Healthy lifestyle in obese mothers can improve the baby’s health – Diabetes.co.uk

Obese pregnant women can reduce health-related risks for their unborn child by improving their diet and exercising, researchers have said.

Previous research trials have found high glucose levels in the pregnant mother can trigger changes in the fetus, therefore making the child vulnerable to health conditions in later life.

The most recent study involved more than 550 obese pregnant women. Half of them were asked to improve their diet and start exercising and the other half made no changes to their lifestyle at all.

The researchers looked at DNA patterns among children who were born to mothers who developed gestational diabetes and whether a dietary and physical activity intervention had altered outcomes.

The findings suggested that making lifestyle changes in pregnant did reduce DNA changes in the child which are usually associated with gestational diabetes in the pregnant mother.

Karen Lillycrop, Professor of Epigenetics at the University of Southampton said: These findings suggest that improvements to diet and physical activity can have an impact on the development of their children.

These are very encouraging findings and further studies are now needed to establish whether reducing these epigenetic changes through a healthier lifestyle during pregnancy are accompanied by improved health outcomes for the children in later life.

Professor Lucilla Poston, Tommys Chair of Maternal & Fetal Health and lead investigator of the UPBEAT trial at Kings College London, said: We have known for some time that children of mothers who had gestational diabetes are a greater risk of obesity and poor control of glucose; this new research implies that epigenetic pathways could be involved.

Tommys chief executive Jane Brewin said: Obesity during pregnancy can have lifelong negative impacts on mother and baby so one of the best things mums can do is to improve their health, including their weight, before embarking on a pregnancy.

However, this study shows that mums who are overweight and their babies can still benefit from adopting a healthy diet while pregnant. All mums-to-be need access to healthy eating advice, and those who are overweight should be given non-judgemental practical support and encouragement to eat healthily during pregnancy.

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CII, UR LIFE organise ‘Wellness Run’ to promote healthy lifestyle – United News of India

Hyderabad, Dec 13 (UNI) To celebrate 125 years of service to the nation Confederation of Indian Industry (CII) Telangana in association with UR LIFE organised a 'Wellness Run' from Novatel to Hitex, Madhapur, here on Sunday to promote a healthy lifestyle.

It was supported by Vijaya Diagnostics, Hyderabad Runners and HITEX.

Telangana Minister for Youth Services, Tourism & Culture V Srinivas Goud was the chief guest at the occasion along with Mr Mir Mohtesham Ali Khan, Mr World Silver Medalist 2008 and Bharat Gaurav Samman Awardee was the guest of honour during the flag-off.

Speaking on the occasion, Mr Srinivas Goud mentioned that we must make fitness a part of our daily regime as it promotes a healthy mind and body and urged all to remain fit for life.

He also launched the T-Fit Campaign to make a clarion call to all Telanganites to take up any form of the fitness regime for at least 20 minutes a day.

The 5K run saw participation from CXOs and professionals to celebrate fitness and health.

The runners were given a certificate and medallion on completion of the run.

The run was limited to 50 participants keeping in view the COVID protocols.UNI VV RHK1535

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CII, UR LIFE organise 'Wellness Run' to promote healthy lifestyle - United News of India

Make Your Kitchen Part of Your Healthy Routine | Spiritual and Physical Wellness – ChicagoNow

By Sheri McIntosh, today at 11:22 am

Eating healthy meals is one of the major components of creating a healthy lifestyle. Because of COVOID-19, eating out has been limited and we need to prepare meals at home. With preparing meals at home, we need to create a process that incorporates our kitchen. Now is the time to strategically stock your kitchen. Get rid of unhealthy and outdated items. Organize your kitchen with healthy foods including fruit, vegetables, nuts, and lean meats. Load your kitchen with spices. Different spices have health benefits including assisting with weight loss, improving brain function, reducing nausea and inflammation, and boosting immunity. Store healthy snacks including nuts, cucumber, carrot sticks, cherry tomatoes, and fruit. This will help you avoid eating unhealthy snacks like potato chips, snack bars, and crackers.

Whether you purchase your food online or in person, you need to plan. Plan your meals and purchase your food based on the meals you will cook for the week. Take time to create a shopping list. Creating a shopping list will help prevent making random purchases.

I like cooking so it is easy for me to plan meals. If you do not like to cook, search the Internet for quick recipes. There are also shortcuts you can take. I write a lot about not eating processed foods. There is one exception. You can purchase frozen vegetables that can be prepared quickly. There are studies that show frozen vegetables are just as healthy as fresh vegetables. Just make sure the vegetables do not have any added ingredients like salt or sugar.

You are in control when you prepare your meals at home. People who prepare their own meals usually eat healthier than people you eat out a lot. Also, preparing most of your meals at home is cheaper than eating out. There is nothing wrong with occasionally eating out. You should make living a healthy lifestyle your goal. Yet, having an occasional treat is okay.

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Kafer: Colorados vaccine distribution must prioritize those in crowded living conditions – The Denver Post

Should a child molester, rapist, or murderer get the COVID-19 vaccine before your grandfather does? For that matter, should convicts get the shot before the rest of us law-abiding Coloradans?

Did these provocative rhetorical questions and subsequent outrage cause the governor and the Colorado Department of Public Health and Environment to alter the states vaccine distribution plan to exclude incarcerated persons from receiving priority? Thats unfortunate.

If were going to frame complex public health decisions this way then we should also ask whether a 50-year-old obese diabetic should get the vaccine before a 62-year-old with a healthy lifestyle. Or, should a 90-year-old with advanced dementia living in a nursing home get the shot before a mother with leukemia who is raising five young children? Or, should a 60-year-old chain smoker with emphysema get the shot before a rehabilitated 34-year-old who is eager to rejoin society?

If these questions make you uncomfortable, they should. Who is in a position to weigh the value of anothers life? This is why the Colorado state vaccination distribution plan cannot be based on who deserves a vaccine as an individual but on what will achieve the greatest harm reduction for the whole community. It should prioritize protecting the most vulnerable to severe infection, shielding the health of indispensable workers like medical personnel, and preventing outbreaks among the most at-risk of catching and spreading the disease.

The initial plan released in October had six phases that balanced these priorities to ensure that the aged, the chronically ill, essential workers, and those living and working in close-quartered, transmission-prone environments such as prisoners received the vaccine before the general public.

The final plan now has four phases: this winter, medical personnel who work with COVID patients as well as staff and residents of long-term care facilities will get the vaccine followed by other health professionals, first responders, and correctional workers. In spring, vaccines will be available to people aged 65 or older and those with chronic conditions that make them more vulnerable to severe infection followed by people who work directly with the public and those who work in high-density settings such as meat-processing plans. Finally, the public will be vaccinated.

Whos missing from the final list? People in congregate housing such as prisons and college dorms were not included even though 14 of Colorados 15 largest coronavirus outbreaks to date were at correctional institutions or college campuses. This omission needs to be addressed.

The state has a legal obligation to provide medical care for the incarcerated under the U.S. Constitution and according to the 1976 U.S. Supreme Court case Estelle v. Gamble. Incarcerated people are four times more likely to contract COVID-19 as the general population because they live in close proximity according to a study by the Criminal Justice Commission, and they have higher mortality rates from the disease.

Because inmates are more vulnerable to catching and transmitting the disease they should receive a higher priority than the general public. They shouldnt be at the head of the line but they should be in line ahead of people like me who can effectively socially distance and are at lower risk.

Most people in Colorado prisons and jails are not child molesters, rapists, or murderers but regardless of their crime, a court and jury have already determined their penalty and they are serving it. We cannot deny this vulnerable population priority in the vaccine plan in order to punish them and confer their vaccine access upon a worthier group. We are not their judge and jury.

The Colorado Department of Public Health and Environment should revise the latest vaccine distribution plan to include a priority for inmates. Gov. Jared Polis should articulate why public health policy demands an unbiased risk assessment and response and how that will benefit all of us.

Krista L. Kafer is a weekly Denver Post columnist. Follow her on Twitter: @kristakafer.

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6 Healthy Habits To Boost Wellbeing And Quality Of Life – Longevity LIVE – Longevity LIVE

If you are the kind of person who is constantly on the move and doesnt pay much attention to your health and wellbeing, it is time to break from the robotic routine and pick up some healthy habits. Unfortunately, people often forget that a bad lifestyle can lead to severe health conditions which in most cases may result in undesired consequences.

The first step to changing this poor way of living is to accept that you must take matters into your hands. And the good news is that you dont have to make any drastic changes, but instead you can switch up your current routine and embrace a healthier lifestyle.

Whether it is increasing your water intake to stay hydrated or taking a walk more often, such small steps will certainly have a great impact on your life in the long run. So, if you are willing to change your life for the better, take a look at these simple habits you can build in order to boost your wellbeing as well as your quality of life.

It is well known that drinking water is the best choice for overall health and wellbeing. However, another alternative for a healthy beverage is tea. Herbal teas, in particular, are full of antioxidants and vitamins that help fight many diseases and infections, protect against oxidative stress, and enhance the immune system.

There are so many herbal teas to choose from. However, many people still prefer more traditional tea choices. So the herbal experts at Harney & Sons recommend Earl Grey tea for its many health benefits. It is a mix of black tea leaves and bergamot orange which gives this hot beverage a mild citrus-like taste. The bergamot extract consists of powerful antioxidants that have anti-inflammatory properties and immune system benefits.

Another herbal tea known for its calming effects is chamomile tea. Besides having antibacterial and anti-inflammatory properties, this tea serves as a sleep aid and relieves pain symptoms.

Jotting down your personal thoughts, experiences and goals is a great way to increase self-awareness. By keeping up with your daily journaling, you will be mindful of your strengths and weaknesses and able to come up with ways to better yourself in every area of your life.

The truth is keeping a daily journal has many benefits. Firstly, you will be able to record all of your ideas, goals, and ambitions in one place at any time and anywhere you want. Secondly, writing down your feelings and thoughts is a great way to relieve stress. By expressing yourself on paper you will free up any tension that may be preventing you from feeling happy.

Lastly, writing a journal unleashes creativity which means you can let your imaginations run wild and record each one at the same time.

Eating a well-balanced diet provides your body with all the necessary nutrients it needs to function properly. However, in order to improve your eating habits, you must make small lifestyle changes that you can keep doing over time.

For example, instead of gobbling down your food, you should take your time to chew it and enjoy it properly. By adopting this habit, not only will you enjoy the taste of your food more, but you will most likely eat less too.

