Some marijuana advocates believe that marijuana laws are outpacing science, as several states like Massachusetts are legalizing the drug for medical use. Scientists are grappling with the lack of information on the effectiveness of using marijuana as a medicine and its effect on the brain and health in general. Legalization of marijuana is facing a disconnect against both state and federal governments as marijuana is classified as a controlled substance. This article explores medical and recreational marijuana and its effects on health. The MIND Program Marijuana Investigations for Neuroscientific Discovery

What scientists know about marijuana are from studies from chronic recreational users, but very little is known about the effects on casual users. There is a big difference between the medical and recreational use of marijuana, as medical users usually do not want higher levels of the THC drug found in marijuana. Recreational users are more inclined to enjoy high concentrations of the drug and concerns about the youngest users are well founded. However the potential medical effects of cannabis cannot be underestimated, but sound clinical research in this field is scarce. This has given rise to a trial called the MIND program developed at the McLean Hospital.

In the MIND program's first study, a group of patients certified for medical marijuana were put through a trial. For three months patients were tested for how marijuana affected their conditions ranging from chronic pain, PTSD, anxiety, and sleep disorders. Many individuals felt a relief in symptoms, better sleep, and mood levels. The researchers also found that patients performed better cognitively with improved executive functions and a reduced need for painkillers.

Youth at Risk of Serious Cognitive Impairment

In a recent study on medical marijuana, striking differences were found in recreational users, especially in cognitive performance in executive functions of the brain. The biggest differences occur with adolescents who regularly used marijuana before age 16. This can seriously and irreversibly alter the brain structure and functions in youths.

For recreational users of marijuana, the drug THC is responsible for altering individuals state of being. But for medical use, the THC is lower in dose and compounds like CBD are responsible for relief. One possible reason that medical marijuana users don't experience any cognitive impairments is due to the average age of 49, well above the more vulnerable ages from adolescence to 20.

Researchers have hope for some patients who are dependent on opioid drugs. The idea is to supplement their treatment with cannabinoid-based products while reducing or even eliminating opioids. Some people are expressing concern over the ethics of replacing one addiction for another.

More Studies Needed on Medical Marijuana Use

Experts are expressing the need for more studies on medical marijuana. Given the federal government's laws on marijuana as a controlled substance, researchers are finding it difficult to legally conduct trials of cannabinoid substances. Scientists need to understand what effects marijuana has on people's cognitive functions. Not being able to do clinical trial studies limits the researcher's abilities to find out if medical marijuana works for their patients.

As legalization looms in Massachusetts, it's important to inform the public to keep an open dialog with kids and young adults about marijuana use at a young age. Preaching abstinence may make kids more likely to try recreational marijuana the worst thing parents want to happen as young brains are neurodevelopmentally immature to the negative impact of marijuana. Providing the truth on cannabis, and letting the public make informed decisions regardless of medical or recreational use, may be the best approach.

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Has Marijuana Policy Outpaced Science? | Worldhealth.net Anti ... - Anti Aging News

Question: What is carboxytherapy?

Answer: Carboxytherapy is a treatment that uses carbon dioxide in controlled doses to treat a number of aesthetic conditions. It was first discovered in 1946 in France, when physicians noticed that patients with circulation problems improved in the carbon dioxide-rich thermal waters of Royat.

The indications for this therapy have extended since then from treating medical problems to its application in aesthetic medicine as an effective treatment for stretch marks, cellulite, localized fat deposits, scars, hair loss, improvement of skin laxity, wrinkles and dark circle under the eyes.

Carbon dioxide is a naturally occurring gas that the body produces as a byproduct of respiration and cellular metabolism. As such, it is safe to use; in fact, it is used extensively in medicine every day, such as in colonoscopies and laparoscopic surgery. Carbone dioxide has no toxicity even in elevated doses.

As a result of aging, we may have decreased blood flow and oxygen delivery to the tissues. When carbon dioxide is injected into the treated area, your body detects a lack of oxygen in that area and reacts by dilating your capillaries, thereby improving blood flow and oxygen delivery. This stimulates fat cell and scar tissue breakdown, while simultaneously increasing collagen production. The procedure uses a small needle to infuse the carbon dioxide gas under the skin. It usually requires a series of treatments for optimal results and there is no downtime. For more information visitwww.drdadurian.com or call 561-655-6325 for a complimentary consultation.

Daniela Dadurian, M.D., specializes in anti-aging medicine and is an expert in non-surgical body-contouring techniques. She received her medical degree from the University of Miami School of Medicine and has traveled the world researching the safest and latest technologies on the market.

______________________________________

MD Beauty Labs Medical Spa and Wellness Center

320 S. Quadrille Blvd. West Palm Beach

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Learn more about carboxytherapy - Palm Beach Post

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Heartiest Congratulations to Our Royal Patron HIS MAJESTY THE YANG DI-PERTUAN AGONG XV SULTAN MUHAMMAD V D.K., D.M.N, D.K.(Selangor), D.K.(Negeri Sembilan), D.K. (Johor), D.K.(Perak), D.K.(Perlis), D.K(Kedah), D.K.(Terengganu), S.P.M.K., S.J.M.K, S.P.K.K, S.P.S.K.

