Press release
Cambridge, MA U.S.A. (September 26, 2022) Allarity Therapeutics, Inc. (Nasdaq: ALLR) (Allarity or the Company), a clinical-stage pharmaceutical company developing novel oncology therapeutics together with drug-specific DRP companion diagnostics for personalized cancer care, today announced the appointment of Jerry McLaughlin as a new member of its Board of Directors, effective October 1, 2022.
Mr. McLaughlin is a highly accomplished biotechnology executive with extensive experience in financing, drug development, licensing, commercialization, and product lifecycle management. Mr. McLaughlin is expected to serve on the compensation, and audit committees as an independent director.
I am delighted that Jerry has chosen to join Allaritys board at this crucial time in our evolution, said Dr. Duncan Moore, Allaritys Chairman of the Board. His operational experience in clinical stage therapeutic development and capital markets acumen will be of great value as we continue to implement the Companys combination therapy-focused strategy.
Mr. McLaughlin said: I firmly believe Allarity Therapeutics is in a unique position to become a leader within the personalized medicine space by developing novel combination oncology therapies together with the Companys unique DRP companion diagnostics. Allaritys recent strategic shift is aligned with the ongoing patient and market realities in oncology, as we continue to see substantially higher patient benefits with combination therapies. I look forward to supporting the CEO, Jim Cullem, and the rest of the Allarity team in unlocking both the clinical and commercial potential of this strategy.
Mr. McLaughlin has three decades of experience in leading operational and executive management roles. He made key contributions to significant life science milestones, including product launches, acquisitions, and financings. He is currently serving as CEO and Board Member of Life Biosciences, LLC, a development-stage biopharmaceutical company advancing therapeutics for patients with neurological and psychiatric diseases. Prior to serving in this role, he was President, CEO, and Member of the Board of Directors at Neos Therapeutics (acquired by Aytu BioScience.) Before joining Neos Therapeutics, he served as President, CEO, and Member of the Board of Directors at AgeneBio, Inc. Earlier in his career, he held corporate leadership roles at NuPathe, Inc., Endo Pharmaceuticals Inc., and Merck & Co., Inc. He received his B.A. from Dickinson College and his MBA from Villanova University in Pennsylvania.
About Allarity Therapeutics
Allarity Therapeutics, Inc. (Nasdaq: ALLR) develops drugs for personalized treatment of cancer guided by its proprietary and highly validated companion diagnostic technology, the DRP platform. The Company has a mature portfolio of three drug candidates: stenoparib, a PARP inhibitor in Phase 2 development for ovarian cancer; dovitinib, a post-Phase 3 pan-tyrosine kinase inhibitor; and the European rights to IXEMPRA (Ixabepilone), a microtubule inhibitor approved in the U.S. and marketed by R-PHARM U.S. for the treatment of second-line metastatic breast cancer, currently in Phase 2 development in Europe for the same indication. Additionally, the Company has rights in two secondary assets: 2X-111, a liposomal formulation of doxorubicin in Phase 2 development for metastatic breast cancer and/or glioblastoma multiforme (GBM), which is the subject of discussions for a restructured out-license to Smerud Medical Research International AS; and LiPlaCis, a liposomal formulation of cisplatin and its accompanying DRP, being developed via a partnership with Chosa ApS, an affiliate of Smerud Medical Research International, for late-stage metastatic breast cancer. The Company is headquartered in the United States and maintains an R&D facility in Hoersholm, Denmark. For more information, please visit the Companys website at http://www.Allarity.com.
About the Drug Response Predictor DRP Companion Diagnostic
Allarity uses its drug-specific DRP to select those patients who, by the genetic signature of their cancer, are found to have a high likelihood of responding to the specific drug. By screening patients before treatment, and only treating those patients with a sufficiently high DRP score, the therapeutic response rate can be significantly increased. The DRP method builds on the comparison of sensitive vs. resistant human cancer cell lines, including transcriptomic information from cell lines combined with clinical tumor biology filters and prior clinical trial outcomes. DRP is based on messenger RNA from patient biopsies. The DRP platform has proven its ability to provide a statistically significant prediction of the clinical outcome from drug treatment in cancer patients in 37 out of 47 clinical studies that were examined (both retrospective and prospective), including ongoing, prospective Phase 2 trials of Stenoparib and IXEMPRA. The DRP platform, which can be used in all cancer types and is patented for more than 70 anti-cancer drugs, has been extensively published in peer reviewed literature.
