The British Journal of Hospital Medicine in conjunction with the Parkinson's Disease Society is delighted to announce its 12th National Parkinson's Conference. Parkinson's 2010 is aimed at all health and social care professionals involved in the clinical management of people with Parkinson's. It will be an educational event providing a state-of-the art update on the current clinical developments taking place in the field.
Participants will benefit from receiving:

THE NEW YORK ACADEMY OF MEDICINE Jointly Sponsored with the INTERNATIONAL COLLEGE OF ACUPUNCTURE & ELECTRO-THERAPEUTICS, Permanently Chartered by the University of the State of New York, State Education Department Seminar & Workshop on ACUPUNCTURE & ELECTRO-THERAPEUTICS in Clinical Practice Licensed Physicians and Dentists can earn credit hours toward the Acupuncture Certificate to practice acupuncture (300 credit hours). 25 credit hours can be earned by attending one 3-day weekend (Friday - Sunday) session.

After a sell-out year for 2012, we are delighted to announce that you can now book your place on â??Dementias 2013â??, which will be taking place on the 7th & 8th February2013 in London at the beautiful Institute of Engineeringand Technology (IET). Dementias 2013 has become anessential event in the calendar of all those with aninterest in old age psychiatry. Once again expertsProfessor Tom Arie and Professor Alistair Burns have puttogether another outstanding programme.Source:
http://www.hon.ch/cgi-bin/confevent?aff2+CONF13630

This master class will encourage nurses who are responsiblefor the assessment of older people to â??think outside theboxâ?? beyond the normal formalities of form filling toquestion what is the most appropriate assessment at aparticular point in time. The aim is to broaden a generalknowledge base of different assessments available and toenhance the quality/transferability of completed assessments. We all have limited time to assess â?? thismaster class will help you to get the most from yourassessment and conserve valuable nursing time. Most of allthe concept of the â??one size fits allâ?? assessment will bechallenged in order to introduce new ways of assessing.Source:
http://www.hon.ch/cgi-bin/confevent?aff2+CONF13732

Following this course, the participant should be able toidentify causes of the disorders described; implement adifferential diagnosis and laboratory assessment plans;outline the therapeutic intervention, possible complicationsand preventive measures. This activity is expected to resultin increased confidence in making an appropriate diagnosisand providing effective treatment and referral or follow-upcare with the overall goal of improving patient outcomes.Source:
http://www.hon.ch/cgi-bin/confevent?aff2+CONF13428

As Scientific Directors, it is a great privilege to inviteyou to participate to the 11th Anti-Aging Medicine WorldCongress in Monte-Carlo to be held under the High Patronageof S.A.S. Le Prince Albert II de Monaco. We have prepared anoutstanding program in line with our commitment toinnovation, expertise, and excellence, sharing a wealth ofexperience as well as teaching-skills. This year, AMWC willbe honouring Russia and the countries of the FSU. TheScientific Committee of the AMWC has designed a large andmature program with international faculty members from over95 countries. As well as to keeping up with worldwidepractice, this will contribute to the enhancement of yourown savoir-faire. Constantly on the lookout for thedevelopment of Preventive and Anti-Aging Medicine, the AMWC2013 will propose accordingly numerous advanced academic andclinical sessions with lectures presented by prominentexperts in the field as well as from research centers anduniversities. We also hope and are confident that you willenjoy your visit of the very exclusive and elegantPrincipality of MONACO! We look forward to welcoming you tothe AMWC 2013.Source:
http://www.hon.ch/cgi-bin/confevent?aff2+CONF13779

Posted on June 20, 2017, 6 a.m. in Longevity Genetic Research

According to a new study, a deletion in d3-GHR, a growth hormone receptor gene, is linked to an average of ten extra years of life among men.

Pinpointing specific genetic factors tied to longevity in human beings has been quite the challenge. A recent study shows that whether or not there has been a deletion of the growth hormone receptor genes exon 3 (d3-GHR) may play an important role.The research results were recently published this past Friday in the journalScience Advances.

Details About the Finding

About 840 individuals from long-lived populations were studied.The researchers found that males with the mutation deletions in d3-GHR tend to live an average of 10 years longer than those without the mutation. It is interesting to note this effect was limited to men. There was no difference noted in the women.