2017 WAAARNEM

Preliminary Announcement

2017 WAAARNEM

Sponsorship Prospectus and Sponsorship Booking Form

Announcing SAAARMMS new platform

The INAUGURAL WORLD CONGRESS IN ANTI-AGING, AESTHETIC, REGENERATIVE , NUTRITIONAL AND EXERCISE MEDICINE (WAAARNEM) will be held in conjunction with 14th Malaysian Conference and Exhibition & 7th International Congress and Exhibition on Anti-Aging, Aesthetic and Regenerative Medicine Dates: April 28 30, 2017 Venue: Sheraton Imperial Kuala Lumpur

Other Upcoming Events

Advanced Course in Nutritional Medicine 11-12th February, 2017 Professional Certificate in Aesthetic Medical Practice (PCAMP) Conjoint Examination conducted by SAAARMM February 12, 2017

You may email info@saaarmm.org or contact the SAAARMM Secretariat between 9.00 am and 4.00pm Mondays Fridays (Tel Nos. 03-40410092 or 03-40416336) for enquiries/programme, etc. Programme to be announced.

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Dr. LightCosmetic surgery and hormone replacement address the same issue from different vantage points. As such, bioidentical hormone replacement therapy, or BHRT, is a powerful tool that should be incorporated into all successful cosmetic practices, according to Kevin Light, DO, MBA, a cosmetic surgeon and age management specialist in Dallas, Texas. Dr. Light presented Bioidentical Hormone Replacement Therapy and the Cosmetic Surgery Practice yesterday at the American Academy of Cosmetic Surgerys (AACSs) 2017 annual scientific meeting in San Diego, Calif. Dr. Light, author of the book OutSmart Aging, tells Cosmetic Surgery Times that, from a cosmetic perspective, aging negatively impacts the skin, with thinning, wrinkling, age spots and pigmentation, as well as loss of elasticity, resiliency and glow. Cosmetic aging results in soft tissue volume loss, in the face, breast and abdomen. It also results in bone loss, or shrinkage of the skull and mandible; hair loss, weight gain and fat redistribution. Hormone loss causes impaired wound healing and immune function, which can impact cosmetic surgery patients. Hormone loss also results in quality of life issues, from energy and sleep, to concentration, memory, libido and sexual function, he says. BHRT can halt or reverse all of this. This is no longer 'magic' and is well documented in the literature, Dr. Light says. From a business perspective, bioidentical hormone therapy is a $15 billion business and trending positively, Dr. Light says. Patients are aware of it and are demanding it. Several early adopter plastic and cosmetic surgeons around the country already offer it, Dr. Light says. BHRT is a powerful adjunct to age management and enhances patient 'stickiness' for the cosmetic surgery practice. The business model is easy and can be delegated to others. It presents incredible cross-sell opportunities.

NEXT: Dr. Lights Tips for Getting Started

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BHRT: A match made in anti-aging - ModernMedicine

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Recently, I started taking an online class through Coursera called Understanding Medical Research: Your Facebook is Wrong because it was free and I wanted to take a fun class to fill the time before Summer Session I. As I started listening to the lectures, I became aware of just how prevalent false information really is.

While some of these claims are more egregious, such as the president of the United States suggesting that injecting disinfectant into your lungs can stop the spread of the coronavirus, other claims are more hidden.

Today, about one in four adults in the U.S. gets at least some portion of their daily news from social media, and we are constantly bombarded with headlines promising a miracle cure for certain ailments, or advertising products that promote anti-aging cream or fast weight loss, which often cite various scientific studies to support their claims.

However, according to a study done this year, only a small percentage of fake-news claims ever get fact checked by social media platforms. While Im not suggesting that every study is false, it is true that studies often manipulate information to make their products sound better, which can make it difficult to discern fact from fiction.

Fortunately, social media platforms including Facebook and YouTube have taken measures to eliminate the spread of fake news; some of these platforms are providing information panels, which give more details about where the information comes from. However, sometimes it can seem much easier to skip past this extra information, especially when the headlines seem credible or plausible.

F. Perry Wilson, the instructor of the online course I previously mentioned, uses an example of the drug Lipitor, a heart medication, to illustrate the problem with taking the claims in headlines and advertisements at face value. According to the advertisement for Lipitor, the manufacturer claimed the drug had a 36% success rate. However, after absolute versus relative risk was taken into account, the actual data revealed that the drug only prevented one death out of every 100 people.

While this might seem abstract or unrelatedafter all, college students are usually not the intended audience for heart medicationstudies like these are prevalent across social media, and are often buried beneath medical jargon and statistics that have been skewed or misrepresented.

Even though it might sound tedious or unnecessary, learning terms such as relative and absolute risk as well as having a basic knowledge of statistics and medical terminology could help disseminate the spread of false information and could potentially save your life or someone elses life.

In addition to learning the terminology needed to navigate an article, it is also important to thoroughly read an article before accepting it is true, as headlines can often be misleading. Recently, hydroxychloroquine, an antimalarial drug, has received a lot of attention in the media for being a potential cure for coronavirus. According to the Association of American Physicians and Surgeons, hydroxychloroquine has about a 90% chance of helping COVID-19 patients. While I am not necessarily suggesting this study is wrong, it was conducted with a sample size of 2,333 patients, which is a relatively small sample size considering that currently over 4.2 million people across six continents have contracted COVID-19.