Follow Allarity on Social Media
Facebook: https://www.facebook.com/AllarityTx/ LinkedIn: https://www.linkedin.com/company/allaritytx/ Twitter: https://twitter.com/allaritytx
Forward-Looking Statements
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements provide Allaritys current expectations or forecasts of future events. The words anticipates, believe, continue, could, estimate, expect, intends, may, might, plan, possible, potential, predicts, project, should, would and similar expressions may identify forward-looking statements, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include, but are not limited to, statements related to clinical and commercial potential due to the Company advancing dovitinib in combination with another therapeutic candidate or other approved drug, any statements related to ongoing clinical trials for stenoparib as a monotherapy or in combination with another therapeutic candidate for the treatment of advanced ovarian cancer, or ongoing clinical trials (in Europe) for IXEMPRA for the treatment of metastatic breast cancer, and statements relating to the effectiveness of the Companys DRP companion diagnostics platform in predicting whether a particular patient is likely to respond to a specific drug. Any forward-looking statements in this press release are based on managements current expectations of future events and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in or implied by such forward-looking statements. These risks and uncertainties include, but are not limited to,the risk that results of a clinical study do not necessarily predict final results and that one or more of the clinical outcomes may materially change following more comprehensive reviews of the data, and as more patient data become available, the risk that results of a clinical study are subject to interpretation and additional analyses may be needed and/or may contradict such results, the receipt of regulatory approval for dovitinib or any of our other therapeutic candidates or, if approved, the successful commercialization of such products, the risk of cessation or delay of any of the ongoing or planned clinical trials and/or our development of our product candidates, the risk that the results of previously conducted studies will not be repeated or observed in ongoing or future studies involving our therapeutic candidates, and the risk that the current COVID-19 pandemic will impact the Companys current and future clinical trials and the timing of the Companys preclinical studies and other operations. For a discussion of other risks and uncertainties, and other important factors, any of which could cause our actual results to differ from those contained in the forward-looking statements, see the section entitled Risk Factors in our Form S-1 registration statementon file with theSecurities and Exchange Commission, available at the Securities and Exchange Commissions website atwww.sec.gov, and as well as discussions of potential risks, uncertainties and other important factors in the Companys subsequent filings with theSecurities and Exchange Commission. All information in this press release is as of the date of the release, and the Company undertakes no duty to update this information unless required by law.
###
Company Contact:
Thomas JensenSenior V.P. of Investor Relationsinvestorrelations@allarity.com
Investor Relations:
Chuck PadalaLifeSci Advisors+1(646) 627-8390chuck@lifesciadvisors.comU.S. Media Contact:
Mike Beyer Sam Brown, Inc. +1 (312) 961-2502 mikebeyer@sambrown.com
EU Media Contact:
Thomas PedersenCarrotize PR & Communications +45 6062 9390tsp@carrotize.com
Read the rest here:
Allarity Therapeutics Appoints Seasoned Biotechnology Executive Jerry McLaughlin to Board of Directors - GlobeNewswire
- Production of ethanol from winter barley by the EDGE (enhanced dry grind enzymatic) process [Last Updated On: August 17th, 2024] [Originally Added On: April 29th, 2010]
- A high-throughput transient gene expression system for switchgrass (Panicum virgatum L.) seedlings [Last Updated On: August 17th, 2024] [Originally Added On: May 8th, 2010]
- Cellulose crystallinity index: measurement techniques and their impact on interpreting cellulase performance [Last Updated On: August 17th, 2024] [Originally Added On: May 25th, 2010]
- Comparing the fermentation performance of Escherichia coli KO11, Saccharomyces cerevisiae 424A(LNH-ST) and Zymomonas mobilis AX101 for cellulosic ethanol production [Last Updated On: August 17th, 2024] [Originally Added On: May 28th, 2010]