The deletion of d3-GHR still allows for the existence of a functional protein that boosts longevity. The study's co-author, Gil Atzmon, describes the finding as phenomenal. Atzmon is a geneticist at Albert Einstein's College of Medicine as well as the University of Haifa, located in Israel. Atzmon states the result is more accurate and globally translated as his colleagues observed the same pattern across nearly half a dozen different populations. They include those who participated in the Cardiovascular Health Study, those who participated in the French Long-Lived Study, the Old Order Amish and Ashkenazi Jews. The director of genome informatics with the Scripps Translational Science Institute, Ali Torkamani, commented that the results look convincing from his perspective.

What was of particular interest, is that Atzmon and his research team determined the men with two replicas of the d3-GHR deletion were an average of an inch taller than other men. This is the exact opposite of what the research team expected. They suspect the mutation alters the receptor's response to increases in growth hormone during instances such as pubertal growth spurts. They also suspect the mutation limits the responses to growth hormone as one passes into the adult years, spurring a slower division of cells and reducing the rate at which aging occurs.

Why the Results Matter

The research results raise the question of whether it is prudent to prescribe growth hormone to patients in an effort to restore or maintain a body that is more youthful. The study's co-author, Nir Barzilai, a geneticist with the Albert Einstein College of Medicine, has expressed concern that providing such treatments might actually be more likely to produce the opposite result of what was originally intended.

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Longer Life Span with Genetic Mutation - Anti Aging News

June 6, 2017 The roundworm, C. elegans, is a popular model in aging research because its short lifespan allows scientists to quickly assess the effects of anti-aging interventions, including genetic manipulation and drug therapies. Scientists at the MDI Biological Laboratory used C. elegans as a model to identify markers of healthy aging. The study will help scientists assess the tradeoffs between lifespan and health span in humans. Credit: MDI Biological Laboratory

Exactly when does old age begin? Which health markers best predict who will live a long and healthy life versus a life spent in poor health?

Developing metrics to help answer these questions and to understand the tradeoffs between lifespan and health span is the subject of a recent paper by MDI Biological Laboratory scientists in Journals of Gerontology: Biological Sciences, a publication of the Gerontological Society of America.

The authors studied various parameters of health in short-lived strains of the roundworm, C. elegans, with the goal of developing an empirical definition of the onset of old age, and of teasing out which health markers are most predictive of a long and healthy life.

With the development of new genetics tools, scientists are getting closer to developing therapies to extend human lifespan, but the effect of such therapies on health span (the proportion of life spent in good health) is unclear. While it used to be thought that therapies to extend lifespan would also extend health span, new research is showing that may not always be true.

The growing number of anti-aging therapies on the horizon creates a need for the development of new parameters to assess healthy aging. Instead of striving to only to prolong longevity, as has been the case in the past, the use of such tools will allow scientists to focus their efforts on lifespan-enhancing therapies with the greatest positive effects on health.

"All anti-aging interventions aren't created equal," said post-doctoral researcher Jarod Rollins, Ph.D., one of the study's lead investigators. "A recent study in C. elegans found, for instance, that the proportion of life spent in a frail state is longer in long-lived mutants than in wild-type animals. Our research is aimed at developing tools to help scientists assess the effect of lifespan-enhancing interventions on health span."

The molecular mechanisms of aging are a focus of research at the MDI Biological Laboratory, located in Bar Harbor, Maine, which is pioneering new approaches to regenerative medicine focused on the development of drugs to increase healthy lifespan by enhancing the body's innate ability to repair and regenerate lost or damaged tissues and organs.

Rollins works in the laboratory of Aric Rogers, Ph.D., the lead author of the study, in the institution's Kathryn W. Davis Center for Regenerative Biology and Medicine.

C. elegans is a popular model in aging research because its short lifespan of only two to three weeks allows scientists to quickly assess the effects of anti-aging interventions, including genetic manipulation and drug therapies. The tiny, soil-dwelling roundworm also has other advantages for research: it shares many of its genes with humans and its health markers roughly correspond to those in humans.

