With significant investments being made into biotechnology and research and development (R&D), life science organizations are becoming increasingly profitable targets for cybercriminals. Tremendous strides are being made in terms of scientific discoveries and companies must also keep pace by managing security risks and protecting scientific data.
One cybersecurity report found that ransomware attacks a form of malware that locks users out of their devices or files until a ransom is paid increased by 485% in 2020 compared to 2019, likely influenced by the COVID-19 pandemic. Additionally, another report found that the average total cost of a data breach in the pharmaceutical industry was $5.06 million.
In light of these rising cybersecurity risks and the threats they pose, Technology Networks spoke to Zach Powers, chief information security officer at Benchling, an R&D cloud platform for the biotechnology industry. We discuss why the biotechnology industry is being targeted by cybercriminals, the importance of data security and how the industry can mitigate these threats.
Sarah Whelan (SW): Can you explain what the Benchling R&D Cloud is, and how it is designed to advance scientific research and development? How can this benefit small academic laboratories through to large-scale biotechnology companies?
Zach Powers (ZP): Benchling was started with a vision of making research and development what its meant to be a collaborative process to turn ideas into scientific progress. In the past few years with the pandemic, this vision has felt more urgent and important than ever. Now, more than 200,000 scientists use Benchlings R&D Cloud as a central source of truth for biotech R&D to centralize data, improve collaboration and access insights, ultimately accelerating the path to discovery.
Looking to examples of how our R&D Cloud facilitates progress in the scientific community we helped Syngenta go from data silos to data as an advantage, now with a data infrastructure that serves 90 locations across different languages, regulations and time zones in their mission to build crops that require fewer inputs while producing great outputs. Using Benchling, Syngenta reported a 72% improvement in sharing data across geos and a large team.
SW: What considerations need to be made in terms of data security for these types of cloud-based platforms?
ZP: Biotech organizations generate revenue based on intellectual property, and if compromised, a great deal of revenue stands to be lost. These organizations are also highly regulated due to the potential human impact of their products and complying with regulations can make or break the organizations ability to compete.
Both of these factors mean that for a cloud-based platform like Benchling, maintaining industry-leading security, privacy and compliance standards for biotech customers is paramount. Enterprise software as a service (SaaS) companies have a responsibility to develop cloud software and infrastructure securely. To do this, they use automated vulnerability management, routine penetration testing, asset management, configuration management, threat detection and response engineering, etc. The end result is that many cloud software products undergo more security scrutiny, on a more frequent basis, than on-premises technologies do. Not all cloud products are the same when it comes to security, but it is becoming increasingly common for enterprise SaaS companies to approach security in this way. When evaluating cloud platforms, customers should evaluate how much an enterprise SaaS company invests in security on an ongoing basis; is there an economy of scale on security that the customer can benefit from?
SW: How important is data security and governance to the industry, and how has this changed over the years as new discoveries are made and biotechnology becomes a more lucrative target for cybercriminals?
ZP: In recent years, threat actors have become more advanced and are highly funded, educated and organized businesses. Whats more, the most dangerous threat actors are being employed by adversaries of the USA and European Union. These organizations are in business to make profits, and many even have revenue targets. They aim to gain illegal access to some of the worlds most sensitive intellectual property for financial gain.
Pharmaceutical companies are now routinely targeted and attacked by these advanced threat actors, and in 2021 almost all (98%) of pharmaceutical companies experienced at least one security intrusion. In fact, over 20% of businesses have lost business-critical data or intellectual property in the last year alone.
It is clear that robust data security and governance are more important than ever, especially as the biotechnology industry continues to increase in value with the influx of valuable data it generates.
SW: What lessons do you think life sciences and biotechnology institutions can take from other industries regarding managing security risks?
ZP: Managing security risks appropriately today requires engineering, automation, real-time analytics, threat intelligence, significant tooling etc. It also takes a strategy of applying security throughout an organization, with multiple layers of defense, points of detection and built-in response options. This level of investment can seem daunting, but against adversaries who are well funded and are singularly focused on their targets, doing less only makes it easier for a threat actor to accomplish their goals. In the security industry, we often talk about the cost to the attacker and how appropriately investing in security can raise the cost sufficiently to either deter an attacker or slow down their attacks sufficiently for detection mechanisms to trigger and response plans to be executed. Threat actors consider the cost to carry out an attack; it is a business after all. Biotech institutions have the ability to influence that cost model.