Another eating habit that goes a long way in focusing on what you are eating and not on how many calories you are consuming with every meal. This is very important to know in order to be able to differentiate between good calories present in fruits, vegetables, and protein and bad calories present in sweets, fast food, and fizzy drinks.

One of the secrets to keeping your health intact is by engaging in regular exercises that control body weight and reduce the risk of developing health conditions.

If you are putting off exercising only because you dont like going to the gym, there are other fun activities you can take up to get your body moving. Whether it is playing tennis, doing yoga, or even taking dancing lessons, you should choose an activity that fulfills you and brings you enjoyment.

Besides this, you must remember to not overdo it and completely drain your body while exercising. Since most things in life come down to balance, moderate exercising is no exception. It is important that you listen to your body and slow down when you feel too exhausted so your body gets the rest it needs.

Another way to cope with stress is by taking up a new hobby. Generally speaking, having a hobby you enjoy can certainly enrich your life, fulfill your leisure time, and give you an opportunity to learn new skills.

The best way to develop a new hobby is to try something new. Remember that you cannot force yourself to like things, but instead, it should come to you naturally. Luckily, the world is full of exciting activities which can accommodate everyones taste. Whether it is drawing, cooking, gardening, or playing an instrument, you should choose something that interests you and allows you to be innovative.

In fact, one of the biggest advantages of having a hobby is that you will be relying on your creative side to explore new ideas and ways that can further help you with your personal growth.

In the past, people usually went to visit the doctor only if they werent feeling well. Nowadays, precautionary healthcare has become very important as it helps people stay on top of their health. Fortunately, many are becoming more proactive in getting medical advice about how to lead a healthy lifestyle.

Regular health checkups bring many benefits. Firstly, they help find potential health issues before they turn into serious problems. Early detection gives you a better shot at getting the right treatment and avoiding further complications. Consequently, they bring more awareness of your health conditions. This way you will be informed about your overall health. This will provide you with the opportunity to stay peaceful and stress-free.

So dont forget to add a routine health checkup to your lifestyle and keep track of your overall health.

All in all, adopting healthy habits is key to a long life. Granted, embracing them may be difficult at first. However, you will soon realize that they are in fact very beneficial for your overall health and wellbeing. So if you need help coming up with new healthy habits, keep this postmarked. Dont be shy to take up some of the ideas mentioned here.

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A step towards Veganism – The Hans India

As more and more consumers choose to live a healthier lifestyle, the demand for fitness and protein supplements are going to exponentially increase in number, without any roadblocks. With Make in India, all its products are Vegan (90%) and rest (10%) vegetarian.

Fitspire is an endeavor to grant its pre-eminent status in the field of health, fitness, activeness, agility, and well-being. It has wellness products for all demographics, the product lines include Sports, Health, Personal, and Child wellness suitable for all age groups and needs.

With the day to day challenges people often fail to consume proper nutrients, which eventually leads to common lifestyle diseases. To inspire people with a healthy lifestyle Fitspire is focused on delivering genuine, authentic, validated premium products for all age groups.

Nidhi Jain, Co-Founder Fitspire India's premium vegan and vegetarian health wellness brand shares, "Fitspire- aspire to fitness is an establishment that renders high graded, 100% vegan and vegetarian healthcare products to promote a better, healthier and nutritious lifestyle that are accessible, affordable to all.

Nutritional gap that our nation is facing which takes the lives of many people daily inspired me to begin this healthcare startup-Fitspire. I wanted to empower people and help others in my shoes. Our mission is to spread awareness about veganism and vegetarianism, aspire nation towards fitness and inculcate them around."

Fitspire wants its customers and consumers to embrace a way of living healthy and further create a path to empower women and make everyone aatmanirbhar to fit.

Night shares, "Before starting this journey of Fitspire, me and my team researched, did many surveys and came to the conclusion that India needs to have a strong foundation related to healthcare products. Nowadays new formulations of healthcare supplements and competitions in various segments are emerging which offer an ideal ground for the nation to think before buying any product. This was a major challenge for Fitspire and team."

We live in a non-vegan world, but things are changing rapidly. We have more people consuming vegan food and supplements. Moreover, have a wide range of people coming in and embracing this lifestyle and its benefits. We all have become increasingly mindful of our health, health and wellbeing of our family and that of our mother earth.

Being mindful of how we eat and live has become a priority in today's world and we're reshaping how we shop, cook and eat.

Veganism as a lifestyle can go a long track. Adopting a vegan lifestyle not only has personal health benefits, it also helps our mother earth. It has been found that cutting animal products and bi products from your lifestyle. Not just this, veganism also contributes towards nature in terms of reducing emissions into the environment.

Make up your mind before changing your lifestyle and remain genuine to your decision. Vegan diet limits the intake and use of all animal products and bi products is believed to be the most environment friendly among all trendy diets. It could be as sustainable as promised because production of animal products and bi products does produce a large percentage of greenhouse gases responsible for the climatic crisis happening globally while on the other aspect vegan diet is sustainable and beneficial for wellbeing as well as environment.

"Whenever the world comes out of this coronavirus crisis, one thing is for sure is that people's attitude towards many things will change, especially the food that they consume. The connection between COVID-19 and animal consumption has triggered people's mind worldwide. This will bound to make people more careful, smart and understandable towards going vegan. However, chances of people accepting veganism are still far-fetched, especially in our country India.

This pandemic has impacted Fitspire positively as we have researched and launched products according to the need and requirement of the nation. Our market strategy and consumer needs have refined positively though this crisis has shaken the world. We are even planning to launch a few more products further demanded by our customers," concludes Nidhi.

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A step towards Veganism - The Hans India

From United Way: Dale Association focusing on mental and physical health of Niagara County seniors during pandemic – Lockport Union-Sun & Journal

EDITORS NOTE: The Lockport Journal is once again partnering with the United Way of Greater Niagara to showcase local groups receiving support from the United Way.

Ever since the Dale Association was founded in 1951 by a group of dedicated community volunteers, our organization has maintained a long history of service to adults in Niagara County. The Dale provides a wide range of supportive services for older adults, as well as mental health counseling and caregiver support services. The United Way of Greater Niagara has been an important part of The Dale since 1962. Funding from UWGN supports health and wellness programs and services for our communitys older adults, which are provided at our Senior Centre in Lockport.

People want and have different needs when it comes to their health and wellness. The Dale Association helps older adults achieve safe and healthy lifestyles through services that encourage healthy aging, independence, and safe integration in the community. The focus of all activities is the prevention of health problems that can jeopardize independence and quality of life. Individuals who maintain an active lifestyle are healthier than those who become socially isolated.

The Dale Associations Senior Centre is a one stop shop for senior focused wellness activities and education, exercise and screenings. Because of UWGNs financial support each year, we can provide wellness programs that promote healthy aging and the prevention of health problems that jeopardize quality of life. Senior Centre activities encourage a healthy lifestyle through nutrition and wellness education; health screenings; fitness; and supportive services for the elderly. Additionally, services are available for individuals with specific needs such as vision and or hearing impairment support, dementia support, and caregiver support.

During 2020, The Dale Associations building closed temporarily due to the COVID-19 pandemic, however supportive services for the communitys members were maintained through telephone and telehealth services. A lifeline of sorts were the daily calls made to seniors who were homebound during the pandemic. Participants in Memory Minders received activity packets in the mail and follow-up phone calls were made to caregivers and care recipients to maintain the level of support families came to rely on. Early on during the pandemic, personal protective equipment such as masks were in short supply The Dale Association distributed hundreds of masks to individuals who did not have access to them otherwise. And, food and essential toiletries like toilet paper were collected and distributed to members and clients who were homebound and unable to get needed supplies. All services were provided in a safe and socially distanced manner in order to maintain connectivity to those who were isolated due to the pandemic.

The Dale Associations facility is back open and providing in-person services that promote healthy aging and the prevention of health problems that jeopardize quality of life. All in-person activities are at a reduced capacity, socially distanced, and adhere to all pandemic safety protocols including health screenings to enter and face masks. For individuals who prefer to receive remote support, telephone and telehealth services are still provided.

Because of the critical support provided each year by United Way of Greater Niagara, the Dale Associations Senior Centre is able to continue serving as a one-stop shop for seniors throughout our region, offering them a spectrum of wellness activities and education, exercise , screenings, social opportunities and other supportive services. The focus of all these services aids in the prevention of health problems that can jeopardize independence and quality of life of our areas eldest residents.

Maureen Wendt is the president & CEO of The Dale Association. To learn more about The Dale Association, please call (716) 433-1886 or visit daleassociation.com.

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From United Way: Dale Association focusing on mental and physical health of Niagara County seniors during pandemic - Lockport Union-Sun & Journal

LIVE WELL: Knowing the impact of cholesterol – Stillwater News Press

Cholesterol are fatty lipids found in the bodys tissues and blood plasma. Nearly 1 in 3 Americans have high cholesterol. Unfortunately, too much cholesterol can put you at a higher risk for heart disease and stroke. Cholesterol is a waxy, fat-like substance which is found in all the cells in your body.

Your body uses cholesterol to make hormones, vitamin D, and helps you digest food. Your body is very capable of making all the cholesterol it needs. However, you can also find cholesterol in foods that come from animals such as egg yolks, meat, and cheese.

Too much cholesterol can cause it to combine with other substances in the blood and form plaque. This plaque sticks to the walls of your arteries, which is why high cholesterol can be dangerous.

There are no signs and symptoms, so it is important to get your cholesterol levels checked, and to talk to your health care provider about how you can manage your cholesterol. Although there are no symptoms, some people may be at a higher risk than others. Individuals who suffer from type 2 diabetes, have lower high-density lipoprotein (HDL), which is also known as the good cholesterol.

This condition also increases low-density lipoprotein (LDL) or bad cholesterol, which cause serious issues. Obesity is linked to higher triglycerides levels, higher LDL cholesterol levels, and lower HDL cholesterol levels. Obesity can also lead to heart disease, high blood pressure, and diabetes. It is important to understand if you are at a higher risk for high cholesterol and to talk to your doctor about managing it. Although high cholesterol is very common and serious, it can be easily be managed by making a few lifestyle changes.

Individuals who eat a diet high in saturated fat and trans fat, may have higher cholesterol than those who do not. Cutting out foods that contain large amounts of saturated and trans fat can greatly improve your cholesterol levels. Staying physically active will also help you maintain a healthy weight. For those who have high cholesterol, participating in physical activity can help lower cholesterol and help make it easier to manage.

