Bioengineering | Clemson University, South Carolina

Guided by a faculty committed to the undergraduate and graduate research experience, bioengineering students apply engineering principles to understand and treat disease. Collaboration with physicians and entrepreneurs ensures that research focuses on high-priority health care challenges.

By providing high-quality undergraduate and graduate education, Clemson bioengineering prepares students to

The Page Morton Hunter Distinguished Seminar Series is held in Rhodes Annex 111 at 3:30 p.m. The C. Dayton Riddle Distinguished Seminar Series is held at CUBEInC at 5:30 p.m. Richard E. Swaja Guest Lectures as announced.

Page Morton Hunter seminars 9-3-2015 Dr. Hitesh Handa, University of Georgia

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Dyson Foundation US WinnersKayla Gainey Wilson, Tyler Ovington, and Alex Devon developed Glucosense as part of a Creative Inquiry class with Dr. Delphine Dean to improve health care in Tanzania. A low-cost method to test blood sugar, Glucosense has continually brought recognition to its designers. Now, the group is among the US winners of the James Dyson Foundation competition, which provides awards to help engineers realize their potential.

SPIEThe international society for optics and photonics, SPIE, elected Dr. David Kwartowitz, Senior Member in advance of its August, 2015, meeting.

2015 International Symposium on Organic Electronics and Bioelectronics

Venturewell E Team Program Stage IAptus Bioreactors, a program proposal headed by Dr. Dan Simionescu, has been accepted into Stage 1 by Venturewell. This award includes funding to attend a three-day workshop on how to better articulate the opportunity for the proposed innovation in the marketplace use of funds to support further development of the project/product.

NSF Epicenter Clemson University was selected by the National Science Foundation-funded National Center for Engineering Pathways to Innovation (Epicenter) to join the Pathways to Innovation Program. Dr. John DesJardins led the proposal submission. He is co-team leader and co-PI for the program. SFB Student Award for Outstanding ResearchLindsey Sanders, a student of Dr. Jiro Nagatomi, was selected to receive a 2015 Student Award for Outstanding Research [Ph.D. category] from the Society For Biomaterials. The award is given to student researchers who have shown outstanding achievement in biomaterials research.

National Academy of Inventors Angela Alexander-Bryant has been selected as an Honorary Student Member of the MUSC Chapter of the National Academy of Inventors. The honor is based upon work she presented in obtaining the 2014 MUSC Perry Halushka Research Day Innovation Award.

National Institute of General Medical Sciences Dr. Naren Vyavahare's team was recognized for developing nanoparticles that attach only to damaged fibers to deliver drugs to damaged blood vessels.

MUSC Research Day 2014 Award Winner Angela Alexander-Bryant, a PhD candidate and mentee of Dr. Andrew Jakymiw in the College of Dental Medicine at MUSC, won 1st place in the Innovations Award category at Student Research Day at Medical University of South Carolina. The annual event is open to students, postdoctoral residents and fellows who participated during the year in MUSC research programs.

Sigma Xi Recognizes Superior Poster Presentations Traveling with a group of students accompanied by mentor Dr. Jorge Rodriguez, undergraduate Taylor Gambon was awarded Superior Student Presenter in Engineering at the Scientific Research Societys 2014 International Research Conference. Taylor, who is advised by Dr. John DesJardins, also took Students Choice Award, second place.> The Presidents Office of Science and Technology Policy Proclaiming November as National Entrepreneurship Month, President Barack Obama noted, This month, we recognize the grit and determination of American inventors and innovators and their many contributions to our Nation, and we reaffirm our commitment to support these entrepreneurs as they develop the products, services, and ideas of tomorrow. The Office of Science and Technology Policy conducted interviews with some of last years University Innovation Fellows, among them Bre Przestrzelski, student of Dr. John DesJardins.

Advanced Functional Materials An image created by Dr. Frank Alexis is the frontispiece of Advanced Functional Materials Volume 24 Issue 37. The illustration accompanied his groups article on the use of X-ray excited luminescent nanoparticles to quantitatively measure intracellular drug release.