- Enzymatic digestibility and ethanol fermentability of AFEX-treated starch-rich lignocellulosics such as corn silage and whole corn plant [Last Updated On: August 17th, 2024] [Originally Added On: June 10th, 2010]
- Improved xylose and arabinose utilization by an industrial recombinant Saccharomyces cerevisiae strain using evolutionary engineering [Last Updated On: August 17th, 2024] [Originally Added On: June 16th, 2010]
- Effects of enzyme feeding strategy on ethanol yield in fed-batch simultaneous saccharification and fermentation of spruce at high dry matter [Last Updated On: August 17th, 2024] [Originally Added On: June 26th, 2010]
- Impact of dual temperature profile in dilute acid hydrolysis of spruce for ethanol production [Last Updated On: August 17th, 2024] [Originally Added On: July 2nd, 2010]
- Ethanol production from mixtures of wheat straw and wheat meal [Last Updated On: August 17th, 2024] [Originally Added On: July 6th, 2010]
- Earning Cash – Selling Old Mobile Phones [Last Updated On: August 17th, 2024] [Originally Added On: July 7th, 2010]
- Earning Cash – Selling Old Mobile Phones [Last Updated On: August 17th, 2024] [Originally Added On: July 7th, 2010]
- Improving simultaneous saccharification and co-fermentation of pretreated wheat straw using both enzyme and substrate feeding [Last Updated On: August 17th, 2024] [Originally Added On: August 3rd, 2010]
- Practical screening of purified cellobiohydrolases and endoglucanases with alpha-cellulose and specification of hydrodynamics [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Techno-economic evaluation of stillage treatment with anaerobic digestion in a softwood-to-ethanol process [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Cross-reactions between engineered xylose and galactose pathways in recombinant Saccharomyces cerevisiae [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Rapid optimization of enzyme mixtures for deconstruction of diverse pretreatment/biomass feedstock combinations [Last Updated On: August 17th, 2024] [Originally Added On: October 13th, 2010]
- Automated saccharification assay for determination of digestibility in plant materials [Last Updated On: August 17th, 2024] [Originally Added On: November 7th, 2010]
- Biodetoxification of toxins generated from lignocellulose pretreatment using a newly isolated fungus, Amorphotheca resinae ZN1, and the consequent ethanol fermentation [Last Updated On: August 17th, 2024] [Originally Added On: November 28th, 2010]
- Lignin monomer composition affects Arabidopsis cell-wall degradability after liquid hot water pretreatment [Last Updated On: August 17th, 2024] [Originally Added On: December 11th, 2010]
- Thermostable endoglucanases in the liquefaction of hydrothermally pretreated wheat straw [Last Updated On: August 17th, 2024] [Originally Added On: February 6th, 2011]
- Cellulose accessibility limits the effectiveness of minimum cellulase loading on the efficient hydrolysis of pretreated lignocellulosic substrates [Last Updated On: August 17th, 2024] [Originally Added On: February 14th, 2011]
- Arsenal of plant cell wall degrading enzymes reflects host preference among plant pathogenic fungi [Last Updated On: August 17th, 2024] [Originally Added On: February 16th, 2011]
- Hemicellulases and auxiliary enzymes for improved conversion of lignocellulosic biomass to monosaccharides [Last Updated On: August 17th, 2024] [Originally Added On: February 22nd, 2011]
- Two-step synthesis of fatty acid ethyl ester from soybean oil catalyzed by Yarrowia lipolytica lipase [Last Updated On: August 17th, 2024] [Originally Added On: March 6th, 2011]
- Topochemical distribution of lignin and hydroxycinnamic acids in sugar-cane cell walls and its correlation with the enzymatic hydrolysis of polysaccharides [Last Updated On: August 17th, 2024] [Originally Added On: March 17th, 2011]
- Direct ethanol production from cellulosic materials using a diploid strain of Saccharomyces cerevisiae with optimized cellulase expression [Last Updated On: August 17th, 2024] [Originally Added On: April 17th, 2011]
- Isolation of xylose isomerases by sequence- and function-based screening from a soil metagenome library [Last Updated On: August 17th, 2024] [Originally Added On: May 8th, 2011]