It is also important to double-check the headlines as well as the study itself. While I was doing research for this column, I saw an article abstract from The New England Journal of Medicine which claimed there is robust evidence to support the use of hydroxychloroquine on COVID-19 patients; however, when I read the abstract a second time, I saw that it actually said Hydroxychloroquine has been widely administered to patients with COVID-19 without robust evidence supporting its use.

While it is near impossible to completely eliminate fake or misleading information from our daily social media consumption, the ability to think critically can help us sort fact from fiction. While many of these claims may be harmless, some might have a more serious impact, and it is up to us as students, as well as citizens, to learn how to recognize false information, no matter what our first impressions might lead us to believe.

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OPINION: Beyond the headlines: learning to recognize fake news is as important as ever - N.C. State University Technician Online

A growing body of evidence is emerging in support of medical nutrition therapy as a way of reducing severity and incidence of dermatologic diseases, according to recent findings.

Medical nutrition therapy (MNT) for the treatment of dermatological conditions is an evolving science that involves collaboration between a dermatologist and registered dietitian to offer the patient the most scientifically sound nutrition/dietary advice to potentially quell symptoms of chronic disease like acne, eczema and psoriasis, Martina M. Cartwright, PhD, RD, of the department of nutritional sciences at the University of Arizona, Tucson, told Healio Dermatology. MNT plays a role in wound healing and may be used to reduce the signs of skin aging. This is the first article to offer a roadmap to applying MNT to a variety of skin conditions.

Cartwright added that diet and nutrition are not cures for skin ailments, but they may help alleviate symptoms.

In the current review article, the researchers noted that research has advanced beyond the role of individual nutrients, supplements and foods in disease to MNT, which they describe as a multidisciplinary adjuvant form of medical practice.

According to the researchers, cause and effect is rarely observed with diet/nutrition and dermatologic conditions. Rather, associations some of them compelling have been drawn between diet and outcomes including disease severity and the number of conditions experienced by a patient.

The review article covers a cross-section of food groups and supplements, from various carbohydrates, proteins and fats, to linoleic acids and eicosapentaenoic acids (EPAs), to simple and complex sugars, to vitamins ranging from beta-carotene to zinc. Charts detail how excesses or deficiencies of these foods and supplements can affect overall and dermatologic health.

Disease-specific information is also included, with dietary advice for acne, atopic dermatitis, melanoma, psoriasis, rosacea and wound care included.

Looking closer at specific associations, the researchers observed a link between high glycemic index foods and acne. They reported that immunoglobulin E (IgE)-related allergies were associated with AD, and that weight loss and improved waist circumference may improve psoriasis.

Eliminating hot and spicy foods may benefit patients with rosacea, whereas increased protein intake may speed up the healing process for wounds, they wrote.

Regarding melanoma, an anti-inflammatory, nutrient dense diet is recommended.

Cartwright noted that over 25 years of being a dietitian, presentations at dermatology conferences have focused largely on linking diet or nutrition with worsening of skin disorders, but rarely have discussions focused on improvement or practical how-to advice for the patient. This is where MNT comes in, she said. It is a collaborative approach between the dermatology physician and registered dietitian to tackle skin disorders from a scientific and personalized medicine prospective, using the latest evidence-based medicine and counseling strategies that foster lasting nutritional changes and produce meaningful clinical outcomes.

Nutritional advice without practical counseling usually goes nowhere with the patient, she added. by Rob Volansky

Disclosure: Cartwright reports she is a speaker for Abbott Nutrition.

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Medical nutrition therapy shows positive benefits in dermatologic conditions - Healio

The Watson supercomputer, created by technology company IBM, uses the power of artificial intelligence (AI) in ways that benefit mankind. In 2011, the world was introduced to the potential of AI when Watson won the title of world champion on the popular game show Jeopardy! In 2011.

Since then, Watsons developers have focused on customizing the AI for medical use. Programmers have integrated thousands of patient records, scores of medical texts, and all the content in the PubMed and Medline databases into Watsons working memory. In all, the AI has consumed 2 million pages of text that represent over 600,000 pieces of medical evidence, 25,000 training cases, and 14,700 hours of clinical training.

The Benefits of Using AI in Medical Diagnoses

AI programs, like Watson, are gaining importance in information-heavy fields, like medicine. The supercomputer is able to store more information than a human brain and can access the information more quickly. In addition, a computer-generated diagnosis is based on evidence and established fact, while human doctors may be swayed by cognitive biases or confidence issues.

The Watson AI uses an interface that allows users to speak to it in a natural way. The machine is able to gather and analyze information from patients and compare it to stored information. Based on this inquiry, the AI can then make an accurate diagnosis.

More than just comparing bits of information, the Watson supercomputer is able to form hypotheses independently. In a process that is similar to the way humans learn, the machine can then test and evaluate its own hypotheses, disregarding what doesnt work and adjusting for error.

In 2011, McAfee wrote about the advantages of using AI for medical purposes. AI diagnoses are based on the complete published body of medical knowledge, making it the most up-to-date medical resource. Diagnostic programs are also accurate, consistent, cost very little to operate, and can be used anywhere in the world.