Finalists for 2014 Collegiate Inventors Competition Undergraduate students Ryan Gedney, Charles Laughlin, Nicholas Marais and Taylor Pate form a team that was chosen as one of seven finalists for the competition, which honors the latest in student creativity and innovation. The team, mentored by Dr. John DesJardins, was recognized for developing Insita Pro, an arthroscopic surgical tool to enhance repair of the rotator cuff.

TEDx Talk a National "Weekly Editor's Pick" Dr. John DesJardinss TEDx talk, Medical Implant Innovation, was chosen by TEDx editors for recognition on the national organizations website. Using a device he and then-student Eric Lucas designed, Dr. DesJardins described a future in which patients adjust prostheses to fit activities at work and play. The talk was presented at a TEDxGreenville conference in April, 2014.

Diabetes Technology Society Bronze Prize for First-Authored Student Abstract For her abstract, Glucosense: a Low-Cost Glucometer System for Resource-Poor Settings, Kayla Gainey, a student of Dr. Delphine Dean, will be recognized at the 14th DTS Annual Meeting, November 6-8, 2014. In addition to receiving travel, a monetary award, and other considerations, Kayla was asked to submit an original article to the September 2015 issue of the Journal of Diabetes Science and Technology.

Nature Biotechnology: Top Translational Junior Faculty in 2013 His six patents place Dr. Frank Alexis third on the list of five top translational junior faculty in 2013. The novel drug-delivery strategies he develops decrease toxicity by delivering drugs directly to the part of the body where they are needed.

SC Launch Funds Two Startups based on Bioengineering Technology Dr. Alexey Vertegel, Associate Professor and CEO of VRM Labs, is commercializing a novel Clemson technology for manufacturing cost-effective natural food preservatives for applications in pet food and animal feed industries. Dr. Naren Vyavahare, Hunter Endowed Chair and co-founder of ConnecTiss LLC, is developing a cosmeceutical product to prevent elastin degeneration to reduce signs of aging.

American Heart Association The associations Mid-Atlantic Affiliate awarded Dr. Bruce Gao its Winter 2014 Grant-in-Aid to study dynamic interaction of basement-membrane components with cardiomyocytes.

Engineering World Health For the second year running, the Clemson University Chapter of Engineering World Health sent a winning design entry to EWHs national competition to encourage the development of technical solutions that contribute to improved health care in developing countries. Tyler Ovington, Wilson Chan, Tyler Matt, and Jason Pierce were awarded 2nd place for their design, CryoCover: Low-Cost Neonatal Hypothermia Therapy. The students are supported by faculty and student mentors in the bioengineering design program.

NSF-Stanford-NCIIA Fellow Breanne Przestrzelski, a PhD candidate in Dr. John DesJardins lab, is a of Fellow the National Center for Engineering Pathways to Innovation (Epicenter), which is funded by the National Science Foundation as a partnership between Stanford University and the National Collegiate Inventors and Innovators Alliance.

NIH COBRE PHASE II Clemson University was awarded $11 million to expand SCBioCRAFT, the only bioengineering center funded by the NIH Centers of Biomedical Research Excellence program. PI Dr. Naren Vyavahare continues as center director.

NIH R01 Dr. Bruce Gao was awarded the R01, which is given for health-related research and development, for his proposal "Microfabricated coculture model: Myocyte rescue by TNT-transferred mitochondria."

First Place, UT El Paso LIMBS Design Competition Undergraduate students Sarah Stafford and Katelyn Rye andDr. Delphine Dean and John DesJardins won the UT El Paso LIMBS design competition for their work on neck braces for use in developing countries. The students mentor for this project, developed through Creative Inquiry, was Dr. Jorge Rodriguez.

Department Leads Team in Tanzania Led by Drs. Delphine Dean and John DesJardins a team of Clemson University students spent two weeks in Tanzania as part of Clemsons unique Creative Inquiry (CI) program, combining interdisciplinary undergraduate research with engaged learning. The team continues to design and create a number of medical products, ranging from a neonatal heating device for hospitals to an affordable glucose monitor for poor villages.