- Low temperature lignocellulose pretreatment: effects and interactions of pretreatment pH are critical for maximizing enzymatic monosaccharide yields from wheat straw [Last Updated On: August 17th, 2024] [Originally Added On: May 15th, 2011]
- Effect of mixing on enzymatic hydrolysis of steam-pretreated spruce: a quantitative analysis of conversion and power consumption [Last Updated On: August 17th, 2024] [Originally Added On: May 15th, 2011]
- Thermostable recombinant xylanases from Nonomuraea flexuosa and Thermoascus aurantiacus show distinct properties in the hydrolysis of xylans and pretreated wheat straw [Last Updated On: August 17th, 2024] [Originally Added On: May 22nd, 2011]
- Investigation of tension wood formation and 2,6-dichlorbenzonitrile application in short rotation coppice willow composition and enzymatic saccharification [Last Updated On: August 17th, 2024] [Originally Added On: May 29th, 2011]
- Aiming the complete utilization of sugar beet pulp through mild acid and hydrothermal pretreatment followed by enzymatic digestion [Last Updated On: August 17th, 2024] [Originally Added On: June 5th, 2011]
- Alkaline peroxide pretreatment of corn stover: effects of biomass, peroxide, and enzyme loading and composition on yields of glucose and xylose [Last Updated On: August 17th, 2024] [Originally Added On: June 12th, 2011]
- In-situ lignocellulosic unlocking mechanism in termite for carbohydrate hydrolysis: critical lignin modification [Last Updated On: August 17th, 2024] [Originally Added On: June 19th, 2011]
- Supplementation with xylanase and beta-xylosidase to reduce xylo-oligomer and xylan inhibition of enzymatic hydrolysis of cellulose and pretreated corn stover [Last Updated On: August 17th, 2024] [Originally Added On: June 26th, 2011]
- Co-hydrolysis of hydrothermal and dilute acid pretreated Populus slurries to support development of a high-throughput pretreatment system [Last Updated On: August 17th, 2024] [Originally Added On: July 17th, 2011]
- Evaluation of preservation methods for improving biogas production and enzymatic conversion yields of annual crops [Last Updated On: August 17th, 2024] [Originally Added On: July 24th, 2011]
- Simultaneous saccharification and co-fermentation of lignocellulosic residues from commercial furfural production and corn kernels using different nutrient media [Last Updated On: August 17th, 2024] [Originally Added On: July 31st, 2011]
- Increased isobutanol production in Saccharomyces cerevisiae by overexpression of genes in valine metabolism [Last Updated On: August 17th, 2024] [Originally Added On: July 31st, 2011]
- Bioprospecting metagenomics of decaying wood: mining for new glycoside hydrolases [Last Updated On: August 17th, 2024] [Originally Added On: August 7th, 2011]
- Functional characterization of cellulases identified from the cow rumen fungus neocallimastix patriciarum W5 by transcriptomic and secretomic analyses [Last Updated On: August 17th, 2024] [Originally Added On: August 21st, 2011]
- Simultaneous utilization of glucose and xylose for lipid production by Trichosporon cutaneum [Last Updated On: August 17th, 2024] [Originally Added On: August 28th, 2011]
- Conversion of deoxynivalenol to 3-acetyldeoxynivalenol in barley derived fuel ethanol co-products with yeast expressing trichothecene 3-O-acetyltransferases [Last Updated On: August 17th, 2024] [Originally Added On: September 4th, 2011]
- Comparative performance of precommercial cellulases hydrolyzing pretreated corn stover [Last Updated On: August 17th, 2024] [Originally Added On: September 11th, 2011]
- Impact of pretreatment and downstream processing technologies on economics and energy use in cellulosic ethanol production [Last Updated On: August 17th, 2024] [Originally Added On: September 11th, 2011]
- A kinetic model for quantitative evaluation of the effect of H2 and osmolarity on hydrogen production by Caldicellulosiruptor saccharolyticus [Last Updated On: August 17th, 2024] [Originally Added On: September 18th, 2011]
- High level secretion of cellobiohydrolases by Saccharomyces cerevisiae [Last Updated On: August 17th, 2024] [Originally Added On: September 18th, 2011]
- How recombinant swollenin from Kluyveromyces lactis affects cellulosic substrates and accelerates their hydrolysis [Last Updated On: August 17th, 2024] [Originally Added On: September 25th, 2011]
- Bio-conversion of paper sludge to biofuel by simultaneous saccharification and fermentation using a cellulase of paper sludge origin and thermotolerant Saccharomyces cerevisiae TJ14 [Last Updated On: August 17th, 2024] [Originally Added On: October 2nd, 2011]