When evaluating whether to invest in security at this level, many life sciences and biotech institutions have sticker shock as the cost of security is rising rapidly year over year. The advice I give biotech institutions is to look at how many other industries have taken advantage of the economies of scale that mature cloud computing companies can offer on security, resiliency, disaster response and more. If a biotech institution is not ready to invest materially in security themselves, building out the type of world-class security program and capabilities necessary to protect data today, then they can still get secure outcomes by moving their data and workflows into cloud platforms that have invested materially in security. More times than not, mature cloud platforms have invested orders of magnitude more in security than their customers do and continue to on an ongoing basis. No security strategy is perfect, but a strategy that takes advantage of the economies of scale on security that mature cloud platforms provide tends to fare far better than not.
There is another fundamental benefit to approaching security in this way. The adoption of a cloud-first strategy can significantly increase a biotech institutions data liquidity. Cloud architectures excel at enabling data to be found, to be accessed by those who need it, be interoperable between disparate systems and to be reusable. These are known as the FAIR data principles. It is a key focus for biotech institutions today, which have struggled with data residing in disparate, on-premises silos for years.
We can again draw lessons from many other industries, looking at how they evolved and profited from greater data liquidity. For example, enterprise SaaS, banking and healthcare each came to view cloud computing and more modern security as keys to unlocking data liquidity, supporting rapid growth and unparalleled innovation. If data liquidity is the destination, then the easiest road to take is via cloud computing and data platforms. Cloud computing and data platforms bring consistency in data modeling, easily allow for programmatic interfaces, allow for easier governance and security assurance and allow people to find, access and use data readily.
SW: What changes do you think are needed in the future to ensure data security as science advances? What are the biggest challenges that need to be addressed?
ZP: One of the biggest challenges I see is a distrust in cloud technology, which is, unfortunately, a more common sentiment in biotech, particularly in Europe. A lot of biotech institutions are still adhering to a security strategy from the late 1990s, using on-premises technology and essentially using firewalls as the first and only line of defense. More times than not, maintaining an on-premises strategy exposes you to more risk because 100% of the security responsibility and resourcing is on you. Most companies that distrust cloud computing are actually less secure than the cloud providers they distrust.
There are many myths about whether or not cloud computing is secure and its important to separate fact from fiction. When we look at breach statistics, nothing in the data says that on-premises technologies are more secure. But beyond taking a data-driven approach to making security decisions, the most important lens I can offer to change attitudes around the security of cloud computing is that of economies of scale. Companies that adopt cloud and enterprise SaaS take advantage of economies of scale on security that modern software companies provide. Enterprise SaaS companies have a responsibility for security, and they have security capabilities and teams beyond what most companies can afford.
Its the same with Benchling, security is an integral part of the product were offering to our customers. To this aim, we invest far more in security than most customers can afford to, and we have an abundance of expertise. Benchling embeds security engineering into our software development lifecycle and cloud infrastructure operations. Vulnerability testing happens daily, all code checked into production undergoes security testing and any security issues found are fixed within industry-leading service level agreements.
Biotech institutions can get a more secure outcome by taking advantage of cloud software and platforms. We take care of the hard stuff in security so that our customers can focus on advancing science and delivering humanity-impacting products.
Zach Powers was speaking to Sarah Whelan, Science Writer for Technology Networks.