AI: The Future in Medical Care

When using AI for diagnostics, a physician describes symptoms and other contributing factors to the program. The computer then mines patient history and its own databases, and along with test results and other pieces of medically relevant data, creates a hypothesis. The hypothesis is tested against its information on treatments, hospital records, and published studies and research. Once satisfied that the hypothesis is valid, Watson can then give a customized treatment plan for the patient.

While Watson has incredible capacity, only a few companies are taking advantage of it. MD Anderson Cancer Center uses AI to develop treatment plans for leukemia patients. The medical company WellPoint uses Watson-based software to allow patients to evaluate their doctors treatment plans.

Currently, the Watson AI is not able to fully use all of the information it has access to. Developers are working with the program to help it develop the mental agility and versatility of thought that makes human doctors so effective.

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IBM's Watson - Best Doctor In The World? - Anti Aging News

A4M has for the past 25 years shown the ability through vision and technology to make American medical care great once again. The time has come for a major overhaul of the American healthcare system. "While Obamacare had some noble intentions, Obamacare and politicians have driven medicine into a constant state of disarray. Its time for medical leaders such as the A4M to voice their opinion," asserts Dr. Ronald Klatz.

Dr. Ronald Klatz, M.D., D.O., physician-founder of the American Academy of Ant-Aging Medicine and patent holder of over 30 medical innovations stated, "Physicians must resume control of patient care. Today the insurance company rep has more influence than a doctor. Thats a sad statement. It is necessary to have a plan that restores authority to highly experienced, regulated and educated medical professionals. We should focus on effective, preventative healthcare to extend quality of life and increase longevity, and simply bring back common sense to medicine."

The following 10-point, low-cost, high-tech healthcare, wellness, and anti-aging plan has the potential to save American tax payers over one trillion dollars over the next seven years:

Point One: Point of Care (POC) Laboratory Testing. Defined as testing at/near the site of patient care. The goal of POCT is to allow more rapid and effective diagnosis and triage, leading to improved patient outcomes, reduced morbidity and mortality, and slashed costs.

Point Two: Biomarkers of Aging and Health Measurement. Billions of health care dollars are wasted on diseases that can be detected and treated early or prior to occurrence: heart disease and stroke, cancer, and Type 2 diabetes.

Point Three: Free Biannual Comprehensive Metabolic Testing. These tests may slash Type 2 diabetes and metabolic syndrome costs by 20%. This is significant given that Metabolic Syndrome is a primary cause of cardiovascular disease (CVD).

Point Four: 24/7 Telemedicine Consultation Access. The improvements generated from the use of telemedicine are vast. Telemedicine provides access to medical professionals for residents of remote areas and people with limited mobility, unclogs emergency rooms from non-emergency patients, and creates jobs for people who are only able to work via telecommuting.

Point Five: Aging Intervention Drugs. Six major diseases are having an enormous impact on the 65+ population: chronic lung disease, ischemic heart disease, stroke, lung cancer, pneumonia, and gastrointestinal illness.

Point Six: Stem Cells and Nanotechnology Access. These biomedical technologies offer exciting potential for significant improvement and/or cures for previously incurable conditions, such as stroke, cancers, Alzheimer's disease, Parkinson's disease, ALS, paraplegia, and other crippling neuromuscular disorders.

Point Seven: Personalized Genetic Testing and Nutrigenomics. Making these resources widely accessible allows for prospective identification of major disease processes including heart disease, cancer, diabetes, Alzheimer's disease, etc., such that appropriate interventions may be deployed at the earliest stage possible, providing the best chance for recovery and less invasive and more cost-effective treatment options.

Point Eight: Free/Subsidized Access to Gym, Spa, Metabolic Detoxification, and Physical Rehabilitation Facilities. Without question, obesity is costing the United States billions upon billions of dollars to combat all of its resulting diseases and conditions.

Point Nine: Online Electronic Database on Aging Intervention & Free Medical Education Resources. By promoting practitioner and patient education, an improved paradigm is created in which physicians keep current on new technologies and patients questions and form a collaborative relationship with their medical caretakers. This increased education on both sides of the healthcare relationship will provide more accountability and communication.

Point Ten: World Center for Anti-Aging Medicine. A center of excellence to extend quality of life into the later years of the average lifespan is necessary for reducing costs and improving living. One centralized research facility dedicated to this specific mission is necessary to focus adequate attention on this vital scientific arena.

While prior administrations have failed to properly consider the value of shifting from a "disease based" healthcare model to an advanced preventative based, cost-saving platform, the new administration has an opportunity to change course. Elected leadership should implement this comprehensive plan immediately to reduce skyrocketing costs and improve the quality of all our lives. The new Health and Human Services (HHS) administration must help Americans get true, proven preventative care and encourage healthier lifestyles. This is the time for real solutions.

As Dr. Klatz states, "We already have the technology to live a quality, healthy, productive, youthful 100 years- plus. Now lets do it!" Please forward to your representative in Washington.

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Let's Make American Medicine Great Again - Anti Aging News

Posted on March 2, 2017, 6 a.m. in Biotechnology Drug Delivery Technology

Researchers develop the first DNA computer capable of pinpointing several antibodies in the blood and carrying through resultant calculations.

A team of researchers has developed an intelligent DNA computer that can enable controlled drug delivery into the bloodstream. The team, from Eindhoven University of Technology in the Netherlands, believes this new method will lead to the development of smart drugs that more effectively treat autoimmune diseases like rheumatoid arthritis and Crohn's disease. The team, led by Professor of Biochemical Chemistry Maarten Merkx, published their findings in the Nature Communications journal.