One marker that the MDI Biological Laboratory scientists found to be predictive of a healthy lifespan in C. elegans was movement speed. Movement speed corresponds to walking speed in humans, which studies have found to be an accurate predictor of longevity. One of the scientists' next steps will be to further develop movement speed as a marker for assessing the effect of anti-aging interventions in C. elegans.

"As science closes in on the mechanisms underlying aging, the tradeoffs between lifespan and health span become a greater cause for concern," said Kevin Strange, Ph.D., president of the MDI Biological Laboratory. "The scientists in the Rogers laboratory are at the forefront of developing metrics to assess the impact of anti-aging interventions on quality of life."

Explore further: Research sheds light on mechanisms underlying aging

More information: Jarod A. Rollins et al. Assessing Health Span in Caenorhabditis elegans: Lessons From Short-Lived Mutants, The Journals of Gerontology: Series A (2017). DOI: 10.1093/gerona/glw248

(Medical Xpress)A large team of researchers from the Netherlands, Italy and the U.S. has found a possible explanation for the injury and death to patients in a clinical trial held last year in France. In their paper published ...

(HealthDay)Exercise doesn't just trim your tummy. It may also improve bone thickness, boost bone quality, and whittle away the fat found inside bones, new animal research suggests.

Despite many studies looking at which bread is the healthiest, it is still not clear what effect bread and differences among bread types have on clinically relevant parameters and on the microbiome. In the journal Cell Metabolism ...

Yale scientists produced increased grooming behavior in mice that may model tics in Tourette syndrome and discovered these behaviors vanish when histaminea neurotransmitter most commonly associated with allergiesis ...

Some bodily activities, sleeping, for instance, mostly occur once every 24 hours; they follow a circadian rhythm. Other bodily functions, such as body temperature, cognitive performance and blood pressure, present an additional ...

Delivering drugs to the brain is no easy task. The blood-brain barrier -a protective sheath of tissue that shields the brain from harmful chemicals and invaders - cannot be penetrated by most therapeutics that are injected ...

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Living long and living well: Is it possible to do both? - Medical Xpress - Medical Xpress

PureTech will take on the development of two mTORC1 inhibitors from Novartis aimed at stopping the decline of the immune system associated with age.

Novartis is building up the portfolio of PureTech is a Boston-based healthcare company listed on the London stock market. Originally an investment firm, it now has put together a drug pipeline from its biotech portfolio. Its latest additionsare twodrugs to prevent and treat diseases related toimmunosenescence, an age-related process that reduces the immune systems functions.

PureTech will create a subsidiary, resTORbio, to carry out the development, starting with a Phase IIb trial for age-related immune system deterioration. The US company has allocated 14M ($15M) for the program, giving it a 58% stake that could rise to 67% in the future with an additional 9M ($10M) investment.

For its part, Novartis will get an undisclosed equity stake in the company plus milestonepayments and royalties as the drug advances through development and commercialization. The big Swiss pharma has already run two Phase IIa studies in elderly patients with the two mTORC1 inhibitors.

The immune system progressively loses its function with age, leading to age-related disorders

Novartis already has an mTOR inhibitor in the market, Everolimus, used as an immunosuppressant for organ transplantation and certain forms of cancer. Preclinical research seemed to indicate that this drug could also extend the lifespan and boost the efficacy of vaccines, which led the company to start human trials.

However, despite the promising potential of the candidates, Novartis has decided to trust someone else with developmentand waitto see whether theyre successful in the long term.

The field ofanti-aging,focused on delaying and preventing age-related conditions, is still young and so far it mostly attracts innovative biotech companies rather than traditional pharma. But as medicine advances and the human lifespan increases, Im sure it will start gaining more and more recognition.

Images from Africa Studio /Shutterstock;Dorrington MG and Bowdish DME (2013)Front. Immunol. 4:171.

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Novartis puts the Development of two Anti-Aging Drugs in American Hands - Labiotech.eu (blog)

Human fat could be the answer to more effective anti-aging treatments, researchers at the University of Pennsylvania say.

The researchers at Penn's Perelman School of Medicine said Friday they discovered adult stem cells from fat are more stable than other stem cells, such as those taken from skin, that are currently used in a variety of anti-aging treatments.

