails definitions, classifications, applications together with industry chain framework. TheBiochemical Reagents Marketreport provides a far-reaching evaluation of necessary market dynamics and the latest trends. It also highlights the regional market, the prominent market players, as well as several market segments [Product, Applications, End-Users, and Major Regions], and sub-segments with a wide-ranging consideration of numerous divisions with their applications.

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Our Free Complimentary Sample Report Accommodate a Brief Introduction of the research report, TOC, List of Tables and Figures, Competitive Landscape and Geographic Segmentation, Innovation and Future Developments Based on Research Methodology

Some of the Major Market Players Are:

Becton, Dickinson & Company, Agilent TechnologiesInc., Merck & Co.Inc., Waters Corporation, and Abbott Laboratories. Other few key players in the biochemical reagents market are Johnson & Johnson, Siemens Healthineers, Roche Holding AG, Bio-Rad Laboratories, and Thermo Fisher ScientificInc.

Further, the report acknowledges that in these growing and promptly enhancing market circumstances, the most recent advertising and marketing details are very important to determine the performance in the forecast period and make essential choices for profitability and growth of the Biochemical Reagents Market. In addition, the report encompasses an array of factors that impact the growth of the Biochemical Reagents Market in the forecast period. Further, this specific analysis also determines the impact on the individual segments of the market.

Note In order to provide more accurate market forecast, all our reports will be updated before delivery by considering the impact of COVID-19.

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Furthermore, the study assessed major market elements, covering the cost, capacity utilization rate, growth rate, capacity, production, gross, usage, revenue, export, supply, price, market share, gross margin, import, and demand. In addition, the study offers a thorough segmentation of the global Biochemical Reagents Market on the basis of geography [ Latin America, North America, Asia Pacific, Middle & East Africa, and Europe] , technology, end-users, applications, and region.

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The Biochemical Reagents Market report is a collection of pragmatic information, quantitative and qualitative estimation by industry experts, the contribution from industry connoisseurs and industry accomplices across the value chain. Furthermore, the report also provides the qualitative results of diverse market factors on its geographies and segments.

The Biochemical Reagents Market report is an appropriate compilation of all necessary data for the residential, industrial. & commercials buyers, manufacturers, governments, and other stakeholders to implement their market-centric tactics in line with the projected as well as the prevailing trends in the Biochemical Reagents Market. Apart from this, the report also provides insightful particulars of the existing policies, laws, together with guidelines.

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Promising Regions & Countries Mentioned In The Biochemical Reagents Market Report:

Chapters Covered in Research Report are :

Chapter 1,2 :The goal of global Biochemical Reagents Market covering the market introduction, product image, market summary and development scope.

Chapter 3, 4 :Global Market Competitions by Manufacturers, Sales Volume and Market Profit.

Chapter 5,6,7:Global Supply (Production), Consumption, Export, Import by Regions like United States, Asia-Pacific, China, India, Japan. Conducts the region-wise study of the market based on the sales ratio in each region, and market share from 2015 to 2024

Chapter 8,9,10:Global Market Analysis by Application, Cost Analysis, Marketing Strategy Analysis, Distributors/Traders

Chapter 11,12 :Market information and study conclusions, appendix and data sources.

The market report also identifies further useful and usable information about the industry mainly includes Biochemical Reagents Market development trend analysis, investment return and feasibility analysis. Further, SWOT analysis is deployed in the report to analyze the key global market players growth in the Biochemical Reagents Market industry

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Key questions answered in this comprehensive study Global Biochemical Reagents Market Size, Status and Forecast 2026

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Global Biochemical Reagents Market To Gain Massive Profits During Projected Timespan - The News Brok

Biochemical superglue opens new approach to vaccine development – Phys.Org

March 31, 2017 Credit: University of Oxford

An Oxford University spinout company is developing a molecular superglue for the rapid development of vaccines targeting a range of diseases.

SpyBiotech is using 'biochemical superglue' that can facilitate the rapid development of robust and novel vaccines. The company has raised 4m at launch in seed financing to develop the technology, led by Oxford Sciences Innovation with participation from GV.

The company gets its name from the bacterium Streptococcus pyogenes (Spy), the same organism behind a number of infections including strep throat and impetigo. The team behind SpyBiotech divided Spy into a peptide, SpyTag, and a protein partner, SpyCatcher. Naturally attracted to each other, the two form a covalent bond once combined.

SpyBiotech believes that this bond is the missing link to effective development and production of highly effective vaccines. The company will initially focus on virus-like particles (VLPs), a leading technology to induce immune responses by vaccination. Discovered in 1963, VLPs have become a cornerstone of a number of vaccines. Resembling viruses but without pathogenic material, VLPs can instead be coated with bug-busting antigens. However, the two most common ways in which a VLP can be paired with antigens genetic fusion and chemical conjugation are imprecise, expensive, prone to being misassembled, and consequently can result in the failure of a vaccine.