Rajan Gangadharan, a student of Dr. Guigen Zhang was awarded a National Science Foundation-sponsored travel award to attend the annual conference of the IBE. American Heart Association The associations Mid-Atlantic Affiliate awarded Dr. Bruce Gao and Ann Foley its Winter 2014 Grant-in-Aid. Dr. Gao will study dynamic interaction of basement-membrane components with cardiomyocytes. Dr. Foley will study the differentiation of pacemaker cells within the heart and in vitro.

Upstate Biomedical Technology A Clemson University department that helped pioneer the use of engineering principles to understand and treat disease is celebrating 50 years of awarding graduate degrees while helping prime the Upstate for what could be a boom in the medical-technology industry. National IDeA Symposium of Biomedical Research Excellence At the National Institutes of Health, National Institute of General Medical Sciences Fifth Biennial symposium, both faculty and students received travel awards. Dr. Jeoung Soo Lees presentation was selected as a highlighted poster. Dr. Lee and Nasim Nosoudi, a student in Dr. Naren Vyavahares lab, received Young Investigator travel awards. The following received Student travel awards: Siyu Ma, a PhD student in Dr. Bruce Gaos lab, and Laura McCallum and Anna Lu Carter, a PhD student and an undergraduate in Dr. Aggie Simionescus lab.

EurekaFest at Massachusetts Institute of Technology Kayla Gainey and Alex Devon, students of Dr. Delphine Dean presented to over 200 high school student in Invent teams. In addition, they were given a public showcase to demonstrate and discuss their GlucoSense invention.

NHLBI T32 Dylan Richards, a student in Dr. Ying Meis lab, has been awarded a T32 predoctoral training grant the National Heart, Lung, and Blood Institute. The grant, which will support training to improve cardiovascular therapies, is renewable.

EnterPrize Competition Alison Lamb, an alumna with a BS in bioengineering and an MBA, was a top-five finisher in the EnterPrize Award competition for her presentation and business plan. The project began in the lab of Dr. Karen Burg. Algernon Sydney Sullivan Student Award Elliot Mappus, a graduate student in Dr. Delphine Deans lab, received the Algernon Sydney Sullivan Student Award and a BS in bioengineering at graduation. The award is given for service to campus and community. Elliot, who worked with researchers at Clemson and the Medical University of South Carolina, studies neuroscience. He has been active as a resident hall senator, a Calhoun Honors mentor, an advocate for Habitat for Humanity, and a volunteer with the Barrier Islands Free Medical Clinic on Johns Island. Mappus is a supplemental instructor in organic chemistry.

American Society of Cataract and Refractive Surgery, Association for Research in Vision and Ophthalmology Glenn Hepfer, a student in Dr. Hai Yaos lab, was awarded best paper presentation in CORNEA Crosslinking at the 2014 Annual Meeting of the American Society of Cataract and Refractive Surgery. Glenn also presented a paper at and received a travel award for the 2014 Annual Meeting for the Association for Research in Vision and Ophthalmology. His research focus is treatment for keratoconus, a disease in which a weakened cornea protrudes into a conical shape, reducing visual acuity.

Society For Biomaterials International Business Plan Competition Suzanne Tabbaa, doctoral bioengineering student in Dr. Karen Burgs lab and Clemson University Research Foundation intern, won the second place judges' award and the first place audience award in the Society For Biomaterials International Business Plan Competition held at the Societys Annual Meeting. Her plan described translation to market of a breast cancer diagnostic developed at Clemson. Suzanne has been admitted to Clemsons MBAe program.

Goldwater Scholarships for Excellence in Science, Mathematics and Engineering Kate Showers, a junior working with Drs. Delphine Dean and David Kwartowitz, was one of two Clemson students awarded the scholarship, which recognizes a strong interest in research and a high level of scholarship. Kate is conducting research on pressure sensors that will work with ultrasound to characterize soft tissue injuries to improve outcomes of surgery. Nanyang Technological University Devante Horne and Bailey Walker, students of Dr. Frank Alexis were selected to receive the Summer Research Internship Fellowship by the Nanyang Technological University in Singapore. This university-wide research program was initiated to stimulate a culture of research for overseas undergraduates. Participants in this program will develop research interests, a strong sense of cross-cultural intelligence, a network of friends, and a better understanding of Singapore.