The cells from fat, called adipose-derived stem cells (ASCs), have the ability to make more protein that originally thought, therefore allowing them to replicate and maintain their stability.

Our study shows these cells are very robust, even when they are collected from older patients, said lead author Ivona Percec, MD.

The discovery "can potentially open the door" for new treatments and therapies to address aging-related diseases.

The researchers noted that ASCs are not currently approved for direct use by the Food and Drug Administration. They said more research is needed before potential implementation of their finding.

The finding was published in the February edition of the "Stem Cells" medical journal.

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How fat could lead to more effective anti-aging treatments - PhillyVoice.com

SERVING BEVERLY HILLS AND LOS ANGELES, CALIFORNIA

At Rejuvalife Vitality Institute, Medical Director, Dr. Andre Berger takes a holistic and comprehensive approach to helping patients improve their current state of health, prevent age-related diseases, and gain more enjoyment and fulfillment out of life. Dr. Berger firmly believes that achieving and maintaining good health requires a balanced, integrative approach to wellness that cares for the whole person. He is dedicated to helping you prevent many of the illnesses and diseases associated with the imbalance of hormones and help patients age healthy and gracefully.

Dr. Berger helps each patient individually address age-related concerns. Our philosophy of individual monitoring and safe medical management is woven throughout every facet of our practice Because this process is unique to every individual, an in-person consultation with Dr. Berger is crucial to help develop your customized treatment plan to address your unique needs. Please call 310-276-4494 today to schedule a consultation at our Beverly Hills Office.

Your personalized treatment plan will help slow the aging process to help you look and feel better. Dr. Bergers anti-aging program can address a wide range of age-related issues.

Dr. Berger offers a wide range of anti-aging services to ensure all your goals are fully addressed. Depending on your unique needs, your customized treatment plan may include:

We offer a comprehensive age management program that treats your entire body in order to combat the effects of aging. Our anti-aging program is a customized treatment plan that combines the best of Eastern and Western medicine. Dr. Berger will address numerous issues including lifestyle, hormone imbalances, lack of sexual interest, hot flashes, menopausal symptoms, low testosterone, low energy levels, mood swings, sleep issues, and reduced muscle mass with or without weight gain. These problems may occur on their own or in combination with each other and other age-related issues such as body contouring struggles and skin imperfections all of which can be addressed through a personalized treatment plan from Dr. Berger.

Click here to learn more about our Anti Aging treatment program.

In order to honor his commitment of helping you attain and maintain total health and wellness and because his philosophy requires a balanced approach that cares for the whole person, Dr. Berger invests the time needed with each patient. He believes that patient and physician develop a clear understanding of and respect for each other as he listens carefully and sensitively to your concerns. Realistic goals will be set, trust established and a treatment plan will be developed. Dr. Berger employs a comprehensive approach to help maximize your youthful life span and achieve a more energetic, beautiful health body and radiant appearance.

Dr. Berger is a leader in anti-aging, wellness and cosmetic medicine, he possesses a unique combination of skills that make him a true specialist in his field. He is also a teacher/trainer to other global physicians who choose to sit under his tutelage and learn his life-changing methods. His techniques, for rejuvenating your health and appearance, effectively integrate Eastern philosophies with world-class Western medical technologies. With an artistic eye, keen sense of aesthetics and his knowledge of science, Dr. Berger offers transformative results that will not only help you look great, but also help you feel your absolute best.

You can learn more about Dr. Bergers anti-aging principles by reading Dr. Bergers book, The Beverly Hills Anti-Aging Prescription. We also recommend that you read our Anti-Aging FAQ page for additional information.

Please contact Rejuvalife Vitality Institute using the form at the right side of the page or call 310-276-4494 today to learn how to begin the process with an anti-aging consultation. Dr. Andre Berger serves patients in Beverly Hills and Los Angeles, California

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Look and Feel More Youthful with Anti Aging Medicine in ...

SENS5 is the fifth in a unique series of conferences thatbrings together researchers and laypeople interested inresearch leading to the application of regenerative medicineto the problem of aging. Since aging affects the body at alllevels of organisation, a large number of otherwiseunrelated disciplines are represented, including stem cells,immunotherapy, cancer, neurodegeneration, gene therapy andtissue engineering.