DNA Computing

DNA computing is a largely experimental field of scientific study. Using a combination of DNA, biochemistry, and molecular biology hardware, researchers seek to use DNA sequencing for data storage and to perform complex calculations.

The goal of this new field is to create nano-computers using DNA instead of mechanical parts. The resulting machines would be able to store immense amounts of data and make complex calculations faster than inorganic equipment. Some scientists believe DNA computers may one day replace silicon-based hardware.

Possible Applications in Medical Treatment

DNA computing methods, due to their organic nature, allow medicines to work more effectively with the bodys natural defenses. Researchers compare the body to a security system with facial recognition. Previous research has focused on creating a machine that is recognized by the body, similar to the way a security system would recognize an authorized person.

Professor Merkxs method adds the ability to recognize the presence of antibodies. The identification and measurement of antibodies is a crucial step in diagnosing and treating disease. Antibody levels are also a factor when calculating the dosage of therapeutic drugs.

With DNA nano-computers able to detect and measure antibodies while performing complex analyses, researchers are hopeful machines can be programmed to carry out actions in response to certain measurements. Merkxs team successfully used DNA computing to control the activity of enzymes. The professor believes it is possible to apply this technique to therapeutic antibodies. This should result in better absorption of therapeutic substances. When used as a delivery system, these computers will be able to decide how much medicine to release into the bloodstream, based on the antibodies in the bloodstream.

Future Applications in the Treatment of Chronic Disease

Researchers are working on ways to use the technology in the fight against chronic diseases like rheumatoid arthritis and Crohns Disease. These conditions are often treated with the same drugs. The dosage is dependent on the condition it is meant to treat. Smart drugs would be able to deliver the most accurately therapeutic dose of medication. This would allow for more effective treatment. It would also reduce the overall cost of treatment and reduce side effects.

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DNA Computer Enables Controlled Drug Delivery - Anti Aging News

(MENAFN Editorial) Hermann Wellness, an anti-aging treatment medical spa with locations in Tampa and St. Petersburg, recently launched its newly redesigned and restructured website at http://doctorhermann.com.

Hermann Wellness, led by Dr. Anne Hermann, M.D., provides the best and most comprehensive aesthetic medicine services in the Tampa Bay area. It is Dr. Hermanns mission to enable each of her patients to achieve optimal health by combining cutting edge technology and the latest research with compassionate medical care. Now, Hermann Wellness offers visitors and patients an updated and redesigned website for an enhanced browsing experience.

The newly designed Hermann Wellness website, found at http://doctorhermann.com, offers users a comprehensive menu with detailed information about each of the more than 50 services that Dr. Hermann has to offer. This interactive site also offers informative videos from Dr. Hermann herself, an online scheduling tool, and reviews from past patients. Overall, the new design and fresh content highlight the true impact that Dr. Hermann and her team can make to improve her patients overall health offering treatments that address overall wellness and beauty from the inside out.

Dr. Hermann has more than 17 years of experience in internal, holistic, and cosmetic medicine. She obtained her Board Certification in Internal Medicine in 2000, then trained as a medical acupuncturist at UCLA Medical School and Professional Hypnologist at the CordInstitute of Hypnosis in 2004. Dr. Hermann also became Board Certified as a Physician Nutrition Specialist in 2004. Since then, she has completed advanced training in botox, dermal fillers, and other cosmetic procedures, and she has continued to grow her expertise within the holistic approach to medicine.

With two locations in Tampa and St. Petersburg, Hermann Wellness is conveniently located for all patients seeking customized care for aesthetic treatments, weight loss services, integrative medicine, and much more. Dr. Hermanns extensive training and experience in aesthetics and weight loss has made Hermann Wellness Tampa Bays leader in cosmetic services and physician assisted weight loss and nutrition.

Anti-aging PRP injections, dermal fillers, and micro-needling skin resurfacing to the Optifast weight loss plan and Detox Diet, Hermann Wellness offers all of the essential services that help patients achieve the health and confidence they have always wanted.

Members of the community or media interested in learning more about Hermann Wellness and its newly designed website are invited to use the following contact information:

NAME: Dr. Anne Hermann, M.D. ADDRESS: 3040 W. Cypress St., Suite 103, Tampa, FL 33609 or 6387 Central Ave, St. Petersburg, FL 33710 PHONE: (813) 902-9559 (Tampa) or (727) 278-3992 (St. Petersburg) WEBSITE: http://doctorhermann.com EMAIL:

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Hermann Wellness of Tampa and St. Petersburg Launches Newly Designed Website - MENAFN.COM

As Trump shakes up the White House, pharma and biotech are on edge. While the media talks about Obamacare, it turns out that Trumps new FDA chief could have a bigger impact on health care and associated markets. The story here is that a company in liberal Northern California may have the most to gain from a Trump FDA.

Mount Tam Biotechnologies (MNTM), named for the highest peak of the Marin Hills, is located on the campus of the nonprofit Buck Institute. The Buck was the worlds first institute founded to research aging. Today, its a leader in the emerging field of geroprotection.

The term geroprotection is replacing life extension among scientists. One reason is that many people associate life extension with pseudosciences and health fads. Many also assume it means prolonging the frailty and suffering that comes at the end of life (think Howard Hughes).