International Association for Dental Research Dr. Frank Alexis and his collaborator, Dr. Keith Kirkwood, Professor and Chair, Department of Craniofacial Biology at Medical University of South Carolina, were awarded the IADRs GlaxoSmithKline Innovation in Oral Care Award. The award is provided to recipients to advance oral care programs directed toward development of innovative and novel compounds, biomaterials, or devices that can be used ultimately at the public health level. NIH Center summer Clinical and Translational Research Course for Ph.D. Students George Fercana, a student of Drs. Aggie and Dan Simionescu were chosen to experience the following: How discoveries in basic science lead to applications in clinical and translational research; how clinical observations can elicit hypotheses that can be tested with basic science; the research resources, opportunities for research partnerships, and potential career opportunities for PhD students with the NIH. Lemelson-MIT National Collegiate Student Prize Competition Undergraduate Team Cure It Winners Tyler Ovington, Alex Devon, and Kayla Gainey, Team Glucosense, are developing the GlucoSense glucometer system, which could impact the lives of millions of diabetics worldwide who cannot afford current commercial systems. Under the mentorship of advisors Dr. Delphine Dean and Dr. John DesJardins, and with the support of Creative Inquiry, the team mentors dozens of high school students in South Carolina on class assignments and science fair projects ranging from dental-chair designs for resource-poor settings to education programs for women in Tanzania.

2014 National Science Foundation Graduate Research Fellowships Scott Cole, a senior, and Jonathan Matheny, a 2013 graduate now studying at Cornell University for his PhD, are 2014 awardees. Seniors Jessica Lau and Devleena Kole were awarded honorable mention. The NSF GRFP is the country's oldest fellowship program directly supporting graduate students in science, technology, engineering, and mathematics fields. Fellows receive an annual stipend, opportunities for international research and professional development, and have the freedom to conduct their own research at any accredited U.S. institution of graduate research they choose. National Institute of General Medical Sciences Dr. Naren Vyavahares team was recognized for developing nanoparticles that attach only to damaged fibers to deliver drugs to damaged blood vessels.

BMES Coulter College A design team including undergraduates Elliot Mappus, Tyler Ovington, Alex Devon, and Natalie Patzin and graduate students Xin Xie and Breanne Przestrzelski was chosen to present their at BMES Coulter College in New Orleans, LA. The college is a training program focused on translation of biomedical innovations. Student design teams are guided by faculty and clinical experts through a highly dynamic process designed to help them better understand how innovations can meet clinical needs while providing tools and approaches used to evolve identified problems into novel solutions. The team is taught by Dr. Delphine Dean and co-instructor Dr. John DesJardins and advised by Dr. Thomas Pace, orthopaedic surgeon at Greenville Health System.

Pioneering Use of Engineering Principles to Treat Disease The department is celebrating 50 years of awarding graduate degrees while helping prime the Upstate for what could be a boom in the medical-technology industry.

National Conference on Undergraduate Research Nora Hlavac, a student in Dr. Delphine Dean's lab, was chosen from a group of 4,000 undergraduate students to present her paper at the National Conference on Undergraduate Research. NCUR's mission is to promote undergraduate research, scholarship and creative activity. Upstate Biomedical Technology CUBEInC research projects could lead to major breakthroughs in the biomedical technology field, and the Upstate could be at the center.

NASA Pathways Intern Employment Program Trey Poole, a student inDr. Frank Alexiss lab, was awarded a fellowship by the NASA Pathways Intern Employment Program. He will work at Kennedy Space Center in Cape Canaveral, FL. American Council of Engineering Companies of South Carolina Devante Horne, a student in Dr. Frank Alexiss lab, was awarded an ACECSC scholarship recognizing his academic achievement and career potential in engineering.

Science Translational Medicine Dr. Frank Alexis is a lead author on a featured paper and inventor of oral delivery of nanoparticles coated with antibodies. Joseph A. Miller Jr. Memorial Scholarship Mr. Devante Horne, a junior in Dr. Frank Alexiss lab, was awarded the Joseph A. Miller Jr. Memorial scholarship. A single scholarship is awarded annually to a minority student who represents Dr. Miller's legacy of academic excellence and selfless commitment to others.