See the rest here:
Tackling Cybersecurity Threats in the Biotechnology Industry - Technology Networks
- Production of ethanol from winter barley by the EDGE (enhanced dry grind enzymatic) process [Last Updated On: August 17th, 2024] [Originally Added On: April 29th, 2010]
- A high-throughput transient gene expression system for switchgrass (Panicum virgatum L.) seedlings [Last Updated On: August 17th, 2024] [Originally Added On: May 8th, 2010]
- Cellulose crystallinity index: measurement techniques and their impact on interpreting cellulase performance [Last Updated On: August 17th, 2024] [Originally Added On: May 25th, 2010]
- Comparing the fermentation performance of Escherichia coli KO11, Saccharomyces cerevisiae 424A(LNH-ST) and Zymomonas mobilis AX101 for cellulosic ethanol production [Last Updated On: August 17th, 2024] [Originally Added On: May 28th, 2010]
- Enzymatic digestibility and ethanol fermentability of AFEX-treated starch-rich lignocellulosics such as corn silage and whole corn plant [Last Updated On: August 17th, 2024] [Originally Added On: June 10th, 2010]
- Improved xylose and arabinose utilization by an industrial recombinant Saccharomyces cerevisiae strain using evolutionary engineering [Last Updated On: August 17th, 2024] [Originally Added On: June 16th, 2010]
- Effects of enzyme feeding strategy on ethanol yield in fed-batch simultaneous saccharification and fermentation of spruce at high dry matter [Last Updated On: August 17th, 2024] [Originally Added On: June 26th, 2010]
- Impact of dual temperature profile in dilute acid hydrolysis of spruce for ethanol production [Last Updated On: August 17th, 2024] [Originally Added On: July 2nd, 2010]
- Ethanol production from mixtures of wheat straw and wheat meal [Last Updated On: August 17th, 2024] [Originally Added On: July 6th, 2010]
- Earning Cash – Selling Old Mobile Phones [Last Updated On: August 17th, 2024] [Originally Added On: July 7th, 2010]
- Earning Cash – Selling Old Mobile Phones [Last Updated On: August 17th, 2024] [Originally Added On: July 7th, 2010]
- Improving simultaneous saccharification and co-fermentation of pretreated wheat straw using both enzyme and substrate feeding [Last Updated On: August 17th, 2024] [Originally Added On: August 3rd, 2010]
- Practical screening of purified cellobiohydrolases and endoglucanases with alpha-cellulose and specification of hydrodynamics [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Techno-economic evaluation of stillage treatment with anaerobic digestion in a softwood-to-ethanol process [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Cross-reactions between engineered xylose and galactose pathways in recombinant Saccharomyces cerevisiae [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Rapid optimization of enzyme mixtures for deconstruction of diverse pretreatment/biomass feedstock combinations [Last Updated On: August 17th, 2024] [Originally Added On: October 13th, 2010]
- Automated saccharification assay for determination of digestibility in plant materials [Last Updated On: August 17th, 2024] [Originally Added On: November 7th, 2010]
- Biodetoxification of toxins generated from lignocellulose pretreatment using a newly isolated fungus, Amorphotheca resinae ZN1, and the consequent ethanol fermentation [Last Updated On: August 17th, 2024] [Originally Added On: November 28th, 2010]
- Lignin monomer composition affects Arabidopsis cell-wall degradability after liquid hot water pretreatment [Last Updated On: August 17th, 2024] [Originally Added On: December 11th, 2010]
- Thermostable endoglucanases in the liquefaction of hydrothermally pretreated wheat straw [Last Updated On: August 17th, 2024] [Originally Added On: February 6th, 2011]
- Cellulose accessibility limits the effectiveness of minimum cellulase loading on the efficient hydrolysis of pretreated lignocellulosic substrates [Last Updated On: August 17th, 2024] [Originally Added On: February 14th, 2011]
- Arsenal of plant cell wall degrading enzymes reflects host preference among plant pathogenic fungi [Last Updated On: August 17th, 2024] [Originally Added On: February 16th, 2011]
- Hemicellulases and auxiliary enzymes for improved conversion of lignocellulosic biomass to monosaccharides [Last Updated On: August 17th, 2024] [Originally Added On: February 22nd, 2011]
- Two-step synthesis of fatty acid ethyl ester from soybean oil catalyzed by Yarrowia lipolytica lipase [Last Updated On: August 17th, 2024] [Originally Added On: March 6th, 2011]
- Topochemical distribution of lignin and hydroxycinnamic acids in sugar-cane cell walls and its correlation with the enzymatic hydrolysis of polysaccharides [Last Updated On: August 17th, 2024] [Originally Added On: March 17th, 2011]