Smoking is another lifestyle choice that can increase your risk for high cholesterol. Smoking damages your blood vessels, which makes them more susceptible to collecting fatty deposits. Creating a healthy lifestyle for yourself by eating a healthy diet and exercising can greatly improve your cholesterol levels and help keep you healthy.

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How your diet could help boost immunity as COVID-19 and the flu loom – nj.com

Maybe youre popping vitamins and upping your intake of key nutrients in the hope of strengthening your bodys defenses against COVID-19 and the flu.

But is this a sound strategy?

We consulted Dr. Nora Zabel Tossounian, an internist at Hackensack Meridian Health Primary Care and Womens Health in Lodi.

She cautions against too many megadoses of vitamins or overeating a certain type of food just because it may supply a specific nutrient.

There are some good medical studies that support it and there are some that dont, she says of foods and supplements touted as immune boosters. The main thing that it boils down to is healthy lifestyle habits and the importance of good, balanced nutrition and exercise and sleep. Cant beat that.

A vitamin-based defense and clean eating may possibly help mitigate health risks on some level, but theyre not a substitute for wearing a mask, social distancing, avoiding crowds and washing your hands.

While some supplements may be advisable, Zabel Tossounian says we should start with our plates. Make that a moderately clean plate.

I always tell my patients to try to get the nutrients as much as possible from food thats minimally processed, she says.

Ditch juices in favor of whole fruit (in moderation), she says, and try to cut down on processed, refined and bleached carbohydrates.

That doesnt mean buying something just because it says natural or organic on the label.

Many people try to say, Well, these potato chips ... they say theyre natural, she says. Thats a processed carb.

Baking, a favorite pandemic pastime, can make us more vulnerable to reward eating. As we eat more carbs, our bodies produce more insulin to keep up with the sugar. Cookies can seem like a good quick fix for stress, but if we're trying to avoid inflammation, insulin spikes are not our friend. Steve Hockstein for The Star-Ledger

Zabel Tossounian points out that carbs in excess are problematic because they cause belly fat and weight gain and increase insulin levels.

What does that have to do with immunity?

Insulin is known to be a pro-inflammatory marker, she says. It can make it more challenging for our immune system to fight off infections.

Of course, starting in March, when grocery stores began to feel the strain of the pandemic, a whole lot of people were panic-buying chips, cookies and other treats. Even if the irony is a time-honored one, we were using unhealthy behavior to try to soothe our fears about the health crisis.

A lot of us during these stressful times tend to overeat or emotionally eat, Zabel Tossounian says. Mindful eating is so important. Sometimes we do make the wrong choice intentionally because we need to have that satisfaction.

If opting for oat milk, nut milk or other milk alternatives, look for products fortified with vitamin D. But this may not be enough to reach an optimal vitamin D level.Thomas Urbain | AFP via Getty Images

Want to enlist vitamin D in strengthening your bodys defenses?

Sources of vitamin D in your diet could include milk, cheese and yogurt. Zabel Tossounian tells her patients to stick with varieties that have reduced fat. Those who are lactose intolerant or vegan can opt for nut milks or milk alternatives like soy, almond, hemp and coconut. Oat milk has become one of the most popular, but check the labels.

Sometimes they may not fortify with vitamin D, Zabel Tossounian says. And even if they are fortified, the amount can be less than optimal.

The majority of patients in our practice tend to be vitamin D-deficient, she says. Many take supplements. (You can always ask your doctor to check your vitamin D level.)

Avocado on toast or not may have become a trendy food associated with the finances of millennials, but it is also a source of fiber, protein, healthy fat and vitamin C.Anna-Rose Gassot | AFP via Getty Images

Some studies in COVID patients have shown that (zinc) does help with the mechanism of the immune system fighting off this virus, Zabel Tossounian says. We also use it to a certain extent in certain hospitalized patients.

Natural sources of zinc include mushrooms, beans, chickpeas and nuts.

Most fruits and vegetables do have a fair amount of zinc, she says. Zinc is very important.

She tells patients who would prefer a supplement that they can try 50 milligrams of zinc a day.

Vitamin C is most traditionally associated with a perceived defense against ailments like the common cold.

Many patients during this time will down glasses of orange juice or take megadoses of vitamin C, Zabel Tossounian says. First of all, orange juice contains a lot of carbs.

People wanting to limit carbs should stay away or stick to one serving, she says. Those who are worried about acid reflux can avoid orange juice altogether in favor of a 500-milligram daily supplement. The catch: only do this if you can drink at least 64 ounces of water per day.

The reason for that is long-term, higher doses of vitamin C in some patients can increase the risk of kidney stones, Zabel Tossounian says. Another option is to only take a vitamin C supplement during the fall and winter months.

Salmon: a good source of protein and healthy fats.Eric Piermont | AFP via Getty Images

Zabel Tossounian says that in order to avoid lopsided diets that are too heavy on the carbs, for instance, she counsels patients to make one third of their plate low-fat protein, one third vegetables and one third minimally processed starch.

Salmon is a good go-to protein and supplies necessary healthy fats, she says. Another option is baked or boiled (not deep-fried) chicken as long as the skin is removed.

Vegans and vegetarians can opt for beans, bean-based pastas and avocado for protein (and healthy fats). They can also choose plant-based meat substitutes, though Zabel Tossounian says to watch the fat content on your favorite plant-based burgers. Either limit how many times theyre in the rotation or cut down on fats and oils elsewhere in your meal.

She tells patients to limit red meat ideally lean cuts to no more than twice per week.

About those processed carbs. A lot of patients have been coming to Zabel Tossounian with weight gain in the pandemic what some have been calling the COVID 19.

In the beginning of the pandemic, aisles that normally stocked flour and sugar were half (or all) empty since many people started baking.

They loved it and they did with their families, she said. As we know, food, in all cultures, is a way of connecting with your loved ones. The kitchen became the most important room in the entire home.

Has your kitchen become a production line for cakes and cookies in the pandemic?Sarah Rice | The Star-Ledger

Why not focus on food when you can plan your day around the meal youre going to have at night? Of course, that makes it easier to overeat or stray from good eating, especially if theres a sense of reward involved.

A lot of it comes from entitlement, Zabel Tossounian says. Had a bad day at work or had a difficult Zoom meeting? You know, Im entitled to that Snickers bar. It gives temporary satisfaction. All of us do it, were human.

She suggests eating clean 80 to 90% of the time and leaving a bit of room for indulgence.

More vitamin D and C may not mean much without vitamin sleep and exercise.

Moving for at least 30 minutes five days a week can help us feel better.

Why? Its not just the lack of guilt for not exercising were talking about here. The happy hormones, or endorphins, released during a workout can help to ease stress, anxiety and depression.

This 24 Hour Fitness gym in Springfield reopened in September. If you can't get to a gym or don't feel comfortable going, there are many free options for online workouts. Patti Sapone | NJ Advance Media

Another benefit of exercise is that when you start thinking about how many pushups you may need to cancel out a candy bar, you may think twice and temper emotional eating, Zabe
l Tossounian says.

Even if your gym has gone out of business, there are ways to stay fit in the winter. Zabel Tossounian often recommends that patients check out free resources like the YMCA 360 website, which has on-demand fitness videos, or workouts on the Nike Training Club app.

Some local gyms are still offering online classes and virtual memberships to a wide range of workout programs are available online.

Thank you for relying on us to provide the journalism you can trust. Please consider supporting NJ.com with a subscription.

Amy Kuperinsky may be reached at akuperinsky@njadvancemedia.com and followed at @AmyKup on Twitter.

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Self-Care Beyond The Face Mask – Longevity LIVE – Longevity LIVE

These days, it seems like we hear the word self-care just about every day. Usually, its accompanied by advice on how to slice the perfect cucumber rounds for an at-home facial or make your own bubble bath for a healing soak in the tub. Dont get us wrong, these are amazing tools to have in your self-care toolkit and you should employ them as often as possible but theres more to the story when it comes to self-care. From making changes to your diet to cutting out toxic relationships, were here to help you take self-care beyond the face mask.

Lets start with the basics. What is self-care, exactly? According to the International Self-Care Foundation (yes, that exists), self-care is defined as what people do for themselves to establish and maintain health, and to prevent and deal with illness. The organization goes on to define it as practices encompassing hygiene, nutrition lifestyle, environmental factors, socio-economic factors and self-medication. To put it simply, self-care is what you do for yourself to improve your physical and mental health.

Your diet should be a big part of your self-care routine. After all, its one of the primary things that affect the way you feel each and every day. To improve your diet and, in turn, your self-care, you need to formulate a custom diet that helps you feel as good as humanly possible. This means getting rid of foods that make you feel sick, bloated, tired, or guilty.

If you suffer from gastronomic discomfort or irritable bowel syndrome (IBS), you need to work on coming up with an IBS diet planthat helps you figure out whats triggering your issues. Many people find success with a low-FODMAP meal plan or elimination diets.

Cooking is one of the best ways to enhance self-care because it allows you to fully control what goes into your food, resulting in better health. It also leads to a boost in self-esteem. Set a goal for yourself to cook at home at least half the time to help minimize dining out, which sometimes leads to guilt and triggers stomach discomfort.

Lets not forget that cooking and dining can be a great stress management tool as well! Find ways to turn cooking into an activity of stress relief, whether it means hosting a dinner party or spending your Sunday baking something elaborate.

Finding healthy ways to handle stress throughout your daily life can drastically improve your self-esteem, relationships, and physical well-being. The goal should be to replace poor stress management tactics overeating, binge drinking, not getting out of bed for the entire weekend with more productive ones. All the while, remember to not be hard on yourself if youre not always successful!

By that, we mean you should have a little fun! There is simply no replacement for an afternoon of mindless enjoyment, whether it be with friends at brunch, the movies, the arcade, or playing a couple of hours of video games throughout the week. Simply spending time with friends at home is powerful enough to boost your self-esteem and make you feel happy.

This one is tough for a lot of people, but remember that you are entitled to your own space and time. If you need quiet time alone to recharge throughout the week, do not feel obligated to attend events or answer your phone! Healthy boundaries with family and friends can make you feel less zapped and overwhelmed, which means they are an essential part of your overall self-care strategy.

Who says playing games isnt good for your mental health? Playing sports, board games or video games is a proven way to release stress and feel happier. In fact, contrary to what many people think, there have even been some studies linking video gaming to positive mental health. The key, of course, is to play in moderation.

Try to remember that talking about your feelings and working out emotions is foundational to a good self-care routine, in part because it helps you release stress and experience feelings of support. Whether its chatting with friends or an online therapist, putting it all on the table is always a good thing.