Symposium Endorsed by SFB As part of its 50th anniversary celebration, the department hosted leading researchers and industry representatives at the 2013 Clemson Biomaterials Symposium, Biomaterials Whats Next? The annual event is endorsed by the Society For Biomaterials University Innovation Fellow Epicenter, a National Science Foundation funded center managed by Stanford and NCIIA, has named Breanne Przestrzelski, a student in Dr. John DesJardinss lab, a University Innovation Fellow. She joins a group of 60 engineering student leaders at 56 universities who work to catalyze entrepreneurial activity on their campuses.

NIH F31 Mr. Gregory Wright, a PhD student in Dr. Hai Yaos lab was awarded the training grant by the National Institute of Dental and Craniofacial Research to study the biomechanics of the human temporomandibular joint.

NIH Roundtable on TMJ Biology Dr. Hai Yaoled the Roundtable, which was sponsored by several institutes of the National Institutes of Health. He was awarded a planning grant by the National Institute of Dental and Craniofacial Research to establish a multi-institutional TMJ research network. More.

Dare-to-Dream Medtech Design Challenge Finalist A device designed by Eric Lucas, a doctoral student in Dr. John DesJardinss lab,has been chosen as a top-10 finalist in a competition sponsored by the trade magazine Medical Device and Diagnostic Industry (MD+DI). Mr. Lucass device, The Engage Knee System, is a knee replacement that can be selectively locked in extension by patients with weakened knees and instability.

2013 Engineering World Health Design Competition In this challenge to provide healthcare in developing countries, Kayla Gainey and Tyler Ovington, students of Dr. Delphine Dean, won second place for their low-cost glucometer design.

One More Time: Medical Device Recycling is Good Business Clemson Bioengineerings Medical Device Recycling and Reprocessing, led by Dr. Melinda Harman and her colleagues has been cited as a unique platform for public-private partnerships.

2013 Winifred Burks-Houck Women's leadership Awarded Bria J. Dawson, Bioengineering Senior and PEER Mentor, has been selected as the undergraduate awardee for the 2013 Winifred Burks-Houck Women's leadership award sponsored by the Center for Enabling New Technologies Through Catalysis (CENTC). The Burks-Houck Women's Professional Leadership Award will be presented to Bria at the NOBCChE 40th Annual Conference in Indianapolis, IN on October 4, 2013. She was selected for this award on the basis of leadership experience, commitment to community, and for academic success.

Goldwater Scholarships: Scott Cole one of two Clemson awardees Cole, who works in Dr. Delphine Deans lab, developed a new method for synthesizing gold nanoparticles for applications in drug delivery and investigated how these nanoparticles impact cellular mechanical properties. His work has been accepted for publication by the American Chemical Society journal Sustainable Chemistry and Engineering.

Two Bioengineering Seniors Among Eight Clemson Students Presenting at ACC Patrick Ovington and Jacob Hammers, ACC International Academic Collaborative (ACCIAC) Fellow, presented their research results at the eighth annual ACC Meeting of the Minds Undergraduate Research Conference at Wake Forest University. The students were accompanied by Delphine Dean, assistant professor of bioengineering, and Barbara Speziale, professor of biological sciences and director of the Creative Inquiryprogram.

NSF Graduate Research Fellowship Program The NSF 2013 fellowships were awarded to two current and three former students, and a current student received an honorable mention: Awardees Nadine Luedicke and Hobey Tam are respectively students of Dr. Delphine Dean and Dr. Naren Vyavahare. Samuel Pollard, a student of Dr. Frank Alexis, received an honorable mention. Brittany Banik, Brendan Roach, and Molly Townsend are the three graduates who were awarded fellowships. The 2013 competition drew 13,000 applicants, from whom 2,000 awardees were selected.

Tau Beta Pi Danielle Martin, a student in Creative Inquiry: Designing Medical Technology for the Developing World, taught by Drs. Delphine Dean and John DesJardins, has been named a 2013-2014 Tau Beta Pi graduate student fellow.

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