In addition to the traditional comprehensive medical checkup, age-related physical changes as well as signs and symptoms of aging can be identified by examining blood vessels, hormone levels, functions of sensory organs, balance between active oxygen and antioxidant potential, and others. These examinations enable early detection and treatment as well as lifestyle guidance to prevent aging-related diseases. It is crucial to identify the signs of aging and take appropriate measures as early as possible. The basic elements of clinical anti-aging medicine consist of measures to improve the lifestyle of patients: dietary advice, including guidance on the use of nutritional supplements, exercise programs, and stress control.

When selecting a therapy, the risks and benefits of each therapy should be examined with the utmost importance placed on safety. Some medical institutions may use hormone replacement therapy. Others may use chelation therapy, the evidence for which is, while not abundant, considered to demonstrate efficacy in removing heavy metals from the body.

Approaches taken in different areas Areas covered by anti-aging medicine (from specialized areas to covering the whole body)

Internal medicine Metabolism Cardiovascular Digestive tract Endocrine Respiratory

Neurology Cerebrovascular disorder Alzheimers disease Stress

Orthopedics Muscle weakness Osteoporosis Osteoarthritis

Ophthalmology Presbyopia Cataract Age-related macular degeneration

Obstetrics and gynecology Menopausal disorders Late childbearing Hormonal issues

Urology Sexual dysfunction Male climacteric disorder Prostate disorder/hormonal issues

Dermatology Photoaging Senile dermatitis

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Japanese Society of Anti-aging MedicineENGLISH

Los Gatos Longevity Institute is the first and foremost medical provider of longevity/anti-aging/age management Medicine dedicated to the proposition that:

age is a state of mind ... aging is a treatable condition

As pioneers in the rapidly expanding age management / anti-aging field, we are increasingly imitated -- but never duplicated. Accept nothing but the best. We are the brand name in age management / anti-aging and Longevity Medicine proudly serving you since 1996.

Now relax ... take in a few deep breaths of air. Really deep ... Good. Now enjoy yourself.

Feel free to navigate our site in its entirety. There is a wealth of information here that should begin to answer many of your first anti-aging questions. You can see our specialty areas to the left.

We have a full spectrum of offerings including professional consultations. Bookmark this site and return often. New information is constantly being added and revised as recent developments are announced.

Your questions are welcomed. You can email us, click on our brief feedback page or call us at 408-358-8855 any time of the day.

And, don't forget to ask us about our Premiere Age Management Plans. It's like internal Plastic Surgery.

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age management (anti-aging medicine): Los Gatos Longevity ...

Who We Are

We are passionate about serving our patients with the most advanced medical treatments available in Roseville, CA. Dr. McCrory has years of experience and knowledge in his specialized healing treatments including anti-aging, pain management, EWOT, Prolozone Therapy, and Hormone Therapy.

Demonstrating a compassionate and caring manner in all of our treatments and services is our first priority.

Our mission is to make every effort to do whatever is necessary so that everyone we come in contact with has the opportunity to be proactive in their health. Establishing common sense treatment strategies that both prevent disease, slow the aging process, and optimize productive living.

At Roseville Medical, we strive to present a program of wellness care for our patients so they may gain and benefit a healthier lifestyle.

Our advanced and accurate treatments are designed to be an exact match to your wellness needs. We proudly utilize the most sophisticated technologies to find the root cause of your illness or pain.

Dr. McCrory is one of only a few hundred medical professionals who have obtained both chiropractic and medical degrees. We help our patients to regain vigor and well-being to look and feel youthful and healthy.

Dr. McCrory is one of only a few hundred physicians in the U.S. who has obtained both chiropractic and medical degrees.

Exercise With Oxygen Therapy

Roseville Advanced Medical Group is pleased to announce a proven medical technology that promises to dramatically improve peoples health and sense of well-being, increase mental and physical stamina, and inhibit the aging process. EWOT exercise with oxygen therapy is a means of improving oxygenation of the tissues of the body, increasing energy production in the cells, and thereby enhancing the vitality and health of the individual.