Biogerontologists dont want to extend suffering. Rather, their goal is to protect us from the medical and financial effects of aging. They want to extend the healthy portion of our lives (our health spans) for as long as possible. This is known as morbidity compression.

A few decades ago, this goal was science fiction. Most scientists did not think that simple drugs could extend health spans. Thats no longer the case.

Longer Health Spans Are Possible

The cause of this change in attitude is simple. It is the enormous body of research regardingthe mTOR geneand the mTOR pathways.

The Buck Institute has played a major role in that research, acquiring significant legal rights to the drug rapamycin. This drug extends health spans in animals via the mTOR gene pathways. Now, those rights are licensed to Mount Tam.

Studies show that mice given rapamycin in their diets live about 15% longer than untreated mice. Lets put those results into perspective. If we were to put an end to atherosclerosis and cancer in humans, it would extend lifespans by less than 10%.

Even when rapamycin is given to mice that are old, the animals are rejuvenated. They exhibit the traits of younger animals. They show slightly less (but still significant) increases in health spans as the mice that were treated earlier in life.

The Company That Has the Cure for Aging

Increasingly, gerontologists think that age-related diseases are caused by the breakdown of our biological control systems. The immune system is one such control system and it can be modified using rapamycin . This implies that we could treat other systems to prevent or delay age-related disease.

In spite of this, medicine is still based on the old disease model. Doctors wait for a disease to appear and then treat it. Regulators approve drugs to help treat full-blown diseases. This needs to change.

But the move from a disease cure to a disease prevention model is quite complex. One reason is that proving a drugpreventsserious disease is much harder than showing improvement.

Investors have been even slower to catch on to this new paradigm. Thats why the biotech executives that I know think its financial suicide to suggest that a drug has anti-aging properties.

This may be the reason that Mount Tam is silent about the geroprotective impacts of its rapalogs, despite the massive body of research. Rapalogs are variations (or analogs) of the rapamycin molecule genetically engineered to reduce unwanted side effects.Based on its patent application, it seems Mount Tam has produced a rapamycin analog without side effects that would deem it unsafe to regulators.

We have reason to think that both Mount Tam rapalogs would be geroprotective. Rapamycin has, in fact, been used off-label to treat the autoimmune disorder lupus with success.

Mount Tam executives, including the former CEO of the Buck Institute Brian Kennedy, PhD, are not promoting geroprotection as a possible application of its platform. You can imagine that this must be hard for someone who has spent his scientific career pursing anti-aging therapies.

Instead, Mount Tams drug candidates are moving forward aimed at systemic lupus erythematosus and cancer. This makes sense because investors know about these diseases and the potential payoffs.

But President Trump just might change things.

Trumps FDA May Support Geroprotection

One of Trumps leading candidates for FDA chief is Jim ONeill. He has stated that he is committed to an accelerated approval process for geroprotectors.

Another candidate, Joseph Gulfo, supports the approval of drugs based on biomarkers instead of actual lifespan data. In other words, a safe drug that makes you medically younger according to blood and other tests could be approved.

Less is known about a third candidate, Dr. Scott Gottlieb, but he does support FDA reform as well.

In the end, Trumps views on drug approval reform are likely to be more important than those of any FDA chief. And Trump has clearly been listening to billionaire advisor and life-extension advocate Peter Thiel. Thiel believes, as I do, that the only way to fix our medical system is to keep people healthier longer.

This puts Mount Tam in a unique position. Recently, the company signed an agreement with the Buck to license all applications of rapamycin analogs. This includes geroprotection. And behind the scenes, the company seems to be preparing for an FDA change that would support geroprotection. (CEO Richard Marshak has confirmed this to me.) You can read more about Mount Tam and its research in Tech Digest. (subscribe here for free.)

There are other geroprotectors in development, but rapamycin enjoys distinct scientific respect because of the mTOR research.

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This Company With Anti-Aging Drug Is Secretly Preparing For Trump's New FDA - Newsmax

Recent research proves that vitamin D guards against colds, the flu and other respiratory illnesses. A daily dose of vitamin D supplements is especially helpful in the quest to fend off sickness. However, even a weekly dose of vitamin D will help in the prevention of colds and the flu. Those who are deficient in vitamin D will especially benefit from a regular dose of this incredibly helpful vitamin. Vitamin D is currently prescribed by physicians for an array of ailments.

Details of the Global Collaborative Study

A team of researchers from around the world determined vitamin D supplements combat the onset of numerous respiratory diseases. Carlos Camargo from Massachusetts General Hospital's Department of Emergency Medicine served as the study's senior author. The research was funded through a grant provided by the United Kingdom's National Institute of Health Research. The worldwide collaborative study confirms that vitamin D supplements help ward off acute respiratory infections.

The study consisted of a meta-analysis of 25 randomized trials with over 11,000 participants. The study's details and results were recently published on the web in The BMJ. It is widely known that vitamin D is vital for muscle and bone health. However, it was unclear as to whether vitamin D played a critically important role in combating acute respiratory infections. Such infections result in millions of hospital visits and deaths across the world each year. Clearing up Conflicting Data

A handful of observational studies that monitored patients across time without implementing a specific treatment had linked low levels of vitamin D to a higher susceptibility of acute respiratory infections. Several clinical trials have also been conducted to study vitamin D supplements' protective ability. Some of these studies determined the vitamin really does provide a protective quality. However, some studies showed that it does not have any protective effect. Meta-analyses performed of these clinical trials aggregated information from numerous studies that have differing designs and/or participant qualifications produced conflicting results.