Although it may sound shallow, the truth is that when you feel good about the way you look, you feel good about everything else in your life. Thats because looking good makes you feel empowered and leads to stronger feelings of self-confidence.

When it comes to self-care for the skin, face masks are just the tip of the iceberg. Try to think about how what you eat might be impacting your complexion. While the old adages about pizza grease and chocolate are probably true, there are some surprising foodstuffs (bread, popcorn, cupcakes, alcohol, spicy stuff) that may be causing breakouts.

In todays society, its so easy to get caught up in the massive (and massively expensive) world of cosmetic enhancements, but often, its the minor things that really go the furthest. Whitening your teeth, getting a fresh haircut, and wearing nice, clean clothes can make as big of an impact as Botox, veneers, or fillers!

Its important that you choose a style clothing, makeup, home dcor, etc.that accurately represents you and what youre all about. This will help you create a life where you feel comfortable and will even help satisfy your inner creativity. In other words, dont aim to be someone youre not, especially when it comes to your appearance!

If you really want to create a meaningful, positive impact on your self-care, youll need to look inward and focus on ways to enhance your lifestyle. Its not just about soaking in the tub or throwing on a face mask, though those things are great, too. Its also about looking at the bigger picture and creating a healthy lifestyle that sets you up for happiness and success!

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Self-Care Beyond The Face Mask - Longevity LIVE - Longevity LIVE

Dont miss these breakout sessions at TC Sessions: Space 2020 – TechCrunch

Ready to blast off and join thousands of attendees around the world atTC Sessions: Space 2020 on December 16-17? The event, focused on space technology and dedicated to helping early-stage startups succeed in this exciting yet daunting industry, features panel discussions and interviews with the top leaders, visionaries and makers on the planet.

Want to save $50? Buy your pass before Tuesday, December 15 at 11:59 p.m. (PT) to lock in the Late Registration price before rates increase.

While youll find many of these brilliant experts speaking from the Main Stage, dont miss the focused programming we have lined up for the Breakout Sessions. Thats where youll find our partners sharing their in-depth expertise on a range of topics. Check out these breakouts waiting to drop a galaxys worth of knowledge on you.

(all times in PST)

9:00 10:00 a.m.

Fast Money SMC Space Ventures, AFWERX and Space Force Accelerators

Learn how SMC Space Ventures, AFWERX and Space Force Accelerators work together to connect startups to government organizations and resources in the space industry.

10:00 11:00 a.m.Sponsored bySP8CEVC

Introducing the launch of the Worlds First Space Technology and Human Longevity focused Rolling Fund in partnership with AngelList

Fireside chat with the general partners and team from SP8CEVC covering the verticals of Space Technology and Human Longevity.

11:00 11:30 a.m.

Fast Money Working with the Army to Operationalize Science for Transformational Overmatch

Learn about DEVCOM Army Research Laboratory and the xTech Program of prize competitions that accelerate innovative solutions that can help solve Army challenges.

11:30 12:30 p.m.

Pitch Feedback Session

Join us for a pitch feedback session open to all startups exhibiting at TC Sessions: Space 2020 moderated by TechCrunch staff.

1:00 1:50 p.m.Sponsored byThe Aerospace Corporation

University Showcase Boldly Innovating in Space, for Space (Part One)

Technologies to Go Boldly in Space For the past half century, space exploration and technology has been earth-centric. Weve studied the earth, orbited the earth and sent images of distant places back to earth. In the coming decade, well embark on a new commitment: Were going to space to stay. Were committing to space commerce, space habitation and space exploration in order to not just stay in space, but to extend our human footprint into this solar system. To be successful, we need bold people and new technology to build and deploy the next generation of space capabilities. We need to capture these space opportunities, avoid potential threats and deliver on the promise of a multi-planet human race. This session showcases our partners USC and MIT, as they provide insight into their space programs. They are joined by university partners UCLA, ASU and Caltech, showcasing a range of emerging space technologies. Working with the Aerospace Corporation, these emerging capabilities can be evaluated and integrated into government space-faring missions for communicating, navigating and exploring in space with NASA, NOAA and the Air Force.

9:00 9:30 a.m.

Cislunar Space: Building a Self-Sustaining Lunar Economy

We are standing on the threshold of a post-scarcity human future. Cislunar space, the area between the Earth and the moon, holds the keys to a tremendous wealth of opportunities.

9:30 10:00 a.m.

Fast Money Advancing Space Technology with NASA SBIR

Learn about the Small Business Innovation Research (SBIR) and the Small Business Technology Transfer (STTR) programs powered by NASA.

10:00 10:30 a.m.

Fast Money NAVWAR SBIR/STTR Primer: The SBIR/STTR is a robust program designed to help small businesses address government needs while promoting commercialization. This session is dedicated to providing a primer on the program with tips on getting involved and getting engaged with the Naval Information Warfare Systems Command (NAVWAR).

10:30 11:00 a.m.

Fast Money Introduction to In-Q-Tels investing activities in the commercial space sector: In-Q-Tel is a strategic investment firm that works with the national security community of the United States. For 20 years, In-Q-Tel has served one mission: to deliver the most sophisticated strategic technical knowledge and capabilities to the U.S. government and its allies through its unique investment model. Over the past decade, In-Q-Tel has been one of the most active investors in the commercial space sector, with a broad investment thesis that touches many aspects of the sector. This session will provide an overview of In-Q-Tel as a whole, as well as a discussion of the firms activities in the commercial space sector.

11:00 11:30 a.m.

Fast Money Enabling a dual-use business model with Defense Innovation Unit (DIU)

Learn how you can take a part of DIUs development of on-demand access to space, persistent satellite capabilities and broadband space data transfer

11:30 12:30 p.m.

Starburst x TechCrunch Pitch Me to the Moon: Starburst Aerospace and TechCrunch are teaming up to launch a pitch competition like no other Pitch Me to the Moon. Think Startup Battlefield, but for space. Ten promising early-stage space startups (selected by Starburst) will have an opportunity to present their innovations live to a panel of high-profile judges from across the industry.

1:00 1:50 p.m.Sponsored byThe Aerospace Corporation

University Showcase Boldly Innovating in Space, for Space (Part Two)

Bold Missions For the past half century, space exploration and technology has been earth-centric. Weve studied the earth, orbited the earth and sent images of distant places back to earth. In the coming decade, well embark on a new commitment: Were going to space to stay. Were committing to space commerce, space habitation and space exploration in order to not just stay in space, but to extend our human footprint into this solar system. To be successful, we need bold people and new technology to build and deploy the next generation of space capabilities. We need to capture these space opportunities, avoid potential threats and deliver on the promise of a multi-planet human race. This session showcases our partners USC and MIT, as they provide insight into their space programs. They are joined by university partners UCLA, ASU and Caltech, showcasing a range of emerging space technologies. Working with the Aerospace Corporation, these emerging capabilities can be evaluated and integrated into government space-faring missions for communicating, navigating, and exploring in space with NASA, NOAA and the Air Force.

Whew, talk about a great lineup. You might say its out-of-this-world which raises the question: Can you hear a rimshot in space? Dont forget to peruse the rest of our programming in the event agendaand start planning your schedule now.

Pro Tip: Say goodbye to FOMO. Our virtual platform makes it easy to toggle between the Main Stage and Breakout Sessions. Plus, youll have access to video on demand, so you wont miss a beat (excluding the Expo Ticket).

Remember, late registration savings end on Tuesday, December 15 at11:59 p.m. (PT). We also offer discount passes for groups, students and government, military and nonprofit employees. Buy the pass thats right for you today!

Is your company interested in sponsoring TC Sessions: Space 2020?Click hereto talk with us about available opportunities.

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6 Longevity-Promoting Herbs and Spices To Add to Your Cooking Rotation – Well+Good

The term longevity refers to the number of years you live, and it does have a limit. Our bodies are not designed to live to 120 years, although many of us would like to live that long if we had quality of life for that long, says Gary W. Small, MD, the physician in chief for behavioral health at Hackensack Meridian Health in New Jersey and the former director of the UCLA Longevity Center.

In reality, the normal (and inevitable) processes of oxidative stress and inflammation are thought to contribute to our gradual decline in health as we get older. That doesnt mean were helpless when it comes to our health. In fact, the foods we eat every day play a major role in healthy aging and longevityand a few herbs and spices may be especially helpful.

Inflammation is a natural part of the immune response to fight infection and repair damage from injuries. Excess inflammationis associated with chronic diseases including cardiovascular disease, cancer, diabetes, kidney disease, and non-alcoholic fatty liver disease. We know that heightened inflammation and oxidative stress contribute to age-related diseases, says Dr. Small. If you look at a lot of studies and blood markers of inflammation, we find that age itself is often associated with heightened inflammation. Lifestyle habits, including poor diet, lack of exercise, stress, and a shortage of quality sleep play an important role in accelerating inflammation, he adds.

Thats where plant-based foods can come in. Plants naturally have anti-inflammatory and antioxidant properties, which Dr. Small says may play some role in healthy aging and longevity. This may slow down the process of aging as well as support the immune system and protect against chronic conditions that are more common with age, explains Rachelle Robinette, a clinical herbalist and holistic health practitioner (and host of Well+Goods YouTube show, Plant Based). While we dont know for sure exactly how many antioxidants we need to consume for these effects, studies show that people who consume these kinds of foods live longer and better, says Dr. Small.

That doesnt prove that consuming any one particular food or supplement will have enough of an effect on your inflammation levels to actually have an impact on disease, Dr. Small adds. Were always looking for a quick fix or magic bulletEveryone wants a remedy, but none can even work well if diet and lifestyle are not in place, adds Robinette. In terms of longevity, diet and lifestyle are going to matter more than any herb or supplement. Herbs work wonderfully as medicine, but they really are supplemental.

Caveats aside, some foods really do boast more concentrated levels of disease- and age-fighting compounds than othersand that certainly cant hurt in moderation when you integrate them into your cooking routine. Whats great about spices is it makes your diet more palatable, you want a diet thats nutritious but delicious, says Dr. Small. (Just remember: You should always talk to your doctor before starting any new supplement; some can be toxic at higher doses, especially if youre taking certain prescription medications.)