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Medical Chiropractic & Anti-Aging Treatment | Dr. McCrory MD

A number of products, including diets, drugs and supplements, are promoted to have anti-aging properties. Unfortunately, the hype is often undeserved. Here, I review the most famous products aimed at delaying the aging process and the misconceptions in which most--but not all--are based. Future anti-aging therapies and some advice on healthy lifestyles is also included.

Caloric Restriction Hormonal Therapies Antioxidants Telomere-Based Therapies Stem Cells ALT-711 Future Therapies The Not-So-Secret Guide to a Long, Healthy Life Conclusions

Keywords: ageing, anti-oxidants, anti-aging pill, anti-aging products, antiaging, biomedical gerontology, elderly, eternal youth, growing young, healthy aging, old age, rejuvenation, science of longevity

I will be clear from the start: presently, there is no proven way to delay, even if slightly, the human aging process (Olshansky et al., 2002; Hayflick, 2004). Although companies, and often journalists and admittedly scientists too, like to tout whatever-anti-aging-product-is-currently-in-the-news as the "fountain of youth" or the "holy grail", the truth is we do not know of any way to even slightly delay the aging process, much less stop or reverse it (which is what the "fountain of youth" and the "holy grail" are all about). Unfortunately, understanding why a given anti-aging intervention is fantasy rather than science often requires time to gather the scientific data, which not everyone is willing or capable to do (Warner et al., 2005). If you are visiting this website to learn more about anti-aging science and longevity, rather than find out about the latest anti-aging trends in Hollywood, then the discussion below is for you.

It is important to note that it is possible to delay some of the many effects of aging. For example, if you avoid unprotected exposure to the sun, you can delay skin aging. Similarly, a balanced diet can lower the incidence of heart disease. Given the complexity of aging, however, delaying the onset of a single age-related disease cannot scientifically be considered as equivalent to delaying the aging process as a whole (Hayflick, 2004). Just because a given product or lifestyle delays the onset of a particular age-related change or pathology does not mean it delays aging, in the same way that antibiotics used to treat opportunistic infections in patients with AIDS, even if they preserve health, are not targeting the ultimate cause of AIDS which is HIV. As such, my aim in this essay is to discuss interventions in the context of whether they can delay the aging process rather than one of its many consequences.

There are also ways of living longer. Following all that motherly advice like regular exercise and adequate nutrition can make you live longer (Holloszy, 2000), as discussed further below, and any therapy that ameliorates mortality from a specific disease will increase longevity. Still, living longer does not necessarily mean that the fundamental process of aging has been slowed down. Living a healthy life will lower your mortality across the entire lifespan, even if there is no impact on aging and age-related changes. For example, longevity increased roughly 50% in the past century and yet there is no evidence people age slower; we live longer now mostly because deaths caused by infectious diseases have gone down (Hayflick, 1994, pp. 84-88). This important distinction holds true for animal studies. Royal jelly and fish oil can significantly increase the average lifespan of mice (Jolly et al., 2001; Inoue et al., 2003), and yet that does not mean that aging has been delayed by these treatments; all it means is that these nutrients are healthy. Therefore, a great deal of care is necessary when interpreting life-extension studies and there is a lot of controversy in what represents delayed aging.

So how can we determine whether a given intervention delays aging? Based on my definition of aging, a given intervention to be accepted as anti-aging must demonstrate that the onset or pace of multiple age-related changes, including pathologies, is delayed. In addition, while accurately quantifying the rate of aging is impossible, one method to estimate the rate of aging is to calculate the rate at which mortality increases with age and so determining whether a given intervention delays this rate can also help determine if the aging process was delayed (de Magalhaes et al., 2005). Any intervention that fails to meet these criteria cannot be considered as truly anti-aging, even if it extends average lifespan or delays a given age-related change. This debate concerning what anti-aging means is the major source of confusion concerning anti-aging medicine and is often used by companies and even scientists to mislead the public. Certainly, some products pitched as anti-aging may be healthy and/or may soften the effects of aging. For example, a given anti-wrinkle cream may ameliorate one particular effect of aging (wrinkles), but it will not impact on any other aging sign. Importantly, an anti-wrinkle cream will not increase longevity much less delay the mortality acceleration with age and hence its effects on aging will be so superficial that scientifically I do not think it can be considered as anti-aging.