Conversely, SpyBiotech's SpyVLP can be easily and efficiently combined with a number of antigens, and used to produce stable vaccines that induce robust antibody responses. The company plans to target infectious diseases including major viral infections at first, with a view to developing SpyVLP into a universal platform that can be adapted to target a wide variety of conditions. In particular, owing to the versatile and easy-to-use nature of SpyVLP, the technology could underpin efforts to rapidly combat future outbreaks and pandemics.

SpyBiotech will use the seed funding to get its first candidates ready for Phase I trials. During that period, SpyBiotech's founders will receive support from its investors. The founders are aiming to start a further round of funding in the near future to catalyse the development of SpyVLP and expand into other disease areas. A leadership team, including the company's first CEO, will be announced in the coming months.

Sumi Biswas, Associate Professor at the Jenner Institute, Oxford University, said: 'Researchers in the vaccine field, including us, have struggled to make effective VLPs against many diseases for a long time. We view this superglue technology as a game changer to enable faster development of effective vaccines against major global diseases. We are excited to begin the journey of taking this versatile and innovative approach forward and moving our new vaccines from the laboratory to human clinical testing.'

Oxford Sciences Innovation (OSI), the patient capital investor for Oxford University, led the 4m investment, with GV (formerly Google Ventures), an independent venture capital arm of Alphabet, joining in participation.

Lachlan MacKinnon, Principal at OSI, said: 'We see the Spy technology as the missing link in rapid and robust VLP vaccine design and see GV as a natural co-investment partner to take this forward. We are privileged to be working with four founders who bring such an impressive combination of academic prowess and clinical stage experience to the company.'

Tom Hulme, General Partner at GV, added: 'SpyBiotech has established a novel approach using platform VLP vaccine technology that shows promise in a number of addressable markets. We're looking forward to working with a team of world class scientists with extensive experience in vaccine development spanning from vaccine design through to Phase II clinical trials to develop more effective vaccines for a wide range of global diseases.'

The research underpinning SpyBiotech was developed in conjunction between researchers at Oxford University's Department of Biochemistry and Jenner Institute, with four academics joining SpyBiotech at launch. The team includes: Mark Howarth, Professor of Protein Nanotechnology; Sumi Biswas, Associate Professor of Vaccinology; Simon Draper, Professor of Vaccinology; and Dr. Jing Jin. Combined, the founding team has taken twelve products to Phase I and II trials; filed nine patents on vaccines and other technologies; and has extensive experience in biotech and industrial collaborations and partnerships. The commercialisation of SpyBiotech's technology and company formation is supported by Oxford University Innovation, the research commercialisation company of Oxford University.

Carolyn Porter, Deputy Head of Technology Transfer at Oxford University Innovation, said: 'SpyBiotech punctuates research that's been developing for some time here at Oxford, and is a testament to the benefits of collaboration between our departments and institutes. Oxford is playing a leading role in developing the next generation of vaccines, and SpyBiotech and other spinouts working in this sector showcases the potential impact the University can have on the wider world.'

Explore further: Synthetic biologists use bacterial superglue for faster vaccine development

An interdisciplinary team of Oxford University researchers has devised a new technique to speed up the development of novel vaccines.

The Jenner Institute at Oxford University, together with partners Imaxio and GSK, has started a phase I clinical trial of a novel vaccine candidate aimed at blocking transmission of malaria.

Although many infectious diseases lack vaccines, current vaccine research is limited, primarily due to an understandable but unfortunate lack of commercial interest. A new article identifies and discusses the gaps in human ...

A spin-out from the University of Helsinki, Valo Therapeutics is developing novel oncolytic viral vaccines for the treatment of multiple forms of cancer. The therapeutic platform is projected to target cancer by recruiting ...

Scientists have identified new ways to provide vaccines against polio, which do not require the growth of live virus for their manufacture.

A new method to produce a stable fragment of poliovirus could enable safer production of vaccines, according to a study published in PLOS Pathogens.

(Phys.org)A team of researchers from several institutions in China and the U.S. has developed a way to use platinummolybdenum carbide to catalytically release hydrogen from methanol and water to power a hydrogen fuel ...

Some genetic mutations can cause a virus to flourish. Others make the virus wither away, unable to function normally and reproduce. Yet other genetic mutations only show their hand under certain conditions.

(Phys.org)A team of chemists at the University of California has developed a cheaper way to functionalize unactivated alkanes (hydrocarbons such as ethane, methane and propane) by using much more abundant catalysts. In ...

High energy, ultraviolet radiation from the Sun is a known to hazard to life, yet the energy provided by our star has played an important role as the essential driver of life on Earth.

A newly developed small molecule selectively kills the pathogen causing sleeping sickness and Chagas disease. Scientists from the Helmholtz Zentrum Mnchen, along with colleagues from the Technical University of Munich and ...

Ceramic textiles, improved jet engine blades, 3-D printed ceramics and better batteries may soon become a reality, thanks to a recently patented polymer from a Kansas State University engineer.

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Biochemical superglue opens new approach to vaccine development - Phys.Org