Ginger is the epitome of food medicine, as Robinette calls it. The compound gingerol in ginger is the source of most of the plants many benefits; it has powerful anti-inflammatory and antioxidant effects and may have anti-cancer properties. (Which, hello longevity!) The Mayo Clinic is currently investigating whether eating 2,000 mg of ginger a day for six weeks can boost the microbiome, aka the collection of bacteria, fungi, and viruses that make up a large part of the human body. That would be a big deal, Robinette explains, since your microbiome affects your overall health, including your brain, mood, and immune system.

Robinette recommends having ginger a few times a week as a fresh extract, grated into food, added to stir-fries, or sliced in a hot cup of tea. You can also try Robinettes recipe for ginger shotswhich may be especially helpful during cold and flu season. I do several shots per day in winter, she says.

Heres the step-by-step for making Robeinettes ginger shot to reap the benefits of the plant:

You cant talk about herbs for longevity without talking about turmeric. Another powerful antioxidant and anti-inflammatory spice, turmeric is where curry gets its flavorand the antioxidant compound curcumin. In 2018, Dr. Small authored a small double-blind studyshowing that taking two 90 mg curcumin supplements daily for 18 months improved memory and attention in older adults with mild memory problems. We did find it has a significant effectcompared to placebo, says Dr. Small, who is currently expanding the research to a much larger sample size across the U.S. While hes not sure exactly how curcumin works to boost brain health, my best guess is its the reduction in inflammation, he says.

Robinette points out that turmeric has been called a natural immunomodulator, or a substance that helps keep the immune system in check by boosting immunity when you need it and tamping it down to prevent excess inflammation involved in many chronic conditions. Some research suggests that turmeric could potentially even play a role in preventing and treating cancer, cardiovascular disease, metabolic conditions, neurological disease, and skin diseases.

Although it certainly doesnt hurt to enjoy more foods with turmeric, youll need to pop a curcumin supplement to get the full health benefits of the spice. For therapeutic purposes, you want to take higher doses, says Robinette. Try to take the supplement when you eat your meals, preferably with fat (like fatty fish or nuts) to increase the bioavailability of curcumin. (Just check with your doctor before you start supplementing to ensure it doesnt interact with any health conditions you have or medications you take.)

Heres even more intel on all the benefits of turmeric:

Spirulina is a type of cyanobacteria (or algae) thats grown in water and sold as tablets or in powder form. It contains a high amount of protein for a plant. And with loads of vitamins, including iron, potassium, zinc, calcium, and B vitamins, its almost identical, nutritionally, to mothers milk, Robinette adds.

Given that following a plant-forward diet is key to healthy aging, Robinette says supplementing with spirulina can be beneficial for healthy aging. Nobody eats enough plants. Supplementing with something thats really concentrated like spirulina is acheat way to get more greens. Just be sure to check your spirulina comes from a clean water source. Aim for a teaspoon per day, says Robinette; since spirulina has a seaweed-esque flavor, she suggests tossing it into pesto or any savory recipe with greens, like salad dressings, soups, or dips.

Jalapenos, cayenne, and other types of peppers contain capsaicin, a chemical compound that makes food spicy and has antioxidant and anti-inflammatory properties. Dr. Small points to a 2015 observational study of nearly half a million people in China, which concluded that people who ate more spicy foods were less likely to die of all causesand specifically of cancer, heart disease, and respiratory diseasesthan people who didnt or rarely ate these foods. The authors concluded the effect may be due to capsaicin.

How often should you hit the hot sauce? The Chinese researchers found that the benefits of capsaicin were cumulative; people who ate spicy foods six or seven times per week were least likely to die of any cause. But eating spicy meals even a couple of times a week seemed to have some benefit.

There are only a couple dozen plant adaptogens, including ginseng, that help increase the bodys resilience to stressors of all kinds. While you might associate ginseng with Traditional Chinese Medicine, its one of the oldest medicinal herbs used all over the world to support human health, Robinette says.

Robinson explains that adaptogens like ginseng micro-trigger the body, so it gets stronger over time to physical, emotional, and environmental stressors (like light and sounds). Its not impervious to stress, but youre better able to recover and not overreact, she says. Its helping move you between the sympathetic and parasympathetic states with more ease. Many of us are dealing with some level of stress these days, which can, over time, suppress the immune system and even shorten your lifespan by contributing to inflammation in the gut and disrupting sleep. Chronic stress is counterproductive for longevity in many ways, says Robinette.

Like most herbs, ginseng has antioxidant anti-inflammatory properties, says Robinette. A wealth of research suggests ginseng may have immunomodulatory and anti-cancer properties, and that it may even help control blood sugar in people with diabetes and improve learning and memory. Unlike most of the other herbs and spices on this list, you really need to take ginseng every day for an extended period of time to see benefits, says Robinette. You can enjoy it in any form, including tea, powder, capsule, and tincturejust be sure to talk to your doctor first, as ginseng can interact with some drugs (like warfarin and insulin).

The powerful phytochemicals, or plant antioxidants, in blueberries helps clean up free radicals, fighting the effects of inflammation that can in turn impact your health and longetivity. There are studies showing antioxidant foods like blueberries or pomegranatesshow moderate effects [on oxidative stress], though not as consistent or as big of an effect as we saw with curcumin, says Dr. Small. While were waiting to support this science, it certainly makes sense to try to consume colorful fresh fruits and veggies.

Wild blueberries, in particular, tend to be highest in gut-boosting fiber and antioxidants, says Robinette: They have more skin than grocery store blueberries (which are still good for you but bred to be sweet). Eat them fresh, sprinkle blueberry powder into your smoothies and cereal, or spread blueberry (or any other superfruit) paste onto toast like thick jam.

Oh hi! You look like someone who loves free workouts, discounts for cult-fave wellness brands, and exclusive Well+Good content. Sign up for Well+, our online community of wellness insiders, and unlock your rewards instantly.

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6 Longevity-Promoting Herbs and Spices To Add to Your Cooking Rotation - Well+Good

Global Stoma/Ostomy Care Market Trajectory & Analytics Report 2020: Focus on Stoma Quality of Life Paves Way for Increased Spending on…

DUBLIN--(BUSINESS WIRE)--The "Stoma/Ostomy Care - Global Market Trajectory & Analytics" report has been added to ResearchAndMarkets.com's offering.

Focus on Stoma Quality of Life Paves Way for Increased Spending on Stoma/Ostomy Care Products. Market to Reach $3.8 Billion

The global market for Stoma/Ostomy Care is projected to reach US$3.8 billion by the year 2027, trailing a post COVID-19 CAGR of 4.2% over the analysis period 2020 through 2027.

The growth will be driven by rapidly aging population increase in the number of operative procedures involving creation of intestinal stoma and the resulting focus shed on stoma quality of life. World's population is rapidly aging supported by the increase in longevity as modern medicine becomes increasingly effective in preventing chronic disease, and reducing mortality. Also, easy access to age-friendly primary healthcare and growing sophistication of healthcare infrastructure play key roles in longevity.

For the first time in human history the percentage of older people in the total population is continuing to increase. In addition to the aforementioned increase in life expectancy, falling fertility rates are accelerating the trend. The aging population creates massive challenges for the healthcare system since it means larger chronic disease burden.

Among the many diseases of the elderly such as dementia; arthritis; blindness; chronic bronchitis; motor neurone diseases; osteoporosis; Parkinson's disease; stroke; CKD; and Alzheimer's, incontinence and bowel obstruction caused by colorectal cancer and other diseases that require surgical removal parts of the rectum, anus and colon requires the highest nurse care and self-care management needs. Colorectal cancer is the leading cause for creation of stomas/ostomy accounting for 45.6% of the prevalence rate. Juxtaposed with this fact, the high prevalence of colorectal cancer, over 60% of the incidence rate, among the elderly aged over 70+ makes aging population a powerful demographic growth driver for stoma/ostomy care products.

Colostomy is the most popular type of procedure performed on 45.2% of ostomy patients in the 60+ age group, while Ileostomy is the second most common procedure performed on people aged over 60 with over 38.7% of ostomy patients in the 60+ age group having Ileostomy. Urostomy is performed on 16.1% of ostomy patients in the 60+ age group. The ostomy market also benefits from the increasing survival rates from colorectal and bladder cancer. Mortality rate from these cancers has improved considerably during the past decades, both for women and for men. Resultantly, the increasing life expectancy of people bodes well for the ostomy care products market, considering the chronic nature of the conditions and the increasing need to use ostomy products. The annual ostomy product costs per patient are estimated in the range of US$1,000 to US$1,200 on an on average globally.

Prices of ostomy products remain stable due to fixed reimbursement levels. Caring for stoma is extremely important given the high risk and financial burden of complications following ostomy surgery. Lack of proper ostomy care is the leading cause for hospital readmission rates and ER visits in the United States second to kidney transplants. Over the years, rising awareness and improving standards of ostomy care have helped drive the market for stoma/ostomy care products.

The field of stoma care is also evolving and improving with stoma care emerging into a unique field in nursing. Popularity and easy availability of specially qualified stoma care nurses; development of best practice guidelines; easy access to new clinical insights and tools are all helping to deliver the best possible care for stoma patients.

Among the noteworthy trends in the global market for ostomy bags has been the increasing tender based and bulk purchases of the bags by large hospitals and healthcare facilities with huge number of inpatients on whom ostomies have been performed and also patients with fresh stomas. In order to maintain uninterrupted supply of these bags for better ostomy care for inpatients, healthcare facilities have been following the tender-based procurement of the bags.

Key Topics Covered:

I. INTRODUCTION, METHODOLOGY & REPORT SCOPE

II. EXECUTIVE SUMMARY

1. MARKET OVERVIEW

2. FOCUS ON SELECT PLAYERS

3. MARKET TRENDS & DRIVERS

4. GLOBAL MARKET PERSPECTIVE

III. MARKET ANALYSIS

IV. COMPETITION

For more information about this report visit https://www.researchandmarkets.com/r/4d7qea

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Leading Healthy Aging Researcher Brian Kennedy, Ph.D., To Address Natural Health Industry On Impact Of Nutrition On Biological Age – PRNewswire

FERNANDINA BEACH, Fla., Dec. 9, 2020 /PRNewswire/ -- Ponce De Leon Health, Inc. ("Ponce de Leon"), a longevity research company focused on the reversal of epigenetic aging, announced today that Brian Kennedy, Ph.D., will speak at the SupplySide Network "Healthy Aging Never Gets Old" event on December 10th, 2020, at 1:00 PM Eastern.Doctor Kennedy is currently serving as Director of the Centre for Healthy Longevity, at the National University of Singapore.Registration for this free event can be found on theSupplySide Network 365platform.

