Installation of new spectrometer gets under way on A&M campus

Eagle photo by Dave McDermand Workers carefully line up placement Thursday for a super-conducting magnet that arrived on Texas A&Ms West Campus.

A 100-ton crane sat outside Texas A&M Universitys biochemistry and biophysics building Thursday not an uncommon site for the construction-heavy campus.

But the cranes presence had nothing to do with raising another new building. Instead, it was there to lift a four-metric-ton, 800 megahertz Nuclear Magnetic Resonance spectrometer through an opening in the roof of the building.

The installation of the NMR, which will be complete in two to three months, puts A&M on par with other top national research institutions, Dr. Gregory Reinhart, head of the biochemistry and biophysics department, said.

NMR spectroscopy functions similar to the way an MRI takes images of the body, Reinhart said. NMR was developed first, and expanded into the imaging technique known as MRI. NMR, however, allows for higher precision for molecular information.

In NMR, we dont look at large objects, rather we look at individual molecules, like proteins and nucleic acids, Tatyana Igumenova, assistant professor and director of the NMR facility, said. This kind of instrument will allow us to determine the structure and dynamics of those molecules.

The NMR will be extremely powerful for research in drug design, Igumenova said.

You can identify potential drug candidates and use an NMR to determine where exactly they bind to the protein or enzyme, and what kind of effect they have on the structure and dynamics, Igumenova said.

With these capabilities, researchers will be able to design improved inhibitors to prevent the spread of disease.

The NMR, along with the upgrade and relocation of two other instruments to the NMR facility, cost a total of $2.7 million. The NMR itself cost more than $2 million, Reinhart said.

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Installation of new spectrometer gets under way on A&M campus

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