- Biogenic hydrogen and methane production from Chlorella vulgaris and Dunaliella tertiolecta biomass [Last Updated On: August 17th, 2024] [Originally Added On: October 2nd, 2011]
- The enhancement of enzymatic hydrolysis of lignocellulosic substrates by the addition of accessory enzymes such as xylanase: is it an additive or synergistic effect? [Last Updated On: August 17th, 2024] [Originally Added On: October 9th, 2011]
- Biotechnology [Last Updated On: August 17th, 2024] [Originally Added On: October 10th, 2011]
- Biology: Biotechnology: Gene Cloning [Last Updated On: August 17th, 2024] [Originally Added On: October 10th, 2011]
- What Does a Biotechnology Course Look Like? [Last Updated On: August 17th, 2024] [Originally Added On: October 10th, 2011]
- Demo day by SCT Biotechnology Branch 2011 passouts [Last Updated On: August 17th, 2024] [Originally Added On: October 12th, 2011]
- Biotechnology Program Video [Last Updated On: August 17th, 2024] [Originally Added On: October 12th, 2011]
- Introduction To Industrial Biotechnology [Last Updated On: August 17th, 2024] [Originally Added On: October 13th, 2011]
- MSc Molecular Biotechnology -- Come to the School of Biosciences, University of Birmingham, UK - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 13th, 2011]
- Oxbridge Biotechnology Roundtable - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 15th, 2011]
- fermentation technology (biotechnology practical class) UNIVERSITY OF MALAYA - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 15th, 2011]
- Biotechnology: Learn about New Biological Medicines in Development - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 15th, 2011]
- Improving L-arabinose utilization of pentose fermenting Saccharomyces cerevisiae cells by heterologous expression of L-arabinose transporting sugar transporters [Last Updated On: August 17th, 2024] [Originally Added On: October 16th, 2011]
- The promoting effect of by-products from Irpex lacteus on subsequent enzymatic hydrolysis of bio-pretreated cornstalks [Last Updated On: August 17th, 2024] [Originally Added On: October 16th, 2011]
- Biotechnology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 16th, 2011]
- BiotechNaukri #Biotechnology Jobs - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 16th, 2011]
- bio-technology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 16th, 2011]
- BioBytes - Biotechnology and food flavoring - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 19th, 2011]
- Stine Biotechnology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 22nd, 2011]
- Effects of alkaline or liquid-ammonia treatment on crystalline cellulose: Changes in crystalline structure and effects on enzymatic digestibility [Last Updated On: August 17th, 2024] [Originally Added On: October 23rd, 2011]
- Transcriptome analysis of Aspergillus niger grown on sugarcane bagasse [Last Updated On: August 17th, 2024] [Originally Added On: October 23rd, 2011]
- A cellular automaton model of crystalline cellulose hydrolysis by cellulases [Last Updated On: August 17th, 2024] [Originally Added On: October 23rd, 2011]
- Application of a Burkholderia cepacia lipase-immobilized silica monolith to the batch and continuous biodiesel production with a stoichiometric mixture of methanol and crude Jatropha oil [Last Updated On: August 17th, 2024] [Originally Added On: October 23rd, 2011]
- Algal Biotechnology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 24th, 2011]
- Techniques of Biotechnology, Part 1 of 4 - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 25th, 2011]
- Biotechnology days in Macedonia II - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 26th, 2011]
- BioBytes: Forensics and Biotechnology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 26th, 2011]
- Faces of Biotechnology: What is Biotechnology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 26th, 2011]
- Mucosal and systemic responses/Dr Thomas Muster-AVIR Green Hills Biotechnology-World Vaccine - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 26th, 2011]
- Unlimited Income Potential in Bio-Technology, Part 1 - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 27th, 2011]
- Islam Ahmadiyya Questions: Biotechnology, Portraits, Ring, Prayers, Dreams, Adopted Children - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 28th, 2011]