Doctor Kennedy was invited to address industry leaders to discuss recent research which led to the development of Rejuvant LifeTabs, a dietary supplement designed for healthier aging. Informa Health & Nutrition named Rejuvant LifeTabs asthe top Consumer Packaged Goods winner in the Best Life-Span Specificcategory, at the 2020 NEXTY SupplySide Awards. According to Informa, Rejuvant contains "a ground-breaking ingredientLifeAKGand a meticulously researched, time-release formula tailored to men and women."

This news follows on the heels of Ponce De Leon Health announcement in September with the first peer-reviewed study of a non-drug substance demonstrating improvements in mammalian lifespan, reduction in frailty, and reduction in time of suffering. The results of the research were published in the September 1, 2020 issue of the journal Cell Metabolism. The researchers found that LifeAKG "promotes longer, healthier life associated with a decrease in levels of inflammatory cytokines. Strikingly, the reduction in frailty led the scientists to "propose that Ca-AKG compresses the period of morbidity." The publication, titled "Alpha-ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice," and was authored by Azar Shamirzadi, Ph.D., et al., and directly led to the development of Rejuvant LifeTabs.

Tom Weldon, the CEO and Founder of Ponce De Leon Health, remarked, "We're very proud of our research, past and ongoing, and committed to reversing epigenetic aging. Our product, Rejuvant LifeTabs, is emblematic of the growing discoveries in the field of epigenetics, or the changes made by modification of gene expression.We continue to conduct new human and animal trials to better demonstrate the benefits of Rejuvant on biological aging, healthspan and lifespan."

Todd Runestad, Senior Editor of Ingredients and Supplements, New Hope Media and Natural Products Insider, invited Dr. Kennedy to speak at the event.Said Mr. Runestad, "healthy aging is a prime consideration of supplement usersfrom specific health conditions like bone or joint or cognitive health, to the more general concept of aging gracefully. Of course, people have long sought out skin-health products, but the new frontier is the provocative research around epigenetics and nutrigenomicsthat one's lifespan is not just predicated on genetics, but that gene expression can be modulated by diet and specific dietary supplements."

Mr. Runestad added, "Brian Kennedy has been researching such concepts for decades now. He is one of the world's leading anti-aging researchers, and he may have come up with this decade's resveratrolthe fountain of youth molecule found in red wine. We awarded a NEXTY award for the year's best innovation, integrity and inspiration, to a supplement brand Dr. Kennedy helped develop for Ponce de Leon Health. The company's Rejuvant LifeTabs, coupled with an in-home genetic test kit, allows consumers the ability to actually track over time genetic markers of aging while taking the supplement. Personalized health care meets anti-aging science."

About Ponce De Leon HealthPonce De Leon Health (www.PDLHealth.com) is a commercial-stage longevity company focused on the discovery, development and commercialization of non-prescription consumer products to address the reversal of epigenetic aging. Their goal is to increase human healthspan, improve quality of life, and reduce the cost of providing late stage health care to customers.

To learn more about the groundbreaking science behind Rejuvant LifeTabsvisit http://www.rejuvant.com or follow @rejuvanthealth(Facebook), @Rejuvant (Twitter), or Ponce De Leon Health (YouTube).

SOURCE Ponce De Leon Health

http://pdlhealth.com

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Leading Healthy Aging Researcher Brian Kennedy, Ph.D., To Address Natural Health Industry On Impact Of Nutrition On Biological Age - PRNewswire

Biopharma Money on the Move: December 2 – 8 – BioSpace

December is bringing frost in the North and plenty of cold hard cash for these life sciences companies.

Forbion

European venture capital firmForbionrounded up$545 millionfor its fifthlife sciences fund. Investments will be made in about 15 therapeutics companies, with a third created byForbionthrough its Build opportunities. The rest will be invested in highly impactful existing companies.With offices in the Netherlands, Germany and Singapore, theplan is to invest about 80% into Europeancompanies and the rest in North American startups.

AbCellera

Since partnering with Eli Lilly to produce the first monoclonal antibody therapyapprovedfor mild-to-moderate COVID-19 patients,antibody discovery companyAbCellerais going big on the Nasdaq. Offering 23 million shares between $14-$17 apiecefor a hopeful total of$391 million, the company is lining up the biggest debut on record for a Canadian biotech.AbCellerasAI-powered antibody discovery platform speeds theotherwise lengthy and gruelingprocessby analyzing the database of natural immune systems to findantibodies that canbe developed into drugs.Thepromiseto partners is to move quickly. Reduce cost. Tackle the toughest problems in drug development. Investors include big names like Peter Thiel, Bill and Melinda Gates Foundation and more.

Silverback Therapeutics

Silverback goes for gold, upping its IPO for a4thtimesince the initial announcement. Originally slated for $125 million,the biotech is now shooting for a$241 millionraise by offering 11.5 million shares at $21 each. Some of the funds will be used for thedevelopment of therapeutics for oncology and other serious diseases through its proprietaryImmunoTACtechnology platform.TheImmunoTACplatform pairs proprietary payloads that modulate key disease modifying pathways with monoclonal antibodies directed at specific disease sites. Silverbacks lead candidate is currently in a Phase I trial in adults with HER2-expressing solid tumors.

Nuance Pharma

Theres nothing subtle about Nuances$181 millionSeries D financing round. The fully integrated pharmaceutical company creates value through Chinas specialty pharmaceutical markets with focus on iron deficiency, pain management and respiratory.Now poised to advance a robust therapeutics pipeline to clinical development, Nuance will use the funds for ongoing R&D of existing products and business development of potential new assets.

SigilonTherapeutics

Now live on the ticker,Sigilonhopes to sell 7 million shares fora$126 millionraise.Through its Shielded Living Therapeutics platform, the company is developing functional cures for chronic diseases. The companysproduct candidates consist of novel human cells engineered to produce the crucial proteins, enzymes or factors needed by patients living with chronic diseases such as hemophilia, diabetes and lysosomal storage disorders. The engineered cells are protected bySigilonsAfibromer biomaterials matrix, which shields them from immune rejection and fibrosis. In March, the company closed an $80.3 million Series B.

RayzeBio

Launched in October with a$45 million Series A,RayzeBioput a Series B on their Christmas list and Santa came early.With a pipeline of targeted radiopharmaceuticals against validated solid tumors, the biotech looks toutilizethe$105 millionraise into advancing their programs toward the clinic.Thecompanys goal is focused on improving outcomes for cancer patients by harnessing the power of targeted radioisotopes.RayzeBiois alsofunneling cash intoexpandingits HQ in San Diego with plans to further develop internal R&D.

SciNeuroPharmaceuticals

Cornering the untapped Chinese CNS market,SciNeurolaunched with$100 millionin their pocket. Headquartered in Shanghai, the company will also have a hub in Philadelphia.CEO and founder Min Li knows a thing or two from his time running GSKs neuro R&D group before the company shuttered the program in 2017.Li stated, One in every six people in China is living with a CNS condition, yet there are relatively few effective treatments available today, underscoring the urgent need to develop and deliver novel, effective therapies. The impact of CNS diseases extends beyond patientsto their families and society as well. Theassumption isSciNeurowill start with Parkinsons diseaseand painin addition to rare genetic diseases, after scaling up staffing.

BioAge

Looking to extend the humanhealthspan,BioAgeraised$90 millionin an oversubscribed Series C. The companyis at the forefront of understanding the biological drivers of aging with its unique and cutting-edge systems biology platform. A supporting pipeline has medicines to target these key pathways to reverse or eradicate disease and extend the years of healthy life remaining.BioAgeis on the cusp of takingpilot therapies BGE-117 and BGE-175 into clinical trials, targetingthe first half of 2021.According to a press release, proceeds from the financing will be used to build and develop a diversified portfolio of therapies that increasehealthspanand lifespan, augmentBioAgesartificial intelligence (AI)-driven approach to map the molecular pathways that impact human longevity, and further expand capabilities to test drug candidates in predictive models of human diseases of aging.

Remix Therapeutics

Laying down a new track for RNA processing, Remix launched with$81 millionin financing. Funds will be used to support development of theREMastertechnology platform and advance the companys pipeline of RNA processing targeted therapeutics as well.As we reach the limits of what is easily druggable with protein targeting therapies, reprogramming RNA processing represents an exciting new therapeutic opportunity. We believe we can precisely target the cellular complexes that process RNA to address the underlying drivers of disease, working upstream of protein expression, said Pete Smith, Ph.D., co-founder, president and CSO of Remix Therapeutics and Atlas Venture Entrepreneur in Residence.

Pear Therapeutics

Pear picked a sweet dealthis weekwith an$80 millionseries D backed by Temasek, 5am Ventures, Novartis andquite a fewmore.Combining biology and technology, the company specializes in Prescription Digital Therapeutics (PDTs),a new therapeutic class that treats serious disease alone or with drugs using software. PearsreSET,reSET-OandSomrystare the first PDTs to receive FDA approval for treating disease. The products are used to treat substanceuse disorder,opioid use disordersand chronic insomnia, respectively. Series D funds will be used to acceleratereimbursementcoveragefor its three commercial products.

Noema Pharma

Co-founded by the former VP of neuroscience for Roche, Noema Pharma raised$59 millionin a Series A round. With an intent to develop treatment for rare neurological disease whereexisting therapies have not shown much success, the company has licensed four clinical stage assets from Roche. The Roche-assets are aimed at seizures in tuberous sclerosis complex (TSC), trigeminal neuralgia, Tourettesyndrome and other rare neurologicaldisorders.Already having been in clinical studies at Roche, all four candidates have strong clinical and preclinical safety packages. Thisshouldallow Noemato quickly pursue a series of clinical programs in orphan central nervous system (CNS) indications.

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Biopharma Money on the Move: December 2 - 8 - BioSpace

Warm Up Your Content Strategy with a Human Touch – The Content Standard by Skyword

Content strategy pivots have been a normal response in the wake of COVID-19. As physical marketing spend shifts to digital channels, brands are looking to sales enablement and demand generation. But theres another, more subtle shift underway in the B2B world. Brands have begun embracing more of a human touchand in some cases, a conversational tonein their content strategies. Here are some emerging examples that can help point the way toward a new approach to your brand voice and communications.

How have your brands communications evolved in response to COVID-19? If your answer is not much, it may be time to reassess. During a recent visit to the Harvard Business Review, I used up my free allotment of articles. A banner ad invited me to log in or subscribe with a pithy headline: We hate paywalls too.

It was such a sharp, incisive take on the common complaints B2B readers haveand yet it caught my attention for the fun tone as well.