To complicate matters even further, because studying aging in humans is extremely expensive and time-consuming, it is virtually impossible to test whether a given intervention or product delays aging in humans and thus testing whether a product impacts on aging is usually done in animal models. Because animals may or may not be representative of human biology, interpreting the life-extending effects of products in animals must be done with caution. Even studies in animals might be artifacts of particular experimental conditions. For example, one of the largest increases in lifespan (44%) by a product was obtained by feeding worms a synthetic antioxidant called EUK-8 (Melov et al., 2000). Other scientists, however, failed to reproduce these results (Keaney and Gems, 2003), even though EUK-8 was shown to increase antioxidant levels (Keaney et al., 2004), which suggests that possibly very peculiar conditions are necessary for this particular product to increase lifespan.

As detailed elsewhere, senescence.info is not a medical website. It is a website about aging, namely about the whole aging process with a special emphasis on human aging, and thus the following products are interpreted in view of their potential impact on the human aging process as a whole. Hopefully, I can demystify some of hype surrounding these products and, based on scientific evidence, help clarify what they can and cannot do. In the same way I find it crucial to highlight progress and potential in aging research and the possibility (no matter how distant and difficult) of curing aging, it is equally important to fight false publicity, particularly in a field with such a fraudulent past like aging research. Given the numerous products in the recent past thought to be useful and later proven to have negative side-effects (e.g., fen-phen and ephedra), and the lack of clinical studies for most anti-aging products, discussing the scientific evidence is vital.

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Anti-Aging Medicine: Current Therapies from the Science of ...

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The 23rd Annual World Congress on Anti-Aging Medicine

We offer a multitude of medical services as part of our preventative medical treatment focused on regaining and maintaining optimal health, vitality and vigor. Improving your metabolic function and optimizing hormones like testosterone, estrogen, progesterone, DHEA and others, can give you a better opportunity for a healthy and vigorous life.

Our goal is for you to be disease resistant, mentally sharp, and physically fit. So called Anti Aging Medicine may not be able to reverse aging, or extend longevity, however our hormone replacement treatments are able to address age related physical, mental and sexual problems and enhance your quality of life.

Our resident specialist, Dr. Lionel Bissoon (DO) has been practicing for over 20 years. Author of the book The Cellulite Cure, Dr. Bissoon is a highly skilled physician with a wide range of medical knowledge. He has received training in multiple fields of medicine and draws upon his various medical field of knowledge to synthesize a comprehensive approach to treating all his patients.

Our highly specialized Physicians will individually tailor a comprehensive program that may include bio-identical hormone replacement therapy. Diet and exercise regimens will be recommended along with a specialized vitamin supplementation programs designed to replenish the body with nutrients typically lacking in the modern diet, and required for optimum health.

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Anti Aging Medicine, Skin Tightening & Stem Cell treatment ...

California Age Management Institute is the first and foremost medical provider of anti-aging / age management medicine dedicated to the proposition that:

age is a state of mind ... aging is a manageable condition

As pioneers in the rapidly expanding anti aging field, we are increasingly imitated -- but never duplicated. .

We have a full spectrum of time-tested offerings including relief from the dysfunctions of menopause and andropause. We are leaders in the use of bio-identical hormone replacement therapy. And we offer more ... management of complex cardiovascular and lipid problems, diabetes, and challenging thyroid problems.

Ask us about CIMT -- carotid intimal medial thickness testing -- our newest offering as the only center in the San Francisco Bay Area to offer this cutting-edge imaging service. Looking for the earliest and most treatable stage of vascular dysfunction and disease.

We look forward to meeting with you very soon..

It's now up to you ... a friendly and personal patient coordinator will answer your call at 408-358-8855..