The global research team referenced above cleared up these conflicting results. Queen Mary University of London's Adrian Martineau led the team. He performed a data meta-analysis of individual participants from over a dozen nations. Participants hailed from the United Kingdom, the United States, Canada and beyond. Prior meta-analyses pit average data from subjects in each study. Alternatively, individualized data meta-analysis distinguishes data from each participant, generating what is considered as a higher-resolution analysis of information across all studies.

The Results

It was determined that weekly and daily vitamin D supplements provided the optimal benefit for those who suffered from a severe vitamin D deficiency. This deficiency is defined as a blood level with 10 mg/dl or less. Vitamin D supplementation reduced the odds of a respiratory infection by one-half for such individuals suffering from a vitamin D deficiency. The study also found that every single participant enjoyed at least a minor benefit from consuming vitamin D supplements on a regular basis. It is worth noting that consuming occasionally high doses of the vitamin did not generate extensive benefits.

The hope is that people will ramp up their consumption of vitamin D supplements to reduce the risk of colds, the flu, and other respiratory maladies. This course of preventative action would prove especially helpful for those who are vitamin D deficient. Such supplementation would reduce the number of emergency department visits, which currently number in the millions. As a result, the health system would be less burdened. Furthermore, the study's findings might inspire food manufacturers to fortify foods with vitamin D. Such a measure would prove especially beneficial to those who are deficient in vitamin D.

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Confirmed: Vitamin D Protects Against Colds and Flu - Worldhealth.net - Anti Aging News

Posted on Feb. 23, 2017, 6 a.m. in Stem Cell Research Immune System Stem Cell

Autologous hematopoietic stem cell transplantation halted progression of Multiple Sclerosis for 5 years in 46% of patients.

Recent research indicates that the transplant of autologous hematopoietic stem cells (AHSCT) is an excellent treatment for multiple sclerosis. It has been determined that the procedure stops disease progression for half a decade in nearly 50 percent of multiple sclerosis patients.

About the Study

The study was spearheaded by Dr. Paolo Muraro from the Imperial College London's Department of Medicine. Dr. Muraro and his colleagues revealed their findings through JAMA Neurology. These results were released on the heels of a separate study that found the success of a similar treatment in patients suffering from relapsing-remitting multiple sclerosis (RRMS). Dr. Muraro and his research team are quick to point out that additional trials are necessary to gauge the efficacy and safety of AHSCT. It is important to note that some patients perished within the first 100 days of treatment.

About AHSCT

AHSCT involves the harvesting of a patient's own stem cells. The patient is subjected to a powerful dose of chemotherapy to destroy any diseased cells. The next step is the return of harvested stem cells to the patient's blood. The goal is to restart the production of normal blood cells.

In layman's terms, AHSCT is best understood as a resetting of the body's immune system. Though it was already known that this style of treatment resets the immune system and poses certain risks, the length of its benefits was not fully understood. We now have a better picture of these benefits. AHSCT Results

The research team studied data from over two dozen treatment centers in 13 countries. They pinpointed 281 patients who suffered from multiple sclerosis and underwent AHSCT from 1995 to 2006. Exactly 78 percent of these patients had a progressive form of multiple sclerosis. The team made use of the Expanded Disability Status Scale (EDSS) to analyze patients' survival after five years of treatment as well as improvements in their multiple sclerosis symptoms. A whopping 46 percent of these patients enjoyed zero disease progression in the five years following treatment. Those with RRMS, characterized by flare-ups (inflammatory attacks) and periods of remission enjoyed the optimal outcomes.

An amazing 73 percent of these patients did not endure worsening of symptoms in the 5 years following AHSCT. Some patients also experienced minor improvements in their multiple sclerosis symptoms following AHSCT. Those with progressive multiple sclerosis enjoyed a rise in EDSS score by 0.14 in the year after treatment. Those with RRMS experienced an EDSS score increase of 0.76. Those of a younger age, minimal immunotherapies before AHSCT and a comparably lower EDSS score also displayed improved outcomes with AHSCT. Treatment Risk

The findings described above clearly show promise for the AHSCT use in individuals who suffer from multiple sclerosis. The research team would like to make it perfectly clear that some patients died in the 100 days following AHSCT. Exactly eight patients perished in this time period. It is assumed that the deaths were related to treatment. AHSCT makes use of aggressive chemotherapy that significantly weakens the immune system and spikes one's risk for infection. Since multiple sclerosis is not a disease that is immediately life-threatening, the risk of death posed by AHSCT must be weighed by all multiple sclerosis patients.

What's next Dr. Muraro is adamant that a follow-up study must be performed that includes a group of multiple sclerosis patients who have not received AHSCT. It is clear that additional studies are required to accurately gauge the efficacy and safety of AHSCT. Ideally, a massive randomized controlled trial of AHSCT will be performed in the coming months.