What does a banner ad have to do with communicating in 2021 and beyond? The world has undergone a seismic shifta fact thats leading many brands to reassess how theyre communicating. As the Harvard Business Review (HBR) notes, presenting with empathy and transparency is key. That can mean moving away from traditional messaging and finding a more authentic take on the situation unfolding.

The nuances of brand voice are more delicate than ever, says HBR. Brands that use this time to be commercially exploitative will not fare well. Better to do as Guinness did in the period surrounding St. Patricks Day, when the company shifted its focus away from celebrations and pub gatherings and instead leaned into a message of longevity and wellbeing. In these moments, we dont have all the answers, and we need to acknowledge that. If you make pledges, even during uncertain times, you have to be able to deliver on what you say.

If youre looking for creative strategies to take your B2B brand to a new level, consider these approaches.

Adding a human touch to content strategies runs the gamut from very simple to complex. Take a moment to consider how your buyers experience may have changed. Theyve traded busy days in the office and long commutes for endless Zoom calls, working while educating home-schooled children, and navigating a world that is more logistically complex than it was a year ago. Simple, straightforward communication eliminates barriers and helps people find the information they need quickly and efficiently.

The Marketing Insider Group recommends three basic tactics that serve marketers well in any B2B communication:

Just taking these initial steps will help ensure that what you create is clear, easy to digest, and capable of delivering real value.

Brands struggle to forge meaningful connections when they only create generic content that doesnt address their consumers realities. As Forbes notes, several brands in the B2B world have taken the opportunity to deliver what customers needed. Consider shipping, which was suddenly upended by increased demand, illness-related employee shortages, product out-of-stocks, and much more.

Forbes offered up the example of FedEx, which created clear, concise, and relevant communications for customers: Shipping was thrown into disarray with COVID, and many supply chains are still adjusting. FedEx, known for being one of the most trusted B2B companies, created numerous resources for small business owners, including templates for COVID signage, shipping discounts and expert advice and best practices. The company moved beyond just shipping to provide resources and guidance for the many new challenges small businesses face.

With physical sales and marketing opportunities like industry events and trade shows put on hold, partner networks are pushing for revitalization. One of the most important services that companies deliver to partners is crafting clear, concise marketing campaigns that drive demand with their audiences. In the past few months, that work has trended toward simple and streamlined campaigns.

Some now-emerging trends include:

As McKinsey notes, building capabilities for turbulent times not only helps you not only thrive, but it helps you pivot when unexpected changes arise. The authors note that maintaining a strong customer experience in crisis requires rapid research to understand changing dynamics and new pain points as well as agile innovation to address them. In a digital-led world, brand voice plays an important role in winning and retaining customers.

Recently, I worked with a customer to select a newsletter provider. The list included top brands across the newsletter industry. But after a frustrating demo with a sales rep and challenges navigating different complex web pages, the client chose Mailchimp. Its a good service, but not necessarily the one I expected them to select. When the CMO shared her rationale, it made sense. I could immediately understand everything they did and offered. The language was simple and easy to navigate.

Building your brand voice can help you reach frustrated, busy B2B buyers who need solutions to urgent problemsand who have less time, patience, and other resources to wade through reams of jargon-laden copy to find what they need. Mailchimp, by simple virtue of the brands clear, clean, and accessible content strategy, won a customer whos now singing their praises and sending along other busy executives in search of digital solutions they can implement and scale quickly. Investing in your brand voice is a capability that can grow and streamline business performance in unexpected ways.

Finding your voice through the end of 2020 and planning ahead into 2021 raises an important question for brand marketers: Does your content strategy have a human touch? Dont forget that your buyer has a completely different set of needs, expectations, and business realities than when you crafted last years content strategy. Add a human touchwith humor, clarity, and real talkto stand out and build connections that draw prospective buyers into your sales funnel.

Eager for more insights like this? Sign up for The Content Standard today.

Featured image by Andy Art on Unsplash.

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Warm Up Your Content Strategy with a Human Touch - The Content Standard by Skyword

Bestselling Author, Jill Wright, Celebrates Feature in Thriving Women Magazine With Presale of Codes of Longevity – Press Release – Digital Journal

Denver, CO, USA - December 11, 2020 - Author and CEO Jill Wright is celebrating more than the holidays this month. The bestselling author is featured in this month's issue of Thriving Women Magazine. The December issue is dedicated to longevity. Wright says that she is honored to have been selected to share her favorite ways to end 2020 in optimal health for an incredible new year to come.

"Living a long life well to enjoy this holiday season and many more begins in this moment now," explains Wright. "Small steps, little actions, done over time amplify to create your long and thriving life." Because of this, Wright is celebrating her feature by releasing her Codes of Longevity on Kindle Presale for 99 cents.

Codes of Longevity is packed full of practical and tactical solutions. This book is the bridge between science and the soul. Connecting the dots between lifespan, healthspan, and wellspan through epigenetics reveals how the pieces of a long life lived well all fit together for one's personalized longevity blueprint. Readers will learn how to achieve the most powerful age-defying results beginning today as they harness their potential to live limitlessly and be ageless.

Each chapter represents the foundational codes to longevity that, when leveraged, allows the reader to be ageless. To unlock their code, Wright has included a complete longevity blueprint assessment. This will give readers an immediate action plan of the opportunities available for them to take so they can flourish and thrive to 120 and beyond.

The book is available for presale online at https://amzn.to/3gcGwEX. Wright's feature in Thriving Women Magazine can be read for free, online, at https://bit.ly/2VGCBag.

About Jill Wright

Jill is affectionately known as the Queen of shine. She is a heart centered leader and CEO of Executive Shine and has been recognized by both Forbes and Harvard business review for transforming the culture of client based services. As a thought leader and best selling author, she shares her 33 years of experience by speaking and consulting to inspire other leaders to unleash the human potential within their organizations through the power of belief and authentic connection. Get her free gift, 7 secrets to Authentic Human Connection at http://www.Theshinegift.com.

Media ContactCompany Name: Vedette Global MediaContact Person: Angel TuccyEmail: Send EmailPhone: 720-257-9293Country: United StatesWebsite: http://vedetteglobalmedia.com

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Bestselling Author, Jill Wright, Celebrates Feature in Thriving Women Magazine With Presale of Codes of Longevity - Press Release - Digital Journal

As early as Tuesday, the coronavirus vaccine arrives. Who’s first in line, and what we know about who’s next – The Columbus Dispatch

Anne Saker|The Columbus Dispatch

With the scheduled Tuesdayarrival of dozens of dry-ice coolers, Ohiowill deploy a new defense against the novel coronavirus vials of vaccine invented, tested and put into service in record time. Here's what we know about who is in line for the vaccines, as well as their distribution and storage.

For at least the first three weeks of availability, the Ohio Department of Health has directed that only people to be vaccinated are:

All vaccination will be voluntary since the vaccines are still considered experimental.

>>Read More: With flu season off to mild start, experts say 'twindemic' is less likely but still possible

It's not clear yet the order of vaccination after Phase 1A. The states are waiting for the U.S. Centers for Disease Control and Prevention, which is developing the guidance, to recommend who is next,but the Ohio Department of Health has a draft plan that lists priorities.

Phase 1B would vaccinate older adults living in congregate or overcrowded settingsand people at significantly higher risk for COVID-19 because they have underlying health conditions.

>> This story is being provided free as a service to our readers during the coronavirus pandemic.You can find more stories on the coronavirus here.Please consider supporting local journalism with a subscription.

Phase 2 is where the jockeying comes in. This expansion of vaccination would include:

Critical risk workers essential to society (e.g., health care and public health operations and human services operations) and at high risk of exposure. This phase would also include:

Phase 3 would cover young adults, children, workers in essential industries and occupations not included in phases 1 and 2. Phase 4 is everyone else.

Because the initial quantities of the vaccines will be limited, public health officials urge maintaining vigilance about mask-wearing, hand-washing and social distancing. It could be at least a year before enough people are vaccinated to ease the health safeguards.

The clinical research has shown that the vaccine candidates do not generate severeside effects two months after the second injection. The shots might come with temporary side effects such as fever and muscle pain,a signal that the vaccine successfully triggered an immune reaction for the virus to be blocked.

CVS Pharmacy, Walgreens and two other private companies will be delivering and administering the vaccinations to nursing homes.

>>Read More: Ohio announces plans for initial COVID-19 vaccine distribution; DeWine tours warehouse

What we dont know: Whos precisely is next in line for the vaccine. Unions for grocery workers and other organizations for essential workers are jostling for the chance.

What we won't know for quite a while: How long immunity from the vaccine will last. The vaccineswere invented, put through clinical trials and brought to market inside a year. We don't have enough information about the longevity of theireffects.

Ohio COVID-19 vaccines: What to know about Pfizer vaccine distribution

Ohio is preparing to receive its first shipment of COVID-19 vaccines in the coming weeks. Here's what you need to know.

What we know: Right now, the Pfizer vaccine is expected to get emergency use authorization from the U.S. Food and Drug Administration at any moment and another one from Moderna is expected to be authorized in the next few weeks.But, public health agencies and hospitals, with long experience in planning vaccination campaigns, didn't wait for FDA approval to get ready. The delivery systemis set up and ready to receive the doses.

The two leading candidate vaccineseach pack slightly different pieces of genetic material from the virus. When injected, the messenger RNA makes the human immune system familiar enough with the virus to fight it off.

The vaccines dont prevent infection. But they stop it from progressing into the disease COVID-19, which has killed at least 290,000 Americans, including more than 7,200 Ohioans.

The vaccines are taken in two doses, like the two-shot series for shingles. The coronavirus vaccines, because they carry genetic material, require super-cold temperatures from the factory to distribution. The vials are packed in dry-ice coolers, a huge boost to Cold Jet based in the Cincinnati suburb of Loveland. For more than 30 years, the company has built dry-ice makers, and in 2020, sales have exploded more than 200% over 2019, said spokeswoman Lauren McNutt. Strong demand is expected well into 2021.

The vaccine manufacturers are the New York giant Pfizer working with the German company BioNTech and the Cambridge, Massachusetts-basedfirm Moderna. Both companies ran Cincinnati test sites for the final clinical trials and Pfizer enrolled test subjects in Columbus. AstraZeneca, which is working on another promising COVID-19 vaccine, enrolled trial participants at Ohio State University's Wexner Medical Center.

Last week, Gov. Mike DeWine announced the delivery schedule for Ohio.