- Direct ethanol production from cellulosic materials using a diploid strain of Saccharomyces cerevisiae with optimized cellulase expression [Last Updated On: August 17th, 2024] [Originally Added On: April 17th, 2011]
- Isolation of xylose isomerases by sequence- and function-based screening from a soil metagenome library [Last Updated On: August 17th, 2024] [Originally Added On: May 8th, 2011]
- Low temperature lignocellulose pretreatment: effects and interactions of pretreatment pH are critical for maximizing enzymatic monosaccharide yields from wheat straw [Last Updated On: August 17th, 2024] [Originally Added On: May 15th, 2011]
- Effect of mixing on enzymatic hydrolysis of steam-pretreated spruce: a quantitative analysis of conversion and power consumption [Last Updated On: August 17th, 2024] [Originally Added On: May 15th, 2011]
- Thermostable recombinant xylanases from Nonomuraea flexuosa and Thermoascus aurantiacus show distinct properties in the hydrolysis of xylans and pretreated wheat straw [Last Updated On: August 17th, 2024] [Originally Added On: May 22nd, 2011]
- Investigation of tension wood formation and 2,6-dichlorbenzonitrile application in short rotation coppice willow composition and enzymatic saccharification [Last Updated On: August 17th, 2024] [Originally Added On: May 29th, 2011]
- Aiming the complete utilization of sugar beet pulp through mild acid and hydrothermal pretreatment followed by enzymatic digestion [Last Updated On: August 17th, 2024] [Originally Added On: June 5th, 2011]
- Alkaline peroxide pretreatment of corn stover: effects of biomass, peroxide, and enzyme loading and composition on yields of glucose and xylose [Last Updated On: August 17th, 2024] [Originally Added On: June 12th, 2011]
- In-situ lignocellulosic unlocking mechanism in termite for carbohydrate hydrolysis: critical lignin modification [Last Updated On: August 17th, 2024] [Originally Added On: June 19th, 2011]
- Supplementation with xylanase and beta-xylosidase to reduce xylo-oligomer and xylan inhibition of enzymatic hydrolysis of cellulose and pretreated corn stover [Last Updated On: August 17th, 2024] [Originally Added On: June 26th, 2011]
- Co-hydrolysis of hydrothermal and dilute acid pretreated Populus slurries to support development of a high-throughput pretreatment system [Last Updated On: August 17th, 2024] [Originally Added On: July 17th, 2011]
- Evaluation of preservation methods for improving biogas production and enzymatic conversion yields of annual crops [Last Updated On: August 17th, 2024] [Originally Added On: July 24th, 2011]
- Simultaneous saccharification and co-fermentation of lignocellulosic residues from commercial furfural production and corn kernels using different nutrient media [Last Updated On: August 17th, 2024] [Originally Added On: July 31st, 2011]
- Increased isobutanol production in Saccharomyces cerevisiae by overexpression of genes in valine metabolism [Last Updated On: August 17th, 2024] [Originally Added On: July 31st, 2011]
- Bioprospecting metagenomics of decaying wood: mining for new glycoside hydrolases [Last Updated On: August 17th, 2024] [Originally Added On: August 7th, 2011]
- Functional characterization of cellulases identified from the cow rumen fungus neocallimastix patriciarum W5 by transcriptomic and secretomic analyses [Last Updated On: August 17th, 2024] [Originally Added On: August 21st, 2011]
- Simultaneous utilization of glucose and xylose for lipid production by Trichosporon cutaneum [Last Updated On: August 17th, 2024] [Originally Added On: August 28th, 2011]
- Conversion of deoxynivalenol to 3-acetyldeoxynivalenol in barley derived fuel ethanol co-products with yeast expressing trichothecene 3-O-acetyltransferases [Last Updated On: August 17th, 2024] [Originally Added On: September 4th, 2011]
- Comparative performance of precommercial cellulases hydrolyzing pretreated corn stover [Last Updated On: August 17th, 2024] [Originally Added On: September 11th, 2011]
- Impact of pretreatment and downstream processing technologies on economics and energy use in cellulosic ethanol production [Last Updated On: August 17th, 2024] [Originally Added On: September 11th, 2011]
- A kinetic model for quantitative evaluation of the effect of H2 and osmolarity on hydrogen production by Caldicellulosiruptor saccharolyticus [Last Updated On: August 17th, 2024] [Originally Added On: September 18th, 2011]
- High level secretion of cellobiohydrolases by Saccharomyces cerevisiae [Last Updated On: August 17th, 2024] [Originally Added On: September 18th, 2011]