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Stem Cell Therapy Halts Multiple Sclerosis | Worldhealth.net Anti ... - Anti Aging News

Posted on Feb. 2, 2017, 6 a.m. in Inflammation Genetic Research GI-Digestive

Large Finnish genetic study of over ten million DNA variations reveals new possibilities for treatments of a wide range of inflammatory diseases.

A study conducted by Finnish researchers has pinpointed possible new treatments for an array of inflammatory diseases. The research was conducted by a team at the University of Turku's Research Centre of Applied and Preventive Cardiovascular Medicine. These scientists studied more than 10 million DNA variations and identified new links between inflammation tracers and the human genome. The study determined that there are several new possibilities for the treatments of diseases like coeliac disease, ulcerative colitis, Crohn's disease, atherosclerosis, multiple sclerosis and even some forms of cancer.

An Explanation of Cytokines

Cytokines played a critical role in the above referenced study. These vitally important proteins move throughout the bloodstream to regulate inflammation reactions. Alterations in their mode of operation have been tied to all sorts of inflammatory diseases. The study was centered on an investigation of the connections between 41 unique cytokines as well as growth factors and approximately 10.7 million variations of DNA. The scientists' aim was to identify specific processes at the molecular level that spur a heightened risk for the onset of inflammatory diseases. Gaining an understanding of these processes allows for a more effective treatment of inflammatory diseases.

Scientists found that the medicine daclizumab that was formerly used to treat organ rejection reactions can also serve to treat Crohn's disease and multiple sclerosis. A bump in MIP1b-cytokine activity also functions as a treatment method against Behcet disease and coeliac disease. Additional clinical studies are necessary to verify the observations. Additional Study Details

The data relied upon for the above-referenced study was comprised of long-term research information compiled to span an array of risk factors for heart-related diseases amongst Finns. This data is especially valuable as it is highly unique compared to other data sets used across the globe for similar studies.

Study participants were monitored from childhood all the way to adulthood. The year 1980 was used as a baseline. Over 3,500 people were studied in a cross-sectional manner. Subsequent visits occurred in 1983, 1986, 2001, 2007 and 2011. Surveys pertaining to cardiovascular health were conducted at 5-year intervals from 1972 to 2012 to gauge heart-related risk factors across Finland. All-in-all, nearly 54,000 subjects between the ages of 25 and 74 partook in the surveys.

Evidence Stemming From Human Genetics Hastens Medical Development

Tech developments have allowed for the practice of studies pertaining to genome-wide association for the past 100 years. Such studies took a close look at the millions of variations in DNA and their impact for each of the properties studied. These research efforts have identified more than 100 genomic loci that impact the possibility of ulcerous colitis or Crohn's disease developing. However, the exact molecular process spurring the heightened risk is unclear.

Studies focusing on genome-wide association have been initiated in which response variables molecules are used to mediate the risk of disease within the blood stream. Examples include the use of growth factors and cytokines rather than using the diseases themselves.

The Quest for Safe, Affordable and Effective Medicine

Drug candidates in which evidence from human genetics proves their effectiveness stand a much better chance to be approved within clinical studies. These studies test for safety as well as effectiveness. It is estimated that nearly 800 million dollars will be necessary to develop a market for one medicinal molecule. However, genetics research stands to provide considerable savings in the context of medical development.

Ari V. Ahola-Olli, Peter Wrtz, Aki S. Havulinna, Kristiina Aalto, Niina Pitknen, Terho Lehtimki, Mika Khnen, Leo-Pekka Lyytikinen, Emma Raitoharju, Ilkka Seppl, Antti-Pekka Sarin, Samuli Ripatti, Aarne Palotie, Markus Perola, Jorma S. Viikari, Sirpa Jalkanen, Mikael Maksimow, Veikko Salomaa, Marko Salmi, Johannes Kettunen, Olli T. Raitakari. Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. The American Journal of Human Genetics, 2017; 100 (1): 40 DOI: 10.1016/j.ajhg.2016.11.007

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Inflammatory Disease Prospects Discovered - Anti Aging News

Source:
http://www.hon.ch/cgi-bin/confevent?aff2+CONF13462

The conference, under the patronage of Commissioner John Dalli, offers discussion on the future organisation of hospital services.Source:
http://www.hon.ch/RSS/AUDIO/Conf/THEME/G07.574.124.xml

As a part of an international congress series, COSMODERMoutlines a forum where clinical dermatologists, academicdermatologists, and scientists have an opportunity todiscuss both background and practical impact of ageing,aesthetics and related conditions and diseases, and toexperience the latest developments and achievements intechnology, technical equipment, and drug development.

Two day course provides an update of selected topics in neurology and clinical neurophysiology.

The course objectives include:
• Quantifying Gait Disorders in Aging
• Motor Impairments in Aging and AD; Healthy Aging
• Motor Disorders and Age Related Common Neuropathologies
• New Approaches to Measuring Performances in Community-Dwelling Elders
• Cardiovascular Risk Factors and Cognition in Elders
• CNS Immune Mediated Conditions
• PNS Immune Mediated Conditions
• Cognition, Motor Function and Aging

This course is suitable for neurologists, neuroscientists, and general internists, gerontologists, psychiatrists and physiatrists, anesthesiologists and allied health professionals with a particular interest in patients with neurological disorders who wish to update their knowledge of the mechanisms and treatments of these disorders, and toimprove their expertise in clinical neurophysiology as practiced in their private offices.