On Tuesday, Pfizer delivers 9,750 doses to 10 Ohio hospitals, including Ohio State University Wexner Medical Center and OhioHealth Riverside Methodist Hospital,and 88,725 doses to Walgreens and CVS Pharmacy across the state, which will supply nursing homes.

On Dec. 22, Pfizer delivers another 123,000 doses for nursing homes and staff. Moderna delivers 201,000 doses to 98 hospitals for health care workers caring for COVID-19 patients and 108 health departments for emergency medical service workers and other first responders.

>>Read More: After decade-long fight for a new heart, central Ohio man sees COVID as his next test

The next week, the exactdate is not certain, Pfizer delivers another 148,000 doses and Moderna another 89,000 for workers and patients in hospitals and nursing homes.

What we dont know: These delivery totals are for the whole state. Its not clear yet how the shipments will be further divided for each of Ohios 88 counties, a decision that rests with the Ohio Department of Health.

Federal and state authorities have not released information on vaccine shipments past the end of December.

What we know: The cold chain doesnt stop at delivery. Pfizers vaccine candidate must be shipped and stored at minus 94.Once transferred to refrigeration to thaw for injection, it must be used within five days. Modernas candidate must be shipped and stored at minus 4 but can be stored for six months. Once in refrigeration, it keeps for up to 30 days.

Ohio hospital officials say they have the storage capacity for their doses of vaccine.

When the statedecides on how to apportion the doses as they arrive at county facilities, local public health officials from other jurisdictions can collect their shares.

Columbus Public Health has been preparing for the vaccine for months, said spokeswoman Kelli Newman. The city health department bough additional cold storage units in anticipation of the vaccine and the possibility of unique storage needs, Newman said.

"We have them in place and we are ready to go," Newman said."Once we receive the vaccine, we will be ready to distribute it strategically and equitably, beginning with those most at risk for COVID-19 complications and those working on the front lines during the pandemic."

Likewise, Franklin County Public Health has also beefed up its cold storage options for vaccines, said spokeswoman Mitzi Kline. The county health department hasordered one commercial grade refrigerator, two commercial grade freezers and several portable freezers, Kline said.

What we dont know: The location of the vaccine distribution warehouses isn't being disclosedto protect people, equipment and the doses.

Dispatch reporter Max Filby contributed to this story.

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asaker@enquirer.com

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As early as Tuesday, the coronavirus vaccine arrives. Who's first in line, and what we know about who's next - The Columbus Dispatch

Jerry Seinfeld: Success is the enemy of irritability and crankiness how to stay productive and motivated – CNBC

It's been more than 20 years since Jerry Seinfeld's eponymous television show, which ran for nine seasons, ended. But Seinfeld, 66, still works as a comic and made $51 million dollars in 2020, according to Forbes.

So to what does Seinfeld credit his creativity and career longevity? "Having a very cranky nature," he said during a recent episode of the podcast, "The Tim Ferriss Show."

While Seinfeld may have been partially joking, he does have a process. Here the tips that keep Seinfeld motivated and you can use them, too.

Seinfeld said the majority of his job requires writing, editing and developing jokes, often re-writing every word in a joke several times on a legal pad until it feels perfect. Indeed, "work time" can be incredibly frustrating and occupying, he said.

But that's the same drive that keeps Seinfeld working: "Success is the enemy of irritability and crankiness," he said. "Because now you have money, and you can remove the difficulties from your life and that's not good."

As someone who has made a lot of money, Seinfeld said, "the thing that did that really solve almost all of that issue is I got married," he said. Being married and having kids means that the material will "never run out," he said.

"If you're going to write, make yourself a writing session," or a determine a digestible time that you're going to use to write or work on something, Seinfeld said. For example, you could set an alarm for 30 minutes or 10 minutes, depending upon what you feel like you can handle.

"Don't just sit down with an open ended," he said, "that's a ridiculous torture to put on a human being's head."

When you have an end point in sight, it also creates a reward to strive for, Steinfeld said on the podcast. "If you have the guts and the balls to sit down and write, you need a reward at the other end of that session," he said.

To stay organized, Seinfeld said he has two phases of writing: "the free, play, creative phase, and then there is the polish and construction phase." He often sits down with "15 or 20 pages of stuff that's in various stages of development," plus a smaller notebook with random notes and ideas, he said.

An idea "is like an archery target 50 yards away," he told Ferriss. "I take out my bow and my arrow, and I go, let me see if I can hit that." On a good day, he said he'll write about half a page of a legal pad.

Seinfeld likes to spend "inordinate amounts of time refining and perfecting every single word" until he's ready to share his material.

In fact, Seinfeld said he has a rule that he won't show people his writing right away. "I will always wait 24 hours before I say anything to anyone about what I wrote," he said. That way, he can enjoy the satisfaction of having written something, without another person's opinion getting in the way.

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Jerry Seinfeld: Success is the enemy of irritability and crankiness how to stay productive and motivated - CNBC

Oxford Covid vaccine to be combined with Sputnik jab for trial – The Guardian

UK and Russian scientists are to test whether combining shots of the Oxford/AstraZeneca and Sputnik V coronavirus vaccines could result in better protection than two doses of the same one.

Trials will start by the end of the year, the Russian Direct Investment Fund (RDIF), which funded the development of the Sputnik V vaccine by Russias Gamaleya Institute, said on Friday. AstraZeneca confirmed that it was considering how it could assess combinations of different vaccines, and would soon begin exploring with the Gamaleya Institute whether their two vaccines could be successfully combined.

Like the Oxford/AstraZeneca vaccine, the Russian Sputnik V shot is based on a modified version of adenovirus, a common cold virus. This vector is stripped of any disease-causing genes and modified to carry genetic instructions for making the coronavirus spike protein, which it passes to human cells. The manufactured coronavirus spike protein then triggers an immune response that protects against the Covid-19 disease.

A potential problem with such vaccines, however, is that of anti-vector immunity, where if the immune system has previously encountered the type of adenovirus used in the vaccine, it may destroy it before the vaccine can trigger an immune response. This is why the Oxford University group chose to use a chimp adenovirus, rather than a human one. However, anti-vector immunity could also reduce the efficacy of booster shots, if this involves injecting the same virus for a second or third time.

Mixing and matching different vaccines may provide a solution. This concept is known as a heterologous prime-boost, and has been used in vaccination programmes against other diseases.

Now that the UK has authorised the first Covid vaccine, who will get it first?

The governments Joint Committee on Vaccination and Immunisation (JCVI) says its priority is to prevent Covid-related deaths and protect health and social care staff and systems.

Elderly care home residents and their carers are first on the JCVIs list because their risk of exposure to the virus is higher and because the risk of death closely correlates with older age. They are followed in priority by anyone else over 80 and frontline health and social care workers.

Even so, for pragmatic reasons NHS staff are likely to be the first group to receive the Pfizer/BioNTech jab. This is because the vaccine needs to be stored at ultra-cold temperatures, which can be achieved more easily by using hospital facilities

Are there enough doses to reach all the priority groups?

Together, care home residents, their carers and the over-80s make up nearly 6 million people, and frontline NHS staff a further 736,685. Matt Hancock, the health secretary, has said he expects 10m doses of the Pfizer/BioNTech vaccine to be available this year, so if this is the only vaccine authorised, everyone else would have to wait until further doses become available next year.

Where will I go for the vaccine?

Covid-19 vaccines are expected to be delivered at three types of venue: NHS trust vaccine hubs at hospital sites; mass vaccination centres, which are in the process of being set up at places such asfootball stadiums, conference buildingsand racecourses these are expected to vaccinate up to 5,000 people a day; and at GP surgeries and pharmacies. GPs can also visit care home residents and housebound patients at home without them needing to travel.

How far apart will the two doses be administered, and will I protected after the first?

While there is some evidence to indicate high levels of short-term protection from a single dose of vaccine, a two-dose schedule is what has been approved by theMHRA.

The second dose will need to be delivered at least 21 days after the first, and both will be injected into the deltoid muscle the thick triangular muscle we use to raise each arm.

For the Pfizer vaccine, its efficacy rate was calculated seven days after the second shot. It is likely that people will have some protection before this, but this is how long it will take for full protection to kick in. We will learn more about the extent of protection and how long it lasts as data from ongoing clinical trials comes in.

Can I pay to get the vaccine privately?

Unlikely. Englands deputy chief medical officer, Jonathan Van-Tam, has said he believes Covid-19 vaccines should be delivered according to clinical priority rather than allowing people to jump the queue if they can afford it.

Will I be able to choose which vaccine I have?

Also unlikely, at least in the short to medium term. Assuming more than one vaccine is approved, the priority will be distributing any available doses to the people who need it as quickly as possible.

Linda Geddes

Unlike AstraZenecas vaccine, Sputnik V uses two different human adenovirus vectors to try to trigger a stronger and longer-term immune response. It is not yet clear which of these components will be tested alongside the AstraZeneca vaccine.

Anti-vector immunity could also provide a possible explanation of why the AstraZeneca vaccine appears to work better when given as a half-dose followed by a full one, rather than two full doses.

Earlier this week, the outgoing chair of the UKs vaccine taskforce, Kate Bingham, announced that a trial of AstraZenecas vaccine in combination with the Pfizer shot was likely to begin in January. Its to do with trying to trigger the immune response and the durability [of the response], she said.

RDIF said it approached AstraZeneca about the possibility of combining its vaccines on 23 November.

This could eventually extend the duration of immunity and possibly also protect against people receiving the same vector repeatedly and having a less robust response, said Beate Kampmann, the director of the vaccine centre at the London School of Hygiene & Tropical Medicine. But for now these are all theoretical concepts that need to be carefully tested before they can be extended to population use.

Russia is likely to see the move as a vote of confidence by a western manufacturer in Sputnik V, which is already being used to immunise medical workers, teachers and social workers. Russian officials previously announced that the vaccine had more than 95% efficacy, giving it a success rate comparable to vaccines being developed by Pfizer and Moderna.

The decision by AstraZeneca to carry out clinical trials using one of two vectors of Sputnik V in order to increase its own vaccines efficacy is an important step towards uniting efforts in the fight against the pandemic, said Kirill Dmitriev, chief executive of RDIF. We hope that other vaccine producers will follow our example.

Dr Stephen Griffin, associate professor in the school of medicine, University of Leeds, said: The importance of a second jab should not be underestimated as it is important for the longevity, specificity and effectiveness of the response to most vaccines.

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Oxford Covid vaccine to be combined with Sputnik jab for trial - The Guardian