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anti-aging medicine from California Age Management Institute

Life extension science, also known as anti-aging medicine, indefinite life extension, experimental gerontology, and biomedical gerontology, is the study of slowing down or reversing the processes of aging to extend both the maximum and average lifespan. Some researchers in this area, and "life extensionists", "immortalists" or "longevists" (those who wish to achieve longer lives themselves), believe that future breakthroughs in tissue rejuvenation, stem cells, regenerative medicine, molecular repair, pharmaceuticals, and organ replacement (such as with artificial organs or xenotransplantations) will eventually enable humans to have indefinite lifespans (agerasia[1]) through complete rejuvenation to a healthy youthful condition.

The sale of putative anti-aging products such as nutrition, physical fitness, skin care, hormone replacements, vitamins, supplements and herbs is a lucrative global industry, with the US market generating about $50billion of revenue each year.[2] Some medical experts state that the use of such products has not been proven to affect the aging process and many claims regarding the efficacy of these marketed products have been roundly criticized by medical experts, including the American Medical Association.[2][3][4][5][6]

However, it has not been shown that the goal of indefinite human lifespans itself is necessarily unfeasible; some animals such as hydra, planarian flatworms, and certain sponges, corals, and jellyfish do not die of old age and exhibit potential immortality.[7][8][9][10] The ethical ramifications of life extension are debated by bioethicists.

Life extension is a controversial topic due to fear of overpopulation and possible effects on society.[11] Religious people are no more likely to oppose life extension than the unaffiliated,[12] though some variation exists between religious denominations. Biogerontologist Aubrey De Grey counters the overpopulation critique by pointing out that the therapy could postpone or eliminate menopause, allowing women to space out their pregnancies over more years and thus decreasing the yearly population growth rate.[13] Moreover, the philosopher and futurist Max More argues that, given the fact the worldwide population growth rate is slowing down and is projected to eventually stabilize and begin falling, superlongevity would be unlikely to contribute to overpopulation.[11]

A Spring 2013 Pew Research poll in the United States found that 38% of Americans would want life extension treatments, and 56% would reject it. However, it also found that 68% believed most people would want it and that only 4% consider an "ideal lifespan" to be more than 120 years. The median "ideal lifespan" was 91 years of age and the majority of the public (63%) viewed medical advances aimed at prolonging life as generally good. 41% of Americans believed that radical life extension would be good for society, while 51% said they believed it would be bad for society.[12] One possibility for why 56% of Americans claim they would reject life extension treatments may be due to the cultural perception that living longer would result in a longer period of decrepitude, and that the elderly in our current society are unhealthy.[14]

During the process of aging, an organism accumulates damage to its macromolecules, cells, tissues, and organs. Specifically, aging is characterized as and thought to be caused by "genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication."[15]Oxidation damage to cellular contents caused by free radicals is believed to contribute to aging as well.[16][16][17]

The longest a human has ever been proven to live is 122 years, the case of Jeanne Calment who was born in 1875 and died in 1997, whereas the maximum lifespan of a wildtype mouse, commonly used as a model in research on aging, is about three years.[18] Genetic differences between humans and mice that may account for these different aging rates include differences in efficiency of DNA repair, antioxidant defenses, energy metabolism, proteostasis maintenance, and recycling mechanisms such as autophagy.[19]

Average lifespan in a population is lowered by infant and child mortality, which are frequently linked to infectious diseases or nutrition problems. Later in life, vulnerability to accidents and age-related chronic disease such as cancer or cardiovascular disease play an increasing role in mortality. Extension of expected lifespan can often be achieved by access to improved medical care, vaccinations, good diet, exercise and avoidance of hazards such as smoking.

Maximum lifespan is determined by the rate of aging for a species inherent in its genes and by environmental factors. Widely recognized methods of extending maximum lifespan in model organisms such as nematodes, fruit flies, and mice include caloric restriction, gene manipulation, and administration of pharmaceuticals.[20] Another technique uses evolutionary pressures such as breeding from only older members or altering levels of extrinsic mortality.[21][22]

Theoretically, extension of maximum lifespan in humans could be achieved by reducing the rate of aging damage by periodic replacement of damaged tissues, molecular repair or rejuvenation of deteriorated cells and tissues, reversal of harmful epigenetic changes, or the enhancement of telomerase enzyme activity.[23][24]

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Life extension - Wikipedia, the free encyclopedia