- How recombinant swollenin from Kluyveromyces lactis affects cellulosic substrates and accelerates their hydrolysis [Last Updated On: August 17th, 2024] [Originally Added On: September 25th, 2011]
- Bio-conversion of paper sludge to biofuel by simultaneous saccharification and fermentation using a cellulase of paper sludge origin and thermotolerant Saccharomyces cerevisiae TJ14 [Last Updated On: August 17th, 2024] [Originally Added On: October 2nd, 2011]
- Biogenic hydrogen and methane production from Chlorella vulgaris and Dunaliella tertiolecta biomass [Last Updated On: August 17th, 2024] [Originally Added On: October 2nd, 2011]
- The enhancement of enzymatic hydrolysis of lignocellulosic substrates by the addition of accessory enzymes such as xylanase: is it an additive or synergistic effect? [Last Updated On: August 17th, 2024] [Originally Added On: October 9th, 2011]
- Biotechnology [Last Updated On: August 17th, 2024] [Originally Added On: October 10th, 2011]
- Biology: Biotechnology: Gene Cloning [Last Updated On: August 17th, 2024] [Originally Added On: October 10th, 2011]
- What Does a Biotechnology Course Look Like? [Last Updated On: August 17th, 2024] [Originally Added On: October 10th, 2011]
- Demo day by SCT Biotechnology Branch 2011 passouts [Last Updated On: August 17th, 2024] [Originally Added On: October 12th, 2011]
- Biotechnology Program Video [Last Updated On: August 17th, 2024] [Originally Added On: October 12th, 2011]
- Introduction To Industrial Biotechnology [Last Updated On: August 17th, 2024] [Originally Added On: October 13th, 2011]
- MSc Molecular Biotechnology -- Come to the School of Biosciences, University of Birmingham, UK - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 13th, 2011]
- Oxbridge Biotechnology Roundtable - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 15th, 2011]
- fermentation technology (biotechnology practical class) UNIVERSITY OF MALAYA - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 15th, 2011]
- Biotechnology: Learn about New Biological Medicines in Development - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 15th, 2011]
- Improving L-arabinose utilization of pentose fermenting Saccharomyces cerevisiae cells by heterologous expression of L-arabinose transporting sugar transporters [Last Updated On: August 17th, 2024] [Originally Added On: October 16th, 2011]
- The promoting effect of by-products from Irpex lacteus on subsequent enzymatic hydrolysis of bio-pretreated cornstalks [Last Updated On: August 17th, 2024] [Originally Added On: October 16th, 2011]
- Biotechnology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 16th, 2011]
- BiotechNaukri #Biotechnology Jobs - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 16th, 2011]
- bio-technology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 16th, 2011]
- BioBytes - Biotechnology and food flavoring - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 19th, 2011]
- Stine Biotechnology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 22nd, 2011]
- Effects of alkaline or liquid-ammonia treatment on crystalline cellulose: Changes in crystalline structure and effects on enzymatic digestibility [Last Updated On: August 17th, 2024] [Originally Added On: October 23rd, 2011]
- Transcriptome analysis of Aspergillus niger grown on sugarcane bagasse [Last Updated On: August 17th, 2024] [Originally Added On: October 23rd, 2011]
- A cellular automaton model of crystalline cellulose hydrolysis by cellulases [Last Updated On: August 17th, 2024] [Originally Added On: October 23rd, 2011]
- Application of a Burkholderia cepacia lipase-immobilized silica monolith to the batch and continuous biodiesel production with a stoichiometric mixture of methanol and crude Jatropha oil [Last Updated On: August 17th, 2024] [Originally Added On: October 23rd, 2011]
- Algal Biotechnology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 24th, 2011]
- Techniques of Biotechnology, Part 1 of 4 - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 25th, 2011]
- Biotechnology days in Macedonia II - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 26th, 2011]
- BioBytes: Forensics and Biotechnology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 26th, 2011]
- Faces of Biotechnology: What is Biotechnology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 26th, 2011]
- Mucosal and systemic responses/Dr Thomas Muster-AVIR Green Hills Biotechnology-World Vaccine - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 26th, 2011]
- Unlimited Income Potential in Bio-Technology, Part 1 - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 27th, 2011]
- Islam Ahmadiyya Questions: Biotechnology, Portraits, Ring, Prayers, Dreams, Adopted Children - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 28th, 2011]